Cited by 2,137Acute Ischemic Stroke ManagementCardiovascular Health and Risk FactorsGlobal Health and Epidemiology

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Global Burden of Stroke

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Katan, Mira, Luft, Andreas·2018·Seminars in Neurology

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Abstract

Stroke is the second leading cause of death and a major cause of disability worldwide. Its incidence is increasing because the population ages. In addition, more young people are affected by stroke in low- and middle-income countries. Ischemic stroke is more frequent but hemorrhagic stroke is responsible for more deaths and disability-adjusted life-years lost. Incidence and mortality of stroke differ between countries, geographical regions, and ethnic groups. In high-income countries mainly, improvements in prevention, acute treatment, and neurorehabilitation have led to a substantial decrease in the burden of stroke over the past 30 years. This article reviews the epidemiological and clinical data concerning stroke incidence and burden around the globe.

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“(1) Based on the three groups mentioned above, we used the T test or Wilcoxon rank-sum test to identify di erential lipid species in each group.”
BackgroundMethodInfluential
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Cai, J., Xu, H., Xiao, R., Hu, L., Xu, P., Guo, X., Xie, Y., Pan, M., Tang, J., Gong, Q., et al. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1023089 · Cited by 25
“The exclusion criteria included: (1) studies that recruited <5 participants in the rescue stenting arm; (2) studies that reported the outcomes but with missing and insufficient data for analysis; (3) studies that were reported in the form of conference abstracts, research letters, or news reports.”
BackgroundMethod
Assessment of cerebral autoregulatory function and inter-hemispheric blood flow in older adults with internal carotid artery stenosis using transcranial Doppler sonography-based measurement of transient hyperemic response after carotid artery compression
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“Ath-erosclerotic CAS is a leading risk factor for ischemic stroke, which is a major cause of mortality and long-term disability in developed countries [6–8].”
Background
Astrocyte‐like subpopulation of NG2 glia in the adult mouse cortex exhibits characteristics of neural progenitor cells
Janečková, L., Knotek, T., Kriška, J., Heřmanová, Z., Kirdajová, D., Kubovčiak, J., Berková, L., Turečková, J., Garcia, S. C., Galušková, K., et al. (2023) · Glia · doi:10.1002/glia.24471 · Cited by 26
“Ischemic stroke is the leading cause of disability and death worldwide (Katan & Luft, 2018; Virani et al., 2021) and treatment options for this disease are still very limited (reviewed in Rabinstein (2017)).”
Background
Towards precision nanomedicine for cerebrovascular diseases with emphasis on Cerebral Cavernous Malformation (CCM)
Perrelli, A., Fatehbasharzad, P., Benedetti, V., Ferraris, C., Fontanella, M., Luca, E. D., Moglianetti, M., Battaglia, L., & Retta, S. F. (2021) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2021.1873273 · Cited by 24
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Chen, Y., Lin, K., Li, Y.-C., & Lin, C.-J. (2023) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-023-01151-6 · Cited by 24
“Background Stroke is a leading cause of disability that requires longterm post-stroke care and rehabilitation [1].”
Background
Analysis of onset-to-door time and its influencing factors in Chinese patients with acute ischemic stroke during the 2020 COVID-19 epidemic: a preliminary, prospective, multicenter study
Liao, Y., Qi, W., Li, S., Shi, X., Wu, X., Chi, F., Xia, R., Qin, L., Cao, L., & Ren, L. (2024) · BMC Health Services Research · doi:10.1186/s12913-024-11088-8 · Cited by 24
“The global burden of stroke has increased markedly over the past 20 years, especially in developing countries [11].”
Background
The impact of social relationships on the risk of stroke and post-stroke mortality: a systematic review and meta-analysis
Meng, M., Feei, Z., Zhou, H., Xie, Y., Lan, R., Zhu, S., Miao, D., & Shen, X. (2024) · BMC Public Health · doi:10.1186/s12889-024-19835-6 · Cited by 32
“…both mortality and disability on a global scale [1, 2], imposing substantial burdens on individuals, families, and healthcare systems alike [3]. ramifications of stroke surpass 1.6% of the global GDP [4], with incidence rates of associated conditions steadily climbing due to population aging [5].”
