Baricitinib as potential treatment for 2019-nCoV acute respiratory disease
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Based on an in-house drug discovery knowledge graph, BenevolentAI scientists proposed baricitinib, at the time approved for rheumatoid arthritis, as a drug repurposing candidate for severe COVID-19.
“Based on an in-house drug discovery knowledge graph, BenevolentAI scientists proposed baricitinib, at the time approved for rheumatoid arthritis, as a drug repurposing candidate for severe COVID-19 (52,53).”
From DrugCentral 2023 extends human clinical data and integrates veterinary drugs (2023) · cites this paper as [52]
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- Authors
- Richardson, P., Griffin, I., Tucker, C., Smith, D., Oechsle, O., Phelan, A., Rawling, M., Savory, E., & Stebbing, J.
- Affiliations
- BenevolentAI (United Kingdom) (GB)
- Imperial College London (GB)
- Corresponding author
- Stebbing, Justin
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 395
- Issue
- 10223
- Pages
- e30-e31
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- PMC
- PMC7137985
- OpenAlex
- W3004919484
- Cited by
- 1,456
- References
- 12
- Citations by year
- 2026: 50 · 2025: 65 · 2024: 61 · 2023: 121 · 2022: 197 · 2021: 371 · 2020: 585 · 2019: 3 · 2014: 1 · 2012: 1
- FWCI
- 41.96
- Type
- journal article
- Language
- en
- Update notices
- erratum (2020-06-20)
- Open access
- bronze
- doi.org
- Locations
- The Lancet (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Figshare (submittedVersion, cc-by-nc-nd)
- Funders
- National Institute for Health and Care Research (NIHR-RP-011-053)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
- Keywords
- baricitinib, SARS-CoV-2, COVID-19 pandemic, acute respiratory illness, antiviral therapy, JAK inhibitors, lopinavir/ritonavir, drug repurposing
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, COVID-19 Drug Treatment, Azetidines, Humans, Pneumonia, Viral, Purines, Pyrazoles, Sulfonamides, Coronavirus Infections, Pandemics
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