Brain activation and sexual arousal in healthy, heterosexual males
Abstract
Despite the brain's central role in sexual function, little is known about relationships between brain activation and sexual response. In this study, we employed functional MRI (fMRI) to examine relationships between brain activation and sexual arousal in a group of young, healthy, heterosexual males. Each subject was exposed to two sequences of video material consisting of explicitly erotic (E), relaxing (R) and sports (S) segments in an unpredictable order. Data on penile turgidity was collected using a custom-built pneumatic pressure cuff. Both traditional block analyses using contrasts between sexually arousing and non-arousing video clips and a regression using penile turgidity as the covariate of interest were performed. In both types of analyses, contrast images were computed for each subject and these images were subsequently used in a random effects analysis. Strong activations specifically associated with penile turgidity were observed in the right subinsular region including the claustrum, left caudate and putamen, right middle occipital/ middle temporal gyri, bilateral cingulate gyrus and right sensorimotor and pre-motor regions. Smaller, but significant activation was observed in the right hypothalamus. Few significant activations were found in the block analyses. Implications of the findings are discussed. Our study demonstrates the feasibility of examining brain activation/sexual response relationships in an fMRI environment and reveals a number of brain structures whose activation is time-locked to sexual arousal.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Similar activation patterns have been seen in response to pictures of romantic partners, beautiful faces, and sexual stimuli, suggesting a link between brain reward circuits and attachment.
“Similar activation patterns have been seen in response to pictures of romantic partners (22), beautiful faces (25) and sexual stimuli (26), suggesting a link between brain reward circuits and attachment.”
From What’s in a smile? Maternal brain responses to infant facial cues (2008) · cites this paper as [26]
In humans, sexual arousal has been associated with increased neural activity within a number of regions within the motivational pathway including in the hypothalamus, striatum, amygdala insula, frontal cortex and cingulate.
“In humans, sexual arousal has been associated with increased neural activity within a number of regions within the motivational pathway including in the hypothalamus, striatum, amygdala insula, frontal cortex and cingulate (Arnow et al., 2002, Hamann et al., 2004, Karama et al., 2002, Park et al., 2001, Rauch et al., 1999, Redoute et al., 2000, Stoleru et al., 1999).”
From Oxytocin, motivation and the role of dopamine (2014) · cites this paper as Arnow et al., 2002
Cites
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798 · see citing works
Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688 · see citing works
The Physiology of Reproduction
Legendre, M., & Jalabert, B. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,879 · see citing works
Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997) · Urology · doi:10.1016/s0090-4295(97)00238-0 · Cited by 5,849 · see citing works
Spatial registration and normalization of images
Friston, K. J., Ashburner, J., Frith, C., Poline, J.-B., Heather, J. D., & Frackowiak, R. S. J. (1995) · Human Brain Mapping · doi:10.1002/hbm.460030303 · Cited by 3,744 · see citing works
Contributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377 · see citing works
Lr, D., & Derogatis, L. R. (1983) · Medical Entomology and Zoology · Cited by 2,027 · see citing works
Assessing the significance of focal activations using their spatial extent
Friston, K. J., Worsley, K. J., Frackowiak, R. S. J., Mazziotta, J. C., & Evans, A. C. (1994) · Human Brain Mapping · doi:10.1002/hbm.460010306 · Cited by 1,907 · see citing works
Functional mapping of the human visual cortex by magnetic resonance imaging
Belliveau, J. W., Kennedy, D. N., McKinstry, R. C., Buchbinder, B. R., Weisskoff, R. M., Cohen, M. S., Vevea, J. M., Brady, T. J., & Rosen, B. R. (1991) · Science · doi:10.1126/science.1948051 · Cited by 1,883 · see citing works
Circuitry and functional aspects of the insular lobe in primates including humans
AUGUSTINE, J. (1996) · Brain Research Reviews · doi:10.1016/s0165-0173(96)00011-2 · Cited by 1,776 · see citing works
Structured Clinical Interview for DSM-III-R Personality Disorders
