Midbrain fMRI: Applications, Limitations and Challenges

Düzel, Emrah; Guitart-Masip, Marc; Maass, Anne; Hämmerer, Dorothea; Betts, Matthew J.; Speck, Oliver; Weiskopf, Nikolaus; Kanowski, Martin

doi:10.1007/978-1-4899-7591-1_20

Cited by 16Advanced MRI Techniques and ApplicationsAdvanced Neuroimaging Techniques and ApplicationsFunctional Brain Connectivity Studies

Midbrain fMRI: Applications, Limitations and Challenges

Düzel, Emrah, Guitart-Masip, Marc, Maass, Anne, Hämmerer, Dorothea, Betts, Matthew J., Speck, Oliver, Weiskopf, Nikolaus, Kanowski, Martin·2015·Biological Magnetic Resonance

DOI 10.1007/978-1-4899-7591-1_20

Open this paper in CoChat — free account

Integrity signals

Registry

Crossref · 10.1007/978-1-4899-7591-1_20

Cites

128 of 128 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The slice angle was approximately 20° away from the plane of the standard anterior commissure-posterior commissure to avoid placing the SN/VTA and the sphenoid sinus in the same slice plane, reducing geometric distortion to the point that standard distortion correction methods could be applied.
“The angle of the slices was approximately 20° away from the plane of the standard anterior commissure–posterior commissure to avoid placing the SN/VTA and the sphenoid sinus in the same slice plane. This reduced geometric distortion to the point that standard distortion correction methods could be applied28.”
From Acute social isolation evokes midbrain craving responses similar to hunger (2020) · cites this paper as [28]

