CoChat
Sign Up
Cited by 9

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Paradoxical effects from stimulus density manipulation provide new insight into the impact of sleep deprivation on PVT performance

Honn, Kimberly A, Van Dongen, Hans P A·2023·SLEEP Advances
DOI 10.1093/sleepadvances/zpac045PMC PMC10108643
Open this paper in CoChat — free account

Abstract

Study Objectives: The psychomotor vigilance test (PVT), a 10-min one-choice reaction time task with random response-stimulus intervals (RSIs) between 2 and 10 s, is highly sensitive to behavioral alertness deficits due to sleep loss. To investigate what drives the performance deficits, we conducted an in-laboratory total sleep deprivation (TSD) study and compared performance on the PVT to performance on a 10-min high-density PVT (HD-PVT) with increased stimulus density and truncated RSI range between 2 and 5 s. We hypothesized that the HD-PVT would show greater impairments from TSD than the standard PVT. Methods: n = 86 healthy adults were randomized (2:1 ratio) to 38 h of TSD (n = 56) or corresponding well-rested control (n = 30). The HD-PVT was administered when subjects had been awake for 34 h (TSD group) or 10 h (control group). Performance on the HD-PVT was compared to performance on the standard PVTs administered 1 h earlier and 1 h later. Results: The HD-PVT yielded approximately 60% more trials than the standard PVT. The HD-PVT had faster mean response times (RTs) and equivalent lapses (RTs > 500 ms) compared to the standard PVT, with no differences between the TSD effects on mean RT and lapses between tasks. Further, the HD-PVT had a dampened time-on-task effect in both the TSD and control conditions. Conclusions: Contrary to expectation, the HD-PVT did not show greater performance impairment during TSD, indicating that stimulus density and RSI range are not primary drivers of the PVT’s responsiveness to sleep loss.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/sleepadvances/zpac045

