Cited by 205Regulation of Appetite and ObesityObesity, Physical Activity, DietPhysical Activity and Health

Nonexercise activity thermogenesis – liberating the life‐force

Levine, J. A.·2007·Journal of Internal Medicine

Abstract

Obesity occurs when energy intake exceeds energy expenditure over a protracted period of time. The energy expenditure associated with everyday activity is called NEAT (Nonexercise activity thermogenesis). NEAT varies between two people of similar size by 2000 kcal day −1 because of people’s different occupations and leisure‐time activities. Data support the central hypothesis that NEAT is pivotal in the regulation of human energy expenditure and body weight regulation and that NEAT is important for understanding the cause and effective treatment for obesity.

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Crossref · 10.1111/j.1365-2796.2007.01842.x

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95 of 95 references verified0 citation errors · 0 not checkable

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  • Differences in energy balance as little as 71 kJ/day (17 kcal) could theoretically lead to a weight gain or loss of 1 kg/year.

    “For example, differences in energy balance as little as in 71 kJ/day (17 kcal), which is approximately the energy utilized in standing for one hour, and only about 0.6% of daily total energy expenditure, could theoretically lead to a weight gain or loss of 1 kg/year 23,41–43.”

    From Cellular bioenergetics as a target for obesity therapy (2010) · cites this paper as [43]

  • NEAT plays an important role in dissipating excess energy to preserve leanness in adult humans.

    “NEAT is energy burned by movement other than exercise, such as fidgeting, maintenance of posture, and other activities of daily life, and has been found to play an important role in dissipating excess energy to preserve leanness in adult humans 43.”

    From Cellular bioenergetics as a target for obesity therapy (2010) · cites this paper as [43]

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Authors
Levine, J. A.
Affiliations
Mayo Clinic (US)
Corresponding author
Levine, J. A.
Venue
Journal of Internal Medicine
Publisher
Wiley
Published
2007-08-09
Volume
262
Issue
3
Pages
273-287
ISSN
  • 0954-6820 (ISSN-L)
  • 1365-2796
OpenAlex
W2113493782
Cited by
205
References
96
Citations by year
2026: 4 · 2025: 7 · 2024: 4 · 2023: 6 · 2022: 3 · 2021: 10 · 2020: 14 · 2019: 9 · 2018: 10 · 2017: 11 · 2016: 5 · 2015: 14 · 2014: 8 · 2013: 20 · 2012: 21
FWCI
1.56
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institute of Diabetes and Digestive and Kidney Diseases (P30DK050456, R01DK063226, DK50456, R01DK066270, DK 63226, DK 66270, DK-56650, R01DK056650)
  • National Center for Research Resources (RR 0585, M01RR000585)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
Keywords
energy expenditure, obesity, body weight regulation, daily physical activity, occupational activity, leisure-time activities, energy balance
MeSH terms
Activities of Daily Living, Body Composition, Energy Intake, Energy Metabolism, Environment Design, Humans, Life Style, Models, Biological, Obesity, Exercise, Thermogenesis

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