Cited by 56Smoking Behavior and CessationSuicide and Self-Harm StudiesSubstance Abuse Treatment and Outcomes

Depressive mood, suicide ideation and anxiety in smokers who do and smokers who do not manage to stop smoking after a target quit day

Berlin, Ivan, Chen, Henian, Covey, Lirio S.·2010·Addiction

Abstract

Aims The effect of successful and unsuccessful smoking cessation on depressive mood, anxiety‐ and suicide‐related outcomes is unclear. The aim of this secondary analysis was to explore the relationship between abstinence status and these outcomes. Design Cohort of adult smokers attempting to stop smoking. Smoking status was assessed by a daily diary; depressed mood, anxiety and suicidal tendencies by the Hamilton Depression Rating Scale (HDRS). The association of complete and point‐prevalence abstinence with the HDRS variables was assessed using multi‐level linear regression models. Setting Randomized trial of sertraline versus placebo for smoking cessation with weekly behavioural support provided in a clinic. Participants A total of 133 adult smokers with past major depression. Findings Pre‐quit mood scores did not predict smoking status post‐quit day. Both continuous and point‐prevalence abstainers had significantly lower total HDRS, suicide and anxiety scores, adjusted for all potential confounders, during the period following quit day than did non‐abstainers who experienced a significant mood deterioration. There was a significant effect of sertraline on post‐quit HDRS scores but not on abstinence. Conclusions Contrary to expectation, smoking abstinence among smokers with a history of major depression did not lead to increase in depression, anxiety or suicide ideation; however, failed quit attempts did. Persisting with a quit attempt while unable to achieve abstinence may be associated with mood deterioration.

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Crossref · 10.1111/j.1360-0443.2010.03109.x

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  • Previous data from small cessation trials and recent data from population surveys suggested that relapse in a quit attempt may predict an increase in depressive symptoms.

    “Previous data from small cessation trials [34, 35] and recent data from population surveys suggested that relapse in a quit attempt may predict an increase in depressive symptoms [36].”

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Authors
Berlin, I., Chen, H., & Covey, L. S.
Affiliations
  • Inserm (FR)
  • Winthrop-University Hospital (US)
  • Columbia University Irving Medical Center (US)
Corresponding author
Berlin, Ivan
Venue
Addiction
Publisher
Wiley
Published
2010-09-15
Volume
105
Issue
12
Pages
2209-2216
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
OpenAlex
W1585571950
Cited by
56
References
43
Citations by year
2025: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 4 · 2015: 6 · 2014: 8 · 2013: 8 · 2012: 7
FWCI
4.98
Type
journal article
Language
en
Open access
closed
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
Funders
Pfizer
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
smoking cessation, smoking abstinence, depressive mood, suicidal ideation, anxiety, major depressive disorder, sertraline, behavioral support
MeSH terms
Adolescent, Adult, Aged, Anxiety, Depression, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Male, Medical Records, Middle Aged, Patient Acceptance of Health Care, Placebos, Psychiatric Status Rating Scales, Recurrence, Smoking, Linear Models, Smoking Cessation, Selective Serotonin Reuptake Inhibitors, Sertraline, Young Adult, Suicidal Ideation

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