Cites

7 of 7 references verified0 citation errors · 0 not checkable

Statistics

Figures

Figure 1. Signature effects captured by the PVT. (A) Performance degrades with increasing time on task, which is exacerbated by sleep loss. A 10-min standard PVT was administered every 3 h throughout 38 h of total sleep deprivation (TSD), which lasted from 08:00 until 22:00 the following evening. Mean RT (± SE) from 16 healthy adults is plotted per 1-min interval across the 10-min task duration, showing progressive slowing within each test bout, especially in the later part of the TSD period. Note that placement of the 1-min bins in each test is not to scale on the hours awake axis. Adapted from Fig. 2 in Grant et al. [12]. (B) Performance is worse for shorter response-stimulus intervals (RSIs), which is exacerbated by sleep loss. The percentage of RTs classified as lapses (RT > 500 ms) from 54 healthy adults who completed a 10-min PVT at 10:00 after 3.5 h awake and 24 h later after 27.5 h awake is plotted as a function of RSI sub-groups (with continuous-range RSIs between 2 and 10 s divided into 7 equal intervals on a log scale). Curves redrawn from data provided as part of Fig. 3 in Yang et al. [55]. (C) Extended wakefulness causes a rightward skewing of the RT distribution. The distribution of raw RTs from 9 healthy adults performing the PVT at 01:30 after 16 hours of wakefulness and after 40 hours of wakefulness is plotted. Adapted from Fig. 4.1 in Dinges and Kribbs [2]. (D) Sleep deprivation produces “lapses” evident as the emergence of slow RTs interspersed among fast RTs. Individual RTs for a healthy adult performing a PVT at 20:00 after 12 h awake (top panel) and again after 60 h awake (bottom panel). Gaps indicate false starts, the prevalence of which increases after sleep deprivation as well. Adapted from Fig. 3 in Doran et al. [3].
Figure 1. Signature effects captured by the PVT. (A) Performance degrades with increasing time on task, which is exacerbated by sleep loss. A 10-min standard PVT was administered every 3 h throughout 38 h of total sleep deprivation (TSD), which lasted from 08:00 until 22:00 the following evening. Mean RT (± SE) from 16 healthy adults is plotted per 1-min interval across the 10-min task duration, showing progressive slowing within each test bout, especially in the later part of the TSD period. Note that placement of the 1-min bins in each test is not to scale on the hours awake axis. Adapted from Fig. 2 in Grant et al. [12]. (B) Performance is worse for shorter response-stimulus intervals (RSIs), which is exacerbated by sleep loss. The percentage of RTs classified as lapses (RT > 500 ms) from 54 healthy adults who completed a 10-min PVT at 10:00 after 3.5 h awake and 24 h later after 27.5 h awake is plotted as a function of RSI sub-groups (with continuous-range RSIs between 2 and 10 s divided into 7 equal intervals on a log scale). Curves redrawn from data provided as part of Fig. 3 in Yang et al. [55]. (C) Extended wakefulness causes a rightward skewing of the RT distribution. The distribution of raw RTs from 9 healthy adults performing the PVT at 01:30 after 16 hours of wakefulness and after 40 hours of wakefulness is plotted. Adapted from Fig. 4.1 in Dinges and Kribbs [2]. (D) Sleep deprivation produces “lapses” evident as the emergence of slow RTs interspersed among fast RTs. Individual RTs for a healthy adult performing a PVT at 20:00 after 12 h awake (top panel) and again after 60 h awake (bottom panel). Gaps indicate false starts, the prevalence of which increases after sleep deprivation as well. Adapted from Fig. 3 in Doran et al. [3].CC BY-NC-ND · PubMed Central
Figure 2. Testing timeline, task specifications, and descriptive statistics.
Figure 2. Testing timeline, task specifications, and descriptive statistics.CC BY-NC-ND · PubMed Central
Figure 3. (A) Mean RT, (B) number of lapses, (C) percent of lapses, and (D) false starts. Data shown are mean ± SE on the standard PVT (open circles) and the HD-PVT (closed circles), by condition, as a function of measurement time. Data from control subjects are shown in blue and from TSD subjects in red.
Figure 3. (A) Mean RT, (B) number of lapses, (C) percent of lapses, and (D) false starts. Data shown are mean ± SE on the standard PVT (open circles) and the HD-PVT (closed circles), by condition, as a function of measurement time. Data from control subjects are shown in blue and from TSD subjects in red.CC BY-NC-ND · PubMed Central
Figure 4. Time-on-task effect displayed as mean RT per 1-min bin on the standard PVT and the HD-PVT. Data shown are mean ± SE by condition as a function of measurement time.
Figure 4. Time-on-task effect displayed as mean RT per 1-min bin on the standard PVT and the HD-PVT. Data shown are mean ± SE by condition as a function of measurement time.CC BY-NC-ND · PubMed Central
Figure 5. Response-stimulus interval (RSI) effect displayed as mean RT for each RSI on the standard PVT and the HD-PVT. Data shown are mean ± SE per RSI duration in the TSD condition (left) and the control condition (right) on the standard PVT at 17:00 (open circles), the HD-PVT at 18:00 (filled circles), and the standard PVT at 19:00 (open triangles). Note that although the figure shows all RSIs for each test (i.e. 2–10 s for the standard PVT and 2–5 s for the HD-PVT), the analyses of the RSI effect included only RSIs common between the two task versions, as indicated by the gray rectangles (i.e. 2–5 s).
Figure 5. Response-stimulus interval (RSI) effect displayed as mean RT for each RSI on the standard PVT and the HD-PVT. Data shown are mean ± SE per RSI duration in the TSD condition (left) and the control condition (right) on the standard PVT at 17:00 (open circles), the HD-PVT at 18:00 (filled circles), and the standard PVT at 19:00 (open triangles). Note that although the figure shows all RSIs for each test (i.e. 2–10 s for the standard PVT and 2–5 s for the HD-PVT), the analyses of the RSI effect included only RSIs common between the two task versions, as indicated by the gray rectangles (i.e. 2–5 s).CC BY-NC-ND · PubMed Central
Figure 6. Illustration of the one-choice diffusion decision model for the PVT. After presentation of a stimulus and subsequent stimulus encoding, a decision process takes place during which evidence is accumulated through neuronal processing resembling a random walk with a certain drift rate. When the accumulated evidence reaches an evidence criterion, the decision process stops and a response is made. While performing the PVT, the evidence criterion must be set in advance of the stimulus onset and maintained throughout the RSI, which in the face of sleep deprivation may require sustained effort. Figure adapted from Ratcliff and Van Dongen [75].
Figure 6. Illustration of the one-choice diffusion decision model for the PVT. After presentation of a stimulus and subsequent stimulus encoding, a decision process takes place during which evidence is accumulated through neuronal processing resembling a random walk with a certain drift rate. When the accumulated evidence reaches an evidence criterion, the decision process stops and a response is made. While performing the PVT, the evidence criterion must be set in advance of the stimulus onset and maintained throughout the RSI, which in the face of sleep deprivation may require sustained effort. Figure adapted from Ratcliff and Van Dongen [75].CC BY-NC-ND · PubMed Central

