Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B

Clinical and Laboratory Standards Institute

Gressner, A. M., & Arndt, T. (2019) · Springer Reference Medizin · doi:10.1007/978-3-662-48986-4_300416 · Cited by 5,092 · see citing works

Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem

Pfaller, M. A., & Diekema, D. J. (2007) · Clinical Microbiology Reviews · doi:10.1128/cmr.00029-06 · Cited by 4,174 · cited 1× · see citing works

The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

Russell, D. W. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161712 · Cited by 2,069 · see citing works

<i>Candida glabrata</i> : Review of Epidemiology, Pathogenesis, and Clinical Disease with Comparison to <i>C. albicans</i>

Fidel, P. L., Vazquez, J. A., & Sobel, J. D. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.1.80 · Cited by 953 · see citing works

Rare and Emerging Opportunistic Fungal Pathogens: Concern for Resistance beyondCandida albicansandAspergillus fumigatus

Pfaller, M. A., & Diekema, D. J. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.10.4419-4431.2004 · Cited by 695 · see citing works

Amphotericin B: spectrum and resistance

Ellis, D. (2002) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/49.suppl_1.7 · Cited by 474 · see citing works

Bloodstream Infections Due to <i>Candida</i> Species: SENTRY Antimicrobial Surveillance Program in North America and Latin America, 1997-1998

Pfaller, M. A., Jones, R. N., Doern, G. V., Sader, H. S., Messer, S. A., Houston, A., Coffman, S., Hollis, R. J., & The SENTRY Participant Group (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.3.747-751.2000 · Cited by 378 · see citing works

Mechanisms of Azole Resistance in Clinical Isolates of <i>Candida glabrata</i> Collected during a Hospital Survey of Antifungal Resistance

Sanguinetti, M., Posteraro, B., Fiori, B., Ranno, S., Torelli, R., & Fadda, G. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.2.668-679.2005 · Cited by 319 · see citing works

Mode of Action and Resistance to Azole Antifungals Associated with the Formation of 14α-Methylergosta-8,24(28)-dien-3β,6α-diol

Kelly, S. L., Lamb, D. C., Corran, A. J., Baldwin, B. C., & Kelly, D. E. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1272 · Cited by 296 · see citing works

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

Ferrari, S., Ischer, F., Calabrese, D., Posteraro, B., Sanguinetti, M., Fadda, G., Rohde, B., Bauser, C., Bader, O., & Sanglard, D. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000268 · Cited by 295 · see citing works

Structural Basis of Human CYP51 Inhibition by Antifungal Azoles

Strushkevich, N. V., Usanov, S. A., & Park, H. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.01.075 · Cited by 273 · see citing works

Role of ATP-Binding-Cassette Transporter Genes in High-Frequency Acquisition of Resistance to Azole Antifungals in <i>Candida glabrata</i>

Sanglard, D., Ischer, F., & Bille, J. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.4.1174-1183.2001 · Cited by 247 · see citing works

In Vitro Activities of Ravuconazole and Voriconazole Compared with Those of Four Approved Systemic Antifungal Agents against 6,970 Clinical Isolates of Candida spp

Pfaller, M. A., Messer, S. A., Hollis, R. J., Jones, R. N., & Diekema, D. J. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.6.1723-1727.2002 · Cited by 232 · see citing works

Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility

Geber, A., Hitchcock, C. A., Swartz, J. E., Pullen, F. S., Marsden, K. E., Kwon-Chung, K. J., & Bennett, J. E. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.12.2708 · Cited by 203 · see citing works

Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient

Krogh-Madsen, M., Arendrup, M. C., Heslet, L., & Knudsen, J. D. (2006) · Clinical Infectious Diseases · doi:10.1086/500939 · Cited by 201 · see citing works

Identification and Characterization of Four Azole-Resistant <i>erg3</i> Mutants of <i>Candida albicans</i>

Martel, C. M., Parker, J. E., Bader, O., Weig, M., Gross, U., Warrilow, A. G. S., Rolley, N., Kelly, D. E., & Kelly, S. L. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00348-10 · Cited by 168 · see citing works

A Clinical Isolate of <i>Candida albicans</i> with Mutations in <i>ERG11</i> (Encoding Sterol 14α-Demethylase) and <i>ERG5</i> (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B

Martel, C. M., Parker, J. E., Bader, O., Weig, M., Gross, U., Warrilow, A. G. S., Kelly, D. E., & Kelly, S. L. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00303-10 · Cited by 165 · see citing works

Rhodamine 6G efflux for the detection of CDR1-overexpressing azole-resistant Candidaalbicans strains

Maesaki, S., Marichal, P., Bossche, H. V., Sanglard, D., & Kohno, S. (1999) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/44.1.27 · Cited by 162 · see citing works

Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency

Krakowiak, P. A. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg172 · Cited by 161 · see citing works

From Saccharomyces cerevisiae to Candida glabrata in a few easy steps: important adaptations for an opportunistic pathogen: Candida glabrata stress response

Roetzer, A., Gabaldón, T., & Schüller, C. (2011) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2010.02102.x · Cited by 154 · see citing works

Mechanisms of Azole Resistance in Petite Mutants of <i>Candida glabrata</i>

Brun, S., Bergès, T., Poupard, P., Vauzelle-Moreau, C., Renier, G., Chabasse, D., & Bouchara, J.-P. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.5.1788-1796.2004 · Cited by 151 · see citing works

Antibiotic resistance surveillance: action for international studies

Morris, A. K. (2002) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/49.1.7 · Cited by 136 · see citing works