BackgroundInfluential
Rehabilitation Transition Program to Improve Community Participation Among Stroke Survivors
Bollinger, R. M., Krauss, M. J., Somerville, E. K., Holden, B. M., Blenden, G., Hollingsworth, H. H., Keleman, A. A., Carter, A. R., McBride, T. D., Barker, A. R., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.37758 · Cited by 24
Metabolic reprogramming and astrocytes polarization following ischemic stroke
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“, 2013), which limit their ability to perform basic activities of daily living (Jönsson et al., 2014; Franck et al., 2017; Katan and Luft, 2018).”
Background
A neuroendoscopic navigation system based on dual-mode augmented reality for minimally invasive surgical treatment of hypertensive intracerebral hemorrhage
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Neutrophil-to-Lymphocyte Ratio as a Predictor of Short-Term Functional Outcomes in Acute Ischemic Stroke Patients
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“The global incidence of stroke has increased over the last few decades, with the most common subtype being ischemic stroke [2].”
Background
Biomaterials and Cell Therapy Combination in Central Nervous System Treatments
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“As one of the most prevalent neurological disorders, stroke remains a leading cause of disability and mortality worldwide, imposing a considerable burden on individuals, families, and healthcare systems [3,4].”
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“Patients were eligible if they fulfilled the following criteria: (1) absence of previous relevant disability evaluated by the modified Rankin Scale (mRS) score ≤2; (2) patients with an AIS affecting the proximal anterior cerebral circulation considered eligible for EVT.”
Method
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Background
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Background
Ring Finger Protein 146-mediated Long-chain Fatty-acid-Coenzyme a Ligase 4 Ubiquitination Regulates Ferroptosis-induced Neuronal Damage in Ischemic Stroke
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“high in middle- and low-income countries [3].”
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“We aim (1) to evaluate the aPL prevalence in ischemic stroke patients, (2) to”
BackgroundInfluential
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“075 Carotid ultrasound Plaque score median (IQR) 2 (1-4) 2 (1-3) 3 (2-4) <.”
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Therapeutic Effects of Resveratrol on Ischemia–Reperfusion Injury in the Nervous System
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Interpretable CNN for ischemic stroke subtype classification with active model adaptation
Zhang, S., Wang, J., Pei, L., Liu, K., Gao, Y., Fang, H., Zhang, R., Zhao, L., Sun, S., Wu, J. W., et al. (2022) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-021-01721-5 · Cited by 22
“The burden of stroke is rapidly increasing worldwide [1, 2].”
Background
Role of Mitophagy in the Pathogenesis of Stroke: From Mechanism to Therapy
Zhong, W.-J., Yang, X., Zhou, H., Xie, B.-R., Liu, W., & Li, Y. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/6232902 · Cited by 25
“Stroke is an acute cerebrovascular event that is one of the leading causes of death worldwide and a leading cause of adult disability [1].”
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Moreno‐Segura, N., Agustín, R. M., García-Bafalluy, S., & Escriche-Escuder, A. (2022) · Clinical Rehabilitation · doi:10.1177/02692155221117220 · Cited by 22
“Although mortality has dropped in developed countries, thanks to improvements in primary and secondary prevention, in the approach to acute stroke and subsequent neurorehabilitation, it is still responsible for high morbidity and long-term disability.(1,2) It is, therefore, a challenge for medical societies and health…”
Background
An overview of hyperbaric oxygen preconditioning against ischemic stroke
Wu, X., You, J., Chen, X., Zhou, M., Ma, H., Zhang, T., & Huang, C. (2023) · Metabolic Brain Disease · doi:10.1007/s11011-023-01165-y · Cited by 25
“Growing evidence from developed countries suggests that prevention should be given high priority to reduce the burden of stroke (Katan and Luft 2018).”
Background
Identification of serum exosomal metabolomic and proteomic profiles for remote ischemic preconditioning
Du, Y., Qiu, R., Chen, L., Chen, Y., Zhong, Z., Li, P., Fan, F., & Cheng, Y. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04070-1 · Cited by 23
“It is the main cause of global disability, with 50% of survivors suffering from chronic disability [4, 5].”