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 7 references

Research works printed but not linked: 78

  1. Dinges, 1985, Microcomputer analyses of performance on a portable, simple visual RT task during sustained operations, Behav Res Methods Instrum Comput., 17, 652, 10.3758/BF03200977 · DOI
  2. Dinges, 1991, Performing while sleepy: effects of experimentally-induced sleepiness., 97
  3. Doran, 2001, Sustained attention performance during sleep deprivation: evidence of state instability, Arch Ital Biol., 139, 253
  4. Dorrian, 2005, Psychomotor vigilance performance: neurocognitive assay sensitive to sleep loss., 39
  5. Hudson, 2020, Sleep deprivation, vigilant attention, and brain function: a review, Neuropsychopharmacology., 45, 21, 10.1038/s41386-019-0432-6 · DOI · Paper page
  6. Satterfield, 2013, Occupational fatigue, underlying sleep and circadian mechanisms, and approaches to fatigue risk management, Fatigue., 1, 118
  7. Thorne, 2005, The Walter Reed palm-held psychomotor vigilance test, Behav Res Methods., 37, 111, 10.3758/BF03206404 · DOI · Paper page
  8. Lamond, 2008, The sensitivity of a palm-based psychomotor vigilance task to severe sleep loss, Behav Res Methods., 40, 347, 10.3758/BRM.40.1.347 · DOI
  9. Basner, 2011, Validity and sensitivity of a brief Psychomotor Vigilance Test (PVT-B) to total and partial sleep deprivation, Acta Astronaut., 69, 949, 10.1016/j.actaastro.2011.07.015 · DOI · Paper page
  10. Honn, 2015, Validation of a portable, touch-screen psychomotor vigilance test, Aerosp Med Hum Perform., 86, 428, 10.3357/AMHP.4165.2015 · DOI
  11. Grant, 2017, 3-minute smartphone-based and tablet-based psychomotor vigilance tests for the assessment of reduced alertness due to sleep deprivation, Behav Res Methods., 49, 1020, 10.3758/s13428-016-0763-8 · DOI
  12. Arsintescu, 2019, Validation of a touchscreen psychomotor vigilance task, Accid Anal Prev., 126, 173, 10.1016/j.aap.2017.11.041 · DOI
  13. Benderoth, 2021, Reliability and validity of a 3-min psychomotor vigilance task in assessing sensitivity to sleep loss and alcohol: fitness for duty in aviation and transportation, Sleep., 44, zsab151, 10.1093/sleep/zsab151 · DOI
  14. Thompson, 2022, Test-retest reliability of the 5-minute psychomotor vigilance task in working-aged females, J Neurosci Methods., 365, 109379, 10.1016/j.jneumeth.2021.109379 · DOI
  15. Jung, 2011, Comparison of sustained attention assessed by auditory and visual psychomotor vigilance tasks prior to and during sleep deprivation, J Sleep Res., 20, 348, 10.1111/j.1365-2869.2010.00877.x · DOI
  16. Balkin, 2004, Comparative utility of instruments for monitoring sleepiness-related performance decrements in the operational environment, J Sleep Res., 13, 219, 10.1111/j.1365-2869.2004.00407.x · DOI · Paper page
  17. Basner, 2011, Maximizing sensitivity of the psychomotor vigilance test (PVT) to sleep loss, Sleep., 34, 581, 10.1093/sleep/34.5.581 · DOI · Paper page
  18. Banks, 2007, Behavioral and physiological consequences of sleep restriction, J Clin Sleep Med., 3, 519, 10.5664/jcsm.26918 · DOI · Paper page
  19. Ganesan, 2019, The impact of shift work on sleep, alertness and performance in healthcare workers, Sci Rep., 9, 4635, 10.1038/s41598-019-40914-x · DOI · Paper page
  20. Hilditch, 2016, Sleep inertia during a simulated 6-h on/6-h off fixed split duty schedule, Chronobiol Int., 33, 685, 10.3109/07420528.2016.1167724 · DOI
  21. Kribbs, 1993, Effects of one night without nasal CPAP treatment on sleep and sleepiness in patients with obstructive sleep apnea, Am Rev Respir Dis., 147, 1162, 10.1164/ajrccm/147.5.1162 · DOI
  22. Thomann, 2014, Psychomotor vigilance task demonstrates impaired vigilance in disorders with excessive daytime sleepiness, J Clin Sleep Med., 10, 1019, 10.5664/jcsm.4042 · DOI
  23. Khan, 2019, Immediate-term cognitive impairment following intravenous (IV) chemotherapy: a prospective pre-post design study, BMC Cancer., 19, 150, 10.1186/s12885-019-5349-2 · DOI
  24. Wilson, 2019, Postpartum fatigue, daytime sleepiness, and psychomotor vigilance are modifiable through a brief residential early parenting program, Sleep Med., 59, 33, 10.1016/j.sleep.2019.01.012 · DOI
  25. Reiter, 2021, No effect of chronotype on sleepiness, alertness, and sustained attention during a single night shift, Clocks Sleep., 3, 377, 10.3390/clockssleep3030024 · DOI
