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Cell Death
Open accessAbstract
This review is a primer on the three main mechanisms of cell death: apoptosis, autophagy-associated cell death, and necrosis. The authors discuss the clinical implications of each of these types of cell death and indicate where advances in our understanding have inspired new forms of therapy.
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Cites
Apoptosis in the Pathogenesis and Treatment of Disease
Thompson, C. B. (1995) · Science · doi:10.1126/science.7878464 · Cited by 6,524
Danial, N. N., & Korsmeyer, S. J. (2004) · Cell · doi:10.1016/s0092-8674(04)00046-7 · Cited by 4,651
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., El-Deiry, W. S., Golstein, P., Green, D. R., et al. (2009) · Cell Death & Differentiation · doi:10.1038/cdd.2008.150 · Cited by 3,399
Ravikumar, B., Vacher, C., Berger, Z., Davies, J. E., Luo, S., Oroz, L. G., Scaravilli, F., Easton, D. F., Duden, R., O'Kane, C. J., et al. (2004) · Nature Genetics · doi:10.1038/ng1362 · Cited by 2,347
p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa
Villunger, A., Michalak, E. M., Coultas, L., Müllauer, F., Böck, G., Ausserlechner, M. J., Adams, J. M., & Strasser, A. (2003) · Science · doi:10.1126/science.1090072 · Cited by 1,327
Self-citationBCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.
Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M., & Korsmeyer, S. J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.6961 · Cited by 1,252
Kuwana, T., Bouchier-Hayes, L., Chipuk, J. E., Bonzon, C., Sullivan, B. A., Green, D. R., & Newmeyer, D. D. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.02.003 · Cited by 1,185
Regulation of autophagy by cytoplasmic p53
Tasdemir, E., Maiuri, M. C., Galluzzi, L., Vitale, I., Djavaheri-Mergny, M., D'Amelio, M., Criollo, A., Morselli, E., Zhu, C., Harper, F., et al. (2008) · Nature Cell Biology · doi:10.1038/ncb1730 · Cited by 1,132
Cell death by necrosis: towards a molecular definition
Golstein, P., & Kroemer, G. (2007) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.11.001 · Cited by 1,044
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
Kim, H., Rafiuddin-Shah, M., Tu, H.-C., Jeffers, J. R., Zambetti, G. P., Hsieh, J. J.-D., & Cheng, E. H.-Y. (2006) · Nature Cell Biology · doi:10.1038/ncb1499 · Cited by 874
Research works printed but not linked: 109
- 10.1038/35083653 · DOI
- 10.1016/j.coi.2007.05.004 · DOI · Paper page
- Majno G, 1995, Am J Pathol, 146, 3
- 10.1146/annurev.immunol.21.120601.141029 · DOI · Paper page
- 10.1172/JCI26321 · DOI
- 10.1016/j.molmed.2006.04.003 · DOI
- 10.1038/nrd2658 · DOI · Paper page
- 10.1038/nrm2245 · DOI · Paper page
- 10.1038/nrc1738 · DOI · Paper page
- 10.1038/nri2161 · DOI · Paper page
- 10.1038/ncb0608-637 · DOI
- 10.1172/JCI26274 · DOI
- 10.1101/gad.1376506 · DOI · Paper page
- 10.1016/j.bbabio.2006.06.014 · DOI · Paper page
- 10.1016/j.cell.2007.07.013 · DOI
- Laster SM, 1988, J Immunol, 141, 2629, 10.4049/jimmunol.141.8.2629 · DOI · Paper page
- 10.1038/bjc.1972.33 · DOI · Paper page
- 10.1038/nri1568 · DOI · Paper page
- 10.1038/nrm2308 · DOI · Paper page
- 10.1038/sj.cdd.4400877 · DOI
- 10.1002/hep.21062 · DOI · Paper page
- 10.1101/gad.1063703 · DOI · Paper page
- 10.1016/j.tcb.2008.06.002 · DOI
- 10.1053/j.gastro.2005.06.006 · DOI
- 10.1016/j.immuni.2007.12.017 · DOI · Paper page
- 10.1016/j.cell.2005.05.019 · DOI · Paper page
- 10.1093/emboj/17.3.706 · DOI · Paper page
- 10.1038/onc.2008.299 · DOI
- 10.1016/S0092-8674(00)80434-1 · DOI · Paper page
- 10.1016/S0092-8674(00)00008-8 · DOI · Paper page
- 10.1016/j.cell.2007.10.042 · DOI
- 10.1038/sj.cdd.4401596 · DOI
- 10.1038/23730 · DOI · Paper page
- 10.2337/db07-1692 · DOI
- 10.1016/j.cell.2007.03.017 · DOI
- 10.1101/gad.897601 · DOI · Paper page
- 10.1126/science.1133289 · DOI · Paper page
- 10.1016/j.tcb.2008.01.007 · DOI · Paper page
- 10.1016/j.molcel.2004.12.030 · DOI · Paper page
- 10.1126/science.286.5445.1735 · DOI · Paper page
- 10.1016/S1535-6108(03)00244-7 · DOI · Paper page
- 10.1182/blood-2005-04-1595 · DOI · Paper page
- 10.1038/335440a0 · DOI · Paper page