Unified segmentation
Ashburner, J., & Friston, K. J. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.02.018 · Cited by 7,507 · see citing works
A reproducible evaluation of ANTs similarity metric performance in brain image registration
Avants, B. B., Tustison, N. J., Song, G., Cook, P. A., Klein, A., & Gee, J. C. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2010.09.025 · Cited by 4,796 · see citing works
An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance
Aston-Jones, G., & Cohen, J. D. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135709 · Cited by 4,472 · see citing works
The reward circuit: linking primate anatomy and human imaging
Haber, S. N., & Knutson, B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.129 · Cited by 3,718 · see citing works
Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging.
Ogawa, S., Tank, D. W., Menon, R., Ellermann, J. M., Kim, S. G., Merkle, H., & Ugurbil, K. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.13.5951 · Cited by 3,681 · see citing works
The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes
Berridge, C. W., & Waterhouse, B. D. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00143-7 · Cited by 2,529 · see citing works
Beyond mind-reading: multi-voxel pattern analysis of fMRI data
Norman, K. A., Polyn, S. M., Detre, G. J., & Haxby, J. V. (2006) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.07.005 · Cited by 2,271 · see citing works
Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration
Klein, A., Andersson, J., Ardekani, B. A., Ashburner, J., Avants, B., Chiang, M.-C., Christensen, G. E., Collins, D. L., Gee, J., Hellier, P., et al. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.12.037 · Cited by 2,227 · see citing works
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
O'Doherty, J., Dayan, P., Schultz, J., Deichmann, R., Friston, K., & Dolan, R. J. (2004) · Science · doi:10.1126/science.1094285 · Cited by 2,088 · see citing works
Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle
Aston-Jones, G., & Bloom, F. (1981) · The Journal of Neuroscience · doi:10.1523/jneurosci.01-08-00876.1981 · Cited by 1,960 · see citing works
The locus coeruleus and noradrenergic modulation of cognition
Sara, S. J. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2573 · Cited by 1,848 · see citing works
Iron, brain ageing and neurodegenerative disorders
Zecca, L., Youdim, M. B. H., Riederer, P., Connor, J. R., & Crichton, R. R. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1537 · Cited by 1,801 · see citing works
Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum
Haber, S. N., Fudge, J. L., & McFarland, N. R. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-06-02369.2000 · Cited by 1,610 · see citing works
Multiband multislice GE‐EPI at 7 tesla, with 16‐fold acceleration using partial parallel imaging with application to high spatial and temporal whole‐brain fMRI
Moeller, S., Yacoub, E., Olman, C. A., Auerbach, E., Strupp, J., Harel, N., & Uğurbil, K. (2010) · Magnetic Resonance in Medicine · doi:10.1002/mrm.22361 · Cited by 1,586 · see citing works
Interpreting the BOLD Signal
Logothetis, N. K., & Wandell, B. A. (2004) · Annual Review of Physiology · doi:10.1146/annurev.physiol.66.082602.092845 · Cited by 1,568 · see citing works
Two types of dopamine neuron distinctly convey positive and negative motivational signals
Matsumoto, M., & Hikosaka, O. (2009) · Nature · doi:10.1038/nature08028 · Cited by 1,378 · see citing works
Multiplexed echo planar imaging for sub-second whole brain FMRI and fast diffusion imaging
Feinberg, D. A., Moeller, S., Smith, S. M., Auerbach, E., Ramanna, S., Glasser, M. F., Miller, K. L., Ugurbil, K., & Yacoub, E. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015710 · Cited by 1,296 · see citing works
Efferent connections of the substantia nigra and ventral tegmental area in the rat
Beckstead, R. M., Domesick, V. B., & Nauta, W. J. H. (1979) · Brain Research · doi:10.1016/0006-8993(79)91001-1 · Cited by 1,293 · see citing works
Lateral habenula as a source of negative reward signals in dopamine neurons
Matsumoto, M., & Hikosaka, O. (2007) · Nature · doi:10.1038/nature05860 · Cited by 1,292 · see citing works
Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission
Floresco, S. B., West, A. R., Ash, B., Moore, H., & Grace, A. A. (2003) · Nature Neuroscience · doi:10.1038/nn1103 · Cited by 1,106 · see citing works
Orienting and reorienting: the locus coeruleus mediates cognition through arousal
Sara, S. J., & Bouret, S. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.011 · Cited by 1,056 · see citing works
Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
Grace, A. A., Floresco, S. B., Goto, Y., & Lodge, D. J. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.03.003 · Cited by 1,034 · see citing works
Neuronal Loss Is Greater in the Locus Coeruleus Than Nucleus Basalis and Substantia Nigra in Alzheimer and Parkinson Diseases
Zarow, C., Lyness, S. A., Mortimer, J. A., & Chui, H. C. (2003) · Archives of Neurology · doi:10.1001/archneur.60.3.337 · Cited by 1,003 · see citing works
Computational roles for dopamine in behavioural control
