Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

Arnold, K., Bordoli, L., Kopp, J., & Schwede, T. F. (2005) · Bioinformatics · doi:10.1093/bioinformatics/bti770 · Cited by 6,951 · see citing works

Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America

Pappas, P. G., Kauffman, C. A., Andes, D., Benjamin, D. K., Calandra, T. F., Edwards, J. E., Filler, S. G., Fisher, J. F., Kullberg, B.-J., Zeichner, L. O., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/596757 · Cited by 3,191 · see citing works

Multiple sequence alignment with Clustal X

Jeanmougin, F., Thompson, J. D., Gouy, M., Higgins, D. G., & Gibson, T. J. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01285-7 · Cited by 2,652 · see citing works

The SWISS-MODEL Repository and associated resources

Kiefer, F., Arnold, K., Künzli, M., Bordoli, L., & Schwede, T. F. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn750 · Cited by 2,003 · see citing works

Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment

Pfaller, M. A. (2012) · The American Journal of Medicine · doi:10.1016/j.amjmed.2011.11.001 · Cited by 903 · see citing works

Protein Modeling by E-mail

Peitsch, M. C. (1995) · Nature Biotechnology · doi:10.1038/nbt0795-658 · Cited by 814 · see citing works

Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

Sanglard, D., & Odds, F. C. (2002) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(02)00181-0 · Cited by 784 · see citing works

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-Year Analysis of Susceptibilities of <i>Candida</i> Species to Fluconazole and Voriconazole as Determined by CLSI Standardized Disk Diffusion

Pfaller, M. A., Diekema, D. J., Gibbs, D. L., Newell, V. A., Ellis, D., Tullio, V., Rodloff, A., Fu, W., & Ling, T. A. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.02117-09 · Cited by 718 · see citing works

Clinical Practice Guidelines for the Management of Candidiasis: 2009 Update by the Infectious Diseases Society of America

Parczewska, O. K., Posaconazol, przeciwgrzybicze, L., Anidulafungina, Micafungina, & wrażliwość, O. (2009) · Cited by 656 · see citing works

Crystal structure of cytochrome P450 14α-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

Podust, L. M., Poulos, T. L., & Waterman, M. R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061562898 · Cited by 534 · see citing works

Epidemiology of Candidemia in Brazil: a Nationwide Sentinel Surveillance of Candidemia in Eleven Medical Centers

Colombo, A. L., Nucci, M., Park, B. J., Nouér, S. A., Arthington, B. A., da Matta, D. A., Warnock, D. W., & Morgan, J. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.00773-06 · Cited by 525 · see citing works

Assessing protein structures with a non-local atomic interaction energy

Melo, F., & Feytmans, E. (1998) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.1665 · Cited by 505 · see citing works

Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in <i>Candida albicans</i> Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients

Perea, S., López-Ribot, J. L., Kirkpatrick, W. R., McAtee, R. K., Santillán, R. A., Martı́nez, M., Calabrese, D., Sanglard, D., & Patterson, T. F. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.10.2676-2684.2001 · Cited by 470 · see citing works

Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents

Sanglard, D., Ischer, F., Koymans, L. M. H., & Billé, J. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.2.241 · Cited by 465 · see citing works

EUCAST technical note on the EUCAST definitive document EDef 7.2: method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST)

Arendrup, M. C., Cuenca-Estrella, M., Lass-Flörl, C., & Hope, W. (2012) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2012.03880.x · Cited by 451 · see citing works

Molecular basis of resistance to azole antifungals.

Lupetti, A. (2002) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(02)02280-3 · Cited by 449 · see citing works

Galleria mellonella as a Model System To Study Cryptococcus neoformans Pathogenesis

Mylonakis, E. E., Moreno, R., Khoury, J. B. E., Idnurm, A., Heitman, J., Calderwood, S. B., Ausubel, F. M., & Diener, A. C. (2005) · Infection and Immunity · doi:10.1128/iai.73.7.3842-3850.2005 · Cited by 432 · see citing works

<i>Candida albicans</i> Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents

Sanglard, D., Ischer, F., Parkinson, T., Falconer, D., & Bille, J. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.8.2404-2412.2003 · Cited by 398 · see citing works

Contribution of mutations in the cytochrome P450 14α-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans

Marichal, P., Koymans, L., Willemsens, S., Bellens, D., Verhasselt, P., Luyten, W., Borgers, M., Ramaekers, F. C. S., Odds, F. C., & Vanden Bossche, H. (1999) · Microbiology · doi:10.1099/00221287-145-10-2701 · Cited by 382 · see citing works

Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens

Kavanagh, K. A., & Reeves, E. P. (2003) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2003.09.002 · Cited by 381 · see citing works

Candida tropicalis: its prevalence, pathogenicity and increasing resistance to fluconazole

Kothavade, R. J., Kura, M. M., Valand, A. G., & Panthaki, M. H. (2010) · Journal of Medical Microbiology · doi:10.1099/jmm.0.013227-0 · Cited by 340 · see citing works

Mode of Action and Resistance to Azole Antifungals Associated with the Formation of 14α-Methylergosta-8,24(28)-dien-3β,6α-diol

Kelly, S. L., Lamb, D. C., Corran, A. J., Baldwin, B. C., & Kelly, D. E. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1272 · Cited by 296 · see citing works

Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature

Morio, F., Loge, C., Besse, B., Hennequin, C., & Le Pape, P. (2010) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.11.006 · Cited by 279 · see citing works

Candida bloodstream infections: comparison of species distribution and resistance to echinocandin and azole antifungal agents in intensive care unit (ICU) and non-ICU settings in the SENTRY antimicrobial surveillance program (2008–2009)

Pfaller, M. A., Messer, S. A., Moet, G. J., Jones, R. N., & Castanheira, M. (2011) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2011.02.016 · Cited by 274 · see citing works

Structural Basis of Human CYP51 Inhibition by Antifungal Azoles

Strushkevich, N. V., Usanov, S. A., & Park, H. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.01.075 · Cited by 273 · see citing works

Three-Dimensional Models of Wild-Type and Mutated Forms of Cytochrome P450 14α-Sterol Demethylases from Aspergillus fumigatus and Candida albicans Provide Insights into Posaconazole Binding

Li, X., Madison, V., Chau, A. S., Loebenberg, D., Palermo, R. E., & McNicholas, P. M. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.2.568-574.2004 · Cited by 266 · see citing works

Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens

Becher, R., & Wirsel, S. G. R. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4195-9 · Cited by 247 · see citing works

Wax moth larva (Galleria mellonella): an in vivo model for assessing the efficacy of antistaphylococcal agents

Desbois, A. P., & Coote, P. J. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr198 · Cited by 219 · see citing works

A mutation in the 14 alpha-demethylase gene of Uncinula necator that correlates with resistance to a sterol biosynthesis inhibitor

Délye, C., Laigret, F., & Corio‐Costet, M. (1997) · Applied and Environmental Microbiology · doi:10.1128/aem.63.8.2966-2970.1997 · Cited by 216 · see citing works

