Cited by 317Food composition and propertiesNutritional Studies and DietDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 50 of the 51 references it cites were found in a registry or an index.

The effects of a whole grain–enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome

Open access

Katcher, Heather I, Legro, Richard S, Kunselman, Allen R, Gillies, Peter J, Demers, Laurence M, Bagshaw, Deborah M, Kris-Etherton, Penny M·2008·The American Journal of Clinical Nutrition

DOI 10.1093/ajcn/87.1.79

Open this paper in CoChat — free account

Abstract

Background Whole-grain foods are associated in observational studies with a lower body mass index and lower cardiovascular disease (CVD) risk. However, few clinical trials have tested whether incorporating whole grains into a hypocaloric diet increases weight loss and improves CVD risk factors.Objective The aim of this study was to determine whether including whole-grain foods in a hypocaloric (reduced by 500 kcal/d) diet enhances weight loss and improves CVD risk factors.Design Obese adults (25 M, 25 F) with metabolic syndrome were randomly assigned to receive dietary advice either to avoid whole-grain foods or to obtain all of their grain servings from whole grains for 12 wk. All participants were given the same dietary advice in other respects for weight loss.Results Body weight, waist circumference, and percentage body fat decreased significantly (P<0.001) in both groups over the study period, but there was a significantly (P=0.03) greater decrease in percentage body fat in the abdominal region in the whole-grain group than in the refined-grain group. C-reactive protein (CRP) decreased 38% in the whole-grain group independent of weight loss but was unchanged in the refined-grain group (P=0.01 for group x time interaction). Total, LDL, and HDL cholesterol decreased in both diet groups (P<0.05). Dietary fiber and magnesium intakes increased in the whole-grain but not the refined-grain group (P=0.007 and P<0.001, respectively, for group x time interaction).Conclusions Both hypocaloric diets were effective means of improving CVD risk factors with moderate weight loss. There were significantly (P<0.05) greater decreases in CRP and percentage body fat in the abdominal region in participants consuming whole grains than in those consuming refined grains.

Integrity signals

Registry

Crossref · 10.1093/ajcn/87.1.79

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423
Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944
Self-citation
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011
Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961
Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The evidence report
(1998) · PsycEXTRA Dataset · doi:10.1037/e565682010-001 · Cited by 9,453
Random-Effects Models for Longitudinal Data
Laird, N. M., & Ware, J. H. (1982) · Biometrics · doi:10.2307/2529876 · Cited by 8,923
Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp
Matsuda, M., & DeFronzo, R. A. (1999) · Diabetes Care · doi:10.2337/diacare.22.9.1462 · Cited by 5,621
Small sample inference for fixed effects from restricted maximum likelihood
Kenward, M. G., & Roger, J. H. (1997) · Biometrics · doi:10.2307/2533558 · Cited by 4,552
Effect of a Mediterranean-Style Diet on Endothelial Dysfunction and Markers of Vascular Inflammation in the Metabolic Syndrome: A Randomized Trial
Esposito, K., Marfella, R., Ciotola, M., Di Palo, C., Giugliano, F., Giugliano, G., D'Armiento, M., D'Andrea, F., & Giugliano, D. (2004) · JAMA · doi:10.1001/jama.292.12.1440 · Cited by 2,126
Untitled work
Bantle (2008) · doi:10.2337/dc08-s061 · Cited by 1,795

Show all 51 references

Research works printed but not linked: 2

2007, Diabetes Care, 30, S48
Ello-Martin, 2004, Measuring diet satisfaction: the development of a reliable assessment tool., Obes Res, 12, A93

