Cinnamon Supplementation Does Not Improve Glycemic Control in Postmenopausal Type 2 Diabetes Patients
Open accessAbstract
In vitro and in vivo animal studies have reported strong insulin-like or insulin-potentiating effects after cinnamon administration. Recently, a human intervention study showed that cinnamon supplementation (1 g/d) strongly reduced fasting blood glucose concentration (30%) and improved the blood lipid profile in patients with type 2 diabetes. The objective of this study was to investigate the effects of cinnamon supplementation on insulin sensitivity and/or glucose tolerance and blood lipid profile in patients with type 2 diabetes. Therefore, a total of 25 postmenopausal patients with type 2 diabetes (aged 62.9 +/- 1.5 y, BMI 30.4 +/- 0.9 kg/m2) participated in a 6-wk intervention during which they were supplemented with either cinnamon (Cinnamomum cassia, 1.5 g/d) or a placebo. Before and after 2 and 6 wk of supplementation, arterialized blood samples were obtained and oral glucose tolerance tests were performed. Blood lipid profiles and multiple indices of whole-body insulin sensitivity were determined. There were no time x treatment interactions for whole-body insulin sensitivity or oral glucose tolerance. The blood lipid profile of fasting subjects did not change after cinnamon supplementation. We conclude that cinnamon supplementation (1.5 g/d) does not improve whole-body insulin sensitivity or oral glucose tolerance and does not modulate blood lipid profile in postmenopausal patients with type 2 diabetes. More research on the proposed health benefits of cinnamon supplementation is warranted before health claims should be made.
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Cinnamon extracts have been known for managing blood glucose.
“Cinnamon extracts have been known for managing blood glucose.”
Results from 6 RCTs did not find a difference in blood glucose or insulin levels after cinnamon consumption.
“Results from 6 RCTs did not find a difference in blood glucose or insulin levels after cinnamon consumption [368,377,378,379,380,381,382].”
From Effects of diet, lifestyle, Chrononutrition and alternative dietary interventions on postprandial Glycemia and insulin resistance (2022) · cites this paper as [382]
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Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502 · see citing works
Wild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004) · Diabetes Care · doi:10.2337/diacare.27.5.1047 · Cited by 15,297 · see citing works
Matsuda, M., & DeFronzo, R. A. (1999) · Diabetes Care · doi:10.2337/diacare.22.9.1462 · Cited by 5,621 · see citing works
Cinnamon improves glucose and lipids of people with type 2 diabetes
Khan, A., Safdar, M., Ali Khan, M. M., Khattak, K. N., & Anderson, R. A. (2003) · Diabetes Care · doi:10.2337/diacare.26.12.3215 · Cited by 981 · see citing works
Glycemic index: overview of implications in health and disease,,,
Jenkins, D. J., Kendall, C. W., Augustin, L. S., Franceschi, S., Hamidi, M., Marchie, A., Jenkins, A. L., & Axelsen, M. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.1.266s · Cited by 827 · see citing works
A Model-Based Method for Assessing Insulin Sensitivity From the Oral Glucose Tolerance Test
Mari, A., Pacini, G., Murphy, E., Ludvik, B. H., & Nolan, J. J. (2001) · Diabetes Care · doi:10.2337/diacare.24.3.539 · Cited by 805 · see citing works
Glycemic index, glycemic load, and risk of type 2 diabetes,,
Willett, W., Manson, J., & Liu, S. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.1.274s · Cited by 726 · see citing works
The IRS-signalling system: A network of docking proteins that mediate insulin action
White, M. F. (1998) · Springer eBooks · doi:10.1007/978-1-4615-5647-3_1 · Cited by 673 · see citing works
Anderson, R. A., Broadhurst, C. L., Polansky, M. M., Schmidt, W. F., Khan, A., Flanagan, V. P., Schoene, N. W., & Graves, D. J. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf034916b · Cited by 561 · see citing works
The IRS-signalling system: A network of docking proteins that mediate insulin action
White, M. F. (1998) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006806722619 · Cited by 534 · see citing works
Non-Insulin-Dependent Diabetes Mellitus in Minorities in the United States
Carter, J. S., Pugh, J., & Monterrosa, A. (1996) · Annals of Internal Medicine · doi:10.7326/0003-4819-125-3-199608010-00011 · Cited by 504 · see citing works
