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Cited by 1,238

The DOI matches its Crossref record; 166 of the 166 references it cites were found in a registry or an index.

Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Pediatric Thyroid Cancer

Open access
Francis, Gary L., Waguespack, Steven G., Bauer, Andrew J., Angelos, Peter, Benvenga, Salvatore, Cerutti, Janete M., Dinauer, Catherine A., Hamilton, Jill, Hay, Ian D., Luster, Markus, Parisi, Marguerite T., Rachmiel, Marianna, Thompson, Geoffrey B., Yamashita, Shunichi·2015·Thyroid
DOI 10.1089/thy.2014.0460
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Abstract

BACKGROUND: Previous guidelines for the management of thyroid nodules and cancers were geared toward adults. Compared with thyroid neoplasms in adults, however, those in the pediatric population exhibit differences in pathophysiology, clinical presentation, and long-term outcomes. Furthermore, therapy that may be recommended for an adult may not be appropriate for a child who is at low risk for death but at higher risk for long-term harm from overly aggressive treatment. For these reasons, unique guidelines for children and adolescents with thyroid tumors are needed. METHODS: A task force commissioned by the American Thyroid Association (ATA) developed a series of clinically relevant questions pertaining to the management of children with thyroid nodules and differentiated thyroid cancer (DTC). Using an extensive literature search, primarily focused on studies that included subjects ≤18 years of age, the task force identified and reviewed relevant articles through April 2014. Recommendations were made based upon scientific evidence and expert opinion and were graded using a modified schema from the United States Preventive Services Task Force. RESULTS: These inaugural guidelines provide recommendations for the evaluation and management of thyroid nodules in children and adolescents, including the role and interpretation of ultrasound, fine-needle aspiration cytology, and the management of benign nodules. Recommendations for the evaluation, treatment, and follow-up of children and adolescents with DTC are outlined and include preoperative staging, surgical management, postoperative staging, the role of radioactive iodine therapy, and goals for thyrotropin suppression. Management algorithms are proposed and separate recommendations for papillary and follicular thyroid cancers are provided. CONCLUSIONS: In response to our charge as an independent task force appointed by the ATA, we developed recommendations based on scientific evidence and expert opinion for the management of thyroid nodules and DTC in children and adolescents. In our opinion, these represent the current optimal care for children and adolescents with these conditions.

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Metadata

Authors
Francis, G. L., Waguespack, S. G., Bauer, A. J., Angelos, P., Benvenga, S., Cerutti, J. M., Dinauer, C. A., Hamilton, J., Hay, I. D., Luster, M., Parisi, M. T., Rachmiel, M., Thompson, G. B., & Yamashita, S.
Venue
Thyroid
Publisher
SAGE Publications
Published
2015-07
Volume
25
Issue
7
Pages
716-759
ISSN
  • 1050-7256 (ISSN-L)
  • 1557-9077
DOI
10.1089/thy.2014.0460
OpenAlex
W2314815360
Cited by
1,238
References
166
FWCI
65.82
Type
journal article
Language
en
Open access
hybrid

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