BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

Miki, Y., Swensen, J. J., Shattuck-Eidens, D. M., Futreal, P. A., Harshman, K., Tavtigian, S. V., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., et al. (1994) · Science · doi:10.1126/science.7545954 · Cited by 6,069

Lessons from hereditary colorectal cancer

Kinzler, K. W., & Vogelstein, B. (1996) · Cell · doi:10.1016/s0092-8674(00)81333-1 · Cited by 4,919

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., et al. (1995) · Science · doi:10.1126/science.7792600 · Cited by 2,785

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Canman, C. E., Lim, D.-S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., & Siliciano, J. D. (1998) · Science · doi:10.1126/science.281.5383.1677 · Cited by 2,042

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

Banin, S., Moyal, L., Shieh, S.-Y., Taya, Y., Anderson, C. W., Chessa, L., Smorodinsky, N. I., Prives, C., Reiss, Y., Shiloh, Y., et al. (1998) · Science · doi:10.1126/science.281.5383.1674 · Cited by 1,797

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T., & Livingston, D. M. (1997) · Cell · doi:10.1016/s0092-8674(00)81847-4 · Cited by 1,459

The Bloom's syndrome gene product is homologous to RecQ helicases

Ellis, N. A., Groden, J. L., Ye, T.-Z., Straughen, J. E., Lennon, D. J., Ciocci, S., Proytcheva, M. A., & GERMAN, J. L. (1995) · Cell · doi:10.1016/0092-8674(95)90105-1 · Cited by 1,385

BRCA1 mutations in primary breast and ovarian carcinomas.

Futreal, P., Liu, Q., Shattuck-Eidens, D., Cochran, C., Harshman, K., Tavtigian, S., Bennett, L., Haugen-Strano, A., Swensen, J., & Miki, Y. (1994) · Science · doi:10.1126/science.7939630 · Cited by 1,378

Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase

Matsuoka, S. (1998) · Science · doi:10.1126/science.282.5395.1893 · Cited by 1,322

Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells

Rassool, F. V., North, P. S., Mufti, G. J., & Hickson, I. D. (2003) · Oncogene · doi:10.1038/sj.onc.1206970 · Cited by 37

BRCA1 is a novel regulator of metabolic function in skeletal muscle

Jackson, K. C., Gidlund, E., Norrbom, J., Valencia, A. P., Thomson, D. M., Schuh, R. A., Neufer, P. D., & Spangenburg, E. E. (2014) · Journal of Lipid Research · doi:10.1194/jlr.m043851 · Cited by 38

Proteolysis of the Mismatch Repair Protein MLH1 by Caspase-3 Promotes DNA Damage-induced Apoptosis

Chen, F., Arseven, O. K., & Cryns, V. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400971200 · Cited by 37

Interplay between Drosophila Bloom's syndrome helicase and Ku autoantigen during nonhomologous end joining repair of P element-induced DNA breaks

Min, B., Weinert, B. T., & Rio, D. C. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403000101 · Cited by 37

An Activation Force-based Affinity Measure for Analyzing Complex Networks

Guo, J. H., Guo, H., & Wang, Z. (2011) · Scientific Reports · doi:10.1038/srep00113 · Cited by 36

A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function

Kononenko, A. V., Bansal, R., Lee, N., Grimes, B. R., Masumoto, H., Earnshaw, W. C., Larionov, V., & Kouprina, N. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku870 · Cited by 36

Inferring Novel Tumor Suppressor Genes with a Protein-Protein Interaction Network and Network Diffusion Algorithms

Chen, L., Zhang, Y., Zhang, Z., Huang, T., & Cai, Y. (2018) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2018.06.007 · Cited by 36

Understanding Germ-Line Mutations inBRCA1

Szabo, C. I., Worley, T., & Monteiro, Á. N. A. (2004) · Cancer Biology & Therapy · doi:10.4161/cbt.3.6.841 · Cited by 37

p53 Monitors Replication Fork Regression by Binding to “Chickenfoot” Intermediates

Subramanian, D., & Griffith, J. D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506348200 · Cited by 36

Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells

Acharya, S. K., Kaul, Z., Gocha, A. R. S., Martinez, A. R., Harris, J. M., Parvin, J. D., & Groden, J. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103819 · Cited by 40

Modification of Ovarian Cancer Risk by BRCA1/2 -Interacting Genes in a Multicenter Cohort of BRCA1/2 Mutation Carriers

Rebbeck, T. R., Mitra, N., Domchek, S. M., Wan, F., Chuai, S., Friebel, T. M., Panossian, S., Spurdle, A. B., Chenevix‐Trench, G., kConFab, et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0625 · Cited by 36

The ubiquitin‐proteasome system in cancer, a major player in DNA repair. Part 1: post‐translational regulation

Vlachostergios, P. J., Patrikidou, A., Daliani, D., & Papandreou, C. N. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00824.x · Cited by 36

Dephosphorylation and Subcellular Compartment Change of the Mitotic Bloom's Syndrome DNA Helicase in Response to Ionizing Radiation

Dutertre, S., Sekhri, R., Tintignac, L. A. J., Onclercq, R., Chatton, B., Jaulin, C., & Amor-Guéret, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m105735200 · Cited by 36

BRCA1 and Transcription

Lane, T. F. (2004) · Cancer Biology & Therapy · doi:10.4161/cbt.3.6.843 · Cited by 36

Dimerization of the ATRIP Protein through the Coiled-Coil Motif and Its Implication to the Maintenance of Stalled Replication Forks

Itakura, E., Sawada, I., & Matsuura, A. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-05-0427 · Cited by 35

Polymorphisms in hMLH1 and risk of early-onset lung cancer in a southeast Chinese population

An, Y., Jin, G., Wang, H., Wang, Y., Liu, H., Li, R., Wang, H., Qian, J., Sun, W., Wang, Y., et al. (2007) · Lung Cancer · doi:10.1016/j.lungcan.2007.08.003 · Cited by 35

The Role of Ku70 as a Cytosolic DNA Sensor in Innate Immunity and Beyond

Sui, H., Hao, M., Chang, W., & Imamichi, T. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.761983 · Cited by 36

Modulation of error-prone double-strand break repair in mammalian chromosomes by DNA mismatch repair protein Mlh1

Bannister, L., Waldman, B. C., & Waldman, A. S. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.01.001 · Cited by 36

Chlamydomonas reinhardtii: a convenient model system for the study of DNA repair in photoautotrophic eukaryotes

Vlček, D., Ševčovičová, A., Sviežená, B., Gálová, E., & Miadoková, E. (2007) · Current Genetics · doi:10.1007/s00294-007-0163-9 · Cited by 35

Unwinding protein complexes in ALTernative telomere maintenance

Bhattacharyya, S., Sandy, A., & Groden, J. L. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22388 · Cited by 37

Dysregulation of DNA Repair Pathways in a Transforming Growth Factor α/c-myc Transgenic Mouse Model of Accelerated Hepatocarcinogenesis

Hironaka, K., Factor, V. M., Calvisi, D. F., Conner, E. A., & Thorgeirsson, S. S. (2003) · Laboratory Investigation · doi:10.1097/01.lab.0000067483.89649.11 · Cited by 35

Scientists and clinicians test their metal–back to the future with platinum compounds

Guminski, A. D., Harnett, P. R., & DeFazio, A. (2002) · The Lancet Oncology · doi:10.1016/s1470-2045(02)00733-7 · Cited by 34

Lynch-like Syndrome: Potential Mechanisms and Management

Martínez‐Roca, A., Giner-Calabuig, M., Murcia, Ó., Castillejo, A., Soto, J. L., García‐Heredia, A., & Jover, R. (2022) · Cancers · doi:10.3390/cancers14051115 · Cited by 35

Clique-based data mining for related genes in a biomedical database

Matsunaga, T., Yonemori, C., Tomita, E., & Muramatsu, M. (2009) · BMC Bioinformatics · doi:10.1186/1471-2105-10-205 · Cited by 34

Oncodrive-CIS: A Method to Reveal Likely Driver Genes Based on the Impact of Their Copy Number Changes on Expression

Tamborero, D., López-Bigas, N., & González-Pérez, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055489 · Cited by 34

BRCA1 Contributes to Cell Cycle Arrest and Chemoresistance in Response to the Anticancer Agent Irofulven

Wiltshire, T. D., Senft, J., Wang, Y., Konat, G. W., Wenger, S. L., Reed, E., & Wang, W. (2007) · Molecular Pharmacology · doi:10.1124/mol.106.029504 · Cited by 34

BRCA1—A good predictive marker of drug sensitivity in breast cancer treatment?