Sorted by citations

Dietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098
Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies
Aune, D., Keum, N., Giovannucci, E., Fadnes, L. T., Boffetta, P., Greenwood, D. C., Tonstad, S., Vatten, L. J., Riboli, E., & Norat, T. (2016) · BMJ · doi:10.1136/bmj.i2716 · Cited by 1,013
The Mediterranean Diet, its Components, and Cardiovascular Disease
Widmer, R. J., Flammer, A. J., Lerman, L. O., & Lerman, A. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.10.014 · Cited by 963
“A smaller RCT showed beneficial effects on BMI and waist circumference in the group randomized to hypocaloric whole grains as opposed to hypocaloric refined grains.(80) Moreover, the group obtaining all carbohydrates from whole grains for 12 weeks had significant improvements in C-reactive protein levels and cholester…”
Background
Australian Dietary Guidelines
Curriculum, K. (2006) · Cited by 768
Whole grain and refined grain consumption and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of cohort studies
Aune, D., Norat, T., Romundstad, P., & Vatten, L. J. (2013) · European Journal of Epidemiology · doi:10.1007/s10654-013-9852-5 · Cited by 539
Components of a Cardioprotective Diet: New Insights
Mozaffarian, D., Appel, L. J., & Van Horn, L. (2011) · Circulation · doi:10.1161/circulationaha.110.968735 · Cited by 571
Role of diet in type 2 diabetes incidence: umbrella review of meta-analyses of prospective observational studies
Neuenschwander, M., Ballon, A., Weber, K. S., Norat, T., Aune, D., Schwingshackl, L., & Schlesinger, S. (2019) · BMJ · doi:10.1136/bmj.l2368 · Cited by 531
Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
Roager, H. M., Vogt, J. K., Kristensen, M., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., et al. (2017) · Gut · doi:10.1136/gutjnl-2017-314786 · Cited by 447
ERRATUM
(2013) · The Journal of Nutrition · doi:10.3945/jn.111.155325 · Cited by 634
Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses
Korem, T., Zeevi, D., Zmora, N., Weissbrod, O., Bar, N., Lotan-Pompan, M., Avnit-Sagi, T., Kosower, N., Malka, G., Rein, M., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.05.002 · Cited by 318
Whole-grain wheat consumption reduces inflammation in a randomized controlled trial on overweight and obese subjects with unhealthy dietary and lifestyle behaviors: role of polyphenols bound to cereal dietary fiber
Vitaglione, P., Mennella, I., Ferracane, R., Rivellese, A. A., Giacco, R., Ercolini, D., Gibbons, S. M., Storia, A. L., Gilbert, J. A., Jonnalagadda, S. S., et al. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.088120 · Cited by 329
Whole grain and body weight changes in apparently healthy adults: a systematic review and meta-analysis of randomized controlled studies
Pol, K., Christensen, R., Bartels, E. M., Raben, A., Tetens, I., & Kristensen, M. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.064659 · Cited by 272
Putting the Whole Grain Puzzle Together: Health Benefits Associated with Whole Grains—Summary of American Society for Nutrition 2010 Satellite Symposium1–3
Jonnalagadda, S. S., Harnack, L., Liu, R. H., McKeown, N. M., Seal, C. J., Liu, S., & Fahey, G. C., Jr. (2011) · Journal of Nutrition · doi:10.3945/jn.110.132944 · Cited by 272
Greater Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes, Cardiovascular Disease, and Weight Gain
Ye, E. Q., Chacko, S. A., Chou, E. L., Kugizaki, M., & Liu, S. (2012) · Journal of Nutrition · doi:10.3945/jn.113.179473 · Cited by 257
Whole-grain and blood lipid changes in apparently healthy adults: a systematic review and meta-analysis of randomized controlled studies
Hollænder, P. L., Ross, A. B., & Kristensen, M. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.109165 · Cited by 233
Markers of cardiovascular risk are not changed by increased whole-grain intake: the WHOLEheart study, a randomised, controlled dietary intervention
Brownlee, I. A., Moore, C. S., Chatfield, M. D., Richardson, D. P., Ashby, P., Kuznesof, S. A., Jebb, S. A., & Seal, C. J. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510000644 · Cited by 231
Whole Grains and Pulses: A Comparison of the Nutritional and Health Benefits
Rebello, C. J., Greenway, F. L., & Finley, J. W. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf500932z · Cited by 241
Plant Foods, Antioxidant Biomarkers, and the Risk of Cardiovascular Disease, Cancer, and Mortality: A Review of the Evidence
Aune, D. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz042 · Cited by 222
The Dietary Intake of Wheat and other Cereal Grains and Their Role in Inflammation
