Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state

Proteomic analysis of post-translational modifications

Mann, M., & Jensen, O. N. (2003) · Nature Biotechnology · doi:10.1038/nbt0303-255 · Cited by 2,136 · see citing works

Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process

Zubarev, R. A., Kelleher, N. L., & McLafferty, F. W. (1998) · Journal of the American Chemical Society · doi:10.1021/ja973478k · Cited by 1,881 · see citing works

The Management of Hypertrophic Cardiomyopathy

Spirito, P., Seidman, C. E., McKenna, W. J., & Maron, B. J. (1997) · New England Journal of Medicine · doi:10.1056/nejm199703133361107 · Cited by 1,026 · see citing works

Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations

Zubarev, R. A., Horn, D. M., Fridriksson, E. K., Kelleher, N. L., Kruger, N. A., Lewis, M. A., Carpenter, B. K., & McLafferty, F. W. (2000) · Analytical Chemistry · doi:10.1021/ac990811p · Cited by 986 · see citing works

Top Down versus Bottom Up Protein Characterization by Tandem High-Resolution Mass Spectrometry

Kelleher, N. L., Lin, H., Valaskovic, G. A., Aaserud, D. J., Fridriksson, E. K., & McLafferty, F. W. (1999) · Journal of the American Chemical Society · doi:10.1021/ja973655h · Cited by 606 · see citing works

The role of electron capture dissociation in biomolecular analysis

Cooper, H. J., Håkansson, K., & Marshall, A. G. (2004) · Mass Spectrometry Reviews · doi:10.1002/mas.20014 · Cited by 514 · see citing works

Decoding protein modifications using top-down mass spectrometry

Siuti, N., & Kelleher, N. L. (2007) · Nature Methods · doi:10.1038/nmeth1097 · Cited by 503 · see citing works

Precision proteomics: The case for high resolution and high mass accuracy

Mann, M., & Kelleher, N. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800788105 · Cited by 450 · see citing works

Mass Spectrometry: Bottom-Up or Top-Down?

Chait, B. T. (2006) · Science · doi:10.1126/science.1133987 · Cited by 442 · see citing works

Phosphorylation switches specific for the cardiac isoform of myosin binding protein‐C: a modulator of cardiac contraction?

Gautel, M., Zuffardi, O., Freiburg, A., & Labeit, S. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07187.x · Cited by 411 · see citing works

Localization of O-Glycosylation Sites in Peptides by Electron Capture Dissociation in a Fourier Transform Mass Spectrometer

Mirgorodskaya, E. E., Roepstorff, P., & Zubarev, R. A. (1999) · Analytical Chemistry · doi:10.1021/ac990578v · Cited by 382 · see citing works

Localization of Labile Posttranslational Modifications by Electron Capture Dissociation: The Case of γ-Carboxyglutamic Acid

Kelleher, N. L., Zubarev, R. A., Bush, K. A., Furie, B., Furie, B. C., McLafferty, F. W., & Walsh, C. T. (1999) · Analytical Chemistry · doi:10.1021/ac990684x · Cited by 367 · see citing works

Top Down Characterization of Larger Proteins (45 kDa) by Electron Capture Dissociation Mass Spectrometry

Ge, Y., Lawhorn, B. G., ElNaggar, M., Strauss, E., Park, J.-H., Begley, T. P., & McLafferty, F. W. (2002) · Journal of the American Chemical Society · doi:10.1021/ja011335z · Cited by 356 · see citing works

Extending Top-Down Mass Spectrometry to Proteins with Masses Greater Than 200 Kilodaltons

Han, X., Jin, M., Breuker, K., & McLafferty, F. W. (2006) · Science · doi:10.1126/science.1128868 · Cited by 328 · see citing works

Cardiac Myosin Binding Protein C

Flashman, E., Redwood, C. S., Moolman‐Smook, J. C., & Watkins, H. C. (2004) · Circulation Research · doi:10.1161/01.res.0000127175.21818.c2 · Cited by 323 · see citing works

A Molecular Map of the Interactions between Titin and Myosin‐Binding Protein C

Freiburg, A., & Gautel, M. (1996) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1996.00317.x · Cited by 281 · see citing works

Collisional Activation of Large Multiply Charged Ions Using Fourier Transform Mass Spectrometry

Senko, M. W., Speir, J. P., & McLafferty, F. W. (1994) · Analytical Chemistry · doi:10.1021/ac00090a003 · Cited by 263 · see citing works

Three-dimensional structure of vertebrate cardiac muscle myosin filaments

Zoghbi, M. E., Woodhead, J. L., Moss, R. L., & Craig, R. W. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708912105 · Cited by 259 · see citing works

Quantitative Analysis of Modified Proteins and Their Positional Isomers by Tandem Mass Spectrometry: Human Histone H4

Pesavento, J. J., Mizzen, C. A., & Kelleher, N. L. (2006) · Analytical Chemistry · doi:10.1021/ac0600050 · Cited by 240 · see citing works

Cardiac Myosin-Binding Protein-C Phosphorylation and Cardiac Function

Sadayappan, S., Gulick, J. M., Osińska, H. E., Martin, L. A., Hahn, H. S., Dorn, G. W., Klevitsky, R., Seidman, C. E., Seidman, J. G., & Robbins, J. M. (2005) · Circulation Research · doi:10.1161/01.res.0000190605.79013.4d · Cited by 229 · see citing works

Myosin Binding Protein C, a Phosphorylation-Dependent Force Regulator in Muscle That Controls the Attachment of Myosin Heads by Its Interaction With Myosin S2

Kunst, G., Kress, K. R., Gruen, M., Uttenweiler, D., Gautel, M., & Fink, R. (2000) · Circulation Research · doi:10.1161/01.res.86.1.51 · Cited by 226 · see citing works