Montague, P. R., Hyman, S. E., & Cohen, J. D. (2004) · Nature · doi:10.1038/nature03015 · Cited by 966 · see citing works
Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli
Mirenowicz, J., & Schultz, W. (1996) · Nature · doi:10.1038/379449a0 · Cited by 829 · see citing works
Optimized EPI for fMRI studies of the orbitofrontal cortex
Deichmann, R., Gottfried, J. A., Hutton, C., & Turner, R. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00073-9 · Cited by 821 · see citing works
Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli
Brischoux, F., Chakraborty, S., Brierley, D. I., & Ungless, M. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811507106 · Cited by 801 · see citing works
Functional Neuroanatomy of the Noradrenergic Locus Coeruleus: Its Roles in the Regulation of Arousal and Autonomic Function Part I: Principles of Functional Organisation
Samuels, E., & Szabadi, E. (2008) · Current Neuropharmacology · doi:10.2174/157015908785777229 · Cited by 766 · see citing works
Reward-related FMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation
Wittmann, B. C., Schott, B. H., Guderian, S., Frey, J. U., Heinze, H.-J., & Düzel, E. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.010 · Cited by 698 · see citing works
Self-citation
The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses.
Jhou, T. C., Fields, H. L., Baxter, M. G., Saper, C. B., & Holland, P. C. (2009) · Neuron · doi:10.1016/j.neuron.2009.02.001 · Cited by 696 · see citing works
Image Distortion Correction in fMRI: A Quantitative Evaluation
Hutton, C., Bork, A., Josephs, O., Deichmann, R., Ashburner, J., & Turner, R. (2002) · NeuroImage · doi:10.1006/nimg.2001.1054 · Cited by 667 · see citing works
BOLD responses reflecting dopaminergic signals in the human ventral tegmental area
D'Ardenne, K., McClure, S. M., Nystrom, L. E., & Cohen, J. D. (2008) · Science · doi:10.1126/science.1150605 · Cited by 661 · see citing works
Comparison of physiological noise at 1.5 T, 3 T and 7 T and optimization of fMRI acquisition parameters
Triantafyllou, C., Hoge, R. D., Krueger, G., Wiggins, C. J., Potthast, A., Wiggins, G. C., & Wald, L. L. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.01.007 · Cited by 648 · see citing works
The optimal template effect in hippocampus studies of diseased populations
Avants, B. B., Yushkevich, P., Pluta, J., Minkoff, D., Korczykowski, M., Detre, J., & Gee, J. C. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.062 · Cited by 640 · see citing works
Locus coeruleus neurons in monkey are selectively activated by attended cues in a vigilance task
Aston-Jones, G., Rajkowski, J., Kubiak, P., & Alexinsky, T. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-07-04467.1994 · Cited by 637 · see citing works
Adaptive gain and the role of the locus coeruleus–norepinephrine system in optimal performance
Aston‐Jones, G., & Cohen, J. D. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20723 · Cited by 630 · see citing works
The connections of the dopaminergic system with the striatum in rats and primates: an analysis with respect to the functional and compartmental organization of the striatum
Joel, D., & Weiner, I. (2000) · Neuroscience · doi:10.1016/s0306-4522(99)00575-8 · Cited by 614 · see citing works
Ventral Tegmental Area Neurons in Learned Appetitive Behavior and Positive Reinforcement
Fields, H. L., Hjelmstad, G. O., Margolis, E. B., & Nicola, S. M. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.30.051606.094341 · Cited by 611 · see citing works
Neurophysiology of the BOLD fMRI Signal in Awake Monkeys
Goense, J. B. M., & Logothetis, N. K. (2008) · Current Biology · doi:10.1016/j.cub.2008.03.054 · Cited by 583 · see citing works
The locus coeruleus: A cytoarchitectonic, golgi and immunohistochemical study in the albino rat
Swanson, L. W. (1976) · Brain Research · doi:10.1016/0006-8993(76)90207-9 · Cited by 518 · see citing works
Absolute Coding of Stimulus Novelty in the Human Substantia Nigra/VTA
Bunzeck, N., & Düzel, E. (2006) · Neuron · doi:10.1016/j.neuron.2006.06.021 · Cited by 503 · see citing works
Self-citation
Mesolimbic Functional Magnetic Resonance Imaging Activations during Reward Anticipation Correlate with Reward-Related Ventral Striatal Dopamine Release
Schott, B. H., Minuzzi, L., Krebs, R. M., Elmenhorst, D., Lang, M., Winz, O. H., Seidenbecher, C. I., Coenen, H. H., Heinze, H.-J., Zilles, K., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2058-08.2008 · Cited by 496 · see citing works
Self-citation
Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease
Sasaki, M., Shibata, E., Tohyama, K., Takahashi, J., Otsuka, K., Tsuchiya, K., Takahashi, S., Ehara, S., Terayama, Y., & Sakai, A. (2006) · Neuroreport · doi:10.1097/01.wnr.0000227984.84927.a7 · Cited by 496 · see citing works
Optimal EPI parameters for reduction of susceptibility-induced BOLD sensitivity losses: A whole-brain analysis at 3 T and 1.5 T
Weiskopf, N., Hutton, C., Josephs, O., & Deichmann, R. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.07.029 · Cited by 488 · see citing works
Self-citation
Extrathalamic Modulation of Cortical Function
Foote, S. L., & Morrison, J. (1987) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.10.030187.000435 · Cited by 480 · see citing works
