The DOI matches its Crossref record; 209 of the 209 references it cites were found in a registry or an index.
Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms
Open accessAbstract
The alternatively activated or M2 macrophages are immune cells with high phenotypic heterogeneity and are governing functions at the interface of immunity, tissue homeostasis, metabolism, and endocrine signaling. Today the M2 macrophages are identified based on the expression pattern of a set of M2 markers. These markers are transmembrane glycoproteins, scavenger receptors, enzymes, growth factors, hormones, cytokines, and cytokine receptors with diverse and often yet unexplored functions. This review discusses whether these M2 markers can be reliably used to identify M2 macrophages and define their functional subdivisions. Also, it provides an update on the novel signals of the tissue environment and the neuroendocrine system which shape the M2 activation. The possible evolutionary roots of the M2 macrophage functions are also discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In turn, the appearance of anti-inflammatory cytokines, such as IL-10, IL-4 or IL-13, promotes the M2 phenotype, which is coordinated by the STAT-6 transcription factor [192,193,194].”
From MicroRNAs as Regulators of Phagocytosis (2022) · cites this paper as [193]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function
Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481
Macrophage activation and polarization: nomenclature and experimental guidelines
Murray, P. J., Allen, J. E., Biswas, S. K., Fisher, E. A., Gilroy, D. W., Goerdt, S., Gordon, S., Hamilton, J. A., Ivashkiv, L. B., Lawrence, T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.06.008 · Cited by 6,337
Macrophage plasticity and polarization: in vivo veritas
Sica, A., & Mantovani, A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci59643 · Cited by 6,335
MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528
The M1 and M2 paradigm of macrophage activation: Time for reassessment
Martinez, F. O., & Gordon, S. (2014) · F1000Prime Reports · doi:10.12703/p6-13 · Cited by 4,689
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578
What we talk about when we talk about fat
Rosen, E. D., & Spiegelman, B. M. (2014) · Cell · doi:10.1016/j.cell.2013.12.012 · Cited by 2,373
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
Gomez Perdiguero, E., Klapproth, K., Schulz, C., Busch, K., Azzoni, E., Crozet, L., Garner, H., Trouillet, C., de Bruijn, M. F., Geissmann, F., et al. (2015) · Nature · doi:10.1038/nature13989 · Cited by 2,339 · cited 1×
“However, it is shown that the resident tissue macrophages have heterogeneous progeny [187, 188].”
BackgroundThe cellular and signaling networks linking the immune system and metabolism in disease
Osborn, O., & Olefsky, J. M. (2012) · Nature Medicine · doi:10.1038/nm.2627 · Cited by 1,551
Epelman, S., Lavine, K. J., Beaudin, A. E., Sojka, D. K., Carrero, J. A., Calderon, B., Brija, T., Gautier, E. L., Ivanov, S., Satpathy, A. T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2013.11.019 · Cited by 1,494
Flagged first, then by citations
Research works printed but not linked: 1
- 10.1189/jlb.4AB0813-434R · DOI
Cited by
Sorted by citations
Items 701–800 of 1,002
Immunomodulatory effects of metal nanoparticles: current trends and future prospects
Barik, P., & Mondal, S. (2025) · Nanoscale · doi:10.1039/d5nr01030f · Cited by 28
CD206 + IL-4Rα + Macrophages Are Drivers of Adverse Cardiac Remodeling in Ischemic Cardiomyopathy
