Does Participation in Leisure Activities Lead to Reduced Risk of Alzheimer's Disease? A Prospective Study of Swedish Twins

Crowe, M.; Andel, R.; Pedersen, N. L.; Johansson, B.; Gatz, M.

doi:10.1093/geronb/58.5.p249

Cited by 252Dementia and Cognitive Impairment ResearchAging and Gerontology ResearchRecreation, Leisure, Wilderness Management

Does Participation in Leisure Activities Lead to Reduced Risk of Alzheimer's Disease? A Prospective Study of Swedish Twins

Crowe, M., Andel, R., Pedersen, N. L., Johansson, B., Gatz, M.·2003·The Journals of Gerontology Series B: Psychological Sciences and Social Sciences

DOI 10.1093/geronb/58.5.p249

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Abstract

This study examined whether participation in leisure activities during early and middle adulthood was associated with reduced risk of Alzheimer's disease. The sample consisted of 107 same-sex twin pairs discordant for dementia and for whom information on leisure activities was self-reported more than 20 years prior to clinical evaluation. A factor analysis of these activities yielded three activity factors: intellectual-cultural, self-improvement, and domestic activity. Matched-pair analyses compared activities within the discordant twin pairs while controlling for level of education. For the total sample, participation in a greater overall number of leisure activities was associated with lower risk of both Alzheimer's disease and dementia in general. Greater participation in intellectual-cultural activities was associated with lower risk of Alzheimer's disease for women, although not for men.

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Crowe et al. found that greater participation in cognitive activities was associated with reduced risk of Alzheimer's disease 20 years later, although the association in this small cohort was only significant for women.
“Greater participation in cognitive activities was associated with a reduced risk of Alzheimer's disease 20 years later, although the association in this small cohort was only significant for women.”
From Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced? (2008) · cites this paper as Crowe et al., 2003
Level of cognitive activity has long-term predictive validity for the incidence of dementia, including prospective prediction over a 2-decade span in one study.
“level of cognitive activity has long-term predictive validity for the incidence of dementia, including prospective prediction over a 2-decade span in one study (Crowe et al., 2003).”
From Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced? (2008) · cites this paper as Crowe et al., 2003

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Authors: Crowe, M., Andel, R., Pedersen, N. L., Johansson, B., & Gatz, M.
Affiliations: University of Southern California (US)
Australian National University (AU)
Flinders University (AU)
Corresponding author: Crowe, M.
ORCID: Crowe, M.
Andel, R.
Johansson, B.
Gatz, M.
Venue: The Journals of Gerontology Series B: Psychological Sciences and Social Sciences
Publisher: Oxford University Press (OUP)
Published: 2003-09-01
Volume: 58
Issue: 5
Pages: P249-P255
ISSN: 1079-5014 (ISSN-L)
1758-5368
DOI: 10.1093/geronb/58.5.p249
OpenAlex: W2141197239
Cited by: 252
References: 41
Citations by year: 2026: 1 · 2025: 9 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 10 · 2020: 12 · 2019: 12 · 2018: 10 · 2017: 15 · 2016: 15 · 2015: 11 · 2014: 12 · 2013: 15 · 2012: 10
FWCI: 4.69
Type: journal article
Language: en
Open access: closed
Locations: The Journals of Gerontology Series B (publishedVersion)
PubMed (publishedVersion)
Funders: ALS Association
Australian Association of Gerontology
Australian Rotary Health
Flinders University
Australian Research Council
National Health and Medical Research Council (366756)
National Institute on Aging (R01AG004563, AG-10175, R01-AG08724, AG04563, AG 08861, R01AG010175, R01AG008724)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
Social Sciences › Psychology › Social Psychology › Recreation, Leisure, Wilderness Management
Keywords: leisure, Alzheimer's disease, dementia risk, domestic activities, sex differences
MeSH terms: Aged, Alzheimer Disease, Cognition Disorders, Female, Humans, Interpersonal Relations, Leisure Activities, Male, Neuropsychological Tests, Prospective Studies, Surveys and Questionnaires, Registries, Twins, Incidence, Sex Distribution

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Does Participation in Leisure Activities Lead to Reduced Risk of Alzheimer's Disease? A Prospective Study of Swedish Twins

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