Insulin-like Biological Activity of Culinary and Medicinal Plant Aqueous Extracts in Vitro
Broadhurst, C. L., Polansky, M. M., & Anderson, R. A. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9904517 · Cited by 429 · see citing works
A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes
Jarvill-Taylor, K. J., Anderson, R. A., & Graves, D. J. (2001) · Journal of the American College of Nutrition · doi:10.1080/07315724.2001.10719053 · Cited by 324 · see citing works
Qin, B., Nagasaki, M., Ren, M., Bajotto, G., Oshida, Y., & Sato, Y. (2003) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(03)00173-6 · Cited by 298 · see citing works
Folli, F. B., Saad, M. J. A., Backer, J., & Kahn, C. R. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116768 · Cited by 221 · see citing works
Imparl-Radosevich, J. M., Deas, S., Polansky, M. M., Baedke, D. A., Ingebritsen, T. S., Anderson, R. A., & Graves, D. J. (1998) · Hormone Research in Paediatrics · doi:10.1159/000023270 · Cited by 205 · see citing works
Insulin potentiating factor and chromium content of selected foods and spices
Khan, A., Bryden, N. A., Polansky, M. M., & Anderson, R. A. (1990) · Biological Trace Element Research · doi:10.1007/bf02917206 · Cited by 171 · see citing works
Chericoni, S., Prieto, J. M., Iacopini, P., Cioni, P., & Morelli, I. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf050183e · Cited by 123 · see citing works
Tests of Glycemia in Diabetes Mellitus
Singer, D. E., Coley, C. M., Samet, J. H., & Nathan, D. M. (1989) · Annals of Internal Medicine · doi:10.7326/0003-4819-110-2-125 · Cited by 77 · see citing works
Alberti (1998) · doi:10.1002/(sici)1096-9136(199807)15:7
Flagged first, then by citations
1 of the 21 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Health benefits of herbs and spices: the past, the present, the future
Tapsell, L. C., Hemphill, I., Cobiac, L., SULLIVAN, D. R., Fenech, M. F., Patch, C. S., Roodenrys, S. J., Keogh, J. B., Clifton, P. M., Williams, P., et al. (2006) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2006.tb00548.x · Cited by 989 · see citing works
Cinnamon: A Multifaceted Medicinal Plant
Pasupuleti, V. R., & Gan, S. H. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/642942 · Cited by 844 · see citing works
Antidiabetic Potential of Medicinal Plants and Their Active Components
Salehi, B., Ata, A., Kumar, N. V. A., Sharopov, F. S., Ramírez‐Alarcón, K., Ruíz-Ortega, A. M., Ayatollahi, S. A., Fokou, P. V. T., Kobarfard, F., Zakaria, Z. A., et al. (2019) · Biomolecules · doi:10.3390/biom9100551 · Cited by 750 · see citing works
Polyphenols and Glycemic Control
Kim, Y., Keogh, J. B., & Clifton, P. M. (2016) · Nutrients · doi:10.3390/nu8010017 · Cited by 557 · see citing works
Natural Products for the Treatment of Type 2 Diabetes Mellitus
Rı́os, J. L., Francini, F., & Schinella, G. R. (2015) · Planta Medica · doi:10.1055/s-0035-1546131 · Cited by 447 · see citing works
Gruenwald, J., Freder, J., & Armbruester, N. (2010) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390902773052 · Cited by 356 · see citing works
Cao, H., Polansky, M. M., & Anderson, R. A. (2007) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2006.12.034 · Cited by 272 · see citing works
Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis
Allen, R. W., Schwartzman, E., Baker, W. L., Coleman, C. I., & Phung, O. J. (2013) · The Annals of Family Medicine · doi:10.1370/afm.1517 · Cited by 269 · see citing works
“2 g/d was associated with an increase in fasting plasma glucose levels,10,14 and hemoglobin A1c levels9,10; however, others have reported reductions in glycemic parameters at doses between 1 to 6 g/d6-9,12,13 and in hemoglobin A1c.(6-9,11-13) The same conflict occurs in lipid parameters, at 1 g/d total cholesterol,10…”
BackgroundCrawford, P. F. (2009) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2009.05.080093 · Cited by 247 · see citing works
Akilen, R., Tsiami, A., Devendra, D., & Robinson, N. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03079.x · Cited by 230 · see citing works
Ziegenfuss, T. N., Hofheins, J. E., Mendel, R. W., Landis, J. A., & Anderson, R. A. (2006) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-3-2-45 · Cited by 231 · see citing works
Qin, B., Panickar, K. S., & Anderson, R. A. (2010) · Journal of Diabetes Science and Technology · doi:10.1177/193229681000400324 · Cited by 220 · see citing works
How Effective Are Antioxidant Supplements in Obesity and Diabetes?
