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Hypersensitivity of Tumor Cell Lines with Microsatellite Instability to DNA Double Strand Break Producing Chemotherapeutic Agent Bleomycin

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Promotion of DNA end resection by BRCA1–BARD1 in homologous recombination

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PLK1 targets CtIP to promote microhomology-mediated end joining

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Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants

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Comprehensive mismatch repair gene panel identifies variants in patients with Lynch‐like syndrome

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Mutations in the BRCT binding site of BRCA1 result in hyper-recombination

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BRCA1: A New Genomic Marker for Non–Small-Cell Lung Cancer

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The RSF1 Histone-Remodelling Factor Facilitates DNA Double-Strand Break Repair by Recruiting Centromeric and Fanconi Anaemia Proteins

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The Ku complex: recent advances and emerging roles outside of non-homologous end-joining

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BRCA1 role in the mitigation of radiotoxicity and chromosomal instability through repair of clustered DNA lesions

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Genetic and epigenetic features in radiation sensitivity

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Integrative proteogenomic characterization reveals therapeutic targets in poorly differentiated and anaplastic thyroid cancers

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Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis

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Polo‐like kinase 1 inhibition suppresses hepatitis B virus X protein‐induced transformation in an in vitro model of liver cancer progression†

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BRCA1 interacts with FHL2 and enhances FHL2 transactivation function

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Physical and Functional Interaction between the Bloom's Syndrome Gene Product and the Largest Subunit of Chromatin Assembly Factor 1

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Chromosome instability and tumor predisposition inversely correlate with BLM protein levels

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Bloom helicase is involved in DNA surveillance in early S phase in vertebrate cells

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The Werner Syndrome Protein Is Distinguished from the Bloom Syndrome Protein by Its Capacity to Tightly Bind Diverse DNA Structures

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Cancer Risk Assessment Using Genetic Panel Testing: Considerations for Clinical Application

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Rad50 Is Dispensable for the Maintenance and Viability of Postmitotic Tissues

Adelman, C. A., De, S., & Petrini, J. H. J. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01525-08 · Cited by 45

Loss of atm sensitises p53-deficient cells to topoisomerase poisons and antimetabolites

Fedier, A., Schlamminger, M., Schwarz, V. A., Haller, U., Howell, S. B., & Fink, D. A. (2003) · Annals of Oncology · doi:10.1093/annonc/mdg240 · Cited by 45

TLR9 engagement on CD4 T lymphocytes represses γ-radiation–induced apoptosis through activation of checkpoint kinase response elements

Zheng, L., Asprodites, N., Keene, A. H., Rodrı́guez, P. C., Brown, K. D., & Dávila, E. (2007) · Blood · doi:10.1182/blood-2007-07-104141 · Cited by 45

Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population

Yamamoto, H. (2004) · Carcinogenesis · doi:10.1093/carcin/bgh335 · Cited by 45

Accurate Homologous Recombination Is a Prominent Double-Strand Break Repair Pathway in Mammalian Chromosomes and Is Modulated by Mismatch Repair Protein Msh2

Smith, J. A., Bannister, L., Bhattacharjee, V., Wang, Y., Waldman, B. C., & Waldman, A. S. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00455-07 · Cited by 45

The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability

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Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR–Chk1 pathway

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BRCA1 Interacts with and Is Required for Paclitaxel-Induced Activation of Mitogen-Activated Protein Kinase Kinase Kinase 3

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Pharmacogenetic tests in cancer chemotherapy: what physicians should know for clinical application

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Genes, Chromatin, and Breast Cancer: An Epigenetic Tale

Mielnicki, L. M., Asch, H. L., & Asch, B. B. (2001) · Journal of Mammary Gland Biology and Neoplasia · doi:10.1023/a:1011356623442 · Cited by 44

Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis.

Cheung, A., Hande, M. P., Jalali, F., Tsao, M., Skinnider, B., Hirao, A., McPherson, J. P., Karásková, J., Suzuki, A., Wakeham, A. C., et al. (2002) · PubMed · Cited by 44

DNA Lesion-specific Co-localization of the Mre11/Rad50/Nbs1 (MRN) Complex and Replication Protein A (RPA) to Repair Foci

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A novel time-course cDNA microarray analysis method identifies genes associated with the development of cisplatin resistance

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Sequence Variant Discovery in DNA Repair Genes from Radiosensitive and Radiotolerant Prostate Brachytherapy Patients

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Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer

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Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells

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msh2 Separation of Function Mutations Confer Defects in the Initiation Steps of Mismatch Repair

Kijas, A. W., Studamire, B., & Alani, E. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00694-6 · Cited by 43

Chromosomal mutagen sensitivity associated with mutations in BRCA genes

Speit, G., & Trenz, K. (2004) · Cytogenetic and Genome Research · doi:10.1159/000077511 · Cited by 43

DNA Damage Processing Defects and Disease

Moses, R. E. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.41 · Cited by 43

Targeting DNA mismatch repair for radiosensitization

Berry, S. E., & Kinsella, T. J. (2001) · Seminars in Radiation Oncology · doi:10.1053/s1053-4296(01)80067-9 · Cited by 43

hSnm1 Colocalizes and Physically Associates with 53BP1 before and after DNA Damage

Richie, C. T., Peterson, C. A., Lu, T., Hittelman, W. N., Carpenter, P. B., & Legerski, R. J. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.24.8635-8647.2002 · Cited by 44

TP53, hChk2, and the Li-Fraumeni Syndrome

Varley, J. M. (2003) · Humana Press eBooks · doi:10.1385/1-59259-328-3:117 · Cited by 43

Characterization of a Novel Trans-Activation Domain of BRCA1 That Functions in Concert with the BRCA1 C-terminal (BRCT) Domain

Hu, Y., Miyake, T., Ye, Q., & Li, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.c000607200 · Cited by 42

BRCA1 modulates ionizing radiation‐induced nuclear focus formation by the replication protein A p34 subunit

Choudhary, S. K., & Li, R. (2002) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10081 · Cited by 42

Caffeine Could Not Efficiently Sensitize Homologous Recombination Repair-Deficient Cells to Ionizing Radiation-Induced Killing

Wang, H., Wang, X., Iliakis, G. E., & Wang, Y. (2003) · Radiation Research · doi:10.1667/0033-7587(2003)159[0420:ccnesh]2.0.co;2 · Cited by 42

Characterization of breast cancer by array comparative genomic hybridizationThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.

Climent, J., Garcı́a, J. L., Mao, J., Arsuaga, J., & Pérez‐Losada, J. (2007) · Biochemistry and Cell Biology · doi:10.1139/o07-072 · Cited by 41

A yeast recombination assay to characterize humanBRCA1missense variants of unknown pathological significance

Caligo, M. A., Bonatti, F., Guidugli, L., Aretini, P., & Galli, A. (2008) · Human Mutation · doi:10.1002/humu.20817 · Cited by 41

Molecular Pathogenesis of Fanconi Anemia

Taniguchi, T., & D’Andrea, A. D. (2002) · International Journal of Hematology · doi:10.1007/bf02982016 · Cited by 42

MSH2 and MSH6 in Mismatch Repair System Account for Soybean ( Glycine max (L.) Merr.) Tolerance to Cadmium Toxicity by Determining DNA Damage Response

Zhao, Q., Wang, H., Du, Y., Rogers, H. J., Wu, Z., Jia, S., Yao, X., Xie, F., & Liu, W. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b06599 · Cited by 40

Compromised repair of clustered DNA damage in the human acute lymphoblastic leukemia MSH2-deficient NALM-6 cells

Holt, S. M., Scemama, J., Panayiotidis, M. I., & Georgakilas, A. G. (2008) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2008.09.014 · Cited by 40

Genetic effects of anorganic bovine bone (Bio-Oss®) on osteoblast-like MG63 cells

Carinci, F., Piattelli, A., Degidi, M., Palmieri, A., Perrotti, V., Scapoli, L., Martinelli, M., Laino, G., & Pezzetti, F. (2005) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2005.06.006 · Cited by 40

Human diseases deficient in RecQ helicases

Harrigan, J. A. (2003) · Biochimie · doi:10.1016/j.biochi.2003.10.006 · Cited by 40

The Bloom's Syndrome Helicase Is Critical for Development and Function of the α β T-Cell Lineage

Babbe, H., Chester, N., Leder, P., & Reizis, B. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01402-06 · Cited by 40

Characterisation of the BRCT Domains of the Breast Cancer Susceptibility Gene Product BRCA1

Ekblad, C., Wilkinson, H. R., Schymkowitz, J. W. H., Rousseau, F., Freund, S. M. V., & Itzhaki, L. S. (2002) · Journal of Molecular Biology · doi:10.1016/s0022-2836(02)00478-3 · Cited by 40

RecQ helicases and cellular responses to DNA damage

Wu, L., & Hickson, I. D. (2002) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(02)00225-7 · Cited by 40

The function of Xenopus Bloom's syndrome protein homolog (xBLM) in DNA replicationPreprint

Liao, S., Graham, J., & Yan, H. (2000) · Genes & Development · doi:10.1101/gad.822400 · Cited by 40

Tip60 Is Required for DNA Interstrand Cross-link Repair in the Fanconi Anemia Pathway

Hejna, J., Holtorf, M. L., Hines, J., Mathewson, L., Hemphill, A., Al-Dhalimy, M., Olson, S. B., & Moses, R. E. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709076200 · Cited by 39

MutY and MutY homologs (MYH) in genome maintenance

Lu, A.-L. (2006) · Frontiers in bioscience · doi:10.2741/2033 · Cited by 39

Association between the NBS1E185Q polymorphism and cancer risk: a meta-analysis

Lü, M., Lü, J., Yang, X., Yang, M., Tan, H., Yun, B., & Shi, L. (2009) · BMC Cancer · doi:10.1186/1471-2407-9-124 · Cited by 39

Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population

Loizidou, M. A., Cariolou, M. A., Neuhausen, S. L., Newbold, R. F., Bashiardes, E., Marcou, Y., Michael, T., Daniel, M., Kakouri, E., Papadopoulos, P., et al. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-009-0518-7 · Cited by 39

Molecular biology of Fanconi anaemia—an old problem, a new insight

Ahmad, S., Hanaoka, F., & Kirk, S. H. (2002) · BioEssays · doi:10.1002/bies.10082 · Cited by 39

BRCA1 and BRCA2 in hereditary breast cancer

Scully, R., & Puget, N. (2002) · Biochimie · doi:10.1016/s0300-9084(01)01359-1 · Cited by 46

Brostallicin (PNU-166196) – a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells

Fedier, A., Fowst, C., Tursi, J. M., Geroni, C., Haller, U., Marchini, S., & Fink, D. A. (2003) · British Journal of Cancer · doi:10.1038/sj.bjc.6601316 · Cited by 39

Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells

Siddique, M. A., Nakanishi, K., Taniguchi, T., Grompe, M., & D’Andrea, A. D. (2001) · Experimental Hematology · doi:10.1016/s0301-472x(01)00754-8 · Cited by 39

Nucleotide excision repair “a legacy of creativity”

Cleaver, J. E., Karplus, K. J., Kashani–Sabet, M., & Limoli, C. L. (2001) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(00)00073-2 · Cited by 39

FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice

Sun, X., Brieño‐Enríquez, M. A., Cornelius, A. J., Modzelewski, A. J., Maley, T. T., Campbell-Peterson, K. M., Holloway, J. K., & Cohen, P. E. (2015) · Chromosoma · doi:10.1007/s00412-015-0549-2 · Cited by 40

MutS Homologues hMSH4 and hMSH5: Genetic Variations, Functions, and Implications in Human Diseases

Clark, N. C., Wu, X., & Her, C. (2013) · Current Genomics · doi:10.2174/1389202911314020002 · Cited by 38

Rare Copy Number Variants Observed in Hereditary Breast Cancer Cases Disrupt Genes in Estrogen Signaling and TP53 Tumor Suppression Network

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Strong Correlation of Indoleamine 2,3-Dioxygenase 1 Expression with Basal-Like Phenotype and Increased Lymphocytic Infiltration in Triple-Negative Breast Cancer

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