Wang, Q., Ismahil, M. A., Zhu, Y., Rokosh, G. D., Hamid, T., Zhou, G., Pogwizd, S. M., & Prabhu, S. D. (2025) · Circulation · doi:10.1161/circulationaha.124.072411 · Cited by 30
Cao, L., Ding, L., Xia, Q., Zhang, Z., Li, M., Song, S., Yin, K., Li, Z., Li, X., Wang, Z., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07075-0 · Cited by 30
Ethanol intoxication prolongs post-burn pulmonary inflammation: role of alveolar macrophages
Shults, J. A., Curtis, B. J., Boe, D. M., Ramírez, L., & Kovacs, E. J. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.3ma0316-111r · Cited by 24
Ovsiy, I., Riabov, V., Manousaridis, I., Michel, J., Moganti, K., Yin, S., Liu, T., Sticht, C., Kremmer, E., Harmsen, M. C., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-17307-z · Cited by 23
Axl Involved in Mineral Trioxide Aggregate Induces Macrophage Polarization
Yeh, H.-W., Chiang, C., Chen, P.-H., Su, C.-C., Wu, Y., Chou, L., Huang, R., Liu, S.-Y., & Shieh, Y. (2018) · Journal of Endodontics · doi:10.1016/j.joen.2018.07.005 · Cited by 24
Lutshumba, J., Ochiai, E., Sa, Q., Anand, N., & Suzuki, Y. (2020) · mSystems · doi:10.1128/msystems.00189-20 · Cited by 24
Lourenssen, S. R., & Blennerhassett, M. G. (2020) · American Journal Of Pathology · doi:10.1016/j.ajpath.2020.05.015 · Cited by 24
Kaur, G., Wright, K., Mital, P., Hibler, T., Miranda, J. M., Thompson, L. A., Halley, K., & Dufour, J. M. (2020) · Cell Transplantation · doi:10.1177/0963689720947102 · Cited by 24
The Mononuclear Phagocyte System of the Rat
Hume, D. A., Caruso, M., Keshvari, S., Patkar, O. L., Sehgal, A., Bush, S. J., SUMMERS, K. M., Pridans, C., & Irvine, K. M. (2021) · The Journal of Immunology · doi:10.4049/jimmunol.2100136 · Cited by 22
A Signaling View into the Inflammatory Tumor Microenvironment
Pereira, J., Jordan, P., & Matos, P. (2021) · Immuno · doi:10.3390/immuno1020007 · Cited by 24
Nordlohne, J., Hulsmann, I., Schwafertz, S., Zgrajek, J., Grundmann, M., von Vietinghoff, S., Eitner, F., & Becker, M. S. (2021) · Scientific Reports · doi:10.1038/s41598-021-92784-x · Cited by 24
Hobby, A. R. H., Berretta, R. M., Eaton, D., Kubo, H., Feldsott, E. A., Yang, Y., Headrick, A. L., Koch, K. A., Rubino, M., Kurian, J. J., et al. (2021) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00304.2021 · Cited by 24
Song, Y., Liao, M., Zhao, X. H., Han, H., Dong, X., Wang, X., Du, M., & Yan, H. (2021) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.62.12.26 · Cited by 24
Evaluation of immunotherapies improving macrophage anti-tumor response using a microfluidic model
Chernyavska, M., Hermans, C. K. J. C., Chan, C., Baumann, N., Rösner, T., Leusen, J. H. W., Valerius, T., & Verdurmen, W. P. R. (2022) · Organs-on-a-Chip · doi:10.1016/j.ooc.2022.100019 · Cited by 25
Holthaus, M., Santhakumar, N., Wahlers, T., & Paunel‐Görgülü, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084104 · Cited by 25
Broeckhoven, J. V., Erens, C., Sommer, D., Scheijen, E. E. M., Sanchez, S., Vidal, P. M., Dooley, D., Breedam, E. V., Quarta, A., Ponsaerts, P., et al. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02458-2 · Cited by 23
Khoza, L. J., Kumar, P., Dube, A., Demana, P. H., & Choonara, Y. E. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121893 · Cited by 24
Applications of functionally-adapted hydrogels in tendon repair
Hu, J., Liu, S., & Fan, C. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1135090 · Cited by 26
Li, Y., Ma, Y., Yu, J., Li, C., Yu, D., Dai, R., Li, Q., & Cao, C. Y. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124920 · Cited by 24
Differential response to intrahippocampal interleukin-4/interleukin-13 in aged and exercise mice
