Changes in gut hormones after bariatric surgery
Abstract
Summary: Bariatric surgery is one of the most effective treatments for achieving long‐term weight loss in morbidly obese patients. Bariatric surgery causes weight loss through substantial decline of hunger and increased satiety. Recently our understanding of neuroendocrine regulation of food intake and weight gain, especially regarding the role of gut hormones, has significantly increased. The changes in these hormones following bariatric surgery can partly explain the mechanism behind weight loss achieved through these procedures. In this paper, we review the effect bariatric procedures have on different gut hormone levels and how they in turn can alter the complex neuroendocrine regulation of energy homeostasis.
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Prospective side-by-side comparisons of fasting and postprandial hormonal changes after LAGB and RYGB are lacking.
“A number of other studies have characterized changes in gut hormones after bariatric surgery but prospective studies of a side-by-side comparison of fasting and postprandial hormonal changes after LAGB and RYGB are lacking (12).”
From Prospective study of gut hormone and metabolic changes after adjustable gastric banding and Roux-en-Y gastric bypass (2009) · cites this paper as [12]
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- Authors
- Vincent, R. P., & Le Roux, C. W.
- Affiliations
- King's College Hospital (GB)
- ORCID
- Vincent, R. P.
- Venue
- Clinical Endocrinology
- Publisher
- Wiley
- Published
- 2008-07-15
- Volume
- 69
- Issue
- 2
- Pages
- 173-179
- ISSN
- 0300-0664 (ISSN-L)
- 1365-2265
- OpenAlex
- W1982931011
- Cited by
- 100
- References
- 71
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 5 · 2022: 5 · 2021: 4 · 2020: 8 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 2 · 2014: 7 · 2013: 4 · 2012: 13
- FWCI
- 1.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute for Health and Care Research (DHCS/05/05)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Pharmacology › Pharmacology and Obesity Treatment
- Keywords
- bariatric surgery, gastrointestinal hormones, morbid obesity, weight loss, satiety, hunger, neuroendocrine regulation, energy homeostasis, food intake regulation
- MeSH terms
- Energy Metabolism, Gastrointestinal Hormones, Homeostasis, Humans, Obesity, Morbid, Bariatric Surgery, Ghrelin
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