Cited by 218Schizophrenia research and treatmentMental Health and PsychiatryPsychotherapy Techniques and Applications

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Acceptance and Efficacy of Metacognitive Training (MCT) on Positive Symptoms and Delusions in Patients With Schizophrenia: A Meta-analysis Taking Into Account Important Moderators

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Eichner, Carolin, Berna, Fabrice·2016·Schizophrenia Bulletin

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Abstract

Metacognitive training (MCT) is a new, widely used intervention for psychosis. The present meta-analysis examines the efficacy of MCT in schizophrenia. Fifteen studies comparing effects of MCT on positive symptoms, delusions or acceptance of MCT with a control group were included in this meta-analysis. These studies comprised a total of 408 patients in the MCT condition and 399 in the control condition. The moderating effects of masking of outcome assessment, randomization, incomplete outcome data, use of an active control intervention, and individual vs group MCT were investigated. Possible effects of sensitivity analyses and publication bias were also examined. The results show a significant overall effect of MCT for positive symptoms (g = -0.34, 95% CI [-0.53, -0.15]), delusions (g = -0.41, 95% CI [-0.74, -0.07]) and acceptance of the intervention (g = -0.84, 95% CI [-1.37, -0.31]). Using only studies being at low risk for bias regarding randomization, masking and incomplete outcome data reduced effect sizes for positive symptoms and delusions (g = -0.28, 95% CI [-0.50, -0.06] and g = -0.18, 95% CI [-0.43, 0.06]), respectively. This meta-analysis demonstrates that MCT exerts a small to moderate effect on delusions and positive symptoms and a large effect on acceptance of the intervention. The effect on delusions is reduced, but remains significant when potential biases are considered.

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Authors: Eichner, C., & Berna, F.
Affiliations: Universität Hamburg (DE)
Corresponding author: Berna, Fabrice
ORCID: Berna, Fabrice
Venue: Schizophrenia Bulletin
Publisher: Oxford University Press (OUP)
Published: 2016-01-08
Volume: 42
Issue: 4
Pages: 952-962
ISSN: 0586-7614 (ISSN-L)
1745-1701
DOI: 10.1093/schbul/sbv225
PMC: PMC4903058
OpenAlex: W2226563784
Cited by: 218
References: 62
Citations by year: 2026: 2 · 2025: 10 · 2024: 8 · 2023: 11 · 2022: 63 · 2021: 19 · 2020: 29 · 2019: 18 · 2018: 25 · 2017: 18 · 2016: 13
FWCI: 3.53
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Schizophrenia Bulletin (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
HighWire Press Open Archive (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: metacognitive training, schizophrenia
MeSH terms: Metacognition, Cognitive Remediation, Delusions, Humans, Patient Acceptance of Health Care, Psychotic Disorders, Schizophrenia, Effect Modifier, Epidemiologic, Outcome Assessment, Health Care

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Acceptance and Efficacy of Metacognitive Training (MCT) on Positive Symptoms and Delusions in Patients With Schizophrenia: A Meta-analysis Taking Into Account Important Moderators

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