Mullan, P. B., Gorski, J. J., & Harkin, D. P. (2006) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2006.07.001 · Cited by 34

Evidence that dysregulated DNA mismatch repair characterizes human nonmelanoma skin cancer

Young, L. C., Listgarten, J., Trotter, M. J., Andrew, S. E., & Tron, V. A. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2007.08249.x · Cited by 34

Different genetic pathways in the development of periocular sebaceous gland carcinomas in presumptive Muir-Torre syndrome patients

Goldberg, M., Rummelt, C., Foja, S., Holbach, L., & Ballhausen, W. G. (2006) · Human Mutation · doi:10.1002/humu.20281 · Cited by 34

Down-Regulation of BRCA1 in Chronic Pancreatitis and Sporadic Pancreatic Adenocarcinoma

Beger, C., Ramadani, M., Meyer, S., Leder, G. H., Krüger, M., Welte, K., Gansauge, F., & Beger, H. G. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-0992-3 · Cited by 34

Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers

Santarosa, M., Col, L. D., Tonin, E., Caragnano, A., Viel, A., & Maestro, R. (2009) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-08-0951 · Cited by 33

A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

Beard, P. M., Griffiths, S. J., Gonzalez, O., Haga, I. R., Jowers, T. P., Reynolds, D. K., Wildenhain, J., Tekotte, H., Auer, M., Tyers, M., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098431 · Cited by 33

Mechanism and significance of chromosome damage repair by homologous recombination

Kawale, A. S., & Sung, P. (2020) · Essays in Biochemistry · doi:10.1042/ebc20190093 · Cited by 33

BRCA1 modulates the expression of hnRNPA2B1 and KHSRP

Santarosa, M., Col, L. D., Viel, A., Bivi, N., DˈAmbrosio, C., Scaloni, A., Tell, G., & Maestro, R. (2010) · Cell Cycle · doi:10.4161/cc.9.23.14022 · Cited by 33

Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1

Her, C. (2002) · DNA repair · doi:10.1016/s1568-7864(02)00079-4 · Cited by 33

Novel consensus DNA‐binding sequence for BRCA1 protein complexes

Cable, P., Wilson, C., Calzone, F. J., Rauscher, F. J., Scully, R., Livingston, D. M., Li, L., Blackwell, C. B., Futreal, P. A., & Afshari, C. A. (2003) · Molecular Carcinogenesis · doi:10.1002/mc.10148 · Cited by 33

A Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences inSaccharomyces cerevisiae

Chakraborty, U., George, C. M., Lyndaker, A. M., & Alani, E. (2015) · Genetics · doi:10.1534/genetics.115.184093 · Cited by 33

ATM in breast and brain tumors: a comprehensive review

Mehrdad, A. E., & Mehdipour, P. (2018) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2018.0022 · Cited by 34

Constitutive mRNA expression of DNA repair-related genes as a biomarker for clinical radio-resistance: A pilot study in prostate cancer patients receiving radiotherapy

Hümmerich, J., Werle‐Schneider, G., Popanda, O., Celebi, O., Chang-Claude, J., Kropp, S., Mayer, C., Debus, J., Bartsch, H., & Schmezer, P. (2006) · International Journal of Radiation Biology · doi:10.1080/09553000600883302 · Cited by 33

BRCA1 Activates a G2-M Cell Cycle Checkpoint following 6-Thioguanine–Induced DNA Mismatch Damage

Yamane, K., Schupp, J. E., & Kinsella, T. J. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-2205 · Cited by 33