Abdali, D., Samson, S. E., & Grover, A. K. (2015) · Medical Principles and Practice · doi:10.1159/000375305 · Cited by 211 · see citing works
Roussel, A., Hininger‐Favier, I., Benaraba, R., Ziegenfuss, T. N., & Anderson, R. A. (2009) · Journal of the American College of Nutrition · doi:10.1080/07315724.2009.10719756 · Cited by 210 · see citing works
Gut Microbiota, Host Organism, and Diet Trialogue in Diabetes and Obesity
Lazăr, V., Diţu, L.-M., Pîrcălăbioru, G. G., Picu, A. A., Petcu, L. M., Cucu, N., & Chifiriuc, M. C. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00021 · Cited by 207 · see citing works
Azimi, P., Ghiasvand, R., Feizi, A., Hariri, M., & Abbasi, B. (2014) · The Review of Diabetic Studies · doi:10.1900/rds.2014.11.258 · Cited by 203 · see citing works
Papakonstantinou, E., Oikonomou, C., Nychas, G., & Dimitriadis, G. D. (2022) · Nutrients · doi:10.3390/nu14040823 · Cited by 199 · see citing works
Zare, R., Nadjarzadeh, A., Zarshenas, M. M., Shams, M., & Heydari, M. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2018.03.003 · Cited by 188 · see citing works
Sharifi-Rad, J., Dey, A., Koirala, N., Shaheen, S., El Omari, N., Salehi, B., Goloshvili, T., Cirone Silva, N. C., Bouyahya, A., Vitalini, S., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.600139 · Cited by 183 · see citing works
The glycaemic outcomes of Cinnamon, a review of the experimental evidence and clinical trials
Medagama, A. B. (2015) · Nutrition Journal · doi:10.1186/s12937-015-0098-9 · Cited by 183 · see citing works
Lu, T., Sheng, H., Wu, J., Cheng, Y., Zhu, J., & Chen, Y. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.05.003 · Cited by 178 · see citing works
Effect of Cinnamon on Glucose Control and Lipid Parameters
Baker, W. L., Gutierrez-Williams, G., White, C. M., Kluger, J., & Coleman, C. I. (2007) · Diabetes Care · doi:10.2337/dc07-1711 · Cited by 166 · see citing works
Askari, F., Rashidkhani, B., & Hekmatdoost, A. (2013) · Nutrition Research · doi:10.1016/j.nutres.2013.11.005 · Cited by 164 · see citing works
Chromium and polyphenols from cinnamon improve insulin sensitivity
Anderson, R. A. (2008) · Proceedings of The Nutrition Society · doi:10.1017/s0029665108006010 · Cited by 164 · see citing works
Inhibition of Protein Glycation by Extracts of Culinary Herbs and Spices
Dearlove, R. P., Greenspan, P., Hartle, D. K., Swanson, R. B., & Hargrove, J. L. (2008) · Journal of Medicinal Food · doi:10.1089/jmf.2007.536 · Cited by 157 · see citing works
Spices in the management of diabetes mellitus
Bi, X., Lim, J. C. L., & Henry, C. J. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.08.111 · Cited by 153 · see citing works
Hlebowicz, J., Hlebowicz, A., Lindstedt, S., Björgell, O., Höglund, P., Holst, J. J., Darwiche, G., & Almér, L. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26807 · Cited by 146 · see citing works
Potenza, M. V., & Mechanick, J. I. (2009) · Nutrition in Clinical Practice · doi:10.1177/0884533609342436 · Cited by 145 · see citing works
Medagama, A. B., & Bandara, R. (2014) · Nutrition Journal · doi:10.1186/1475-2891-13-102 · Cited by 140 · see citing works
Dugoua, J.-J., Seely, D., Perri, D., Cooley, K., Forrelli, T., Mills, E. J., & Koren, G. (2007) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y07-080 · Cited by 139 · see citing works
Cinnamon effects on metabolic syndrome: a review based on its mechanisms.
