Cited by 487Sleep and Wakefulness ResearchSleep and Work-Related FatigueCircadian rhythm and melatonin

Physiological Correlates of Prolonged Sleep Deprivation in Rats

Rechtschaffen, Allan, Gilliland, Marcia A., Bergmann, Bernard M., Winter, Jacqueline B.·1983·Science

Abstract

The issue of whether sleep is physiologically necessary has been unresolved because experiments that reported deleterious effects of sleep deprivation did not control for the stimuli used to prevent sleep. In this experiment, however, experimental and control rats received the same relatively mild physical stimuli, but stimulus presentations were timed to reduce sleep severely in experimental rats but not in controls. Experimental rats suffered severe pathology and death; control rats did not.

Integrity signals

Registry

Crossref · 10.1126/science.6857280

Cites

16 of 16 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Sleep deprivation of rats is lethal after approximately 2-3 weeks.

    “Later studies using more controlled approaches found that sleep deprivation of rats is lethal after ~2–3 wk (459)”

    From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [459]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Rechtschaffen, A., Gilliland, M. A., Bergmann, B. M., & Winter, J. B.
Affiliations
University of Chicago (US)
Venue
Science
Published
1983-07-08
Volume
221
Issue
4606
Pages
182-184
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2073264303
Cited by
487
References
16
Citations by year
2026: 12 · 2025: 24 · 2024: 14 · 2023: 15 · 2022: 11 · 2021: 12 · 2020: 13 · 2019: 15 · 2018: 14 · 2017: 18 · 2016: 19 · 2015: 17 · 2014: 14 · 2013: 19 · 2012: 24
FWCI
3.87
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Keywords
sleep deprivation, physical stimuli, sleep pathology
MeSH terms
Adrenal Glands, Animals, Body Weight, Electroencephalography, Male, Organ Size, Rats, Inbred Strains, Sleep Deprivation, Time Factors, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review