  26. Van Dongen, 2003, The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation, Sleep., 26, 117, 10.1093/sleep/26.2.117 · DOI · Paper page
  27. Basner, 2018, Repeated administration effects on psychomotor vigilance test performance, Sleep., 41, zsx187, 10.1093/sleep/zsx187 · DOI
  28. Belenky, 2003, Patterns of performance degradation and restoration during sleep restriction and subsequent recovery: a sleep dose-response study, J Sleep Res., 12, 1, 10.1046/j.1365-2869.2003.00337.x · DOI · Paper page
  29. Mollicone, 2008, Response surface mapping of neurobehavioral performance: testing the feasibility of split sleep schedules for space operations, Acta Astronaut., 63, 833, 10.1016/j.actaastro.2007.12.005 · DOI
  30. Signal, 2009, Scheduled napping as a countermeasure to sleepiness in air traffic controllers, J Sleep Res., 18, 11, 10.1111/j.1365-2869.2008.00702.x · DOI
  31. Banks, 2010, Neurobehavioral dynamics following chronic sleep restriction: dose-response effects of one night for recovery, Sleep., 33, 1013, 10.1093/sleep/33.8.1013 · DOI · Paper page
  32. Rupp, 2009, Banking sleep: realization of benefits during subsequent sleep restriction and recovery, Sleep., 32, 311, 10.1093/sleep/32.3.311 · DOI · Paper page
  33. Graw, 2004, Circadian and wake-dependent modulation of fastest and slowest reaction times during the psychomotor vigilance task, Physiol Behav., 80, 695, 10.1016/j.physbeh.2003.12.004 · DOI
  34. Dinges, 2003, Effects of modafinil on sustained attention performance and quality of life in OSA patients with residual sleepiness while being treated with nCPAP, Sleep Med., 4, 393, 10.1016/S1389-9457(03)00108-4 · DOI · Paper page
  35. Wesensten, 2004, Modafinil vs. caffeine: effects on fatigue during sleep deprivation, Aviat Space Environ Med., 75, 520
  36. Van Dongen, 2004, Systematic interindividual differences in neurobehavioral impairment from sleep loss: evidence of trait-like differential vulnerability, Sleep., 27, 423
  37. Ferguson, 2016, Fatigue in emergency service operations: assessment of the optimal objective and subjective measures using a simulated wildfire deployment, Int J Environ Res Public Health., 13, 171, 10.3390/ijerph13020171 · DOI
  38. Sparrow, 2016, Naturalistic field study of the restart break in US commercial motor vehicle drivers: Truck driving, sleep, and fatigue, Accid Anal Prev., 93, 55, 10.1016/j.aap.2016.04.019 · DOI
  39. Patterson, 2019, Impact of shift duration on alertness among air-medical emergency care clinician shift workers, Am J Ind Med., 62, 325, 10.1002/ajim.22956 · DOI
  40. Wilson, 2019, Performance and sleepiness in nurses working 12-h day shifts or night shifts in a community hospital, Accid Anal Prev., 126, 43, 10.1016/j.aap.2017.09.023 · DOI
  41. Matsangas, 2020, Sleep quality, occupational factors, and psychomotor vigilance performance in the U.S. Navy sailors, Sleep., 43, zsaa118, 10.1093/sleep/zsaa118 · DOI
  42. Rahman, 2021, Extended work shifts and neurobehavioral performance in resident-physicians, Pediatrics., 147, e2020009936, 10.1542/peds.2020-009936 · DOI
  43. Fletcher, 2022, Work schedule and seasonal influence on sleep and fatigue in helicopter and fixed-wing aircraft operations in extreme environments, Sci Rep., 12, 8263, 10.1038/s41598-022-08996-2 · DOI
  44. Mackworth, 1950, Researches on the measurement of human performance, 156
  45. Broadbent, 1953, Noise, paced performance and vigilance tasks, Br J Psychol., 44, 295
  46. Bills, 1937, Fatigue in mental work, Physiol Rev., 17, 436, 10.1152/physrev.1937.17.3.436 · DOI
  47. Van Dongen, 2011, Investigating the temporal dynamics and underlying mechanisms of cognitive fatigue., 127, 10.1037/12343-006 · DOI
  48. Tucker, 2009, The variable response-stimulus interval effect and sleep deprivation: an unexplored aspect of psychomotor vigilance task performance, Sleep., 32, 1393, 10.1093/sleep/32.10.1393 · DOI
  49. Kong, 2015, Increased automaticity and altered temporal preparation following sleep deprivation, Sleep., 38, 1219, 10.5665/sleep.4896 · DOI
  50. Yang, 2018, Sleep deprivation enhances inter-stimulus interval effect on vigilant attention performance, Sleep., 41, zsy189, 10.1093/sleep/zsy189 · DOI
  51. Luce, 1991, Response Times: Their Role in Inferring Elementary Mental organization., 10.1093/acprof:oso/9780195070019.001.0001 · DOI
  52. Bills, 1931, Blocking: a new principle in mental fatigue, Am J Psychol., 43, 230, 10.2307/1414771 · DOI
  53. Williams, 1959, Impaired performance with acute sleep loss, Psychol Monogr., 73, 1, 10.1037/h0093749 · DOI
  54. Deaton, 1971, The effect of sleep deprivation on signal detection parameters, Q J Exp Psychol., 23, 449, 10.1080/14640747108400257 · DOI
  55. Gunzelmann, 2011, Fatigue in sustained attention: Generalizing mechanisms for time awake to time on task., 83, 10.1037/12343-004 · DOI
  56. Basner, 2015, A new likelihood ratio metric for the psychomotor vigilance test and its sensitivity to sleep loss, J Sleep Res., 24, 702, 10.1111/jsr.12322 · DOI
  57. Chavali, 2017, Signal-to-noise ratio in PVT performance as a cognitive measure of the effect of sleep deprivation on the fidelity of information processing, Sleep., 40, zsx016, 10.1093/sleep/zsx016 · DOI
  58. Horne, 1985, High incentive effects on vigilance performance during 72 hours of total sleep deprivation, Acta Psychol (Amst)., 58, 123, 10.1016/0001-6918(85)90003-4 · DOI
  59. Rakitin, 2012, The effects of stimulus degradation after 48 hours of total sleep deprivation, Sleep., 35, 113, 10.5665/sleep.1598 · DOI
  60. Dinges, 1989, The nature of sleepiness: causes, contexts, and consequences., 147
  61. Van Dongen, 2011, A local, bottom-up perspective on sleep deprivation and neurobehavioral performance, Curr Top Med Chem., 11, 2414, 10.2174/156802611797470286 · DOI
  62. Rector, 2005, Local functional state differences between rat cortical columns, Brain Res., 1047, 45, 10.1016/j.brainres.2005.04.002 · DOI
  63. Nir, 2017, Selective neuronal lapses precede human cognitive lapses following sleep deprivation, Nat Med., 23, 1474, 10.1038/nm.4433 · DOI
  64. Åkerstedt, 2014, Subjective sleepiness is a sensitive indicator of insufficient sleep and impaired waking function, J Sleep Res., 23, 242, 10.1111/jsr.12158 · DOI
  65. Watson, 1988, Development and validation of brief measures of positive and negative affect: the PANAS scales, J Pers Soc Psychol., 54, 1063, 10.1037/0022-3514.54.6.1063 · DOI · Paper page
  66. Hudson, 2022, Effects of total sleep deprivation on performance on a continuous performance matching task, Sleep., 45, A530119, 10.1093/sleep/zsac079.117 · DOI
  67. Honn, 2020, New insights into the cognitive effects of sleep deprivation by decomposition of a cognitive throughput task, Sleep., 43, zsz319, 10.1093/sleep/zsz319 · DOI
  68. Basner, 2021, Response speed measurements on the psychomotor vigilance test: how precise is precise enough?, Sleep., 44, zsaa121, 10.1093/sleep/zsaa121 · DOI · Paper page
  69. Ratcliff, 2011, Diffusion model for one-choice reaction-time tasks and the cognitive effects of sleep deprivation, Proc Natl Acad Sci USA., 108, 11285, 10.1073/pnas.1100483108 · DOI
  70. Walsh, 2017, Computational cognitive modeling of the temporal dynamics of fatigue from sleep loss, Psychon Bull Rev., 24, 1785, 10.3758/s13423-017-1243-6 · DOI
  71. Honn, 2018, Total sleep deprivation does not significantly degrade semantic encoding, Chronobiol Int., 35, 746, 10.1080/07420528.2017.1411361 · DOI
  72. Fournier, 2020, Action plan interrupted: resolution of proactive interference while coordinating execution of multiple action plans during sleep deprivation, Psychol Res., 84, 454, 10.1007/s00426-018-1054-z · DOI
  73. Hudson, 2020, Speed/accuracy trade-off in the effects of acute total sleep deprivation on a sustained attention and response inhibition task, Chronobiol Int., 37, 1441, 10.1080/07420528.2020.1811718 · DOI
  74. Wilkinson, 1961, Interaction of lack of sleep with knowledge of results, repeated testing, and individual differences, J Exp Psychol., 62, 263, 10.1037/h0048787 · DOI
  75. Chee, 2013, Functional imaging of inter-individual differences in response to sleep deprivation., 154, 10.1017/CBO9781139088268.021 · DOI
  76. Warm, 2008, Vigilance requires hard mental work and is stressful, Hum Factors., 50, 433, 10.1518/001872008X312152 · DOI
  77. Van Dongen, 2000, Circadian rhythms in fatigue, alertness, and performance., 391
  78. Li, 2013, Age-related frontoparietal changes during the control of bottom-up and top-down attention: an ERP study, Neurobiol Aging., 34, 477, 10.1016/j.neurobiolaging.2012.02.025 · DOI

Cited by

Sorted by citations

See all 9

Metadata

Authors
Honn, K. A., & Van Dongen, H. P. A.
Affiliations
Sleep and Performance Research Center and Department of Translational Medicine and Physiology, Washington State University , Spokane, WA , USA
ORCID
Venue
SLEEP Advances
Publisher
Oxford University Press (OUP)
Published
2022-12-07
Volume
4
Issue
1
ISSN
2632-5012
DOI
10.1093/sleepadvances/zpac045
PMC
PMC10108643
Cited by
9
References
7
Language
en
Licence
creativecommons.org/licenses/by-nc-nd/4.0/ (vor)
Funders
  • Office of the Assistant Secretary of Defense for Health Affair (W81XWH-16-1-0319)
  • Peer Reviewed Medical Research Program Expansion (W81XWH-20-1-0442)
  • Department of Defense

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Paradoxical effects from stimulus density manipulation provide new insight into the impact of sleep deprivation on PVT performance. https://app.cochat.ai/papers/10.1093/sleepadvances/zpac045
The paper
Honn, K. A., & Van Dongen, H. P. A. (2023). Paradoxical effects from stimulus density manipulation provide new insight into the impact of sleep deprivation on PVT performance. SLEEP Advances. https://doi.org/10.1093/sleepadvances/zpac045