Cited by 1,456COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchRespiratory viral infections research

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease

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Richardson, Peter, Griffin, Ivan, Tucker, Catherine, Smith, Dan, Oechsle, Olly, Phelan, Anne, Rawling, Michael, Savory, Edward +1 more·2020·The Lancet

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Crossref · 10.1016/s0140-6736(20)30304-4

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  • Based on an in-house drug discovery knowledge graph, BenevolentAI scientists proposed baricitinib, at the time approved for rheumatoid arthritis, as a drug repurposing candidate for severe COVID-19.

    “Based on an in-house drug discovery knowledge graph, BenevolentAI scientists proposed baricitinib, at the time approved for rheumatoid arthritis, as a drug repurposing candidate for severe COVID-19 (52,53).”

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Research works printed but not linked: 1

  1. [3]Zhao Y Zhao Z Wang Y Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov BioRxiv 2020 published online Jan 26. DOI:https://doi.19985

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Authors
Richardson, P., Griffin, I., Tucker, C., Smith, D., Oechsle, O., Phelan, A., Rawling, M., Savory, E., & Stebbing, J.
Affiliations
  • BenevolentAI (United Kingdom) (GB)
  • Imperial College London (GB)
Corresponding author
Stebbing, Justin
Venue
The Lancet
Publisher
Elsevier BV
Published
2020-02
Volume
395
Issue
10223
Pages
e30-e31
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W3004919484
Cited by
1,456
References
12
Citations by year
2026: 50 · 2025: 65 · 2024: 61 · 2023: 121 · 2022: 197 · 2021: 371 · 2020: 585 · 2019: 3 · 2014: 1 · 2012: 1
FWCI
41.96
Type
journal article
Language
en
Update notices
erratum (2020-06-20)
Open access
Locations
  • The Lancet (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Figshare (submittedVersion, cc-by-nc-nd)
Funders
National Institute for Health and Care Research (NIHR-RP-011-053)
Topics
  • Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
  • Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
Keywords
baricitinib, SARS-CoV-2, COVID-19 pandemic, acute respiratory illness, antiviral therapy, JAK inhibitors, lopinavir/ritonavir, drug repurposing
MeSH terms
Betacoronavirus, COVID-19, SARS-CoV-2, COVID-19 Drug Treatment, Azetidines, Humans, Pneumonia, Viral, Purines, Pyrazoles, Sulfonamides, Coronavirus Infections, Pandemics

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