The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Generalized Anxiety Disorder
Abstract
Persistent anxiety and uncontrollable worry for at least 6 months characterize generalized anxiety disorder. First-line treatments are cognitive behavioral therapy or pharmacotherapy with a selective serotonin-reuptake or serotonin–norepinephrine reuptake inhibitor.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Instead, Western frameworks classify anxiety as a discrete clinical disorder based on neurochemical and cognitive dysfunction, with treatment through psychotherapeutic or pharmacological interventions [18,19].”
From Voices of the Pacific: Pacific Peoples’ Conceptualisations of Anxiety in Aotearoa New Zealand—Findings from a Cross-Sectional Survey (2026) · cites this paper as [18]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7
Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765
Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection
Kroenke, K., Spitzer, R. L., Williams, J. B. W., Monahan, P. O., & Löwe, B. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-5-200703060-00004 · Cited by 4,741
The effect of mindfulness based therapy on anxiety and depression: A meta analytic review
Hofmann, S. G., Sawyer, A. T., Witt, A. A., & Oh, D. (2010) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0018555 · Cited by 3,846
Katzman, M. A., Bleau, P., Blier, P., Chokka, P., Kjernisted, K., Van Ameringen, M., & the Canadian Anxiety Guidelines Initiative Group on behalf of the Anxiety Disorders Association of Canada/Association Canadienne des troubles anxieux and McGill University (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-s1-s1 · Cited by 1,090
The Descriptive Epidemiology of Commonly Occurring Mental Disorders in the United States
Kessler, R. C., & Wang, P. S. (2008) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.29.020907.090847 · Cited by 888
McHugh, R. K., Whitton, S. W., Peckham, A. D., Welge, J. A., & Otto, M. W. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12r07757 · Cited by 800
Psychological treatment of generalized anxiety disorder: A meta-analysis
Cuijpers, P., Sijbrandij, M., Koole, S., Huibers, M., Berking, M., & Andersson, G. (2014) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.01.002 · Cited by 527
Roy-Byrne, P., Craske, M. G., Sullivan, G., Rose, R. D., Edlund, M. J., Lang, A. J., Bystritsky, A., Welch, S. S., Chavira, D. A., Golinelli, D., et al. (2010) · JAMA · doi:10.1001/jama.2010.608 · Cited by 452
Self-citationBandelow, B., Sher, L., Bunevicius, R., Hollander, E., Kasper, S., Zohar, J., Möller, H.-J., WFSBP Task Force on Mental Disorders in Primary Care, & WFSBP Task Force on Anxiety Disorders, O. A. P. (2012) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651501.2012.667114 · Cited by 428
Research works printed but not linked: 29
- 10.1097/JGP.0b013e318202bc62 · DOI
- 10.1097/01.mlr.0000185750.18119.fd · DOI
- 10.1001/archpediatrics.2010.170 · DOI · Paper page
- 10.1002/da.22026 · DOI
- 10.1016/j.jad.2014.06.021 · DOI
- 10.1001/archpsyc.62.2.182 · DOI
- Hettema JM, 2015, Psychol Med
- 10.1016/j.cpr.2011.05.001 · DOI · Paper page
- 10.1016/S2215-0366(14)70305-0 · DOI
- 10.1016/j.jad.2014.01.022 · DOI
- 10.1192/bjp.bp.114.149880 · DOI · Paper page
- 10.1016/j.jad.2014.07.031 · DOI
- 10.1517/14656566.2015.1059424 · DOI
- Bereza BG, 2012, Can J Psychiatry, 57, 470, 10.1177/070674371205700805 · DOI
- 10.1007/s40263-014-0217-8 · DOI
- Ravindran LN, Stein MB. Anxiety disorders: somatic treatment. In: Sadock BJ, Sadock VA, Ruiz P, eds. Kaplan & Sadock comprehensive textbook of psychiatry. 9th ed. Philadelphia: Lippincott Williams & Wilkins, 2009:1906-1914.
