The DOI matches its Crossref record; 119 of the 119 references it cites were found in a registry or an index; none of the 99 sources its claims cite is checked for support yet.
Autism as a disorder of prediction
Open accessAbstract
Significance: Autism is characterized by diverse behavioral traits. Guided by theoretical considerations and empirical data, this paper develops the hypothesis that many of autism's salient traits may be manifestations of an underlying impairment in predictive abilities. This impairment renders an otherwise orderly world to be experienced as a capriciously “magical” one. The hypothesis elucidates the information-processing roots of autism and, thereby, can aid the identification of neural structures likely to be differentially affected. Behavioral and neural measures of prediction might serve as early assays of predictive abilities in infants, and serve as useful tools in intervention design and in monitoring their effectiveness. The hypothesis also points to avenues for further research to determine molecular and circuit-level causal underpinnings of predictive impairments.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
0 of 99 cited sources checked · 0 supported · 0 flagged
None of the sources cited for this claim have been checked yet.
In the paper
“The underlying domains all constitute temporally unfolding Markov systems, with progressions from one state to another governed by probabilistic links (Fig. 1 A ).”
What the sources say
- Not checked yetcites [3] source
- Not checked yetcites [4] source
- Not checked yetcites [5] source
- Not checked yetcites [6] source
- Not checked yetcites [7] source
- Not checked yetcites [8] source
- Not checked yetcites [9]
- Not checked yetcites [10] source
- Not checked yetcites [11] source
- Not checked yetcites [12] source
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesA conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“As a consequence of this shift, several relationships that are evident to a neurotypical individual would become undetectable to a person with autism.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIn the paper
“It is estimated that more than one-third of all individuals on the autism spectrum display some form of IoS (14).”
What the sources say
- Not checked yetcites [14] source
Strength:hedged· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIn the paper
“Insistence on sameness (IoS) is a hallmark feature of autism.”
What the sources say
- Not checked yetcites [15] source
Strength:boosted· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesNone of the sources cited for this claim have been checked yet.
In the paper
“Predictability is a fundamental modulator of anxiety in that reduction in the ability to predict events, even without any associated aversive consequence, enhances anxious responses (21, 22).”
What the sources say
- Not checked yetcites [21] Abbott BB, Badia P (1986) Predictable versus unpredictable shock conditions and physiological measures of stress: A reply to Arthur. Psychol Bull 100:384 -387. source
- Not checked yetcites [22] Herry C, et al. (2007) Processing of temporal unpredictability in human and animal amygdala. J Neurosci 27(22):5958 -5966. source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesNone of the sources cited for this claim have been checked yet.
In the paper
“Past research with diverse populations has shown that environmental unpredictability is strongly correlated with anxiety (16 -20).”
What the sources say
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesNone of the sources cited for this claim have been checked yet.
In the paper
“These hypersensitivities cannot be explained as outcomes of abnormally enhanced sensation (29 -31).”
What the sources say
- Not checked yetcites [29] DePape A-MR, Hall GBC, Tillmann B, Trainor LJ (2012) Auditory processing in highfunctioning adolescents with autism spectrum disorder. PLoS ONE 7(9):e44084. source
- Not checked yetcites [30] Bölte S, et al. (2012) A close eye on the eagle-eyed visual acuity hypothesis of autism. J Autism Dev Disord 42(5):726 -733. source
- Not checked yetcites [31] Ashwin E, Ashwin C, Rhydderch D, Howells J, Baron-Cohen S (2009) Eagle-eyed visual acuity: An experimental investigation of enhanced perception in autism. Biol Psychiatry 65(1):17 -21. source
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesA conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“suggesting that stimming may be an anxiolytic response to a chaotic world: an attempt to drown out the influx of unpredictable environmental information by self-generated periodic and, hence, more predictable information.”
Strength:hedged· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesA conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“A direct corollary is that reduced habituation reduces stimulus suppression.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes- Rests on an assumption: Habituation suppresses sustained stimulation.
None of the sources cited for this claim have been checked yet.
In the paper
“Studies with neurologically healthy humans and animals reveal that the ritualistic behaviors that emerge under conditions of unpredictability serve as a calming response to an externally imposed stressor (25, 26).”
What the sources say
- Not checked yetcites [25] Maier NRF (1939) Studies of Abnormal Behavior in the Rat (Harper, New York).
- Not checked yetcites [26] Eilam D, Izhar R, Mort J (2011) Threat detection: Behavioral practices in animals and humans. Neurosci Biobehav Rev 35(4):999 -1006. source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Probably not a substantial claim. 14
- It may state two separate claims as one. 14
- The quote only partly states this claim. 1
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“we describe how theoretical considerations and a review of empirical data lead to the hypothesis that some salient aspects of the autism phenotype may be manifestations of an underlying impairment in predictive abilities.”
Tests✗ Asserted: fails✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. The authors may not put it forward as true.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The hypothesis of predictive impairment in autism (PIA) posits that autism may be associated with inaccuracies in estimating the P (B j A, Δ t ) conditional probability.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✗ Based: failsProbably not a substantial claim. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“To perform well in these domains, one necessarily needs to estimate the underlying Markov system, i.e., the matrix of interstate transition probabilities.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✗ Based: failsProbably not a substantial claim. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“A reduction in one ' s predictive ability would, in this space, manifest as a shift of the ASF toward the upper left.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“from an observed temporal sequence, the brain has to estimate the conditional probability P (B j A, Δ t )”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim.
In the paper
“It is estimated that nearly 90% of all children on the autism spectrum suffer from sensory abnormalities, often hypersensitivities, to stimuli that a neurotypical individual could easily ignore (28).”
What the sources say
- Not checked yetcites [28] Leekam SR, Nieto C, Libby SJ, Wing L, Gould J (2007) Describing the sensory abnormalities of children and adults with autism. J Autism Dev Disord 37(5):894 -910. source
Strength:hedged· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Taken together, these results suggest that rituals and an insistence on sameness may be a consequence of, and a way to mitigate, anxiety arising out of unpredictability.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“a parsimonious interpretation of the reliance on rituals and stimming behaviors observed in autism is that they emerge from, and represent attempts to minimize, the consequences of unpredictability.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes? Based: unclearIt may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“A key determinant of habituation is stimulus predictability. For typically developing subjects, predictability of a sequence is directly proportional to the extent of habituation it induces (22, 34 -36).”