Background
Identification of cell death-related biomarkers and immune infiltration in ischemic stroke between male and female patients
Chen, W. K., Chen, Y., Wu, L., Gao, Y., Zhu, H., Ye, L., Ji, X., Wang, Z., Wang, W., Han, L., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1164742 · Cited by 22
“Inclusion criteria were as follows (1): the database contains the IS patient group and healthy control group”
Background
Malondialdehyde (MDA) and 8-hydroxy-2′-deoxyguanosine (8-OHdG) in ischemic stroke: a systematic review
Tugasworo, D., Prasetyo, A., Kurnianto, A., Retnaningsih, R., Andhitara, Y., Ardhini, R., & Budiman, J. (2023) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-023-00688-6 · Cited by 26
Using experience-based co-design to develop mobile/tablet applications to support a person-centred and empowering stroke rehabilitation
Marwaa, M. N., Guidetti, S. G. E., Ytterberg, C., & Kristensen, H. K. (2023) · Research Involvement and Engagement · doi:10.1186/s40900-023-00472-z · Cited by 26
“Introduction Stroke is recognized as a major cause of disability worldwide [1] and is often associated with long-term physical, cognitive, social and emotional disabilities [2–4], that can result in dependence and reduced participation in everyday life [3, 5, 6].”
Background
Serum Kynurenines Correlate With Depressive Symptoms and Disability in Poststroke Patients: A Cross-sectional Study
Carrillo‐Mora, P., de la Cruz, V. P., Estrada-Cortés, B., Toussaint-González, P., Martínez-Cortéz, J. A., Rodríguez-Barragán, M. A., Quinzaños-Fresnedo, J., Rangel-Caballero, F., Gamboa-Coria, G., Sánchez-Vázquez, I., et al. (2020) · Neurorehabilitation and neural repair · doi:10.1177/1545968320953671 · Cited by 23
“Adult patients (>18 years) was recruited of any sex that met the following inclusion criteria: (1) first event of ischemic or hemorrhagic stroke corroborated by neuroimaging study, (2) no history of previous neurological or psychiatric diseases, (3) evolution time of the stroke of >1 month, but <1 year, (4) that could…”
Method
Nanoarchitectonics of tannic acid based injectable hydrogel regulate the microglial phenotype to enhance neuroplasticity for poststroke rehabilitation
Liu, Z., Zhang, S., Ran, Y., Geng, H., Gao, F., Tian, G., Feng, Z., Xi, J., Ye, L., & Su, W. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00444-0 · Cited by 21
The transitional care from hospital to home for stroke survivors and their caregivers: A systematic review
Veronese, M., Vellone, E., Alvaro, R., & Pucciarelli, G. (2025) · Journal of Vascular Nursing · doi:10.1016/j.jvn.2025.03.002 · Cited by 21
The Functional Tactile Object Recognition Test: A Unidimensional Measure With Excellent Internal Consistency for Haptic Sensing of Real Objects After Stroke
Carey, L. M., Mak-Yuen, Y. Y. K., & Matyas, T. A. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.542590 · Cited by 22
“, 2003), although the burden of stroke in people younger than 65 years has increased over the last few decades (Katan and Luft, 2018).”
Background
Economic Burden of Stroke in Iran: A Population-Based Study.
Movahed, M., Barghazan, S. H., Adel, A., & Rezapour, A. (2021) · Value in Health Regional Issues · doi:10.1016/j.vhri.2020.04.004 · Cited by 21
Effects of argatroban therapy for stroke patients: A meta-analysis
Hou, X., Jin, C., Pan, C., Wang, X., Xue, J., Yang, Z., & Qi, D. (2021) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2021.06.002 · Cited by 21
Use of Mobile/Tablet and Web-Based Applications to Support Rehabilitation After Stroke: A Scoping Review
Marwaa, M. N., Guidetti, S. G. E., Ytterberg, C., & Kristensen, H. K. (2022) · Journal of Rehabilitation Medicine · doi:10.2340/jrm.v54.452 · Cited by 26
Predicting 10-year stroke mortality: development and validation of a nomogram
Szlachetka, W. A., Pana, T. A., Mamas, M. A., Bettencourt‐Silva, J. H., Metcalf, A. K., Potter, J. F., McLernon, D. J., & Myint, P. K. (2021) · Acta Neurologica Belgica · doi:10.1007/s13760-021-01752-9 · Cited by 21
A scoping review on studies about the quality of life of informal caregivers of stroke survivors
Moura, A., Teixeira, F., Amorim, M., Henriques, A., Nogueira, C., & Alves, E. (2021) · Quality of Life Research · doi:10.1007/s11136-021-02988-x · Cited by 21
Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies
Armstrong, N. D., Srinivasasainagendra, V., Patki, A., Tanner, R. M., Hidalgo, B., Tiwari, H. K., Limdi, N. A., Lange, E. M., Lange, L. A., Arnett, D. K., et al. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.781451 · Cited by 24
Noninvasive Pressure Estimation Based on the Subharmonic Response of SonoVue: Application to Intracranial Blood Pressure Assessment
Qiao, X., Wen, Y. M., Yu, J., Bouakaz, A., Zong, Y., & Wan, M. (2021) · IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control · doi:10.1109/tuffc.2021.3138100 · Cited by 21
Determinants of disability at 6 months after stroke: The GRECogVASC Study
Tasseel‐Ponche, S., Barbay, M., Roussel, M., Lamrani, A., Sader, T., Arnoux, A., Canaple, S., Lamy, C., Leclercq, C., Aarabi, A., et al. (2022) · European Journal of Neurology · doi:10.1111/ene.15319 · Cited by 21
Effects of Long‐Term Vagus Nerve Electrical Stimulation Therapy on Acute Cerebral Infarction and Neurological Function Recovery in Post MCAO Mice
Du, L., Yang, Z., Sheng, H., Liu, M., & Sun, Q. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/8131391 · Cited by 21
“Meanwhile, as the proportion of unhealthy eating habits increases, the proportion of young people su ﬀ ering from stroke is also increasing [2].”
A Systematic Review and Meta-Analysis of Serum Concentrations of Ischaemia-Modified Albumin in Acute Ischaemic Stroke, Intracerebral Haemorrhage, and Subarachnoid Haemorrhage
Mangoni, A. A., & Zinellu, A. (2022) · Biomolecules · doi:10.3390/biom12050653 · Cited by 20
“Despite significant advances in diagnosis and management, stroke remains the second leading cause of mortality and disability globally, and accounts for 3–7% of the total healthcare costs in developed countries with an estimated cost per person of USD 140,048 [3,4].”
Background
Plasma levels of BDNF and EGF are reduced in acute stroke patients
Øverberg, L. T., Lugg, E. F., Gaarder, M., Langhammer, B., Thommessen, B., Rønning, O. M., & Morland, C. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09661 · Cited by 23
“Stroke is the second leading cause of death and a major contributor to acquired disability in the world today [1].”
Background
Exploring the ability of stroke survivors in using the contralesional hemisphere to control a brain–computer interface
Mansour, S., Giles, J., Ang, K. K., Nair, K. P. S., Phua, K. S., & Arvaneh, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-20345-x · Cited by 22
“Participants were assessed for eligibility based on the following inclusion criteria: (1) Participants had their first cortical and sub-cortical stroke, with a Fugl-Meyer score ranging from mild to severe impairment of upper extremity function.”
Method
Tetramethylpyrazine alleviates mitochondrial abnormality in models of cerebral ischemia and oxygen/glucose deprivation Reoxygenation
Chang, C.-Y., Wu, C.-C., Pan, P., Wang, Y., Lin, S., Liao, S., Chen, W., Kuan, Y., & Chen, C. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114468 · Cited by 21
Current Biomarkers for Carotid Artery Stenosis: A Comprehensive Review of the Literature
Khan, H., Shaikh, F., Syed, M. H., Mamdani, M., Saposnik, G., & Qadura, M. (2023) · Metabolites · doi:10.3390/metabo13080919 · Cited by 21
“CAS can cause transient ischemic attacks (TIA) and cerebrovascular attacks (CVA), which are known to be the second most common cause of death and a major cause of disability worldwide [177].”
Background
A retrospective study on machine learning-assisted stroke recognition for medical helpline calls
Wenstrup, J., Havtorn, J. D., Borgholt, L., Blomberg, S. N. F., Maaløe, L., Sayre, M. R., Christensen, H., Kruuse, C. R., & Christensen, H. C. (2023) · npj Digital Medicine · doi:10.1038/s41746-023-00980-y · Cited by 24
L-Lactate Treatment at 24 h and 48 h after Acute Experimental Stroke Is Neuroprotective via Activation of the L-Lactate Receptor HCA1
Geiseler, S. J., Hadzic, A., Lambertus, M., Forbord, K. M., Sajedi, G., Liesz, A., & Morland, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021232 · Cited by 20
“Cerebral stroke is the second leading cause of death worldwide [1] and one of the most prevalent causes of long-term disabilities [2].”
