Carbohydrate Ingestion during Exercise: Effects on Performance, Training Adaptations and Trainability of the Gut
Abstract
Carbohydrate feeding has been shown to enhance endurance performance. During exercise of 2 h or more, the delivery of carbohydrates to the muscle is the crucial step and appears to be limited by intestinal absorption. It is therefore important to identify ways to overcome this limitation and study the positive and negative effects of chronic carbohydrate supplementation. There is evidence that intestinal absorption can, at least partly, be overcome by making use of multiple transportable carbohydrates. Ingestion of these carbohydrates may result in higher intestinal absorption rates and has been shown to lead to higher rates of exogenous carbohydrate oxidation which can result in better endurance performance. It also seems possible to increase the absorptive capacity of the intestine by adapting to a high-carbohydrate diet. Carbohydrate supplementation during exercise has been suggested to reduce training adaptations, but at present there is little or no evidence to support this. Despite the fact that it has long been known that carbohydrate supplementation can enhance endurance performance, there are still many unanswered questions. However, there is potential to develop strategies that enhance the delivery of carbohydrates and thereby improve endurance performance.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In longer events, ingesting carbohydrates and increasing exogenous carbohydrate oxidation improves endurance performance in most events.
“In longer events, it is clear that ingesting carbohydrates and increasing exogenous carbohydrate oxidation will result in improved endurance performance in most events [38–41, 68].”
From Periodized Nutrition for Athletes (2017) · cites this paper as [68]
Cites
Diet, muscle glycogen and physical performance.
Bergström, J., Hermansen, L., Hultman, E., & Saltin, B. (1967) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1967.tb03720.x · Cited by 1,740 · see citing works
Nutrition and Athletic Performance
(2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31890eb86 · Cited by 1,084 · see citing works
Expression cloning and cDNA sequencing of the Na+/glucose co-transporter
Hediger, M. A., Coady, M. J., Ikeda, T. S., & Wright, E. M. (1987) · Nature · doi:10.1038/330379a0 · Cited by 1,004 · see citing works
Validity, Reliability and Sensitivity of Measures of Sporting Performance
Currell, K., & Jeukendrup, A. E. (2008) · Sports Medicine · doi:10.2165/00007256-200838040-00003 · Cited by 786 · see citing works
Self-citationThorens, B., Sarkar, H. K., Kaback, H. R., & Lodish, H. F. (1988) · Cell · doi:10.1016/0092-8674(88)90051-7 · Cited by 785 · see citing works
Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
Winder, W. W., Holmes, B. F., Rubink, D. S., Jensen, E. B., Chen, M., & Holloszy, J. O. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.6.2219 · Cited by 709 · see citing works
Fructose transporter in human spermatozoa and small intestine is GLUT5.
Burant, C., Takeda, J., Brot‐Laroche, E., Bell, G. I., & Davidson, N. O. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42067-4 · Cited by 545 · see citing works
Holmes, B. F., Kurth-Kraczek, E. J., & Winder, W. W. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.87.5.1990 · Cited by 489 · see citing works
The Relative Value of Fat and Carbohydrate as Sources of Muscular Energy
Krogh, A., & Lindhard, J. (1920) · Biochemical Journal · doi:10.1042/bj0140290 · Cited by 411 · see citing works
Dietary and developmental regulation of intestinal sugar transport
Ferraris, R. P. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3600265 · Cited by 328 · see citing works
Oxidation of combined ingestion of glucose and fructose during exercise
Jentjens, R. L. P. G., Moseley, L., Waring, R. H., Harding, L. K., & Jeukendrup, A. E. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00974.2003 · Cited by 310 · see citing works
Self-citationThe facilitated component of intestinal glucose absorption
Kellett, G. L. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.0585h.x · Cited by 294 · see citing works
Skeletal muscle adaptation: training twice every second day vs. training once daily
Hansen, A. K., Fischer, C. P., Plomgaard, P., Andersen, J. L., Saltin, B., & Pedersen, B. K. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00163.2004 · Cited by 286 · see citing works
Yeo, W. K., Paton, C. D., Garnham, A. P., Burke, L. M., Carey, A. L., & Hawley, J. A. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90882.2008 · Cited by 283 · see citing works
Jeukendrup, A. E., & Jentjens, R. (2000) · Sports Medicine · doi:10.2165/00007256-200029060-00004 · Cited by 279 · see citing works
Self-citationRegulation of intestinal sugar transport
Ferraris, R. P., & Diamond, J. S. (1997) · Physiological Reviews · doi:10.1152/physrev.1997.77.1.257 · Cited by 274 · see citing works
Luminal glucose concentrations in the gut under normal conditions
Ferraris, R. P., Yasharpour, S., Lloyd, K. C. K., Mirzayan, R., & Diamond, J. M. (1990) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1990.259.5.g822 · Cited by 270 · see citing works
Superior Endurance Performance with Ingestion of Multiple Transportable Carbohydrates
CURRELL, K., & JEUKENDRUP, A. E. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31815adf19 · Cited by 243 · see citing works
Self-citationCarbohydrate and exercise performance: The role of multiple transportable carbohydrates
Jeukendrup, A. E. (2010) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e328339de9f · Cited by 212 · see citing works
Self-citationTraining with Low Muscle Glycogen Enhances Fat Metabolism in Well-Trained Cyclists
HULSTON, C. J., VENABLES, M. C., MANN, C. H., MARTIN, C., PHILP, A., BAAR, K., & JEUKENDRUP, A. E. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181dd5070 · Cited by 196 · see citing works
Self-citationJentjens, R. L. P. G., & Jeukendrup, A. E. (2005) · British Journal of Nutrition · doi:10.1079/bjn20041368 · Cited by 171 · see citing works
Self-citationCox, G. R., Clark, S. A., Cox, A. J., Halson, S. L., Hargreaves, M., Hawley, J. A., Jeacocke, N., Snow, R. J., Yeo, W. K., & Burke, L. M. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00950.2009 · Cited by 165 · see citing works
Muscle Glycogen Synthesis in Relation to Diet Studied in Normal Subjects
Hultman, E., & Bergström, J. P. (1967) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1967.tb11504.x · Cited by 156 · see citing works
High Oxidation Rates from Combined Carbohydrates Ingested during Exercise
JENTJENS, R. L. P. G., ACHTEN, J., & JEUKENDRUP, A. E. (2004) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000139796.07843.1d · Cited by 153 · see citing works
Self-citationEffects of carbohydrate type and concentration and solution osmolality on water absorption
Shi, X., Summers, R. W., Schedl, H. P., Flanagan, S. W., CHANG, R., & GISOLFI, C. V. (1995) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199512000-00005 · Cited by 150 · see citing works
Exogenous carbohydrate oxidation during ultraendurance exercise
Jeukendrup, A. E., Moseley, L., Mainwaring, G. I., Samuels, S., Perry, S., & Mann, C. H. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00981.2004 · Cited by 147 · see citing works
Self-citationOxidation of Combined Ingestion of Maltodextrins and Fructose during Exercise
WALLIS, G. A., ROWLANDS, D. S., SHAW, C., JENTJENS, R. L. P. G., & JEUKENDRUP, A. E. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000155399.23358.82 · Cited by 134 · see citing works
Self-citationOxidation of exogenous glucose, sucrose, and maltose during prolonged cycling exercise
Jentjens, R. L. P. G., Venables, M. C., & Jeukendrup, A. E. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01023.2003 · Cited by 134 · see citing works
Self-citationJentjens, R. L. P. G., Underwood, K., Achten, J., Currell, K., Mann, C. H., & Jeukendrup, A. E. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00322.2005 · Cited by 125 · see citing works
Self-citationCarbohydrate feeding during exercise
Jeukendrup, A. E. (2008) · European Journal of Sport Science · doi:10.1080/17461390801918971 · Cited by 115 · see citing works
Self-citationMoran, A. W., Al-Rammahi, M. A., Arora, D. K., Batchelor, D. J., Coulter, E. A., Daly, K., Ionescu, C., Bravo, D., & Shirazi-Beechey, S. P. (2010) · British Journal of Nutrition · doi:10.1017/s0007114510000917 · Cited by 114 · see citing works
Multiple transportable carbohydrates enhance gastric emptying and fluid delivery
Jeukendrup, A. E., & Moseley, L. (2010) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/j.1600-0838.2008.00862.x · Cited by 113 · see citing works
Self-citationSmith, J. W., Zachwieja, J. J., Péronnet, F., Passe, D. H., Massicotte, D., Lavoie, C., & Pascoe, D. D. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91394.2008 · Cited by 103 · see citing works
Civitarese, A. E., Hesselink, M. K. C., Russell, A. P., Ravussin, E., & Schrauwen, P. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00193.2005 · Cited by 99 · see citing works
Oxidation of combined ingestion of glucose and sucrose during exercise
Jentjens, R. L. P. G., Shaw, C. S., Birtles, T., Waring, R. H., Harding, L. K., & Jeukendrup, A. E. (2005) · Metabolism · doi:10.1016/j.metabol.2004.12.004 · Cited by 94 · see citing works
Self-citationIntestinal glucose sensing and regulation of intestinal glucose absorption
Dyer, J., Daly, K., Salmon, K. S. H., Arora, D. K., Kokrashvili, Z., Margolskee, R. F., & Shirazi‐Beechey, S. P. (2007) · Biochemical Society Transactions · doi:10.1042/bst0351191 · Cited by 85 · see citing works
Triplett, D., Doyle, J. A., Rupp, J. C., & Benardot, D. (2010) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.20.2.122 · Cited by 75 · see citing works
Akerstrom, T. C. A., Birk, J. B., Klein, D. K., Erikstrup, C., Plomgaard, P., Pedersen, B. K., & Wojtaszewski, J. F. P. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.057 · Cited by 75 · see citing works
Oxidation of Solid versus Liquid CHO Sources during Exercise
Pfeiffer, B., Stellingwerff, T., Zaltas, E., & Jeukendrup, A. E. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181e0efc9 · Cited by 75 · see citing works
Self-citationROWLANDS, D. S., Thorburn, M. S., Thorp, R. M., Broadbent, S., & Shi, X. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00878.2007 · Cited by 71 · see citing works
Human intestinal water absorption: direct vs. indirect measurements
GISOLFI, C. V., Summers, R. W., Schedl, H. P., BLEILER, T. L., & Oppliger, R. A. (1990) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1990.258.2.g216 · Cited by 71 · see citing works
CHO Oxidation from a CHO Gel Compared with a Drink during Exercise
Pfeiffer, B., Stellingwerff, T., Zaltas, E., & Jeukendrup, A. E. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181e0efe6 · Cited by 69 · see citing works
Self-citationExogenous Oxidation of Isomaltulose Is Lower than That of Sucrose during Exercise in Men
Achten, J., Jentjens, R. L., Brouns, F., & Jeukendrup, A. E. (2007) · The Journal of Nutrition · doi:10.1093/jn/137.5.1143 · Cited by 67 · see citing works
Self-citationOxidation of exogenous [13C]galactose and [13C]glucose during exercise
van Aggel‐Leijssen, D. P., Saris, W. H. M., Jeukendrup, A. E., & Wagenmakers, A. J. M. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.79.3.720 · Cited by 63 · see citing works
Self-citationUpper limit for intestinal absorption of a dilute glucose solution in men at rest
Duchman, S. M., Ryan, A. J., Schedl, H. P., Summers, R. W., BLEILER, T. L., & GISOLFI, C. V. (1997) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199704000-00009 · Cited by 59 · see citing works
Nutritional manipulations before and during endurance exercise
Coggan, A. R., & Swanson, S. C. (1992) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199209001-00005 · Cited by 58 · see citing works
Exogenous CHO Oxidation with Glucose Plus Fructose Intake during Exercise
Hulston, C. J., Wallis, G. A., & Jeukendrup, A. E. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181857ee6 · Cited by 54 · see citing works
Self-citationBurelle, Y., Lamoureux, M.-C., Pèronnet, F., Massicotte, D., & Lavoie, C. (2006) · British Journal of Nutrition · doi:10.1079/bjn20061799 · Cited by 51 · see citing works
Glucose ingestion during endurance training does not alter adaptation
Akerstrom, T. C. A., Fischer, C. P., Plomgaard, P., Thomsen, C., van Hall, G., & Pedersen, B. K. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91534.2008 · Cited by 33 · see citing works
Glucose Polymer Molecular Weight Does Not Affect Exogenous Carbohydrate Oxidation
ROWLANDS, D. S., WALLIS, G. A., SHAW, C., JENTJENS, R. L. P. G., & JEUKENDRUP, A. E. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000177586.68399.f5 · Cited by 32 · see citing works
Self-citationPlasma deuterium oxide accumulation following ingestion of different carbohydrate beverages
Currell, K., Urch, J., Cerri, E., Jentjens, R. L. P. G., Blannin, A. K., & Jeukendrup, A. E. (2008) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h08-084 · Cited by 31 · see citing works
Self-citationCarbohydrate Oxidation from a Drink during Running Compared with Cycling Exercise
Pfeiffer, B., Stellingwerff, T., Zaltas, E., Hodgson, A. B., & Jeukendrup, A. E. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181ebc488 · Cited by 31 · see citing works
Self-citationOxidation of Maltose and Trehalose during Prolonged Moderate-Intensity Exercise
VENABLES, M. C., BROUNS, F., & JEUKENDRUP, A. E. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318175716c · Cited by 27 · see citing works
Self-citationThe effect of galactose supplementation on endurance cycling performance
Stannard, S. R., Hawke, E. J., & Schnell, N. (2009) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602924 · Cited by 22 · see citing works
Evidence of a Carbohydrate Dose and Prolonged Exercise Performance Relationship
Smith, J. W., Zachwieja, J. J., Horswill, C. A., Pascoe, D. D., Passe, D. H., Ruby, B. C., & Stewart, L. K. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000385615.40977.c3 · Cited by 18 · see citing works
Legal Nutritional Boosting for Cycling
Jeukendrup, A. E., & Tipton, K. D. (2009) · Current Sports Medicine Reports · doi:10.1249/jsr.0b013e3181ae9950 · Cited by 13 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
A Step Towards Personalized Sports Nutrition: Carbohydrate Intake During Exercise
Jeukendrup, A. (2014) · Sports Medicine · doi:10.1007/s40279-014-0148-z · Cited by 412 · see citing works
Self-citationGastrointestinal Complaints During Exercise: Prevalence, Etiology, and Nutritional Recommendations
de Oliveira, E. P., Burini, R. C., & Jeukendrup, A. (2014) · Sports Medicine · doi:10.1007/s40279-014-0153-2 · Cited by 402 · see citing works
Self-citationPeriodized Nutrition for Athletes
Jeukendrup, A. E. (2017) · Sports Medicine · doi:10.1007/s40279-017-0694-2 · Cited by 299 · see citing works
Self-citationJeukendrup, A. E. (2017) · Sports Medicine · doi:10.1007/s40279-017-0690-6 · Cited by 208 · see citing works
Self-citationCosta, R. J. S., Miall, A., Khoo, A., Rauch, C., Snipe, R., Camões-Costa, V., & Gibson, P. (2017) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0453 · Cited by 162 · see citing works
Costa, R. J. S., Gill, S. K., Hankey, J., Wright, A., & Marczak, S. (2014) · British Journal of Nutrition · doi:10.1017/s0007114514000907 · Cited by 99 · see citing works
The New Carbohydrate Intake Recommendations
Jeukendrup, A. (2013) · Nestlé Nutrition Institute Workshop Series · doi:10.1159/000345820 · Cited by 23 · see citing works
Self-citation
- Authors
- Jeukendrup, A. E., & McLaughlin, J.
- Affiliations
- University of Birmingham (GB)
- University of Manchester (GB)
- ORCID
- McLaughlin, John
- Venue
- Nestlé Nutrition Institute Workshop Series
- Publisher
- S. Karger AG
- Published
- 2011
- Volume
- 69
- Pages
- 1-18
- ISSN
- 1664-2147 (ISSN-L)
- 1664-2155
- OpenAlex
- W2136364432
- Cited by
- 46
- References
- 57
- Citations by year
- 2024: 2 · 2023: 4 · 2022: 2 · 2021: 4 · 2020: 2 · 2018: 6 · 2017: 5 · 2016: 8 · 2015: 2 · 2014: 5 · 2013: 5 · 2012: 1
- FWCI
- 42.66
- Type
- conference paper
- Language
- en
- Open access
- closed
- Locations
- Nestlé Nutrition Institute Workshop series (publishedVersion)
- PubMed (publishedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Funders
- Biotechnology and Biological Sciences Research Council (BB/G005591/1)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- endurance performance, exogenous carbohydrate oxidation, training effects
- MeSH terms
- Adaptation, Physiological, Dietary Carbohydrates, Eating, Humans, Intestinal Absorption, Intestinal Mucosa, Oxidation-Reduction, Physical Endurance, Exercise, Muscle, Skeletal, Carbohydrate Metabolism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review