First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (2012) · PsycTESTS Dataset · doi:10.1037/t07827-000 · Cited by 1,403 · see citing works
Lue, T. F. (2000) · New England Journal of Medicine · doi:10.1056/nejm200006153422407 · Cited by 1,261 · see citing works
Self-citationRisperidone in the treatment of schizophrenia
Marder, S. R., & Meibach, R. C. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.6.825 · Cited by 1,194 · see citing works
The physiology of male sexual behavior
Meisel, R. (1994) · Medical Entomology and Zoology · Cited by 988 · see citing works
Functional Magnetic Resonance Imaging of Motor Cortex: Hemispheric Asymmetry and Handedness
Kim, S., Ashe, J., Hendrich, K. S., Ellermann, J., Merkle, H., Uǧurbil, K., & Georgopoulos, A. P. (1993) · Science · doi:10.1126/science.8342027 · Cited by 984 · see citing works
Engel, S. A., Rumelhart, D. E., Wandell, B. A., Lee, A. T.-J., Glover, G. H., Chichilnisky, E. J., & Shadlen, M. N. (1994) · Nature · doi:10.1038/369525a0 · Cited by 977 · see citing works
Self-citationGeneralisability, Random Effects & Population Inference
Holmes, A. P., & Friston, K. J. (1998) · NeuroImage · doi:10.1016/s1053-8119(18)31587-8 · Cited by 906 · see citing works
Rauch, S. L. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010062008 · Cited by 880 · cited 1× · see citing works
“Abnormalities in anterior cingulate function have been reported in patients with obsessive±compulsive disorder (Rauch et al., 1994), autism (Ohnishi et al., 2000), and autism spectrum disorders (Haznedar et al., 2000), all of which are characterized by repetitive behaviour and dif®culties shifting…”
BackgroundPlasma oxytocin increases in the human sexual response
CARMICHAEL, M. S., HUMBERT, R., DIXEN, J., PALMISANO, G., GREENLEAF, W., & DAVIDSON, J. M. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-1-27 · Cited by 554 · cited 1× · see citing works
“In studies of humans, pituitary secretion of oxytocin from the paraventricular nucleus has been shown to increase during sexual arousal in males and females (Carmichael et al., 1987, 1994).”
BackgroundBrain processing of visual sexual stimuli in human males
Redout�, J., Stol�ru, S., Gr�goire, M.-C., Costes, N., Cinotti, L., Lavenne, F., Bars, D. L., Forest, M. G., & Pujol, J. F. (2000) · Human Brain Mapping · doi:10.1002/1097-0193(200011)11:3 · Cited by 517 · see citing works
Self‐navigated spiral fMRI: Interleaved versus single‐shot
Glover, G. H., & Lai, S. (1998) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910390305 · Cited by 476 · see citing works
Self-citationAbnormal regional cerebral blood flow in childhood autism
Ohnishi, T. (2000) · Brain · doi:10.1093/brain/123.9.1838 · Cited by 439 · see citing works
Haznedar, M. M., Buchsbaum, M. S., Wei, T.-C., Hof, P. R., Cartwright, C., Bienstock, C. A., & Hollander, E. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.12.1994 · Cited by 420 · see citing works
Neuroanatomical Correlates of Visually Evoked Sexual Arousal in Human Males
Stoléru, S., Grégoire, M., Gérard, D., Decety, J., Lafarge, E., Cinotti, L., Lavenne, F., Bars, D. L., Vernet-Maury, E., Rada, H., et al. (1999) · Archives of Sexual Behavior · doi:10.1023/a:1018733420467 · Cited by 418 · see citing works
Jack, C. R., Thompson, R. M., Butts, R. K., Sharbrough, F. W., Kelly, P. J., Hanson, D. P., Riederer, S. J., Ehman, R. L., Hangiandreou, N. J., & Cascino, G. D. (1994) · Radiology · doi:10.1148/radiology.190.1.8259434 · Cited by 369 · see citing works
Brain responses associated with consciousness of breathlessness (air hunger)
Mario Liotti, A., Brannan, S., Egan, G. F., Shade, R. E., Madden, L., Abplanalp, B., Robillard, R., Lancaster, J. L., Zamarripa, F., Fox, P. T., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.2035 · Cited by 304 · see citing works
Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity
Carmichael, M. S., Warburton, V. L., Dixen, J., & Davidson, J. M. (1994) · Archives of Sexual Behavior · doi:10.1007/bf01541618 · Cited by 276 · see citing works
Burton, H., Videen, T. O., & Raichle, M. E. (1993) · Somatosensory & Motor Research · doi:10.3109/08990229309028839 · Cited by 267 · see citing works
The insular lobe in primates including humans
Augustine, J. R. (1985) · Neurological Research · doi:10.1080/01616412.1985.11739692 · Cited by 224 · see citing works
Hadjikhani, N. K., & Roland, P. E. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-03-01072.1998 · Cited by 224 · see citing works
Sexual dysfunction in male schizophrenic patients.
