BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

Miki, Y., Swensen, J. J., Shattuck-Eidens, D. M., Futreal, P. A., Harshman, K., Tavtigian, S. V., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., et al. (1994) · Science · doi:10.1126/science.7545954 · Cited by 6,069

Lessons from hereditary colorectal cancer

Kinzler, K. W., & Vogelstein, B. (1996) · Cell · doi:10.1016/s0092-8674(00)81333-1 · Cited by 4,919

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., et al. (1995) · Science · doi:10.1126/science.7792600 · Cited by 2,785

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Canman, C. E., Lim, D.-S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., & Siliciano, J. D. (1998) · Science · doi:10.1126/science.281.5383.1677 · Cited by 2,042

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

Banin, S., Moyal, L., Shieh, S.-Y., Taya, Y., Anderson, C. W., Chessa, L., Smorodinsky, N. I., Prives, C., Reiss, Y., Shiloh, Y., et al. (1998) · Science · doi:10.1126/science.281.5383.1674 · Cited by 1,797

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T., & Livingston, D. M. (1997) · Cell · doi:10.1016/s0092-8674(00)81847-4 · Cited by 1,459

The Bloom's syndrome gene product is homologous to RecQ helicases

Ellis, N. A., Groden, J. L., Ye, T.-Z., Straughen, J. E., Lennon, D. J., Ciocci, S., Proytcheva, M. A., & GERMAN, J. L. (1995) · Cell · doi:10.1016/0092-8674(95)90105-1 · Cited by 1,385

BRCA1 mutations in primary breast and ovarian carcinomas.

Futreal, P., Liu, Q., Shattuck-Eidens, D., Cochran, C., Harshman, K., Tavtigian, S., Bennett, L., Haugen-Strano, A., Swensen, J., & Miki, Y. (1994) · Science · doi:10.1126/science.7939630 · Cited by 1,378

Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase

Matsuoka, S. (1998) · Science · doi:10.1126/science.282.5395.1893 · Cited by 1,322

SUMO, the Three Rs and Cancer

Seeler, J.-S., Bischof, O., Nacerddine, K., & Dejean, A. (2007) · Springer eBooks · doi:10.1007/978-3-540-34594-7_4 · Cited by 68

Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network

Greenberg, R. A. (2008) · Chromosoma · doi:10.1007/s00412-008-0154-8 · Cited by 69

The S phase checkpoint: When the crowd meets at the fork

Gottifredi, V., & Prives, C. L. (2005) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2005.02.011 · Cited by 68

Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype.

Spring, K. J., Cross, S., Li, C., Watters, D. J., Ben-Senior, L., Waring, P., Ahangari, F., Lu, S. L., Chen, P., MISKO, I. S., et al. (2001) · PubMed · Cited by 68

DNA polymerase stalling, sister chromatid recombination and the BRCA genes

Scully, R., Puget, N., & Vlasáková, K. (2000) · Oncogene · doi:10.1038/sj.onc.1203971 · Cited by 68

Role of Anillin in Tumour: From a Prognostic Biomarker to a Novel Target

Nguyen, T. M., & Lee, C. H. (2020) · Cancers · doi:10.3390/cancers12061600 · Cited by 67

Controlling Abl: auto-inhibition and co-inhibition?

Wang, J. Y. J. (2004) · Nature Cell Biology · doi:10.1038/ncb0104-3 · Cited by 67

Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and nonmalignant MCF-10A cells

Francisco, D., Peddi, P., Hair, J. M., Flood, B., Cecil, A. M., Kalogerinis, P. T., Sigounas, G., & Georgakilas, A. G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.10.045 · Cited by 67

Molecular analysis of sister chromatid recombination in mammalian cells

Puget, N., Knowlton, M. L., & Scully, R. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.08.010 · Cited by 67

Functions of BLM Helicase in Cells: Is It Acting Like a Double-Edged Sword?