Retrospective estimation and correction of physiological fluctuation in functional MRI
Hu, X. P., Le, T. H., Parrish, T. B., & Erhard, P. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910340211 · Cited by 474 · see citing works
The anatomical and functional relationship between the P3 and autonomic components of the orienting response
Nieuwenhuis, S., de Geus, E. J. C., & Aston‐Jones, G. (2010) · Psychophysiology · doi:10.1111/j.1469-8986.2010.01057.x · Cited by 451 · see citing works
Ultra-fast MRI of the human brain with simultaneous multi-slice imaging
Feinberg, D. A., & Setsompop, K. (2013) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2013.02.002 · Cited by 434 · see citing works
Nonlinear dynamic causal models for fMRI
Stephan, K. E., Kasper, L., Harrison, L. M., Daunizeau, J., den Ouden, H. E. M., Breakspear, M., & Friston, K. J. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.04.262 · Cited by 416 · see citing works
Magnetic resonance imaging of freely moving objects: prospective real-time motion correction using an external optical motion tracking system
Zaitsev, M., Dold, C., Sakas, G., Hennig, J., & Speck, O. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.01.039 · Cited by 392 · see citing works
Self-citation
Reward expectation, orientation of attention and locus coeruleus‐medial frontal cortex interplay during learning
Bouret, S., & Sara, S. J. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03526.x · Cited by 371 · see citing works
Cortico-striatal connections predict control over speed and accuracy in perceptual decision making
Forstmann, B. U., Anwander, A., Schäfer, A., Neumann, J., Brown, S. D., Wagenmakers, E., Bogacz, R., & Turner, R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004932107 · Cited by 368 · see citing works
Midbrain iron content in early Parkinson disease
Martin, W. R. W., Wieler, M., & Gee, M. (2008) · Neurology · doi:10.1212/01.wnl.0000286384.31050.b5 · Cited by 355 · see citing works
The relevance of iron in the pathogenesis of Parkinson’s disease
Sian‐Hülsmann, J., Mandel, S. A., Youdim, M. B. H., & Riederer, P. F. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07132.x · Cited by 349 · see citing works
The laterodorsal tegmentum is essential for burst firing of ventral tegmental area dopamine neurons
Lodge, D. J., & Grace, A. A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510715103 · Cited by 349 · see citing works
Anatomical Substrates for Glutamate‐Dopamine Interactions
Sesack, S., Carr, D. B., Omelchenko, N., & Pinto, A. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.066 · Cited by 348 · see citing works
κ opioids selectively control dopaminergic neurons projecting to the prefrontal cortex
Margolis, E. B., Lock, H., Chefer, V. I., Shippenberg, T. S., Hjelmstad, G. O., & Fields, H. L. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511159103 · Cited by 326 · see citing works
In vivo mapping of the human locus coeruleus
Keren, N. I., Lozar, C., Harris, K. C., Morgan, P. S., & Eckert, M. A. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.06.012 · Cited by 309 · see citing works
Human reticular formation: Cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons
Mesulam, M. M., Geula, C., Bothwell, M. A., & Hersh, L. B. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902830414 · Cited by 307 · see citing works
Brain motion: measurement with phase-contrast MR imaging.
Enzmann, D. R., & Pelc, N. J. (1992) · Radiology · doi:10.1148/radiology.185.3.1438741 · Cited by 275 · see citing works
Anticipation of novelty recruits reward system and hippocampus while promoting recollection
Wittmann, B. C., Bunzeck, N., Dolan, R. J., & Düzel, E. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.06.038 · Cited by 265 · see citing works
Self-citation
İnsanlarda Yenilik N2 Yanıtı Hedef Uyaranların Zamansal Sınıflamasını Yansıtır
Maraşligil, B., & Ergenoğlu, T. (2011) · Journal of Experimental and Clinical Medicine · doi:10.5835/jecm.omu.28.02.002 · Cited by 255 · see citing works
Compensation of susceptibility-induced bold sensitivity losses in echo-planar fMRI imaging
Deichmann, R., Josephs, O., Hutton, C., Corfield, D. R., & Turner, R. (2002) · NeuroImage · doi:10.1006/nimg.2001.0985 · Cited by 253 · see citing works
Real-time functional magnetic resonance imaging: methods and applications
Weiskopf, N., Sitaram, R., Josephs, O., Veit, R., Scharnowski, F., Goebel, R., Birbaumer, N., Deichmann, R., & Mathiak, K. (2007) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2007.02.007 · Cited by 252 · see citing works
Self-citation
Physiological noise modelling for spinal functional magnetic resonance imaging studies
Brooks, J. C. W., Beckmann, C. F., Miller, K. L., Wise, R. G., Porro, C. A., Tracey, I., & Jenkinson, M. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.09.018 · Cited by 243 · see citing works
Regional and temporal differences in real-time dopamine efflux in the nucleus accumbens during free-choice novelty
Rebec, G. V., Christensen, J. R. C., Guerra, C., & Bardo, M. T. (1997) · Brain Research · doi:10.1016/s0006-8993(97)01004-4 · Cited by 235 · see citing works