Detection of amphotericin B-resistant Candida isolates in a broth-based system

Rex, J. H., Cooper, C. R., Merz, W. G., Galgiani, J. N., & Anaissie, E. J. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.4.906 · Cited by 198 · see citing works

Application of Real-Time Quantitative PCR to Molecular Analysis of Candida albicans Strains Exhibiting Reduced Susceptibility to Azoles

Chau, A. S., Mendrick, C. A., Sabatelli, F. J., Loebenberg, D., & McNicholas, P. M. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.6.2124-2131.2004 · Cited by 187 · see citing works

Diethylcarbamazine-related antimicrobial activity in Mycobacterium tuberculosis-infected blood

Kitchen, L. W. (1998) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/42.2.241 · Cited by 183 · see citing works

Identification and Characterization of Four Azole-Resistant <i>erg3</i> Mutants of <i>Candida albicans</i>

Martel, C. M., Parker, J. E., Bader, O., Weig, M., Gross, U., Warrilow, A. G. S., Rolley, N., Kelly, D. E., & Kelly, S. L. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00348-10 · Cited by 168 · see citing works

Ergosterol biosynthesis pathway in Aspergillus fumigatus

Alcázar‐Fuoli, L., Mellado, E., García‐Effrón, G., López, J. F., Grimalt, J. O., Cuenca-Estrella, J. M., & Rodrı́guez-Tudela, J. L. (2007) · Steroids · doi:10.1016/j.steroids.2007.11.005 · Cited by 163 · see citing works

Rhodamine 6G efflux for the detection of CDR1-overexpressing azole-resistant Candidaalbicans strains

Maesaki, S., Marichal, P., Bossche, H. V., Sanglard, D., & Kohno, S. (1999) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/44.1.27 · Cited by 162 · see citing works

Epidemiology, species distribution and in vitro antifungal susceptibility of fungaemia in a Spanish multicentre prospective survey

Pemán, J., Cantón, R., Quindós, G., Eraso, E., Alcoba-Flórez, J., Guinea, J., Merino, P., Ruiz-Pérez-de-Pipaon, M. T., del Molino, L. P., Linares-Sicilia, M. J., et al. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks019 · Cited by 159 · see citing works

Comparison of Visual and Spectrophotometric Methods of Broth Microdilution MIC End Point Determination and Evaluation of a Sterol Quantitation Method for In Vitro Susceptibility Testing of Fluconazole and Itraconazole against Trailing and Nontrailing <i>Candida</i> Isolates

Arthington-Skaggs, B. A., Lee-Yang, W., Ciblak, M. A., Frade, J. P., Brandt, M. E., Hajjeh, R. A., Harrison, L. H., Sofair, A. N., & Warnock, A. D. W. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.8.2477-2481.2002 · Cited by 158 · see citing works

Mechanisms of azole resistance in 52 clinical isolates of Candida tropicalis in China

Jiang, C., Dong, D., Yu, B., Cai, G., Wang, X., Ji, Y., & Peng, Y. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks481 · Cited by 153 · see citing works

Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile

Scorzoni, L., de Lucas, M. P., Mesa-Arango, A. C., Fusco‐Almeida, A. M., Lozano, E., Cuenca‐Estrella, M., Mendes‐Giannini, M. J. S., & Zaragoza, Ó. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060047 · Cited by 150 · see citing works

ESCMID guideline for the diagnosis and management of Candida diseases 2012: developing European guidelines in clinical microbiology and infectious diseases

Ullmann, A. J., Cornely, O. A., DonneNy, J. P., Akova, M., Arendrup, M. C., Arıkan-Akdağlı, S., Bassetti, M., Billé, J., Calandra, T., Castagnola, E., et al. (2012) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12037 · Cited by 150 · see citing works

Experimental Induction of Fluconazole Resistance in <i>Candida tropicalis</i> ATCC 750

Barchiesi, F., Calabrese, D., Sanglard, D., Falconi Di Francesco, L., Caselli, F., Giannini, D., Giacometti, A., Gavaudan, S., & Scalise, G. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.6.1578-1584.2000 · Cited by 145 · see citing works

Risk Factors forCandida tropicalisFungemia in Patients with Cancer

Kontoyiannis, D. P., Vaziri, I., Hanna, H. A., Boktour, M. R., Thornby, J. I., Hachem, R. Y., Bodey, G. P., & RAAD, I. I. (2001) · Clinical Infectious Diseases · doi:10.1086/323812 · Cited by 143 · see citing works

Mechanisms of Azole Resistance in a Clinical Isolate of Candida tropicalis

Vandeputte, P., Larcher, G., Bergès, T., Rénier, G., Chabasse, D., & Bouchara, J. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.11.4608-4615.2005 · Cited by 141 · see citing works

G484S Amino Acid Substitution in Lanosterol 14-α Demethylase ( <i>ERG11</i> ) Is Related to Fluconazole Resistance in a Recurrent <i>Cryptococcus neoformans</i> Clinical Isolate

Rodero, L., Mellado, E., Rodriguez, A. C., Salve, A., Guelfand, L., Cahn, P., Cuenca-Estrella, M., Davel, G., & Rodriguez-Tudela, J. L. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.11.3653-3656.2003 · Cited by 139 · see citing works

Pathogenicity of<i>Aspergillus fumigatus</i>mutants assessed in<i>Galleria mellonella</i>matches that in mice

Slater, J. L., Gregson, L., Denning, D. W., & Warn, P. A. (2011) · Medical Mycology · doi:10.3109/13693786.2010.523852 · Cited by 136 · see citing works

Recent experience with fungaemia: change in species distribution and azole resistance

Chakrabarti, A., Chatterjee, S. S., Rao, K. L. N., Zameer, M., Rudramurthy, S. M., Singhi, S. C., Singh, R., & Varma, S. C. (2009) · Scandinavian Journal of Infectious Diseases · doi:10.1080/00365540902777105 · Cited by 132 · see citing works

Insights into Candida tropicalis nosocomial infections and virulence factors

Negri, M., Silva, S., Henriques, M., & Oliveira, R. (2012) · European Journal of Clinical Microbiology &amp; Infectious Diseases · doi:10.1007/s10096-011-1455-z · Cited by 132 · see citing works

PCR cloning and detection of point mutations in the eburicol 14a-demethylase (CYP51) gene from Erysiphe graminis f. sp. hordei, a “recalcitrant” fungus

Délye, C., Bousset, L., & Corio‐Costet, M. (1998) · Current Genetics · doi:10.1007/s002940050413 · Cited by 131 · see citing works

Molecular Mechanisms of Drug Resistance in Clinical Candida Species Isolated from Tunisian Hospitals

Eddouzi, J., Parker, J. E., Vale-Silva, L. A., Coste, A., Ischer, F., Kelly, S., Manai, M., & Sanglard, D. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00555-13 · Cited by 128 · see citing works

Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen <i>Aspergillus fumigatus</i>

Yasmin, S., Alcazar-Fuoli, L., Gründlinger, M., Puempel, T., Cairns, T., Blatzer, M., Lopez, J. F., Grimalt, J. O., Bignell, E., & Haas, H. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106399108 · Cited by 126 · see citing works

Candida tropicalisin human disease

Chai, L. Y. A., Denning, D. W., & Warn, P. A. (2010) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2010.489506 · Cited by 126 · see citing works

The non-mammalian hostGalleria mellonellacan be used to study the virulence of the fungal pathogenCandida tropicalisand the efficacy of antifungal drugs during infection by this pathogenic yeast

Mesa-Arango, A. C., Forastiero, A., Bernal‐Martínez, L., Cuenca‐Estrella, M., Mellado, E., & Zaragoza, Ó. (2012) · Medical Mycology · doi:10.3109/13693786.2012.737031 · Cited by 122 · see citing works

Identification of a Cryptococcus neoformans Cytochrome P450 Lanosterol 14α-Demethylase (Erg11) Residue Critical for Differential Susceptibility between Fluconazole/Voriconazole and Itraconazole/Posaconazole

Sionov, E., Chang, Y. C., Garraffo, H. M., Dolan, M. A., Ghannoum, M. A., & Kwon-Chung, K. J. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05502-11 · Cited by 120 · see citing works

Amino acid substitutions in the Candida albicans sterol  5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence

Morio, F., Pagniez, F., Lacroix, C., Miegeville, M., & Le Pape, P. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks186 · Cited by 120 · see citing works

Patterns of Amphotericin B Killing Kinetics against Seven Candida Species

Cantón, E., Pemán, J., Gobernado, M., Viudes, A., & Espinel‐Ingroff, A. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.7.2477-2482.2004 · Cited by 119 · see citing works

The G464S amino acid substitution in Candida albicans sterol 14α-demethylase causes fluconazole resistance in the clinic through reduced affinity

Kelly, S. L., Lamb, D. C., Loeffler, J., Einsele, H., & Kelly, D. E. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1136 · Cited by 116 · see citing works

Y132H substitution inCandida albicanssterol 14α-demethylase confers fluconazole resistance by preventing binding to haem

Kelly, S. L., Lamb, D. C., & Kelly, D. E. (1999) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1999.tb08792.x · Cited by 114 · see citing works

Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in <i>ERG11</i> and Exhibiting Cross-Resistance to Azoles and Amphotericin B

Hull, C. M., Parker, J. E., Bader, O., Weig, M., Gross, U., Warrilow, A. G. S., Kelly, D. E., & Kelly, S. L. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.06253-11 · Cited by 113 · see citing works

Legionella pneumophila Pathogenesis in the Galleria mellonella Infection Model

Harding, C. R., Schroeder, G. N., Reynolds, S. E., Kosta, A., Collins, J. W., Mousnier, A., & Frankel, G. M. (2012) · Infection and Immunity · doi:10.1128/iai.00510-12 · Cited by 107 · see citing works

Genetic Dissection of Azole Resistance Mechanisms in <i>Candida albicans</i> and Their Validation in a Mouse Model of Disseminated Infection

MacCallum, D. M., Coste, A., Ischer, F., Jacobsen, M. D., Odds, F. C., & Sanglard, D. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01645-09 · Cited by 98 · see citing works

Analysis of the CYP51 gene and encoded protein in propiconazole‐resistant isolates of Mycosphaerella fijiensis

Cañas-Gutiérrez, G. P., Angarita, M., Restrepo-Flórez, J. M., Rodríguez, P., Herrera, C. X. M., & Arango, R. (2009) · Pest Management Science · doi:10.1002/ps.1770 · Cited by 86 · see citing works

Molecular Modelling of the Emergence of Azole Resistance in Mycosphaerella graminicola

Mullins, J. G. L., Parker, J. E., Cools, H. J., Togawa, R. C., Lucas, J. A., FRAAIJE, B. A., Kelly, D. E., & Kelly, S. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020973 · Cited by 85 · see citing works

Selecting an Invertebrate Model Host for the Study of Fungal Pathogenesis

Desalermos, A. P., Fuchs, B. B., & Mylonakis, E. E. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002451 · Cited by 81 · see citing works

Species distribution and anti-fungal susceptibility of Candidaemia at a multi super-specialty center in southern India

Adhikary, R., & Joshi, S. (2011) · Indian Journal of Medical Microbiology · doi:10.4103/0255-0857.83920 · Cited by 68 · see citing works

Susceptibilities to amphotericin B and fluconazole of Candida species in Taiwan Surveillance of Antimicrobial Resistance of Yeasts 2006

Yang, Y.-L., Wang, A.-H., Wang, C., Cheng, W.-T., Li, S., & Lo, H. (2008) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2008.01.011 · Cited by 66 · see citing works

A single amino acid substitution converts cytochrome P45014DM to an inactive form, cytochrome P450SG1: Complete primary structures deduced from cloned DNAs

Ishida, N., Aoyama, Y., Hatanaka, R., Oyama, Y., Imajo, S., Ishiguro, M., Oshima, T., Nakazato, H., Noguchi, T., Maitra, U. S., et al. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)81087-8 · Cited by 65 · see citing works

Molecular Mechanisms of Itraconazole Resistance in Candida dubliniensis

Pinjon, E., Moran, G. P., Jackson, C. J., Kelly, S. L., Sanglard, D., Coleman, D. C., & Sullivan, D. J. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.8.2424-2437.2003 · Cited by 63 · see citing works

Antibacterial agents: back to the future? Can we live with only colistin, co-trimoxazole and fosfomycin?

Carlet, J. M., & Mainardi, J. (2011) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03702.x · Cited by 61 · see citing works

EUCAST technical note on anidulafungin

Arendrup, M. C., Rodriguez-Tudela, J. L., Lass‐Flörl, C., Cuenca‐Estrella, M., Donnelly, J. P., & Hope, W. W. (2011) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03647.x · Cited by 60 · see citing works

Resistance to Voriconazole Due to a G448S Substitution in Aspergillus fumigatus in a Patient with Cerebral Aspergillosis

Peláez, T., Gijón, P., Bunsow, E., Bouza, E., Sánchez-Yebra, W., Valerio, M., Gama, B., Cuenca‐Estrella, M., & Mellado, E. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.00329-12 · Cited by 51 · see citing works

EUCAST technical note on Amphotericin B

Lass-Flörl, C., Arendrup, M. C., Rodriguez-Tudela, J.-L., Cuenca-Estrella, M., Donnelly, P., & Hope, W. (2011) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03644.x · Cited by 49 · see citing works

Fusarium pathogenesis investigated using Galleria mellonella as a heterologous host

Coleman, J. J., Muhammed, M., Kasperkovitz, P. V., Vyas, J. M., & Mylonakis, E. E. (2011) · Fungal Biology · doi:10.1016/j.funbio.2011.09.005 · Cited by 49 · see citing works

Fluconazole Treatment Is Effective against a Candida albicans erg3/erg3 Mutant In Vivo Despite In Vitro Resistance

Miyazaki, T., Miyazaki, Y., Izumikawa, K., Kakeya, H., Miyakoshi, S., Bennett, J. E., & Kohno, S. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.50.2.580-586.2006 · Cited by 49 · see citing works

Ergosterol biosynthesis in novel melanized fungi from hypersaline environments

Méjanelle, L., López, J. F., Gunde‐Cimerman, N., & Grimalt, J. O. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31658-8 · Cited by 46 · see citing works

Editorial

Raoult, D. (2012) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2012.03915.x · Cited by 38 · see citing works

Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic malignancies.