HDAC Inhibitors: A New Radiosensitizer for Non-small-cell Lung Cancer

Zhu, L., Wu, K., Ma, S., & Zhang, S. (2015) · Tumori Journal · doi:10.5301/tj.5000347 · Cited by 32

BRCA1 and BRCA2 Gene Expression: Diurnal Variability and Influence of Shift Work

Bracci, M., Ciarapica, V., Elexpuru-Zabaleta, M., Tartaglione, M. F., Pirozzi, S., Giuliani, L., Piva, F., Valentino, M., Ledda, C., Rapisarda, V., et al. (2019) · Cancers · doi:10.3390/cancers11081146 · Cited by 32

Rb-Associated Protein 46 (RbAp46) Inhibits Transcriptional Transactivation Mediated by BRCA1

Chen, G.-C., Guan, L., Yu, J., Li, G., Kim, H.-R. C., & Wang, Z. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5003 · Cited by 32

Isoflavones are safe compounds for therapeutical applications – Evaluation ofin vitrodata

Reiter, E., Reiter, E., Beck, V., Medjakovic, S., & Jungbauer, A. (2009) · Gynecological Endocrinology · doi:10.1080/09513590802596461 · Cited by 32

Immunoassay-based proteome profiling of 24 pancreatic cancer cell lines

Alhamdani, M. S. S., Youns, M., Buchholz, M., Gress, T. M., Beckers, M., Maréchal, D., Bauer, A. S., Schröder, C., & Hoheisel, J. D. (2012) · Journal of Proteomics · doi:10.1016/j.jprot.2012.04.042 · Cited by 34

Werner syndrome protein, the MRE11 complex and ATR: menage‐à‐trois in guarding genome stability during DNA replication?

Pichierri, P., & Franchitto, A. (2004) · BioEssays · doi:10.1002/bies.10411 · Cited by 32

ALPK2 is crucial for luminal apoptosis and DNA repair-related gene expression in a three-dimensional colonic-crypt model.

Yoshida, Y., Tsunoda, T., Doi, K., Fujimoto, T., Tanaka, Y., Ota, T., Ogawa, M., Matsuzaki, H., Kuroki, M., Iwasaki, A., et al. (2012) · PubMed · Cited by 32

Mismatch Repair Polymorphisms as Markers of Breast Cancer Prevalence in the Breast Cancer Family Registry

Deyssenroth, M. A., Terry, M. B., Delgado‐Cruzata, L., Liao, Y., & Santella, R. M. (2016) · Anticancer Research · doi:10.21873/anticanres.10987 · Cited by 32

Powerful tools for the characterization of protein complexes

Bauer, A., & Küster, B. (2003) · Cited by 32

Molecular biology and genetics of breast cancer development: A clinical perspective

Buchholz, T. A., & Wazer, D. E. (2002) · Seminars in Radiation Oncology · doi:10.1053/srao.2002.35248 · Cited by 32

Gene expression in the mouse preimplantation embryo

Stanton, J. L., Macgregor, A. B., & Green, D. P. L. (2003) · Reproduction · doi:10.1530/rep.0.1250457 · Cited by 32

Deficiency in SNM1 Abolishes an Early Mitotic Checkpoint Induced by Spindle Stress

Akhter, S., Richie, C. T., Deng, J. M., Brey, E. M., Zhang, X., Patrick, C., Behringer, R. R., & Legerski, R. J. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.23.10448-10455.2004 · Cited by 32

Deficient Regulation of DNA Double-strand Break Repair in Fanconi Anemia Fibroblasts

Donahue, S. L., Lundberg, R., Saplis, R., & Campbell, C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m213251200 · Cited by 32

Immune Checkpoint Blockade in Breast Cancer Therapy

Bu, X., Yao, Y., & Li, X. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-6020-5_18 · Cited by 31

A Role for DNA Mismatch Repair Protein Msh2 in Error-Prone Double-Strand-Break Repair in Mammalian Chromosomes

Smith, J. A., Waldman, B. C., & Waldman, A. S. (2005) · Genetics · doi:10.1534/genetics.104.039362 · Cited by 32

Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction

Bennett, C. B., Westmoreland, T. J., Verrier, C. S., Blanchette, C., Winsor, T. S., Phatnani, H. P., Mishina, Y. V., Hüper, G., Selim, A. L., Madison, E. R., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001448 · Cited by 33

High-throughput fluorescence polarization assay to identify small molecule inhibitors of BRCT domains of breast cancer gene 1

Lokesh, G. L.-R., Rachamallu, A., Kumar, G. D. K., & Natarajan, A. (2006) · Analytical Biochemistry · doi:10.1016/j.ab.2006.01.025 · Cited by 32

WRN Loss Induces Switching of Telomerase-Independent Mechanisms of Telomere Elongation

Gocha, A. R. S., Acharya, S., & Groden, J. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093991 · Cited by 32

Deregulated estrogen receptor signaling and DNA damage response in breast tumorigenesis

Rajan, A., Nadhan, R., Latha, N. R., Krishnan, N., Warrier, A. V., & Srinivas, P. (2020) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2020.188482 · Cited by 30

BRCA1 deficiency in triple-negative breast cancer: Protein stability as a basis for therapy

Choi, E. A., Mun, G., Lee, J., Lee, H., Cho, J., & Lee, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114090 · Cited by 34

Cancer cell-specific cGAS/STING Signaling pathway in the era of advancing cancer cell biology

Kumar, V., Bauer, C., & Stewart, J. H. (2023) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2023.151338 · Cited by 33

Analysis of the ERK1,2 transcriptome in mammary epithelial cells

Grill, C. J., Gheyas, F., Dayananth, P., Jin, W., Ding, W., Ping, Q. I. U., Wang, L., Doll, R. J., & English, J. M. (2004) · Biochemical Journal · doi:10.1042/bj20031688 · Cited by 30

The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors

Winter, S. L., Bosnoyan-Collins, L., Pinnaduwage, D., & Andrulis, I. L. (2007) · BMC Cancer · doi:10.1186/1471-2407-7-85 · Cited by 30

Transcription-coupled repair of oxidative DNA damage in human cells: \nMechanisms and consequences

Tsutakawa, S. E., & Cooper, P. K. (2001) · eScholarship (California Digital Library) · Cited by 31

Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair

Cantor, S. B., & Xie, J. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20568 · Cited by 29

NBN Gene Polymorphisms and Cancer Susceptibility: A Systemic Review

Berardinelli, F., di Masi, A., & Antoccia, A. (2013) · Current Genomics · doi:10.2174/13892029113146660012 · Cited by 30

Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients

Knopf, A., Lempart, J., Baş, M., Slotta‐Huspenina, J., Mansour, N., & Fritsche, M. K. (2015) · Oncotarget · doi:10.18632/oncotarget.2850 · Cited by 29

BRCA1 Forms a Functional Complex with γ ‐H2AX as a Late Response to Genotoxic Stress

Krum, S. A., Dalugdugan, E. D. L. R., Miranda‐Carboni, G. A., & Lane, T. F. (2010) · Journal of Nucleic Acids · doi:10.4061/2010/801594 · Cited by 32

BRCA1: a scaffold for p53 response?

Hohenstein, P., & Giles, R. H. (2003) · Trends in Genetics · doi:10.1016/s0168-9525(03)00193-8 · Cited by 29

Role of c-Abl Kinase in DNA Mismatch Repair-dependent G2 Cell Cycle Checkpoint Arrest Responses

Wagner, M. W., Li, L. S., Morales, J. C., Galindo, C. L., Garner, H. R., Bornmann, W. G., & Boothman, D. A. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709953200 · Cited by 29

The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair

Patidar, P. L., Motea, E. A., Fattah, F. J., Zhou, Y., Morales, J. C., Xie, Y., Garner, H. R., & Boothman, D. A. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkv1492 · Cited by 29

The carboxyl-terminal of BRCA1 is required for subnuclear assembly of RAD51 after treatment with cisplatin but not ionizing radiation in human breast and ovarian cancer cells

Zhou, C., Huang, P., & Liu, J. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.08.197 · Cited by 29

