Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits
Open accessAbstract
The genus Cinnamomum includes a number of plant species largely used as food, food additives and spices for a long time. Different traditional healing systems have used these plants as herbal remedies to cure diverse ailments. The aim of this comprehensive and updated review is to summarize the biodiversity of the genus Cinnamomum , its bioactive compounds, the mechanisms that underlie the pharmacological activities and molecular targets and toxicological safety. All the data in this review have been collected from databases and recent scientific literature including Web of Science, PubMed, ScienceDirect etc. The results showed that the bioactive compounds of Cinnamomum species possess antimicrobial, antidiabetic, antioxidant, anti-inflammatory, anticancer and neuroprotective effects. The preclinical ( in vitro / in vivo ) studies provided the possible molecular mechanisms of these action. As a novelty, recent clinical studies and toxicological data described in this paper support and confirm the pharmacological importance of the genus Cinnamomum. In conclusion, the obtained results from preclinical studies and clinical trials, as well as reduced side effects provide insights into future research of new drugs based on extracts and bioactive compounds from Cinnamomum plants.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Phytochemicals rarely fit the ideal drug-like profile due to their scarce bioavailability; therefore, their manipulation also aims to ameliorate their pharmacokinetics.
“However, phytochemicals rarely fit in the ideal drug-like profile due to their scarce bioavailability; therefore, their manipulation also aims to ameliorate their pharmacokinetics [210,211].”
From Multi-Target Mechanisms of Phytochemicals in Alzheimer’s Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation (2022) · cites this paper as [210]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
1 retracted
Anti-Inflammatory Activities ofCinnamomum cassiaConstituentsIn VitroandIn Vivo
Liao, J., Deng, J., Chiu, C., Hou, W., Huang, S., Shie, P.-H., & Huang, G.-J. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/429320 · Cited by 214 · see citing works
RetractedWild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004) · Diabetes Care · doi:10.2337/diacare.27.5.1047 · Cited by 15,297 · see citing works
Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections
King, H. O. M., Aubert, R. E., & Herman, W. H. (1998) · Diabetes Care · doi:10.2337/diacare.21.9.1414 · Cited by 6,267 · see citing works
Neuroinflammation in Alzheimer's disease
Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)70016-5 · Cited by 6,226 · see citing works
Global and societal implications of the diabetes epidemic
Zimmet, P., Alberti, K. G. M. M., & Shaw, J. (2001) · Nature · doi:10.1038/414782a · Cited by 5,883 · see citing works
Mechanisms linking obesity to insulin resistance and type 2 diabetes
Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006) · Nature · doi:10.1038/nature05482 · Cited by 5,448 · see citing works
Lambert, R. J. W., Skandamis, P. N., Coote, P. J., & Nychas, G.-J. E. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01428.x · Cited by 2,449 · see citing works
Pathogenesis of NIDDM. A balanced overview.
DeFronzo, R. A., Bonadonna, R. C., & Ferrannini, E. (1992) · Diabetes Care · doi:10.2337/diacare.15.3.318 · Cited by 2,085 · see citing works
Sharifi-Rad, M., Anil Kumar, N. V., Zucca, P., Varoni, E. M., Dini, L., Panzarini, E., Rajkovic, J., Tsouh Fokou, P. V., Azzini, E., Peluso, I., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00694 · Cited by 1,971 · see citing works
Self-citationHu, F. B. (2011) · Diabetes Care · doi:10.2337/dc11-0442 · Cited by 1,954 · see citing works
Characterization of the action of selected essential oil components on Gram-negative bacteria
Helander, I. M., Alakomi, H.-L., Latva-Kala, K., Mattila-Sandholm, T., Pol, I., Smid, E. J., Gorris, L. G. M., & von Wright, A. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf980154m · Cited by 1,664 · see citing works
Calixto, J. Β. (2000) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2000000200004 · Cited by 1,283 · see citing works
Antibacterial Activity and Mode of Action of Ferulic and Gallic Acids Against Pathogenic Bacteria
Borges, A. D. S., Ferreira, C., Saavedra, M. J., & Simões, M. V. (2013) · Microbial Drug Resistance · doi:10.1089/mdr.2012.0244 · Cited by 1,275 · see citing works
Impact of Dietary Polyphenols on Carbohydrate Metabolism
Hanhineva, K., Törrönen, R., Bondia‐Pons, I., Pekkinen, J., Kolehmainen, M., Mykkänen, H. M., & Poutanen, K. S. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11041365 · Cited by 1,167 · see citing works
Antidiabetic plants and their active constituents
Marles, R. J., & Farnsworth, N. R. (1995) · Phytomedicine · doi:10.1016/s0944-7113(11)80059-0 · Cited by 1,105 · see citing works
Cinnamon improves glucose and lipids of people with type 2 diabetes
Khan, A., Safdar, M., Ali Khan, M. M., Khattak, K. N., & Anderson, R. A. (2003) · Diabetes Care · doi:10.2337/diacare.26.12.3215 · Cited by 981 · see citing works
Carson, C. F., Mee, B. J., & Riley, T. V. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.6.1914-1920.2002 · Cited by 975 · see citing works
Cinnamon: A Multifaceted Medicinal Plant
Pasupuleti, V. R., & Gan, S. H. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/642942 · Cited by 844 · see citing works
Mechanisms of Action of Carvacrol on the Food-Borne Pathogen <i>Bacillus cereus</i>
Ultee, A., Kets, E. P. W., & Smid, E. J. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.10.4606-4610.1999 · Cited by 781 · see citing works
Singh, G., Maurya, S., deLampasona, M., & Catalán, C. A. N. (2007) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.02.031 · Cited by 663 · see citing works
Membrane toxicity of antimicrobial compounds from essential oils
Di Pasqua, R., Betts, G., Hoskins, N., Edwards, M., Ercolini, D., & Mauriello, G. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0636465 · Cited by 648 · see citing works
Kar, A., Choudhary, B. K., & Bandyopadhyay, N. (2003) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(02)00144-7 · Cited by 644 · see citing works
Ranilla, L. G., Kwon, Y., Apostolidis, E., & Shetty, K. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.01.093 · Cited by 643 · see citing works
Antibacterial activity of leaf essential oils and their constituents from Cinnamomum osmophloeum
Chang, S.-T., Chen, P.-F., & Chang, S.-C. (2001) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(01)00273-2 · Cited by 514 · see citing works