de Punder, K., & Pruimboom, L. (2013) · Nutrients · doi:10.3390/nu5030771 · Cited by 204
Intake of whole grain foods and risk of type 2 diabetes: results from three prospective cohort studies
Hu, Y., Ding, M., Sampson, L., Willett, W. C., Manson, J. E., Wang, M., Rosner, B., Hu, F. B., & Sun, Q. (2020) · BMJ · doi:10.1136/bmj.m2206 · Cited by 202
Role of Fiber in Cardiovascular Diseases: A Review
Viuda‐Martos, M., López-Marcos, M. C., Fernández‐López, J., Sendra, E., Vargas, J. H. L., & Pérez‐Álvarez, J. Á. (2010) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/j.1541-4337.2009.00102.x · Cited by 200
Whole-Grain Ready-to-Eat Oat Cereal, as Part of a Dietary Program for Weight Loss, Reduces Low-Density Lipoprotein Cholesterol in Adults with Overweight and Obesity More than a Dietary Program Including Low-Fiber Control Foods
Maki, K. C., Beiseigel, J. M., Jonnalagadda, S. S., Gugger, C. K., Reeves, M. S., Farmer, M. V., Kaden, V. N., & Rains, T. M. (2010) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2009.10.037 · Cited by 188
Whole Grain Compared with Refined Wheat Decreases the Percentage of Body Fat Following a 12-Week, Energy-Restricted Dietary Intervention in Postmenopausal Women
Kristensen, M., Toubro, S., Jensen, M. G., Ross, A. B., Riboldi, G., Petronio, M., Bügel, S., Tetens, I., & Astrup, A. V. (2012) · Journal of Nutrition · doi:10.3945/jn.111.142315 · Cited by 179
Association between carbohydrate quality and inflammatory markers: systematic review of observational and interventional studies
Buyken, A. E., Goletzke, J., Joslowski, G., Felbick, A., Cheng, G., Herder, C., & Brand-Miller, J. C. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.074252 · Cited by 180
A whole-grain cereal-rich diet increases plasma betaine, and tends to decrease total and LDL-cholesterol compared with a refined-grain diet in healthy subjects
Ross, A. B., Bruce, S. J., Blondel‐Lubrano, A., Oguey-Araymon, S., Beaumont, M., Bourgeois, A., Nielsen-Moennoz, C., Vigo, M., Fay, L., Kochhar, S., et al. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114510005209 · Cited by 177
Rye phenolics in nutrition and health
Bondia‐Pons, I., Aura, A., Vuorela, S., Kolehmainen, M., Mykkänen, H. M., & Poutanen, K. S. (2009) · Journal of Cereal Science · doi:10.1016/j.jcs.2009.01.007 · Cited by 173
Impact of dietary fiber intake on glycemic control, cardiovascular risk factors and chronic kidney disease in Japanese patients with type 2 diabetes mellitus: the Fukuoka Diabetes Registry
Fujii, H., Iwase, M., Ohkuma, T., Kaizu, S., Ide, H., Kikuchi, Y., Idewaki, Y., Joudai, T., Hirakawa, Y., Uchida, K., et al. (2013) · Nutrition Journal · doi:10.1186/1475-2891-12-159 · Cited by 172
Whole- and refined-grain intakes are differentially associated with abdominal visceral and subcutaneous adiposity in healthy adults: the Framingham Heart Study
McKeown, N. M., Troy, L. M., Jacques, P. F., Hoffmann, U., O’Donnell, C. J., & Fox, C. S. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.29106 · Cited by 151
Food groups and intermediate disease markers: a systematic review and network meta-analysis of randomized trials
Schwingshackl, L., Hoffmann, G., Iqbal, K., Schwedhelm, C., & Boeing, H. (2018) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy151 · Cited by 147
Dietary strategies to reduce metabolic syndrome
Andersen, C. J., & Fernández, M. L. (2013) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-013-9251-y · Cited by 149
Effects of Whole Grains on Coronary Heart Disease Risk
Harris, K. A., & Kris‐Etherton, P. M. (2010) · Current Atherosclerosis Reports · doi:10.1007/s11883-010-0136-1 · Cited by 134
Self-citation
Whole-Grain Intake and Cereal Fiber Are Associated with Lower Abdominal Adiposity in Older Adults , ,
McKeown, N. M., Yoshida, M., Shea, M. K., Jacques, P. F., Lichtenstein, A. H., Rogers, G. T., Booth, S. L., & Saltzman, E. J. (2009) · Journal of Nutrition · doi:10.3945/jn.108.103762 · Cited by 132
A whole-grain cereal-based diet lowers postprandial plasma insulin and triglyceride levels in individuals with metabolic syndrome
Giacco, R., Costabile, G., Pepa, G. D., Anniballi, G., Griffo, E., Mangione, A., Cipriano, P., Viscovo, D., Clemente, G., Landberg, R., et al. (2014) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2014.01.007 · Cited by 127
Whole-grain foods and chronic disease: evidence from epidemiological and intervention studies
Seal, C. J., & Brownlee, I. A. (2015) · Proceedings of The Nutrition Society · doi:10.1017/s0029665115002104 · Cited by 127
