Cited by 277Skin Protection and AgingPhytochemicals and Antioxidant Activitiesmelanin and skin pigmentation

Botanical antioxidants in the prevention of photocarcinogenesis and photoaging

Afaq, Farrukh, Mukhtar, Hasan·2006·Experimental Dermatology

Abstract

Exposure of the skin to ultraviolet (UV) radiation, particularly its UV-B component (280-320 nm), from the sun results in erythema, edema, hyperplasia, hyperpigmentation, sunburn cells, immunosuppression, photoaging, and skin cancer. Amongst these various adverse effects of UV-B radiation, skin cancer and photoaging are of great concern. More recent changes in lifestyle have led to a significant increase in the amount of UV-B radiation people receive leading to a surge in the incidence of skin cancer and photoaging. As these trends are likely to continue in the foreseeable future, the adverse effect of UV-B has become a major human health concern. Therefore, development of novel strategies to reduce the occurrence of skin cancer and delay the process of photoaging are highly desirable goals. One approach to reduce their occurrence is through photochemoprevention, which we define as the use of agents capable of ameliorating the adverse effects of UV-B on the skin. Photochemoprevention via use of botanical antioxidants, present in the common diet of human have gained considerable attention as photochemopreventive agents for human use. Many such agents have also found a place in skin care products. This review will focus on the effects of selected botanical antioxidants in the prevention of photocarcinogenesis and photoaging.

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Crossref · 10.1111/j.1600-0625.2006.00466.x

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  • The presence of antioxidants has been shown to be linked to a lower frequency of ROS-induced photoaging.

    “The presence of antioxidants has been shown to be linked to a lower frequency of ROS-induced photoaging [201].”

    From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [201]

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Authors
Afaq, F., & Mukhtar, H.
Affiliations
University of Wisconsin–Madison (US)
Corresponding author
Mukhtar, Hasan
Venue
Experimental Dermatology
Publisher
Wiley
Published
2006-07-31
Volume
15
Issue
9
Pages
678-684
ISSN
  • 0906-6705 (ISSN-L)
  • 1600-0625
OpenAlex
W2078682475
Cited by
277
References
57
Citations by year
2026: 4 · 2025: 3 · 2024: 8 · 2023: 12 · 2022: 7 · 2021: 10 · 2020: 16 · 2019: 10 · 2018: 14 · 2017: 16 · 2016: 22 · 2015: 17 · 2014: 20 · 2013: 19 · 2012: 17
FWCI
2.50
Type
journal article
Language
en
Open access
closed
Locations
  • Experimental Dermatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
Keywords
photocarcinogenesis, photoaging, UV-B radiation, skin cancer, skin care products, dietary antioxidants
MeSH terms
Resveratrol, Antioxidants, Humans, Plant Extracts, Skin, Skin Neoplasms, Stilbenes, Tea, Skin Aging, Genistein, Lythraceae

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