Cinnamaldehyde--a potential antidiabetic agent
Subash Babu, P., Prabuseenivasan, S., & Ignacimuthu, S. (2007) · Phytomedicine · doi:10.1016/j.phymed.2006.11.005 · Cited by 477 · see citing works
Screening for Inhibitory Activity of Essential Oils on Selected Bacteria, Fungi and Viruses
Chao, S. C., Young, D. G., & Oberg, C. J. (2000) · Journal of Essential Oil Research · doi:10.1080/10412905.2000.9712177 · Cited by 433 · see citing works
Vallverdú‐Queralt, A., Regueiro, J., Martínez‐Huélamo, M., de Alvarenga, J. F. R., Leal, L. N., & Lamuela-Raventós, R. M. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2013.12.106 · Cited by 399 · see citing works
Mathew, S., & Abraham, T. E. (2005) · Food Chemistry · doi:10.1016/j.foodchem.2004.11.043 · Cited by 372 · see citing works
Shan, B., Cai, Y., Brooks, J. D., & Corke, H. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf070424d · Cited by 364 · see citing works
Unlu, M., Ergene, E., Vardar‐Ünlü, G., Zeytinoglu, H. S., & Vural, N. (2010) · Food and Chemical Toxicology · doi:10.1016/j.fct.2010.09.001 · Cited by 364 · see citing works
Mang, B., Wolters, M., Schmitt, B., Kelb, K., Lichtinghagen, R., Stichtenoth, D. O., & Hahn, A. (2006) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2006.01629.x · Cited by 354 · see citing works
Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts
Atta, A. H., & Alkofahi, A. (1998) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(97)00137-2 · Cited by 341 · see citing works
Skandamis, P. N., & Nychas, G. E. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01467.x · Cited by 341 · see citing works
Ooi, L. S. M., Li, Y.-L., Kam, S.-L., et al. (2006) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x06004041 · Cited by 337 · see citing works
Determining the Antimicrobial Actions of Tea Tree Oil
Cox, S. D., Mann, C. M., Markham, J. L., Gustafson, J. E., Warmington, J. R., & Wyllie, S. G. (2001) · Molecules · doi:10.3390/60100087 · Cited by 311 · see citing works
Oussalah, M., Caillet, S., Saucier, L., & Lacroix, M. (2006) · Meat Science · doi:10.1016/j.meatsci.2005.11.019 · Cited by 307 · see citing works
Wang, R., Wang, R., & Yang, B. J. (2008) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2008.12.002 · Cited by 302 · see citing works
Sharifi‐Rad, J., Rodrigues, C. F., Sharopov, F. S., Docea, A. O., Karaça, A. C., Sharifi‐Rad, M., Kahveci, D., Gülseren, G., Şenol, E., Demircan, E., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17072326 · Cited by 295 · see citing works
Self-citationSalehi, B., Sharifi-Rad, J., Cappellini, F., Reiner, Ž., Zorzan, D., Imran, M., Sener, B., Kilic, M., El-Shazly, M., Fahmy, N. M., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01300 · Cited by 293 · see citing works
Self-citationToxicology and risk assessment of coumarin: Focus on human data
Abraham, K., Wöhrlin, F., Lindtner, O., Heinemeyer, G., & Lampen, A. (2010) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200900281 · Cited by 292 · see citing works
Peng, X., Cheng, K., Ma, J., Chen, B., Ho, C., Lo, C., Chen, F., & Wang, M. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf073065v · Cited by 263 · see citing works
Antibacterial properties of essential oils from Thai medicinal plants
Wannissorn, B., Jarikasem, S., Siriwangchai, T., & Thubthimthed, S. (2005) · Fitoterapia · doi:10.1016/j.fitote.2004.12.009 · Cited by 258 · see citing works
Anti-fungal and anti-bacterial activity of some herbal remedies from Tanzania
de Boer, H., Kool, A., Broberg, A., et al. (2004) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2004.09.035 · Cited by 251 · see citing works
Ortíz-Andrade, R., García-Jiménez, S., Castillo-España, P., Ramírez-Ávila, G., Villalobos-Molina, R., & Estrada-Soto, S. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2006.07.002 · Cited by 251 · see citing works
Crawford, P. F. (2009) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2009.05.080093 · Cited by 247 · see citing works
Flavonoid contents and antioxidant activities from Cinnamomum species
Prasad, K. N., Yang, B. J., Dong, X., Jiang, G., Zhang, H., Xie, H., & Jiang, Y. (2009) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2009.05.009 · Cited by 242 · see citing works
Rhayour, K., Bouchikhi, T., Tantaoui‐Elaraki, A., Sendide, K., & Remmal, A. (2003) · Journal of Essential Oil Research · doi:10.1080/10412905.2003.9698611 · Cited by 241 · see citing works
Vanschoonbeek, K., Thomassen, B. J., Senden, J. M., Wodzig, W. K., & van Loon, L. J. (2006) · The Journal of Nutrition · doi:10.1093/jn/136.4.977 · Cited by 241 · see citing works
In vitro anti-inflammatory and anti-oxidative effects of Cinnamomum camphora extracts
Lee, H. J., Hyun, E.-A., Yoon, W., et al. (2005) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2005.08.009 · Cited by 234 · see citing works
Akilen, R., Tsiami, A., Devendra, D., & Robinson, N. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03079.x · Cited by 230 · see citing works
Antioxidant activities of ethanolic extracts from the twigs of Cinnamomum osmophloeum
Chua, M.-T., Tung, Y., & Chang, S. (2007) · Bioresource Technology · doi:10.1016/j.biortech.2007.03.020 · Cited by 222 · see citing works
Effect of cinnamon on glucose and lipid levels in non insulin-dependent type 2 diabetes
Blevins, S. M., Leyva, M. J., Brown, J., Wright, J., Scofield, R. H., & Aston, C. E. (2007) · Diabetes Care · doi:10.2337/dc07-0098 · Cited by 221 · see citing works
Koppikar, S. J., Choudhari, A. S., Suryavanshi, S., Kumari, S., Chattopadhyay, S., & Kaul-Ghanekar, R. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-210 · Cited by 220 · see citing works
Qin, B., Panickar, K. S., & Anderson, R. A. (2010) · Journal of Diabetes Science and Technology · doi:10.1177/193229681000400324 · Cited by 220 · see citing works
Revisiting an ancient spice with medicinal purposes: Cinnamon
Ribeiro‐Santos, R., Andrade, M. A., Madella, D. K. S. F., Martinazzo, A. P., Moura, L. D. A. G., de Melo, N. R., & Sanches-Silva, A. T. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.02.011 · Cited by 220 · see citing works
Roussel, A., Hininger‐Favier, I., Benaraba, R., Ziegenfuss, T. N., & Anderson, R. A. (2009) · Journal of the American College of Nutrition · doi:10.1080/07315724.2009.10719756 · Cited by 210 · see citing works
Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1
Kwon, H., Hwang, J., So, J., Lee, C., Sahoo, A., Ryu, J.-H., Jeon, W. K., Ko, B., Im, C.-R., Lee, S. H., et al. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-392 · Cited by 205 · see citing works
