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Mechanisms of Vascular Aging: New Perspectives
Open accessAbstract
This review focuses on molecular, cellular, and functional changes that occur in the vasculature during aging; explores the links between mitochondrial oxidative stress, inflammation, and development of vascular disease in the elderly patients; and provides a landscape of molecular mechanisms involved in cellular oxidative stress resistance, which could be targeted for the prevention or amelioration of unsuccessful vascular aging. Practical interventions for prevention of age-associated vascular dysfunction and disease in old age are considered here based on emerging knowledge of the effects of anti-inflammatory treatments, regular exercise, dietary interventions, and caloric restriction mimetics.
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Ungvari, Z., Tarantini, S., Donato, A. J., Galvan, V., & Csiszar, A. (2018) · Circulation Research · doi:10.1161/circresaha.118.311378 · Cited by 919
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Self-citation
Metadata
- Authors
- Ungvari, Z., Kaley, G., de Cabo, R., Sonntag, W. E., & Csiszar, A.
- Venue
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-06-24
- Volume
- 65A
- Issue
- 10
- Pages
- 1028-1041
- ISSN
- 1079-5006 (ISSN-L)
- 1758-535X
- OpenAlex
- W2153273912
- Cited by
- 531
- References
- 27
- FWCI
- 26.37
- Type
- journal article
- Language
- en
- Open access
- bronze
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