Myoken, Y., Kyo, T., Fujihara, M., Sugata, T., & Mikami, Y. (2004) · PubMed · Cited by 31 · see citing works

Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans

Park, H., Lee, I., Chun, Y., Yun, C., Johnston, J. B., de Montellano, P. R. O., & Kim, D. (2011) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2011.02.002 · Cited by 25 · see citing works

Y132H substitution in Candida albicans sterol 14α-demethylase confers fluconazole resistance by preventing binding to haem

Kelly, S. L. (1999) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(99)00478-4 · Cited by 21 · see citing works

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

Ponte‐Sucre, A., Gamarro, F., Dujardin, J., Barrett, M. P., López‐Vélez, R., García‐Hernández, R., Pountain, A. W., Mwenechanya, R., & Papadopoulou, B. (2017) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006052 · Cited by 971 · see citing works

An Update on Candida tropicalis Based on Basic and Clinical Approaches

Zuza-Alves, D. L., Rocha, W. P. D. S., & Chaves, G. M. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01927 · Cited by 305 · see citing works

The Production of Reactive Oxygen Species Is a Universal Action Mechanism of Amphotericin B against Pathogenic Yeasts and Contributes to the Fungicidal Effect of This Drug

Mesa-Arango, A. C., Trevijano-Contador, N., Román, E., Sánchez-Fresneda, R., Casas, C., Herrero, E., Argüelles, J. C., Pla, J., Cuenca-Estrella, M., & Zaragoza, O. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03570-14 · Cited by 232 · see citing works

Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens

Ksiezopolska, E., & Gabaldón, T. (2018) · Genes · doi:10.3390/genes9090461 · Cited by 230 · see citing works

Fungal Cell Wall: Emerging Antifungals and Drug Resistance.

Lima, S. L., Colombo, A. L., & de Almeida Junior, J. N. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02573 · Cited by 223 · see citing works

SUSCEPTIBILITY TEST FOR FUNGI: CLINICAL AND LABORATORIAL CORRELATIONS IN MEDICAL MYCOLOGY

Alastruey‐Izquierdo, A., Melhem, M. D. S. C., Bonfietti, L. X., & Rodriguez-Tudela, J. L. (2015) · Revista do Instituto de Medicina Tropical de São Paulo · doi:10.1590/s0036-46652015000700011 · Cited by 184 · see citing works

Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

Gonçalves, S. S., Souza, A. C. R., Chowdhary, A., Meis, J. F. G. M., & Colombo, A. L. (2016) · Mycoses · doi:10.1111/myc.12469 · Cited by 182 · see citing works

New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics

Geddes‐McAlister, J., & Shapiro, R. S. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13739 · Cited by 159 · see citing works

The Quiet and Underappreciated Rise of Drug-Resistant Invasive Fungal Pathogens

Arastehfar, A., Lass-Flörl, C., Garcia-Rubio, R., Daneshnia, F., Ilkit, M., Boekhout, T., Gabaldon, T., & Perlin, D. S. (2020) · Journal of Fungi · doi:10.3390/jof6030138 · Cited by 145 · see citing works

Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Monk, B. C., Sagatova, A. A., Hosseini, P., Ruma, Y. N., Wilson, R. K., & Keniya, M. V. (2019) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2019.02.008 · Cited by 136 · see citing works

Candida glabrata Biofilms: How Far Have We Come?

Rodrigues, C., Rodrigues, M., Silva, S., & Henriques, M. (2017) · Journal of Fungi · doi:10.3390/jof3010011 · Cited by 129 · see citing works

Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms and <i>In Vivo</i> Impact in Infected Galleria mellonella Larvae

Souza, A. C. R., Fuchs, B. B., Pinhati, H. M. S., Siqueira, R. A., Hagen, F., Meis, J. F., Mylonakis, E., & Colombo, A. L. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01177-15 · Cited by 121 · see citing works

Current status of antifungal resistance and its impact on clinical practice

Alcázar‐Fuoli, L., & Mellado, E. (2014) · British Journal of Haematology · doi:10.1111/bjh.12896 · Cited by 118 · see citing works

Molecular mechanisms of fluconazole resistance in Candida parapsilosis isolates from a U.S. surveillance system

Grossman, N. T., Pham, C. D., Cleveland, A. A., & Lockhart, S. R. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.04613-14 · Cited by 112 · see citing works

Multilaboratory study of epidemiological cutoff values for detection of resistance in eight Candida species to fluconazole, posaconazole, and voriconazole

Espinel-Ingroff, A., Pfaller, M. A., Bustamante, B., Canton, E., Fothergill, A., Fuller, J., Gonzalez, G. M., Lass-Flörl, C., Lockhart, S. R., Martin-Mazuelos, E., et al. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02615-13 · Cited by 105 · see citing works

Analysis of global antifungal surveillance results reveals predominance of Erg11 Y132F alteration among azole-resistant Candida parapsilosis and Candida tropicalis and country-specific isolate dissemination

Castanheira, M., Deshpande, L. M., Messer, S. A., Rhomberg, P. R., & Pfaller, M. A. (2019) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2019.09.003 · Cited by 105 · see citing works

Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi

Parente-Rocha, J. A., Bailão, A. M., Amaral, A. C., Taborda, C. P., Paccez, J. D., Borges, C. L., & Pereira, M. (2017) · Mediators of Inflammation · doi:10.1155/2017/9870679 · Cited by 93 · see citing works

Molecular mechanisms of azole resistance in Candida tropicalis isolates causing invasive candidiasis in China

Fan, X., Xiao, M., Zhang, D., Huang, J.-J., Wang, H., Hou, X., Zhang, L., Kong, F., Chen, S. C.-A., Tong, Z., et al. (2018) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2018.11.007 · Cited by 99 · see citing works

Galleria mellonella for the Evaluation of Antifungal Efficacy against Medically Important Fungi, a Narrative Review

Jemel, S., Guillot, J., Kallel, K., Botterel, F., & Dannaoui, É. (2020) · Microorganisms · doi:10.3390/microorganisms8030390 · Cited by 94 · see citing works

Facilitators of adaptation and antifungal resistance mechanisms in clinically relevant fungi