What the sources say
- Not checked yetcites [22] Herry C, et al. (2007) Processing of temporal unpredictability in human and animal amygdala. J Neurosci 27(22):5958 -5966. source
- Not checked yetcites [34] Sokolov EN (1960) The Central Nervous System and Behavior III (Macy Foundation, New York).
- Not checked yetcites [35] McDaniel JW (1964) The effects of stimulus predictability upon auditory habituation and acquisition. Dissertation (Texas Technical College, Lubbock, TX).
- Not checked yetcites [36] Turk-Browne NB, Scholl BJ, Chun MM (2008) Babies and brains: Habituation in infant cognition and functional neuroimaging. Front Hum Neurosci 2:16.
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
In the paper
“Computational systems for dynamic object tracking rely on predictive techniques such as Kalman filtering (46). These systems demonstrate that a key consequence of impaired prediction is errors in online position estimation.”
What the sources say
- Not checked yetcites [46] Welch G, Bishop G (2001) An introduction to the Kalman Filter. Proc SIGGRAPH 2001 (Association for Computing Machinery, Los Angeles), pp 19 -24.
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Reduction in discerning predictive relationships between events in a stimulus sequence would reduce a person ' s ability to predict the onset of the next event. Such a lack of predictability would compromise habituation and lead to hypersensitivity.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
- Rests on an assumption: Habituation suppresses sustained stimulation.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Theory of mind requires the ability to ascribe invisible causes to observations about a person by connecting past history with current behavior.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“the PIA hypothesis suggests that an endogenous predictive impairment causes environmental stimuli to appear more chaotic, leading to reduced habituation and hence greater stress.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
- Rests on an assumption: Habituation suppresses sustained stimulation.
None of the sources cited for this claim have been checked yet.
In the paper
“Several studies have demonstrated that unpredictability of stressors is one of the key aspects of torture and leads to the development of anxiety, fear, and aversion (19, 37).”
What the sources say
- Not checked yetcites [19] source
- Not checked yetcites [37] Bas ¸o glu M, Mineka S (1992) The role of uncontrollable and unpredictable stress in posttraumatic stress responses in torture survivors. Torture and Its Consequences: Current Treatment Approaches (Cambridge Univ Press, Cambridge, UK), pp 185 -255.
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“If the prediction systems of the brain are differentially affected in autism, then one can expect that the skills left largely untouched would be the ones that are deterministic and where good performance does not depend on estimates of temporally unfolding conditional probabilities.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Hyperarousal of these structures would, in turn, be expected to lead to hypermalleability of learning; current exposure would have disproportionate weight and supersede earlier experience, constituting a kind of ' hyperplasticity. '”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Most of them, especially mathematics calendar calculations and music, are strongly rule-based, and, thus, minimize uncertainty of outcomes. Furthermore, with the exception of music, they are static, thereby obviating the need for prediction over time.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“More recent studies (84, 85) have also documented these observations.”
What the sources say
- Not checked yetcites [84] Lyons V, Fitzgerald M (2004) Humor in autism and Asperger syndrome. J Autism Dev Disord 34(5):521 -531. source
- Not checked yetcites [85] Samson AC, Huber O, Ruch W (2013) Seven decades after Hans Asperger ' s observations: A comprehensive study of humor in individuals with Autism Spectrum Disorders. Humor 26:441 -460. source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“In describing his patients, Hans Asperger had noted that ' an essential characteristic of these children is their humorlessness. They do not understand jokes . . . ' (83).”
What the sources say
- Not checked yetcites [83] Asperger H (1944) Die ' Autistischen Psychopathen ' im Kindesalter. Eur Arch Psychiatry Clin Neurosci 117:76 -136.
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, the notion of core impairments, shared by most cases of autism, seems to be at odds with the heterogeneity of the phenotype.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Based on theoretical considerations and a review of past literature, we believe that predictive impairment may constitute an endophenotype shared across individuals.”
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesThe quote only partly states this claim.
None of the sources cited for this claim have been checked yet.
In the paper
“Autism can have many etiologies, and yet, there is some commonality across manifestations, hence a shared clinical diagnosis.”
What the sources say
- Not checked yetcites [98] Tager-Flusberg H, Joseph RM (2003) Identifying neurocognitive phenotypes in autism. Philos Trans R Soc Lond B Biol Sci 358(1430):303 -314. source
- Not checked yetcites [99] Losh M, Childress D, Lam K, Piven J (2008) Defining key features of the broad autism phenotype: A comparison across parents of multiple- and single-incidence autism families. Am J Med Genet B Neuropsychiatr Genet 147B(4):424 -433. source
- Not checked yetcites [100] Jones W, Klin A (2009) Heterogeneity and homogeneity across the autism spectrum: The role of development. J Am Acad Child Adolesc Psychiatry 48(5):471 -473. source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Such parametric differences may help account for the phenotypic variability observed across individuals on the autism spectrum and also potentially provide the basis for a principled taxonomy of different autism subtypes.”
Tests✓ Asserted: passes? Checkable: unclear✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Although it is certainly possible that the different autistic traits have different etiologies, what is appealing about the PIA hypothesis is its parsimony -an account that is able to provide a unifying explanation for not just a single trait, but for several of them.”
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✗ Checkable: fails✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may be too vague to check against evidence.
In the paper
“Motor difficulties are believed to arise from abnormalities in the cerebellum (106).”
What the sources say
- Not checked yetcites [106] Mostofsky SH, et al. (2009) Decreased connectivity and cerebellar activity in autism during motor task performance. Brain 132(Pt 9):2413 -2425. source
Strength:hedged· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“Explanatory accounts have indeed been offered for each of the autistic traits we have described in Sections 2 and 3 .”
What the sources say
- Not checked yetcites [102] Takeuchi M, Harada M, Nishitani H (2002) Deficiency of ' theory of mind ' in autism estimated by fMRI. Int Congr Ser 1232:737 -740. source
- Not checked yetcites [103] Gallese V, Goldman A (1998) Mirror neurons and the simulation theory of mindreading. Trends Cogn Sci 2(12):493 -501. source
- Not checked yetcites [104] Hadjikhani N (2007) Mirror neuron system and autism Progress in Autism Research , ed Carlisle PC, (Nova Science Publishers, Happauge, NY), pp 151 -166.
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim.
None of the sources cited for this claim have been checked yet.
