Single-cell RNA expression profiling of ACE2, the receptor of SARS-CoV-2

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SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

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Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

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Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

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Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues

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SARS-CoV-2 productively infects human gut enterocytes

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COVID-19 and cardiovascular disease

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Seasonality of Respiratory Viral Infections

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SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells

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New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

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Machine learning using intrinsic genomic signatures for rapid classification of novel pathogens: COVID-19 case study

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COVID-19 and Multiorgan Response

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Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection

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Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: A Retrospective Case Series StudyPreprint

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Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

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Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia

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Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools

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SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far

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Understanding of COVID‐19 based on current evidence

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Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China

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Clinical characteristics of 82 cases of death from COVID-19

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COVID-19: A promising cure for the global panic

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scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells

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Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

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Clinical characteristics and outcomes of patients with severe COVID-19 with diabetes

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Guillain Barre syndrome associated with COVID-19 infection: A case report

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Coronavirus: Why Men are More Vulnerable to Covid-19 Than Women?

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Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19)

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Face Masks in the New COVID-19 Normal: Materials, Testing, and Perspectives

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Is ethnicity linked to incidence or outcomes of covid-19?

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COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome?

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Insight into 2019 novel coronavirus — An updated interim review and lessons from SARS-CoV and MERS-CoV

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COVID-19 infection and rheumatoid arthritis: Faraway, so close

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Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

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The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future

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ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy

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Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract

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The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study

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Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids

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Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China

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COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-Chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?

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Saliva: potential diagnostic value and transmission of 2019-nCoV

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APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort

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Coronavirus disease (COVID‐19) and neonate: What neonatologist need to know

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Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis

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Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor

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Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: A retrospective study of 168 severe patients

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Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection

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COVID-19 Pandemic: Prevention and Protection Measures to Be Adopted at the Workplace

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Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells

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Racial and Gender-Based Differences in COVID-19

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Oral Manifestations in Patients with COVID-19: A Living Systematic Review

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mRNA vaccines for COVID-19: what, why and how

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Coronavirus 2019-nCoV: A brief perspective from the front line

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A Randomized Clinical Trial of the Efficacy and Safety of Interferon β-1a in Treatment of Severe COVID-19

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Overview of lethal human coronaviruses

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Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence

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Effect of SARS-CoV-2 infection upon male gonadal function: A single center-based studyPreprint

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Current status of potential therapeutic candidates for the COVID-19 crisis

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Three-dimensional human alveolar stem cell culture models reveal infection response to SARS-CoV-2

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The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity

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The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment

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ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

Benetti, E., Tita, R., Spiga, O., Ciolfi, A., Birolo, G., Bruselles, A., Doddato, G., Giliberti, A., Marconi, C., Musacchia, F., et al. (2020) · European Journal of Human Genetics · doi:10.1038/s41431-020-0691-z · Cited by 262

Updated Approaches against SARS-CoV-2

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SARS-CoV-2 Productively Infects Human Gut EnterocytesPreprint

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A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors

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Is the kidney a target of SARS-CoV-2?

Martínez-Rojas, M. A., Vega‐Vega, O., & Bobadilla, N. A. (2020) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00160.2020 · Cited by 241

The immunology of COVID-19: is immune modulation an option for treatment?

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Patient-derived SARS-CoV-2 mutations impact viral replication dynamics and infectivity in vitro and with clinical implications in vivo

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Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cellsPreprint

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Prolonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19

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COVID-19 Infection and Circulating ACE2 Levels: Protective Role in Women and Children

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Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications

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Detection profile of SARS‐CoV‐2 using RT‐PCR in different types of clinical specimens: A systematic review and meta‐analysis

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Subjective neurological symptoms frequently occur in patients with SARS-CoV2 infection

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Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression

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Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): a Systemic Infection

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Neurological Manifestations of COVID-19 (SARS-CoV-2): A Review

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Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection

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Single-cell analysis of human lung epithelia reveals concomitant expression of the SARS-CoV-2 receptor ACE2 with multiple virus receptors and scavengers in alveolar type II cellsPreprint

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Abstract 702: Single-cell expression landscape of SARS-CoV-2 receptor ACE2 and host proteases in human lung adenocarcinoma

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The protein expression profile of ACE2 in human tissues

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Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCoV, in the nasal tissuePreprint

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Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

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