Background
Hyperdense middle cerebral artery sign and response to combination of mechanical Thrombectomy plus intravenous thrombolysis in acute stroke patients
Mowla, A., Razavi, S., Lail, N. S., Mohammadi, P., Shirani, P., Kavak, K. S., Sawyer, R. N., & Kamal, H. (2021) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2021.117618 · Cited by 21
Upper-extremity motor recovery after stroke: A systematic review and meta-analysis of usual care in trials and observational studies
Kolmos, M., Munoz-Novoa, M., Sunnerhagen, K. S., Murphy, M. A., & Kruuse, C. R. (2024) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2024.123341 · Cited by 21
Stroke-related factors associated with gait asymmetry in ambulatory stroke survivors: A systematic review and meta-analysis
Xu, J., Witchalls, J. B., Preston, E., Li, P., Waddington, G. S., Adams, R. D., & Han, J. (2025) · Gait & Posture · doi:10.1016/j.gaitpost.2025.05.010 · Cited by 20
Valproate improves middle cerebral artery occlusion-induced ischemic cerebral disorders in mice and oxygen-glucose deprivation-induced injuries in microglia by modulating RMRP/PI3K/Akt axis
Li, X., & Sui, Y. (2020) · Brain Research · doi:10.1016/j.brainres.2020.147039 · Cited by 20
Pathogenic role of microRNAs in atherosclerotic ischemic stroke: Implications for diagnosis and therapy
Jiang, Q., Li, Y., Wu, Q., Huang, L., Xu, J., & Zeng, Q. (2021) · Genes & Diseases · doi:10.1016/j.gendis.2021.01.001 · Cited by 21
Designing an app for home-based enriched Music-supported Therapy in the rehabilitation of patients with chronic stroke: a pilot feasibility study
Segura, E., Grau‐Sánchez, J., David Sanchez-pinsach, B., Puebla, M. D. L. C., Duarte, E., Arcos, J. L., & Rodríguez‐Fornells, A. (2021) · Brain Injury · doi:10.1080/02699052.2021.1975819 · Cited by 20
“Stroke is the leading cause of acquired long-term disability worldwide (1).”
Background
Increased admission serum total bile acids can be associated with decreased 3-month mortality in patients with acute ischemic stroke
Huang, L., Xu, G., Zhang, R., Wang, Y., Ji, J., Long, F., & Sun, Y. (2022) · Lipids in Health and Disease · doi:10.1186/s12944-021-01620-8 · Cited by 20
“2] of the total deaths in 2019) worldwide after ischemic heart disease [1] and is also associated with a high rate of disability and recurrence, which brings a great burden to society and families, especially in low- and middle-income countries [1, 2].”
Background
Enhanced Rehabilitation Outcomes of Robotic-Assisted Gait Training with EksoNR Lower Extremity Exoskeleton in 19 Stroke Patients
Wiśniowska-Szurlej, A., Wołoszyn, N., Brożonowicz, J., Ciąpała, G., Pietryka, K., Grzegorczyk, J., Leszczak, J., Ćwirlej-Sozańska, A. B., Sozański, B., & Korczowski, B. (2023) · Medical Science Monitor · doi:10.12659/msm.940511 · Cited by 24
Occupational Risk Factors for Stroke: A Comprehensive Review
Yang, M., Yoo, H., Kim, S., Kwon, O., Nam, M.-W., Pan, K. H., & Kang, M. (2023) · Journal of Stroke · doi:10.5853/jos.2023.01011 · Cited by 22
The efficacy and safety of interleukin-1 receptor antagonist in stroke patients: A systematic review
Kazmi, S., Salehi‐Pourmehr, H., Sadigh‐Eteghad, S., & Farhoudi, M. (2024) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2024.01.009 · Cited by 20
Long non-coding RNA RMST promotes oxygen-glucose deprivation-induced injury in brain microvascular endothelial cells by regulating miR-204-5p/VCAM1 axis
Dongliang, Y., Xu, F., Lü, M., & Li, X. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119244 · Cited by 20
Electrophysiological Correlates of Virtual-Reality Applications in the Rehabilitation Setting: New Perspectives for Stroke Patients
Arcuri, F., Porcaro, C., Ciancarelli, I., Tonin, P., & Cerasa, A. (2021) · Electronics · doi:10.3390/electronics10070836 · Cited by 20
“This approach ensures the improvement of quality of life (QOF) and the performance of ADL [5].”