Littlefield, A. M., & Kohman, R. A. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.11.027 · Cited by 24
S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1βor Lipocalin-2
Syed, S. N., Jung, M., Weigert, A., & Brüne, B. (2017) · Mediators of Inflammation · doi:10.1155/2017/7510496 · Cited by 24
Lai, C., Stepniak, D. T., Sias, L., & Funatake, C. J. (2017) · Methods · doi:10.1016/j.ymeth.2017.12.016 · Cited by 24
Colson, C., Ghandour, R. A., Dufies, O., Rekima, S., Loubat, A., Munro, P. M., Boyer, L., & Pisani, D. F. (2019) · Nutrients · doi:10.3390/nu11020438 · Cited by 27
Understanding the Metabolic Profile of Macrophages During the Regenerative Process in Zebrafish
Paredes, L. C., Câmara, N. O. S., & Braga, T. T. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00617 · Cited by 23
Advances in studies on tracheal stent design addressing the related complications
Chen, S., Du, T., Zhang, H., Zhang, Y., & Qiao, A. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101263 · Cited by 23
Reprogramming cellular senescence and aging clocks for advanced cancer immunotherapy
Yang, H., Liu, D., Qiu, L., Wang, R., Zhang, C., Yu, D., Zhong, Q., Yuki, N., Song, Z., Zhu, Τ., et al. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02459-8 · Cited by 30
Koeniger, T., & Küerten, S. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18102072 · Cited by 22
Over-expression of IQGAP1 indicates poor prognosis in head and neck squamous cell carcinoma
Wu, C., Li, H., Xiao, Y., Yang, L., Chen, L., Deng, W., Wu, L., Zhang, W., & Sun, Z. (2018) · Journal of Molecular Histology · doi:10.1007/s10735-018-9779-y · Cited by 23
Hussein, K., Stucki‐Koch, A., Müller, A. M., Arnold, R., Kreipe, H. H., & Feist, H. (2019) · Placenta · doi:10.1016/j.placenta.2019.02.007 · Cited by 23
Lu, Y., Guo, L., & Ding, G. (2019) · Future Oncology · doi:10.2217/fon-2019-0519 · Cited by 23
How Macrophages Become Transcriptionally Dysregulated: A Hidden Impact of Antitumor Therapy
Medvedeva, G. F., Kuzmina, D. O., Nuzhina, J., Shtil, A. A., & Dukhinova, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052662 · Cited by 24
Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1
Ma, D., Zhan, D., Fu, Y., Wei, S., Lal, B., Wang, J., Li, Y.-Q., López-Bertoni, H., Yalçın, F., Dzaye, O. D. A., et al. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.05.038 · Cited by 23
Mansour, S. M., Shamma, R. N., Ahmed, K. A., Sabry, N. A., Esmat, G., Mahmoud, A. A. K., & Maged, A. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.108004 · Cited by 23
Biological Mechanisms and Therapeutic Opportunities in Mammographic Density and Breast Cancer Risk
Archer, M., Dasari, P., Evdokiou, A., & Ingman, W. V. (2021) · Cancers · doi:10.3390/cancers13215391 · Cited by 23
Neuroinflammatory Modulation of Extracellular Vesicle Biogenesis and Cargo Loading
Spiers, J. G., Vassileff, N., & Hill, A. F. (2022) · NeuroMolecular Medicine · doi:10.1007/s12017-022-08704-3 · Cited by 22
Magnetic resonance imaging of tumor-associated-macrophages (TAMs) with a nanoparticle contrast agent
Zhou, J., Meli, V. S., Chen, E. Y., Kapre, R., Nagalla, R. R., Xiao, W., Borowsky, A. D., Lam, K. S., Liu, W. F., & Louie, A. Y. (2022) · RSC Advances · doi:10.1039/d1ra08061j · Cited by 24
Immunoregulation of synovial macrophages for the treatment of osteoarthritis
Xu, M., & Ji, Y. (2023) · Open Life Sciences · doi:10.1515/biol-2022-0567 · Cited by 23
Chen, Z., Xing, F., Zhou, Y., Yu, P., Xu, J., Luo, R., Zhou, C., Xiang, Z., Rommens, P. M., Liu, M., et al. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb00727h · Cited by 25