Whole-Grain Consumption Is Associated with Diet Quality and Nutrient Intake in Adults: The National Health and Nutrition Examination Survey, 1999-2004
O’Neil, C. E., Nicklas, T. A., Zanovec, M. T., & Cho, S. S. (2010) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2010.07.012 · Cited by 126
Wholegrain vs. refined wheat bread and pasta. Effect on postprandial glycemia, appetite, and subsequent ad libitum energy intake in young healthy adults
Kristensen, M., Jensen, M. G., Riboldi, G., Petronio, M., Bügel, S., Toubro, S., Tetens, I., & Astrup, A. V. (2009) · Appetite · doi:10.1016/j.appet.2009.10.003 · Cited by 130
Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people
Giacco, R., Clemente, G., Cipriano, D. A. M., Luongo, D., Viscovo, D., Patti, L., Marino, L., Giacco, A., Naviglio, D., Bianchi, M. A., et al. (2009) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2009.03.025 · Cited by 124
Effect of Cocoa and Its Flavonoids on Biomarkers of Inflammation: Studies of Cell Culture, Animals and Humans
Goya, L., Martín, M. Á., Sarriá, B., Ramos, S., Mateos, R., & Bravo, L. (2016) · Nutrients · doi:10.3390/nu8040212 · Cited by 123
Dietary habits and behaviors associated with nonalcoholic fatty liver disease
Yasutake, K. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i7.1756 · Cited by 128
Whole grain intake in relation to body weight: From epidemiological evidence to clinical trials
Giacco, R., Pepa, G. D., Luongo, D., & Riccardi, G. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2011.07.003 · Cited by 117
A Whole-Grain Diet Reduces Cardiovascular Risk Factors in Overweight and Obese Adults: A Randomized Controlled Trial
Kirwan, J. P., Malin, S. K., Scelsi, A. R., Kullman, E. L., Navaneethan, S. D., Pagadala, M. R., Haus, J. M., Filion, J., Godin, J., Kochhar, S., et al. (2016) · Journal of Nutrition · doi:10.3945/jn.116.230508 · Cited by 119
Effects of different dietary approaches on inflammatory markers in patients with metabolic syndrome: A systematic review and meta-analysis
Steckhan, N., Hohmann, C.-D., Keßler, C. S., Dobos, G., Michalsen, A., & Cramer, H. (2015) · Nutrition · doi:10.1016/j.nut.2015.09.010 · Cited by 118
How does wheat grain, bran and aleurone structure impact their nutritional and technological properties?
Rosa‐Sibakov, N., Poutanen, K. S., & Micard, V. (2014) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2014.10.003 · Cited by 117
Bioactive Compounds and their Antioxidant Capacity in Selected Primitive and Modern Wheat Species
Abdel‐Aal, E. M., & Rabalski, I. (2008) · The Open Agriculture Journal · doi:10.2174/1874331500802010007 · Cited by 105
Clinical Practice Guidelines for Healthy Eating for the Prevention and Treatment of Metabolic and Endocrine Diseases in Adults: Cosponsored by the American Association of Clinical Endocrinologists/The American College of Endocrinology and the Obesity Society Executive Summary
González-Campoy, J. M., Jeor, S. T. S., CASTORINO, K. N., Ebrahim, A., Hurley, D., Jovanovič, L., Mechanick, J. I., Petak, S. M., Yu, Y., Harris, K. A., et al. (2013) · Endocrine Practice · doi:10.4158/ep13155.esgl · Cited by 102
Self-citation
Clinical Practice Guidelines for Healthy Eating for the Prevention and Treatment of Metabolic and Endocrine Diseases in Adults: Cosponsored by the American Association of Clinical Endocrinologists/The American College of Endocrinology and the Obesity Society
González-Campoy, J. M., CASTORINO, K. N., Ebrahim, A., Hurley, D., Jovanovič, L., Mechanick, J. I., Petak, S. M., Yu, Y., Jeor, S. T. S., Harris, K. A., et al. (2013) · Endocrine Practice · doi:10.4158/ep13155.gl · Cited by 107
Self-citation
Cereal grains for nutrition and health benefits: Overview of results from in vitro, animal and human studies in the HEALTHGRAIN project
Björck, I., Östman, E. M., Kristensen, M., Anson, N. M., Price, R. K., Haenen, G. R. M. M., Havenaar, R., Knudsen, K. E. B., Frid, A. H., Mykkänen, H. M., et al. (2011) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2011.11.005 · Cited by 101
TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice
da Costa, R. M., Neves, K. B., Mestriner, F., Louzada‐Júnior, P., Bruder-Nascimento, T. B., & Tostes, R. C. (2016) · Cardiovascular Diabetology · doi:10.1186/s12933-016-0443-0 · Cited by 99
Rye Whole Grain and Bran Intake Compared with Refined Wheat Decreases Urinary C-Peptide, Plasma Insulin, and Prostate Specific Antigen in Men with Prostate Cancer1–3
Landberg, R., Andersson, S., Zhang, J., Johansson, J., Stenman, U., Adlercreutz, H., Kamal‐Eldin, A., Åman, P., & Hallmans, G. (2010) · Journal of Nutrition · doi:10.3945/jn.110.127688 · Cited by 96
