The DOI matches its Crossref record; 60 of the 62 references it cites were found in a registry or an index.
Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the ‘‘right stuff’’?
Abstract
There has been a surge of interest in the functional consequences of neurocognitive deficits in schizophrenia. The published literature in this area has doubled in the last few years. In this paper, we will attempt to confirm the conclusions from a previous review that certain neurocognitive domains (secondary verbal memory, immediate memory, executive functioning as measured by card sorting, and vigilance) are associated with functional outcome. In addition to surveying the number of replicated findings and tallying box scores of results, we will approach the review of the studies in a more thorough and empirical manner by applying a meta-analysis. Lastly, we will discuss what we see as a key limitation of this literature, specifically, the relatively narrow selection of predictor measures. This limitation has constrained identification of mediating variables that may explain the mechanisms for these relationships.
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“Cognition determines, to a considerable extent, one's social and professional success and the ability to live independently (Audet, Hebert, Dubois, Rochette, & Mercier, 2007; Benedict & Zivadinov, 2006; Green, Kern, Braff, & Mintz, 2000).”
From Efficacy of non-invasive brain stimulation on cognitive functioning in brain disorders: a meta-analysis (2020) · cites this paper as Green, Kern, Braff, & Mintz, 2000
In the citing paper
“These impairments have been shown to be associated with various impaired functional outcomes.4,5”
From Clinical trials of potential cognitive-enhancing drugs in schizophrenia: what have we learned so far? (2013) · cites this paper as [4]
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Cites
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What are the functional consequences of neurocognitive deficits in schizophrenia?
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Self-citationVygotsky and the Social Formation of Mind
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Further Evidence for Dementia of the Prefrontal Type in Schizophrenia?
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Should schizophrenia be treated as a neurocognitive disorder?
Green, M. F., & Nuechterlein, K. (1999) · Schizophrenia bulletin · doi:10.1093/oxfordjournals.schbul.a033380 · Cited by 447
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Items 1,001–1,017 of 1,017
Bralet, M., Falissard, B., Neveu, X., Lucas-Ross, M., Eskenazi, A.-M., & Keefe, R. S. E. (2007) · European Psychiatry · doi:10.1016/j.eurpsy.2007.02.001 · Cited by 39
Poor functioning ability is associated with high risk of developing psychosis in adolescents
Granö, N., Karjalainen, M., Suominen, K. H., & Roine, M. (2010) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2010.483743 · Cited by 39
Reversal of Ketamine-Induced Working Memory Impairments by the GABAAα2/3 Agonist TPA023
Castner, S. A., Arriza, J. L., Roberts, J. C., Mrzljak, L., Christian, E. P., & Williams, G. V. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.01.001 · Cited by 37
Targeting sleep oscillations to improve memory in schizophrenia
Manoach, D. S., Mylonas, D., & Baxter, B. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.01.010 · Cited by 36
Neuro-Cognition and Social Cognition Elements of Social Functioning and Social Quality of Life
Hasson-Ohayon, I., Mashiach-Eizenberg, M., Arnon-Ribenfeld, N., Kravetz, S., & Roe, D. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.09.004 · Cited by 34
Edmonds, E. C., Martin, A. S., Palmer, B. W., Eyler, L. T., Rana, B. K., & Jeste, D. V. (2018) · Aging & Mental Health · doi:10.1080/13607863.2016.1251572 · Cited by 27
Eklund, M. (2007) · American Journal of Occupational Therapy · doi:10.5014/ajot.61.5.535 · Cited by 25
Ahmed, A. O., Murphy, C. F., Latoussakis, V., McGovern, K. E., English, J., Bloch, A., Anthony, D. T., & Savitz, A. J. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.01.001 · Cited by 22
Correlation between age and MMSE in schizophrenia
Maltais, J.-R., Gagnon, G., Garant, M.-P., & Trudel, J.-F. (2015) · International Psychogeriatrics · doi:10.1017/s1041610215000459 · Cited by 20
Stability and functional correlates of memory-based classification in older schizophrenia patients
Bowie, C. R., Reichenberg, A., Rieckmann, N., Parrella, M., White, L., & Harvey, P. D. (2004) · The American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200407000-00005 · Cited by 20
Martinez Agulleiro, L., Patil, B., Firth, J., Sawyer, C., Amann, B. L., Fonseca, F., Torrens, M., Perez, V., Castellanos, F. X., Kane, J. M., et al. (2023) · Psychological Medicine · doi:10.1017/s003329172300123x · Cited by 19
Turner, K. M., & Burne, T. H. J. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00097 · Cited by 16
“Cognitive deficits are a core symptom group associated with schizophrenia and are the strongest predictor of functional patient outcomes (Green et al., 2000).”
BackgroundRomero-Ayuso, D., Jorquera-Cabrera, S., Segura-Fragoso, A., Toledano-González, A., Rodríguez-Martínez, M. C., & Triviño-Juárez, J. M. (2018) · Frontiers in Pediatrics · doi:10.3389/fped.2018.00071 · Cited by 15
“It is, therefore, understood that a deficit of executive functions can have devastating effects on activities of daily life that could be interpreted as human occupations in a broad sense, such as school activities, self-care, play, leisure, and social participation (11, 16, 17).”
BackgroundDing, Y., Hou, W., Wang, C., Sha, S., Dong, F., Li, X., Wang, N., Lam, S. T., Zhou, F., & Wang, C. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.06.048 · Cited by 9
Larsson, C., Fatouros-Bergman, H., Isaksson, A., Johansson, M., Kaldo, V., Parling, T., & Lundgren, T. (2022) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2022.05.008 · Cited by 5
Hoshino, A., Asakura, T., Cho, K., Murata, N., Kogata, T., Kawamura, M., Kito, A., & Kato, U. (2020) · British Journal of Occupational Therapy · doi:10.1177/0308022620922420 · Cited by 1
Hache-Labelle, C., Simard, S., Villeneuve, M., Abdel-Baki, A., Lepage, M., Archibaldo Bravo, M., & Lecomte, T. (2023) · Journal of Behavioral and Cognitive Therapy · doi:10.1016/j.jbct.2023.10.003 · Cited by 1
Metadata
- Authors
- Green, M. F., Kern, R. S., Braff, D. L., & Mintz, J.
- Affiliations
- University of California, Los Angeles (US)
- University of California San Diego (US)
- Corresponding author
- Green, M. F.
- ORCID
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-01-01
- Volume
- 26
- Issue
- 1
- Pages
- 119-136
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- OpenAlex
- W2150174494
- Cited by
- 2,999
- References
- 62
- Citations by year
- 2026: 49 · 2025: 50 · 2024: 85 · 2023: 77 · 2022: 89 · 2021: 111 · 2020: 120 · 2019: 146 · 2018: 132 · 2017: 143 · 2016: 146 · 2015: 180 · 2014: 146 · 2013: 180 · 2012: 183
- FWCI
- 31.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Bulletin (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- schizophrenia, neurocognitive impairment
- MeSH terms
- Cognition Disorders, Humans, Neuropsychological Tests, Schizophrenia, Schizophrenic Psychology, Social Adjustment, Comorbidity, Cognitive Behavioral Therapy, Treatment Outcome
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