Mollazadeh, H., & Hosseinzadeh, H. (2016) · Europe PMC (PubMed Central) · doi:10.22038/ijbms.2016.7906 · Cited by 145 · see citing works
Cinnamon: A systematic review of adverse events
Hajimonfarednejad, M., Ostovar, M., Raee, M. J., Hashempur, M. H., Mayer, J. G., & Heydari, M. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.03.013 · Cited by 136 · see citing works
Polyphenols: Planting the seeds of treatment for the metabolic syndrome
Cherniack, E. P. (2011) · Nutrition · doi:10.1016/j.nut.2010.10.013 · Cited by 127 · see citing works
Cinnamon in glycaemic control: Systematic review and meta analysis
Akilen, R., Tsiami, A., Devendra, D., & Robinson, N. (2012) · Clinical Nutrition · doi:10.1016/j.clnu.2012.04.003 · Cited by 124 · see citing works
Cinnamon Intake Lowers Fasting Blood Glucose: Meta-Analysis
Davis, P. A., & YOKOYAMA, W. H. (2011) · Journal of Medicinal Food · doi:10.1089/jmf.2010.0180 · Cited by 123 · see citing works
The Effect of Cinnamon on A1C Among Adolescents With Type 1 Diabetes
Altschuler, J. A., Casella, S. J., MacKenzie, T. A., & Curtis, K. M. (2007) · Diabetes Care · doi:10.2337/dc06-1871 · Cited by 122 · see citing works
Cinnamon for diabetes mellitus
Leach, M., & Kumar, S. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007170.pub2 · Cited by 121 · see citing works
Vafa, M., Mohammadi, F., Shidfar, F., Sormaghi, M. H. S., Heidari, I., Golestan, B., & Amiri, F. (2012) · PubMed Central · Cited by 121 · see citing works
Effects of short‐term cinnamon ingestion on in vivo glucose tolerance
Solomon, T. P. J., & Blannin, A. K. (2007) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2006.00694.x · Cited by 119 · see citing works
Gupta Jain, S., Puri, S., Misra, A., Gulati, S., & Mani, K. (2017) · Lipids in Health and Disease · doi:10.1186/s12944-017-0504-8 · Cited by 115 · see citing works
Cao, H., Graves, D. J., & Anderson, R. A. (2010) · Phytomedicine · doi:10.1016/j.phymed.2010.03.023 · Cited by 112 · see citing works
Tang, M., Larson‐Meyer, D. E., & Liebman, M. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.5.1262 · Cited by 111 · see citing works
Do Cinnamon Supplements Have a Role in Glycemic Control in Type 2 Diabetes? A Narrative Review
Costello, R. B., Dwyer, J. T., Saldanha, L. G., Bailey, R. L., Merkel, J. M., & Wambogo, E. A. (2016) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2016.07.015 · Cited by 113 · see citing works
Shen, Y., Honma, N., Kobayashi, K., Jia, L. N., Hosono, T., Shindo, K., Ariga, T., & Seki, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087894 · Cited by 107 · see citing works
Hariri, M., & Ghiasvand, R. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-41342-6_1 · Cited by 107 · see citing works
The use of complementary and alternative medicine among people living with diabetes in Sydney
Manya, K., Champion, B. L., & Dunning, T. L. (2012) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-12-2 · Cited by 103 · see citing works
Bioactivity of cinnamon with special emphasis on diabetes mellitus: A review
Bandara, T., Uluwaduge, I., & Jansz, E. R. (2011) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2011.627849 · Cited by 102 · see citing works
Kirkham, S., Akilen, R., Sharma, S., & Tsiami, A. (2009) · Diabetes, obesity and metabolism · doi:10.1111/j.1463-1326.2009.01094.x · Cited by 101 · see citing works
Davari, M., Hashemi, R., Mirmiran, P., Hedayati, M., Sahranavard, S., Bahreini, S., Tavakoly, R., & Talaei, B. (2020) · Nutrition Journal · doi:10.1186/s12937-019-0518-3 · Cited by 97 · see citing works