In the paper
“For instance, difficulties in Theory of Mind have been suggested as arising from abnormalities of the cortical substrates for social cognition (102) or in the mirror neuron system (refs. 103 and 104 but see 105).”
What the sources say
- Not checked yetcites [102] Takeuchi M, Harada M, Nishitani H (2002) Deficiency of ' theory of mind ' in autism estimated by fMRI. Int Congr Ser 1232:737 -740. source
- Not checked yetcites [103] Gallese V, Goldman A (1998) Mirror neurons and the simulation theory of mindreading. Trends Cogn Sci 2(12):493 -501. source
- Not checked yetcites [104] Hadjikhani N (2007) Mirror neuron system and autism Progress in Autism Research , ed Carlisle PC, (Nova Science Publishers, Happauge, NY), pp 151 -166.
Strength:hedged· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
The paper relies on this without support.
Autism has multiple causes.
“Autism likely owes its genesis to a multiplicity of causes.”
The paper relies on this without support.
Habituation suppresses sustained stimulation.
“A key role in suppressing sustained stimulation is played by our ability to habituate.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“There may be important differences in neurobiological, emotional and cognitive responses to stressors for autistic people, which warrant tailored anxiety models, assessments and interventions [24].”
From Autistic Cognition: Charting Routes to Anxiety (2021) · cites this paper as [24]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“with autism even being cast as a 'disorder of prediction' [136].”
From How Do Expectations Shape Perception? (2018) · cites this paper as [136]
In the citing paper
“In the elaboration of the Bayesian brain hypothesis of ASD (2) and subsequent theoretical papers (3, 4, 97–99), results from numerous earlier cognitive and psychophysical studies were re-interpreted post hoc in the novel framework.”
From Can Bayesian Theories of Autism Spectrum Disorder Help Improve Clinical Practice? (2016) · cites this paper as [99]
In the citing paper
“A theory of ASD that is rapidly gaining credibility is the notion that individuals with ASD do not have a robust historical representation of the world. This lack of a probabilistic “map” of the world makes it difficult for those with ASD to predict upcoming events, and this lack of predictive coding thus limits interactions with the external environment (Pellicano and Burr, 2012; Sinha et al., 2”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Sinha et al., 2014
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Reinforcement Learning: An Introduction
Sutton, R. S., & Barto, A. G. (1998) · IEEE Transactions on Neural Networks · doi:10.1109/tnn.1998.712192 · Cited by 27,225
Reinforcement Learning: An Introduction
Sutton, R. S., & Barto, A. (2005) · IEEE Transactions on Neural Networks · doi:10.1109/tnn.2004.842673 · Cited by 25,268
A neural substrate of prediction and reward
Schultz, W., Dayan, P., & Montague, P. R. (1997) · Science · doi:10.1126/science.275.5306.1593 · Cited by 9,388
Lord, C., Rutter, M., & Le Couteur, A. (1994) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172145 · Cited by 9,065
(1943) · The Nervous child · Cited by 8,870
Does the autistic child have a “theory of mind” ?
Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985) · Cognition · doi:10.1016/0010-0277(85)90022-8 · Cited by 8,599
Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005592401947 · Cited by 7,520
Whatever next? Predictive brains, situated agents, and the future of cognitive science
Clark, A. (2013) · Behavioral and Brain Sciences · doi:10.1017/s0140525x12000477 · Cited by 5,924 · cited 1×
“This program of research can build on the exciting body of recent work that has been investigating the prediction and reward machinery in the neurotypical brain, both in humans and other animals (108).”
Background
Flagged first, then by citations
Research works printed but not linked: 1
- G Welch G Bishop An introduction to the Kalman Filter. Proc SIGGRAPH 2001 (Association for Computing Machinery Los Angeles) pp 19–24. (2001).
Cited by
Sorted by citations
Items 101–200 of 560
Topál, J., Román, V., & Turcsán, B. (2019) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1495 · Cited by 46
Kinard, J. L., Mosner, M. G., Greene, R. K., Addicott, M. A., Bizzell, J., Petty, C., Cernasov, P., Walsh, E. C., Eisenlohr-Moul, T. A., Carter, R. M., et al. (2020) · Autism Research · doi:10.1002/aur.2273 · Cited by 51
“Moreover, these results are consistent with more recent theories that ASD is a disorder characterized by impaired predictive abilities [Sinha et al., 2014].”
BackgroundMethodResultInfluentialKelly, E., Escamilla, C. O., & Tsai, P. T. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.11.012 · Cited by 46
Ursino, M., Serra, M., Tarasi, L., Ricci, G., Magosso, E., & Romei, V. (2022) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2022.932128 · Cited by 48
“This imbalance, in turn, may result in poor social adaptation and insufficient appropriateness to social requirements (Sinha et al., 2014).”
BackgroundVenker, C. E., Edwards, J., Saffran, J. R., & Ellis Weismer, S. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-018-3778-4 · Cited by 42
Coll, M., Whelan, E., Catmur, C., & Bird, G. (2020) · Cognition · doi:10.1016/j.cognition.2020.104236 · Cited by 42
“This predictive coding account of perception has recently been suggested to explain some of the symptoms associated with Autism Spectrum Disorder (henceforth ‘autism’), based on the hypothesis that autism is associated with an alteration of the relative precision of bottom-up and top-down signals (Brock, 2012; Lawson,…”
BackgroundPierce, S., Kadlaskar, G., Edmondson, D. A., McNally Keehn, R., Dydak, U., & Keehn, B. (2021) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-020-09351-0 · Cited by 42
Bowsher-Murray, C., Gerson, S. A., Hagen, E. V. D., & Jones, C. R. G. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.897015 · Cited by 49
Wang, Q., Hu, Y., Shi, D., Zhang, Y., Zou, X., Li, S., Fang, F., & Yi, L. (2018) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-018-3546-5 · Cited by 41
“2014) or to provide rewarding sensory input when in low arousal (Hutt et al. 1964; Lovaas et al. 1987; McCormick et al. 2014; Sinha et al. 2014).”
