A Transcriptively Active Complex of APP with Fe65 and Histone Acetyltransferase Tip60

Cao, Xinwei, Südhof, Thomas C.·2001·Science

Cited by (133)

Items 101–133 of 133

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  3. The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing
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  4. DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing
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  7. BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease
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  8. More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration
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  9. Modulation of Statin-Activated Shedding of Alzheimer APP Ectodomain by ROCK
    Pedrini, Steve, Carter, Troy L, Prendergast, George, Petanceska, Suzana, Ehrlich, Michelle E, Gandy, Sam · 2005 · PLoS Medicine
  10. Treatment with an Amyloid-β Antibody Ameliorates Plaque Load, Learning Deficits, and Hippocampal Long-Term Potentiation in a Mouse Model of Alzheimer's Disease
    Hartman, Richard E., Izumi, Yukitoshi, Bales, Kelly R., Paul, Steven M., Wozniak, David F., Holtzman, David M. · 2005 · The Journal of Neuroscience
  11. Making the final cut: Pathogenic amyloid-β peptide generation by γ-secretase
    Steiner, Harald, Fukumori, Akio, Tagami, Shinji, Okochi, Masayasu · 2018 · Cell Stress
  12. Biochemistry and Molecular Biology of Amyloid β‐Protein and the Mechanism of Alzheimer's Disease
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  13. A Mitocentric View of Alzheimer's Disease Suggests Multi-Faceted Treatments
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  14. F-spondin interaction with the apolipoprotein E receptor ApoEr2 affects processing of amyloid precursor protein
    Hoe, Hyang-Sook, Wessner, David, Beffert, Uwe, Becker, Amanda G., Matsuoka, Yasuji, Rebeck, G. William · 2005 · Molecular and Cellular Biology
  15. Functional coordination of alternative splicing in the mammalian central nervous system
    Fagnani, Matthew, Barash, Yoseph, Ip, Joanna Y, Misquitta, Christine, Pan, Qun, Saltzman, Arneet L, Shai, Ofer, Lee, Leo, Rozenhek, Aviad, Mohammad, Naveed et al. · 2007 · Genome Biology
  16. The keystone of Alzheimer pathogenesis might be sought in Aβ physiology
    Puzzo, D., Gulisano, W., Arancio, O., Palmeri, A. · 2015 · Neuroscience
  17. APP Function and Lipids: A Bidirectional Link
    Grimm, Marcus O. W., Mett, Janine, Grimm, Heike S., Hartmann, Tobias · 2017 · Frontiers in Molecular Neuroscience
  18. Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing
    Eckert, Gunter P., Chang, Steffi, Eckmann, Janett, Copanaki, Ekaterini, Hagl, Stephanie, Hener, Uwe, Müller, Walter E., Kögel, Donat · 2011 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  19. Amyloid precursor protein (APP) May act as a substrate and a recognition unit for CRL4CRBN and Stub1 E3 ligases facilitating ubiquitination of proteins involved in presynaptic functions and neurodegeneration
    Del Prete, Dolores, Rice, Richard C., Rajadhyaksha, Anjali M., D'Adamio, Luciano · 2016 · Journal of Biological Chemistry
  20. Drugs targeting alzheimer’s disease: Some things old and some things new
    Michaelis, Mary L. · 2003 · The Journal of Pharmacology and Experimental Therapeutics
  21. Molecular and cellular aspects of age-related cognitive decline and Alzheimer’s disease
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  22. Mutations in APP have independent effects on Aβ and CTFγ generation
    Hecimovic, Silva, Wang, Jun, Dolios, Georgia, Martinez, Maribel, Wang, Rong, Goate, Alison M. · 2004 · Neurobiology of Disease
  23. Modeling the complex pathology of Alzheimer's disease in Drosophila
    Fernandez-Funez, Pedro, de Mena, Lorena, Rincon-Limas, Diego E. · 2015 · Experimental Neurology
  24. APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells
    Zhou, Fangfang, van Laar, Theo, Huang, Huizhe, Zhang, Long · 2011 · Protein & Cell
  25. LRAD3, A Novel Low-Density Lipoprotein Receptor Family Member That Modulates Amyloid Precursor Protein Trafficking
    Ranganathan, S., Noyes, N. C., Migliorini, M., Winkles, J. A., Battey, F. D., Hyman, B. T., Smith, E., Yepes, M., Mikhailenko, I., Strickland, D. K. · 2011 · Journal of Neuroscience
  26. Presenilins in synaptic function and disease.
    Ho, Angela, Shen, Jie · 2011 · Trends in Molecular Medicine
  27. Clinical, biological, and imaging features of monogenic Alzheimer’s disease
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  28. FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth
    Cheung, Hei Nga Maggie, Dunbar, Charlotte, Mórotz, Gábor M., Cheng, Wai Hang, Chan, Ho Yin Edwin, Miller, Christopher C. J., Lau, Kwok‐Fai · 2014 · The FASEB Journal
  29. The cytoplasmic adaptor protein X11α and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement
    Minami, S. Sakura, Sung, You Me, Dumanis, Sonya B., Chi, Seong Hwan, Burns, Mark P., Ann, Eun-Jung, Suzuki, Toshiharu, Turner, R. Scott, Park, Hee-Sae, Pak, Daniel T. S. et al. · 2010 · The FASEB Journal
  30. Differential processing of amyloid precursor protein in brain and in peripheral blood leukocytes
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  31. Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease—From Brain Starch to Bench and Bedside
    Pawlowski, Matthias, Meuth, Sven, Duning, Thomas · 2017 · Diagnostics
  32. A Flanking Gene Problem Leads to the Discovery of a Gprc5b Splice Variant Predominantly Expressed in C57Bl/6J Mouse Brain and in Maturing Neurons
    Cool, Bethany H., Chan, Guy C-K., Lee, Lin, Oshima, Junko, Martin, George M., Hu, Qubai · 2010 · PLoS ONE
  33. Cyclopamine Modulates γ-Secretase-mediated Cleavage of Amyloid Precursor Protein by Altering Its Subcellular Trafficking and Lysosomal Degradation
    Vorobyeva, Anna G., Lee, Randall, Miller, Sean, Longen, Charles, Sharoni, Michal, Kandelwal, Preeti J., Kim, Felix J., Marenda, Daniel R., Saunders, Aleister J. · 2014 · Journal of Biological Chemistry