- Kapczinski F, 2003, Cochrane Database Syst Rev, CD003592
- 10.1056/NEJMcp1402180 · DOI
- 10.1002/da.22365 · DOI
- 10.1002/hup.2371 · DOI
- Chessick CA, 2006, Cochrane Database Syst Rev, CD006115
- 10.1177/0269881115598411 · DOI
- 10.1002/phar.1529 · DOI
- Guaiana G, 2010, Cochrane Database Syst Rev, CD006815
- 10.1001/jamapsychiatry.2015.0351 · DOI · Paper page
- 10.1517/14740338.2015.1014796 · DOI
- 10.1001/jamapsychiatry.2015.1154 · DOI
- 10.1176/appi.ajp.2014.13101337 · DOI
- 10.1176/appi.ajp.2013.12081104 · DOI
Cited by
Sorted by citations
Comorbidity of anxiety and depression in children and adolescents: 20 years after
Cummings, C. M., Caporino, N. E., & Kendall, P. C. (2014) · Psychological Bulletin · doi:10.1037/a0034733 · Cited by 1,028
Dhir, A., Yossatorn, Y., Kaur, P., & Chen, S. (2018) · International Journal of Information Management · doi:10.1016/j.ijinfomgt.2018.01.012 · Cited by 1,033
Craske, M. G., & Stein, M. B. (2016) · The Lancet · doi:10.1016/s0140-6736(16)30381-6 · Cited by 640
Self-citationJacobson, N. C., & Newman, M. G. (2017) · Psychological Bulletin · doi:10.1037/bul0000111 · Cited by 576
Mossman, S. A., Luft, M. J., Schroeder, H. K., Varney, S. T., Fleck, D. E., Barzman, D. H., Gilman, R., DelBello, M. P., & Strawn, J. R. (2017) · Annals of Clinical Psychiatry · doi:10.1177/104012371702900404 · Cited by 471
García-Gutiérrez, M. S., Navarrete, F., Gasparyan, A., Austrich-Olivares, A., Sala, F., & Manzanares, J. (2020) · Biomolecules · doi:10.3390/biom10111575 · Cited by 306
Neuropsychiatric sequelae of stroke
Ferro, J. M., Caeiro, L., & Figueira, M. L. (2016) · Nature Reviews Neurology · doi:10.1038/nrneurol.2016.46 · Cited by 237
Strawn, J. R., Geracioti, L., Rajdev, N., Clemenza, K., & Levine, A. (2018) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2018.1491966 · Cited by 214
Anxiety After Stroke: The Importance of Subtyping
Chun, H.-Y. Y., Whiteley, W. N., Dennis, M. S., Mead, G. E., & Carson, A. J. (2018) · Stroke · doi:10.1161/strokeaha.117.020078 · Cited by 172
Optogenetic insights on the relationship between anxiety-related behaviors and social deficits
Allsop, S. A., Vander Weele, C. M., Wichmann, R., & Tye, K. M. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00241 · Cited by 150
Richards, D., Richardson, T., Timulak, L., & McElvaney, J. (2015) · Internet Interventions · doi:10.1016/j.invent.2015.07.003 · Cited by 111
Growth factors as clinical biomarkers of prognosis and diagnosis in psychiatric disorders
Galvez-Contreras, A. Y., Campos-Ordonez, T., Lopez-Virgen, V., Gomez-Plascencia, J., Ramos-Zuniga, R., & Gonzalez-Perez, O. (2016) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2016.08.004 · Cited by 112
Nordahl, H. M., Borkovec, T. D., Hagen, R., Kennair, L. E. O., Hjemdal, O., Solem, S., Hansen, B., Haseth, S., & Wells, A. (2018) · BJPsych Open · doi:10.1192/bjo.2018.54 · Cited by 102
Lehrer, P. M. (2018) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2017.09.012 · Cited by 73
A randomized controlled trial of medication and cognitive-behavioral therapy for hypochondriasis
Fallon, B. A., Ahern, D. K., Pavlicova, M., Slavov, I., Skritskya, N., & Barsky, A. J. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.16020189 · Cited by 65
Agomelatine for the treatment of generalized anxiety disorder
Buoli, M., Grassi, S., Serati, M., & Altamura, A. C. (2017) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2017.1359257 · Cited by 61
Attentional control and suppressing negative thought intrusions in pathological worry
Fox, E., Dutton, K., Yates, A., Georgiou, G. A., & Mouchlianitis, E. (2015) · Clinical Psychological Science · doi:10.1177/2167702615575878 · Cited by 57
Wells, A. C., & Lotfipour, S. (2023) · Advances in Drug and Alcohol Research · doi:10.3389/adar.2023.11628 · Cited by 50
Teng, M.-H., Hou, Y.-M., Chang, S.-H., & Cheng, H.-J. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.12.118 · Cited by 37
Testing the habituation-based model of exposures for child and adolescent anxiety
Peterman, J. S., Carper, M. M., & Kendall, P. C. (2019) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2016.1163707 · Cited by 39
Update on treatments for anxiety-related disorders
Lee, H. J., & Stein, M. B. (2023) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000841 · Cited by 43
Self-citationTesting a procedural variant of written imaginal exposure for generalized anxiety disorder
Fracalanza, K., Koerner, N., & Antony, M. M. (2014) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2014.05.011 · Cited by 33
Ren, L., Yang, Z., Wang, Y., Cui, L.-B., Jin, Y., Ma, Z., Zhang, Q., Wu, Z., Wang, H.-N., & Yang, Q. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02849-w · Cited by 33
Anxiety Disorders in Late Life
Ramos, K., & Stanley, M. A. (2018) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2017.10.005 · Cited by 33
Kanuri, N., Taylor, C. B., Cohen, J. M., & Newman, M. G. (2015) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2015.05.011 · Cited by 32
Strawn, J. R., & Levine, A. (2020) · Biomarkers in Neuropsychiatry · doi:10.1016/j.bionps.2020.100024 · Cited by 30
Liu, H., Tian, Y., Liu, Y., Nigatu, Y. T., & Wang, J. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.01.007 · Cited by 23
Anxiety Disorders in Late Life
Ramos, K., & Stanley, M. A. (2020) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2019.11.005 · Cited by 20
Psychological inflexibility mediates the effects of self-efficacy and anxiety sensitivity on worry
Ruiz, F. J. (2014) · The Spanish Journal of Psychology · doi:10.1017/sjp.2014.3 · Cited by 18
Umeh, G. C., & Bangirana, P. (2016) · Tanzania Journal of Health Research · doi:10.4314/thrb.v19i1.3 · Cited by 3
Zhang, B., Li, Y., Chu, W., Li, Y., Zhang, J., Lv, Z., Luo, Y., & Chen, Y. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1669888 · Cited by 3
Chandra, L. A., McLean-Orsborn, S., Tone-Graham, P. V., & Kapeli, S. A. (2026) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph23030291
Metadata
- Authors
- Stein, M. B., & Sareen, J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-11-19
- Volume
- 373
- Issue
- 21
- Pages
- 2059-2068
- ISSN
- 0028-4793
- 1533-4406
- Cited by
- 314
- References
- 23
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
