The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Brain Gene Expression During REM Sleep Depends on Prior Waking Experience
Open accessAbstract
In most mammalian species studied, two distinct and successive phases of sleep, slow wave (SW), and rapid eye movement (REM), can be recognized on the basis of their EEG profiles and associated behaviors. Both phases have been implicated in the offline sensorimotor processing of daytime events, but the molecular mechanisms remain elusive. We studied brain expression of the plasticity-associated immediate-early gene (IEG) zif-268 during SW and REM sleep in rats exposed to rich sensorimotor experience in the preceding waking period. Whereas nonexposed controls show generalized zif-268 down-regulation during SW and REM sleep, zif-268 is upregulated during REM sleep in the cerebral cortex and the hippocampus of exposed animals. We suggest that this phenomenon represents a window of increased neuronal plasticity during REM sleep that follows enriched waking experience.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Aston-Jones, G., & Bloom, F. (1981) · The Journal of Neuroscience · doi:10.1523/jneurosci.01-08-00876.1981 · Cited by 1,960
Pattern and time course of immediate early gene expression in rat brain following acute stress
Cullinan, W. E., Herman, J. P., Battaglia, D. F., Akil, H., & Watson, S. J. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00355-9 · Cited by 1,056
Dependence on REM Sleep of Overnight Improvement of a Perceptual Skill
Karni, A., Tanne, D., Rubenstein, B. S., Askenasy, J. J. M., & Sagi, D. (1994) · Science · doi:10.1126/science.8036518 · Cited by 1,002
The sequential hypothesis of the function of sleep
Giuditta, A., Ambrosini, M. V., Montagnese, P., Mandile, P., Cotugno, M., Zucconi, G. G., & Vescia, S. (1995) · Behavioural Brain Research · doi:10.1016/0166-4328(95)00012-i · Cited by 382
Lengthening of REM sleep duration consecutive to learning in the rat
Lucero, M. A. (1970) · Brain Research · doi:10.1016/0006-8993(70)90299-4 · Cited by 143
Cited by
Diekelmann, S., & Born, J. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2762 · Cited by 3,760
Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783
The organization of recent and remote memories
Frankland, P. W., & Bontempi, B. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1607 · Cited by 2,138
Sleep-dependent memory consolidation
Stickgold, R. (2005) · Nature · doi:10.1038/nature04286 · Cited by 1,857
The role of sleep in learning and memory
Maquet, P. (2001) · Science · doi:10.1126/science.1062856 · Cited by 1,177
Sleep-Dependent Learning and Memory Consolidation
Walker, M. P., & Stickgold, R. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.031 · Cited by 1,113
The Neurobiology of Sleep: Genetics, cellular physiology and subcortical networks
Pace-Schott, E. F., & Hobson, J. A. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn895 · Cited by 937
Mammalian Play: Training for the Unexpected
Spinka, M., Newberry, R. C., & Bekoff, M. (2001) · The Quarterly Review of Biology · doi:10.1086/393866 · Cited by 817
Sleep, learning, and dreams: off-line memory reprocessing
Stickgold, R., Hobson, J. A., Fosse, R., & Fosse, M. (2001) · Science · doi:10.1126/science.1063530 · Cited by 762
Experience-dependent changes in cerebral activation during human REM sleep
Maquet, P., Laureys, S., Peigneux, P., Fuchs, S., Petiau, C., Phillips, C., Aerts, J., Del Fiore, G., Degueldre, C., Meulemans, T., et al. (2000) · Nature Neuroscience · doi:10.1038/77744 · Cited by 747
Locus coeruleus: a new look at the blue spot
Poe, G. R., Foote, S., Eschenko, O., Johansen, J. P., Bouret, S., Aston-Jones, G., Harley, C. W., Manahan-Vaughan, D., Weinshenker, D., Valentino, R., et al. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-0360-9 · Cited by 720
Fast-Forward Playback of Recent Memory Sequences in Prefrontal Cortex During Sleep
Euston, D. R., Tatsuno, M., & McNaughton, B. L. (2007) · Science · doi:10.1126/science.1148979 · Cited by 586
REM sleep selectively prunes and maintains new synapses in development and learning
Li, W., Ma, L., Yang, G., & Gan, W.-B. (2017) · Nature Neuroscience · doi:10.1038/nn.4479 · Cited by 543
Sleep Enhances Plasticity in the Developing Visual Cortex
Frank, M. G., Issa, N. P., & Stryker, M. P. (2001) · Neuron · doi:10.1016/s0896-6273(01)00279-3 · Cited by 523
Theta and gamma coordination of hippocampal networks during waking and rapid eye movement sleep.