Conditioned responses of monkey locus coeruleus neurons anticipate acquisition of discriminative behavior in a vigilance task
Aston‐Jones, G., Rajkowski, J., & Kubiak, P. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00060-2 · Cited by 227 · see citing works
Physiological Noise in Brainstem fMRI
Brooks, J. C. W., Harrison, O. K., Pattinson, K. T. S., & Jenkinson, M. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00623 · Cited by 223 · see citing works
Functional imaging of the human dopaminergic midbrain
Düzel, E., Bunzeck, N., Guitart-Masip, M., Wittmann, B., Schott, B. H., & Tobler, P. N. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.02.005 · Cited by 216 · see citing works
Self-citation
Action dominates valence in anticipatory representations in the human striatum and dopaminergic midbrain
Guitart-Masip, M., Fuentemilla, L., Bach, D. R., Huys, Q. J. M., Dayan, P., Dolan, R. J., & Duzel, E. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.6376-10.2011 · Cited by 216 · see citing works
Self-citation
Locus coeruleus cell loss in the aging human brain: A non‐random process
Manaye, K., McIntire, D., Mann, D. M. A., & German, D. (1995) · The Journal of comparative neurology · doi:10.1002/cne.903580105 · Cited by 212 · see citing works
Pedunculopontine Tegmental Nucleus Controls Conditioned Responses of Midbrain Dopamine Neurons in Behaving Rats
Pan, W. X., & Hyland, B. I. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0277-05.2005 · Cited by 209 · see citing works
The human locus coeruleus: computer reconstruction of cellular distribution
German, D. C., Walker, B., Manaye, K. F., Smith, W. K., Woodward, D., & Aj, N. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-05-01776.1988 · Cited by 208 · see citing works
Two Dimensions of Value: Dopamine Neurons Represent Reward But Not Aversiveness
Fiorillo, C. D. (2013) · Science · doi:10.1126/science.1238699 · Cited by 203 · see citing works
Homeostatic Sleep Pressure and Responses to Sustained Attention in the Suprachiasmatic Area
Schmidt, C., Collette, F., Leclercq, Y., Virginie Sterpenich, A., Vandewalle, G., Berthomier, P., Berthomier, C., Phillips, C. L. M., Tinguely, G., Darsaud, A., et al. (2009) · Science · doi:10.1126/science.1167337 · Cited by 198 · see citing works
Brainstem functional magnetic resonance imaging: Disentangling signal from physiological noise
Harvey, A. K., Pattinson, K. T. S., Brooks, J. C. W., Mayhew, S. D., Jenkinson, M., & Wise, R. G. (2008) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.21623 · Cited by 196 · see citing works
Network interactions in schizophrenia - therapeutic implications.
Carlsson, A., Waters, N., Waters, S., & Carlsson, M. (2000) · Brain research. Brain research reviews · doi:10.1016/s0165-0173(99)00050-8 · Cited by 192 · see citing works
Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI
Minzenberg, M., Watrous, A. J., Yoon, J. H., Ursu, S., & Carter, C. S. (2008) · Science · doi:10.1126/science.1164908 · Cited by 191 · see citing works
Improved segmentation of deep brain grey matter structures using magnetization transfer (MT) parameter maps
Helms, G., Draganski, B., Frackowiak, R. S. J., Ashburner, J., & Weiskopf, N. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.03.053 · Cited by 181 · see citing works
Self-citation
Stereotactic localization of the human pedunculopontine nucleus: atlas-based coordinates and validation of a magnetic resonance imaging protocol for direct localization
Zrinzo, L. U., Zrinzo, L. U., Tisch, S. H., et al. (2008) · Brain · doi:10.1093/brain/awn075 · Cited by 179 · see citing works
Optimized EPI for fMRI studies of the orbitofrontal cortex: compensation of susceptibility-induced gradients in the readout direction
Weiskopf, N., Hutton, C., Josephs, O., Turner, R., & Deichmann, R. (2007) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-006-0067-6 · Cited by 177 · see citing works
Self-citation
Numerous GABAergic Afferents to Locus Ceruleus in the Pericerulear Dendritic Zone: Possible Interneuronal Pool
Aston‐Jones, G., Zhu, Y., & Card, J. P. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5339-03.2004 · Cited by 167 · see citing works
Functional MRI of the Human Amygdala?
Merboldt, K., Fransson, P., Bruhn, H., & Frahm, J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0802 · Cited by 162 · see citing works
Duvernoy's atlas of the human brain stem and cerebellum: high-field MRI, surface anatomy, internal structure, vascularization and 3D sectional anatomy
Naidich, T. P., Duvernoy, H. M., Delman, B. N., et al. (2009) · Zurich Open Repository and Archive (University of Zurich) · Cited by 155 · see citing works
Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease
Gibb, W. R. G. (1992) · Brain Research · doi:10.1016/0006-8993(92)90719-p · Cited by 152 · see citing works
The substantia nigra in Parkinson disease: proton density-weighted spin-echo and fast short inversion time inversion-recovery MR findings.
Oikawa, H., Sasaki, M., Tamakawa, Y., Ehara, S., & Tohyama, K. (2002) · PubMed Central · Cited by 149 · see citing works
Simultaneous imaging of locus coeruleus and substantia nigra with a quantitative neuromelanin MRI approach