Aizenberg, D., Zemishlany, Z., Dorfman-Etrog, P., & Weizman, A. (1995) · PubMed · Cited by 213 · see citing works
Dopaminergic control of male sex behavior in rats: Effects of an intracerebrally-infused agonist
Hull, E. M., Bitran, D., Pehek, E. A., Warner, R. K., Band, L. C., & Holmes, G. M. (1986) · Brain Research · doi:10.1016/0006-8993(86)91106-6 · Cited by 211 · see citing works
An inventory for the measurement of female sexual arousability: The SAI
Hoon, E. F., Hoon, P. W., & Wincze, J. P. (1976) · Archives of Sexual Behavior · doi:10.1007/bf01542081 · Cited by 198 · see citing works
Brannan, S., Mario Liotti, A., Egan, G. F., Shade, R. E., Madden, L., Robillard, R., Abplanalp, B., Stofer, K. A., Denton, D. A., & Fox, P. T. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.2029 · Cited by 188 · see citing works
Cross-modal performance: behavioural processes, phylogenetic considerations and neural mechanisms
Ettlinger, G., & Wilson, W. A. (1990) · Behavioural Brain Research · doi:10.1016/0166-4328(90)90075-p · Cited by 172 · see citing works
Park, K., Seo, J., Kang, H., Ryu, S., Kim, H., & Jeong, G. (2001) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900649 · Cited by 162 · see citing works
Heterosexual behavior assessment—I. Males
Bentler, P. M. (1968) · Behaviour Research and Therapy · doi:10.1016/0005-7967(68)90037-5 · Cited by 158 · see citing works
fMRI Study of Face Perception and Memory Using Random Stimulus Sequences
Clark, V. P., Maisog, J. M., & Haxby, J. V. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.6.3257 · Cited by 144 · see citing works
Gustatory neural coding in the monkey cortex: stimulus intensity
Scott, T. R., Plata‐Saláman, C. R., Smith‐Swintosky, V. L., & Giza, B. K. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.65.1.76 · Cited by 133 · see citing works
Sexual Behavior During L-dopa Treatment for Parkinsonism
Bowers, M. B., WOERT, M. V., & DAVIS, L. (1971) · American Journal of Psychiatry · doi:10.1176/ajp.127.12.1691 · Cited by 127 · see citing works
Alimentary responses to forebrain stimulation in monkeys
Robinson, B. W., & Mishkin, M. M. (1968) · Experimental Brain Research · doi:10.1007/bf00235700 · Cited by 118 · see citing works
Neuroimaging evidence implicating cerebellum in the experience of hypercapnia and hunger for air
Parsons, L. M., Egan, G. F., Mario Liotti, A., Brannan, S., Denton, D. A., Shade, R. E., Robillard, R., Madden, L., Abplanalp, B., & Fox, P. T. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.2041 · Cited by 115 · see citing works
Direct comparison of the neural substrates of recognition memory for words and faces
Kim, J., Andreasen, N. C., OʼLeary, D. S., Wiser, A. K., Ponto, L. L. B., Watkins, G. L., & Hichwa, R. D. (1999) · Brain · doi:10.1093/brain/122.6.1069 · Cited by 115 · see citing works
Chen, K., Chan, S. H. H., Chang, L. S.-S., & Chan, J. Y. H. (1997) · The Journal of Urology · doi:10.1097/00005392-199707000-00078 · Cited by 109 · see citing works
Gustatory neural coding in the monkey cortex: stimulus quality
Smith‐Swintosky, V. L., Plata‐Saláman, C. R., & Scott, T. R. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.66.4.1156 · Cited by 88 · see citing works
Mental Effects of High-Dosage Levodopa
O’Brien, C. P. (1971) · Archives of General Psychiatry · doi:10.1001/archpsyc.1971.01750070063008 · Cited by 85 · see citing works
Aziz, Q., Furlong, P. L., Barlow, J. D., Hobson, A. R., ALANI, S. M., Bancewicz, J., Ribbands, M. S., Harding, G. F. A., & Thompson, D. G. (1995) · Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section · doi:10.1016/0168-5597(94)00297-r · Cited by 82 · see citing works
Hörster, W., Rivers, A., Schuster, B., et al. (1989) · Behavioural Brain Research · doi:10.1016/s0166-4328(89)80052-x · Cited by 77 · see citing works
Time course of the subjective emotional response to aversive pictures: relevance to fMRI studies