BackgroundInfluentialCerullo, S., Fulceri, F., Muratori, F., & Contaldo, A. (2021) · Brain and Cognition · doi:10.1016/j.bandc.2021.105693 · Cited by 42
Pathological alterations in striatal compartments in the human brain of autism spectrum disorder
Kuo, H., & Liu, F. (2020) · Molecular Brain · doi:10.1186/s13041-020-00624-2 · Cited by 39
Identifying the signature of prospective motor control in children with autism
Cavallo, A., Romeo, L., Ansuini, C., Battaglia, F. M., Nobili, L., Pontil, M., Panzeri, S., & Becchio, C. (2021) · Scientific Reports · doi:10.1038/s41598-021-82374-2 · Cited by 42
Epigenetic Treatment of Neuropsychiatric Disorders: Autism and Schizophrenia
Moos, W. H., Maneta, E., Pinkert, C. A., Irwin, M. H., Hoffman, M. E., Faller, D. V., & Steliou, K. (2016) · Drug Development Research · doi:10.1002/ddr.21295 · Cited by 41
“…Rzhetsky et al., 2014; Loke et al., 2015; Raz et al., 2015; Sampson and Mazmanian, 2015] and to identify reliable diagnostic biomarkers and treatment options [Walsh et al., 2011; Veenstra-VanderWeele and Blakely, 2012; Goldani et al., 2014; Sinha et al., 2014; Ali et al., 2015; Anderson, 2015].”
BackgroundTam, F. I., King, J. A., Geisler, D., Korb, F. M., Sareng, J., Ritschel, F., Steding, J., Albertowski, K. U., Roessner, V., & Ehrlich, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-14097-2 · Cited by 38
Structural Covariance of Sensory Networks, the Cerebellum, and Amygdala in Autism Spectrum Disorder
Cardon, G. J., Hepburn, S., & Rojas, D. C. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00615 · Cited by 39
“, prediction errors) could lead to sensory stimulation being perceived as strange, unpleasant, surprising, and/or overwhelming (16, 29, 86, 87).”
BackgroundPriors Bias Perceptual Decisions in Autism, But Are Less Flexibly Adjusted to the Context
Sapey‐Triomphe, L., Timmermans, L., & Wagemans, J. P. (2020) · Autism Research · doi:10.1002/aur.2452 · Cited by 38
“Several theories propose that the symptoms encountered in ASD could be due to an atypical functioning of the predictive brain [Brock, 2012; Palmer, Lawson, & Hohwy, 2017; Pellicano & Burr, 2012; Sinha et al., 2014; Van de Cruys et al., 2014].”
BackgroundWilson, A. C., & Bishop, D. (2020) · Autism Research · doi:10.1002/aur.2345 · Cited by 37
“Pulling together the threads discussed here, there seemed to be cognitive differences in how autistic people responded to and made predictions based on uncertainty (see Sinha, Kjelgaard, Gandhi, Tsourides, & Cardinaux, 2014 for a review of the role of prediction in autism).”
BackgroundNeural correlates of hierarchical predictive processes in autistic adults
Sapey-Triomphe, L.-A., Pattyn, L., Weilnhammer, V., Sterzer, P., & Wagemans, J. (2023) · Nature Communications · doi:10.1038/s41467-023-38580-9 · Cited by 35
Chen, X., Saiyin, H., Liu, Y., Wang, Y., Li, X., Ji, R., & Ma, L. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001868 · Cited by 38
The Role of Dyadic Coordination in Organizing Visual Attention in 5‐Month‐Old Infants
Mason, G. M., Kirkpatrick, F., Schwade, J. A., & Goldstein, M. H. (2018) · Infancy · doi:10.1111/infa.12255 · Cited by 34
Prediction learning in adults with autism and its molecular correlates
Sapey‐Triomphe, L., Temmerman, J., Puts, N. A. J., & Wagemans, J. P. (2021) · Molecular Autism · doi:10.1186/s13229-021-00470-6 · Cited by 38
Kim, Y., Kadlaskar, G., Keehn, R. M., & Keehn, B. (2022) · Autism Research · doi:10.1002/aur.2820 · Cited by 35
“Predictive coding accounts have been used to explain these differences in responding to repeated sensory input in individuals with ASD (e.g., Lawson et al., 2014; Pellicano & Burr, 2012; Sinha et al., 2014; Van de Cruys et al., 2014), and the LC-NE system has been hypothesized to play an important role in predictive c…”
BackgroundMethodFavre, M., Mendola, D. L., Meystre, J., Christodoulou, D., Cochrane, M. J., Markram, H., & Markram, H. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00127 · Cited by 40
“In parallel, an increasing body of evidence suggests that the autistic brain processes surprising events and novel sensory stimuli in an unusual way (Markram andMarkram, 2010; Gomot and Wicker, 2012; Zikopoulos and Barbas, 2013; Sinha et al., 2014).”
BackgroundVicarious Effort-Based Decision-Making in Autism Spectrum Disorders
Mosner, M. G., Kinard, J. L., McWeeny, S., Shah, J. S., Markiewitz, N., Damiano, C. R., Burchinal, M., Rutherford, H. J. V., Greene, R. K., Treadway, M. T., et al. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3220-3 · Cited by 38
“A common trait of individuals with ASD is intolerance of uncertainty or unpredictability, particularly in social contexts, which may reflect underlying impairment in predictive abilities (Sinha et al. 2014).”
Edwards, L. A., Wagner, J., Tager-Flusberg, H. B., & Nelson, C. A. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3222-1 · Cited by 36
“One unifying theory of autism even posits that the disorder may be due to impairments in predictive abilities (Sinha et al. 2014), which in turn might be manifested by, or a consequence of, impaired habituation processes, and which may give rise to functional impairments such as the aforementioned language deficits or…”
BackgroundBeker, S., Foxe, J. J., & Molholm, S. (2021) · Journal of Neurophysiology · doi:10.1152/jn.00329.2021 · Cited by 35
Theory of mind for processing unexpected events across contexts
Dungan, J. A., Stepanovic, M., & Young, L. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw032 · Cited by 40
Landa, R. J., Haworth, J. L., & Nebel, M. B. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00721 · Cited by 36
“Also, these findings are consistent with the hypothesis of predictive impairment in autism which attempts to explain autism as a general impairment in information processing (Sinha et al., 2014) and predicts that motor anticipation will be reduced in individuals with ASD.”