Chen, X., Huddleston, D. E., Langley, J. A., Ahn, S., Barnum, C. J., Factor, S. A., Levey, A. I., & Hu, X. P. (2014) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2014.07.003 · Cited by 141 · see citing works
Novelty increases the mesolimbic functional connectivity of the substantia nigra/ventral tegmental area (SN/VTA) during reward anticipation: Evidence from high-resolution fMRI
Krebs, R. M., Heipertz, D., Schuetze, H., & Duzel, E. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.038 · Cited by 135 · see citing works
Optimized 3 T EPI of the amygdalae
Robinson, S., Windischberger, C., Rauscher, A., & Moser, E. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.12.048 · Cited by 133 · see citing works
Activation of Midbrain Structures by Associative Novelty and the Formation of Explicit Memory in HumansPreprint
Schott, B. H., Sellner, D., Lauer, C., Habib, R., Frey, J. U., Guderian, S., Heinze, H., & Düzel, E. (2004) · Learning & Memory · doi:10.1101/lm.75004 · Cited by 130 · see citing works
Self-citation
Age‐related and regional differences in dopamine transporter mRNA expression in human midbrain
Bannon, M. J., & Whitty, C. W. M. (1997) · Neurology · doi:10.1212/wnl.48.4.969 · Cited by 130 · see citing works
Personality traits are differentially associated with patterns of reward and novelty processing in the human substantia nigra/ventral tegmental area
Krebs, R. M., Schott, B. H., & Düzel, E. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.08.019 · Cited by 129 · see citing works
Mesolimbic interaction of emotional valence and reward improves memory formation.
Wittmann, B., Schiltz, K., Boehler, C., & Düzel, E. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2007.11.020 · Cited by 124 · see citing works
Self-citation
Distinct Midbrain and Habenula Pathways Are Involved in Processing Aversive Events in Humans
Hennigan, K., D’Ardenne, K., & McClure, S. M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0927-14.2015 · Cited by 119 · see citing works
Laminar activity in the hippocampus and entorhinal cortex related to novelty and episodic encoding
Maaß, A., Schütze, H., Speck, O., Yonelinas, A. P., Tempelmann, C., Heinze, H., Berron, D., Cárdenas‐Blanco, A., Brodersen, K. H., Stephan, K. E., et al. (2014) · Nature Communications · doi:10.1038/ncomms6547 · Cited by 110 · see citing works
Self-citation
Using High-Resolution MR Imaging at 7T to Evaluate the Anatomy of the Midbrain Dopaminergic System
Eapen, M., Zald, D. H., Gatenby, J. C., Ding, Z., & Gore, J. C. (2010) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2355 · Cited by 109 · see citing works
Activity of Neurochemically Heterogeneous Dopaminergic Neurons in the Substantia Nigra during Spontaneous and Driven Changes in Brain State
Brown, M. T. C., Henny, P., Bolam, J. P., & Magill, P. J. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4423-08.2009 · Cited by 106 · see citing works
The human locus coeruleus 3-D stereotactic anatomy
Fernandes, P. M. P., Regala, J. A. M. D. O. D. B., Correia, F., & Gonçalves-Ferreira, A. (2012) · Surgical and Radiologic Anatomy · doi:10.1007/s00276-012-0979-y · Cited by 105 · see citing works
Volumes, spatial extents and a probabilistic atlas of the human basal ganglia and thalamus
Ahsan, R. L., Allom, R. J., Gousias, I. S., Habib, H., Turkheimer, F., Free, S. L., Lemieux, L., Myers, R., Duncan, J. S., & Brooks, D. J. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.06.004 · Cited by 102 · see citing works
Target‐Specific Glutamatergic Regulation of Dopamine Neurons in the Ventral Tegmental Area
Takahata, R., & Moghaddam, B. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0751775.x · Cited by 101 · see citing works
Diversity and Homogeneity in Responses of Midbrain Dopamine Neurons
Fiorillo, C. D., Yun, S. R., & Song, M. R. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3886-12.2013 · Cited by 99 · see citing works
Direct visualization of the subthalamic nucleus and its iron distribution using high‐resolution susceptibility mapping
Andreas Schäfer, A., Forstmann, B. U., Neumann, J., Wharton, S., Mietke, A., Bowtell, R. W., & Turner, R. (2011) · Human Brain Mapping · doi:10.1002/hbm.21404 · Cited by 96 · see citing works
High resolution single-shot EPI at 7T
Speck, O., Stadler, J., & Zaitsev, M. (2007) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-007-0087-x · Cited by 95 · see citing works
Self-citation
The role of the pedunculopontine tegmental nucleus in relation to conditioned motor performance in the cat
Dormont, J. F., Condé, H., & Farin, D. (1998) · Experimental Brain Research · doi:10.1007/s002210050474 · Cited by 92 · see citing works
Learning-Related Human Brain Activations Reflecting Individual Finances
Tobler, P. N., Fletcher, P. C., Bullmore, E. T., & Schultz, W. (2007) · Neuron · doi:10.1016/j.neuron.2007.03.004 · Cited by 85 · see citing works
Elevated endogenous GABA level correlates with decreased fMRI signals in the rat brain during acute inhibition of GABA transaminase
Chen, Z., Silva, A. C., Yang, J., & Shen, J. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20364 · Cited by 83 · see citing works
Mesolimbic novelty processing in older adults.