Hokken, M., Zwaan, B. J., Melchers, W. J. G., & Verweij, P. E. (2019) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2019.103254 · Cited by 94 · see citing works

Drug resistance mechanisms and their regulation in non- albicans Candida species

Kołaczkowska, A., & Kołaczkowski, M. (2016) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv445 · Cited by 88 · see citing works

Cell Wall changes in amphotericin B-resistant strains from Candida tropicalis and relationship with the immune responses elicited by the host

Mesa-Arango, A. C., Rueda, C., Román, E., Quintin, J., Terrón, M. C., Luque, D., Netea, M. G., Pla, J., & Zaragoza, O. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02681-15 · Cited by 86 · see citing works

Antifungal drug resistance in Candida species

Morace, G., Perdoni, F., & Borghi, E. (2014) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2014.09.002 · Cited by 80 · see citing works

Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical implications

Rogers, T. R., Verweij, P. E., Castanheira, M., Dannaoui, E., White, P. L., Arendrup, M. C., Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST), Arendrup, M. C., Arikan-Akdagli, S., Barchiesi, F., et al. (2022) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkac161 · Cited by 82 · see citing works

Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens

Rosam, K., Monk, B. C., & Lackner, M. (2020) · Journal of Fungi · doi:10.3390/jof7010001 · Cited by 78 · see citing works

The emerging threat antifungal-resistant Candida tropicalis in humans, animals, and environment

Lima, R., Ribeiro, F. D. C., Colombo, A. L., & de Almeida, J. N. (2022) · Frontiers in Fungal Biology · doi:10.3389/ffunb.2022.957021 · Cited by 78 · see citing works

Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Methods

Espinel‐Ingroff, A., Turnidge, J. D., Alastruey‐Izquierdo, A., Botterel, F., Cantón, R., Castro, C., Chen, Y., Chen, Y., Chryssanthou, E., Dannaoui, É., et al. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01651-18 · Cited by 74 · see citing works

Galleria mellonella: An invertebrate model to study pathogenicity in correctly defined fungal species

Binder, U., Maurer, E., & Lass‐Flörl, C. (2015) · Fungal Biology · doi:10.1016/j.funbio.2015.06.002 · Cited by 72 · see citing works

Fluconazole‐resistant Candida parapsilosis strains with a Y132F substitution in the ERG11 gene causing invasive infections in a neonatal unit, South Africa

Magobo, R. E., Lockhart, S. R., & Govender, N. P. (2020) · Mycoses · doi:10.1111/myc.13070 · Cited by 70 · see citing works

Resistance Mechanisms and Clinical Features of Fluconazole-Nonsusceptible Candida tropicalis Isolates Compared with Fluconazole-Less-Susceptible Isolates

Choi, M. J., Won, E. J., Shin, J. H., Kim, S. H., Lee, W. G., Kim, M., Lee, K., Shin, M., Suh, S., Ryang, D. W., et al. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02652-15 · Cited by 69 · see citing works

A One Health approach to overcoming fungal disease and antifungal resistance

Woods, M., McAlister, J. A., & Geddes‐McAlister, J. (2023) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1610 · Cited by 68 · see citing works

Synergistic activity of magnolol with azoles and its possible antifungal mechanism against<i>Candida albicans</i>

Sun, L.-M., Liao, K., Liang, S., Yu, P.-H., & Wang, D.-Y. (2015) · Journal of Applied Microbiology · doi:10.1111/jam.12737 · Cited by 67 · see citing works

Understanding the mechanisms of resistance to azole antifungals in Candida species

Li, Y., Hind, C. K., Furner-Pardoe, J., Sutton, J. M., & Rahman, K. M. (2025) · JAC-Antimicrobial Resistance · doi:10.1093/jacamr/dlaf106 · Cited by 66 · see citing works

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens

Sharma, J., Rosiana, S., Razzaq, I., & Shapiro, R. S. (2019) · Journal of Fungi · doi:10.3390/jof5010017 · Cited by 64 · see citing works

MDR1 overexpression combined with ERG11 mutations induce high-level fluconazole resistance in Candida tropicalis clinical isolates

Jin, L., Cao, Z., Wang, Q., Wang, Y., Wang, X., Chen, H., & Wang, H. (2018) · BMC Infectious Diseases · doi:10.1186/s12879-018-3082-0 · Cited by 55 · see citing works

The effect of antifungal resistance development on the virulence of Candida species

Bohner, F., Papp, C., & Gácser, A. (2022) · FEMS Yeast Research · doi:10.1093/femsyr/foac019 · Cited by 62 · see citing works

Antifungal drug resistance in Candida: a special emphasis on amphotericin B

Ahmady, L., Gothwal, M., Mukkoli, M. M., & Bari, V. K. (2024) · Apmis · doi:10.1111/apm.13389 · Cited by 58 · see citing works

An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains

Salazar, S. B., Simões, R., Pedro, N. A., Pinheiro, M. J. F., Carvalho, M. F. N. N., & Mira, N. P. (2020) · Journal of Fungi · doi:10.3390/jof6010023 · Cited by 55 · see citing works

Candida tropicalis bloodstream infection: Incidence, risk factors and outcome in a population-based surveillance

Fernández‐Ruiz, M., Puig‐Asensio, M., Guinea, J., Almirante, B., Padilla, B., Almela, M., Díaz‐Martín, A., Rodríguez‐Baño, J., Cuenca‐Estrella, M., & Aguado, J. M. (2015) · Journal of Infection · doi:10.1016/j.jinf.2015.05.009 · Cited by 54 · see citing works

Lipid core nanoparticles as a broad strategy to reverse fluconazole resistance in multiple Candida species

Bianchin, M. D., Borowicz, S. M., Machado, G. D. R. M., Pippi, B., Guterres, S. S., Pohlmann, A. R., Fuentefría, A. M., & Külkamp‐Guerreiro, I. C. (2018) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2018.12.011 · Cited by 51 · see citing works

Unmasking the Amphotericin B Resistance Mechanisms in Candida haemulonii Species Complex

Silva, L. N., Oliveira, S. S. C., Magalhães, L. B., Andrade-Neto, V. V., Torres-Santos, E. C., de Carvalho, M. D. C., Pereira, M. D., Branquinha, M. H., & dos Santos, A. L. S. (2020) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.0c00117 · Cited by 49 · see citing works

Mechanisms of azole antifungal resistance in clinical isolates of Candida tropicalis

Paul, S., Shaw, D., Joshi, H. N., Singh, S., Chakrabarti, A., Rudramurthy, S. M., & Ghosh, A. K. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269721 · Cited by 47 · see citing works

Widespread amphotericin B-resistant strains of Aspergillus fumigatus in Hamilton, Canada

Ashu, E. E., Korfanty, G. A., Samarasinghe, H., Pum, N., You, M., Yamamura, D. L. R., & Xu, J. (2018) · Infection and Drug Resistance · doi:10.2147/idr.s170952 · Cited by 47 · see citing works

