The prevention of osteoporosis and sarcopenia in older adults
Abstract
Osteoporosis and sarcopenia are common in older adults. Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Bone fractures can result in changes in posture, pain, the need for surgical repair and functional impairment. Sarcopenia is the progressive and generalized loss of skeletal muscle mass, strength and/or physical performance. Older adults with sarcopenia experience increased risk of frailty, disability, hospitalizations, mortality, and a reduced quality of life. In this narrative review we provide guidance regarding the prevention of both osteoporosis and sarcopenia, including interventions that prevent both conditions from occurring, recommended screening and treatment to prevent progression.
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Evidence suggests that sarcopenia can be prevented and possibly reversed through lifestyle interventions such as resistance exercise and proper nutritional support.
“Evidence suggests that sarcopenia can be prevented and possibly reversed through lifestyle interventions such as resistance exercise and proper nutritional support (157, 158).”
From From mitochondria to sarcopenia: role of 17β-estradiol and testosterone (2023) · cites this paper as [157]
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- Authors
- Coll, P. P., Phu, S., Hajjar, S. H., Kirk, B., Duque, G., & Taxel, P.
- Affiliations
- UConn Health (US)
- The University of Melbourne (AU)
- Taibah University (SA)
- Corresponding author
- Coll, Patrick P.
- Venue
- Journal of the American Geriatrics Society
- Publisher
- Wiley
- Published
- 2021-02-23
- Volume
- 69
- Issue
- 5
- Pages
- 1388-1398
- ISSN
- 0002-8614 (ISSN-L)
- 1532-5415
- OpenAlex
- W3129939391
- Cited by
- 101
- References
- 71
- Citations by year
- 2026: 8 · 2025: 23 · 2024: 28 · 2023: 21 · 2022: 15 · 2021: 6
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Geriatrics Society (publishedVersion)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- osteoporosis prevention, sarcopenia prevention, older adults, bone fragility, fracture risk, frailty, muscle mass and strength, physical performance, screening, treatment
- MeSH terms
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Osteoporosis, Sarcopenia
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