Kaur, E., Agrawal, R., & Sengupta, S. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.634789 · Cited by 71

The molecular mechanism of DNA damage recognition by MutS homologs and its consequences for cell death response

Salsbury, F. R. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl238 · Cited by 66

The DNA double-strand break response pathway: becoming more BRCAish than ever

Ting, N. S. Y., & Lee, W. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.03.026 · Cited by 67

Identification of rad27 Mutations That Confer Differential Defects in Mutation Avoidance, Repeat Tract Instability, and Flap Cleavage

Xie, Y., Liu, Y., Argueso, J. L., Henricksen, L. A., Kao, H.-I., Bambara, R. A., & Alani, E. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.15.4889-4899.2001 · Cited by 67

Involvement of Homologous Recombination in Carcinogenesis

Reliene, R., Bishop, A. J. R., & Schiestl, R. H. (2007) · Advances in genetics · doi:10.1016/s0065-2660(06)58003-4 · Cited by 66

RINT-1, a Novel Rad50-interacting Protein, Participates in Radiation-induced G2/M Checkpoint Control

Xiao, J., Liu, C.-C., Chen, P., & Lee, W. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008893200 · Cited by 67

Crosslinks and crosstalk

Risinger, M. A., & Groden, J. L. (2004) · Cancer Cell · doi:10.1016/j.ccr.2004.12.001 · Cited by 65

Immunohistochemical Expression of DNA Repair Proteins in Familial Breast Cancer DifferentiateBRCA2-Associated Tumors

Honrado, E., Osório, A., Palacios, J., Milne, R. L., Sánchez, L., Dı́ez, O., Cazorla, A., Syrjäkoski, K., Huntsman, D. D., Heikkilä, P., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.01.3698 · Cited by 65

The role of BRCA1 in non-homologous end-joining

Bau, D., Mau, Y.-C., & Shen, C. (2005) · Cancer Letters · doi:10.1016/j.canlet.2005.08.003 · Cited by 65

Cloning of novel mammary tumor progression and metastasis genes

Kimm, M. A., Boer, M., Gaemers, I. C., & Hilkens, J. (2001) · Breast Cancer Research · doi:10.1186/bcr362 · Cited by 65

Collaboration of Brca1 and Chk2 in tumorigenesisPreprint

McPherson, J. P., Lemmers, B., Hirao, A., Hakem, A., Abraham, J., Migon, E., Matysiak‐Zablocki, E., Tamblyn, L., Sanchez-Sweatman, O. H., Khokha, R., et al. (2004) · Genes & Development · doi:10.1101/gad.1192704 · Cited by 67

AID Binds Cooperatively with UNG and Msh2-Msh6 to Ig Switch Regions Dependent upon the AID C Terminus

Ranjit, S., Khair, L., Linehan, E. K., Ucher, A. J., Chakrabarti, M., Schrader, C. E., & Stavnezer, J. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1101406 · Cited by 64

Nonsense mutation p.Q548X in BLM, the gene mutated in Bloom’s syndrome, is associated with breast cancer in Slavic populations

Prokofyeva, D. S., Bogdanova, N. V., Dubrowinskaja, N., Bermisheva, M., Takhirova, Z., Antonenkova, N., Turmanov, N., Datsyuk, I., Gantsev, S. K., Christiansen, H., et al. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-2357-1 · Cited by 64

Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.

Lee, J. H., Xu, B., Lee, C. H., Ahn, J.-Y., Song, M. S., Lee, H., Canman, C. E., Lee, J., Kastan, M. B., & Lim, D. (2003) · PubMed · Cited by 65

Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair

Shahi, A., Lee, J.-H., Kang, Y., Lee, S. H., Hyun, J. W., Chang, I. Y., Jun, J. Y., & You, H. J. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1095 · Cited by 63

Polymorphisms of Homologous Recombination Genes and Clinical Outcomes of Non-Small Cell Lung Cancer Patients Treated with Definitive Radiotherapy

Yin, M., Liao, Z. X., Huang, Y.-J., Liu, Z., Yuan, X., Gomez, D. R., Wang, L., & Wei, Q. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020055 · Cited by 63