Beejmohun, V., Peytavy-Izard, M., Mignon, C., Muscente-Paque, D., Deplanque, X., Ripoll, C., & Chapal, N. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-351 · Cited by 97 · see citing works
Silva, M. L., Bernardo, A., Singh, J., & de Mesquita, M. F. (2022) · Nutrients · doi:10.3390/nu14132773 · Cited by 96 · see citing works
Chen, P. C., Sun, J., & Ford, P. W. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf405580c · Cited by 90 · see citing works
Deyno, S., Eneyew, K., Seyfe, S., Tuyiringire, N., Peter, E. L., Muluye, R. A., Tolo, C. U., & Ogwang, P. E. (2019) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2019.107815 · Cited by 95 · see citing works
Shen, Y., Jia, L.-N., Honma, N., Hosono, T., ARIGA, T., & Seki, T. (2012) · Journal of Traditional and Complementary Medicine · doi:10.1016/s2225-4110(16)30067-0 · Cited by 90 · see citing works
Solomon, T. P. J., & Blannin, A. K. (2009) · European Journal of Applied Physiology · doi:10.1007/s00421-009-0986-9 · Cited by 89 · see citing works
Potential therapeutic value of TRPV1 and TRPA1 in diabetes mellitus and obesity
Derbenev, A. V., & Zsombok, A. (2015) · Seminars in Immunopathology · doi:10.1007/s00281-015-0529-x · Cited by 89 · see citing works
Talaei, B., Amouzegar, A., Sahranavard, S., Hedayati, M., Mirmiran, P., & Azizi, F. (2017) · Nutrients · doi:10.3390/nu9090991 · Cited by 82 · see citing works
“reported that cinnamon supplementation had no beneficial effects on fasting blood glucose (FPG) or insulin concentrations [17].”
BackgroundLee, S.-C., Xu, W., Lin, L.-Y., Yang, J.-J., & Liu, C. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf401039z · Cited by 82 · see citing works
Mirfeizi, M., Tourzani, Z. M., Mirfeizi, S. Z., Jafarabadi, M. A., Rezvani, H. R., & Afzali, M. (2015) · Journal of Diabetes · doi:10.1111/1753-0407.12342 · Cited by 82 · see citing works
Maierean, S. M., Șerban, M.-C., Sahebkar, A., Ursoniu, S., Serban, A., Penson, P. E., & Banach, M. (2017) · Journal of clinical lipidology · doi:10.1016/j.jacl.2017.08.004 · Cited by 84 · see citing works
Namazi, N., Khodamoradi, K., Khamechi, S. P., Heshmati, J., Ayati, M. H., & Larijani, B. A. (2019) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.01.002 · Cited by 76 · see citing works
Chen, L., Sun, P. G., Wang, T., Chen, K., Jia, Q., Wang, H., & Li, Y. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf3024535 · Cited by 73 · see citing works
Farrell, T. L., Sutulic, S., Forrelli, T., & Williamson, G. (2013) · BioFactors · doi:10.1002/biof.1090 · Cited by 72 · see citing works
Controversies surrounding the clinical potential of cinnamon for the management of diabetes
Rafehi, H., Ververis, K., & Karagiannis, T. C. (2011) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2011.01538.x · Cited by 72 · see citing works
The Effect of Cinnamon on Glucose of Type II Diabetes Patients
Hasanzade, F., Toliat, M., Emami, S. A., & Emamimoghaadam, Z. (2013) · Journal of Traditional and Complementary Medicine · doi:10.4103/2225-4110.114900 · Cited by 69 · see citing works
Palma-Duran, S. A., Vlassopoulos, A., Lean, M. E. J., Govan, L., & Combet, E. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2014.973932 · Cited by 66 · see citing works
A Reason to Season: The Therapeutic Benefits of Spices and Culinary Herbs
Dog, T. L. (2006) · EXPLORE · doi:10.1016/j.explore.2006.06.010 · Cited by 61 · see citing works
To what extent does cinnamon administration improve the glycemic and lipid profiles?
