Placenta: The Forgotten Organ

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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.

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The Evolution of Parental Care

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The Evolution of Parental Care

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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

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The Pathology of the Human Placenta

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Preterm labor: One syndrome, many causes

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Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis

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The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

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HIF-1: upstream and downstream of cancer metabolism

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Promotion of Trophoblast Stem Cell Proliferation by FGF4

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Mechanisms of implantation: strategies for successful pregnancy

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The developmental role of serotonin: news from mouse molecular genetics

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Placental development: Lessons from mouse mutants

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The Uterine Spiral Arteries In Human Pregnancy: Facts and Controversies

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Interaction between Oct3/4 and Cdx2 Determines Trophectoderm Differentiation

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Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst

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The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

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Serine and glycine metabolism in cancer

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The Hyperglycemia and Adverse Pregnancy Outcome Study

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Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

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Regulation of Human Placental Development by Oxygen Tension

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The role of the spiral arteries in the pathogenesis of pre-eclampsia.

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Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy

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2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF

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An Envelope Glycoprotein of the Human Endogenous Retrovirus HERV-W Is Expressed in the Human Placenta and Fuses Cells Expressing the Type D Mammalian Retrovirus Receptor

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Cyclin E Ablation in the Mouse

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Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface

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Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3

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Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome

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Eomesodermin is required for mouse trophoblast development and mesoderm formation

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Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

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A transient placental source of serotonin for the fetal forebrain

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Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia.

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Viviparity: The Maternal-Fetal Relationship in Fishes

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Extracorporeal Membrane Oxygenation (ECMO) Cardiopulmonary Support in Infancy

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Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

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Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions?

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Endogenous retroviruses function as species-specific enhancer elements in the placenta

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Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

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A genetic mechanism for Tibetan high-altitude adaptation

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The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta

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Transposon-mediated rewiring of gene regulatory networks contributed to the evolution of pregnancy in mammals

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The expectant brain: adapting for motherhood

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Placental but Not Heart Defects Are Associated with Elevated Hypoxia-Inducible Factor α Levels in Mice Lacking Prolyl Hydroxylase Domain Protein 2

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Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta

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Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

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Direct protein–protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegansPreprint

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Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes

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Pathology of the Human Placenta

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The hyperlipidemia of pregnancy in normal and complicated pregnancies

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Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5

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Autism Spectrum Disorders in Extremely Preterm Children

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Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene

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Regulation of vascular growth and function in the human placenta

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Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

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Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse

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Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth

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The effect of high altitude and other risk factors on birthweight: independent or interactive effects?

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The pattern of interstitial trophoblasticinvasion of the myometrium in early human pregnancy

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Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling

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Doppler ultralsound of the uterine arteries: the importance of bilateral notching in the prediction of pre‐eclampsia, placental abruption or delivery of a small‐for‐gestational‐age baby

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Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1

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Pregnancy: a stress test for life

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Evolution of the mammalian placenta revealed by phylogenetic analysis

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Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury

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Trophectoderm Lineage Determination in Cattle

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Glucose transporter protein expression in human placenta throughout gestation and in intrauterine growth retardation.

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Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain

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Development and function of trophoblast giant cells in the rodent placenta

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Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling

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Fasting serum triglycerides, free fatty acids, and malondialdehyde are increased in preeclampsia, are positively correlated, and decrease within 48 hours post partum

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The placenta: transcriptional, epigenetic, and physiological integration during development

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Progesterone exerts neuroprotective effects after brain injury

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Defective trophoblast function in mice with a targeted mutation of Ets2Preprint

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Intrauterine Growth Restriction, Preeclampsia, and Intrauterine Mortality at High Altitude in Bolivia

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Oxygen, the Janus gas; its effects on human placental development and function

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Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes

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A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy

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Methods of assessing extinction risk in marine fishes

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Placental programming of chronic diseases, cancer and lifespan: A review

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The evolution of parental care in fishes, with reference to Darwin's rule of male sexual selection

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Evaluation of Cell Viability and Functionality in Vessel-like Bioprintable Cell-Laden Tubular Channels

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Ancient Transposable Elements Transformed the Uterine Regulatory Landscape and Transcriptome during the Evolution of Mammalian Pregnancy

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Four-cell stage mouse blastomeres have different developmental properties

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Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

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Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms‐like tyrosine kinase 1 and soluble endoglin in the prediction of pre‐eclampsia: a systematic review and meta‐analysis

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Regulation of Placental Angiogenesis

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Maternal body-volume as a constraint on reproductive output in lizards: evidence from the evolution of viviparity

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Procoagulant and Anticoagulant Mechanisms in Human Placenta

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Ets2 is necessary in trophoblast for normal embryonic anteroposterior axis development

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Receptor-mediated uptake and transport of macromolecules in the human placenta

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Pre-eclampsia is associated with an increase in trophoblast glycogen content and glycogen synthase activity, similar to that found in hydatidiform moles.

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Mechanisms of trophectoderm fate specification in preimplantation mouse development

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Cloning, expression analysis, and chromosomal localization of murine and human homologues of aXenopus Mix gene

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Calponin 3 Regulates Actin Cytoskeleton Rearrangement in Trophoblastic Cell Fusion

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Trophoblast expression of fms-like tyrosine kinase 1 is not required for the establishment of the maternal–fetal interface in the mouse placenta

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Microtubules and biotic interactions

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Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placentaPreprint

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Trophoblast development

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Single-cell reconstruction of the early maternal–fetal interface in humans

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Pathophysiology from preconception, during pregnancy, and beyond.

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Single-Cell RNA-seq Identifies Cell Subsets in Human Placenta That Highly Expresses Factors Driving Pathogenesis of SARS-CoV-2

Ashary, N., Bhide, A., Chakraborty, P., Colaco, S., Mishra, A., Chhabria, K., Jolly, M. K., & Modi, D. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00783 · Cited by 121 · see citing works

Praegnatio Perturbatio—Impact of Endocrine-Disrupting Chemicals

Padmanabhan, V., Song, W., & Puttabyatappa, M. (2021) · Endocrine Reviews · doi:10.1210/endrev/bnaa035 · Cited by 103 · see citing works

Recent advances in liver engineering with decellularized scaffold

Dai, Q., Jiang, W., Huang, F., Song, F., Zhang, J., & Zhao, H. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.831477 · Cited by 57 · see citing works

Evolving the Era of 5D Ultrasound? A Systematic Literature Review on the Applications for Artificial Intelligence Ultrasound Imaging in Obstetrics and Gynecology

Jost, E., Kosian, P., Jimenez Cruz, J., Albarqouni, S., Gembruch, U., Strizek, B., & Recker, F. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12216833 · Cited by 44 · see citing works

Endocrine-Disrupting Chemicals in Human Fetal Growth

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Human placental extract improves liver cirrhosis in mice with regulation of macrophages and senescent cells

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Conservation at the uterine–placental interface

Scott, R. L., Vu, H., Jain, A., Iqbal, K., Tuteja, G., & Soares, M. J. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2210633119 · Cited by 33 · see citing works

Conservation at the uterine-placental interfacePreprint

Scott, R. L., Vu, H. T. H., Jain, A., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.14.496152 · Cited by 1 · see citing works

The ever growing complexity of trophoblast epigenetics

Schmidt, K. A. (2018)

A simple in vivo approach to investigate invasive trophoblast cells

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The metrial gland is more than a mesometrial lymphoid aggregate of pregnancy

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