ResultGanglmayer, K., Schuwerk, T., Sodian, B., & Paulus, M. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-03964-8 · Cited by 33
Merchie, A., & Gomot, M. (2023) · Brain Sciences · doi:10.3390/brainsci13071110 · Cited by 40
“In autism there is a reduced ability to predict events and this could lead to deficits in understanding surroundings, which could explain difficulties in coping and may explain the emphasis on sameness, sensory hypersensitivities, difficulties in interacting with dynamic objects as well as difficulties in social cogni…”
BackgroundIncreased reward value of non-social stimuli in children and adolescents with autism
Watson, K. K., Miller, S., Hannah, E., Kovac, M., Damiano, C. R., DiCriscio, A. S., Turner‐Brown, L., Sasson, N. J., Platt, M. L., & Dichter, G. S. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01026 · Cited by 41
“Indeed, recent conceptual models of ASD that highlight deficits in ASD in the ability to process unexpected or unpredictable eventsmay depend on the use of dynamic stimuli to elicit social impairments inASD in the laboratory setting (Sinha et al., 2014; Van de Cruys et al., 2014).”
BackgroundInfluentialSocial and nonsocial visual prediction errors in autism spectrum disorder
Greene, R. K., Zheng, S., Kinard, J. L., Mosner, M. G., Wiesen, C. A., Kennedy, D. P., & Dichter, G. S. (2019) · Autism Research · doi:10.1002/aur.2090 · Cited by 33
“A recent conceptualization of autism spectrum disorder (ASD) is that deficits in predictive ability contribute to core ASD traits [Sinha et al., 2014; Van de Cruys et al., 2014].”
BackgroundResultInfluentialCerebellum and Emotion Processing
Baumann, O., & Mattingley, J. B. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-99550-8_3 · Cited by 39
Predictable Events Enhance Word Learning in Toddlers
Benitez, V. L., & Saffran, J. R. (2018) · Current Biology · doi:10.1016/j.cub.2018.06.017 · Cited by 35
“Predictive processes play an important role in learning in many domains [1, 3, 4, 7], and recent proposals link disrupted predictive processes to developmental disabilities [17, 18].”
Intact predictive processing in autistic adults: evidence from statistical learning
Pesthy, O., Farkas, K., Sapey‐Triomphe, L., Guttengéber, A., Komoróczy, E., Janacsek, K., Réthelyi, J., & Németh, D. (2023) · Scientific Reports · doi:10.1038/s41598-023-38708-3 · Cited by 34
“We screened ASD participants for comorbid disorders: 12 of them had at least one of the following: attention deficit hyperactivity disorder (5), obsessive–compulsive disorder (3), generalized anxiety disorder (2), bipolar disorder (1), depression (1), and schizophrenia (1).”
BackgroundSchwarzlose, R. F., Tillman, R., Hoyniak, C. P., Luby, J. L., & Barch, D. M. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.09.004 · Cited by 38
“This possibility converges with an existing proposal that atypical sensory prediction causes SOR in autism (76).”
BackgroundDorsal striatum dopamine oscillations: Setting the pace of food anticipatory activity
de Lartigue, G., & McDougle, M. J. (2018) · Acta Physiologica · doi:10.1111/apha.13152 · Cited by 33
“Gastric leptin levels fluctuate in response to a meal and make up 20% of circulating leptin.(104) In the small intestine, carbohydrates are sensed by enteroendocrine cells using similar machinery to that found in the oral cavity to detect sweetness, a heterodimer of two G‐protein‐coupled receptors, T1R2 and T1R3.”
BackgroundPredictive sensorimotor control in autism
Arthur, T., Vine, S., Brosnan, M., & Buckingham, G. (2020) · Brain · doi:10.1093/brain/awaa243 · Cited by 29
“Specifically, contrary to simple Bayesian theories of ASD (Pellicano and Burr, 2012; Sinha et al., 2014; Van de Cruys et al., 2014) and evidence of abnormal fronto-cerebellar functioning in the disorder (Fatemi et al.”
BackgroundCosta, A. P., Steffgen, G., & Vögele, C. (2019) · Autism Research · doi:10.1002/aur.2061 · Cited by 34
“, 2017), and impaired predictive abilities (Sinha et al., 2014).”
Rational inattention and tonic dopamine
Mikhael, J. G., Lai, L., & Gershman, S. J. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1008659 · Cited by 34
“This theory has been used to explain behavioral aspects of DA-related 114 pathologies such as autism [81–84], schizophrenia [85–87], and Parkinson’s disease [41].”
MethodKról, M. E., & Król, M. K. (2019) · Autism Research · doi:10.1002/aur.2133 · Cited by 30
“Attenuated priors could explain some of the puzzling features of autistic perception, such as decreased susceptibility to some illusions, enhanced perceptual sensitivity, or insistence on sameness [Sinha et al., 2014].”
BackgroundPerceptual category learning in autism spectrum disorder: Truth and consequences
Mercado, E., Chow, K., Church, B. A., & Lopata, C. J. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.08.016 · Cited by 33
“If infants and toddlers respond to sensorimotor patterns in idiosyncratic ways, then the unique qualities of their experiences may lead them to develop divergent representations that could influence how they perceive and categorize actions (Bertenthal, 1996; Cook, Blakemore, & Press, 2013; Donnellan, Hill, & Leary, 20…”
BackgroundDiagnostic Assessment Techniques and Non-Invasive Biomarkers for Autism Spectrum Disorder
Tanu, T., & Kakkar, D. (2019) · International Journal of E-Health and Medical Communications · doi:10.4018/ijehmc.2019070105 · Cited by 28
The stability flexibility tradeoff and the dark side of detail
Nassar, M. R., & Troiani, V. (2020) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-020-00848-8 · Cited by 30
“Consistent with a prominent theory of autism (Sinha et al., 2014), similar conclusions have been made about autistic individuals under some conditions (Lawson, Mathys, & Rees, 2017), although other studies have failed to identify differences between autistic individuals and controls (Manning, Kilner, Neil, Karaminis,…”
ResultAn internal model for canceling self-generated sensory input in freely behaving electric fish
Wallach, A., & Sawtell, N. B. (2023) · Neuron · doi:10.1016/j.neuron.2023.05.019 · Cited by 26
Visual motion prediction and verbal false memory performance in autistic children
Tewolde, F. G., Bishop, D. V. M., & Manning, C. (2018) · Autism Research · doi:10.1002/aur.1915 · Cited by 25
“We also predicted that autistic children would show particular difficulties when required to extrapolate over longer occlusion durations [Sinha et al., 2014].”