Santos, H. O., & da Silva, G. A. R. (2018) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2018.07.011 · Cited by 61 · see citing works
Role of spices in the treatment of diabetes mellitus: A minireview
Şanlıer, N., & Bingöl, F. G. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.03.018 · Cited by 61 · see citing works
Cinnamon: The historic spice, medicinal uses, and flavour chemistry
Spence, C. J. (2023) · International Journal of Gastronomy and Food Science · doi:10.1016/j.ijgfs.2023.100858 · Cited by 60 · see citing works
A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements
Deng, R. (2012) · Recent Patents on Food Nutrition & Agriculture · doi:10.2174/1876142911204010050 · Cited by 61 · see citing works
Functional foods for health: Focus on diabetes
Rudkowska, I. (2009) · Maturitas · doi:10.1016/j.maturitas.2009.01.011 · Cited by 58 · see citing works
Cinnamon Supplementation in Patients with Type 2 Diabetes Mellitus
Pham, A. Q., Kourlas, H., & Pham, D. Q. (2007) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.27.4.595 · Cited by 56 · see citing works
Nikzamir, A., Palangi, A., Kheirollaha, A., Tabar, H., Malakaskar, A., Shahbazian, H. B., & Fathi, M. (2014) · Iranian Red Crescent Medical Journal · doi:10.5812/ircmj.13426 · Cited by 53 · see citing works
Sengsuk, C., Sanguanwong, S., Tangvarasittichai, O., & Tangvarasittichai, S. (2015) · Diabetology International · doi:10.1007/s13340-015-0218-y · Cited by 52 · see citing works
Potential health benefits of Indian spices in the symptoms of the metabolic syndrome: a review.
Iyer, A., Panchal, S. K., Poudyal, H., & Brown, L. (2009) · PubMed · Cited by 51 · see citing works
Use of Complementary and Alternative Medicine Supplements in Patients with Diabetes Mellitus
Fabian, E., Töscher, S., Elmadfa, I., & Pieber, T. R. (2011) · Annals of Nutrition and Metabolism · doi:10.1159/000326765 · Cited by 50 · see citing works
TRP Channels as Therapeutic Targets in Diabetes and Obesity
Zsombok, A., & Derbenev, A. V. (2016) · Pharmaceuticals · doi:10.3390/ph9030050 · Cited by 50 · see citing works
Dietary Supplements in the Management of Diabetes: Potential Risks and Benefits
Geil, P., & Shane‐McWhorter, L. (2008) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2008.01.020 · Cited by 50 · see citing works
Effects of the polyphenol content on the anti-diabetic activity of Cinnamomum zeylanicum extracts
Krishnakumar, I. M., Issac, A., Johannah, N. M., Ninan, E., Maliakel, B. P., & Kuttan, R. (2014) · Food & Function · doi:10.1039/c4fo00130c · Cited by 49 · see citing works
Moridpour, A. H., Kavyani, Z., Khosravi, S., Farmani, E., Daneshvar, M., Musazadeh, V., & Faghfouri, A. H. (2023) · Phytotherapy Research · doi:10.1002/ptr.8026 · Cited by 54 · see citing works
Ulbricht, C. E., Seamon, E., Windsor, R. C., Armbruester, N., Bryan, J. K., Costa, D., Giese, N., Gruenwald, J., Iovin, R. C., Isaac, R., et al. (2011) · Journal of Dietary Supplements · doi:10.3109/19390211.2011.627783 · Cited by 48 · see citing works
Sun, P. G., Wang, T., Chen, L., Yu, B., Jia, Q., Chen, K., Fan, H., Li, Y., & Wang, H. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.29 · Cited by 43 · see citing works
Mahdavi, A., Bagherniya, M., Mirenayat, M. S., Atkin, S. L., & Sahebkar, A. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-64872-5_13 · Cited by 44 · see citing works
Herbals Used for Diabetes, Obesity, and Metabolic Syndrome
Najm, W. I., & Lie, D. (2010) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2010.02.008 · Cited by 42 · see citing works
Chase, C. K., & McQueen, C. E. (2007) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp060538 · Cited by 41 · see citing works
Rachid, A. P., Moncada, M. M., de Mesquita, M. F., Brito, J., Bernardo, A., & Silva, M. L. (2022) · Nutrients · doi:10.3390/nu14081576 · Cited by 42 · see citing works