Azole Drugs Are Imported By Facilitated Diffusion in Candida albicans and Other Pathogenic Fungi

Mansfield, B. E., Oltean, H. N., Oliver, B. G., Hoot, S. J., Leyde, S. E., Hedstrom, L., & White, T. C. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001126 · Cited by 111 · see citing works

Reduced Susceptibility to Polyenes Associated with a Missense Mutation in the <i>ERG6</i> Gene in a Clinical Isolate of <i>Candida glabrata</i> with Pseudohyphal Growth

Vandeputte, P., Tronchin, G., Bergès, T., Hennequin, C., Chabasse, D., & Bouchara, J.-P. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01510-06 · Cited by 109 · see citing works

Acquisition of Flucytosine, Azole, and Caspofungin Resistance in Candida glabrata Bloodstream Isolates Serially Obtained from a Hematopoietic Stem Cell Transplant Recipient

Chapeland‐Leclerc, F., Hennequin, C., Papon, N., Noël, T., Girard, A., Socié, G., Ribaud, P., & Lacroix, C. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01138-09 · Cited by 104 · see citing works

The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum

Nakayama, H., Tanabe, K., Bard, M., Hodgson, W., Wu, S., Takemori, D., Aoyama, T., Kumaraswami, N. S., Metzler, L., Takano, Y., et al. (2007) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkm321 · Cited by 78 · see citing works

Inactivation of Transcription Factor Gene <i>ACE2</i> in the Fungal Pathogen <i>Candida glabrata</i> Results in Hypervirulence

Kamran, M., Calcagno, A.-M., Findon, H., Bignell, E., Jones, M. D., Warn, P., Hopkins, P., Denning, D. W., Butler, G., Rogers, T., et al. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.2.546-552.2004 · Cited by 75 · see citing works

Phenotypic Switching and Mating Type Switching of <i>Candida glabrata</i> at Sites ofColonization

Brockert, P. J., Lachke, S. A., Srikantha, T., Pujol, C., Galask, R., & Soll, D. R. (2003) · Infection and Immunity · doi:10.1128/iai.71.12.7109-7118.2003 · Cited by 75 · see citing works

A single amino acid substitution converts cytochrome P45014DM to an inactive form, cytochrome P450SG1: Complete primary structures deduced from cloned DNAs

Ishida, N., Aoyama, Y., Hatanaka, R., Oyama, Y., Imajo, S., Ishiguro, M., Oshima, T., Nakazato, H., Noguchi, T., Maitra, U. S., et al. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)81087-8 · Cited by 65 · see citing works

A yeast sterol auxotroph ( erg 25) is rescued by addition of azole antifungals and reduced levels of heme

Gachotte, D. J., Pierson, C. A., Lees, N. D., Barbuch, R. J., Koegel, C., & Bard, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11173 · Cited by 58 · see citing works

Sterol uptake in Candida glabrata: Rescue of sterol auxotrophic strains

Bard, M., Sturm, A. M., Pierson, C. A., Brown, S., Rogers, K. M., Nabinger, S., Eckstein, J., Barbuch, R., Lees, N. D., Howell, S. A., et al. (2005) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2005.03.001 · Cited by 58 · see citing works

Candida glabrata erg1 Mutant with Increased Sensitivity to Azoles and to Low Oxygen Tension

Tsai, H., Bard, M., Izumikawa, K., Krol, A. A., Sturm, A. M., Culbertson, N. T., Pierson, C. A., & Bennett, J. E. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.7.2483-2489.2004 · Cited by 56 · see citing works

Cholesterol Import by Aspergillus fumigatus and Its Influence on Antifungal Potency of Sterol Biosynthesis Inhibitors

Xiong, Q., Hassan, S. A., Wilson, W. K., Han, X. Y., May, G. S., Tarrand, J. J., & Matsuda, S. P. T. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.2.518-524.2005 · Cited by 55 · see citing works

High-throughput phenotypic profiling of gene–environment interactions by quantitative growth curve analysis in Saccharomyces cerevisiae

Weiss, A., Delproposto, J., & Giroux, C. N. (2004) · Analytical Biochemistry · doi:10.1016/j.ab.2003.12.020 · Cited by 50 · see citing works

Sterol biosynthesis and sterol uptake in the fungal pathogen Pneumocystis carinii

Joffrion, T. M., & Cushion, M. T. (2010) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2010.02007.x · Cited by 48 · see citing works

Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14α-Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B

Martel, C. M., Parker, J. E., Warrilow, A. G. S., Rolley, N. J., Kelly, S. L., & Kelly, D. E. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00349-10 · Cited by 45 · see citing works

In Vitro and In Vivo Effects of 14α-Demethylase ( ERG11 ) Depletion in Candida glabrata

Nakayama, H., Nakayama, N., Arisawa, M., & Aoki, Y. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.11.3037-3045.2001 · Cited by 39 · see citing works

Purification, Reconstitution, and Inhibition of Cytochrome P-450 Sterol Δ 22 -Desaturase from the Pathogenic Fungus Candida glabrata

Lamb, D. C., Maspahy, S., Kelly, D. E., Manning, N. J., Geber, A., Bennett, J. E., & Kelly, S. L. (1999) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.43.7.1725 · Cited by 35 · see citing works

Isolation of cholesterol-dependent Candida glabrata from clinical specimens

Hazen, K. C., Stei, J., Darracott, C., Breathnach, A. S., May, J., & Howell, S. A. (2005) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2004.12.006 · Cited by 32 · see citing works

Hypersusceptibility to Azole Antifungals in a Clinical Isolate of <i>Candida glabrata</i> with Reduced Aerobic Growth