Anand, P., Murali, K. Y., Tandon, V., Murthy, P. S., & Chandra, R. (2010) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2010.03.044 · Cited by 193 · see citing works
Turgis, M., Vu, K. D., Dupont, C., & Lacroix, M. (2012) · Food Research International · doi:10.1016/j.foodres.2012.06.016 · Cited by 188 · see citing works
Liver fibrosis and inflammation. A review
Stalnikowitz, D. K., & Weissbrod, A. B. (2003) · Annals of Hepatology · doi:10.1016/s1665-2681(19)32127-1 · Cited by 183 · see citing works
Volatile Constituents from Cinnamomum zeylanicum Fruit Stalks and Their Antioxidant Activities
Jayaprakasha, G. K., Rao, L. J. M., & Sakariah, K. K. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf034169i · Cited by 182 · see citing works
Antibiotic and biocide resistance in bacteria: Introduction
Russell, A. D. (2002) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.92.5s1.14.x · Cited by 177 · see citing works
Ranasinghe, P. D., Jayawardena, R., Galappaththy, P., Constantine, G. R., Gunawardana, N. D. V., & Katulanda, P. (2012) · Diabetic Medicine · doi:10.1111/j.1464-5491.2012.03718.x · Cited by 176 · see citing works
Latta, C. H., Brothers, H. M., & Wilcock, D. M. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.09.061 · Cited by 176 · see citing works
Anti-cancer effects of cinnamon: Insights into its apoptosis effects
Sadeghi, S., Davoodvandi, A., Pourhanifeh, M. H., et al. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.05.067 · Cited by 176 · see citing works
Wondrak, G. T., Villeneuve, N. F., Lamore, S. D., Bause, A. S., Jiang, T., & Zhang, D. D. (2010) · Molecules · doi:10.3390/molecules15053338 · Cited by 173 · see citing works
Antidiabetic effect ofCinnamomum cassia andCinnamomum zeylanicum In vivo andIn vitro
Verspohl, E. J., Bauer, K., & Neddermann, E. (2005) · Phytotherapy Research · doi:10.1002/ptr.1643 · Cited by 172 · see citing works
Cinnamon extract inhibits tau aggregation associated with Alzheimer’s disease in vitro
Peterson, D. W., George, R. C., Scaramozzino, F., LaPointe, N. E., Anderson, R. A., Graves, D. J., & Lew, J. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1083 · Cited by 171 · see citing works
Adisakwattana, S., Lerdsuwankij, O., Poputtachai, U., Minipun, A., & Suparpprom, C. (2011) · Plant Foods for Human Nutrition · doi:10.1007/s11130-011-0226-4 · Cited by 171 · see citing works
Antioxidant activity of <i>Cinnamomum cassia</i>
Lin, C., Wu, S., Chang, C., & Ng, L. (2003) · Phytotherapy Research · doi:10.1002/ptr.1190 · Cited by 164 · see citing works
Mohamed Sham Shihabudeen, H., Hansi Priscilla, D., & Thirumurugan, K. (2011) · Nutrition & Metabolism · doi:10.1186/1743-7075-8-46 · Cited by 163 · see citing works
Cheng, D. M., Kuhn, P. E., Poulev, A., Rojo, L. E., Lila, M. A., & Raskin, I. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.06.117 · Cited by 160 · see citing works
Cucurbits Plants: A Key Emphasis to Its Pharmacological Potential
Salehi, B., Çapanoğlu, E., Adrar, N., Çatalkaya, G., Shaheen, S., Jaffer, M., Giri, L., Suyal, R., Jugran, A. K., Călina, D. C., et al. (2019) · Molecules · doi:10.3390/molecules24101854 · Cited by 160 · see citing works
Self-citationPhenolic Constituents in the Fruits of Cinnamomum zeylanicum and Their Antioxidant Activity
Jayaprakasha, G. K., Ohnishi‐Kameyama, M., Ono, H., Yoshida, M., & Rao, L. J. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf052736r · Cited by 157 · see citing works
Salehi, B., López‐Jornet, P., Pons-Fuster, E., Călina, D. C., Sharifi‐Rad, M., Ramírez‐Alarcón, K., Forman, K., Fernández, M., Martorell, M., Setzer, W. N., et al. (2019) · Biomolecules · doi:10.3390/biom9030106 · Cited by 155 · see citing works
Self-citationLiao, B., Hsieh, C., Liu, Y., Tzeng, T.-T., Sun, Y.-W., & Wung, B. (2008) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2008.01.021 · Cited by 154 · see citing works
Moselhy, S. S., & ALI, H. K. H. (2009) · Biological Research · doi:10.4067/s0716-97602009000100009 · Cited by 149 · see citing works
Growth-Inhibiting Effects of Cinnamomum cassia Bark-Derived Materials on Human Intestinal Bacteria
Lee, H., & Ahn, Y. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf970548y · Cited by 148 · see citing works
Utchariyakiat, I., Surassmo, S., Jaturanpinyo, M., et al. (2016) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-016-1134-9 · Cited by 146 · see citing works
A Mechanistic and Pathophysiological Approach for Stroke Associated with Drugs of Abuse
Tsatsakis, A. M., Docea, A. O., Călina, D. C., Tsarouhas, K., Zamfira, L.-M., Mitruţ, R., Sharifi‐Rad, J., Kovatsi, L., Siokas, V., Dardiotis, E., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8091295 · Cited by 143 · see citing works
Self-citationYang, C., Li, R., & Chuang, L. (2012) · Molecules · doi:10.3390/molecules17067294 · Cited by 139 · see citing works
Principal phenolic phytochemicals and antioxidant activities of three Chinese medicinal plants
Jang, H.-D., Chang, K., Huang, Y.-S., et al. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.09.026 · Cited by 137 · see citing works
Cinnamon: A systematic review of adverse events
Hajimonfarednejad, M., Ostovar, M., Raee, M. J., Hashempur, M. H., Mayer, J. G., & Heydari, M. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.03.013 · Cited by 136 · see citing works
Agarwal, H., Nakara, A. M., Menon, S. V., et al. (2019) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2019.101212 · Cited by 136 · see citing works
(2003) · CRC Press eBooks · doi:10.1201/9780203590874 · Cited by 135 · see citing works
Azimi, P., Ghiasvand, R., Feizi, A., Hosseinzadeh‐Attar, M. J., Bahreynian, M., Hariri, M., & Khosravi‐Boroujeni, H. (2016) · Blood Pressure · doi:10.3109/08037051.2015.1111020 · Cited by 135 · see citing works
Effects of Cinnamon (Cinnamomum spp.) in Dentistry: A Review
Yanakiev, S. (2020) · Molecules · doi:10.3390/molecules25184184 · Cited by 135 · see citing works
Volatile constituents of cinnamon (Cinnamomum zeylanicum) oils
Senanayake, U. M., Lee, T. H., & Wills, R. B. H. (1978) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf60218a031 · Cited by 131 · see citing works
Antimicrobial activity and brine shrimp toxicity of extracts of Terminalia brownii roots and stem
Mbwambo, Z. H., Moshi, M. J., Masimba, P., et al. (2007) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-7-9 · Cited by 130 · see citing works
Wang, J., Su, B.-Z., Jiang, H., et al. (2020) · Fitoterapia · doi:10.1016/j.fitote.2020.104675 · Cited by 130 · see citing works
Kumar, S. G., Vasudeva, N., & Sharma, S. (2012) · Cardiovascular Diabetology · doi:10.1186/1475-2840-11-95 · Cited by 129 · see citing works
Cinnamon bark extract improves glucose metabolism and lipid profile in the fructose-fed rat.