Whole-grain products and whole-grain types are associated with lower all-cause and cause-specific mortality in the Scandinavian HELGA cohort
Johnsen, N. F., Frederiksen, K., Christensen, J., Skeie, G., Lund, E., Landberg, R., Johansson, I., Nilsson, L. M., Halkjær, J., Olsen, A., et al. (2015) · British Journal of Nutrition · doi:10.1017/s0007114515001701 · Cited by 95
Effects of Whole-Grain Rice and Wheat on Composition of Gut Microbiota and Short-Chain Fatty Acids in Rats
Han, F., Wang, Y., Han, Y., Zhao, J., Han, F., Song, G., Jiang, P., & Miao, H. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b01891 · Cited by 94
Dietary Fibre as a Unifying Remedy for the Whole Spectrum of Obesity-Associated Cardiovascular Risk
Bozzetto, L., Costabile, G., Pepa, G. D., Ciciola, P., Vetrani, C., Vitale, M., Rivellese, A. A., & Annuzzi, G. (2018) · Nutrients · doi:10.3390/nu10070943 · Cited by 98
In defence of phytochemical-rich dietary patterns
McKeown, N. M., & Jacobs, D. R. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510000656 · Cited by 89
Substituting whole grains for refined grains in a 6-wk randomized trial favorably affects energy-balance metrics in healthy men and postmenopausal women
Karl, J. P., Meydani, M., Barnett, J. B., Vanegas, S. M., Goldin, B., Kane, A., Rasmussen, H., Saltzman, E., Vangay, P., Knights, D., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.139683 · Cited by 89
Wholegrain Intake and Risk of Type 2 Diabetes: Evidence from Epidemiological and Intervention Studies
Pepa, G. D., Vetrani, C., Vitale, M., & Riccardi, G. (2018) · Nutrients · doi:10.3390/nu10091288 · Cited by 91
Digestion and metabolic fates of starch, and its relation to major nutrition‐related health problems: A review
Svihus, B., & Hervik, A. K. (2015) · Starch - Stärke · doi:10.1002/star.201500295 · Cited by 91
Recommendations for reporting whole-grain intake in observational and intervention studies
Ross, A. B., Kristensen, M., Seal, C. J., Jacques, P. F., & McKeown, N. M. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.098046 · Cited by 85
Whole grain cereals for the primary or secondary prevention of cardiovascular disease
Kelly, S. A., Hartley, L., Loveman, E., Colquitt, J. L., Jones, H. M., Al-Khudairy, L., Clar, C., Germanò, R., Lunn, H. R., Frost, G. S., et al. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005051.pub3 · Cited by 84
Perspective: Whole and Refined Grains and Health—Evidence Supporting “Make Half Your Grains Whole”
Jones, J. M., Guzmán, C., & Braun, H. J. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz114 · Cited by 90
A whole-grain diet reduces peripheral insulin resistance and improves glucose kinetics in obese adults: A randomized-controlled trial
Malin, S. K., Kullman, E. L., Scelsi, A. R., Haus, J. M., Filion, J., Pagadala, M. R., Godin, J.-P., Kochhar, S., Ross, A. B., & Kirwan, J. P. (2018) · Metabolism · doi:10.1016/j.metabol.2017.12.011 · Cited by 82
Effect of macronutrient composition on short-term food intake and weight loss
Bellissimo, N., & Akhavan, T. (2015) · Advances in Nutrition · doi:10.3945/an.114.006957 · Cited by 56
Effects of whole and refined grains in a weight-loss diet on markers of metabolic syndrome in individuals with increased waist circumference: a randomized controlled-feeding trial
Jackson, K. H., West, S. G., Heuvel, J. P. V., Jonnalagadda, S. S., Ross, A. B., Hill, A. M., Grieger, J. A., Lemieux, S. K., & Kris‐Etherton, P. M. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.078048 · Cited by 82
Self-citation
Effect of dietary fiber on circulating C-reactive protein in overweight and obese adults: a meta-analysis of randomized controlled trials
Jiao, J., Xu, J.-Y., Zhang, W., Han, S., & Qin, L.-Q. (2015) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2014.959898 · Cited by 93
Recent Advances in Preventive Cardiology and Lifestyle Medicine
Franklin, B. A., & Cushman, M. (2011) · Circulation · doi:10.1161/circulationaha.110.981613 · Cited by 82
A High Legume Low Glycemic Index Diet Improves Serum Lipid Profiles in Men
Zhang, Z., Lanza, E., Kris‐Etherton, P. M., Colburn, N. H., Bagshaw, D., Rovine, M. J., Ulbrecht, J. S., Bobe, G., Chapkin, R. S., & Hartman, T. J. (2010) · Lipids · doi:10.1007/s11745-010-3463-7 · Cited by 87
Self-citation
A new dietary strategy for long-term treatment of the metabolic syndrome is compared with the American Heart Association (AHA) guidelines: the MEtabolic Syndrome REduction in NAvarra (RESMENA) project
de la Iglesia, R., Lopez‐Legarrea, P., Abete, I., Bondia‐Pons, I., Navas‐Carretero, S., Forga, L., Martínez, J. A., & Zulet, M. Á. (2013) · British Journal Of Nutrition · doi:10.1017/s0007114513002778 · Cited by 78