BackgroundResultInfluentialCerebellar Contributions to Social Cognition in ASD: A Predictive Processing Framework
Frosch, I. R., Mittal, V. A., & D’Mello, A. M. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.810425 · Cited by 28
Xie, F., Pascual, E., & OAKLEY, T. V. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1010615 · Cited by 27
“Their anticipating the experimenter’s questions also seems to indicate that autism may not be a disorder of prediction, as has been suggested (Sinha et al., 2014), or not too severely or at all levels.”
BackgroundButti, N., Biffi, E., Genova, C., Romaniello, R., Redaelli, D. F., Reni, G., Borgatti, R., & Urgesi, C. (2020) · Trials · doi:10.1186/s13063-019-4001-4 · Cited by 28
Mechanisms for the Approach/Avoidance Decision Applied to Autism
Pfaff, D., & Barbas, H. (2019) · Trends in Neurosciences · doi:10.1016/j.tins.2019.05.002 · Cited by 26
Color Afterimages in Autistic Adults
Maule, J., Stanworth, K., Pellicano, E., & Franklin, A. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2786-5 · Cited by 26
“We used the nulling method as described by Lupyan (2015) to investigate two hypotheses related to the hypopriors account of autism (Pellicano and Burr 2012) and other predictive coding accounts (Friston et al. 2013; Lawson et al. 2014; Sinha et al. 2014; Van de Cruys et al. 2013).”
BackgroundMethodPredictive language processing in young autistic children
Prescott, K. E., Mathée‐Scott, J., Reuter, T., Edwards, J., Saffran, J. R., & Weismer, S. E. (2022) · Autism Research · doi:10.1002/aur.2684 · Cited by 27
“…a mechanism which contributes to language processing ability in NT development (e.g., Mani & Huettig, 2012), has been proposed by several researchers in recent theoretical accounts as a domain-general impairment in ASD (e.g., Gomot & Wicker, 2012; Sinha et al., 2014; Van de Cruys et al., 2014).”
BackgroundResultInfluentialAmoruso, L., Finisguerra, A., & Urgesi, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-33827-8 · Cited by 29
Siciliano, L., & Clausi, S. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.00096 · Cited by 28
“, 2017), mainly associated with a general impairment of the predictive process (Sinha et al., 2014).”
BackgroundSchadenberg, B. R., Reidsma, D., Heylen, D., & Evers, V. (2021) · ACM Transactions on Human-Robot Interaction · doi:10.1145/3461534 · Cited by 29
“For instance, deviations in the prediction mechanism in the brain have been linked to explaining autism spectrum conditions [54, 72, 90, 99], delusions and hallucination in schizophrenia [18, 35] and depression [49].”
BackgroundResultTye, C., Bedford, R., Asherson, P. J., Ashwood, K. L., Azadi, B., Bolton, P., & McLoughlin, G. (2017) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2017.06.002 · Cited by 28
Venkataraman, A., Yang, D. Y.-J., Dvornek, N., Staib, L. H., Duncan, J. S., Pelphrey, K. A., & Ventola, P. (2016) · NeuroReport · doi:10.1097/wnr.0000000000000662 · Cited by 24
Adolescents with autism show typical fMRI repetition suppression, but atypical surprise response
Utzerath, C., Schmits, I. C., Buitelaar, J., & de Lange, F. P. (2018) · Cortex · doi:10.1016/j.cortex.2018.08.019 · Cited by 23
Toward a Phenomenological Account of Embodied Subjectivity in Autism
Boldsen, S. (2018) · Culture Medicine and Psychiatry · doi:10.1007/s11013-018-9590-y · Cited by 25
Contextual Priors Guide Perception and Motor Responses to Observed Actions
Betti, S., Finisguerra, A., Amoruso, L., & Urgesi, C. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab241 · Cited by 25
Olivito, G., Siciliano, L., Clausi, S., Lupo, M., Baiocco, R., Gragnani, A., Saettoni, M., Chiaie, R. D., Laghi, F., & Leggio, M. G. (2023) · Biomedicines · doi:10.3390/biomedicines11020309 · Cited by 26
Wada, M., Hayashi, K., Seino, K., Ishii, N., Nawa, T., & Nishimaki, K. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1077542 · Cited by 32
A theory of autism bridging across levels of description
Noel, J., & Angelaki, D. E. (2023) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2023.04.010 · Cited by 27
“ASD has been described as a disorder of prediction [15,16,91], and, just as causal inference and divisive normalization may, respectively, be canonical computations at a behavioral and algorithmic level, predictive coding has been described as a basic computational and neural motif [92].”
Ciricugno, A., Oldrati, V., Cattaneo, Z., Leggio, M. G., Urgesi, C., & Olivito, G. (2024) · The Cerebellum · doi:10.1007/s12311-023-01652-z · Cited by 24
“…the ability to make accurate predictions in both social and non-social domains is impacted in autism spectrum disorder (ASD) patients [127, 128], who also show impaired ability to make predictions about their internal state [129], likely due to cerebellar structural and functional…”
BackgroundGranovetter, M. C., Burlingham, C. S., Blauch, N. M., Minshew, N. J., Heeger, D. J., & Behrmann, M. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.2680-19.2020 · Cited by 25
“, 2010), thereby hampering the establishment of priors and the ability to learn from novel environmental input (Sinha et al., 2014; Dinstein et al., 2015).”
BackgroundMamashli, F., Kozhemiako, N., Khan, S., Nunes, A. S., McGuiggan, N. M., Losh, A., Joseph, R. M., Ahveninen, J., Doesburg, S. M., Hämäläinen, M., et al. (2021) · Autism Research · doi:10.1002/aur.2497 · Cited by 24
“…multiple reports of abnormalities in top-down processing in ASD (Cook et al., 2012; Frith, 2004; Gomot & Wicker, 2012; Khan et al., 2015; Mamashli et al., 2017; Neumann et al., 2006; Seymour et al., 2019; Sinha et al., 2014), including during face processing (Leung et al., 2014; Loth et al., 2010).”
BackgroundInfluentialEwbank, M., Hagen, E. V. D., Powell, T. E., Henson, R. N., & Calder, A. J. (2015) · Cortex · doi:10.1016/j.cortex.2015.10.011 · Cited by 22
“Impairments in prediction have also been proposed to underlie other non-social and social symptoms found in autism (Sinha et al., 2014).”