A Cyp51B Mutation Contributes to Azole Resistance in Aspergillus fumigatus

González-Jiménez, I., Lucio, J., Amich, J., Cuesta, I., Arroyo, R. S., Alcázar‐Fuoli, L., & Mellado, E. (2020) · Journal of Fungi · doi:10.3390/jof6040315 · Cited by 47 · see citing works

Role of Antifungal Combinations in Difficult to Treat Candida Infections

Vitale, R. G. (2021) · Journal of Fungi · doi:10.3390/jof7090731 · Cited by 49 · see citing works

Implications of the EUCAST Trailing Phenomenon in Candida tropicalis for the In Vivo Susceptibility in Invertebrate and Murine Models

Astvad, K. M. T., Sanglard, D., Delarze, E., Hare, R. K., & Arendrup, M. C. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01624-18 · Cited by 43 · see citing works

Novel point mutations in the ERG11 gene in clinical isolates of azole resistant Candida species

Silva, D. B. D. S., Rodrigues, L. M. C., Almeida, A. A. D., Oliveira, K. M. P. D., & Grisolia/, A. B. (2016) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/0074-02760150400 · Cited by 42 · see citing works

Antiproliferation of Berberine in Combination with Fluconazole from the Perspectives of Reactive Oxygen Species, Ergosterol and Drug Efflux in a Fluconazole-Resistant Candida tropicalis Isolate

Shao, J., Shi, G., Wang, T., Wu, D., & Wang, C. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01516 · Cited by 40 · see citing works

Blood and intra-abdominal <i>Candida</i> spp. from a multicentre study conducted in Madrid using EUCAST: emergence of fluconazole resistance in <i>Candida parapsilosis</i>, low echinocandin resistance and absence of <i>Candida auris</i>

Díaz-García, J., Gómez, A., Machado, M., Alcalá, L., Reigadas, E., Sánchez-Carrillo, C., Pérez-Ayala, A., Gómez-García De La Pedrosa, E., González-Romo, F., Cuétara, M. S., et al. (2022) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkac288 · Cited by 35 · see citing works

The yeast, the antifungal, and the wardrobe: a journey into antifungal resistance mechanisms of Candida tropicalis

de Oliveira, J. S., Pereira, V. S., Castelo‐Branco, D. D. S. C. M., Cordeiro, R. D. A., Sidrim, J. J. C., Brilhante, R. S. N., & Rocha, M. F. G. (2020) · Canadian Journal of Microbiology · doi:10.1139/cjm-2019-0531 · Cited by 38 · see citing works

Mechanisms of Azole Resistance and Trailing in Candida tropicalis Bloodstream Isolates

Chen, P., Chuang, Y., Wu, U., Sun, H., Wang, J., Sheng, W., Chen, Y., & Chang, S. (2021) · Journal of Fungi · doi:10.3390/jof7080612 · Cited by 32 · see citing works

Synthesis, activity, and docking studies of eugenol‐based glucosides as new agents against Candida sp.

Hipólito, T. M. M., Bastos, G. T. L., Barbosa, T. W. L., de Souza, T. B., Coelho, L. F. L., Dias, A. L. T., Camps, I., dos Santos, M. H., Dias, D. F., Franco, L. L., et al. (2018) · Chemical Biology & Drug Design · doi:10.1111/cbdd.13318 · Cited by 32 · see citing works

Dynamics of in vitro development of azole resistance in Candida tropicalis

Paul, S., Singh, S., Sharma, D., Chakrabarti, A., Rudramurthy, S. M., & Ghosh, A. K. (2020) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2020.04.018 · Cited by 32 · see citing works

Point Mutations in the 14-α Sterol Demethylase Cyp51A or Cyp51C Could Contribute to Azole Resistance in Aspergillus flavus

Lucio, J. L., González-Jiménez, I., Rivero-Menéndez, O., Alastruey‐Izquierdo, A., Peláez, T., Alcázar‐Fuoli, L., & Mellado, E. (2020) · Genes · doi:10.3390/genes11101217 · Cited by 31 · see citing works

Epidemiology of antifungal susceptibility: Review of literature

Hadrich, I., & Ayadi, M. A. (2018) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2018.04.011 · Cited by 29 · see citing works

Collateral sensitivity counteracts the evolution of antifungal drug resistance in Candida auris

Carolus, H., Sofras, D., Boccarella, G., Jacobs, S., Biriukov, V. V., Goossens, L., Chen, A., Vantyghem, I., Verbeeck, T., Pierson, S., et al. (2024) · Nature Microbiology · doi:10.1038/s41564-024-01811-w · Cited by 27 · see citing works

The role of metabolism in shaping enzyme structures over 400 million years

(2025) · doi:10.1038/s41586-025-09205-6 · Cited by 28 · see citing works

Anticandidal synergistic activity of Ocimum sanctum and fluconazole of azole resistance strains of clinical isolates

Zaidi, K. U., Shah, F., Parmar, R., & Thawani, V. (2018) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2018.04.004 · Cited by 26 · see citing works

Precise genome editing using a CRISPR-Cas9 method highlights the role of CoERG11 amino acid substitutions in azole resistance in Candida orthopsilosis

Morio, F., Lombardi, L., Binder, U., Logé, C., Robert, E., Grässle, D., Bodin, M., Lass‐Flörl, C., Butler, G., & Pape, P. L. (2019) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkz204 · Cited by 27 · see citing works

Silver diamine fluoride (SDF) used in childhood caries management has potent antifungal activity against oral Candida species

Fakhruddin, K. S., Egusa, H., Ngo, H. C., Panduwawala, C., Pesee, S., Venkatachalam, T., & Samaranayake, L. P. (2020) · BMC Microbiology · doi:10.1186/s12866-020-01776-w · Cited by 25 · see citing works

Characterization of Virulence Factors in Candida Species Causing Candidemia in a Tertiary Care Hospital in Bangkok, Thailand

Saiprom, N., Wongsuk, T., Oonanant, W., Sukphopetch, P., Chantratita, N., & Boonsilp, S. (2023) · Journal of Fungi · doi:10.3390/jof9030353 · Cited by 26 · see citing works

Insights into the Multi-Azole Resistance Profile in Candida haemulonii Species Complex

Silva, L. N., Ramos, L. S., de Oliveira, S. S. C., Magalhães, L. B., Squizani, E. D., Kmetzsch, L., Vainstein, M. H., Branquinha, M. H., & dos Santos, A. L. S. (2020) · Journal of Fungi · doi:10.3390/jof6040215 · Cited by 25 · see citing works

Caspofungin and Polymyxin B Reduce the Cell Viability and Total Biomass of Mixed Biofilms of Carbapenem-Resistant Pseudomonas aeruginosa and Candida spp.