Vandeputte, P., Tronchin, G., Rocher, F., Renier, G., Bergès, T., Chabasse, D., & Bouchara, J.-P. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01384-08 · Cited by 26 · see citing works

Requirement of heme to replace the sparking sterol function in the yeast Saccharomyces cerevisiae

Smith, S. J., & Parks, L. W. (1997) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/s0005-2760(96)00165-8 · Cited by 20 · see citing works

Metabolic Control Analysis and Engineering of the Yeast Sterol Biosynthetic Pathway

Groeneveld, P., Rolley, N. J., Kell, D. B., Kelly, S. L., & Kelly, D. E. (2002) · Molecular Biology Reports · doi:10.1023/a:1020342032302 · Cited by 11 · see citing works

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species

Whaley, S. G., Berkow, E. L., Rybak, J. M., Nishimoto, A. T., Barker, K. S., & Rogers, P. D. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.02173 · Cited by 900 · see citing works

Antifungal Drug Resistance: Molecular Mechanisms in <i>Candida albicans</i> and Beyond

Lee, Y., Puumala, E., Robbins, N., & Cowen, L. E. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00199 · Cited by 801 · see citing works

Fluconazole resistance in &lt;em&gt;Candida&lt;/em&gt; species: a current perspective

Berkow, E., & Lockhart, S. (2017) · Infection and Drug Resistance · doi:10.2147/idr.s118892 · Cited by 542 · see citing works

Candidiasis and Mechanisms of Antifungal Resistance

Bhattacharya, S., Sae-Tia, S., & Fries, B. C. (2020) · Antibiotics · doi:10.3390/antibiotics9060312 · Cited by 474 · see citing works

Echinocandins – structure, mechanism of action and use in antifungal therapy

Szymański, M., Chmielewska, S., Czyżewska, U., Malinowska, M., & Tylicki, A. (2022) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2022.2050224 · Cited by 281 · see citing works

Role of FKS mutations in Candida glabrata: MIC values, echinocandin resistance, and multidrug resistance

Pham, C. D., Iqbal, N., Bolden, C. B., Kuykendall, R. J., Harrison, L. H., Farley, M. M., Schaffner, W., Beldavs, Z. G., Chiller, T. M., Park, B. J., et al. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03255-14 · Cited by 231 · see citing works

Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance

Carolus, H., Pierson, S., Muñoz, J. F., Subotić, A., Cruz, R. B., Cuomo, C. A., & Van Dijck, P. (2021) · mBio · doi:10.1128/mbio.03333-20 · Cited by 211 · see citing works

Candida auris Pan-Drug-Resistant to Four Classes of Antifungal Agents

Jacobs, S. E., Jacobs, J. L., Dennis, E. K., Taimur, S., Rana, M., Patel, D., Gitman, M., Patel, G., Schaefer, S., Iyer, K., et al. (2022) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00053-22 · Cited by 190 · see citing works

Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

Gonçalves, S. S., Souza, A. C. R., Chowdhary, A., Meis, J. F. G. M., & Colombo, A. L. (2016) · Mycoses · doi:10.1111/myc.12469 · Cited by 182 · see citing works

Emerging multidrug-resistant Candida species

Colombo, A. L., Júnior, J. N. D. A., & Guinea, J. (2017) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000411 · Cited by 177 · see citing works

The Clinical Candidate VT-1161 Is a Highly Potent Inhibitor of Candida albicans CYP51 but Fails To Bind the Human Enzyme

Warrilow, A. G. S., Hull, C. M., Parker, J. E., Garvey, E. P., Hoekstra, W. J., Moore, W. R., Schotzinger, R. J., Kelly, D. E., & Kelly, S. L. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03707-14 · Cited by 173 · see citing works

The Quiet and Underappreciated Rise of Drug-Resistant Invasive Fungal Pathogens

Arastehfar, A., Lass-Flörl, C., Garcia-Rubio, R., Daneshnia, F., Ilkit, M., Boekhout, T., Gabaldon, T., & Perlin, D. S. (2020) · Journal of Fungi · doi:10.3390/jof6030138 · Cited by 145 · see citing works

Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications

Forastiero, A., Mesa-Arango, A. C., Alastruey-Izquierdo, A., Alcazar-Fuoli, L., Bernal-Martinez, L., Pelaez, T., Lopez, J. F., Grimalt, J. O., Gomez-Lopez, A., Cuesta, I., et al. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00477-13 · Cited by 131 · see citing works

Candida glabrata Biofilms: How Far Have We Come?

Rodrigues, C., Rodrigues, M., Silva, S., & Henriques, M. (2017) · Journal of Fungi · doi:10.3390/jof3010011 · Cited by 129 · see citing works

Molecular Mechanisms of Drug Resistance in Clinical Candida Species Isolated from Tunisian Hospitals

Eddouzi, J., Parker, J. E., Vale-Silva, L. A., Coste, A., Ischer, F., Kelly, S., Manai, M., & Sanglard, D. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00555-13 · Cited by 128 · see citing works

Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms and <i>In Vivo</i> Impact in Infected Galleria mellonella Larvae

Souza, A. C. R., Fuchs, B. B., Pinhati, H. M. S., Siqueira, R. A., Hagen, F., Meis, J. F., Mylonakis, E., & Colombo, A. L. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01177-15 · Cited by 121 · see citing works

Molecular basis of antifungal drug resistance in yeasts

Morio, F., Jensen, R. H., Le Pape, P., & Arendrup, M. C. (2017) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2017.05.012 · Cited by 114 · see citing works

Antifungal drug resistance mechanisms in pathogenic fungi: from bench to bedside

Cuenca‐Estrella, M. (2013) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12495 · Cited by 97 · see citing works

Genetic Drivers of Multidrug Resistance in Candida glabrata

Healey, K. R., Jimenez Ortigosa, C., Shor, E., & Perlin, D. S. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01995 · Cited by 93 · see citing works

Two Clinical Isolates of Candida glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in <i>ERG2</i>

Hull, C. M., Bader, O., Parker, J. E., Weig, M., Gross, U., Warrilow, A. G. S., Kelly, D. E., & Kelly, S. L. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01145-12 · Cited by 90 · see citing works

Drug resistance mechanisms and their regulation in non- albicans Candida species

Kołaczkowska, A., & Kołaczkowski, M. (2016) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv445 · Cited by 88 · see citing works

Azole Resistance in Candida glabrata

Whaley, S. G., & Rogers, P. D. (2016) · Current Infectious Disease Reports · doi:10.1007/s11908-016-0554-5 · Cited by 85 · see citing works

Analysis of sphingolipids, sterols, and phospholipids in human pathogenic Cryptococcus strains

Singh, A., MacKenzie, A., Girnun, G. D., & Poeta, M. D. (2017) · Journal of Lipid Research · doi:10.1194/jlr.m078600 · Cited by 85 · see citing works

ERG6 and ERG2 Are Major Targets Conferring Reduced Susceptibility to Amphotericin B in Clinical Candida glabrata Isolates in Kuwait

Ahmad, S., Joseph, L., Parker, J. E., Asadzadeh, M., Kelly, S. L., Meis, J. F. G. M., & Khan, Z. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01900-18 · Cited by 83 · see citing works

Opportunistic invasive fungal disease in patients with type 2 diabetes mellitus from Southern China: Clinical features and associated factors

Lao, M., Li, C., Li, J., Chen, D., Ding, M., & Gong, Y. (2019) · Journal of Diabetes Investigation · doi:10.1111/jdi.13183 · Cited by 81 · see citing works

Candida glabrata Antifungal Resistance and Virulence Factors, a Perfect Pathogenic Combination

León, M. G. F.-D., Hernández‐Castro, R., Conde-Cuevas, E., García-Coronel, I. H., Vázquez-Aceituno, V. A., Soriano-Ursua, M. A., Farfán‐García, E. D., Ocharan-Hernández, M. E., Rodríguez‐Cerdeira, C., Arenas, R., et al. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13101529 · Cited by 78 · see citing works

Tipping the balance both ways: drug resistance and virulence in Candida glabrata

Vale-Silva, L. A., & Sanglard, D. (2015) · FEMS Yeast Research · doi:10.1093/femsyr/fov025 · Cited by 68 · see citing works

Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Mwenechanya, R., Kovářová, J., Dickens, N. J., Mudaliar, M., Herzyk, P., Vincent, I. M., Weidt, S. K., Burgess, K. E., Burchmore, R., Pountain, A. W., et al. (2017) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0005649 · Cited by 61 · see citing works

An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains

Salazar, S. B., Simões, R., Pedro, N. A., Pinheiro, M. J. F., Carvalho, M. F. N. N., & Mira, N. P. (2020) · Journal of Fungi · doi:10.3390/jof6010023 · Cited by 55 · see citing works

Low Level of Antifungal Resistance in Iranian Isolates of Candida glabrata Recovered from Blood Samples in a Multicenter Study from 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of PDR1

Arastehfar, A. A., Daneshnia, F., Zomorodian, K., Najafzadeh, M. J., Khodavaisy, S., Zarrinfar, H., Hagen, F., Shahrabadi, Z. Z., Lackner, M., Mirhendi, H., et al. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02503-18 · Cited by 54 · see citing works

<i>UPC2A</i> Is Required for High-Level Azole Antifungal Resistance in Candida glabrata

Whaley, S. G., Caudle, K. E., Vermitsky, J.-P., Chadwick, S. G., Toner, G., Barker, K. S., Gygax, S. E., & Rogers, P. D. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02217-13 · Cited by 52 · see citing works

Fluconazole-Resistant Candida glabrata Bloodstream Isolates, South Korea, 2008–2018

Won, E. J., Choi, M. J., Kim, M., Yong, D., Lee, W. G., Uh, Y., Kim, T. S., Byeon, S. A., Lee, S. Y., Kim, S. H., et al. (2021) · Emerging infectious diseases · doi:10.3201/eid2703.203482 · Cited by 52 · see citing works

Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost

Bédard, C., Gagnon‐Arsenault, I., Boisvert, J., Plante, S., Dubé, A. K., Pageau, A., Fijarczyk, A., Sharma, J., Maroc, L., Shapiro, R. S., et al. (2024) · Nature Microbiology · doi:10.1038/s41564-024-01819-2 · Cited by 50 · see citing works

Antifungal drug susceptibility, molecular basis of resistance to echinocandins and molecular epidemiology of fluconazole resistance among clinical Candida glabrata isolates in Kuwait

Al-Baqsami, Z. F., Ahmad, S., & Khan, Z. (2020) · Scientific Reports · doi:10.1038/s41598-020-63240-z · Cited by 50 · see citing works

Unmasking the Amphotericin B Resistance Mechanisms in Candida haemulonii Species Complex

Silva, L. N., Oliveira, S. S. C., Magalhães, L. B., Andrade-Neto, V. V., Torres-Santos, E. C., de Carvalho, M. D. C., Pereira, M. D., Branquinha, M. H., & dos Santos, A. L. S. (2020) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.0c00117 · Cited by 49 · see citing works

Liposomal and Deoxycholate Amphotericin B Formulations: Effectiveness against Biofilm Infections of Candida spp.

Rodrigues, C. F., & Henriques, M. (2017) · Pathogens · doi:10.3390/pathogens6040062 · Cited by 47 · see citing works

A Transcriptomics Approach To Unveiling the Mechanisms of <i>In Vitro</i> Evolution towards Fluconazole Resistance of a <i>Candida glabrata</i> Clinical Isolate

Cavalheiro, M., Costa, C., Silva-Dias, A., Miranda, I. M., Wang, C., Pais, P., Pinto, S. N., Mil-Homens, D., Sato-Okamoto, M., Takahashi-Nakaguchi, A., et al. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00995-18 · Cited by 42 · see citing works

Genetic Basis of Azole and Echinocandin Resistance in Clinical Candida glabrata in Japan

Khalifa, H. O., Arai, T., Majima, H., Watanabe, A., & Kamei, K. (2020) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00783-20 · Cited by 42 · see citing works

Mechanisms of azole resistance among clinical isolates of Candida glabrata in Poland

Szweda, P., Gucwa, K., Romanowska, E., Dzierżanowska‐Fangrat, K., Naumiuk, Ł., Brillowska‐Dąbrowska, A., Wojciechowska‐Koszko, I., & Milewski, S. (2015) · Journal of Medical Microbiology · doi:10.1099/jmm.0.000062 · Cited by 42 · see citing works

Calcium signaling mediates antifungal activity of triazole drugs in the Aspergilli

Liu, F., Pu, L., Zheng, Q.-Q., Zhang, Y., Gao, R., Xu, X.-S., Zhang, S., & Lü, L. (2014) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2014.12.005 · Cited by 41 · see citing works

Sphingolipids: Regulators of azole drug resistance and fungal pathogenicity

Song, J., Xiao, L., & Li, R. (2020) · Molecular Microbiology · doi:10.1111/mmi.14586 · Cited by 38 · see citing works

The effect of hypoxia on the lipidome of recombinant Pichia pastoris

Adelantado, N., Tarazona, P., Grillitsch, K., Garcia‐Ortega, X., Monforte, S., Valero, F., Feußner, I., Daum, G., & Ferrer, P. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0699-4 · Cited by 37 · see citing works

Analysis of mutations in West Australian populations of Blumeria graminis f. sp. hordei CYP51 conferring resistance to DMI fungicides

Tucker, M. A., López-Ruiz, F. J., Cools, H. J., Mullins, J. G. L., Jayasena, K. W., & Oliver, R. P. (2019) · Pest Management Science · doi:10.1002/ps.5636 · Cited by 36 · see citing works

Azole-Resistant Alleles of ERG11 in Candida glabrata Trigger Activation of the Pdr1 and Upc2A Transcription Factors

Vu, B. G., & Moye-Rowley, S. (2022) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02098-21 · Cited by 28 · see citing works

Raman Metabolomics of Candida auris Clades: Profiling and Barcode Identification

Pezzotti, G., Kobara, M., Nakaya, T., Imamura, H., Fujii, T., Miyamoto, N., Adachi, T., Yamamoto, T., Kanamura, N., Ohgitani, E., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911736 · Cited by 28 · see citing works

The heme-binding protein Dap1 links iron homeostasis to azole resistance via the P450 protein Erg11 inCandida glabrata

Hosogaya, N., Miyazaki, T., Nagi, M., Tanabe, K., Minematsu, A., Nagayoshi, Y., Yamauchi, S., Nakamura, S., Imamura, Y., Izumikawa, K., et al. (2013) · FEMS Yeast Research · doi:10.1111/1567-1364.12043 · Cited by 28 · see citing works

Collateral sensitivity counteracts the evolution of antifungal drug resistance in Candida auris

Carolus, H., Sofras, D., Boccarella, G., Jacobs, S., Biriukov, V. V., Goossens, L., Chen, A., Vantyghem, I., Verbeeck, T., Pierson, S., et al. (2024) · Nature Microbiology · doi:10.1038/s41564-024-01811-w · Cited by 27 · see citing works

Expression Patterns of ABC Transporter Genes in Fluconazole-Resistant Candida glabrata

Gohar, A. A., Badali, H., Shokohi, T., Nabili, M., Amirrajab, N., & Moazeni, M. (2017) · Mycopathologia · doi:10.1007/s11046-016-0074-8 · Cited by 25 · see citing works

Insights into the Multi-Azole Resistance Profile in Candida haemulonii Species Complex

Silva, L. N., Ramos, L. S., de Oliveira, S. S. C., Magalhães, L. B., Squizani, E. D., Kmetzsch, L., Vainstein, M. H., Branquinha, M. H., & dos Santos, A. L. S. (2020) · Journal of Fungi · doi:10.3390/jof6040215 · Cited by 25 · see citing works

Candida parapsilosis Sensu Stricto Antifungal Resistance Mechanisms and Associated Epidemiology

Franconi, I., Rizzato, C., Poma, N. V., Tavanti, A., & Lupetti, A. (2023) · Journal of Fungi · doi:10.3390/jof9080798 · Cited by 25 · see citing works

Does the use of antifungal agents in agriculture and food foster polyene resistance development? A reason for concern

Dalhoff, A. (2017) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2017.10.024 · Cited by 23 · see citing works

In vitro activities of amphotericin B deoxycholate and liposomal amphotericin B against 604 clinical yeast isolates

Montagna, M. T., Lovero, G., Coretti, C., Giglio, O. D., Martinelli, D., Bedini, A., Delia, M., Rosato, A., Codeluppi, M., & Caggiano, G. (2014) · Journal of Medical Microbiology · doi:10.1099/jmm.0.075507-0 · Cited by 21 · see citing works

Alternative ergosterol biosynthetic pathways confer antifungal drug resistance in the human pathogens within the Mucor species complex

Navarro-Mendoza, M. I., Arques, C. P., Parker, J. E., Xu, Z., Kelly, S. L., & Heitman, J. (2024) · mBio · doi:10.1128/mbio.01661-24 · Cited by 20 · see citing works

Cyclodextrin-mediated self-associating chitosan micro-platelets act as a drug booster against Candida glabrata mucosal infection in immunocompetent mice

Grisin, T., Bories, C., Loiseau, P. M., & Bouchemal, K. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.01.048 · Cited by 20 · see citing works

Hotspot gene conversion between FKS1 and FKS2 in echinocandin resistant Candida glabrata serial isolates

Zajac, C., Scott, N. E., Kline, S., Erayil, S. E., & Selmecki, A. M. (2025) · npj Antimicrobials and Resistance · doi:10.1038/s44259-025-00102-6 · Cited by 19 · see citing works

Amino acid substitutions in Erg11p of azole-resistant Candida glabrata: Possible effective substitutions and homology modelling

Nabili, M., Gohar, A. A., Badali, H., Mohammadi, R., & Moazeni, M. (2016) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2016.03.003 · Cited by 18 · see citing works

A Review on Molecular Mechanisms of Antifungal Resistance in Candida glabrata : Update and Recent Advances

Lotfali, E., Fattahi, A., Sayyahfar, S., Ghasemi, R., Rabiei, M. M., Fathi, M., Vakili, K. G., Deravi, N., Soheili, A., Toreyhi, H., et al. (2021) · Microbial Drug Resistance · doi:10.1089/mdr.2020.0235 · Cited by 17 · see citing works

Isolation of cholesterol-dependent, multidrug-resistant Candida glabratastrains from blood cultures of a candidemia patient in Kuwait

Khan, Z., Ahmad, S., Joseph, L., & Alobaid, K. (2014) · BMC Infectious Diseases · doi:10.1186/1471-2334-14-188 · Cited by 16 · see citing works

Two Sequential Clinical Isolates of Candida glabrata with Multidrug-Resistance to Posaconazole and Echinocandins

Wang, Q., Li, Y., Cai, X., Li, R., Zheng, B., Yang, E., Liang, T., Yang, X., Wan, Z., & Liu, W. (2021) · Antibiotics · doi:10.3390/antibiotics10101217 · Cited by 15 · see citing works

Multiple routes to fungicide resistance: Interaction of Cyp51 gene sequences, copy number and expression

Arnold, C. J., Hahn, E. A., Whetten, R. B., Chartrain, L., Cheema, J., Brown, J. K. M., & Cowger, C. (2024) · Molecular Plant Pathology · doi:10.1111/mpp.13498 · Cited by 15 · see citing works

Disclosing azole resistance mechanisms in resistant Candida glabrata strains encoding wild-type or gain-of-function CgPDR1 alleles through comparative genomics and transcriptomics

Salazar, S. B., Pinheiro, M. J. F., Sotti-Novais, D., Soares, A. R., Lopes, M. M., Ferreira, T., Rodrigues, V., Fernandes, F., & Mira, N. P. (2022) · G3 Genes Genomes Genetics · doi:10.1093/g3journal/jkac110 · Cited by 15 · see citing works

Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in ERG2 as a Major Mechanism Conferring Reduced Susceptibility to Amphotericin B in Candida kefyr

Asadzadeh, M., Alfouzan, W. A., Parker, J. E., Meis, J. F. G. M., Kelly, S. L., Joseph, L., & Ahmad, S. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.01474-23 · Cited by 15 · see citing works

Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of Candida glabrata (CgHMGR), Thus Decreasing Yeast Viability and Ergosterol Synthesis

Madrigal-Aguilar, D. A., González-Silva, A., Rosales-Acosta, B., Bautista-Crescencio, C., Ortiz-Álvarez, J., Escalante, C. H., Sánchez-Navarrete, J., Hernández-Rodríguez, C., Chamorro, G., Tamariz, J., et al. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.01642-21 · Cited by 14 · see citing works

The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors

Chiu, J. E., Thekkiniath, J., Mehta, S. S., Müller, C., Bracher, F., & Mamoun, C. B. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.009791 · Cited by 14 · see citing works

Inositol Phosphoryl Transferase, Ipt1, Is a Critical Determinant of Azole Resistance and Virulence Phenotypes in Candida glabrata

Shahi, G., Kumar, M., Khandelwal, N., Banerjee, A., Sarkar, P., Kumari, S., Esquivel, B. D., Chauhan, N., Chattopadhyay, A., White, T. C., et al. (2022) · Journal of Fungi · doi:10.3390/jof8070651 · Cited by 11 · see citing works

Genomewide Elucidation of Drug Resistance Mechanisms for Systemically Used Antifungal Drugs Amphotericin B, Caspofungin, and Voriconazole in the Budding Yeast

Bozlak, Ç. E. B., Ercan, İ., Işık, E., Şahin, E., Balcioglu, O., Kodedová, M., Zimmermannová, O., Dündar, M., Sychrová, H., & Koç, A. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02268-18 · Cited by 11 · see citing works

A critical role of farnesol in the modulation of Amphotericin B and Aureobasidin A antifungal drug susceptibility

Mahendrarajan, V., & Bari, V. K. (2022) · Mycology&#58 An International Journal on Fungal Biology · doi:10.1080/21501203.2022.2138599 · Cited by 11 · see citing works

Impact of ERG6 Gene Deletion on Membrane Composition and Properties in the Pathogenic Yeast Candida glabrata

Jacko, J., Morvová, M., Hervay, N. T., Eliaš, D., Gbelská, Y., Waczulı́ková, I., Gášková, D., Balážová, M., & Šikurová, L. (2024) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-024-01599-w · Cited by 10 · see citing works

Emergence of invasive candidiasis with multiple Candida species exhibiting azole and echinocandin resistance

Huang, S., Song, Y., Lv, G., Liu, J., Zhao, J., Wang, L.-L., & Xiang, M.-J. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1550894 · Cited by 10 · see citing works

Mitigation of Human-Pathogenic Fungi that Exhibit Resistance to Medical Agents: Can Clinical Antifungal Stewardship Help?

Hull, C. M., Purdy, N. J., & Moody, S. C. (2014) · Future Microbiology · doi:10.2217/fmb.13.160 · Cited by 10 · see citing works

Species-Specific Differences in C-5 Sterol Desaturase Function Influence the Outcome of Azole Antifungal Exposure

Luna-Tapia, A., Parker, J. E., Kelly, S. L., & Palmer, G. E. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01044-21 · Cited by 10 · see citing works

Limosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion

Zangl, I., Beyer, R., Gattesco, A., Labuda, R., Pap, I.-J., Strauss, J., & Schüller, C. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.03326-22 · Cited by 10 · see citing works

Expression of ERG11 and efflux pump genes CDR1, CDR2 and SNQ2 in voriconazole susceptible and resistant Candida glabrata strains

Navarro-Rodríguez, P., Martín‐Vicente, A., López‐Fernández, L., Guarro, J., & Capilla, J. (2019) · Medical Mycology · doi:10.1093/mmy/myz014 · Cited by 9 · see citing works

What ‘Omics can tell us about antifungal adaptation

Ribeiro, G. F., Denes, E., Heaney, H., & Childers, D. S. (2021) · FEMS Yeast Research · doi:10.1093/femsyr/foab070 · Cited by 9 · see citing works

Genetic microevolution of clinical Candida auris with reduced Amphotericin B sensitivity in China

Tian, S., Chen, R., Li, H., Wu, Y., Wu, N., Yunzhuo, C., Jiang, N., Zhang, J., & Shang, H. (2024) · Emerging Microbes & Infections · doi:10.1080/22221751.2024.2398596 · Cited by 9 · see citing works

A CTG Clade Candida Yeast Genetically Engineered for the Genotype-Phenotype Characterization of Azole Antifungal Resistance in Human-Pathogenic Yeasts

Accoceberry, I., Rougeron, A., Biteau, N., Chevrel, P., Fitton‐Ouhabi, V., & Noël, T. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01483-17 · Cited by 9 · see citing works

New pharmacotherapeutic strategies for drug-resistant Candida infections: a review

Raposa, J., & Vázquez, J. A. (2024) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2024.2433605 · Cited by 8 · see citing works

For Debate: May the Use of the Polyene Macrolide Natamycin as a Food Additive Foster Emergence of Polyene-Resistance in Candida Species?

Dalhoff, A. (2017) · Clinical Microbiology Open Access · doi:10.4172/2327-5073.1000287 · Cited by 8 · see citing works

Unmasking of CgYor1-Dependent Azole Resistance Mediated by Target of Rapamycin (TOR) and Calcineurin Signaling in Candida glabrata

Kumari, S., Kumar, M., Esquivel, B. D., Wasi, M., Pandey, A. K., Khandelwal, N., Mondal, A. K., White, T. C., Prasad, R., & Gaur, N. A. (2022) · mBio · doi:10.1128/mbio.03545-21 · Cited by 8 · see citing works

Analysis of molecular resistance to azole and echinocandin in Candida species in patients with vulvovaginal candidiasis

Lotfali, E., Erami, M., Fattahi, A., Nemati, H., Ghasemi, Z., & Mahdavi, E. (2022) · Current Medical Mycology · doi:10.18502/cmm.8.2.10326 · Cited by 8 · see citing works

Mechanisms of Resistance to Antifungal Agents

Perlin, D. S. (2015) · ASM Press eBooks · doi:10.1128/9781555817381.ch130 · Cited by 7 · see citing works

Post-transcriptional control of antifungal resistance in human fungal pathogens

Sharma, C., & Kadosh, D. (2023) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2022.2080527 · Cited by 6 · see citing works

Activity of Rezafungin Against Echinocandin Non–wild type Candida glabrata Clinical Isolates From a Global Surveillance Program

Castanheira, M., Deshpande, L. M., Kimbrough, J. H., & Winkler, M. (2025) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofae702 · Cited by 6 · see citing works

Fluconazole-induced changes in azole resistance and biofilm production in Candida glabrata in vitro

Xia, C., Liu, R., Zhang, S., Shen, J., & Wang, Z. (2025) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2025.116683 · Cited by 6 · see citing works

Review of the Current Management of Urinary Tract Infections due to Fluconazole-Resistant and Non-Albicans Candida Species

Tan, X., Baugh, K., Bulman, Z. P., & Wenzler, E. (2020) · Current Fungal Infection Reports · doi:10.1007/s12281-020-00388-1 · Cited by 6 · see citing works