Bunzeck, N., Schütze, H., Stallforth, S., Kaufmann, J., Düzel, S., Heinze, H., & Düzel, E. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm020 · Cited by 79 · see citing works
Self-citation
The locus coeruleus noradrenergic system in the rat brain studied by dual-probe microdialysis
van Gaalen, M. M., Kawahara, H., Kawahara, Y., & Westerink, B. H. C. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00416-2 · Cited by 77 · see citing works
Automated Brainstem Co-registration (ABC) for MRI
Napadow, V., Dhond, R. P., Kennedy, D. N., Hui, K. K. S., & Makris, N. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.05.050 · Cited by 76 · see citing works
Comment on “Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI” and “Homeostatic Sleep Pressure and Responses to Sustained Attention in the Suprachiasmatic Area”
Astafiev, S. V., Snyder, A. Z., Shulman, G. L., & Corbetta, M. (2010) · Science · doi:10.1126/science.1177200 · Cited by 72 · see citing works
Sources of the Increased Longitudinal Relaxation Rates Observed in Melanotic Melanoma An In Vitro Study of Synthetic Melanins
ENOCHS, W., HYSLOP, W., BENNETT, H., et al. (1989) · Investigative Radiology · doi:10.1097/00004424-198910000-00014 · Cited by 72 · see citing works
Multiparametric brainstem segmentation using a modified multivariate mixture of Gaussians
Lambert, C., Lutti, A., Helms, G., Frackowiak, R. S. J., & Ashburner, J. (2013) · NeuroImage Clinical · doi:10.1016/j.nicl.2013.04.017 · Cited by 71 · see citing works
Parcellation of the human substantia nigra based on anatomical connectivity to the striatum
Chowdhury, R., Lambert, C., Dolan, R. J., & Düzel, E. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.05.043 · Cited by 70 · see citing works
Self-citation
Highly accelerated PSF-mapping for EPI distortion correction with improved fidelity
In, M., & Speck, O. (2011) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-011-0275-6 · Cited by 65 · see citing works
Self-citation
Positive or negative blips? The effect of phase encoding scheme on susceptibility-induced signal losses in EPI
Panfilis, C. D., & Schwarzbauer, C. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.11.014 · Cited by 64 · see citing works
Assessment of human brain motion using CSPAMM
Soellinger, M., Ryf, S., Boesiger, P., et al. (2007) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.20882 · Cited by 46 · see citing works
Identification and characterisation of midbrain nuclei using optimised functional magnetic resonance imaging
Limbrick‐Oldfield, E. H., Brooks, J. C. W., Wise, R. G., Padormo, F., Hajnal, J. V., Beckmann, C. F., & Ungless, M. A. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.08.016 · Cited by 46 · see citing works
Diffusion-based spatial priors for functional magnetic resonance images
Harrison, L. M., Penny, W. D., Jean Daunizeau, A., & Friston, K. J. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.02.005 · Cited by 45 · see citing works
Structural integrity of the substantia nigra and subthalamic nucleus predicts flexibility of instrumental learning in older-age individuals
Chowdhury, R., Guitart‐Masip, M., Lambert, C., Dolan, R. J., & Düzel, E. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.03.030 · Cited by 42 · see citing works
Self-citation
Surgical anatomy of the pedunculopontine and peripeduncular nuclei
Zrinzo, L. U., Zrinzo, L. V., Zrinzo, L. V., et al. (2008) · British Journal of Neurosurgery · doi:10.1080/02688690802448426 · Cited by 30 · see citing works
Assessing nigrostriatal dysfunctions by pharmacological MRI in parkinsonian rhesus macaques
Zhang, Z., Andersen, A. H., Ai, Y., Loveland, A., Hardy, P., Gerhardt, G. A., & Gash, D. M. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.07.004 · Cited by 30 · see citing works
Bilateral nigral 6-hydroxydopamine lesions increase the amount of extracellular dopamine in the nucleus accumbens
van Oosten, R. V., Verheij, M. M. M., & Cools, A. R. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.09.004 · Cited by 18 · see citing works
Neurophysiology: The Brain at Work
Friston, K. J. (2008) · Current Biology · doi:10.1016/j.cub.2008.03.042 · Cited by 12 · see citing works
Optimized EPI for fMRI using a slice-dependent template-based gradient compensation method to recover local susceptibility-induced signal loss
Rick, J., Speck, O., Maier, S. J., et al. (2010) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-010-0215-x · Cited by 11 · see citing works
Self-citation
Response to Comment on “Homeostatic Sleep Pressure and Responses to Sustained Attention in the Suprachiasmatic Area”
Schmidt, C., Peigneux, P., Maquet, P., & Phillips, C. L. M. (2010) · Science · doi:10.1126/science.1177949 · Cited by 9 · see citing works
Diagnostic evaluation of the substantia nigra
McRitchiet, D. A., Halliday, G. M., & Pamphlett, R. (1996) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1996.tb00898.x · Cited by 5 · see citing works
Diagnostic evaluation of the substantia nigra
McRitchie, D. A., Halliday, G. M., & Pamphlett, R. (1996) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.1996.4698046.x · Cited by 5 · see citing works
Untitled work
Glover (2000) · doi:10.1002/1522-2594(200007)44:1