Montgomery, S. M., Sirota, A., & Buzsaki, G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1227-08.2008 · Cited by 371
Memory trace reactivation in hippocampal and neocortical neuronal ensembles
Sutherland, G. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00079-9 · Cited by 384
Sleeping brain, learning brain. The role of sleep for memory systems
Peigneux, P., Laureys, S., Delbeuck, X., & Maquet, P. (2001) · Neuroreport · doi:10.1097/00001756-200112210-00001 · Cited by 347
Clayton, D. F. (2000) · Neurobiology of Learning and Memory · doi:10.1006/nlme.2000.3967 · Cited by 322
Ribeiro, S., Gervasoni, D., Soares, E. S., Zhou, Y., Lin, S.-C., Pantoja, J., Lavine, M., & Nicolelis, M. A. L. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020024 · Cited by 272
Self-citationThe role of REM sleep theta activity in emotional memory
Hutchison, I. C., & Rathore, S. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01439 · Cited by 245
Mechanisms of sleep-dependent consolidation of cortical plasticity
Aton, S. J., Seibt, J., Dumoulin, M., Jha, S. K., Steinmetz, N., Coleman, T., Naidoo, N., & Frank, M. G. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.007 · Cited by 244
Suppression of hippocampal plasticity‐related gene expression by sleep deprivation in rats
Guzman‐Marin, R., Ying, Z., Suntsova, N., Methippara, M., Bashir, T., Szymusiak, R., Gomez‐Pinilla, F., & McGinty, D. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.115287 · Cited by 206
The role of rapid eye movement sleep for amygdala-related memory processing
Genzel, L., Spoormaker, V. I., Konrad, B. N., & Dresler, M. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.01.008 · Cited by 161
The supramammillary nucleus and the claustrum activate the cortex during REM sleep
Renouard, L., Billwiller, F., Ogawa, K., Clément, O., Camargo, N., Abdelkarim, M., Gay, N., Scoté-Blachon, C., Touré, R., Libourel, P.-A., et al. (2015) · Science Advances · doi:10.1126/sciadv.1400177 · Cited by 152
Effects of Skilled Training on Sleep Slow Wave Activity and Cortical Gene Expression in the Rat
Hanlon, E. C., Faraguna, U., Vyazovskiy, V. V., Tononi, G., & Cirelli, C. (2009) · Sleep · doi:10.1093/sleep/32.6.719 · Cited by 148
The Role of Sleep in Memory Consolidation and Brain Plasticity: Dream or Reality?
Frank, M. G., & Benington, J. H. (2006) · The Neuroscientist · doi:10.1177/1073858406293552 · Cited by 143
Fu, J., Li, P., Ouyang, X., Gu, C., Song, Z., Gao, J., Han, L., Feng, S., Tian, S., & Hu, B. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.10.050 · Cited by 129
Learning and sleep: the sequential hypothesis
Ambrosini, M. V., & Giuditta, A. (2001) · Sleep Medicine Reviews · doi:10.1053/smrv.2001.0180 · Cited by 108
Hagewoud, R., Whitcomb, S. N., Heeringa, A. N., Havekes, R., Koolhaas, J. M., & Meerlo, P. (2010) · Sleep · doi:10.1093/sleep/33.10.1315 · Cited by 99
Romcy‐Pereira, R., & Pavlides, C. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03808.x · Cited by 95
Ulloor, J., & Datta, S. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03378.x · Cited by 89
Roth, D. A.-E., Kishon-Rabin, L., Hildesheimer, M., & Karni, A. (2005) · Learning & Memory · doi:10.1101/87505 · Cited by 89
Alger, S. E., Lau, H., & Fishbein, W. (2012) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2012.06.003 · Cited by 86
Schema-conformant memories are preferentially consolidated during REM sleep
Durrant, S. J., Cairney, S. A., McDermott, C., & Lewis, P. A. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.02.011 · Cited by 75
Relational Memory: A Daytime Nap Facilitates the Abstraction of General Concepts
Lau, H., Alger, S. E., & Fishbein, W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027139 · Cited by 75
Fear conditioning increases NREM sleep.
Hellman, K., & Abel, T. (2007) · Behavioral Neuroscience · doi:10.1037/0735-7044.121.2.310 · Cited by 62
Rasch, B., Gais, S., & Born, J. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.6 · Cited by 57
Memory corticalization triggered by REM sleep: mechanisms of cellular and systems consolidation
Almeida-Filho, D. G., Queiroz, C. M., & Ribeiro, S. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2886-9 · Cited by 38
Self-citationRibeiro, S., & Stickgold, R. (2014) · Trends in Neuroscience and Education · doi:10.1016/j.tine.2014.02.004 · Cited by 37
Self-citationKarashima, A., Katayama, N., & Nakao, M. (2007) · Brain Research · doi:10.1016/j.brainres.2007.08.060 · Cited by 20
Metadata
- Authors
- Ribeiro, S., Goyal, V., Mello, C. V., & Pavlides, C.
- Venue
- Learning & Memory
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1999-09-01
- Volume
- 6
- Issue
- 5
- Pages
- 500-508
- ISSN
- 1072-0502 (ISSN-L)
- 1549-5485
- OpenAlex
- W1997369378
- Cited by
- 259
- References
- 6
- Type
- posted content
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