Fernandes, L., Fortes, B. N., Lincopán, N., & Ishida, K. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.573263 · Cited by 24 · see citing works

Does the use of antifungal agents in agriculture and food foster polyene resistance development? A reason for concern

Dalhoff, A. (2017) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2017.10.024 · Cited by 23 · see citing works

Azole Resistance and ERG11 Mutation in Clinical Isolates of Candida tropicalis

Siqueira, A. C., Bernardi, G., Arend, L. N. V. S., Cordeiro, G. T., Rosolen, D., Berti, F. C. B., Ferreira, A. M. M., Vasconcelos, T. M., Neves, B. C., Rodrigues, L. S., et al. (2025) · Journal of Fungi · doi:10.3390/jof11010024 · Cited by 22 · see citing works

Acquired multi-azole resistance in Candida tropicalis during persistent urinary tract infection in a dog

Álvarez‐Pérez, S., García, M. E., Cutuli, M. T., Fermín, M. L., Daza, M. Á., Peláez, T., & Blanco, J. L. (2016) · Medical Mycology Case Reports · doi:10.1016/j.mmcr.2016.02.001 · Cited by 22 · see citing works

Research progress on the drug resistance mechanisms of Candida tropicalis and future solutions

Xiong, H., Zhao, R., Han, S., Liu, Z., Zhang, X., Jia, Z., Cui, J., Zhang, Y., & Wang, X. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1594226 · Cited by 22 · see citing works

Antifungal treatment strategies and their impact on resistance development in clinical settings

van Rhijn, N., & White, P. L. (2025) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkaf382 · Cited by 27 · see citing works

Transcription Factor ADS-4 Regulates Adaptive Responses and Resistance to Antifungal Azole Stress

Wang, K., Zhang, Z., Chen, X., Sun, X., Jin, C., Liu, H., & Li, S. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00542-15 · Cited by 21 · see citing works

Total Protein Profile and Drug Resistance inCandida albicansIsolated from Clinical Samples

Zaidi, K. U., Mani, A., Thawani, V., & Mehra, A. (2016) · Molecular Biology International · doi:10.1155/2016/4982131 · Cited by 21 · see citing works

Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi

Chen, X., Duan, H. D., Hoy, M. J., Koteva, K. K., Spitzer, M., Guitor, A. K., Puumala, E., Fiebig‐Comyn, A., Hu, G., Yiu, B., et al. (2025) · Cell · doi:10.1016/j.cell.2025.11.036 · Cited by 23 · see citing works

Water Quality, Heavy Metals, and Antifungal Susceptibility to Fluconazole of Yeasts from Water Systems

Caicedo-Bejarano, L. D., Osorio-Vanegas, L. S., Ramírez-Castrillón, M., Castillo, J. E., Martínez-Garay, C. A., & Chávez, M. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20043428 · Cited by 19 · see citing works

In Vitro Activity of Essential Oils Distilled from Colombian Plants against Candidaauris and Other Candida Species with Different Antifungal Susceptibility Profiles

Zapata-Zapata, C., Loaiza-Oliva, M., Pabón, M. C. M., Stashenko, E. E., & Mesa-Arango, A. C. (2022) · Molecules · doi:10.3390/molecules27206837 · Cited by 18 · see citing works

Analysis of CDR1 and MDR1 Gene Expression and ERG11 Substitutions in Clinical Candida tropicalis Isolates from Alexandria, Egypt

El‐Kholy, M. A., Helaly, G. F., Ghazzawi, E. F. E., El-Sawaf, G., & Shawky, S. M. (2023) · Brazilian Journal of Microbiology · doi:10.1007/s42770-023-01106-y · Cited by 18 · see citing works

The Effects of Tormentic Acid and Extracts from Callistemon citrinus on Candida albicans and Candida tropicalis Growth and Inhibition of Ergosterol Biosynthesis in Candida albicans

Bvumbi, C. W., Fru, G., Stevens, M. Y., Mombeshora, M., & Mukanganyama, S. (2021) · The Scientific World JOURNAL · doi:10.1155/2021/8856147 · Cited by 19 · see citing works

Antifungal Activity of Plant Secondary Metabolites on Candida albicans: An Updated Review

Khan, A., Moni, S. S., Ali, M., Mohan, S., Jan, H., Rasool, S., Kamal, M. A., Alshahrani, S., Halawi, M., & Alhazmi, H. A. (2023) · Current Molecular Pharmacology · doi:10.2174/1874467215666220304143332 · Cited by 17 · see citing works

Commercial Methods for Antifungal Susceptibility Testing of Yeasts: Strengths and Limitations as Predictors of Resistance

Espinel‐Ingroff, A. (2022) · Journal of Fungi · doi:10.3390/jof8030309 · Cited by 19 · see citing works

A clinical analysis of Candida tropicalis bloodstream infections associated with hematological diseases, and antifungal susceptibility: a retrospective survey

Yang, B., Wei, Z., Wu, M., Lai, Y., & Zhao, W. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1092175 · Cited by 17 · see citing works

Etest ECVs/ECOFFs for Detection of Resistance in Prevalent and Three Nonprevalent Candida spp. to Triazoles and Amphotericin B and Aspergillus spp. to Caspofungin: Further Assessment of Modal Variability

Espinel‐Ingroff, A., Sasso, M., Turnidge, J. D., Arendrup, M. C., Botterel, F., Bourgeois, N., Bouteille, B., Cantón, R., Cassaing, S., Dannaoui, É., et al. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01093-21 · Cited by 17 · see citing works

Diversity of Toxigenic Molds and Mycotoxins Isolated from Dairy Products: Antifungal Activity of Egyptian Marine Algae on Aspergillus and Candida Species

Ahmed, A. E., Al-Kahtani, M. A., El-Diasty, E. M., Ahmed, A. S., Saber, H., Abbas, A., Diab, H. M., AlShehri, M. A., El‐Mansi, A. A., & Hussein, M. A. (2020) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.14.1.23 · Cited by 16 · see citing works

Novel Sulfones with Antifungal Properties: Antifungal Activities and Interactions with Candida spp. Virulence Factors

Gizińska, M., Staniszewska, M., & Ochal, Z. (2018) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557518666180924121209 · Cited by 15 · see citing works

Resistance rates of non-albicans Candida infections in Taiwan after the revision of 2012 Clinical and Laboratory Standards Institute breakpoints

Hii, I.-M., Liu, C.-E., Lee, Y.-L., Liu, W., Wu, P.-F., Hsieh, M.-H., Ho, M., Chen, Y., & Wang, F. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s184884 · Cited by 15 · see citing works

ClCPI, a cysteine protease inhibitor purified from Cassia leiandra seeds has antifungal activity against Candida tropicalis by inducing disruption of the cell surface

Melo, I. R. S., Dias, L. P., Araújo, N. M. S., Vasconcelos, I. M., Martins, T. F., de Morais, G. A., Gonçalves, J. F. D. C., Nagano, C. S., Carneiro, R. F., & Oliveira, J. T. A. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.04.174 · Cited by 15 · see citing works

