Cited by 272Memory and Neural MechanismsMemory Processes and InfluencesNeuroscience and Neuropharmacology Research

Role of Secondary Sensory Cortices in Emotional Memory Storage and Retrieval in Rats

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Sacco, Tiziana, Sacchetti, Benedetto·2010·Science

Abstract

The Storage of Emotions: The neural mechanisms involved in emotional learning are well understood. However, how and where emotional memories are stored is still largely unclear. Sacco and Sacchetti (p. 649 ) now show that Pavlovian fear memories are stored in a modality-specific way in the secondary, but not primary, sensory cortices. The site of storage depended on whether the conditioned stimulus was visual, auditory, or olfactory. Only “old,” not new, memories were stored in this way, and lesions of secondary cortices, while disrupting the old memories, did not prevent the acquisition of new memories.

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Crossref · 10.1126/science.1183165

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  • Coherence (phase alignment) between theta oscillations in the secondary visual cortex (V2) and the BLA is necessary for successful recall of remote fear memories.

    “For instance, coherence (phase alignment) between theta oscillations in the secondary visual cortex (V2) and the BLA is necessary for successful recall of remote fear memories [93, 94].”

    From The extracellular matrix and perineuronal nets in memory (2022) · cites this paper as [93]

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Authors
Sacco, T., & Sacchetti, B.
Affiliations
University of Turin (IT)
Corresponding author
Sacchetti, Benedetto
Venue
Science
Published
2010-08-06
Volume
329
Issue
5992
Pages
649-656
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2075293125
Cited by
272
References
39
Citations by year
2026: 3 · 2025: 15 · 2024: 13 · 2023: 14 · 2022: 15 · 2021: 14 · 2020: 18 · 2019: 24 · 2018: 16 · 2017: 19 · 2016: 23 · 2015: 18 · 2014: 13 · 2013: 26 · 2012: 14
FWCI
12.96
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • Institutional Research Information System University of Turin (University of Turin) (submittedVersion, other-oa)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
emotional memory, fear memory, memory storage, memory retrieval, excitotoxic lesions, memory persistence, sensory modality specificity, corticocortical connections, synaptic strengthening
MeSH terms
Protein Kinase C zeta, Acoustic Stimulation, Amnesia, Amygdala, Animals, Auditory Cortex, Conditioning, Psychological, Emotions, Fear, Habituation, Psychophysiologic, Male, Memory, Odorants, Olfactory Pathways, Photic Stimulation, Protein Kinase C, Synapses, Visual Cortex, Rats, Wistar, Rats, Early Growth Response Protein 1

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