Kannappan, S., Jayaraman, T., Rajasekar, P., Ravichandran, M. K., & Anuradha, C. V. (2006) · PubMed · Cited by 125 · see citing works
Yang, Y., Lee, H., Lee, S. H., et al. (2005) · International Journal for Parasitology · doi:10.1016/j.ijpara.2005.08.005 · Cited by 125 · see citing works
The Effect of Cinnamon on A1C Among Adolescents With Type 1 Diabetes
Altschuler, J. A., Casella, S. J., MacKenzie, T. A., & Curtis, K. M. (2007) · Diabetes Care · doi:10.2337/dc06-1871 · Cited by 122 · see citing works
Vafa, M., Mohammadi, F., Shidfar, F., Sormaghi, M. H. S., Heidari, I., Golestan, B., & Amiri, F. (2012) · PubMed Central · Cited by 121 · see citing works
Shen, Y., FUKUSHIMA, M., Ito, Y., et al. (2010) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.100453 · Cited by 121 · see citing works
Oxidative Stress and Inflammation Interdependence in Multiple Sclerosis
Pădureanu, R., Albu, C. V., Mititelu, R. R., Bacanoiu, M. V., Docea, A. O., Călina, D. C., Pădureanu, V., Olaru, G., Sandu, R. E., Mălin, R. D., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8111815 · Cited by 120 · see citing works
Self-citationYap, P. S. X., Krishnan, T., Chan, K., & Lim, S. E. (2015) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.1407.07054 · Cited by 118 · see citing works
Antimicrobial activity of ultrasound-assisted solvent-extracted spices
Thongson, C., Davidson, P. M., Mahakarnchanakul, W., et al. (2004) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2004.01605.x · Cited by 118 · see citing works
Suppression of age-related inflammatory NF-κB activation by cinnamaldehyde
Kim, D. H., Kim, C. H., Kim, M. S., Kim, J. Y., Jung, K. J., Chung, J. H., An, W. G., Lee, J., Yu, B. P., & Chung, H. Y. (2007) · Biogerontology · doi:10.1007/s10522-007-9098-2 · Cited by 118 · see citing works
Yeh, R.-Y., Shiu, Y., Shei, S.-C., Cheng, S.-C., Huang, S.-Y., Lin, J., & Liu, C. (2008) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2008.11.008 · Cited by 117 · see citing works
The mechanism of action of oral antidiabetic drugs: A review of recent literature
Bösenberg, L. H., & Zyl, D. G. V. (2008) · Journal of Endocrinology Metabolism and Diabetes of South Africa · doi:10.1080/22201009.2008.10872177 · Cited by 116 · see citing works
Variations in essential oil yield and composition during Cinnamomum cassia bark growth
Geng, S., Cui, Z.-X., Huang, X., Chen, Y., Xu, D., & Xiong, P. (2010) · Industrial Crops and Products · doi:10.1016/j.indcrop.2010.10.018 · Cited by 115 · see citing works
Borzoei, A., Rafraf, M., Niromanesh, S., Farzadi, L., Narimani, F., & Doostan, F. (2017) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2017.04.008 · Cited by 115 · see citing works
LEITER, L., & Lewanczuk, R. Z. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2004.07.001 · Cited by 114 · see citing works
Hajimonfarednejad, M., Nimrouzi, M., Heydari, M., Zarshenas, M. M., Raee, M. J., & Jahromi, B. N. (2017) · Phytotherapy Research · doi:10.1002/ptr.5970 · Cited by 114 · see citing works
Lu, Z., Jia, Q., Wang, R., Wu, X., Wu, Y., Huang, C., & Li, Y. (2010) · Phytomedicine · doi:10.1016/j.phymed.2010.08.008 · Cited by 113 · see citing works
Pro‐healing effect of Cinnamomum zeylanicum bark
Kamath, J. V., Rana, A. C., & Chowdhury, A. R. (2003) · Phytotherapy Research · doi:10.1002/ptr.1293 · Cited by 112 · see citing works
Wang, H., Chen, C., & Wen, Z. (2010) · Experimental Dermatology · doi:10.1111/j.1600-0625.2010.01161.x · Cited by 111 · see citing works
Kort, D. H., & Lobo, R. A. (2014) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2014.05.009 · Cited by 111 · see citing works
Tung, Y., Yen, P.-L., Lin, C.-Y., et al. (2010) · Pharmaceutical Biology · doi:10.3109/13880200903527728 · Cited by 111 · see citing works
Woehrlin, F., Fry, H., Abraham, K., & Preiss-Weigert, A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf102112p · Cited by 110 · see citing works
Cucurbita Plants: From Farm to Industry
Salehi, B., Sharifi‐Rad, J., Çapanoğlu, E., Adrar, N., Çatalkaya, G., Shaheen, S., Jaffer, M., Giri, L., Suyal, R., Jugran, A. K., et al. (2019) · Applied Sciences · doi:10.3390/app9163387 · Cited by 110 · see citing works
Self-citationWu, V. C. H., QIU, X., DELOSREYES, B., et al. (2008) · Food Microbiology · doi:10.1016/j.fm.2008.07.014 · Cited by 108 · see citing works
Zhang, W., Yan-cheng, X. U., Fang-jian, G. U. O., Ye, M., & Li, M. (2008) · Chinese Medical Journal · doi:10.1097/00029330-200811010-00003 · Cited by 107 · see citing works
Bio-Molecular Applications of Recent Developments in Optical Tweezers
Choudhary, D., Mossa, A., Jadhav, M., et al. (2019) · Biomolecules · doi:10.3390/biom9010023 · Cited by 107 · see citing works
Inactivation of Escherichia coli O157:H7 by cinnamic aldehyde purified from Cinnamomum cassia shoot
Kim, H.-O., Park, S.-W., & Park, H.-D. (2003) · Food Microbiology · doi:10.1016/s0740-0020(03)00010-8 · Cited by 106 · see citing works