Phytochemical profile and antimicrobial activity of Jatropha curcas extracts against oral microorganisms

Kamaruddin, A., Harun, W. H. F. W., Bakri, M., Abidin, S. A. Z., Giribabu, N., & Rahman, S. N. S. A. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e33422 · Cited by 9 · see citing works

Emerging Role of Sphingolipids in Amphotericin B Drug Resistance

Madaan, K., & Bari, V. K. (2023) · Microbial Drug Resistance · doi:10.1089/mdr.2022.0353 · Cited by 12 · see citing works

Genotyping and susceptibility testing uncovers large azole-resistant Candida tropicalis clade in Alexandria, Egypt

Spruijtenburg, B., Meijer, E. F. J., Xiao, M., Shawky, S. M., Meis, J. F. G. M., de Groot, T., & El‐Kholy, M. A. (2023) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2023.06.012 · Cited by 13 · see citing works

Molecular epidemiology and azole resistance mechanism study of Candida guilliermondii from a Chinese surveillance system

Cheng, J.-W., Liao, K., Kudinha, T., Yu, S.-Y., Xiao, M., Wang, H., Kong, F., & Xu, Y. (2017) · Scientific Reports · doi:10.1038/s41598-017-01106-7 · Cited by 13 · see citing works

The Risk Factors and Mechanisms of Azole Resistance of Candida tropicalis Blood Isolates in Thailand: A Retrospective Cohort Study

Leepattarakit, T., Tulyaprawat, O., & Ngamskulrungroj, P. (2022) · Journal of Fungi · doi:10.3390/jof8100983 · Cited by 8 · see citing works

Expanding the therapeutic options for Candida infections using novel inhibitors of secreted aspartyl proteases

Chakraborty, S., Rahate, K., Kumar, C., & Idicula‐Thomas, S. (2022) · Drug Development Research · doi:10.1002/ddr.22015 · Cited by 8 · see citing works

Lippia origanoides Essential Oil or Thymol in Combination with Fluconazole Produces Damage to Cells and Reverses the Azole-Resistant Phenotype of a Candida tropicalis Strain

Zapata-Zapata, C., Rojas, M., García, L. T., Quintero, W., Terrón, M. C., Luque, D., & Mesa-Arango, A. C. (2023) · Journal of Fungi · doi:10.3390/jof9090888 · Cited by 8 · see citing works

Alternative Oxidase – Aid or obstacle to combat the rise of fungal pathogens?

Edrich, E. S. M., Duvenage, L., & Gourlay, C. W. (2024) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2024.149031 · Cited by 7 · see citing works

Ketoconazole/calix[n]arenes-based compounds improve the antifungal activity against azole-resistant Candida isolates

Spadari, C. D. C., Barreto, T. L., de Queiroz, V. T., de Paiva, W. F., Fernandes, S. A., de Fátima, Â., & Ishida, K. (2022) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2022.101254 · Cited by 5 · see citing works

Azole Antifungal Drugs: Mode of Action and Resistance

Garcia‐Rubio, R., Monteiro, M. C., & Mellado, E. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809633-8.20731-0 · Cited by 8 · see citing works

Phenotypic Impact and Multivariable Assessment of Antifungal Susceptibility in Candida auris Survival Using a Galleria mellonella Model

Alvarruiz, J., Gaitán, A. C. R., Cabañero-Navalón, M. D., Pemán, J., Blanes-Hernández, R., Tejido, S. D. C., & García-Bustos, V. (2025) · Journal of Fungi · doi:10.3390/jof11060406 · Cited by 5 · see citing works

A MALDI-TOF MS-based multiple detection panel of drug resistance-associated multiple single-nucleotide polymorphisms in Candida tropicalis

Wan, F., Zhang, M., Guo, J., Lin, H., Zhou, X., Wang, L., & Wu, W. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.00764-24 · Cited by 5 · see citing works

Nephrotoxicity and fungal resistance associated with Amphotericin B

Berto, C., & Dalzochio, T. (2021) · Saúde e meio ambiente revista interdisciplinar · doi:10.24302/sma.v10.2720 · Cited by 6 · see citing works

Candida bloodstream infection: A clinical microbiology laboratory perspective

Pongrácz, J., & Kristóf, K. (2014) · Acta Microbiologica et Immunologica Hungarica · doi:10.1556/amicr.61.2014.3.11 · Cited by 4 · see citing works

Traditional Medicinal Plants of Higher Altitude of Himachal Pradesh as Functional Food Ingredient Cum Food Preservative and Bioavailability Enhancer of Anifungal AntibioticsPreprint

Rolta, R., Sharma, A., Kumar, V., Chauhan, P. K., Sourirajan, A., & Dev, K. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3299285 · Cited by 5 · see citing works

Candidemia chronicles: Retrospective analysis of candidemia epidemiology, species distribution, and antifungal susceptibility patterns in Bahrain

Saeed, N. K., Almusawi, S., & Al‐Beltagi, M. (2024) · World Journal of Virology · doi:10.5501/wjv.v13.i4.98839 · Cited by 4 · see citing works

Mycological Profile of Candida tropicalis and its Virulence Factors from Candidemia Patients at A Tertiary Care Facility

Mohanraj, H., Vinodhini, V. M., & Vajravelu, L. K. (2023) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.17.2.27 · Cited by 7 · see citing works

S5.1d Mechanisms of azole antifungal resistance in clinical isolates of Candida tropicalis

Ghosh, A. K., Paul, P., Shaw, D., Joshi, H., Singh, S., Chakrabarti, A., Rudramurthy, S. M., & Kaur, H. (2022) · Medical Mycology · doi:10.1093/mmy/myac072.s5.1d

Mechanisms of azole antifungal resistance in clinical isolates of Candida tropicalis

Paul, S., Shaw, D., Joshi, H. N., Singh, S., Chakrabarti, A., Rudramurthy, S. M., & Ghosh, A. K. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269721 · Cited by 47 · see citing works

Molecular mechanisms of azole resistance in Candida tropicalis isolates causing invasive candidiasis in China

Fan, X., Xiao, M., Zhang, D., Huang, J.-J., Wang, H., Hou, X., Zhang, L., Kong, F., Chen, S. C.-A., Tong, Z., et al. (2018) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2018.11.007 · Cited by 99 · see citing works

Mechanisms of azole resistance in 52 clinical isolates of Candida tropicalis in China

Jiang, C., Dong, D., Yu, B., Cai, G., Wang, X., Ji, Y., & Peng, Y. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks481 · Cited by 153 · see citing works

Azole Resistance and ERG11 Mutation in Clinical Isolates of Candida tropicalis

Siqueira, A. C., Bernardi, G., Arend, L. N. V. S., Cordeiro, G. T., Rosolen, D., Berti, F. C. B., Ferreira, A. M. M., Vasconcelos, T. M., Neves, B. C., Rodrigues, L. S., et al. (2025) · Journal of Fungi · doi:10.3390/jof11010024 · Cited by 22 · see citing works