BackgroundInfluential
Advancing Cardiovascular Health Equity Globally Through Digital Technologies
Ogungbe, O., Longenecker, C. T., Beaton, A., de Loizaga, S. R., Brant, L. C. C., Turkson‐Ocran, R., Bastani, P. B., Sarfo, F. S., & Commodore-Mensah, Y. Y. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.031237 · Cited by 21
“27 The burden of stroke globally is unevenly distributed.”
Background
Post-stroke dizziness, depression and anxiety
Gu, P., Ding, Y., Mangal, R., Feng, J., Fan, H., Fayyaz, A., & Geng, X. (2024) · Neurological Research · doi:10.1080/01616412.2024.2328490 · Cited by 24
“Stroke caused by cerebral infarction or cerebral hemorrhage is a major cause of disability and the second leading cause of death worldwide [32].”
Background
Machine learning–based predictive model for post-stroke dementia
Wei, Z., Li, M., Zhang, C., Miao, J., Wang, W., & Fan, H. W. (2024) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-024-02752-4 · Cited by 19
“It is characterized by a high incidence rate, elevated mortality, and increased disability rates [1].”
Background
Health literacy in stroke disease: A systematic review
Ymeraj, M., Kotica, F., Bozzolan, G., Rocco, G., Virgolesi, M., Alvaro, R., Vellone, E., & Pucciarelli, G. (2025) · Journal of Vascular Nursing · doi:10.1016/j.jvn.2025.01.001 · Cited by 19
Clinical pattern and predictors of stroke treatment outcome among hospitalised patients who had a stroke at Felege Hiwot comprehensive specialised hospital, northwest Ethiopia: a retrospective cross-sectional study
Kefale, B., Ewunetei, A., Molla, M., Tegegne, G. T., & Degu, A. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-040238 · Cited by 20
Physical activity and stroke among women – A non-linear relationship
MacDonald, C. J., Madika, A., Gomes, R., Severi, G., Sibon, I., Debette, S., & Boutron‐Ruault, M. (2021) · Preventive Medicine · doi:10.1016/j.ypmed.2021.106485 · Cited by 19
Effect of RehaCom cognitive rehabilitation software on working memory and processing speed in chronic ischemic stroke patients
Amiri, S., Hassani‐Abharian, P., Vaseghi, S., Kazemi, R., & Nasehi, M. M. (2021) · Assistive Technology · doi:10.1080/10400435.2021.1934608 · Cited by 19
The everyday life situation of caregivers to family members who have had a stroke and received the rehabilitation intervention F@ce in Uganda
Eriksson, G. M., Kamwesiga, J. T., & Guidetti, S. G. E. (2021) · Archives of Public Health · doi:10.1186/s13690-021-00618-z · Cited by 19
Seasonal Variation in Incidence of Stroke in a General Population of 1.4 Million Japanese: The Shiga Stroke Registry
Fujii, T., Arima, H., Takashima, N., Kita, Y., Miyamatsu, N., Tanaka‐Mizuno, S., Shitara, S., Urushitani, M., Miura, K., & Nozaki, K. (2021) · Cerebrovascular Diseases · doi:10.1159/000518370 · Cited by 19
Factors associated with sustaining work after an acquired brain injury: a scoping review
Karcz, K., Trezzini, B., Escorpizo, R. S., Schwegler, U., & Finger, M. E. (2021) · Disability and Rehabilitation · doi:10.1080/09638288.2021.1960439 · Cited by 19
Updated evidence of Dengzhan Shengmai capsule against ischemic stroke: A systematic review and meta-analysis
Liu, X., Yi-qi, L., Bai, N., Yu, C., Xiao, Y., Li, C., & Liu, Z. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114675 · Cited by 19
LncRNA CASC15 Promotes Cerebral Ischemia/Reperfusion Injury via miR-338-3p/ETS1 Axis in Acute Ischemic Stroke
Chen, C., Wang, L., Wang, L., Liu, Q., & Wang, C. (2021) · International Journal of General Medicine · doi:10.2147/ijgm.s323237 · Cited by 19
Factors Associated with Knowledge and Awareness of Stroke Among the Jordanian Population: A Cross-Sectional Study
Barakat, M. M., ALSalamat, H., Jirjees, F., Al-Obaidi, H. J., Hussain, Z. K., Hadidi, S. E., Mansour, S., Malaeb, D. N., & Hosseini, H. (2022) · F1000Research · doi:10.12688/f1000research.74492.2 · Cited by 19
Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation
Zhan, L., Chen, M., Pang, T., Li, X., Long, L., Liang, D., Peng, L., Sun, W., & Xu, E. (2022) · Brain Pathology · doi:10.1111/bpa.13109 · Cited by 19
“Stroke is the second leading cause of mortality and a major cause of long-term disability worldwide [1, 2], with ischemic stroke accounting for at least 80% of all strokes.”