Inhibition of neuroinflammation by cinnamon and its main components
Ho, S.-C., Chang, K., & Chang, P.-W. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.12.020 · Cited by 106 · see citing works
Jin, X., Wang, L., Liu, S., Zhu, L., Loprinzi, P. D., & Fan, X. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17010031 · Cited by 105 · see citing works
Huang, D., Xu, J., Liu, J. X., Zhang, H., & Hu, Q. P. (2014) · Microbiology · doi:10.1134/s0026261714040067 · Cited by 104 · see citing works
Avocado–Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited
Salehi, B., Rescigno, A., Dettori, T., Călina, D. C., Docea, A. O., Singh, L., Cebeci, F., Özçelik, B., Bhia, M., Beirami, A. D., et al. (2020) · Biomolecules · doi:10.3390/biom10010130 · Cited by 103 · see citing works
Self-citationAntibacterial activity of leaf essential oil and its constituents from Cinnamomum longepaniculatum.
Li, L., Moalin, M., Yin, Z., Qin, W., Jia, R., Zhou, L., Xu, J., Song, X., Zhou, Y., Du, Y.-H., et al. (2014) · Europe PMC (PubMed Central) · Cited by 102 · see citing works
Bioactivity of cinnamon with special emphasis on diabetes mellitus: A review
Bandara, T., Uluwaduge, I., & Jansz, E. R. (2011) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2011.627849 · Cited by 102 · see citing works
Antimicrobial resistance development following surgical site infections
Călina, D. C., Docea, A. O., Roşu, L., et al. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.6034 · Cited by 101 · see citing works
Self-citationJia, Q., Liu, X., Wu, X., Wang, R., Hu, X., Li, Y. H., & Huang, C. (2009) · Phytomedicine · doi:10.1016/j.phymed.2008.12.012 · Cited by 100 · see citing works
Safety issues in using complementary and alternative medicine.
Markman, M. M. (2002) · PubMed · Cited by 99 · see citing works
Arentz, S., Smith, C. A., Abbott, J. A., Fahey, P. P., Cheema, B. S., & Bensoussan, A. (2017) · Phytotherapy Research · doi:10.1002/ptr.5858 · Cited by 98 · see citing works
Rhayour, K., Bouchikhi, T., Tantaoui‐Elaraki, A., Sendide, K., & Remmal, A. (2003) · Journal of Essential Oil Research · doi:10.1080/10412905.2003.9712144 · Cited by 98 · see citing works
Eumkeb, G., Siriwong, S., & Thumanu, K. (2012) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2012.10.006 · Cited by 93 · see citing works
Evaluation of the wound healing activity of an ethanolic extract of Ceylon cinnamon in mice
Farahpour, M. R., & Habibi, M. (2012) · Veterinární Medicína · doi:10.17221/4972-vetmed · Cited by 92 · see citing works
Barceloux, D. G. (2009) · Disease-a-Month · doi:10.1016/j.disamonth.2009.03.003 · Cited by 91 · see citing works
Hepatoprotective activity of cinnamon ethanolic extract against CCI4-induced liver injury in rats.
Eidi, A., Mortazavi, P., Bazargan, M., & Zaringhalam, J. (2012) · PubMed Central · Cited by 91 · see citing works
Veronica Plants—Drifting from Farm to Traditional Healing, Food Application, and Phytopharmacology
Salehi, B., Shetty, M. S., Kumar, N. V. A., Živković, J., Călina, D. C., Docea, A. O., Yazdi, S. E., Kılıç, C. S., Goloshvili, T., Nicola, S., et al. (2019) · Molecules · doi:10.3390/molecules24132454 · Cited by 91 · see citing works
Self-citationAl-Bayati, F. A. Y., & Mohammed, M. J. (2009) · Pharmaceutical Biology · doi:10.1080/13880200802430607 · Cited by 90 · see citing works
Abdelwahab, S. İ., Zaman, F. Q., Mariod, A. A., Yaacob, M., Abdelmageed, A. H. A., & Khamis, S. (2010) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4140 · Cited by 87 · see citing works
Cinnamon-induced stomatitis venenata
Miller, R. L., Gould, A. R., & Bernstein, M. L. (1992) · Oral Surgery Oral Medicine Oral Pathology · doi:10.1016/0030-4220(92)90016-j · Cited by 86 · see citing works
Controlled Trial of the Effect of Cinnamon Extract on Helicobacter pylori
Nir, Y., Potasman, I., Stermer, E., et al. (2000) · Helicobacter · doi:10.1046/j.1523-5378.2000.00014.x · Cited by 85 · see citing works
Shishehbor, F., Safar, M. R., Rajaei, E., et al. (2018) · Journal of the American College of Nutrition · doi:10.1080/07315724.2018.1460733 · Cited by 84 · see citing works
Takasao, N., Tsuji, K., Ishikura, S., Tamura, A., & Akagawa, M. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf2043357 · Cited by 81 · see citing works
Hameed, I. H., Altameme, H. J. M., & Mohammed, G. J. (2016) · Oriental Journal Of Chemistry · doi:10.13005/ojc/320406 · Cited by 81 · see citing works
Antibacterial activities of plant essential oils against Legionella pneumophila
Chang, C., Chang, W.-L., Chang, S., et al. (2007) · Water Research · doi:10.1016/j.watres.2007.07.008 · Cited by 80 · see citing works
Kaul, P. N., Bhattacharya, A. K., Rao, B. R. R., et al. (2002) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.1277 · Cited by 80 · see citing works
The effect of cinnamon cassia powder in type 2 diabetes mellitus.