Garrett, A. S., & Maddock, R. J. (2001) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(01)00110-x · Cited by 76 · see citing works
Apomorphine: Clinical studies on erectile impotence and yawning
Lal, S., Tesfaye, Y., Thavundayil, J., et al. (1989) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(89)90122-x · Cited by 70 · see citing works
THE ACTIVATING EFFECT OF L-DOPA TREATMENT ON SEXUAL FUNCTIONS AND ITS EXPERIMENTAL BACKGROUND
Hyyppä, M. T., Rinne, U. K., & Sonninen, V. H. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1970.tb02198.x · Cited by 62 · see citing works
D2 receptors in the paraventricular nucleus regulate genital responses and copulation in male rats
Eaton, R. C., Markowski, V. P., Lumley, L. A., Thompson, J. T., Moses, J., & Hull, E. M. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90418-2 · Cited by 61 · see citing works
McKenna, K. E. (1999) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900484 · Cited by 58 · see citing works
FUNCTIONAL MR IMAGING: Capabilities and Limitations
Moseley, M. E., & Glover, G. H. (1995) · Neuroimaging Clinics of North America · doi:10.1016/s1052-5149(25)00289-8 · Cited by 52 · see citing works
Self-citationMale sexual arousal elicited by film and fantasy matched in content
Koukounas, E., & Over, R. (1997) · Australian Journal of Psychology · doi:10.1080/00049539708259843 · Cited by 27 · see citing works
Crowe, S. F. (1999) · Brain Injury · doi:10.1080/026990599121539 · Cited by 21 · see citing works
Somatosensory evoked potentials following lesions of the claustrum.
Moryś, J., Słoniewski, P., & Narkiewicz, O. (1989) · PubMed · Cited by 11 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The neural correlates of maternal and romantic love
Bartels, A., & Zeki, S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.11.003 · Cited by 1,448 · see citing works
Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love
Aron, A., Fisher, H., Mashek, D. J., Strong, G., Li, H., & Brown, L. L. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00838.2004 · Cited by 963 · see citing works
Processing of Social and Monetary Rewards in the Human Striatum
Izuma, K., Saito, D. N., & Sadato, N. (2008) · Neuron · doi:10.1016/j.neuron.2008.03.020 · Cited by 855 · see citing works
The hidden island of addiction: the insula
Naqvi, N. H., & Bechara, A. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2008.09.009 · Cited by 833 · see citing works
Sescousse, G., Caldú, X., Segura, B., & Dreher, J.-C. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.002 · Cited by 782 · see citing works
Gr�sser, S. M., Wrase, J., Klein, S., Hermann, D., Smolka, M. N., Ruf, M., Weber-Fahr, W., Flor, H., Mann, K., Braus, D. F., et al. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1828-4 · Cited by 598 · see citing works
The insula and drug addiction: an interoceptive view of pleasure, urges, and decision-making
Naqvi, N. H., & Bechara, A. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0268-7 · Cited by 598 · see citing works
The neural substrates of reward processing in humans: the modern role of FMRI
McClure, S. M., York, M. K., & Montague, P. R. (2004) · The Neuroscientist · doi:10.1177/1073858404263526 · Cited by 480 · see citing works
Voon, V., Mole, T. B., Banca, P., Porter, L., Morris, L., Mitchell, S., Lapa, T. R., Karr, J., Harrison, N. A., Potenza, M. N., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102419 · Cited by 462 · see citing works
What’s in a smile? Maternal brain responses to infant facial cues
Strathearn, L., Li, J., Fonagy, P., & Montague, P. R. (2008) · Pediatrics · doi:10.1542/peds.2007-1566 · Cited by 460 · see citing works
Romantic love: a mammalian brain system for mate choice
Fisher, H. E., Aron, A., & Brown, L. L. (2006) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2006.1938 · Cited by 411 · see citing works
Romantic love: an fMRI study of a neural mechanism for mate choice.