Hirabayashi, K., Tanaka, M., Imai, A., Toriyama, Y., Iesato, Y., Sakurai, T., Kamiyoshi, A., Ichikawa‐Shindo, Y., Kawate, H., Tanaka, M., et al. (2019) · American Journal Of Pathology · doi:10.1016/j.ajpath.2018.10.021 · Cited by 23
Menarim, B. C., Gillis, K. H., Oliver, A., Mason, C., Ngo, Y., Werre, S. R., Barrett, S. H., Luo, X., Byron, C. R., & Dahlgren, L. A. (2019) · The FASEB Journal · doi:10.1096/fj.201901684rr · Cited by 24
Maguire, G. (2019) · PubMed Central · Cited by 22
Vasamsetti, S. B., Coppin, E., Zhang, X., Florentin, J., Koul, S. M., Götberg, M., Clugston, A. S., Thoma, F. W., Sembrat, J., Bullock, G. C., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aaw0638 · Cited by 23
Matusiak, M., Hickey, J. W., Luca, B. A., Lu, G., Kidziński, Ł., Zhu, S., Colburg, D. R. C., Phillips, D. J., Brubaker, S. W., Charville, G. W., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2393443/v1 · Cited by 23
Jeong, S., Kim, M., Baek, S., Lee, J.-W., Lee, H., Cao, B., Kim, Y., Cao, L., & Lee, S. G. (2023) · Marine Drugs · doi:10.3390/md21100533 · Cited by 22
Tumor‐Associated Macrophages: Key Players in the Non‐Small Cell Lung Cancer Tumor Microenvironment
Lv, T., Fan, R., Wu, J., Gong, H., Gao, X., Liu, X., Gong, Y., Luo, B., Zhang, Y., Peng, X., et al. (2025) · Cancer Medicine · doi:10.1002/cam4.70670 · Cited by 25
Mechanisms and Therapeutic Strategies of Macrophage Polarization in Intervertebral Disc Degeneration
Zheng, K., Wang, S., Deng, M., Luo, Y., Li, W., Zeng, L., & Wang, Y. (2025) · JOR Spine · doi:10.1002/jsp2.70065 · Cited by 24
Myricetin alleviates DNCB-induced atopic dermatitis by modulating macrophage M1/M2 polarization
Zhang, X., Li, J., Liu, Y., Ma, R., Li, C., Xu, Z., Wang, R., Zhang, L., & Zhang, Y. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115212 · Cited by 22
Thankam, F. G., Dilisio, M. F., Dougherty, K. A., Dietz, N. E., & Agrawal, D. K. (2016) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2016.1196138 · Cited by 22
Immune Dysregulation in HFpEF: A Target for Mesenchymal Stem/Stromal Cell Therapy
Sava, R., Pepine, C. J., & March, K. L. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9010241 · Cited by 22
Penkert, R. R., Smith, A. P., Hrincius, E. R., McCullers, J. A., Vogel, P., Smith, A. M., & Hurwitz, J. L. (2020) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa597 · Cited by 23
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M
Botelho, F. M., Dubey, A., Ayaub, E. A., Park, R., Yip, A., Humbles, A. A., Kolbeck, R., & Richards, C. D. (2020) · Mediators of Inflammation · doi:10.1155/2020/4087315 · Cited by 21
Bioactivation of Encapsulation Membranes Reduces Fibrosis and Enhances Cell Survival
Tan, R. P., Hallahan, N., Kosobrodova, E., Michael, P. L., Wei, F., Santos, M., Lam, Y. T., Chan, A., Xiao, Y., Bilek, M., et al. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c20096 · Cited by 22
Cross Talk Between Macrophages and Cancer Cells in the Bone Metastatic Environment
Batoon, L., & McCauley, L. K. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.763846 · Cited by 22
Liang, Z., Yu, J., Gu, D., Liu, X., Liu, J., Wu, M., Xu, M., Shen, M., Duan, W., & Li, W. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17191 · Cited by 21
Dai, M., Yang, X., Yu, Y., & Pan, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.827486 · Cited by 23
Varasteh, Z., Braeuer, M., Mohanta, S. K., Steinsiek, A.-L., Habenicht, A. J. R., Omidvari, N., Topping, G. J., Rischpler, C., Weber, W., Sager, H. B., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.889963 · Cited by 22