Checkpoint genes in cancer

McDonald, E. R., & El‐Deiry, W. S. (2001) · Annals of Medicine · doi:10.3109/07853890109002066 · Cited by 64

The gene regulatory network for breast cancer: integrated regulatory landscape of cancer hallmarks

Emmert‐Streib, F., Simoes, R. D. M., Mullan, P. B., Haibe‐Kains, B., & Dehmer, M. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00015 · Cited by 63

Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women <=55 years

Lü, J., Wei, Q., Bondy, M. L., Li, D., Brewster, A. M., Shete, S. S., Yu, T., Sahin, A., Meric‐Bernstam, F., Hunt, K. K., et al. (2006) · Carcinogenesis · doi:10.1093/carcin/bgl077 · Cited by 62

The BLM helicase is necessary for normal DNA double-strand break repair.

Langland, G. T., Elliott, J., Li, Y., Creaney, J., Dixon, K., & Groden, J. L. (2002) · PubMed · Cited by 62

Live Cell Imaging of Heavy-Ion-Induced Radiation Responses by Beamline Microscopy

Jakob, B., Rudolph, J. H., Gueven, N., Lavin, M. F., & Taucher-Scholz, G. (2005) · Radiation Research · doi:10.1667/rr3374 · Cited by 63

The BRCT Regions of Tumor Suppressor BRCA1 and of XRCC1 Show DNA End Binding Activity with a Multimerizing Feature

Yamane, K., Katayama, E., & TSURUO, T. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3983 · Cited by 62

BLM, the Bloom’s syndrome protein, varies during the cell cycle in its amount, distribution, and co-localization with other nuclear proteins

Sanz, M. M., Proytcheva, M. A., Ellis, N. A., Holloman, W. K., & German, J. (2000) · Cytogenetic and Genome Research · doi:10.1159/000056848 · Cited by 61

Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1

Wang, Q., Zhang, H., Guerrette, S., Chen, J., Mazurek, A., Wilson, T., Słupianek, A., Skórski, T., Fishel, R. A., & Greene, M. I. (2001) · Oncogene · doi:10.1038/sj.onc.1204625 · Cited by 61

Independence of R/M/N Focus Formation and the Presence of Intact BRCA1

Wu, X. (2000) · Science · doi:10.1126/science.289.5476.11a · Cited by 61

Random walks and cell size

Agutter, P. S., & Wheatley, D. N. (2000) · BioEssays · doi:10.1002/1521-1878(200011)22:11 · Cited by 56

Molecular Signature and Mechanisms of Hepatitis D Virus–Associated Hepatocellular Carcinoma

Diaz, G., Engle, R. E., Tice, A. B., Melis, M., Montenegro, S., Rodriguez‐Canales, J., Hanson, J. C., Emmert‐Buck, M. R., Bock, K. W., Moore, I. N., et al. (2018) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-18-0012 · Cited by 60

BRCA1 DNA-Binding Activity Is Stimulated by BARD1

Simons, A. M., Horwitz, A. A., Starita, L. M., Griffin, K., Williams, R. S., Glover, J. N. M., & Parvin, J. D. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3296 · Cited by 63

BRCA1 and Oxidative Stress

Yi, Y. W., Kang, H. J., & Bae, I. (2014) · Cancers · doi:10.3390/cancers6020771 · Cited by 65

BRCA1 and BRCA2: The genetic testing and the current management options for mutation carriers

Palma, M., Ristori, E., Ricevuto, E., Giannini, G., & Gulino, A. (2005) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2005.05.003 · Cited by 61

Localization of checkpoint and repair proteins in eukaryotes

Lisby, M., & Rothstein, R. J. (2004) · Biochimie · doi:10.1016/j.biochi.2004.10.023 · Cited by 61

Control of Translocations between Highly Diverged Genes by Sgs1, the Saccharomyces cerevisiae Homolog of the Bloom'sSyndrome Protein

Schmidt, K. H., Wu, J., & Kolodner, R. D. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00161-06 · Cited by 60

Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase

Schawalder, J., Paric, E., & Neff, N. F. (2003) · BMC Cell Biology · doi:10.1186/1471-2121-4-15 · Cited by 60

Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer

Karakoyun, H. K., Yüksel, Ş., Amanoglu, I., Naserikhojasteh, L., Yeşilyurt, A., Yakıcıer, C., Timuçin, E., & Akyerli, C. B. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1052383 · Cited by 66

Susceptibility to DNA Damage as a Molecular Mechanism for Non-Syndromic Cleft Lip and Palate

Kobayashi, G. S., Alvizi, L., Sunaga, D. Y., Francis‐West, P. H., Kuta, A., Almada, B. V. P., Ferreira, S. G., de Andrade-Lima, L. C., Bueno, D. F., Raposo-Amaral, C. E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065677 · Cited by 59

Redistribution of BRCA1 among Four Different Protein Complexes following Replication Blockage

Chiba, N., & Parvin, J. D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105227200 · Cited by 60

Distinct Pathways of Nonhomologous End Joining That Are Differentially Regulated by DNA-dependent Protein Kinase-mediated Phosphorylation

Udayakumar, D., Bladen, C. L., Hudson, F. Z., & Dynan, W. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306470200 · Cited by 60

SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11

Digweed, M., Demuth, I., Rothe, S., Scholz, R., Jordan, A., Grötzinger, C., Schindler, D., Grompe, M., & Sperling, K. (2002) · Oncogene · doi:10.1038/sj.onc.1205616 · Cited by 59

BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation

Yan, Y., Spieker, R. S., Kim, M., Stoeger, S. M., & Cowan, K. H. (2005) · Oncogene · doi:10.1038/sj.onc.1208492 · Cited by 58

A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage

Hohenstein, P., Kielman, M. F., Breukel, C., Bennett, L. M., Wiseman, R. W., Krimpenfort, P., Cornelisse, C. J., van Ommen, G. B., Devilee, P., & Fodde, R. (2001) · Oncogene · doi:10.1038/sj.onc.1204363 · Cited by 58

hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair

Vo, A. T., Zhu, F., Wu, X., Yuan, F., Gao, Y., Gu, L., Li, G., Lee, T., & Her, C. (2005) · EMBO Reports · doi:10.1038/sj.embor.7400392 · Cited by 58

HERC2 Facilitates BLM and WRN Helicase Complex Interaction with RPA to Suppress G-Quadruplex DNA

Wu, W., Rokutanda, N., Takeuchi, J., Lai, Y., Maruyama, R., Togashi, Y., Nishikawa, H., Arai, N., Miyoshi, Y., Suzuki, N., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-1877 · Cited by 57

Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer

Nair, J. R., Huang, T., Murai, J., Haynes, B. M., Steeg, P. S., Pommier, Y. G., & Lee, J.-M. (2020) · Oncogene · doi:10.1038/s41388-020-1383-4 · Cited by 57

Fanconi anemia and Bloom's syndrome crosstalk through FANCJ–BLM helicase interaction

Suhasini, A. N., & Brosh, R. M. (2011) · Trends in Genetics · doi:10.1016/j.tig.2011.09.003 · Cited by 57

The PCNA-associated factor KIAA0101/p15 binds the potential tumor suppressor product p33ING1b

Simpson, F., LAMMERTSVANBUEREN, K., Butterfield, N. C., Bennetts, J. S., Bowles, J., Adolphe, C., Simms, L. A., Young, J. P., Walsh, M. P., & Leggett, B. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2005.09.020 · Cited by 57

BRCA1 and Its Network of Interacting Partners

Christou, C. M., & Kyriacou, K. C. (2013) · Biology · doi:10.3390/biology2010040 · Cited by 58

Fanconi Anemia Group J Helicase and MRE11 Nuclease Interact To Facilitate the DNA Damage Response

Suhasini, A. N., Sommers, J. A., Muniandy, P. A., Coulombe, Y., Cantor, S. B., Masson, J., Seidman, M. M., & Brosh, R. M. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01256-12 · Cited by 57

Modification of Homologous Recombination Deficiency Score Threshold and Association with Long-Term Survival in Epithelial Ovarian Cancer

How, J., Jazaeri, A. A., Fellman, B. M., Daniels, M. S., Penn, S., Solimeno, C., Yuan, Y., Schmeler, K. M., Lanchbury, J. S. S., Timms, K. M., et al. (2021) · Cancers · doi:10.3390/cancers13050946 · Cited by 57

Gene Signature of Breast Cancer Cell Lines Treated with Lycopene

Chalabi, N., Delort, L., Corre, L. L., Satih, S., Bignon, Y., & Bernard-Gallon, D. J. (2006) · Pharmacogenomics · doi:10.2217/14622416.7.5.663 · Cited by 57

Altered expression of DNA double‐strand break detection and repair proteins in breast carcinomas

Angèle, S., Treilleux, I., Bremond, A. G., Tanière, P., & Hall, J. A. (2003) · Histopathology · doi:10.1046/j.1365-2559.2003.01713.x · Cited by 57

Nuclear translocation contributes to regulation of DNA excision repair activities

Knudsen, N. Ø., Andersen, S. D., Lützen, A., Nielsen, F. C., & Rasmussen, L. J. (2009) · DNA Repair · doi:10.1016/j.dnarep.2009.03.005 · Cited by 56

Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells

Lan, L., Hayashi, T., Rabeya, R. M., Nakajima, S., Kanno, S., Takao, M., Matsunaga, T., Yoshino, M., Ichikawa, M., Riele, H. T., et al. (2003) · DNA repair · doi:10.1016/j.dnarep.2003.10.005 · Cited by 56

BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest

Ongusaha, P. P., Ouchi, T., Kim, K., Nytko, E. A., Kwak, J. C., Duda, R. B., Deng, C., & Lee, S. W. (2003) · Oncogene · doi:10.1038/sj.onc.1206439 · Cited by 56

Splicing DNA-damage responses to tumour cell death

Crighton, D., & Ryan, K. M. (2004) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2004.09.001 · Cited by 56

The cell cycle and DNA mismatch repair

Schroering, A. G., Edelbrock, M. A., Richards, T. J., & Williams, K. J. (2006) · Experimental Cell Research · doi:10.1016/j.yexcr.2006.10.018 · Cited by 56

BRCA1 and p53: compensatory roles in DNA repair

Hartman, A., & Ford, J. M. (2003) · Journal of Molecular Medicine · doi:10.1007/s00109-003-0477-0 · Cited by 62

Disruption of the Fanconi anemia/BRCA pathway in sporadic cancer

Lyakhovich, A., & Surrallés, J. (2005) · Cancer Letters · doi:10.1016/j.canlet.2005.07.038 · Cited by 56

Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation

Peters, A. (2003) · DNA repair · doi:10.1016/s1568-7864(03)00003-x · Cited by 56

Components of a Pathway Maintaining Histone Modification and Heterochromatin Protein 1 Binding at the Pericentric Heterochromatin in Mammalian Cells

Xin, H., Yoon, H., Singh, P. B., Wong, J., & Qin, J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m311587200 · Cited by 56

Association of p53 and MSH2 with recombinative repair complexes during S phase

Zink, D., Mayr, C., Janz, C., & Wiesmüller, L. (2002) · Oncogene · doi:10.1038/sj.onc.1205614 · Cited by 56

Holding All the Cards—How Fanconi Anemia Proteins Deal with Replication Stress and Preserve Genomic Stability

Datta, A., & Brosh, R. M. (2019) · Genes · doi:10.3390/genes10020170 · Cited by 56

Personalized Medicine for Targeted and Platinum-Based Chemotherapy of Lung and Bladder Cancer

Cimino, G. D., Pan, C.-X., & Henderson, P. T. (2013) · Bioanalysis · doi:10.4155/bio.12.325 · Cited by 58

Mechanisms of Recombination between Diverged Sequences in Wild-Type and BLM-Deficient Mouse and Human Cells

LaRocque, J. R., & Jasin, M. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.01553-09 · Cited by 59

The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers.