- 10.1038/348331a0 · DOI · Paper page
- 10.1038/nrd2656 · DOI · Paper page
- 10.1073/pnas.0606176103 · DOI · Paper page
- 10.1200/JCO.2008.17.2064 · DOI
- 10.1007/s10875-007-9161-4 · doi:10.1007/s10875-007-9161-4
- 10.1002/9780470697405.ch2 · DOI
- 10.1056/NEJMra041996 · DOI · Paper page
- 10.1126/science.287.5455.947 · doi:10.1126/science.287.5455.947
- 10.1126/science.287.5455.1056 · DOI · Paper page
- 10.1213/ane.0b013e31818cdb29 · DOI
- 10.1002/hep.21664 · DOI
- 10.1056/NEJMoa071142 · DOI · Paper page
- 10.1212/01.wnl.0000277487.04281.db · DOI · Paper page
- 10.1097/00003246-199907000-00002 · DOI · Paper page
- Hotchkiss RS, 2001, J Immunol, 166, 6952, 10.4049/jimmunol.166.11.6952 · DOI · Paper page
- 10.1097/00003246-200009000-00016 · DOI
- 10.1038/nri1943 · DOI · Paper page
- 10.2174/138161208784980617 · doi:10.2174/138161208784980617
- 10.1083/jcb.12.1.198 · DOI · Paper page
- 10.1038/labinvest.2009.8 · DOI
- 10.1172/JCI26185 · DOI · Paper page
- 10.1172/JCI26390 · DOI · Paper page
- 10.1039/b804606a · DOI
- 10.2174/157015908784533897 · DOI
- 10.1158/1078-0432.CCR-07-1595 · DOI · Paper page
- 10.1126/science.312.5777.1160 · DOI
- 10.1038/cdd.2008.131 · DOI · Paper page
- 10.1038/ncb1634 · DOI · Paper page
- 10.1111/j.1600-0463.2007.00858.x · DOI
- 10.1038/ncb1426 · DOI · Paper page
- 10.1084/jem.185.8.1481 · DOI · Paper page
- 10.1016/j.bcp.2008.07.041 · DOI · Paper page
- 10.1146/annurev.pharmtox.44.101802.121804 · DOI
- 10.1016/j.febslet.2007.05.038 · DOI
- 10.1084/jem.20072152 · DOI · Paper page
- 10.1091/mbc.01-05-0272 · DOI · Paper page
- 10.1038/nrd1718 · DOI · Paper page
- 10.2174/156652408784221306 · DOI · Paper page
- 10.1038/nri1594 · DOI · Paper page
- 10.1126/stke.2872005pe26 · DOI
- 10.1126/stke.3582006pe44 · DOI
- Sato T, 2008, J Immunol, 181, 197, 10.4049/jimmunol.181.1.197 · DOI
- 10.1038/ni914 · DOI
- 10.1093/hmg/ddl036 · DOI · Paper page
- 10.1128/MCB.25.3.1025-1040.2005 · DOI · Paper page
- 10.1172/JCI26322 · DOI · Paper page
- 10.1038/ncb1482 · DOI · Paper page
- 10.1128/MCB.02141-06 · DOI · Paper page
- 10.1172/JCI33700 · DOI · Paper page
- 10.1038/nrm2451 · DOI · Paper page
- 10.1016/j.bbrc.2006.12.098 · DOI
- 10.1016/j.it.2005.06.004 · DOI · Paper page
- 10.1615/CritRevImmunol.v23.i12.20 · DOI
- 10.1038/35003208 · DOI · Paper page
- 10.1073/pnas.1031788100 · DOI
- 10.1038/cdd.2008.100 · DOI
- 10.1146/annurev.med.59.061506.110403 · doi:10.1146/annurev.med.59.061506.110403
- 10.1016/S0733-8651(05)70198-3 · DOI
- 10.1158/1078-0432.CCR-07-0950 · DOI
- 10.1038/onc.2008.302 · DOI · Paper page
- 10.1016/j.coph.2008.06.016 · DOI · Paper page
- 10.1074/jbc.M503113200 · DOI
- 10.1016/j.neuroscience.2008.09.007 · DOI
- 10.1053/j.jvca.2008.02.011 · doi:10.1053/j.jvca.2008.02.011
- 10.1002/mus.21059 · DOI
- 10.1016/j.nurt.2008.10.030 · DOI
Cited by
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
Czabotar, P. E., Lessene, G., Strasser, A., & Adams, J. M. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3722 · Cited by 3,219
Self-citationMacrophages: master regulators of inflammation and fibrosis
Wynn, T., & Barron, L. (2010) · Seminars in Liver Disease · doi:10.1055/s-0030-1255354 · Cited by 1,392
Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging
Green, D. R., Galluzzi, L., & Kroemer, G. (2011) · Science · doi:10.1126/science.1201940 · Cited by 1,245
The immune system’s role in sepsis progression, resolution, and long-term outcome
Delano, M. J., & Ward, P. A. (2016) · Immunological Reviews · doi:10.1111/imr.12499 · Cited by 880
Pathophysiology of Sickle Cell Disease
Sundd, P., Gladwin, M. T., & Novelli, E. M. (2019) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-012418-012838 · Cited by 813
Metadata
- Authors
- Hotchkiss, R. S., Strasser, A., McDunn, J. E., & Swanson, P. E.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2009-10-15
- Volume
- 361
- Issue
- 16
- Pages
- 1570-1583
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W161836838
- Cited by
- 1,154
- References
- 16
- FWCI
- 29.41
- Type
- journal article
- Language
- en
- Open access
- green
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