Ego, C., Bonhomme, L., de Xivry, J. O., Fonséca, D. D., Lefèvre, P., Masson, G. S., & Deruelle, C. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2016.08.021 · Cited by 23
“They argue against a recent and popular hypothesis that views autism as a general deficit of prediction mechanisms (e.g., Gomot and Wicker, 2012; Pellicano and Burr, 2012; Sinha et al., 2014).”
Grisoni, L., Moseley, R. L., Motlagh, S., Kandia, D., Sener, N., Pulvermüller, F., Roepke, S., & Mohr, B. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2019.00395 · Cited by 21
“Perceptual-motor-sensory, and social difficulties in ASD have been explained on the basis of compromised adaptation due to lack of predictability of environmental stimuli (Baron-Cohen, 2009; Pellicano and Burr, 2012; Sinha et al., 2014).”
BackgroundMethodIncreased influence of prior choices on perceptual decisions in autism
Feigin, H., Shalom-Sperber, S., Zachor, D. A., & Zaidel, A. (2021) · eLife · doi:10.7554/elife.61595 · Cited by 22
Rossel, P., Peyrin, C., Roux-Sibilon, A., & Kauffmann, L. (2022) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037/xhp0000993 · Cited by 25
“56 PRIOR SCENE KNOWLEDGE INCREASES ITS PERCEIVED SHARPNESS insufficient or excessive influence of expectations on perception, respectively (e.g., Pellicano & Burr, 2012; Powers et al., 2017; Sinha et al., 2014; Teufel et al., 2015; Van de Cruys et al., 2014).”
BackgroundJacques, C., Courchesne, V., Mineau, S., Dawson, M., & Mottron, L. (2022) · Autism · doi:10.1177/13623613211068221 · Cited by 25
“Current deficit-based autism criteria and theories invoking insistence on sameness, inflexibility (extreme distress in response to changes, difficulties with transitions; APA, 2013), sensory hypersensitivity, sensory dysfunction, and/or sensory overload (Pellicano, 2013; Simmons, 2019; Sinha et al., 2014; Van de Cruys…”
BackgroundLassen, J., Oranje, B., Vestergaard, M. D., Foldager, M., Kjær, T. W., Arnfred, S., & Aggernæs, B. (2022) · Autism Research · doi:10.1002/aur.2738 · Cited by 29
“The predictive coding framework has gained increasing traction as a way to explain the core symptoms of autism (Lawson et al., 2014; Sinha et al., 2014; Van de Cruys et al., 2014).”
BackgroundCortical speech tracking is related to individual prediction tendencies
Schubert, J., Schmidt, F., Gehmacher, Q., Bresgen, A., & Weisz, N. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhac528 · Cited by 22
“We propose that this tendency can even be conceptualized as a “trait-like” disposition, following a notion that has already been used to explain clinical psychological conditions and disorders such as autism (Sinha et al. 2014), schizophrenia (Sterzer et al.”
BackgroundMethodInfluentialSocial Knowledge & Performance in Autism: A Critical Review & Recommendations
Gates, J. A., McNair, M. L., Richards, J. K., & Lerner, M. D. (2023) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-023-00449-0 · Cited by 30
Huang, Q., Velthuis, H., Pereira, A. C., Ahmad, J., Cooke, S. F., Ellis, C. L., Ponteduro, F. M., Puts, N. A. J., Dimitrov, M., Batallé, D., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02619-8 · Cited by 26
“Arbaclofen is the active right enantiomer of baclofen with >100 fold speci fi city for GABA B receptor compared to the ‘ S ’ enantiomer and approximately fi ve times greater speci fi city than racemic baclofen [81].”
BackgroundAction prediction in 10-month-old infants at high and low familial risk for Autism Spectrum Disorder
Braukmann, R., Ward, E. K., Hessels, R. S., Harold Bekkering, A., Buitelaar, J. K., & Hunnius, S. (2018) · Research in Autism · doi:10.1016/j.rasd.2018.02.004 · Cited by 24
“In older children and adults with ASD, prediction di ffi culties have been reported in multiple studies (Boria et al., 2009; Cattaneo et al., 2007; Schuwerk et al., 2016; Zalla et al., 2010) and atypical predictive processing is a proposed underlying mechanism of the disorder (Cruys et al., 2014; Lawson et al., 2014; Pe…”
InfluentialKim, T.-K., Chaloner, F. A., Cooke, S. F., Harnett, M. T., & Bear, M. F. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00555 · Cited by 21
Hallett, V., Mueller, J., Breese, L., Hollett, M., Beresford, B., Irvine, A. L., Pickles, A. R., Slonims, V., Scott, S., Charman, T., et al. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04442-2 · Cited by 26
Anteraper, S. A., Guell, X., Hollinshead, M. O., D’Mello, A. M., Whitfield, S., Biederman, J., & Joshi, G. (2020) · Brain Connectivity · doi:10.1089/brain.2020.0746 · Cited by 25
“A large and expanding body of evidence indicates that the cerebellum is involved in prediction (Sokolov et al., 2017), and recent work suggests that individuals with ASDs have prediction deficits (Sinha et al., 2014).”
Sport and Autism: What Do We Know so Far? A Review
Grosprêtre, S., Ruffino, C., Derguy, C., & Gueugneau, N. (2024) · Sports Medicine - Open · doi:10.1186/s40798-024-00765-x · Cited by 34
“Additional issues in maintaining balance and motion planning were also generally reported [23, 24].”
BackgroundLocal and long-range circuit elements for cerebellar function
Xiao, L., & Scheiffele, P. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.12.016 · Cited by 22
Strengthening risk prediction using statistical learning in children with autism spectrum disorder
Tanu, T., & Kakkar, D. (2018) · Advances in Autism · doi:10.1108/aia-06-2018-0022 · Cited by 21
Autism Spectrum Disorder: A Neuro-Immunometabolic Hypothesis of the Developmental Origins
Frasch, M. G., Yoon, B.-J., Helbing, D. L., Snir, G., Antonelli, M. C., & Bauer, R. (2023) · Biology · doi:10.3390/biology12070914 · Cited by 21
“In an attempt to tie this wealth of data together conceptually in a unified model, a unified model of autism has been proposed [48].”