Suppapitiporn, S., Kanpaksi, N., & Suppapitiporn, S. (2006) · PubMed · Cited by 79 · see citing works
Chen, C., Chen, C., Lo, Y., et al. (2008) · Journal of Natural Products · doi:10.1021/np070620e · Cited by 78 · see citing works
Proanthocyanidins are the major anti-diabetic components of cinnamon water extract
Jiao, L., Zhang, X., Huang, L., Gong, H., Cheng, B., Sun, Y., Li, Y., Liu, Q., Zheng, L., & Huang, K. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.02.049 · Cited by 76 · see citing works
Cytotoxic Compounds from the Stems of Cinnamomum tenuifolium
Lin, R., Cheng, M., Huang, J., Lo, W., Yeh, Y.-T., Yen, C., Lu, C.-M., & Chen, C. (2009) · Journal of Natural Products · doi:10.1021/np900225p · Cited by 75 · see citing works
Mishra, A., Bhatti, R., Singh, A., et al. (2009) · Planta Medica · doi:10.1055/s-0029-1186237 · Cited by 75 · see citing works
Ng, L., & Wu, S.-J. (2009) · Evidence-based Complementary and Alternative Medicine · doi:10.1093/ecam/nep220 · Cited by 74 · see citing works
Chen, L., Sun, P. G., Wang, T., Chen, K., Jia, Q., Wang, H., & Li, Y. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf3024535 · Cited by 73 · see citing works
Cinnamon Spice and Everything Not Nice: Many Features of Intraoral Allergy to Cinnamic Aldehyde
Isaac-Renton, M., Li, M. K., & Parsons, L. M. (2015) · Dermatitis · doi:10.1097/der.0000000000000112 · Cited by 71 · see citing works
Cytotoxic Constituents from the Leaves of Cinnamomum subavenium
Kuo, S., Hsieh, T., Wang, Y., et al. (2008) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.56.97 · Cited by 70 · see citing works
Guerra, F. Q. S., Mendes, J. M., de Sousa, J. P., Morais‐Braga, M. F. B., Santos, B., Coutinho, H. D. M., & Lima, E. D. O. (2011) · Natural Product Research · doi:10.1080/14786419.2011.647019 · Cited by 66 · see citing works
Chen, Y., Ma, Y., & Ma, W. (2009) · European Journal of Drug Metabolism and Pharmacokinetics · doi:10.1007/bf03191384 · Cited by 65 · see citing works
Essential oil composition of Cinnamomum zeylanicum Blume leaves from Little Andaman, India
Raina, V. K., Srivastava, S. K., Aggarwal, K. K., et al. (2001) · Flavour and Fragrance Journal · doi:10.1002/ffj.1016 · Cited by 62 · see citing works
Wu, K., Lin, Y., Chai, X., et al. (2019) · Food Science & Nutrition · doi:10.1002/fsn3.1104 · Cited by 62 · see citing works
Jain, S., Sangma, T., Shukla, S. K., & Mediratta, P. K. (2014) · Nutritional Neuroscience · doi:10.1179/1476830514y.0000000113 · Cited by 61 · see citing works
A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements
Deng, R. (2012) · Recent Patents on Food Nutrition & Agriculture · doi:10.2174/1876142911204010050 · Cited by 61 · see citing works
Vascular Abnormalities and the Role of Vascular Endothelial Growth Factor in the Epileptic Brain
Ogaki, A., Ikegaya, Y., & Koyama, R. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00020 · Cited by 60 · see citing works
Cytotoxic Constituents of the Stems of Cinnamomum subavenium
Chen, C., Chen, C., Wong, C.-H., et al. (2006) · Journal of Natural Products · doi:10.1021/np060425k · Cited by 59 · see citing works
Cytotoxic effect of trans-cinnamaldehyde on human leukemia K562 cells
Zhang, J.-H., Liu, L., He, Y., et al. (2010) · Acta Pharmacologica Sinica · doi:10.1038/aps.2010.76 · Cited by 58 · see citing works
Buru, A. S., Pichika, M. R., Neela, V., & Mohandas, K. (2014) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2014.02.044 · Cited by 57 · see citing works
Tsuji, K. (2008) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2008.09.036 · Cited by 56 · see citing works
Antihyperglycemic and antioxidant activities of twig extract from Cinnamomum osmophloeum
Lin, G., Chen, Y.-H., Yen, P.-L., & Chang, S. (2015) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2015.08.005 · Cited by 55 · see citing works
Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice
Kim, S. H., Hyun, S. H., & Choung, S. (2006) · BioFactors · doi:10.1002/biof.5520260306 · Cited by 55 · see citing works
Molecular and cellular stratagem of brain metastases associated with melanoma (Review)
Bugă, A. M., Docea, A. O., Albu, C. V., Mălin, R. D., Branisteanu, D. E., Ianoși, G., Ianoși, S. L., Iordache, A. M., & Călina, D. C. (2019) · Oncology Letters · doi:10.3892/ol.2019.9933 · Cited by 55 · see citing works
Self-citationIn vitro evaluation of crude extracts of Catharanthus roseus for potential antibacterial activity
Goyal, P., Khanna, A., Chauhan, A., et al. (2008) · International Journal of Green Pharmacy · doi:10.22377/ijgp.v2i3.27 · Cited by 54 · see citing works
Staphylococcus aureus colonisation in patients from a primary regional hospital
Ungureanu, A. M., Zlatian, O. M., Mitroi, G. G., et al. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7746 · Cited by 54 · see citing works
Yun, J.-W., You, J.-R., Kim, Y.-S., Kim, S. H., Cho, E.-Y., Yoon, J.-H., Kwon, E., Jang, J., Park, J., Kim, H.-C., et al. (2018) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2018.02.017 · Cited by 54 · see citing works
Genetic and Epigenetic Characterization of Pulpal and Periapical Inflammation
FOUAD, A. F., khan, A. W. A., Silva, R. M., & Kang, M. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00021 · Cited by 54 · see citing works
Lin, K., YEH, S., Lin, M.-Y., et al. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2007.03.051 · Cited by 53 · see citing works
Panickar, K. S., Polansky, M. M., & Anderson, R. A. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2008.12.024 · Cited by 53 · see citing works
Zlatian, O. M., Bălăşoiu, A. T., Bălăşoiu, M., et al. (2018) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2018.6737 · Cited by 52 · see citing works