How Yeast Antifungal Resistance Gene Analysis Is Essential to Validate Antifungal Susceptibility Testing Systems

Pellaton, N., Sanglard, D., Lamoth, F., & Coste, A. T. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.859439 · Cited by 6 · see citing works

Investigation of the Defective Growth Pattern and Multidrug Resistance in a Clinical Isolate of Candida glabrata Using Whole-Genome Sequencing and Computational Biology Applications

Merdan, O., Şişman, A. S., Aksoy, S. A., Kızıl, S., Tüzemen, N. Ü., Yılmaz, E., & Ener, B. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.00776-22 · Cited by 6 · see citing works

Azoles Used in Agriculture as Possible Cause of Azole-Resistance in Clinical Candida Isolates

Kaur, H., Yadav, A., Wadhwa, K., Jain, K., & Ghorai, S. M. (2021) · Biosciences Biotechnology Research Asia · doi:10.13005/bbra/2884 · Cited by 4 · see citing works

Multidrug- and Cross-Resistant Candida: the Looming Threat

Lackner, M., Martín‐Vicente, A., & Lass‐Flörl, C. (2014) · Current Fungal Infection Reports · doi:10.1007/s12281-014-0210-1 · Cited by 4 · see citing works

Burden of Fungal Coinfections with HIV in Sub-Saharan Africa: Prevalence and Implications

Odoom, A., & Ofosu, W. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.115137 · Cited by 3 · see citing works

Design, synthesis and biological evaluation of natural product echinocandin derivatives

Chu, S., Zheng, Y., Wang, G., Su, S., Wang, H., Chen, S., & Wu, X. (2025) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2025.117896 · Cited by 3 · see citing works

Pathogenic Features, Experimental Models, and Molecular Tools of Human Fungal Pathogens: Who’s on WHO’s Radar?

Narayanan, A., Shaji, A. A., Pullepu, D., Bhattacharya, J., & Sanyal, K. (2025) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.5c00081 · Cited by 3 · see citing works

Phylogenomic analysis and genetic mechanisms of antifungal resistance in clinical isolates of Candida glabrata ( Nakaseomyces glabratus ) from across Canada, 2013–2020

Luca, D. G. D., Alexander, D. C., Dingle, T. C., Dufresne, P. J., Fuller, J., German, G. J., Haldane, D. J. M., Hoang, L., Jiao, L., Kus, J. V., et al. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.01803-25 · Cited by 3 · see citing works

Osh2 mediates Candida species resistance to miltefosine by regulating zymosterol accumulation

Wu, Y., Dai, Y., Lu, H., Jiang, X., & Wang, Y. (2025) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00427-25 · Cited by 2 · see citing works

Nonantifungal Clinical Drug Interventions and Human-Commensal Fungi: What are we Selecting?

Hull, C. M., & Purdy, N. J. (2013) · Future Microbiology · doi:10.2217/fmb.13.45 · Cited by 2 · see citing works

Mechanisms of Resistance to Antifungal Agents

Perlin, D. S. (2023) · ClinMicroNow · doi:10.1002/9781683670438.mcm0134 · Cited by 2 · see citing works

Non-ergosterol lipid remodeling governs amphotericin B susceptibility via TOR–calcineurin signaling in Candida glabrata

Kumar, M., Kumari, S., Wasi, M., Ali, B., Kumar, P., Sharma, G. L., Singh, A., Dantas, A. D. S., Gow, N. A. R., Gaur, N. A., et al. (2026) · The Cell Surface · doi:10.1016/j.tcsw.2026.100180 · Cited by 1 · see citing works

Candida, the Opportunistic Human Pathogen

Shahabudin, S., & Azmi, N. S. (2020) · Materials science forum · doi:10.4028/www.scientific.net/msf.981.309 · Cited by 1 · see citing works

Drug resistance in pathogenic species of Candida

Jaiswal, N., & Kumar, A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91643-1.00014-4 · Cited by 1 · see citing works

Use of Novel Tools to Probe Drug Resistance in Fungi

Zhao, Y., & Perlin, D. S. (2017) · Springer eBooks · doi:10.1007/978-1-4939-0694-9_21 · Cited by 1 · see citing works

In Vitro and In Vivo Effects of 14α-Demethylase ( ERG11 ) Depletion in Candida glabrata

Nakayama, H., Nakayama, N., Arisawa, M., & Aoki, Y. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.11.3037-3045.2001 · Cited by 39 · see citing works

Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility

Geber, A., Hitchcock, C. A., Swartz, J. E., Pullen, F. S., Marsden, K. E., Kwon-Chung, K. J., & Bennett, J. E. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.12.2708 · Cited by 203 · see citing works

A Clinical Isolate of <i>Candida albicans</i> with Mutations in <i>ERG11</i> (Encoding Sterol 14α-Demethylase) and <i>ERG5</i> (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B

Martel, C. M., Parker, J. E., Bader, O., Weig, M., Gross, U., Warrilow, A. G. S., Kelly, D. E., & Kelly, S. L. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00303-10 · Cited by 165 · see citing works

Multiple mechanisms impact fluconazole resistance of mutant Erg11 proteins in Candida glabrataPreprint

Vu, B. G., & Moye-Rowley, S. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.23.449691 · Cited by 2 · see citing works

Sterol uptake and sterol biosynthesis act coordinately to mediate antifungal resistance in Candida�glabrata under azole and hypoxic stress

Li, Q., Tsai, H., Mandal, A., Walker, B., Noble, J., Fukuda, Y., & Bennett, J. E. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.8716 · Cited by 33 · see citing works