Cardiac myosin binding protein c phosphorylation is cardioprotective

Sadayappan, S., Osińska, H. E., Klevitsky, R., Lorenz, J. N., Sargent, M. A., Molkentin, J. D., Seidman, C. E., Seidman, J. G., & Robbins, J. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607069103 · Cited by 211 · see citing works

Top-Down ESI-ECD-FT-ICR Mass Spectrometry Localizes Noncovalent Protein-Ligand Binding Sites

Xie, Y., Zhang, J., Yin, S., & Loo, J. A. (2006) · Journal of the American Chemical Society · doi:10.1021/ja063197p · Cited by 201 · see citing works

cAPK‐phosphorylation controls the interaction of the regulatory domain of cardiac myosin binding protein C with myosin‐S2 in an on‐off fashion

Gruen, M., Prinz, H., & Gautel, M. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00727-9 · Cited by 192 · see citing works

Alteration of myosin cross bridges by phosphorylation of myosin-binding protein C in cardiac muscle.

Weisberg, A. S., & Winegrad, S. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.17.8999 · Cited by 186 · see citing works

Combinatorial Modification of Human Histone H4 Quantitated by Two-dimensional Liquid Chromatography Coupled with Top Down Mass Spectrometry

博一, 長., Bullock, C. R., LeDuc, R. D., Mizzen, C. A., & Kelleher, N. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709796200 · Cited by 185 · see citing works

Differential Roles of Cardiac Myosin-Binding Protein C and Cardiac Troponin I in the Myofibrillar Force Responses to Protein Kinase A Phosphorylation

Stelzer, J. E., Patel, J. R., Walker, J. W., & Moss, R. L. (2007) · Circulation Research · doi:10.1161/circresaha.107.153650 · Cited by 175 · see citing works

Biomolecule Mass Spectrometry

McLafferty, F. W., Fridriksson, E. K., Horn, D. M., Lewis, M. A., & Zubarev, R. A. (1999) · Science · doi:10.1126/science.284.5418.1289 · Cited by 166 · see citing works

Myosin Crossbridge Activation of Cardiac Thin Filaments

Moss, R. L., Razumova, M. V., & Fitzsimons, D. P. (2004) · Circulation Research · doi:10.1161/01.res.0000127125.61647.4f · Cited by 149 · see citing works

Effects of the N-terminal Domains of Myosin Binding Protein-C in an in Vitro Motility Assay

Razumova, M. V., Shaffer, J. F., Tu, A.-Y., Flint, G. V., Regnier, M., & Harris, S. P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m606949200 · Cited by 131 · see citing works

Ablation of Cardiac Myosin-Binding Protein-C Accelerates Stretch Activation in Murine Skinned Myocardium

Stelzer, J. E., Dunning, S. B., & Moss, R. L. (2006) · Circulation Research · doi:10.1161/01.res.0000219863.94390.ce · Cited by 127 · see citing works

Unit resolution mass spectra of 112 kDa molecules with 3 Da accuracy

Kelleher, N. L., Senko, M. W., Siegel, M. M., & McLafferty, F. W. (1997) · Journal of the American Society for Mass Spectrometry · doi:10.1016/s1044-0305(97)00060-3 · Cited by 122 · see citing works

Cardiac myosin-binding protein C decorates F-actin: Implications for cardiac function

Whitten, A. E., Jeffries, C. M., Harris, S. P., & Trewhella, J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808903105 · Cited by 120 · see citing works

Protein Kinase A–Mediated Phosphorylation of cMyBP-C Increases Proximity of Myosin Heads to Actin in Resting Myocardium

Colson, B. A., Bekyarova, T., Locher, M. R., Fitzsimons, D. P., Irving, T. C., & Moss, R. L. (2008) · Circulation Research · doi:10.1161/circresaha.108.178996 · Cited by 120 · see citing works

Unraveling Molecular Complexity of Phosphorylated Human Cardiac Troponin I by Top Down Electron Capture Dissociation/Electron Transfer Dissociation Mass Spectrometry

Zabrouskov, V., Ge, Y., Schwartz, J. C., & Walker, J. W. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700524-mcp200 · Cited by 117 · see citing works

Cardiac Myosin-Binding Protein C (MyBP-C): Identification of Protein Kinase A and Protein Kinase C Phosphorylation Sites

Mohamed, A. S., Dignam, J. D., & Schlender, K. K. (1998) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1998.0857 · Cited by 109 · see citing works

Myosin binding protein C is differentially phosphorylated upon myocardial stunning in canine and rat hearts — Evidence for novel phosphorylation sites

Yuan, C., Guo, Y., Ravi, R., Przyklenk, K., Shilkofski, N. A., Diez, R., Cole, R. N., & Murphy, A. M. (2006) · PROTEOMICS · doi:10.1002/pmic.200500894 · Cited by 88 · see citing works

Detecting Deamidation Products in Proteins by Electron Capture Dissociation

Cournoyer, J. J., Lin, C. T., & O’Connor, P. B. (2005) · Analytical Chemistry · doi:10.1021/ac051691q · Cited by 82 · see citing works

Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry

Ge, Y., ElNaggar, M., Sze, S. K., Oh, H. B., Begley, T. P., McLafferty, F. W., Boshoff, H. I., & Barry, C. E. (2003) · Journal of the American Society for Mass Spectrometry · doi:10.1016/s1044-0305(02)00913-3 · Cited by 79 · see citing works

Stepwise Deamidation of Ribonuclease A at Five Sites Determined by Top Down Mass Spectrometry

Zabrouskov, V., Han, X., Welker, E., Zhai, H., Lin, C., van Wijk, K. J., Scheraga, H. A., & McLafferty, F. W. (2005) · Biochemistry · doi:10.1021/bi0517584 · Cited by 77 · see citing works

A New Approach for Plant Proteomics

Zabrouskov, V., Giacomelli, L., van Wijk, K. J., & McLafferty, F. W. (2003) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m300069-mcp200 · Cited by 73 · see citing works

Increased Coverage in the Transmembrane Domain with Activated-Ion Electron Capture Dissociation for Top-Down Fourier-Transform Mass Spectrometry of Integral Membrane Proteins

Zabrouskov, V., & Whitelegge, J. P. (2007) · Journal of Proteome Research · doi:10.1021/pr0607031 · Cited by 66 · see citing works

Myosin binding protein—C: Enigmatic regulator of cardiac contraction

Oakley, C. E., Chamoun, J. E., Brown, L. J., & Hambly, B. D. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.12.008 · Cited by 65 · see citing works

Characterization of a new qQq-FTICR mass spectrometer for post-translational modification analysis and top-down tandem mass spectrometry of whole proteins

Jebanathirajah, J. A., Pittman, J. L., Thomson, B. A., Budnik, B., Kaur, P., Rapé, M., Kirschner, M. W., Costello, C. E., & O’Connor, P. B. (2005) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2005.08.008 · Cited by 58 · see citing works

Myosin Binding Protein C, a Potential Regulator of Cardiac Contractility

Winegrad, S. (2000) · Circulation Research · doi:10.1161/01.res.86.1.6 · Cited by 52 · see citing works

Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat hearts

Yuan, C., Sheng, Q., Tang, H., Li, Y., Zeng, R., & Solaro, R. J. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00357.2008 · Cited by 45 · see citing works

On studying protein phosphorylation patterns using bottom-up LC–MS/MS: the case of human α-casein

Kjeldsen, F., Savitski, M. M., Nielsen, M. L., Shi, L., & Zubarev, R. A. (2007) · The Analyst · doi:10.1039/b701902e · Cited by 37 · see citing works

Crystal Structure of the C1 domain of Cardiac Myosin Binding Protein-C: Implications for Hypertrophic Cardiomyopathy

Govada, L., Carpenter, L., da Fonseca, P. C. A., Helliwell, J. R., Rizkallah, P. J., Flashman, E., Chayen, N. E., Redwood, C. S., & Squire, J. M. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.02.044 · Cited by 36 · see citing works

Detection of four oxidation sites in viral prolyl‐4‐hydroxylase by top‐down mass spectrometry

Ge, Y., Lawhorn, B. G., ElNaggar, M., Sze, S. K., Begley, T. P., & McLafferty, F. W. (2003) · Protein Science · doi:10.1110/ps.03244403 · Cited by 34 · see citing works

Myosin Binding Protein C in the Heart

de Tombe, P. P. (2006) · Circulation Research · doi:10.1161/01.res.0000225873.63162.c4 · Cited by 33 · see citing works

Mapping intact protein isoforms in discovery mode using top-down proteomics

Tran, J. C., Zamdborg, L., Ahlf, D. R., Lee, J. E., Catherman, A. D., Durbin, K. R., Tipton, J. D., Vellaichamy, A., Kellie, J. F., Li, M., et al. (2011) · Nature · doi:10.1038/nature10575 · Cited by 665 · see citing works

Progress in Top-Down Proteomics and the Analysis of Proteoforms

Toby, T. K., Fornelli, L., & Kelleher, N. L. (2016) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-071015-041550 · Cited by 576 · see citing works

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

Donnelly, D. P., Rawlins, C. M., DeHart, C. J., Fornelli, L., Schachner, L. F., Lin, Z., Lippens, J. L., Aluri, K. C., Sarin, R., Chen, B., et al. (2019) · Nature Methods · doi:10.1038/s41592-019-0457-0 · Cited by 377 · see citing works

Phosphorylation and function of cardiac myosin binding protein-C in health and disease

Barefield, D. Y., & Sadayappan, S. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2009.11.014 · Cited by 273 · see citing works

Mass Spectrometry-Based Detection and Assignment of Protein Posttranslational Modifications

Doll, S., & Burlingame, A. L. (2014) · ACS Chemical Biology · doi:10.1021/cb500904b · Cited by 266 · see citing works

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology

Carrier, L., Mearini, G., Σταθοπούλου, Κ., & Cuello, F. (2015) · Gene · doi:10.1016/j.gene.2015.09.008 · Cited by 225 · see citing works

Principles of electron capture and transfer dissociation mass spectrometry applied to peptide and protein structure analysis

Zhurov, K. O., Fornelli, L., Wodrich, M. D., Laskay, Ü. A., & Tsybin, Y. O. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35477f · Cited by 226 · see citing works

Top‐down proteomics in health and disease: Challenges and opportunities

Gregorich, Z. R., & Ge, Y. (2014) · PROTEOMICS · doi:10.1002/pmic.201300432 · Cited by 217 · see citing works

Top-Down Proteomics: Ready for Prime Time?

Chen, B., Brown, K. A., Lin, Z., & Ge, Y. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.7b04747 · Cited by 210 · see citing works

Top-Down Quantitative Proteomics Identified Phosphorylation of Cardiac Troponin I as a Candidate Biomarker for Chronic Heart Failure

Zhang, J., Guy, M. J., Norman, H. S., Chen, Y.-C., Xu, Q., Dong, X., Guner, H., Wang, S., Kohmoto, T., Young, K. H., et al. (2011) · Journal of Proteome Research · doi:10.1021/pr200258m · Cited by 194 · see citing works

Novel Strategies to Address the Challenges in Top-Down Proteomics

Melby, J. A., Roberts, D. S., Larson, E. J., Brown, K. A., Bayne, E. F., Jin, S., & Ge, Y. (2021) · Journal of the American Society for Mass Spectrometry · doi:10.1021/jasms.1c00099 · Cited by 191 · see citing works

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

Fornelli, L., Damoc, E., Thomas, P. M., Kelleher, N. L., Aizikov, K., Denisov, E. V., Makarov, A., & Tsybin, Y. O. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m112.019620 · Cited by 161 · see citing works

An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins

Xiao, H., Chen, W., Smeekens, J. M., & Wu, R. (2018) · Nature Communications · doi:10.1038/s41467-018-04081-3 · Cited by 154 · see citing works

Top-down proteomics: challenges, innovations, and applications in basic and clinical research

Brown, K. A., Melby, J. A., Roberts, D. S., & Ge, Y. (2020) · Expert Review of Proteomics · doi:10.1080/14789450.2020.1855982 · Cited by 152 · see citing works

Comprehensive Analysis of Protein Modifications by Top-Down Mass Spectrometry

Zhang, H., & Ge, Y. (2011) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.110.957829 · Cited by 148 · see citing works

Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light

Trivedi, D. V., Adhikari, A. S., Sarkar, S. S., Ruppel, K. M., & Spudich, J. A. (2017) · Biophysical Reviews · doi:10.1007/s12551-017-0274-6 · Cited by 147 · see citing works

Top-down proteomics

Roberts, D. S., Loo, J. A., Tsybin, Y. O., Liu, X., Wu, S., Chamot-Rooke, J., Agar, J. N., Paša-Tolić, L., Smith, L. M., & Ge, Y. (2024) · Nature Reviews Methods Primers · doi:10.1038/s43586-024-00318-2 · Cited by 154 · see citing works

Top-down mass spectrometry: Recent developments, applications and perspectives

Cui, W., Rohrs, H. W., & Gross, M. L. (2011) · The Analyst · doi:10.1039/c1an15286f · Cited by 140 · see citing works

Structural Analysis of Intact Monoclonal Antibodies by Electron Transfer Dissociation Mass Spectrometry

Tsybin, Y. O., Fornelli, L., Stoermer, C., Lubeck, M., Parra, J., Nallet, S., Wurm, F. M., & Hartmer, R. (2011) · Analytical Chemistry · doi:10.1021/ac201293m · Cited by 138 · see citing works

MASH Suite Pro: A Comprehensive Software Tool for Top-Down Proteomics

Cai, W., Guner, H., Gregorich, Z. R., Chen, A. J., Ayaz-Guner, S., Peng, Y., Valeja, S. G., Liu, X., & Ge, Y. (2016) · Molecular & Cellular Proteomics · doi:10.1074/mcp.o115.054387 · Cited by 132 · see citing works

Top-Down Structural Analysis of an Intact Monoclonal Antibody by Electron Capture Dissociation-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry

Mao, Y., Valeja, S. G., Rouse, J. C., Hendrickson, C. L., & Marshall, A. G. (2013) · Analytical Chemistry · doi:10.1021/ac303525n · Cited by 129 · see citing works

Native Top-Down Electrospray Ionization-Mass Spectrometry of 158 kDa Protein Complex by High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Li, H., Wolff, J. J., Orden, S. L. V., & Loo, J. A. (2013) · Analytical Chemistry · doi:10.1021/ac4033214 · Cited by 119 · see citing works

Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics

Tucholski, T., Cai, W., Gregorich, Z. R., Bayne, E. F., Mitchell, S. D., McIlwain, S. J., de Lange, W. J., Wrobbel, M., Karp, H., Hite, Z., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2006764117 · Cited by 107 · see citing works

Online Hydrophobic Interaction Chromatography–Mass Spectrometry for Top-Down Proteomics

Chen, B., Peng, Y., Valeja, S. G., Xiu, L., Alpert, A. J., & Ge, Y. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.5b04285 · Cited by 110 · see citing works

Top-down Proteomics Reveals Concerted Reductions in Myofilament and Z-disc Protein Phosphorylation after Acute Myocardial Infarction

Peng, Y., Gregorich, Z. R., Valeja, S. G., Zhang, H., Cai, W., Chen, Y.-C., Guner, H., Chen, A. J., Schwahn, D. J., Hacker, T. A., et al. (2014) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m114.040675 · Cited by 107 · see citing works

Technologies for plasma membrane proteomics

Cordwell, S. J., & Thingholm, T. E. (2009) · PROTEOMICS · doi:10.1002/pmic.200900521 · Cited by 107 · see citing works

Proteomics Research in Cardiovascular Medicine and Biomarker Discovery

Lam, M. P. Y., Ping, P., & Murphy, E. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.10.031 · Cited by 107 · see citing works

Radical solutions: Principles and application of electron-based dissociation in mass spectrometry-based analysis of protein structure

Lermyte, F., Valkenborg, D., Loo, J., & Sobott, F. (2018) · Mass spectrometry reviews (Print) · doi:10.1002/mas.21560 · Cited by 101 · see citing works

Chapter 40 Identification and Quantification of Protein Posttranslational Modifications

Farley, A. R., & Link, A. J. (2009) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(09)63040-8 · Cited by 103 · see citing works

Post-translational Modifications of Integral Membrane Proteins Resolved by Top-down Fourier Transform Mass Spectrometry with Collisionally Activated Dissociation*

Ryan, C., Souda, P., Bassilian, S., Ujwal, R., Zhang, J., Abramson, J., Ping, P., Durazo, A., Bowie, J., Hasan, S., et al. (2010) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m900516-mcp200 · Cited by 91 · see citing works

Top-down Proteomics: Technology Advancements and Applications to Heart Diseases

Cai, W., Tucholski, T. M., Gregorich, Z. R., & Ge, Y. (2016) · Expert Review of Proteomics · doi:10.1080/14789450.2016.1209414 · Cited by 99 · see citing works

Distinct Sarcomeric Substrates Are Responsible for Protein Kinase D-mediated Regulation of Cardiac Myofilament Ca2+ Sensitivity and Cross-bridge Cycling

Bardswell, S. C., Cuello, F., Rowland, A. J., Sadayappan, S., Robbins, J. M., Gautel, M., Walker, J. W., Kentish, J. C., & Avkiran, M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.066456 · Cited by 101 · see citing works

Augmented Phosphorylation of Cardiac Troponin I in Hypertensive Heart Failure

Dong, X., Sumandea, C. A., Chen, Y.-C., Garcia-Cazarin, M. L., Zhang, J., Balke, C. W., Sumandea, M. P., & Ge, Y. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.293258 · Cited by 99 · see citing works

Analysis of Intact Protein Isoforms by Mass Spectrometry

Tipton, J. D., Tran, J. C., Catherman, A. D., Ahlf, D. R., Durbin, K. R., & Kelleher, N. L. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.r111.239442 · Cited by 99 · see citing works

PP2A-B′ holoenzyme substrate recognition, regulation and role in cytokinesis

Wu, C.-G., Chen, H., Guo, F., Yadav, V. K., Mcilwain, S. J., Rowse, M., Choudhary, A., Lin, Z., Li, Y., Gu, T., et al. (2017) · Cell Discovery · doi:10.1038/celldisc.2017.27 · Cited by 85 · see citing works

Automethylation of CARM1 allows coupling of transcription and mRNA splicing

Kuhn, P., Chumanov, R. S., Wang, Y., Ge, Y., Burgess, R. R., & Xu, W. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1246 · Cited by 97 · see citing works

Advancements in Top-Down Proteomics

Zhou, H., Ning, Z., Starr, A. E., Abu‐Farha, M., & Figeys, D. (2011) · Analytical Chemistry · doi:10.1021/ac202882y · Cited by 94 · see citing works

Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains

Valkevich, E. M., Sanchez, N. A., Ge, Y., & Strieter, E. R. (2014) · Biochemistry · doi:10.1021/bi5006305 · Cited by 89 · see citing works

Middle-down approach: a choice to sequence and characterize proteins/proteomes by mass spectrometry

Pandeswari, P. B., & Sabareesh, V. (2019) · RSC Advances · doi:10.1039/c8ra07200k · Cited by 86 · see citing works

Doxorubicin-induced carbonylation and degradation of cardiac myosin binding protein C promote cardiotoxicity

Aryal, B., Jeong, J., & Rao, V. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321783111 · Cited by 83 · see citing works

Myosin Binding Protein C Interaction with Actin

Rybakova, I. N., Greaser, M. L., & Moss, R. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.170605 · Cited by 79 · see citing works

Three Dimensional Liquid Chromatography Coupling Ion Exchange Chromatography/Hydrophobic Interaction Chromatography/Reverse Phase Chromatography for Effective Protein Separation in Top-Down Proteomics

Valeja, S. G., Xiu, L., Gregorich, Z. R., Güner, H., Jin, S., & Ge, Y. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b00657 · Cited by 77 · see citing works

Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics

Fornelli, L., Srzentić, K., Toby, T. K., Doubleday, P. F., Huguet, R., Mullen, C., Melani, R. D., Seckler, H. S., DeHart, C. J., Weisbrod, C. R., et al. (2019) · Molecular & Cellular Proteomics · doi:10.1074/mcp.tir119.001638 · Cited by 75 · see citing works

Revealing Ligand Binding Sites and Quantifying Subunit Variants of Noncovalent Protein Complexes in a Single Native Top-Down FTICR MS Experiment

Li, H., Wongkongkathep, P., Orden, S. L. V., Loo, R. R. O., & Loo, J. A. (2014) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-014-0928-6 · Cited by 75 · see citing works

MASH Suite: A User-Friendly and Versatile Software Interface for High-Resolution Mass Spectrometry Data Interpretation and Visualization

Guner, H., Close, P. L., Cai, W., Zhang, H., Peng, Y., Gregorich, Z. R., & Ge, Y. (2014) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-013-0789-4 · Cited by 73 · see citing works

Effective Enrichment and Mass Spectrometry Analysis of Phosphopeptides Using Mesoporous Metal Oxide Nanomaterials

Nelson, C. A., Szczech, J. R., Dooley, C. J., Xu, Q., Lawrence, M. J., Zhu, H., Jin, S., & Ge, Y. (2010) · Analytical Chemistry · doi:10.1021/ac100877a · Cited by 74 · see citing works

Thick Filament Protein Network, Functions, and Disease Association

Wang, L., Geist, J., Grogan, A., Hu, L. R., & Kontrogianni‐Konstantopoulos, A. (2018) · Comprehensive physiology · doi:10.1002/cphy.c170023 · Cited by 80 · see citing works

Proteomics in heart failure: top-down or bottom-up?

Gregorich, Z. R., Chang, Y.-H., & Ge, Y. (2014) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-014-1471-9 · Cited by 69 · see citing works

Specific Enrichment of Phosphoproteins Using Functionalized Multivalent Nanoparticles

Hwang, L., Ayaz-Guner, S., Gregorich, Z. R., Cai, W., Valeja, S. G., Jin, S., & Ge, Y. (2015) · Journal of the American Chemical Society · doi:10.1021/ja511833y · Cited by 70 · see citing works

Identification of Novel Protein Kinase A Phosphorylation Sites in the M-domain of Human and Murine Cardiac Myosin Binding Protein-C Using Mass Spectrometry Analysis

Jia, W., Shaffer, J. F., Harris, S. P., & Leary, J. A. (2010) · Journal of Proteome Research · doi:10.1021/pr901006h · Cited by 70 · see citing works

Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer

Fornelli, L., Ayoub, D., Aizikov, K., Liu, X., Damoc, E., Pevzner, P. A., Makarov, A., Beck, A., & Tsybin, Y. O. (2017) · Journal of Proteomics · doi:10.1016/j.jprot.2017.02.013 · Cited by 70 · see citing works

Sequencing Larger Intact Proteins (30–70 kDa) with Activated Ion Electron Transfer Dissociation

Riley, N., Westphall, M., & Coon, J. (2017) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-017-1808-7 · Cited by 55 · see citing works

Top‐down mass spectrometry for the analysis of combinatorial post‐translational modifications

Lanucara, F., & Eyers, C. E. (2012) · Mass Spectrometry Reviews · doi:10.1002/mas.21348 · Cited by 67 · see citing works

Unit Mass Baseline Resolution for an Intact 148 kDa Therapeutic Monoclonal Antibody by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Valeja, S. G., Kaiser, N. K., Xian, F., Hendrickson, C. L., Rouse, J. C., & Marshall, A. G. (2011) · Analytical Chemistry · doi:10.1021/ac202429c · Cited by 67 · see citing works

Deciphering modifications in swine cardiac troponin I by top-down high-resolution tandem mass spectrometry

Zhang, J., Dong, X., Hacker, T. A., & Ge, Y. (2010) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2010.02.005 · Cited by 66 · see citing works

Protein kinase A–induced myofilament desensitization to Ca2+ as a result of phosphorylation of cardiac myosin–binding protein C

Chen, P. P., Patel, J. R., Rybakova, I. N., Walker, J. W., & Moss, R. L. (2010) · The Journal of General Physiology · doi:10.1085/jgp.201010448 · Cited by 64 · see citing works

Multiplexed Middle-Down Mass Spectrometry as a Method for Revealing Light and Heavy Chain Connectivity in a Monoclonal Antibody

Srzentić, K., Nagornov, K. O., Fornelli, L., Lobas, A. A., Ayoub, D., Kozhinov, A. N., Gasilova, N., Menin, L., Beck, A., Gorshkov, M. V., et al. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.8b02398 · Cited by 55 · see citing works

Earning stripes: myosin binding protein-C interactions with actin

van Dijk, S. J., Kooiker, K. B., & Harris, S. P. (2014) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1432-8 · Cited by 56 · see citing works

Phosphoproteomics with Activated Ion Electron Transfer Dissociation

Riley, N. M., Hebert, A. S., Dürnberger, G., Stanek, F., Mechtler, K., Westphall, M. S., & Coon, J. J. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00212 · Cited by 55 · see citing works

Purification and High-Resolution Top-Down Mass Spectrometric Characterization of Human Salivary α-Amylase

Peng, Y., Chen, X., Sato, T., Rankin, S. A., Tsuji, R. F., & Ge, Y. (2012) · Analytical Chemistry · doi:10.1021/ac300083y · Cited by 51 · see citing works

Top-Down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light-Chain Phosphorylation That Contributes to Sarcopenic Muscle Dysfunction

Gregorich, Z. R., Peng, Y., Cai, W., Jin, Y., Wei, L., Chen, A. J., McKiernan, S. H., Aiken, J. M., Moss, R. L., Diffee, G. M., et al. (2016) · Journal of Proteome Research · doi:10.1021/acs.jproteome.6b00244 · Cited by 51 · see citing works

A Top-Down Proteomics Platform Coupling Serial Size Exclusion Chromatography and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Tucholski, T., Knott, S. J., Chen, B., Pistono, P., Lin, Z., & Ge, Y. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.8b04082 · Cited by 49 · see citing works

Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications (PTMs) in Skeletal Muscles Identified by Top-down Proteomics

Wei, L., Gregorich, Z. R., Lin, Z., Cai, W., Jin, Y., McKiernan, S. H., McIlwain, S., Aiken, J. M., Moss, R. L., Diffee, G. M., et al. (2018) · Molecular & Cellular Proteomics · doi:10.1074/mcp.ra117.000124 · Cited by 47 · see citing works

Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way

Fert-Bober, J., Murray, C. I., Parker, S. J., & Van Eyk, J. E. (2018) · Circulation Research · doi:10.1161/circresaha.118.310966 · Cited by 45 · see citing works

Myocardial Infarction-induced N-terminal Fragment of Cardiac Myosin-binding Protein C (cMyBP-C) Impairs Myofilament Function in Human Myocardium

Witayavanitkul, N., Mou, Y. A., Kuster, D. W. D., Khairallah, R. J., Sarkey, J. P., Govindan, S., Chen, X., Ge, Y., Rajan, S., Wieczorek, D. F., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.541128 · Cited by 47 · see citing works

New Protein Footprinting: Fast Photochemical Iodination Combined with Top-Down and Bottom-Up Mass Spectrometry

Chen, J., Cui, W., Giblin, D. E., & Gross, M. L. (2012) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-012-0403-1 · Cited by 47 · see citing works

Increased Protein Structural Resolution from Diethylpyrocarbonate-based Covalent Labeling and Mass Spectrometric Detection

Zhou, Y., & Vachet, R. W. (2012) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-011-0332-4 · Cited by 45 · see citing works

Top-down Targeted Proteomics for Deep Sequencing of Tropomyosin Isoforms

Peng, Y., Chen, X., Zhang, H., Xu, Q., Hacker, T. A., & Ge, Y. (2012) · Journal of Proteome Research · doi:10.1021/pr301054n · Cited by 44 · see citing works

Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer.

Kline, J. T., Mullen, C. H., Durbin, K. R., Oates, R. N., Huguet, R., Syka, J. E., & Fornelli, L. (2021) · Journal of the American Society for Mass Spectrometry · doi:10.1021/jasms.1c00062 · Cited by 39 · see citing works

In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry

Peng, Y., Yu, D., Gregorich, Z., Chen, X., Beyer, A. M., Gutterman, D. D., & Ge, Y. (2013) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-013-9352-y · Cited by 42 · see citing works

Proteomics of the heart

Karpov, O. A., Stotland, A. B., Raedschelders, K., Chazarin, B., Ai, L., Murray, C. I., & Eyk, J. E. V. (2024) · Physiological Reviews · doi:10.1152/physrev.00026.2023 · Cited by 42 · see citing works

In Vivo Cardiac Myosin Binding Protein C Gene Transfer Rescues Myofilament Contractile Dysfunction in Cardiac Myosin Binding Protein C Null Mice

Merkulov, S. M., Chen, X., Chandler, M. P., & Stelzer, J. E. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.112.968941 · Cited by 42 · see citing works

Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry

Gregorich, Z. R., Cai, W., Lin, Z., Chen, A. J., Peng, Y., Kohmoto, T., & Ge, Y. (2017) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2017.04.002 · Cited by 42 · see citing works

Nano-LC FTICR Tandem Mass Spectrometry for Top-Down Proteomics: Routine Baseline Unit Mass Resolution of Whole Cell Lysate Proteins up to 72 kDa

Tipton, J. D., Tran, J. C., Catherman, A. D., Ahlf, D. R., Durbin, K. R., Lee, J. E., Kellie, J. F., Kelleher, N. L., Hendrickson, C. L., & Marshall, A. G. (2012) · Analytical Chemistry · doi:10.1021/ac202651v · Cited by 40 · see citing works

Dissociation techniques in mass spectrometry-based proteomics

Jones, A. W., & Cooper, H. J. (2011) · The Analyst · doi:10.1039/c0an01011a · Cited by 40 · see citing works

Top-down Proteomics of Endogenous Membrane Proteins Enabled by Cloud Point Enrichment and Multidimensional Liquid Chromatography-Mass Spectrometry

Brown, K. A., Tucholski, T., Alpert, A. J., Eken, C., Wesemann, L., Kyrvasilis, A., Jin, S., & Ge, Y. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c02533 · Cited by 35 · see citing works

Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation

Chen, B., Lin, Z., Zhu, Y., Jin, Y., Larson, E., Xu, Q., Fu, C., Zhang, Z., Zhang, Q., Pritts, W. A., et al. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b02194 · Cited by 38 · see citing works

Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro

Govindan, S., Sarkey, J. P., Ji, X., Sundaresan, N. R., Gupta, M. P., de Tombe, P. P., & Sadayappan, S. (2012) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-012-9292-y · Cited by 37 · see citing works

A multi-scale strategy for discovery of novel endogenous neuropeptides in the crustacean nervous system

Jia, C., Lietz, C. B., Ye, H., Hui, L., Yu, Q., Yoo, S., & Li, L. (2013) · Journal of Proteomics · doi:10.1016/j.jprot.2013.06.021 · Cited by 36 · see citing works

Comprehensive analysis of tropomyosin isoforms in skeletal muscles by top-down proteomics

Jin, Y., Peng, Y., Lin, Z., Chen, Y., Wei, L., Hacker, T. A., Larsson, L., & Ge, Y. (2016) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-016-9443-7 · Cited by 36 · see citing works

Structural Analysis of Biomolecules through a Combination of Mobility Capillary Electrophoresis and Mass Spectrometry

He, M., Luo, P., Hong, J., Wang, X., Wu, H., Zhang, R., Qu, F., Xiang, Y., & Xu, W. L. (2019) · ACS Omega · doi:10.1021/acsomega.8b03224 · Cited by 38 · see citing works

High-definition De Novo Sequencing of Crustacean Hyperglycemic Hormone (CHH)-family Neuropeptides

Jia, C., Hui, L., Cao, W., Lietz, C. B., Jiang, X., Chen, R., Catherman, A. D., Thomas, P. M., Ge, Y., Kelleher, N. L., et al. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m112.020537 · Cited by 35 · see citing works

Complete Characterization of Cardiac Myosin Heavy Chain (223 kDa) Enabled by Size-Exclusion Chromatography and Middle-Down Mass Spectrometry

Jin, Y., Wei, L., Cai, W., Lin, Z., Wu, Z., Peng, Y., Kohmoto, T., Moss, R. L., & Ge, Y. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00113 · Cited by 35 · see citing works

Phosphorylation, but Not Alternative Splicing or Proteolytic Degradation, Is Conserved in Human and Mouse Cardiac Troponin T

Zhang, J., Zhang, H., Ayaz‐Güner, Ş., Chen, Y., Dong, X., Xu, Q., & Ge, Y. (2011) · Biochemistry · doi:10.1021/bi2006256 · Cited by 34 · see citing works

Ultrahigh pressure fast size exclusion chromatography for top‐down proteomics

Chen, X., & Ge, Y. (2013) · PROTEOMICS · doi:10.1002/pmic.201200594 · Cited by 33 · see citing works

Effective Top-Down LC/MS+ Method for Assessing Actin Isoforms as a Potential Cardiac Disease Marker

Chen, Y.-C., Ayaz-Guner, S., Peng, Y., Lane, N. M., Locher, M. R., Kohmoto, T., Larsson, L., Moss, R. L., & Ge, Y. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b01745 · Cited by 31 · see citing works

Analytical Aspects of Proteomics: 2009–2010

Ning, Z., Zhou, H., Wang, F., Abu‐Farha, M., & Figeys, D. (2011) · Analytical Chemistry · doi:10.1021/ac200857t · Cited by 31 · see citing works

Modern approaches for investigating epigenetic signaling pathways

Evertts, A. G., Zee, B. M., & Garcia, B. A. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00007.2010 · Cited by 30 · see citing works

Top‐down mass spectrometry of cardiac myofilament proteins in health and disease

Peng, Y., Ayaz‐Güner, Ş., Yu, D., & Ge, Y. (2014) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.201400043 · Cited by 29 · see citing works

Limited Proteolysis via Millisecond Digestions in Protease-Modified Membranes

Tan, Y.-J., Wang, W., Zheng, Y., Dong, J., Stefano, G., Brandizzí, F., Garavito, R. M., Reid, G. E., & Bruening, M. L. (2012) · Analytical Chemistry · doi:10.1021/ac3019153 · Cited by 29 · see citing works

Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry for Characterizing Proteoforms

Tucholski, T., & Ge, Y. (2020) · Mass spectrometry reviews (Print) · doi:10.1002/mas.21653 · Cited by 18 · see citing works

Extending the Isotopically Resolved Mass Range of Orbitrap Mass Spectrometers

Shaw, J. B., & Brodbelt, J. S. (2013) · Analytical Chemistry · doi:10.1021/ac401634b · Cited by 28 · see citing works

A preferred AMPK phosphorylation site adjacent to the inhibitory loop of cardiac and skeletal troponin I

Solis, R. S., Ge, Y., & Walker, J. W. (2011) · Protein Science · doi:10.1002/pro.623 · Cited by 26 · see citing works

Top-down mass spectrometry of histone modifications in sorghum reveals potential epigenetic markers for drought acclimation

Zhou, M., Malhan, N., Ahkami, A. H., Engbrecht, K., Myers, G., Dahlberg, J., Hollingsworth, J., Sievert, J. A., Hutmacher, R., Madera, M., et al. (2020) · Methods · doi:10.1016/j.ymeth.2019.10.007 · Cited by 23 · see citing works

Pilot Evaluation of the Long-Term Reproducibility of Capillary Zone Electrophoresis–Tandem Mass Spectrometry for Top-Down Proteomics of a Complex Proteome Sample

Sadeghi, S. A., Chen, W., Wang, Q., Wang, Q., Fang, F., Liu, X., & Sun, L. (2024) · Journal of Proteome Research · doi:10.1021/acs.jproteome.3c00872 · Cited by 25 · see citing works

Post-translational regulation of cardiac myosin binding protein-C: A graphical review

Main, A., Fuller, W., & Baillie, G. S. (2020) · Cellular Signalling · doi:10.1016/j.cellsig.2020.109788 · Cited by 25 · see citing works

Automatic Figure Ranking and User Interfacing for Intelligent Figure Search

Yu, H. Q., Liu, F., & Ramesh, B. P. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012983 · Cited by 25 · see citing works

Top-down high-resolution electron capture dissociation mass spectrometry for comprehensive characterization of post-translational modifications in Rhesus monkey cardiac troponin I

Xu, F., Xu, Q., Dong, X., Guy, M. J., Güner, H., Hacker, T. A., & Ge, Y. (2010) · International Journal of Mass Spectrometry · doi:10.1016/j.ijms.2010.09.007 · Cited by 23 · see citing works

The impact of antibody selection on the detection of cardiac troponin I

Guy, M. J., Chen, Y., Clinton, L., Zhang, H., Zhang, J., Dong, X., Xu, Q., Ayaz‐Güner, Ş., & Ge, Y. (2012) · Clinica Chimica Acta · doi:10.1016/j.cca.2012.10.034 · Cited by 23 · see citing works

The Peptidome Comes of Age: Mass Spectrometry-Based Characterization of the Circulating Cancer Peptidome

Greening, D. W., Kapp, E. A., & Simpson, R. J. (2017) · The Enzymes · doi:10.1016/bs.enz.2017.08.003 · Cited by 23 · see citing works

Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts

Kooij, V., Holewinski, R. J., Murphy, A. M., & Eyk, J. E. V. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.04.012 · Cited by 74 · see citing works

Identification of Novel Protein Kinase A Phosphorylation Sites in the M-domain of Human and Murine Cardiac Myosin Binding Protein-C Using Mass Spectrometry Analysis

Jia, W., Shaffer, J. F., Harris, S. P., & Leary, J. A. (2010) · Journal of Proteome Research · doi:10.1021/pr901006h · Cited by 70 · see citing works

Cardiac Myosin-Binding Protein-C Phosphorylation and Cardiac Function

Sadayappan, S., Gulick, J. M., Osińska, H. E., Martin, L. A., Hahn, H. S., Dorn, G. W., Klevitsky, R., Seidman, C. E., Seidman, J. G., & Robbins, J. M. (2005) · Circulation Research · doi:10.1161/01.res.0000190605.79013.4d · Cited by 229 · see citing works

P679Ultrastructural and electron tomography analyses of cardiac muscle: normal muscle compared to presence and absence of myosin binding protein C-phosphorylation

Torre, I., Jeddi, M., Amat‐Roldan, I., Hunter, S., Sadayappan, S., Robbins, J. M., Moss, R. L., & Luther, P. K. (2014) · Cardiovascular Research · doi:10.1093/cvr/cvu098.103

COOH-terminal truncated human cardiac MyBP-C alters myosin filament organization

Sébillon, P., Bonne, G., Flavigny, J., Venin, S., Rouche, A., Fiszman, M. Y., Vikstrom, K. L., Leinwand, L. A., Carrier, L., & Schwartz, K. (2001) · Comptes Rendus de l Académie des Sciences - Series III - Sciences de la Vie · doi:10.1016/s0764-4469(00)01292-0 · Cited by 17 · see citing works