Roads Leading to Breast Cancer

Haber, D. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011233432111 · Cited by 29

ATM in oral carcinogenesis: association with clinicopathological features

He, Y., Chen, Q., & Li, B. (2008) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-008-0365-7 · Cited by 28

A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies

Zhang, Y., Fox, J. T., Park, Y.-U., Elliott, G., Rai, G., Cai, M., Sakamuru, S., Huang, R., Xia, M., Lee, K., et al. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-2974 · Cited by 28

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway

Ando, K., Shah, A. K., Sachdev, V., Kleinstiver, B. P., Taylor‐Parker, J., Welch, M. M., Hu, Y., Salgia, R., White, F. M., Parvin, J. D., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.16376 · Cited by 28

The Fanconi anemia pathway and the DNA interstrand cross-links repair

Rosselli, F. (2003) · Biochimie · doi:10.1016/j.biochi.2003.11.002 · Cited by 28

Structural Studies of DNA End Detection and Resection in Homologous RecombinationPreprint

Schiller, C. B., Seifert, F. U., Linke, C., & Hopfner, K. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a017962 · Cited by 29

Hereditary cancer syndromes: utilizing DNA repair deficiency as therapeutic target

Goyal, G., Fan, T., & Silberstein, P. T. (2016) · Familial Cancer · doi:10.1007/s10689-016-9883-7 · Cited by 28

Triomics Analysis of Imatinib-Treated Myeloma Cells Connects Kinase Inhibition to RNA Processing and Decreased Lipid Biosynthesis

Breitkopf, S. B., Yuan, M., Helenius, K., Lyssiotis, C. A., & Asara, J. M. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b03040 · Cited by 27

Morphological and pathological features of basal-like breast cancer

Botti, G., Cantile, M., Collina, F., Cerrone, M., Sarno, S., Anniciello, A., & Bonito, M. D. (2019) · Translational Cancer Research · doi:10.21037/tcr.2019.06.50 · Cited by 27

Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination

Restle, A., Janz, C., & Wiesmüller, L. (2005) · Oncogene · doi:10.1038/sj.onc.1208639 · Cited by 27

RecQ helicases; at the crossroad of genome replication, repair, and recombination

Rezazadeh, S. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-1243-y · Cited by 28

BRCA1 mutation spectrum, functions, and therapeutic strategies: The story so far

Sharma, B., Kaur, R. P., Raut, S., & Munshi, A. (2018) · Current Problems in Cancer · doi:10.1016/j.currproblcancer.2018.01.001 · Cited by 31

BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor

Priyadarshini, R., Hussain, M., Attri, P., Kaur, E., Tripathi, V., Priya, S., Dhapola, P., Saha, D., Madhavan, V., Chowdhury, S., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.06.101 · Cited by 27

BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation‐induced gene activation of p21 or Mdm2

Hill, D. A., de la Serna, I. L., Veal, T. M., & Imbalzano, A. N. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20003 · Cited by 27

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LEDGF/p75 Is Required for an Efficient DNA Damage Response

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Promising molecular targets in ovarian cancer

Blagden, S. P., & Gabra, H. (2009) · Current Opinion in Oncology · doi:10.1097/cco.0b013e32832eab1f · Cited by 26

Non-Bloom syndrome-associated partial and total loss-of-function variants of BLM helicase

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Alternative recombination pathways in UV-irradiated XP variant cells

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Molecular Pathogenesis of Fanconi Anemia

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ATM allelic variants associated to hereditary breast cancer in 94 Chilean women: susceptibility or ethnic influences?

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DNA mismatch repair efficiency and fidelity are elevated during DNA synthesis in human cells

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BASC (BRCA1‐associated genome surveillance complex)

(2008) · Springer eBooks · doi:10.1007/978-1-4020-6754-9_1584

Coordination of BRCA1/BARD1- and MRE11/RAD50/NBS1-dependent DNA Transactions in Breast Tumor Suppression

Gautier, J., & Greene, E. C. (2009) · doi:10.21236/ada519536

Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage

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MARESCA, L. (2017) · Electronic Theses and Dissertations Repository (University of Pisa)