The Role of Whole Grains in Body Weight Regulation
Karl, J. P., & Saltzman, E. J. (2012) · Advances in Nutrition · doi:10.3945/an.112.002782 · Cited by 76
Dietary tartary buckwheat intake attenuates insulin resistance and improves lipid profiles in patients with type 2 diabetes: a randomized controlled trial
Qiu, J., Liu, Y., Yue, Y., Qin, Y., & Li, Z. (2016) · Nutrition Research · doi:10.1016/j.nutres.2016.11.007 · Cited by 72
Whole-grain consumption and its effects on hepatic steatosis and liver enzymes in patients with non-alcoholic fatty liver disease: a randomised controlled clinical trial
Dorosti, M., Heidarloo, A. J., Bakhshimoghaddam, F., & Alizadeh, M. (2019) · British Journal Of Nutrition · doi:10.1017/s0007114519002769 · Cited by 73
Higher baseline irisin concentrations are associated with greater reductions in glycemia and insulinemia after weight loss in obese subjects
Lopez-Legarrea, P., de la Iglesia, R., Crujeiras, A. B., Pardo, M., Casanueva, F. F., Zulet, M. A., & Martinez, J. A. (2014) · Nutrition & Diabetes · doi:10.1038/nutd.2014.7 · Cited by 60
The Relationship between Whole Grain Intake and Body Weight: Results of Meta-Analyses of Observational Studies and Randomized Controlled Trials
Maki, K. C., Palacios, O. M., Koecher, K. J., Sawicki, C. M., Livingston, K. A., Bell, M., Cortes, H. N., & McKeown, N. M. (2019) · Nutrients · doi:10.3390/nu11061245 · Cited by 77
Can bioactive foods affect obesity?
Astrup, A. V., Kristensen, M., Gregersen, N. T., Belza, A., Lorenzen, J. K., Due, A., & Larsen, T. M. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05272.x · Cited by 72
Physicochemical and functional properties of yeast fermented brown rice flour
Ilowefah, M. A., Bakar, J., Ghazali, H. M., Mediani, A., & Muhammad, K. (2014) · Journal of Food Science and Technology · doi:10.1007/s13197-014-1661-7 · Cited by 75
Whole Grains: Definition, Dietary Recommendations, and Health Benefits
Slavin, J. L., Tucker, M., Harriman, C., & Jonnalagadda, S. S. (2013) · Cereal Foods World · doi:10.1094/cfw-58-4-0191 · Cited by 69
Effects of rye and whole wheat versus refined cereal foods on metabolic risk factors: A randomised controlled two-centre intervention study
Giacco, R., Lappi, J., Costabile, G., Kolehmainen, M., Schwab, U., Landberg, R., Uusitupa, M. I. J., Poutanen, K. S., Pacini, G., Rivellese, A. A., et al. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2013.01.016 · Cited by 69
The reduction of the metabolyc syndrome in Navarra-Spain (RESMENA-S) study: a multidisciplinary strategy based on chrononutrition and nutritional education, together with dietetic and psychological control.
Zulet, M. Á., Bondia‐Pons, I., Abete, I., de la Iglesia, R., Lopez‐Legarrea, P., Forga, L., Navas‐Carretero, S., & Martínez, J. A. (2011) · PubMed · Cited by 68
Dietary Magnesium Intake and Metabolic Syndrome in the Adult Population: Dose-Response Meta-Analysis and Meta-Regression
Ju, S.-Y., Choi, W.-S., Ock, S.-M., Kim, C.-M., & Kim, D. (2014) · Nutrients · doi:10.3390/nu6126005 · Cited by 69
Whole Grains and Health: from Theory to Practice—Highlights of the Grains for Health Foundation's Whole Grains Summit 2012
McKeown, N. M., Jacques, P. F., Seal, C. J., de Vries, J., Jonnalagadda, S. S., Clemens, R., Webb, D., Murphy, L. A., van Klinken, J., Topping, D. L., et al. (2013) · Journal of Nutrition · doi:10.3945/jn.112.172536 · Cited by 67
Whole-grain intake favorably affects markers of systemic inflammation in obese children: A randomized controlled crossover clinical trial
Hajihashemi, P., Azadbakht, L., Hashemipor, M., Kelishadi, R., & Esmaillzadeh, A. (2014) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201300582 · Cited by 66
Evaluation of the evidence between consumption of refined grains and health outcomes
Williams, P. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00452.x · Cited by 66
Effect of whole grains on markers of subclinical inflammation
Lefevre, M., & Jonnalagadda, S. S. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2012.00487.x · Cited by 64
Comparison of High Protein and High Fiber Weight-Loss Diets in Women with Risk Factors for the Metabolic Syndrome: A Randomized Trial
Te Morenga, L. A., Levers, M. T., Williams, S. M., Brown, R. C., & Mann, J. (2011) · Nutrition Journal · doi:10.1186/1475-2891-10-40 · Cited by 64
Plasma irisin depletion under energy restriction is associated with improvements in lipid profile in metabolic syndrome patients
de la Iglesia, R., Lopez‐Legarrea, P., Crujeiras, A. B., Pardo, M., Casanueva, F. F., Zulet, M. Á., & Martínez, J. A. (2013) · Clinical Endocrinology · doi:10.1111/cen.12383 · Cited by 66
Soy fiber improves weight loss and lipid profile in overweight and obese adults: A randomized controlled trial
Hu, X., Gao, J., Zhang, Q., Fu, Y., Li, K., Zhu, S., & Li, D. (2013) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201300159 · Cited by 64
Whole Grains Are Associated with Serum Concentrations of High Sensitivity C-Reactive Protein among Premenopausal Women ,
Gaskins, A. J., Mumford, S. L., Rovner, A. J., Zhang, C., Chen, L., Wactawski‐Wende, J., Perkins, N. J., & Schisterman, E. F. (2010) · Journal of Nutrition · doi:10.3945/jn.110.124164 · Cited by 64
Increasing Whole Grain Intake as Part of Prevention and Treatment of Nonalcoholic Fatty Liver Disease
Ross, A. B., Godin, J., Minehira, K., & Kirwan, J. P. (2013) · International Journal of Endocrinology · doi:10.1155/2013/585876 · Cited by 64
Effects of bioactive constituents in functional cocoa products on cardiovascular health in humans
Sarriá, B., Martínez-López, S., Sierra-Cinos, J. L., García‐Diz, L., Goya, L., Mateos, R., & Bravo, L. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2014.11.004 · Cited by 63
Profiling the Oxylipin and Endocannabinoid Metabolome by UPLC-ESI-MS/MS in Human Plasma to Monitor Postprandial Inflammation
Gouveia-Figueira, S. C., Späth, J., Zivkovic, A. M., & Nording, M. L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132042 · Cited by 63
In vitro fermentation of potential prebiotic flours from natural sources: Impact on the human colonic microbiota and metabolome
Maccaferri, S., Klinder, A., Cacciatore, S., Chitarrari, R., Honda, H., Luchinat, C., Bertini, I., Carnevali, P., Gibson, G. R., Brigidi, P., et al. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200046 · Cited by 62
Dietary fibre and weight loss: Where are we now?
Brownlee, I. A., Chater, P. I., Pearson, J. P., & Wilcox, M. D. (2016) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2016.08.029 · Cited by 61
Best (but oft-forgotten) practices: sensitivity analyses in randomized controlled trials
de Souza, R. J., Eisen, R. B., Perera, S., Bantoto, B., Bawor, M., Dennis, B. B., Samaan, Z., & Thabane, L. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.121848 · Cited by 63
Whole- and Refined-Grain Consumption and Longitudinal Changes in Cardiometabolic Risk Factors in the Framingham Offspring Cohort
Sawicki, C. M., Jacques, P. F., Lichtenstein, A. H., Rogers, G. T., Ma, J., Saltzman, E. J., & McKeown, N. M. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab177 · Cited by 55
Fibras na dieta: tendências atuais e benefícios à saúde na síndrome metabólica e no diabetes melito tipo 2
de Mello, V. D., & Laaksonen, D. E. (2009) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302009000500004 · Cited by 56
Whole-Grain Consumption Does Not Affect Obesity Measures: An Updated Systematic Review and Meta-analysis of Randomized Clinical Trials
Sadeghi, O., Sadeghian, M., Rahmani, S., Maleki, V., Larijani, B. A., & Esmaillzadeh, A. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz076 · Cited by 53
Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis
Wang, W., Li, J., Chen, X., Yu, M., Pan, Q., & Guo, L. (2020) · BMC Cardiovascular Disorders · doi:10.1186/s12872-020-01337-z · Cited by 53
Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic
Wahls, T. L., Chenard, C. A., & Snetselaar, L. (2019) · Nutrients · doi:10.3390/nu11020352 · Cited by 56
Whole Grain Consumption and Inflammatory Markers: A Systematic Literature Review of Randomized Control Trials
Milesi, G., Rangan, A., & Grafenauer, S. (2022) · Nutrients · doi:10.3390/nu14020374 · Cited by 54
Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
do Nascimento, O. V., Boleti, A. P. D. A., Yuyama, L. K. O., & Lima, É. S. (2013) · Anais da Academia Brasileira de Ciências · doi:10.1590/s0001-37652013005000001 · Cited by 52
Glucose- and Lipid-Related Biomarkers Are Affected in Healthy Obese or Hyperglycemic Adults Consuming a Whole-Grain Pasta Enriched in Prebiotics and Probiotics: A 12-Week Randomized Controlled Trial
Angelino, D., Martina, A., Rosi, A., Veronesi, L., Antonini, M., Mennella, I., Vitaglione, P., Grioni, S., Brighenti, F., Zavaroni, I., et al. (2019) · Journal of Nutrition · doi:10.1093/jn/nxz071 · Cited by 51
Effects of Whole-Grain Consumption on Selected Biomarkers of Systematic Inflammation: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Hajihashemi, P., & Haghighatdoost, F. (2018) · Journal of the American College of Nutrition · doi:10.1080/07315724.2018.1490935 · Cited by 50

Authors: Katcher, H. I., Legro, R. S., Kunselman, A. R., Gillies, P. J., Demers, L. M., Bagshaw, D. M., & Kris-Etherton, P. M.
Affiliations: Pennsylvania State University (US)
DuPont (United States) (US)
ORCID: Legro, Richard S
Kunselman, Allen R
Venue: The American Journal of Clinical Nutrition
Publisher: Elsevier BV
Published: 2008-01
Volume: 87
Issue: 1
Pages: 79-90
ISSN: 0002-9165 (ISSN-L)
DOI: 10.1093/ajcn/87.1.79
OpenAlex: W2153232403
Cited by: 317
References: 51
Citations by year: 2026: 2 · 2025: 3 · 2024: 17 · 2023: 4 · 2022: 8 · 2021: 17 · 2020: 9 · 2019: 18 · 2018: 16 · 2017: 20 · 2016: 19 · 2015: 20 · 2014: 36 · 2013: 34 · 2012: 27
FWCI: 20.35
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5539 d)
Locations: American Journal of Clinical Nutrition (publishedVersion)
PubMed (publishedVersion)
Funders: National Center for Research Resources (M01 RR10732, C06RR016499, M01RR010732)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (K24 HD01476, K24HD001476)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: whole grains, hypocaloric diet, metabolic syndrome, cardiovascular risk factors, weight loss, abdominal fat, C-reactive protein, cholesterol, dietary fiber, dietary magnesium, refined grains, obesity
MeSH terms: Adult, Aged, Body Composition, C-Reactive Protein, Cardiovascular Diseases, Edible Grain, Cholesterol, Diet, Reducing, Dietary Fiber, Female, Humans, Magnesium, Male, Middle Aged, Obesity, Risk Factors, Weight Loss, Body Mass Index, Treatment Outcome, Metabolic Syndrome, Abdominal Fat

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The effects of a whole grain–enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks