A Controlled Study of a Group Mindfulness Intervention for Individuals Living With Inflammatory Bowel Disease
Abstract
BACKGROUND: This study aimed to evaluate the feasibility, acceptability, and effectiveness of a mindfulness-based intervention for patients with inflammatory bowel disease (MI-IBD). DESIGN: Treatment-as-usual control versus mindfulness-based stress reduction intervention. METHODS: Sixty patients participated in either the MI-IBD (n = 33) or treatment-as-usual group (n = 27) conditions. The MI-IBD consisted of an 8-week mindfulness-based stress reduction training group. Outcome measures were administered at baseline (before intervention), immediately after intervention, and 6 months after intervention. Primary outcomes included measures of quality of life, psychological distress (depression and anxiety), and mindfulness. Data for MI-IBD group participants also included weekly attendance, daily minutes meditated, and satisfaction with the program. RESULTS: There were no baseline differences between intervention and control groups on demographic variables or inflammatory bowel disease severity. Compared with the control group, the MI-IBD group reported significantly greater improvements in anxiety, quality of life, and mindfulness at after intervention, with reduction in depression and improvements in quality of life and mindfulness maintained at 6 months after intervention. CONCLUSIONS: Results demonstrate the feasibility, acceptability, and efficacy of a mindfulness intervention for patients with inflammatory bowel disease, with medium-to-large effects on psychological distress, quality of life, and mindfulness.
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In the mindfulness trial, immediate post-treatment effect sizes ranged from medium to large (d = 0.56, 1.27), and durable effects at six months post-treatment (d = 0.45 to 1.38) were found.
“Immediate post-treatment effect sizes ranging from medium to large (d = 0.56, 1.27), and durable effects at six months post-treatment (d = 0.45 to 1.38) were found (66).”
From The 2023 Impact of Inflammatory Bowel Disease in Canada: Mental Health and Inflammatory Bowel Disease (2023) · cites this paper as [66]
The Longitudinal Questionnaire Outcomes section reports immediate post-treatment effect sizes of d = 0.56–1.27. At 32 weeks, approximately six months after treatment, it reports statistically significant effects of d = 0.70–1.38. Table 3 also lists d = 0.45 for anxiety at 32 weeks, but that effect was not statistically significant, so the claim overstates the range of durable effects. (LLM, conf=0.88)
Experimental — accuracy not yet measuredGroup programmes that included meditation or mindfulness or Acceptance-Commitment Therapy reduced distress and perceived stress.
“Group programmes that included meditation or mindfulness 37 , 39 , 52 or Acceptance‐Commitment Therapy 58 reduced distress and perceived stress.”
From Systematic review: the role of psychological stress in inflammatory bowel disease (2022) · cites this paper as [52]
The Procedure describes a group mindfulness programme that included meditation, and Longitudinal Questionnaire Outcomes reports greater improvements in anxiety and depression than in the control group, supporting reduced psychological distress. This study did not report a reduction in perceived stress as an outcome. The Acceptance and Commitment Therapy portion is attached to a different citation. (LLM, conf=0.84)
Experimental — accuracy not yet measuredA controlled mindfulness trial for people with IBD, using a group-based treatment protocol over eight sessions compared to treatment as usual, found significant improvement in measures of anxiety, depression, and quality of life for those engaged in the mindfulness program.
“A controlled mindfulness trial for people with IBD, using a group-based treatment protocol over eight sessions compared to treatment as usual, also found significant improvement in measures of anxiety, depression, and quality of life for those engaged in the mindfulness program.”
From The 2023 Impact of Inflammatory Bowel Disease in Canada: Mental Health and Inflammatory Bowel Disease (2023) · cites this paper as [66]
All included studies took place in Europe or North America, except for two in Australia, one in China, and one online study with participants from multiple countries.
“All took place in either Europe or North America, except for two studies in Australia, 44 , 52 one in China 46 and one online study by researchers based on Canada and the UK and whose participants were from North America, UK and ‘other’ countries (not described). 55”
From Systematic review: the role of psychological stress in inflammatory bowel disease (2022) · cites this paper as [52]
Only one intervention study reported a cost-benefit analysis of whether intervention benefits outweighed harms.
“and only one reported a cost–benefit analysis of whether intervention benefits outweighed harms (Table S3). 52”
From Systematic review: the role of psychological stress in inflammatory bowel disease (2022) · cites this paper as [52]
The Statistical Analyses section describes comparisons of intervention outcomes, and the Discussion reports benefits and notes the burden of daily practice. Neither reports a cost–benefit analysis weighing benefits against harms. Searches for “cost benefit,” “harms,” and adverse effects found no passage establishing that this study performed such an analysis or was the only intervention study to do so; page numbers were unavailable in our copy. (LLM, conf=0.77)
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Self-citation
- Authors
- Neilson, K., Ftanou, M., Monshat, K., Salzberg, M., Bell, S., Kamm, M. A., Connell, W., Knowles, S. R., Sevar, K., Mancuso, S. G., & Castle, D.
- Affiliations
- The University of Melbourne (AU)
- St Vincent's Hospital Melbourne (AU)
- Venue
- Inflammatory Bowel Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-03
- Volume
- 22
- Issue
- 3
- Pages
- 694-701
- ISSN
- 1078-0998 (ISSN-L)
- OpenAlex
- W2194107072
- Semantic Scholar
- 1966189eb4b45672d76def2df45555d498ea1f78
- Cited by
- 80
- References
- 48
- Citations by year
- 2025: 8 · 2024: 10 · 2023: 8 · 2022: 10 · 2021: 10 · 2020: 7 · 2019: 9 · 2018: 8 · 2017: 6 · 2016: 3 · 2015: 1
- FWCI
- 7.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Inflammatory Bowel Diseases (publishedVersion)
- PubMed (publishedVersion)
- Swinburne figshare (Swinburne University of Technology) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- inflammatory bowel disease, mindfulness-based stress reduction
- MeSH terms
- Adult, Aged, Anxiety, Depression, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prognosis, Quality of Life, Surveys and Questionnaires, Research Design, Stress, Psychological, Inflammatory Bowel Diseases, Case-Control Studies, Outcome Assessment, Health Care, Early Intervention, Educational, Young Adult, Mindfulness
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