Background
Somatosensory Impairment and Chronic Pain Following Stroke: An Observational Study
Haslam, B. S., Butler, D. S., Kim, A., & Carey, L. M. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20020906 · Cited by 19
“Following heart disease, a stroke is the most common cause of death and a leading cause of disability [1,2].”
BackgroundInfluential
Twenty-eight-day in-hospital mortality prediction for elderly patients with ischemic stroke in the intensive care unit: Interpretable machine learning models
Huang, J., Jin, W., Duan, X., Liu, X., Shu, T., Fu, L., Deng, J., Chen, H., Liu, G., Jiang, Y., et al. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2022.1086339 · Cited by 19
“The inclusion criteria for the present study were as follows: (1) first-ever ICU admission and (2) age ≥ 65 years.”
BackgroundMethodInfluential
Digital Health Behavioural Interventions to Support Physical Activity and Sedentary Behaviour in Adults after Stroke: A Systematic Literature Review with Meta-Analysis of Controlled Trials
Wang, S., & Kassavou, A. (2023) · Behavioral Sciences · doi:10.3390/bs13010062 · Cited by 18
“With an increasingly ageing population worldwide, stroke has become a leading cause of death and a major cause of disability, annually impacting 15 million people globally [1,2].”
Background
Inhibition of Vesicular Glutamate Transporters (VGLUTs) with Chicago Sky Blue 6B Before Focal Cerebral Ischemia Offers Neuroprotection
Pomierny, B., Krzyżanowska, W., Skórkowska, A., Jurczyk, J., Bystrowska, B., Budziszewska, B., & Pera, J. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03259-1 · Cited by 18
Limitations in utilization and prioritization of standardized somatosensory assessments after stroke: A cross-sectional survey of neurorehabilitation clinicians
Hoh, J. E., Borich, M. R., Kesar, T. M., Reisman, D. S., & Semrau, J. A. (2023) · Topics in Stroke Rehabilitation · doi:10.1080/10749357.2023.2200304 · Cited by 19

Authors: Katan, M., & Luft, A.
Affiliations: Department of Neurology, Stroke Center, University Hospital of Zurich, Zurich, Switzerland
University Hospital Zurich (CH)
Corresponding author: Luft, Andreas
ORCID: Luft, Andreas
Venue: Seminars in Neurology
Publisher: Georg Thieme Verlag KG
Published: 2018-04
Volume: 38
Issue: 02
Pages: 208-211
ISSN: 0271-8235 (ISSN-L)
1098-9021
DOI: 10.1055/s-0038-1649503
OpenAlex: W2803306216
Cited by: 2,137
References: 57
Citations by year: 2026: 164 · 2025: 350 · 2024: 361 · 2023: 387 · 2022: 376 · 2021: 276 · 2020: 159 · 2019: 55 · 2018: 7
FWCI: 17.75
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Seminars in Neurology (publishedVersion)
PubMed (publishedVersion)
Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
Zurich Open Repository and Archive (University of Zurich)
Topics: Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
Keywords: stroke, global burden of disease, stroke incidence, stroke mortality, ischemic stroke, hemorrhagic stroke, disability-adjusted life years, population aging, young adults, low- and middle-income countries, ethnic disparities, stroke prevention, neurorehabilitation
MeSH terms: Humans, Sex Factors, Global Health, Disease Management, Stroke

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