Chen, G., Lu, F., Xu, L., Dong, H., Yi, P., Wang, F., Huang, Z., & Zou, X. G. (2013) · Phytomedicine · doi:10.1016/j.phymed.2013.03.004 · Cited by 51 · see citing works
Anderson, D. R., Cordell, H. J., Fakiola, M., Francis, R. W., Syn, G., Scaman, E. S. H., Davis, E. A., Miles, S. J., McLeay, T., Jamieson, S. E., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119333 · Cited by 50 · see citing works
Effects of the polyphenol content on the anti-diabetic activity of Cinnamomum zeylanicum extracts
Krishnakumar, I. M., Issac, A., Johannah, N. M., Ninan, E., Maliakel, B. P., & Kuttan, R. (2014) · Food & Function · doi:10.1039/c4fo00130c · Cited by 49 · see citing works
Analysis of cinnamon oils by high-pressure liquid chromatography
Ross, M. S. F. (1976) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)81222-4 · Cited by 49 · see citing works
Borzoei, A., Rafraf, M., & Jafarabadi, M. A. (2019) · PubMed · doi:10.6133/apjcn.062017.13 · Cited by 49 · see citing works
Occupational allergic contact dermatitis from cinnamon including one case from airborne exposure
Ackermann, L., Aalto‐Korte, K., Jolanki, R., et al. (2009) · Contact Dermatitis · doi:10.1111/j.1600-0536.2008.01486.x · Cited by 44 · see citing works
Safety assessment of standardised methanol extract of Cinnamomum burmannii
Ahmad, M., Lim, C. P., Akowuah, G. A., Ismail, N. N., Hashim, M. A., Hor, S. Y., Ang, L. F., & Yam, M. F. (2013) · Phytomedicine · doi:10.1016/j.phymed.2013.05.005 · Cited by 43 · see citing works
Salmonella enterica adhesion: Effect of Cinnamomum zeylanicum essential oil on lettuce
Rossi, C., Chaves‐López, C., Možina, S. S., Mattia, C. D., Scuota, S., Luzzi, I., Jenič, T., Paparella, A., & Serio, A. (2019) · LWT · doi:10.1016/j.lwt.2019.05.026 · Cited by 43 · see citing works
Cytotoxic Butanolides and Secobutanolides from the Stem Wood of Formosan Lindera communis
Tsai, I., Hung, C.-H., Duh, C., & Chen, I. (2002) · Planta Medica · doi:10.1055/s-2002-20260 · Cited by 42 · see citing works
Neuroprotective Effect of trans-Cinnamaldehyde on the 6-Hydroxydopamine-Induced Dopaminergic Injury
Pyo, J.-H., Jeong, Y.-K., Yeo, S., Lee, J.-H., Jeong, M., Kim, S., Choi, Y., & Lim, S. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b13-00537 · Cited by 42 · see citing works
Cinnamon dermatitis from an ointment
Calnan, C. D. (1976) · Contact Dermatitis · doi:10.1111/j.1600-0536.1976.tb03018.x · Cited by 42 · see citing works
Essential Oils ofCinnamomumSpecies from Peninsular Malaysia
Jantan, I., & Goh, S. H. (1992) · Journal of Essential Oil Research · doi:10.1080/10412905.1992.9698038 · Cited by 41 · see citing works
Kang, B., Racicot, K., Pilkenton, S. J., & Apostolidis, E. (2014) · Plant Foods for Human Nutrition · doi:10.1007/s11130-014-0415-z · Cited by 40 · see citing works
Lipid lowering effect of Cinnamomum zeylanicum in hyperlipidaemic albino rabbits.
Javed, I., Imran, F., Rahman, Z., et al. (2012) · PubMed · Cited by 39 · see citing works
Cinnamon May Reduce Glucose, Lipid and Cholesterol Level in Type 2 Diabetic Individuals
Khan, R., Khan, Z., & Shah, S. H. (2010) · Pakistan Journal of Nutrition · doi:10.3923/pjn.2010.430.433 · Cited by 39 · see citing works
A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements
Deng, R. (2012) · Recent Patents on Food Nutrition & Agriculture · doi:10.2174/2212798411204010050 · Cited by 38 · see citing works
Wiweko, B., & Susanto, C. A. (2017) · PubMed · doi:10.4103/jhrs.jhrs_90_16 · Cited by 38 · see citing works
Al-Logmani, A. S., & Zari, T. A. (2009) · Redalyc (Universidad Autónoma del Estado de México) · Cited by 37 · see citing works
Cinnamon products as a possible etiologic factor in orofacial granulomatosis.
Endo, H., & Rees, T. D. (2007) · PubMed · Cited by 37 · see citing works
Noudeh, G. D., Sharififar, F., Noodeh, A. D., et al. (2010) · Journal of Medicinal Plants Research · doi:10.5897/jmpr10.328 · Cited by 37 · see citing works
Loy, G., Cottiglia, F., Garau, D., et al. (2001) · Il Farmaco · doi:10.1016/s0014-827x(01)01056-4 · Cited by 36 · see citing works
Antihypertensive and Vasorelaxant Effects of Cinnamomum zeylanicum Stem Bark Aqueous Extract in Rats
Nyadjeu, P., Dongmo, A. B., Nguelefack, T. B., et al. (2011) · Journal of Complementary and Integrative Medicine · doi:10.2202/1553-3840.1490 · Cited by 36 · see citing works
Leela, N. K. (2008) · CABI eBooks · doi:10.1079/9781845934057.0124 · Cited by 35 · see citing works
In vitro evaluation of crude extracts of Catharanthus roseus for potential antibacterial activity
Goyal, P., Khanna, A., Chauhan, A., et al. (2008) · International Journal of Green Pharmacy · doi:10.4103/0973-8258.42739 · Cited by 33 · see citing works
Effects of Piperine, Cinnamic Acid and Gallic Acid on Rosuvastatin Pharmacokinetics in Rats
Basu, S., Jana, S., Patel, V. B., & Patel, H. (2012) · Phytotherapy Research · doi:10.1002/ptr.4894 · Cited by 32 · see citing works
Rameshkumar, K. B., George, V., & Sugathan, S. (2007) · Journal of Essential Oil Research · doi:10.1080/10412905.2007.9699238 · Cited by 32 · see citing works
Panickar, K. S., Polansky, M. M., Graves, D. J., Urban, J. F., & Anderson, R. A. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.11.051 · Cited by 31 · see citing works
Control of planktonic and sessile bacterial cells by essential oils
de Oliveira, M. M. M., Brugnera, D. F., do Nascimento, J. A., et al. (2012) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2012.03.002 · Cited by 31 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- EUROPEAN SCIENTIFIC COOPERATIVE ON PHYTOTHERAPY (2003). ESCOP Monographs. 2nd ed. Amsterdam, Netherlands: World Press.