Flagged first, then by citations

Sorted by citations

Acute social isolation evokes midbrain craving responses similar to hunger
Tomova, L., Wang, K. L., Thompson, T., Matthews, G. A., Takahashi, A., Tye, K. M., & Saxe, R. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-00742-z · Cited by 283 · see citing works

Authors: Düzel, E., Guitart-Masip, M., Maass, A., Hämmerer, D., Betts, M. J., Speck, O., Weiskopf, N., & Kanowski, M.
Affiliations: University College London (GB)
Otto-von-Guericke-Universität Magdeburg (DE)
Wellcome Centre for Human Neuroimaging (GB)
Corresponding author: Düzel, Emrah
ORCID: Düzel, Emrah
Maass, Anne
Hämmerer, Dorothea
Betts, Matthew J.
Speck, Oliver
Weiskopf, Nikolaus
Venue: Biological Magnetic Resonance
Publisher: Springer US
Published: 2015
Pages: 581-609
ISSN: 0192-6020 (ISSN-L)
DOI: 10.1007/978-1-4899-7591-1_20
OpenAlex: W2262716280
Cited by: 16
References: 128
Citations by year: 2026: 1 · 2024: 1 · 2022: 1 · 2021: 1 · 2020: 5 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 1
FWCI: 11.24
Type: book chapter
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Biological magnetic resonance (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
MPG.PuRe (Max Planck Society) (submittedVersion)
Topics: Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
Keywords: midbrain, passive optical networks, functional MRI, neurotransmitter systems, brain activity imaging, neurological disorders, neuropsychiatric disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Midbrain fMRI: Applications, Limitations and Challenges

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks