BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

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Lessons from hereditary colorectal cancer

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A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

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Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

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Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

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Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

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The Bloom's syndrome gene product is homologous to RecQ helicases

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BRCA1 mutations in primary breast and ovarian carcinomas.

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Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase

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Regulation of RelA (p65) Function by the Large Subunit of Replication Factor C

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Cancer Pharmacogenomics

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Functional Interaction Between BRCA1 and DNA Repair in Yeast May Uncover a Role of RAD50, RAD51, MRE11A, and MSH6 Somatic Variants in Cancer Development

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BRCA2 Germline Mutations Identify Gastric Cancers Responsive to PARP Inhibitors

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The regulation of CHK2 in human cancer

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Genetic and cellular mechanisms in chromium and nickel carcinogenesis considering epidemiologic findings

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The function of RecQ helicase gene family (especially BLM) in DNA recombination and joining

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Proteomics of Mouse BRCA1-deficient Mammary Tumors Identifies DNA Repair Proteins with Potential Diagnostic and Prognostic Value in Human Breast Cancer

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Mutational and expressional analysis of RFC3, a clamp loader in DNA replication, in gastric and colorectal cancers

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Twists and turns in the function of DNA damage signaling and repair proteins by post-translational modifications

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Recombination: Mechanisms and Roles in Tumorigenesis

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Homologous Recombination Repair Gene Mutations in Prostate Cancer: Prevalence and Clinical Value

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Biomarkers in high grade serous ovarian cancer

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ATM and Cellular Response to DNA Damage

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Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1

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Suppression of BRCA1 sensitizes cells to proteasome inhibitors

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DNA Damage Response Mediated through BRCA1

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BRCA1/2 genetic background-based therapeutic tailoring of human ovarian cancer: hope or reality?

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A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation

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Inherited aplastic anaemia

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Small Molecule Modulation of the Human Chromatid Decatenation Checkpoint

Haggarty, S. J., Koeller, K. M., Kau, T. R., Silver, P. A., Roberge, M., & Schreiber, S. L. (2003) · Chemistry & Biology · doi:10.1016/j.chembiol.2003.11.014 · Cited by 24

Yra1 Is Required for S Phase Entry and Affects Dia2 Binding to Replication Origins

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Complex-based analysis of dysregulated cellular processes in cancer

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Sen1p Contributes to Genomic Integrity by Regulating Expression of Ribonucleotide Reductase 1 (RNR1) in Saccharomyces cerevisiae

Golla, U., Singh, V., Azad, G. K., Singh, P. K., Verma, N., Mandal, P., Chauhan, S., & Tomar, R. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064798 · Cited by 23

Mechanisms used by DNA MMR system to cope with Cadmium-induced DNA damage in plants

Wang, H., Cao, Q., Zhao, Q., Arfan, M., & Liu, W. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.125614 · Cited by 23

DNA Damage and Polyploidization

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N-Methyl-N′-nitro-N-nitrosoguanidine (MNNG) Triggers MSH2 and Cdt2 Protein-dependent Degradation of the Cell Cycle and Mismatch Repair (MMR) Inhibitor Protein p21Waf1/Cip1

Jascur, T. A., Fotedar, R., Greene, S., Hotchkiss, E. C., & Boland, C. R. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.221341 · Cited by 23

The chromatin remodeling protein BRG1 modulates BRCA1 response to UV irradiation by regulating ATR/ATM activation

Zhang, L., Chen, H., Gong, M., & Gong, F. (2013) · Frontiers in Oncology · doi:10.3389/fonc.2013.00007 · Cited by 24

Chromosome Breakage Is Regulated by the Interaction of the BLM Helicase and Topoisomerase IIα

Russell, B., Bhattacharyya, S., Keirsey, J. K., Sandy, A., Grierson, P. M., Perchiniak, E. M., Kavecansky, J., Acharya, S., & Groden, J. L. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-1727 · Cited by 23

Mutation analysis of multiple pilomatricomas in a patient with myotonic dystrophy type 1 suggests a DM1-associated hypermutation phenotype

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Pharmacogenomics in lung cancer: an analysis of DNA repair gene expression in patients treated with platinum-based chemotherapy

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Development of therapeutic approaches to ‘triple negative’ phenotype breast cancer

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Mapping and conformational characterization of the DNA-binding region of the breast cancer susceptibility protein BRCA1

Naseem, R., Sturdy, A., Finch, D., Jowitt, T. A., & Webb, M. (2006) · Biochemical Journal · doi:10.1042/bj20051646 · Cited by 23

RecQ helicases and genome stability: lessons from model organisms and human disease

Bjergbæk, L., Cobb, J., & Gasser, S. M. (2002) · Swiss Medical Weekly · doi:10.4414/smw.2002.09886 · Cited by 23

Deoxycholate, an Endogenous Tumor Promoter and DNA Damaging Agent, Modulates BRCA-1 Expression in Apoptosis-Sensitive Epithelial Cells: Loss of BRCA-1 Expression in Colonic Adenocarcinomas

Romagnolo, D. F., Chirnomas, R. B., Ku, J., Jeffy, B. D., Payne, C. M., Holubec, H., Ramsey, L., Bernstein, H., Bernstein, C., Kunke, K., et al. (2003) · Nutrition and Cancer · doi:10.1207/s15327914nc4601_11 · Cited by 23

Efficient Incorporation of Large (>2 kb) Heterologies Into Heteroduplex DNA: Pms1/Msh2-Dependent and -Independent Large Loop Mismatch Repair in Saccharomyces cerevisiae

Clikeman, J. A., Wheeler, S. L., & Nickoloff, J. A. (2001) · Genetics · doi:10.1093/genetics/157.4.1481 · Cited by 23

Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombinationPreprint

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Structural basis to characterise transactivation domain of BRCA1

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Impact of Physical Activity on Oxidative Stress Markers in Patients with Metastatic Breast Cancer

Delrieu, L., Touillaud, M. S., Pérol, O., Morelle, M., Martin, A., Friedenreich, C. M., Mury, P., Dufresne, A., Bachelot, T., Heudel, P., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/6694594 · Cited by 22

BLM and RAD51 Genes Polymorphism and Susceptibility to Breast Cancer

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Genome-wide differential gene expression in immortalized DF-1 chicken embryo fibroblast cell line

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The Foci of DNA Double Strand Break-recognition Proteins Localize with γH2AX after Heat Treatment

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Radiosensitivity of lymphoblastoid cell lines with a heterozygous BRCA1 mutation is not detected by the comet assay and pulsed field gel electrophoresis

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Turnover of BRCA1 Involves in Radiation-Induced Apoptosis

Liu, W., Zong, W., Wu, G. Y., Fujita, T., Li, W., Wu, J. Q., & Wan, Y. (2010) · PLoS ONE · doi:10.1371/journal.pone.0014484 · Cited by 24

Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells

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Repair bias of large loop mismatches during recombination in mammalian cells depends on loop length and structure

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Independence of R/M/N Focus Formation and the Presence of Intact BRCA1

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Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis

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R-loop modulated epigenetic regulation in T helper cells mechanistically associates coronary artery disease and non-small cell lung cancer

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Expression of base excision repair key factors and miR17 in familial and sporadic breast cancer

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ATM gene mutations in sporadic breast cancer patients from Brazil

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Fanconi Anemia Pathway in Colorectal Cancer: A Novel Opportunity for Diagnosis, Prognosis and Therapy

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BRCA1 knock-down causes telomere dysfunction in mammary epithelial cells

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The role of chromatin proteins in DNA damage recognition and repair Mini-review

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Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes

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Expression of the Mismatch Repair Gene hMLH1 Is Enhanced in Non-Small Cell Lung Cancer with EGFR Mutations

Li, M., Zhang, Q., Liu, L., Lu, W., Wei, H., Li, R., & Shen, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078500 · Cited by 20

An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer

Daniela Gerovska, D., Larrinaga, G., Solano-Iturri, J. D., Márquez, J., García-Gallastegui, P., Khatib, A., Poschmann, G., Stühler, K., Armesto, M., Lawrie, C. H., et al. (2020) · Cancers · doi:10.3390/cancers12092380 · Cited by 20

Nuclear antiviral innate responses at the intersection of DNA sensing and DNA repair

Justice, J. L., & Cristea, I. M. (2022) · Trends in Microbiology · doi:10.1016/j.tim.2022.05.004 · Cited by 21

Lympho-vascular invasion in BRCA related breast cancer compared to sporadic controls

van Voss, M. R. H., van der Groep, P., Bart, J., van der Wall, E., & van Diest, P. J. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-145 · Cited by 20

An Interstitial Deletion at 3p21.3 Results in the Genetic Fusion ofMLH1andITGA9in a Lynch Syndrome Family

Meyer, C., Brieger, A., Plotz, G., Weber, N., Passmann, S., Dingermann, T., Zeuzem, S., Trojan, J., & Marschalek, R. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-1908 · Cited by 20

Blocking protein quality control to counter hereditary cancers

Kampmeyer, C., Nielsen, S. V., Clausen, L., Stein, A., Gerdes, A., Lindorff‐Larsen, K., & Hartmann‐Petersen, R. (2017) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22487 · Cited by 21

Expression profiles and intergenic structure of head-to-head oriented Brca1 and Nbr1 genes

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BRCA1 interactors, RAD50 and BRIP1, as prognostic markers for triple-negative breast cancer severity

Laha, S., Katheeja Muhseena, N., Das, R., & Das, R. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1035052 · Cited by 19

Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and CpG island methylation of tumor suppressor genes

Naushad, S. M., Hussain, T., Al-Attas, O. S., Prayaga, A. K., Digumarti, R., Gottumukkala, S. R., & Kutala, V. K. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2037-z · Cited by 19

Synonymous Constraint Elements Show a Tendency to Encode Intrinsically Disordered Protein Segments

Macossay-Castillo, M., Kosol, S., Tompa, P., & Pancsa, R. (2014) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003607 · Cited by 21

DNA Repair System and Prostate Cancer Progression: The Role of NBS1 Polymorphism (rs1805794)

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Characterizing methylation regulated miRNA in carcinoma of the human uterine cervix

Varghese, V. K., Shukla, V., Jishnu, P. V., Kabekkodu, S. P., Pandey, D., Sharan, K., & Satyamoorthy, K. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.116668 · Cited by 19

Mammalian DNA Damage Response Pathway

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The MRN-CtIP Pathway Is Required for Metaphase Chromosome Alignment

Rozier, L., Guo, Y., Peterson, S., Sato, M., Baer, R. J., Gautier, J., & Mao, Y. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.01.023 · Cited by 19

From NPC Therapeutic Target Identification to Potential Treatment Strategy

Lan, M., Chen, C., Lin, K., Lee, S., Yang, W.-L. R., Hsu, C.-N., Wu, J., Ho, C., Lin, J., & Huang, C. F. (2010) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-09-0966 · Cited by 19

Association of rare MSH6 variants with familial breast cancer

Wasielewski, M., Riaz, M., Vermeulen, J., van den Ouweland, A., Labrijn-Marks, I., Olmer, R., van der Spaa, L., Klijn, J. G. M., Meijers-Heijboer, H. E. J., Dooijes, D., et al. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-009-0634-4 · Cited by 21

Deletions of BRCA1/2 and p53 R248W gain-of-function mutation suggest impaired homologous recombination repair in fragile histidine triad-negative sebaceous gland carcinomas

Becker, K., Goldberg, M., Helmbold, P., Holbach, L., Loeffler, K. U., & Ballhausen, W. G. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08783.x · Cited by 19

ATM's leucine-rich domain and adjacent sequences are essential for ATM to regulate the DNA damage response

Chen, S., Paul, P., & Price, B. D. (2003) · Oncogene · doi:10.1038/sj.onc.1206760 · Cited by 19

The Large Subunit of Replication Factor C Interacts with the Histone Deacetylase, HDAC1

Anderson, L. A., & Perkins, N. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200513200 · Cited by 19

Multiple roles for MSH2 in the repair of a deletion mutation directed by modified single-stranded oligonucleotides

Maguire, K., & Kmiec, E. B. (2006) · Gene · doi:10.1016/j.gene.2006.08.014 · Cited by 19

Impaired Skin and Mammary Gland Development and Increased γ-Irradiation–Induced Tumorigenesis in Mice Carrying a Mutation of S1152-ATM Phosphorylation Site in Brca1

Kim, S. S., Cao, L., Baek, H. J., Lim, S., Li, C., Wang, R., Xu, X., Cho, K. H., & Deng, C. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-2418 · Cited by 20

BRCA1 is required for hMLH1 stabilization following doxorubicin-induced DNA damage

Romeo, F., Falbo, L., Di Sanzo, M., Misaggi, R., Faniello, M. C., Viglietto, G., Cuda, G., Costanzo, F., & Quaresima, B. (2011) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2011.08.011 · Cited by 18

Ataxia telangiectasia mutated‐dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor

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Genetic Variants of NBS1 Predict Clinical Outcome of Platinum-based Chemotherapy in Advanced Non-small Cell Lung Cancer in Chinese

Xu, J., Hu, L., Huang, M., Zhao, W., Yin, Y., Hu, Z., Ma, H., Shen, H., & Shu, Y. (2012) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2012.13.3.851 · Cited by 18

Ring chromosomes: vicious circles at the end and beginning of life

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MutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repair

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Functional interactions between BLM and XRCC3 in the cell

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Expression of BRCA1, NBR1 and NBR2 Genes in Human Breast Cancer Cells

Dimitrov, S. D., Matoušková, E., & Forejt, J. (2001) · Folia Biologica · doi:10.14712/fb2001047040120 · Cited by 18

Degradation of ATM-Independent Decatenation Checkpoint Function in Human Cells is Secondary to Inactivation of p53 and Correlated with Chromosomal Destabilization

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Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

Hughes, D. J. (2008) · Familial Cancer · doi:10.1007/s10689-008-9181-0 · Cited by 18

Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome

Ouyang, Y., Salstrom, J. L., Diaz-Perez, S. V., Nahas, S., Matsuno, Y., Dawson, D. W., Teitell, M. A., Horvath, S., Riggs, A. D., Gatti, R. A., et al. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.09.122 · Cited by 19

Roles of RecQ Family Helicases in the Maintenance of Genome StabilityPreprint

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BLM protein mitigates formaldehyde-induced genomic instability

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Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors

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The germline variants in DNA repair genes in pediatric medulloblastoma: a challenge for current therapeutic strategies

Trubicka, J., Żemojtel, T., Hecht, J., Falana, K., Piekutowska‐Abramczuk, D., Płoski, R., Perek‐Polnik, M., Drogosiewicz, M., Grajkowska, W., Ciara, E., et al. (2017) · BMC Cancer · doi:10.1186/s12885-017-3211-y · Cited by 17

Cell biology of cancer: BRCA1 and sister chromatid pairing reactions?

Skibbens, R. V. (2008) · Cell Cycle · doi:10.4161/cc.7.4.5435 · Cited by 17

DNA Double Strand Break Repair and its Association with Inherited Predispositions to Breast Cancer

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BRCA1 carries tumor suppressor activity distinct from that of p53 and p21

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Molecular Inhibitors of DNA Repair: Searching for the Ultimate Tumor Killing Weapon

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Chromosome Instability in Patients with Chronic Renal Failure

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Analysis of the molecular mechanism of osteosarcoma using a bioinformatics approach

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BASC (BRCA1‐associated genome surveillance complex)

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Coordination of BRCA1/BARD1- and MRE11/RAD50/NBS1-dependent DNA Transactions in Breast Tumor Suppression

Gautier, J., & Greene, E. C. (2009) · doi:10.21236/ada519536

Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage

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Evaluation of BRCA1 related DNA repair genes in breast and ovarian carcinogenesis

MARESCA, L. (2017) · Electronic Theses and Dissertations Repository (University of Pisa)