Turner, B. C., Ottey, M., Zimonjic, D. B., Potoczek, M., Hauck, W. W., Pequignot, E. C., Keck-Waggoner, C. L., Sevignani, C., Aldaz, C. M., McCue, P. A., et al. (2002) · PubMed · Cited by 55

Chromosome stability, DNA recombination and the BRCA2 tumour suppressor

Venkitaraman, A. R. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00217-9 · Cited by 55

Heat induces γH2AX foci formation in mammalian cells

Takahashi, A., Mori, E., Somakos, G. I., Ohnishi, K., & Ohnishi, T. (2008) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2008.07.012 · Cited by 54

The Unresolved Problem of DNA Bridging

Fernández-Casañas, M., & Chan, K. (2018) · Genes · doi:10.3390/genes9120623 · Cited by 57

Cell Cycle Checkpoint Control Mechanisms That Can Be Disrupted in Cancer

Dash, B. C., & El‐Deiry, W. S. (2004) · Humana Press eBooks · doi:10.1385/1-59259-788-2:099 · Cited by 55

The Bloom's Syndrome Helicase Interacts Directly with the Human DNA Mismatch Repair Protein hMSH6

Pedrazzi, G., Bachrati, C. Z., Selak, N., Stoffel-Studer, I., Petkovic, M., Hickson, I. D., Jiricny, J., & Štagljar, I. (2003) · Biological Chemistry · doi:10.1515/bc.2003.128 · Cited by 54

Genetic alterations in accelerated ageing syndromes

Puzianowska‐Kuźnicka, M., & Kuźnicki, J. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.10.011 · Cited by 54

Activation of DNA damage signaling

Ljungman, M. E. (2005) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2005.02.014 · Cited by 54

Can corruption of chromosome cohesion create a conduit to cancer?

Xu, H., Tomaszewski, J. M., & McKay, M. J. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3018 · Cited by 54

DNA damage, neuronal and glial cell death and neurodegeneration

Barzilai, A. (2010) · APOPTOSIS · doi:10.1007/s10495-010-0501-0 · Cited by 53

Crosstalk between BRCA‐Fanconi anemia and mismatch repair pathways prevents MSH2‐dependent aberrant DNA damage responses

Peng, M., Xie, J., Ucher, A. J., Stavnezer, J., & Cantor, S. B. (2014) · The EMBO Journal · doi:10.15252/embj.201387530 · Cited by 54

Protein kinases and their involvement in the cellular responses to genotoxic stress

Yang, J. J., Yu, Y., & Duerksen-Hughes, P. J. (2003) · Mutation Research/Reviews in Mutation Research · doi:10.1016/s1383-5742(02)00069-8 · Cited by 53

ATM polymorphisms and risk of lung cancer among never smokers

Lo, Y.-L., Hsiao, C., Jou, Y., Chang, G., Tsai, Y., Su, W., Chen, Y., Huang, M., Chen, H., Yang, P., et al. (2009) · Lung Cancer · doi:10.1016/j.lungcan.2009.11.007 · Cited by 52

The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity

Mirzoeva, O. K., Kawaguchi, T., & Pieper, R. O. (2006) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0183 · Cited by 52

Targeting DNA repair in breast cancer: A clinical and translational update

Amir, E., Šeruga, B., Serrano, R., & Ocaña, A. (2010) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2010.03.006 · Cited by 52

ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers

Adem, C., Soderberg, C. L., Hafner, K. A., Reynolds, C. A., Slezak, J. M., Sinclair, C. S., Sellers, T. A., Schaid, D. J., Couch, F. J., Hartmann, L. C., et al. (2004) · Genes Chromosomes and Cancer · doi:10.1002/gcc.20057 · Cited by 52

Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility

Ding, S.-L., Yu, J., Chen, S., Hsu, G., Kuo, S., Lin, Y. H., Wu, P., & Shen, C. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn233 · Cited by 52

Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naive patients

Martı́nez, N., Sánchez‐Beato, M., Carnero, A., Moneo, V., Tercero, J. C., Fernández, I., Navarrete, M., Jimeno, J. M., & Piris, M. A. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-04-0316 · Cited by 52

Interaction of the EWS NH2 terminus with BARD1 links the Ewing's sarcoma gene to a common tumor suppressor pathway.