Fisher, H., Aron, A., & Brown, L. L. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20772 · Cited by 396 · see citing works
Oxytocin, motivation and the role of dopamine
Love, T. M. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.06.011 · Cited by 369 · see citing works
Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI
Ferretti, A., Caulo, M., Del Gratta, C., Di Matteo, R., Merla, A., Montorsi, F., Pizzella, V., Pompa, P., Rigatti, P., Rossini, P. M., et al. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.025 · Cited by 288 · see citing works
Neuroscience of Internet Pornography Addiction: A Review and Update
Love, T., Laier, C., Brand, M., Hatch, L., & Hajela, R. (2015) · Behavioral Sciences · doi:10.3390/bs5030388 · Cited by 262 · see citing works
Brand, M., Snagowski, J., Laier, C., & Maderwald, S. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.01.033 · Cited by 198 · see citing works
Politis, M., Loane, C., Wu, K., O’Sullivan, S. S., Woodhead, Z., Kiferle, L., Lawrence, A. D., Lees, A. J., & Piccini, P. (2013) · Brain · doi:10.1093/brain/aws326 · Cited by 191 · see citing works
Is internet pornography causing sexual dysfunctions? A review with clinical reports
Park, B., Wilson, G., Berger, J., Christman, M., Reina, B., Bishop, F., Klam, W., & Doan, A. (2016) · Behavioral Sciences · doi:10.3390/bs6030017 · Cited by 187 · see citing works
Andrews, M. M., Meda, S. A., Thomas, A. D., Potenza, M. N., Krystal, J. H., Worhunsky, P., Stevens, M. C., O'Malley, S., Book, G. A., Reynolds, B., et al. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.049 · Cited by 181 · see citing works
Schaefer, H. S., Putnam, K. M., Benca, R. M., & Davidson, R. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.024 · Cited by 158 · see citing works
Physiology of women's sexual function: basic knowledge and new findings.
Salonia, A., Giraldi, A., Chivers, M. L., Georgiadis, J. R., Levin, R., Maravilla, K. R., & McCarthy, M. M. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.01810.x · Cited by 132 · see citing works
Brain processing of visual sexual stimuli in treated and untreated hypogonadal patients
Redouté, J., Stoléru, S., Pugeat, M., Costes, N., Lavenne, F., Le Bars, D., Dechaud, H., Cinotti, L., & Pujol, J.-F. (2005) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2004.12.003 · Cited by 126 · see citing works
Neural Substrates of Sexual Desire in Individuals with Problematic Hypersexual Behavior
Seok, J.-W., & Sohn, J.-H. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00321 · Cited by 118 · see citing works
Metzger, C. D. (2010) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2010.00138 · Cited by 114 · see citing works
Neural correlates of erotic stimulation under different levels of female sexual hormones
Abler, B., Kumpfmüller, D., Grön, G., Walter, M., Stingl, J., & Seeringer, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054447 · Cited by 75 · see citing works
Wassersug, R., & Wibowo, E. (2017) · Translational Andrology and Urology · doi:10.21037/tau.2017.04.09 · Cited by 45 · see citing works
Shih, H.-C., Kuo, M.-E., Wu, C., Chao, Y.-P., Huang, H.-W., & Huang, C.-M. (2022) · Brain Sciences · doi:10.3390/brainsci12070830 · Cited by 32 · see citing works
Male brain processing of the body odor of ovulating women compared to that of pregnant women
Habel, U., Regenbogen, C., Kammann, C., Stickel, S., & Chechko, N. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.117733 · Cited by 8 · see citing works
- Authors
- Arnow, B. A., Desmond, J. E., Banner, L. L., Glover, G. H., Solomon, A., Polan, M. L., Lue, T. F., & Atlas, S. W.
- Affiliations
- Stanford Medicine (US)
- Corresponding author
- Arnow, Bruce A.
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-05
- Volume
- 125
- Issue
- 5
- Pages
- 1014-1023
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- OpenAlex
- W2105824840
- Cited by
- 425
- References
- 57
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 11 · 2023: 13 · 2022: 13 · 2021: 4 · 2020: 16 · 2019: 12 · 2018: 20 · 2017: 23 · 2016: 28 · 2015: 24 · 2014: 18 · 2013: 32 · 2012: 23
- FWCI
- 10.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- sexual arousal, brain activation, heterosexual men, claustrum, caudate nucleus, putamen, cingulate gyrus, hypothalamus, sensorimotor cortex, premotor cortex, sexual response
- MeSH terms
- Adolescent, Adult, Arousal, Brain, Brain Mapping, Humans, Magnetic Resonance Imaging, Male, Penile Erection, Photic Stimulation, Regression Analysis, Sexual Behavior, Heterosexuality
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