BackgroundZhou, H., Cui, X., Yang, B., Shi, L., Luo, X., Cheung, E. F. C., Lui, S. S. Y., & Chan, R. C. K. (2021) · Clinical Psychological Science · doi:10.1177/21677026211031543 · Cited by 21
Schadenberg, B. R., Reidsma, D., Evers, V., Davison, D. P., Li, J. J., Heylen, D., Neves, C., Alvito, P., Shen, J., Pantić, M., et al. (2021) · ACM Transactions on Computer-Human Interaction · doi:10.1145/3468849 · Cited by 23
“…to frequently experience these mismatches between predicted and observed sensory information due to a decreased influence of predictions on perception, which is hypothesised in current Bayesian accounts of autism to be at the heart of their condition [31, 81, 104, 135], [see 100, for a review].”
BackgroundGenetics, molecular control and clinical relevance of habituation learning
Blok, L. E. R., Boon, M., van Reijmersdal, B., Höffler, K. D., Fencková, M., & Schenck, A. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104883 · Cited by 23
Robust odor identification in novel olfactory environments in mice
Li, Y., Swerdloff, M., She, T., Rahman, A., Sharma, N. K., Shah, R., Castellano, M., Mogel, D., Wu, J. H. Y., Ahmed, A. A., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36346-x · Cited by 23
Ensemble perception of color in autistic adults
Maule, J., Stanworth, K., Pellicano, E., & Franklin, A. (2016) · Autism Research · doi:10.1002/aur.1725 · Cited by 25
“The attenuated priors account has been followed by other predictive coding theories of autism [e.g., Lawson, Rees, & Friston, 2014; Sinha et al., 2014; van Boxtel & Lu, 2013; Van de Cruys, de-Wit, Evers, Boets, & Wagemans, 2013].”
MethodPrediction error neurons in mouse cortex are molecularly targetable cell typesPreprint
O'Toole, S. M., Oyibo, H. K., & Keller, G. B. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.20.500837 · Cited by 21
Cakar, M. E., Okada, N. J., Cummings, K. K., Jung, J., Bookheimer, S. Y., Dapretto, M., & Green, S. A. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1337921 · Cited by 24
Decreased amplitude and reliability of odor-evoked responses in two mouse models of autism
Geramita, M. A., Wen, J. A., Rannals, M. D., & Urban, N. N. (2019) · Journal of Neurophysiology · doi:10.1152/jn.00277.2019 · Cited by 20
“…increased neural variability has been proposed as an explanation for deficits in visual perception (Dakin and Frith 2005; Simmons et al. 2009) and in predicting the local environment (Lawson et al. 2014; Pellicano and Burr 2012; Sinha et al. 2014; Van de Cruys et al. 2014) in individuals with ASD.”
BackgroundAutistic Traits Differently Account for Context-Based Predictions of Physical and Social Events
Bianco, V., Finisguerra, A., Betti, S., D’Argenio, G., & Urgesi, C. (2020) · Brain Sciences · doi:10.3390/brainsci10070418 · Cited by 19
“Beside the other manifestations of this disorder, including social withdrawal and isolation [2], the presence of sensory abnormalities [3] and difficulties in mentalizing processes [4], it has been repeatedly shown that individuals with ASD struggle with making predictions or with deciding what to pay attention to on…”
BackgroundLow-level, prediction-based sensory and motor processes are unimpaired in Autism
Finnemann, J., Plaisted-Grant, K. C., Moore, J. W., Teufel, C., & Fletcher, P. C. (2021) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2021.107835 · Cited by 22
Miller, I. T., Miller, C. S., Wiederhold, M. D., & Wiederhold, B. K. (2020) · Autism in Adulthood · doi:10.1089/aut.2019.0076 · Cited by 19
“24 Difficulties discerning salient contextual information increase the likelihood that environmental stimuli ‘‘flood’’ sensory processing centers and elicit stress or anxiety.”
Autonomic and Electrophysiological Evidence for Reduced Auditory Habituation in Autism
Gandhi, T. K., Tsourides, K., Singhal, N., Cardinaux, A. L., Jamal, W., Pantazis, D., Kjelgaard, M., & Sinha, P. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04636-8 · Cited by 21
Self-citationDifficulties predicting time-to-arrival in individuals with autism spectrum disorders
Sheppard, E., van Loon, E. M., Underwood, G., & Ropar, D. (2016) · Research in Autism · doi:10.1016/j.rasd.2016.05.001 · Cited by 19
van Noordt, S. J. R., Wu, J., Venkataraman, A., Larson, M. J., South, M., & Crowley, M. J. (2017) · Research in Autism · doi:10.1016/j.rasd.2017.01.011 · Cited by 21
“Impairment in appreciation for choice outcomes could contribute to several core symptoms of ASD (Sinha et al., 2014).”
Neurocognitive Mechanisms of Social Inferences in Typical and Autistic Adolescents
Rosenblau, G., Korn, C. W., Dutton, A. J., Lee, D., & Pelphrey, K. A. (2020) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2020.07.002 · Cited by 26
Daikoku, T., Wiggins, G. A., & Nagai, Y. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.640412 · Cited by 17
Metadata
- Authors
- Sinha, P., Kjelgaard, M. M., Gandhi, T. K., Tsourides, K., Cardinaux, A. L., Pantazis, D., Diamond, S. P., & Held, R. M.
- Affiliations
- Massachusetts Institute of Technology (US)
- MGH Institute of Health Professions (US)
- Defence Institute of Physiology and Allied Sciences (IN)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2014-10-06
- Volume
- 111
- Issue
- 42
- Pages
- 15220-15225
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC4210351
- OpenAlex
- W2088415689
- Cited by
- 563
- References
- 119
- Citations by year
- 2026: 43 · 2025: 47 · 2024: 48 · 2023: 67 · 2022: 47 · 2021: 79 · 2020: 56 · 2019: 41 · 2018: 38 · 2017: 40 · 2016: 36 · 2015: 20
- FWCI
- 17.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Keywords
- autism spectrum disorder, prediction, predictive processing, autism phenotype, theory of mind, social cognition, diagnostic biomarkers, autism treatment
- MeSH terms
- Autistic Disorder, Basal Ganglia, Cerebellum, Cognition, Corpus Striatum, Humans, Infant, Language, Markov Chains, Models, Theoretical, Neuronal Plasticity, Phenotype, Probability, Social Behavior, Time Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
A language model drew the claims from the paper on 2026-10-05, under version 3 of the claim definition (model deepseek-v4.1-flash, prompt extract-v3).
A second model labelled each claim on 2026-10-05 (model jev-1.13-20260917, definition revision gold-guideline-v0.2).
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