Spahn, L., Petermann, R., Siligan, C., Schmid, J. A., Aryee, D. N. T., & Kovar, H. (2002) · PubMed · Cited by 52

Defending genome integrity during S-phase: putative roles for RecQ helicases and topoisomerase III

Oakley, T. J., & Hickson, I. D. (2002) · DNA repair · doi:10.1016/s1568-7864(02)00002-2 · Cited by 54

Molecular Anatomy of the DNA Damage and Replication Checkpoints

Qin, J., & Li, L. (2003) · Radiation Research · doi:10.1667/0033-7587(2003)159[0139:maotdd]2.0.co;2 · Cited by 52

EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases

Cousineau, I., & Belmaaza, A. (2011) · Molecular Genetics and Genomics · doi:10.1007/s00438-011-0612-5 · Cited by 57

Lack of the Matricellular Protein SPARC (Secreted Protein, Acidic and Rich in Cysteine) Attenuates Liver Fibrogenesis in Mice

Atorrasagasti, C., Peixoto, E., Aquino, J. B., Kippes, N., Malvicini, M., Alaniz, L. D., García, M. G., Piccioni, F., Fiore, E. J., Bayo, J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054962 · Cited by 54

Intrinsic Radiation Sensitivity: Cellular Signaling is the Key

Szumiel, I. (2008) · Radiation Research · doi:10.1667/rr1239.1 · Cited by 51

MlaA, a hexameric ATPase linked to the Mre11 complex in archaeal genomes

Manzan, A., Pfeiffer, G., Hefferin, M. L., Lang, C. E., Carney, J. P., & Hopfner, K. (2004) · EMBO Reports · doi:10.1038/sj.embor.7400037 · Cited by 51

Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer

Arora, A., Abdel-Fatah, T. M. A., Agarwal, D., Doherty, R. E., Moseley, P. M., Aleskandarany, M. A., Green, A. R., Ball, G., Alshareeda, A. T., Rakha, E. A., et al. (2015) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-14-0939 · Cited by 51

Cancer predisposition genes: molecular mechanisms and clinical impact on personalized cancer care: examples of Lynch and HBOC syndromes

Wang, Q. (2015) · Acta Pharmacologica Sinica · doi:10.1038/aps.2015.89 · Cited by 51

A DNA2 Homolog Is Required for DNA Damage Repair, Cell Cycle Regulation, and Meristem Maintenance in Plants

Jia, N., Liu, X., & Gao, H. (2016) · PLANT PHYSIOLOGY · doi:10.1104/pp.16.00312 · Cited by 51

BASC (BRCA1‐associated genome surveillance complex)

(2008) · Springer eBooks · doi:10.1007/978-1-4020-6754-9_1584

Coordination of BRCA1/BARD1- and MRE11/RAD50/NBS1-dependent DNA Transactions in Breast Tumor Suppression

Gautier, J., & Greene, E. C. (2009) · doi:10.21236/ada519536

Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage

Her, J., Lee, N. S., Kim, Y., & Kim, H. (2016) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmw047 · Cited by 43

Вовлеченность генов белков BRСA1-ассоциированного комплекса наблюдения за геномом (BASC) в развитие многофакторной патологии

Бабушкина, Н. П., Postrigan, A. E., & Николаевна, К. А. (2021) · Molecular Biology · doi:10.31857/s0026898421020038 · Cited by 7

Evaluation of BRCA1 related DNA repair genes in breast and ovarian carcinogenesis

MARESCA, L. (2017) · Electronic Theses and Dissertations Repository (University of Pisa)