The DOI matches its Crossref record; 230 of the 230 references it cites were found in a registry or an index.
Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress
Open accessAbstract
The psychology of extinction has been studied for decades. Approximately 10 years ago, however, there began a concerted effort to understand the neural circuits of extinction of fear conditioning, in both animals and humans. Progress during this period has been facilitated by a high degree of coordination between rodent and human researchers examining fear extinction. Here we review the major advances and highlight new approaches to understanding and exploiting fear extinction. Research in fear extinction could serve as a model for translational research in other areas of behavioral neuroscience.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“A closely related domain of research on conditioning and extinction in both rodents and humans also suggests that ventromedial PFC (vmPFC), an area neighboring rACC, supports extinction while cACC supports increased aversive processing (Milad and Quirk, 2012; see Figure 7).”
From Top-Down Dysregulation—From ADHD to Emotional Instability (2016) · cites this paper as Milad and Quirk, 2012
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“The vmPFC is proposed to be the homologue for the IL in rodents [87] and serves to inhibit threat responses produced by the amygdala.”
From Prefrontal cortex, amygdala, and threat processing: implications for PTSD (2022) · cites this paper as [87]
The cited source says what the claim attributes to it.
In the citing paper
“The vmPFC is thought to modulate amygdala processing of conditioned fear by suppressing fear responses through a set of amygdala neurons in the intercalated region between the basolateral and central amygdala nucleus (Milad and Quirk, 2012).”
From Top-Down Dysregulation—From ADHD to Emotional Instability (2016) · cites this paper as Milad and Quirk, 2012
In the citing paper
“The vmPFC is activated during retrieval of extinction learning and down-regulates the amygdala”
From Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience (2014) · cites this paper as Milad and Quirk, 2012
In the citing paper
“Therefore, in PTSD, there is both hyperactivation of the fear expression and hypoactivation of the extinction memory networks [59, 60].”
From Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory (2015) · cites this paper as [59]
In the citing paper
“However, rather than erasing the CS-US association, extinction represents formation of a new memory, an “extinction memory,” signifying “CS-no US,” that competitively inhibits the memory of the CS-US contingency and expression of its associated CR when the CS is again encountered [51–59].”
From Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory (2015) · cites this paper as [59]
In the citing paper
“A deficit in the ability to encode, consolidate, or retrieve extinction memory is believed to play a role in the development and perpetuation of such disorders [6, 59, 61, 87].”
From Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory (2015) · cites this paper as [59]
In the citing paper
“Neuroimaging research using de novo fear-conditioning and extinction paradigms has revealed areas in the brain associated with experiencing conditioned fear (a “fear expression network”) in the amygdala and dorsal anterior cingulate cortex (dACC) and other areas associated with memory for the extinction (inhibition) of this fear (an “extinction memory network”) that includes the hippocampus and”
From Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory (2015) · cites this paper as [59]
In the citing paper
“Brain circuitry at the core of threat discrimination learning includes areas within the amygdala and medial prefrontal cortex (mPFC)1.”
From Multimodal evidence for delayed threat extinction learning in adolescence and young adulthood (2019) · cites this paper as [1]
In the citing paper
“During threat extinction training, the CS is presented without the aversive outcome, which results in reduced amygdala responses to the CS over time3, with the mPFC playing a critical role1,4,5.”
From Multimodal evidence for delayed threat extinction learning in adolescence and young adulthood (2019) · cites this paper as [1]
In the citing paper
“During threat extinction training, the CS is presented without the aversive outcome, which results in reduced amygdala responses to the CS over time3, with the mPFC playing a critical role1,4,5.”
From Multimodal evidence for delayed threat extinction learning in adolescence and young adulthood (2019) · cites this paper as [1]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S., Quinn, K., Sanislow, C., & Wang, P. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09091379 · Cited by 7,067
Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0135058100 · Cited by 6,358
Psychophysiological and Modulatory Interactions in Neuroimaging
Friston, K. J., Buechel, C., Fink, G. R., Morris, J., Rolls, E., & Dolan, R. J. (1997) · NeuroImage · doi:10.1006/nimg.1997.0291 · Cited by 3,097
Emotional processing in anterior cingulate and medial prefrontal cortex
Etkin, A., Egner, T., & Kalisch, R. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.11.004 · Cited by 3,059 · cited 1×
“Numerous reviews on molecular mechanisms of extinction, clinical relevance, and inhibition circuitry within the amygdala have recently appeared (Pape & Paré 2010, Herry et al 2010, Sotres-Bayon & Quirk 2010, Myers et al 2011, Etkin et al 2011).”
BackgroundTrauma and Posttraumatic Stress Disorder in the Community: The 1996 Detroit Area Survey of Trauma
Breslau, N., Kessler, R. C., Chilcoat, H. D., Schultz, L. R., Davis, G. C., & Andreski, P. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.7.626 · Cited by 2,407
Whalen, P. J., Rauch, S. L., Etcoff, N. L., McInerney, S. C., Lee, M. B., & Jenike, M. A. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00411.1998 · Cited by 2,205
Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network
Greicius, M. D., Supekar, K., Menon, V., & Dougherty, R. F. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn059 · Cited by 2,175
Integrative activity of the brain
Konorski, J. (1967) · University of Chicago Press eBooks · Cited by 2,043
Pezawas, L., Meyer-Lindenberg, A., Drabant, E. M., Verchinski, B. A., Munoz, K. E., Kolachana, B. S., Egan, M. F., Mattay, V. S., Hariri, A. R., & Weinberger, D. R. (2005) · Nature Neuroscience · doi:10.1038/nn1463 · Cited by 1,980
Cited by
Sorted by citations
Items 601–700 of 1,002
Morriss, J., Bell, T., Biagi, N., Johnstone, T., & van Reekum, C. M. (2021) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-021-00932-7 · Cited by 28
Contextual modulation of conditioned responses in humans: A review on virtual reality studies
Andreatta, M., & Pauli, P. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102095 · Cited by 27
Keller, N. E., Hennings, A. C., Leiker, E., Lewis‐Peacock, J. A., & Dunsmoor, J. E. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0075-22.2022 · Cited by 30
Kelly, T. J., Bonniwell, E. M., Mu, L., Liu, X., Hu, Y., Friedman, V., Yu, H., Su, W., McCorvy, J. D., & Liu, Q.-S. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01744-8 · Cited by 29
Serotonergic, Brain Volume and Attentional Correlates of Trait Anxiety in Primates
Mikheenko, Y., Shiba, Y., Sawiak, S. J., Braesicke, K., Cockcroft, G. J., Clarke, H. F., & Roberts, A. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.324 · Cited by 30
Behavioral disruption of memory reconsolidation: From bench to bedside and back again.
Drexler, S. M., & Wolf, O. T. (2018) · Behavioral Neuroscience · doi:10.1037/bne0000231 · Cited by 29
Oxytocin for learning calm and safety
Eckstein, M., de Minas, A. C. A., Scheele, D., Kreuder, A., Hurlemann, R., Grinevich, V., & Ditzen, B. (2018) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2018.06.004 · Cited by 28
Dorsal Hippocampus to Infralimbic Cortex Circuit is Essential for the Recall of Extinction Memory
Qin, C., Bian, X.-L., Wu, H., Xian, J.-Y., Cai, C.-Y., Lin, Y., Zhou, Y., Kou, X., Chang, L., Luo, C., et al. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa320 · Cited by 27
The case for hemispheric lateralization of the human amygdala in fear processing
Xie, T., van Rooij, S. J. H., Inman, C. S., Wang, S., Brunner, P., & Willie, J. T. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02940-2 · Cited by 26
Trent, S., Abdullah, M. H., Parwana, K., Valdivieso, M. A., Hassan, Z., & Müller, C. P. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111310 · Cited by 33
How Positive and Negative Expectations Shape the Experience of Visceral Pain
Elsenbruch, S. (2014) · Handbook of experimental pharmacology · doi:10.1007/978-3-662-44519-8_6 · Cited by 26
Bolkan, S. S., & Lattal, K. M. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.12.009 · Cited by 28
Contextual Fear Conditioning and Fear Generalization in Individuals With Panic Attacks
Neueder, D., Andreatta, M., & Pauli, P. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00152 · Cited by 26
Fear extinction learning and retention during adolescence in rats and mice: A systematic review
Bisby, M. A., Stylianakis, A. A., Baker, K., & Richardson, R. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.10.044 · Cited by 26
Lucifora, C., Grasso, G. M., Nitsche, M. A., D'Italia, G., Sortino, M., Salehinejad, M. A., Falzone, A., Avenanti, A., & Vicario, C. M. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.05.033 · Cited by 26
Neural Oscillations in Aversively Motivated Behavior
Totty, M. S., & Maren, S. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.936036 · Cited by 28
Maywald, M., Pogarell, O. M., Levai, S., Paolini, M., Tschentscher, N., Rauchmann, B., Krause, D., Stoecklein, S., Goerigk, S. A., Röll, L., et al. (2023) · NeuroImage Clinical · doi:10.1016/j.nicl.2023.103330 · Cited by 26
Rahimi-Danesh, M., Samizadeh, M., Sajadi, A.-E., Rezvankhah, T., & Vaseghi, S. (2023) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2023.173675 · Cited by 26
Broadwater, M., & SPEAR, L. P. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.06.029 · Cited by 26
Animal Paradigms to Assess Cognition with Translation to Humans
Wallace, T. L., Ballard, T. M., & Glavis-Bloom, C. (2015) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-319-16522-6_2 · Cited by 26
Erasure of fear memories is prevented by Nogo Receptor 1 in adulthood
Bhagat, S. M., Butler, S. S., Taylor, J. R., McEwen, B. S., & Strittmatter, S. M. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.179 · Cited by 28
Ernst, T., Thürling, M., Muller, S. M., Kahl, F., Maderwald, S., Schlamann, M. U., Boele, H., Koekkoek, S. K. E., Diedrichsen, J., Zeeuw, C. I. D., et al. (2017) · Human Brain Mapping · doi:10.1002/hbm.23641 · Cited by 26
Basolateral amygdala calpain is required for extinction of contextual fear-memory
Song, Z., Chen, H., Xu, W., Wu, S.-B., & Zhu, G. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.08.004 · Cited by 26
Liu, C., Xu, L., Li, J., Zhou, F., Yang, X., Zheng, X., Fu, M., Li, K., Sindermann, C., Montag, C., et al. (2020) · Psychological Medicine · doi:10.1017/s0033291720002809 · Cited by 26
Cingulate subregions in posttraumatic stress disorder, chronic stress, and treatment
Hinojosa, C. A., Kaur, N., VanElzakker, M. B., & Shin, L. M. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64196-0.00020-0 · Cited by 26
Tsotsokou, G., Νικολακοπούλου, Μ., Kouvelas, E. D., & Mitsacos, A. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15358 · Cited by 25
Cano, M., Lee, E. G., Worthley, A., Ellard, K. K., Barbour, T. A., Soriano‐Mas, C., & Camprodon, J. A. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.06.062 · Cited by 25
Prefrontal cortical circuits in anxiety and fear: an overview
Chen, Y., Hu, N.-Y., Yang, J., & Gao, T. (2022) · Frontiers of Medicine · doi:10.1007/s11684-022-0941-2 · Cited by 29
Translational Approaches to Anxiety: Focus on Genetics, Fear Extinction and Brain Imaging
Erhardt, A., & Spoormaker, V. I. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-013-0417-9 · Cited by 27
André, M. A. E., Güntürkün, O., & Manahan‐Vaughan, D. (2014) · Hippocampus · doi:10.1002/hipo.22359 · Cited by 25
Stuber, G. D., & Mason, A. O. (2013) · Pharmacological Reviews · doi:10.1124/pr.111.005611 · Cited by 26
Comparative study of group treatments for posttraumatic stress disorder.
Maxwell, K., Callahan, J. L., Holtz, P. M., Janis, B. M., Gerber, M. M., & Connor, D. R. (2015) · Psychotherapy · doi:10.1037/pst0000032 · Cited by 25
Learning mechanisms underlying threat absence and threat relief: Influences of trait anxiety
Andreatta, M., & Pauli, P. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.09.005 · Cited by 25
Río, R. T.-D., van den Burg, E. H., Stoop, R., & Hegoburu, C. (2018) · Psychopharmacology · doi:10.1007/s00213-018-5030-5 · Cited by 26
Innovations in the delivery of exposure and response prevention for obsessive-compulsive disorder
Patel, S. R., Comer, J., & Simpson, H. B. (2021) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2020_202 · Cited by 24
Transcutaneous Auricular Vagus Nerve Stimulation to Improve Emotional State
Ruiz, A. A. (2024) · Biomedicines · doi:10.3390/biomedicines12020407 · Cited by 24
Gu, Y., & Zhu, D. (2021) · Journal of Biomedical Research · doi:10.7555/jbr.34.20200108 · Cited by 24
Chandler, L. J., Vaughan, D. T., & Gass, J. T. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.837657 · Cited by 24
A Case for Translation From the Clinic to the Laboratory
Kredlow, M. A., de Voogd, L. D., & Phelps, E. A. (2022) · Perspectives on Psychological Science · doi:10.1177/17456916211039852 · Cited by 25
Obesity-Associated Anxiety Is Prevalent among College Students and Alleviated by Calorie Restriction
Wang, J., Ran, X., Ye, J., Deng, R., Dang, W., Fan, Y., Hu, Z., Yang, L., Dong, W., Lv, Y., et al. (2022) · Nutrients · doi:10.3390/nu14173518 · Cited by 24
Spontaneous recovery of reward memory through active forgetting of extinction memory
Yang, Q., Zhou, J. W., Wang, L., Hu, W., Zhong, Y., & Li, Q. (2023) · Current Biology · doi:10.1016/j.cub.2023.01.022 · Cited by 24
Hippocampal Engrams Generate Variable Behavioral Responses and Brain-Wide Network States
Dorst, K. E., Senne, R. A., Diep, A. H., de Boer, A. R., Suthard, R. L., Leblanc, H., Ruesch, E. A., Pyo, A. Y., Skelton, S., Carstensen, L. C., et al. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0340-23.2023 · Cited by 26
Sjouwerman, R., Niehaus, J., & Lonsdorf, T. B. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00337 · Cited by 24
Javanbakht, A., Duval, E. R., Cisneros, M. E., Taylor, S. F., Kessler, D. A., & Liberzon, I. (2016) · Cognition & Emotion · doi:10.1080/02699931.2016.1169997 · Cited by 24
Feng, P., Zheng, Y., & Feng, T. (2015) · Scientific Reports · doi:10.1038/srep16701 · Cited by 24
Levin, N., Kritman, M., Maroun, M., & Akirav, I. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.06.007 · Cited by 24
Age-Related Decrease in Stress Responsiveness and Proactive Coping in Male Mice
Oh, H.-J., Song, M., Kim, Y. K., Bae, J. R., Cha, S.-Y., Bae, J. Y., Kim, Y., You, M., Lee, Y., Shim, J., et al. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00128 · Cited by 24
Hollandt, M., Wroblewski, A., Yang, Y., Ridderbusch, I. C., Kircher, T. T. J., Hamm, A. O., Straube, B., & Richter, J. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0786-x · Cited by 24
Bublatzky, F., Guerra, P. M., & Alpers, G. W. (2020) · Cortex · doi:10.1016/j.cortex.2020.07.009 · Cited by 25
Jamieson, A. J., Davey, C. G., & Harrison, B. J. (2021) · eNeuro · doi:10.1523/eneuro.0380-20.2021 · Cited by 25
Roesmann, K., Kroker, T., Hein, S., Rehbein, M. A., Winker, C., Leehr, E. J., Klucken, T., & Junghöfer, M. (2021) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2021.08.001 · Cited by 24
Lonsdorf, T. B., Haaker, J., Fadai, T., & Kalisch, R. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3338-8 · Cited by 27
Andreatta, M., Neueder, D., Glotzbach-Schoon, E., Mühlberger, A., & Pauli, P. (2016) · Learning & Memory · doi:10.1101/lm.044073.116 · Cited by 24
Multiple faces of anxiety: a frontal lobe perspective
Roberts, A., & Mulvihill, K. G. (2024) · Trends in Neurosciences · doi:10.1016/j.tins.2024.07.001 · Cited by 23
de Sá, D. S. F., Römer, S., Brueckner, A. H., Issler, T. C., Hauck, A., & Michael, T. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-019-0593-3 · Cited by 24
Icenhour, A., Petrakova, L., Hazzan, N., Theysohn, N., Merz, C. J., & Elsenbruch, S. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118229 · Cited by 23
Sisk, L. M., Rapuano, K. M., Conley, M. I., Greene, A. S., Horien, C. L., Rosenberg, M. D., Scheinost, D., Constable, R. T., Glatt, C. E., Casey, B. J., et al. (2021) · Journal of Neuroscience Research · doi:10.1002/jnr.24946 · Cited by 24
Presto, P., Ji, G., Junell, R., Griffin, Z., & Neugebauer, V. (2021) · Brain Sciences · doi:10.3390/brainsci11101339 · Cited by 23
Szeska, C., Pünjer, H., Riemann, S., Meinzer, M., & Hamm, A. O. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02174-8 · Cited by 24
Augmentation of Evidence-Based Psychotherapy for PTSD With Cognitive Enhancers
Marin, M., Lonak, S. F., & Milad, M. R. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-015-0582-0 · Cited by 24
Self-citationPain predictability reverses valence ratings of a relief-associated stimulus
Andreatta, M., Mühlberger, A., Glotzbach-Schoon, E., & Pauli, P. (2013) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2013.00053 · Cited by 26
Corticosteroid–endocannabinoid loop supports decrease of fear-conditioned response in rats
de Bitencourt, R. M., Pamplona, F. A., & Takahashi, R. N. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.01.010 · Cited by 23
Gass, J. T., McGonigal, J. T., & Chandler, L. J. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.10.005 · Cited by 24
Glenn, D. E., Risbrough, V. B., Simmons, A. N., Acheson, D. T., & Stout, D. M. (2017) · Current topics in behavioral neurosciences · doi:10.1007/7854_2017_30 · Cited by 23
Rabinak, C. A., Peters, C., Marusak, H. A., Ghosh, S., & Phan, K. L. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.10.002 · Cited by 23
Context-dependent generalization of conditioned responses to threat and safety signals
Andreatta, M., Genheimer, H., Wieser, M. J., & Pauli, P. (2020) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2020.06.006 · Cited by 23
Bijsterbosch, J. D., Smith, S. M., & Bishop, S. J. (2015) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00825 · Cited by 25
Compound stimulus extinction reduces spontaneous recovery in humansPreprint
Coelho, C. A. O., Dunsmoor, J. E., & Phelps, E. A. (2015) · Learning & Memory · doi:10.1101/lm.039479.115 · Cited by 23
Prepared stimuli enhance aversive learning without weakening the impact of verbal instructionsPreprint
Atlas, L. Y., & Phelps, E. A. (2018) · Learning & Memory · doi:10.1101/lm.046359.117 · Cited by 26
Stawicka, Z. M., Massoudi, R., Horst, N. K., Koda, K., Gaskin, P. L. R., Alexander, L., Santangelo, A. M., McIver, L., Cockcroft, G. J., Wood, C. M., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2009657117 · Cited by 22
Chauret, M., Suffren, S., Pine, D. S., Nassim, M., Saint‐Amour, D., & Maheu, F. S. (2019) · Biological Psychology · doi:10.1016/j.biopsycho.2019.107744 · Cited by 22
Psychophysiological evidence for fear extinction learning via mental imagery
Jiang, X., & Greening, S. G. (2021) · Psychophysiology · doi:10.1111/psyp.13906 · Cited by 22
Zaizar, E. D., Papini, S., Gonzalez-Lima, F., & Telch, M. J. (2021) · Psychological Medicine · doi:10.1017/s0033291721002270 · Cited by 22
Zabik, N. L., Rabinak, C. A., Peters, C. A., & Iadipaolo, A. S. (2023) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2023.107758 · Cited by 22
Yamamori, Y., Robinson, O. J., & Roiser, J. P. (2023) · eLife · doi:10.7554/elife.87720 · Cited by 26
Reynolds, G., Field, A. P., & Askew, C. (2016) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2016.1138410 · Cited by 22
Baker, K., & Richardson, R. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.10.014 · Cited by 22
Carlisi, C. O., Hilbert, K., Guyer, A. E., & Ernst, M. (2017) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-017-0535-7 · Cited by 22
Structural covariance network centrality in maltreated youth with posttraumatic stress disorder
Sun, D., Peverill, M., Swanson, C. A., McLaughlin, K. A., & Morey, R. A. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.12.015 · Cited by 22
Individual variation in working memory is associated with fear extinction performance
Stout, D. M., Acheson, D. T., Moore, T. M., Gur, R. C., Baker, D. G., Geyer, M. A., & Risbrough, V. B. (2018) · Behaviour Research and Therapy · doi:10.1016/j.brat.2018.01.002 · Cited by 22
Neural correlates of subjective CS/UCS association in appetitive conditioning
León, I. T., Kruse, O., Stalder, T., Stark, R. M., & Klucken, T. (2018) · Human Brain Mapping · doi:10.1002/hbm.23940 · Cited by 23
Barredo, J., Aiken, E., Wout‐Frank, M. V. ‘., Greenberg, B. D., Carpenter, L. L., & Philip, N. S. (2018) · Brain Connectivity · doi:10.1089/brain.2018.0634 · Cited by 23
Jacques, A., Chaaya, N., Hettiarachchi, C., Carmody, M.-L., Beecher, K., Belmer, A., Chehrehasa, F., Bartlett, S. E., Battle, A. R., & Johnson, L. R. (2019) · Psychopharmacology · doi:10.1007/s00213-018-5068-4 · Cited by 22
Boukezzi, S. C., Baunez, C., Rousseau, P., Warrot, D., Silva, C., Guyon, V., Zendjidjian, X. Y., Nicolas, F., Guedj, É., Nazarian, B., et al. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.102073 · Cited by 26
Gonzalez, S. T., & Fanselow, M. S. (2020) · Psychology & Neuroscience · doi:10.1037/pne0000207 · Cited by 27
Vermes, J. S., Ayres, R., Goés, A. S., Real, N. D., Araújo, Á. C., Schiller, D., Neto, F. L., & Corchs, F. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.06.052 · Cited by 24
Wen, Z., Hammoud, M. Z., Scott, J. C., Jimmy, J., Brown, L. A., Marin, M., Asnaani, A., Gur, R. C., Foa, E. B., & Milad, M. R. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01158-4 · Cited by 23
Self-citationIndividual differences in fear relapse
King, G., Graham, B. M., & Richardson, R. (2017) · Behaviour Research and Therapy · doi:10.1016/j.brat.2017.11.003 · Cited by 22
Diverse Effects of Conditioned Threat Stimuli on BehaviorPreprint
Moscarello, J. M., & LeDoux, J. E. (2014) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2014.79.024968 · Cited by 24
How Psychedelics Modulate Multiple Memory Mechanisms in Posttraumatic Stress Disorder
Doss, M. K., DeMarco, A., Dunsmoor, J. E., Cisler, J. M., Fonzo, G. A., & Nemeroff, C. B. (2024) · Drugs · doi:10.1007/s40265-024-02106-4 · Cited by 24
Bender, C. L., Otamendi, A., Calfa, G. D., & Molina, V. A. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.12.003 · Cited by 21
Ferreira, F. F., Rodrigues, F. D. S., Schmidt, S. D., Cavalcante, L. E. S., Zinn, C. G., Farias, C. P., Furini, C. R. G., Myskiw, J. D. C., & Izquierdo, I. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134505 · Cited by 21
Different methods of fear reduction are supported by distinct cortical substrates
Lay, B. P. P., Pitaru, A. A., Boulianne, N., Esber, G. R., & Iordanova, M. D. (2020) · eLife · doi:10.7554/elife.55294 · Cited by 21
Glavonic, E., Mitić, M., & Adžić, M. (2022) · Journal of Neuroscience Research · doi:10.1002/jnr.25017 · Cited by 21
Antolasic, E. J., Jaehne, E. J., & van den Buuse, M. (2023) · Current Neuropharmacology · doi:10.2174/1570159x21666230724101321 · Cited by 22
Corticolimbic catecholamines in stress: a computational model of the appraisal of controllability
Fiore, V. G., Mannella, F., Mirolli, M., Latagliata, E. C., Valzania, A., Cabib, S., Dolan, R. J., Puglisi‐Allegra, S., & Baldassarre, G. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0727-7 · Cited by 21
Lengersdorf, D., Marks, D., Uengoer, M., Stüttgen, M. C., & Güntürkün, O. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00085 · Cited by 25
Natividad, L. A., Steinman, M. Q., Laredo, S. A., Irimia, C., Polis, I. Y., Lintz, R., Buczynski, M. W., Martin‐Fardon, R., Roberto, M., & Parsons, L. H. (2017) · Addiction Biology · doi:10.1111/adb.12568 · Cited by 22
Boskovic, Z., Milne, M., Qian, L., Clifton, H. D., McGovern, A. E., Turnbull, M. T., Mazzone, S. B., & Coulson, E. J. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0248-x · Cited by 21
Metadata
- Authors
- Milad, M. R., & Quirk, G. J.
- Affiliations
- Harvard University (US)
- University of Puerto Rico, Medical Sciences Campus (PR)
- Venue
- Annual Review of Psychology
- Publisher
- Annual Reviews
- Published
- 2012-01-10
- Volume
- 63
- Issue
- 1
- Pages
- 129-151
- ISSN
- 0066-4308 (ISSN-L)
- 1545-2085
- PMC
- PMC4942586
- OpenAlex
- W2160253364
- Semantic Scholar
- 3e1b47b5a0d8ab9823c918aa6f6ce64eb2eba033
- Cited by
- 1,466
- References
- 228
- Citations by year
- 2026: 105 · 2025: 96 · 2024: 80 · 2023: 96 · 2022: 110 · 2021: 114 · 2020: 131 · 2019: 120 · 2018: 109 · 2017: 102 · 2016: 100 · 2015: 105 · 2014: 88 · 2013: 73 · 2012: 36
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annual Review of Psychology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5p50mh086400-05, 5r01mh081975-05)
- National Institute of Mental Health (P-50-MH-086400, K01-MH08036, R01-MH081975, R01MH058883, K01MH080346)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- fear extinction, fear conditioning, neural circuits, translational neuroscience, psychobiology, anxiety disorders
- MeSH terms
- Brain, Conditioning, Psychological, Extinction, Psychological, Fear, Humans, Magnetic Resonance Imaging, Neurosciences
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