- Liao J. C. Deng J. S. Chiu C. S. Hou W. C. Huang S. S. Shie P. H. (2012b). Anti-Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo. Evid. Based Complement. Alternat Med. 2012, 429320. 10.1155/2012/429320 22536283 PMC3318905 · DOI
- ORGANIZATION (2001). Joint FAO/WHO Expert Committee on Food Additives. Safety evaluation of certain food additives and contaminants in food: Fumonisins. Proceedings of the 56th Meeting of the Joint FAO/WHO Expert Committee on Food Additives, 103– 279.
- Ravindran P. Nirmal-Babu K. Shylaja M. (2003). Cinnamon and cassia: The Genus Cinnamomum. CRC Press.
Cited by
Sorted by citations
Dhyani, P., Quispe, C., Sharma, E., Bahukhandi, A., Sati, P., Attri, D. C., Szopa, A., Sharifi-Rad, J., Docea, A. O., Mardare, I., et al. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02624-9 · Cited by 483 · see citing works
Self-citationSharifi-Rad, J., Quispe, C., Imran, M., Rauf, A., Nadeem, M., Gondal, T. A., Ahmad, B., Atif, M., Mubarak, M. S., Sytar, O., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/3268136 · Cited by 389 · see citing works
Self-citationNeuropharmacological Effects of Quercetin: A Literature-Based Review
Islam, M. S., Quispe, C., Hossain, R., Islam, M. T., Al-Harrasi, A., Al-Rawahi, A., Martorell, M., Mamurova, A., Seilkhan, A., Altybaeva, N., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.665031 · Cited by 165 · see citing works
Self-citationSharifi-Rad, J., Rapposelli, S., Sestito, S., Herrera-Bravo, J., Arancibia-Diaz, A., Salazar, L. A., Yeskaliyeva, B., Beyatli, A., Leyva-Gómez, G., González-Contreras, C., et al. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12091515 · Cited by 125 · see citing works
Self-citationMyricetin: Targeting signaling networks in cancer and its implication in chemotherapy
Javed, Z., Khan, K., Herrera-Bravo, J., Naeem, S., Iqbal, M. J., Raza, Q., Sadia, H., Raza, S., Bhinder, M., Calina, D., et al. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02663-2 · Cited by 93 · see citing works
Self-citationTherapeutic Applications of Curcumin in Diabetes: A Review and Perspective
Quispe, C., Herrera-Bravo, J., Javed, Z., Khan, K., Raza, S., Gulsunoglu-Konuskan, Z., Daştan, S. D., Sytar, O., Martorell, M., Sharifi-Rad, J., et al. (2022) · BioMed Research International · doi:10.1155/2022/1375892 · Cited by 92 · see citing works
Self-citationA Pharmacological Perspective on Plant-derived Bioactive Molecules for Epilepsy
Sharifi-Rad, J., Quispe, C., Herrera-Bravo, J., Martorell, M., Sharopov, F., Tumer, T. B., Kurt, B., Lankatillake, C., Docea, A. O., Moreira, A. C., et al. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03376-0 · Cited by 60 · see citing works
Self-citationReversal of brain aging by targeting telomerase: A nutraceutical approach
Tsoukalas, D., Buga, A., Docea, A., Sarandi, E., Mitrut, R., Renieri, E., Spandidos, D., Rogoveanu, I., Cercelaru, L., Niculescu, M., et al. (2021) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2021.5032 · Cited by 40 · see citing works
Self-citation
- Authors
- Sharifi-Rad, J., Dey, A., Koirala, N., Shaheen, S., El Omari, N., Salehi, B., Goloshvili, T., Cirone Silva, N. C., Bouyahya, A., Vitalini, S., Varoni, E. M., Martorell, M., Abdolshahi, A., Docea, A. O., Iriti, M., Calina, D., Les, F., López, V., & Caruntu, C.
- Affiliations
- Presidency University (IN)
- Lahore College for Women University (PK)
- Shahid Beheshti University (IR)
- Ilia State University (GE)
- Mohammed V University (MA)
- University of Milan (IT)
- University of Concepción (CL)
- Semnan University of Medical Sciences (IR)
- University of Medicine and Pharmacy of Craiova (RO)
- Universidad de Zaragoza (ES)
- Corresponding author
- Salehi, Bahare
- Bouyahya, Abdelhakim
- Martorell, Miquel
- Les, Francisco
- ORCID
- Venue
- Frontiers in Pharmacology
- Publisher
- Frontiers Media SA
- Published
- 2021-05-11
- Volume
- 12
- Pages
- 600139-600139
- ISSN
- 1663-9812 (ISSN-L)
- PMC
- PMC8144503
- OpenAlex
- W3161674658
- Cited by
- 183
- References
- 236
- Citations by year
- 2026: 25 · 2025: 37 · 2024: 30 · 2023: 45 · 2022: 36 · 2021: 10
- FWCI
- 2.90
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Pharmacology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Zaguan (University of Zaragoza Repository) (publishedVersion, other-oa)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Greater South Information System
- Funders
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii
- Comisión Nacional de Investigación Científica y Tecnológica (CCTE AFB170007, AFB170007)
- Colegiul Consultativ pentru Cercetare-Dezvoltare şi Inovare
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Piperaceae Chemical and Biological Studies
- Keywords
- Cinnamomum, cinnamon, bioactive compounds, phytochemistry, pharmacological activity, toxicological safety, antimicrobial activity, antidiabetic activity, antioxidant activity, anti-inflammatory activity, anticancer activity, neuroprotection, molecular mechanisms, herbal medicine, spices, drug development
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review