Enhanced anti-diabetic activity of polyphenol-rich de-coumarinated extracts of Cinnamomum cassia
Kumar, K., Issac, A., Ninan, E., Kuttan, R., & Maliakel, B. P. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.05.008 · Cited by 37 · see citing works
Health benefits of herbs and spices
Kurian, A. (2012) · Elsevier eBooks · doi:10.1533/9780857095688.72 · Cited by 37 · see citing works
Wickenberg, J., Lindstedt, S., Berntorp, K., Nilsson, J., & Hlebowicz, J. (2012) · British Journal of Nutrition · doi:10.1017/s0007114511005113 · Cited by 34 · see citing works
Wu, Z., Weng, S., Yan, D., Xie, Z.-J., Zhou, Q., Li, H., Bai, B.-L., Boodhun, V., Shen, Z., Tang, J., et al. (2018) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2018.09.002 · Cited by 35 · see citing works
Mackonochie, M., Rodriguez‐Mateos, A., Mills, S. Y., & Rolfe, V. E. (2023) · Nutrients · doi:10.3390/nu15234867 · Cited by 39 · see citing works
Kızılaslan, N., & Erdem, N. Z. (2019) · International Journal of Food Science · doi:10.1155/2019/4138534 · Cited by 33 · see citing works
Farrokhfall, K., Khoshbaten, A., Zahediasl, S., Mehrani, H. A., & Karbalaei, N. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.07.014 · Cited by 33 · see citing works
Garza, M. C., Pérez‐Calahorra, S., Rodrigo‐Carbó, C., Sánchez-Calavera, M. A., Jarauta, E., Mateo‐Gállego, R., Gracia‐Rubio, I., & Lamíquiz-Moneo, I. (2024) · Nutrients · doi:10.3390/nu16060756 · Cited by 32 · see citing works
Effects of cinnamaldehyde on the glucose transport activity of GLUT1
Rosenberger, C. L., Cok, A., Scott, J., Opejin, A., Bushhouse, K. T., Salie, M. J., & Louters, L. L. (2010) · Biochimie · doi:10.1016/j.biochi.2010.10.006 · Cited by 32 · see citing works
Algorithm for Complementary and Alternative Medicine Practice and Research in Type 2 Diabetes
Bradley, R. D., Oberg, E. B., Calabrese, C., & Standish, L. J. (2007) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2006.6207 · Cited by 30 · see citing works
Potential treatments for insulin resistance in the horse: A comparative multi-species review
Tinworth, K. D., Harris, P. A., Sillence, M. N., & Noble, G. K. (2009) · The Veterinary Journal · doi:10.1016/j.tvjl.2009.08.032 · Cited by 30 · see citing works
Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols
Ge, Q., Chen, L., & Chen, K.-P. (2017) · Journal of Diabetes Research · doi:10.1155/2017/5837804 · Cited by 27 · see citing works
Shinjyo, N., Waddell, G., & Green, J. (2020) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2020.100342 · Cited by 30 · see citing works
- Authors
- Vanschoonbeek, K., Thomassen, B. J., Senden, J. M., Wodzig, W. K., & van Loon, L. J.
- Affiliations
- Maastricht University (NL)
- Maastricht University Medical Centre (NL)
- Corresponding author
- Vanschoonbeek, Kristof
- Venue
- The Journal of Nutrition
- Publisher
- Elsevier BV
- Published
- 2006-04
- Volume
- 136
- Issue
- 4
- Pages
- 977-980
- ISSN
- 0022-3166 (ISSN-L)
- OpenAlex
- W2095773990
- Cited by
- 241
- References
- 21
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 14 · 2023: 9 · 2022: 12 · 2021: 16 · 2020: 18 · 2019: 12 · 2018: 7 · 2017: 9 · 2016: 16 · 2015: 11 · 2014: 14 · 2013: 11 · 2012: 14
- FWCI
- 9.96
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Pharmacology › Berberine and alkaloids research
- Keywords
- cinnamon supplementation, Cinnamomum cassia, type 2 diabetes, postmenopausal women, glycemic control, insulin sensitivity, oral glucose tolerance, lipid profile, fasting blood glucose
- MeSH terms
- Blood Glucose, Energy Intake, Cinnamomum zeylanicum, Diabetes Mellitus, Type 2, Double-Blind Method, Fasting, Female, Glucose Tolerance Test, Glycated Hemoglobin, Humans, Insulin, Insulin Resistance, Lipids, Middle Aged, Placebos, Body Mass Index, Postmenopause, Dietary Supplements
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