Rahmannia, M., Amini, A., Chien, S., & Bayat, M. (2022) · Lasers in Medical Science · doi:10.1007/s10103-022-03581-5 · Cited by 22
Formyl peptide receptor 2 as a potential therapeutic target for inflammatory bowel disease
Yang, W., Wang, J., Wu, W., Wang, G., Yan, J., Liu, Q., Wu, X., Zhou, Q., Yang, D., Wang, M., et al. (2022) · Acta Pharmacologica Sinica · doi:10.1038/s41401-022-00944-0 · Cited by 22
Tissue-adhesive hydrogel for multimodal drug release to immune cells in skin
Day, N. B., Dalhuisen, R., Loomis, N. E., Adzema, S. G., Prakash, J., & Shields, C. W. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.07.053 · Cited by 22
Brain-targeted antigen-generating nanoparticles improve glioblastoma prognosis
Wang, W., Zhang, M., Zhang, Q., Mohammadniaei, M., Shen, J., & Sun, Y. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.10.037 · Cited by 22
Asveda, T., Talwar, P., & Ravanan, P. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121920 · Cited by 23
Zhu, J., Fan, J., Xia, Y., Wang, H., Li, Y., Feng, Z., & Fu, C. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1219487 · Cited by 26
The role of tumor‐associated macrophages in hepatocellular carcinoma progression: A narrative review
Zhang, X., Yu, C., Zhao, S., Wang, M., Shang, L., Zhou, J., & Ma, Y. (2023) · Cancer Medicine · doi:10.1002/cam4.6717 · Cited by 24
Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus
Kozareva, D. A., Hueston, C. M., Ó’Léime, C. S., Crotty, S., Dockery, P., Cryan, J. F., & Nolan, Y. M. (2017) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2017.08.008 · Cited by 22
Living in a Hostile World: Inflammation, New Drug Development, and Coronavirus
Dobson, G. P., Biroš, E., Letson, H. L., & Morris, J. L. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.610131 · Cited by 22
The impact of helminth-induced immunity on infection with bacteria or viruses
Chen, H., Cao, Z., Liu, M., Diamond, M., & Jin, X. (2023) · Veterinary Research · doi:10.1186/s13567-023-01216-3 · Cited by 21
Chest wall reconstruction, prosthesis and allografts: a narrative review
Girotti, P. N. C., & Bianchi, F. (2023) · Journal of Thoracic Disease · doi:10.21037/jtd-23-650 · Cited by 21
Sullivan, K. M., Li, H., Yang, A., Zhang, Z., Muñoz, R. M., Mahuron, K. M., Yuan, Y., Paz, I. B., Hoff, D. D. V., Han, H., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25074117 · Cited by 22
S100A8/9 modulates perturbation and glycolysis of macrophages in allergic asthma mice
Ji, X., Nie, C., Yao, Y., Ma, Y., Huang, H., & Hao, C. (2024) · PeerJ · doi:10.7717/peerj.17106 · Cited by 21
Meng, Y., Li, M., Peng, D., Wang, Y., Li, S., Zhang, D., Yang, B. K., Qiu, H., & Li, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212078 · Cited by 21
Zhao, F., Yue, Z., Zhang, L., Qi, Y., Sun, Y., Wang, S., & Tian, Q. (2025) · Journal of Innate Immunity · doi:10.1159/000546476 · Cited by 23
Macrophage polarization in vitro and in vivo modified by contact with fragmented chitosan hydrogel
von Boxberg, Y., Soares, S., Giraudon, C., David, L., Viallon, M., Montembault, A., & Nothias, F. (2021) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37326 · Cited by 23
Tumor‐Associated Macrophages in Vestibular Schwannoma and Relationship to Hearing
Nisenbaum, E., Misztal, C., Szczupak, M., Thielhelm, T., Peña, S., Mei, C., Goncalves, S., Bracho, O., Ma, R., Ivan, M. E., et al. (2021) · OTO Open · doi:10.1177/2473974x211059111 · Cited by 21
Mukai, K., Horike, S., Meguro‐Horike, M., Nakajima, Y., Iswara, A., & Nakatani, T. (2022) · PLoS ONE · doi:10.1371/journal.pone.0264572 · Cited by 22
Hsieh, L., Lu, M.-S., & Chiang, W. (2022) · Bioresources and Bioprocessing · doi:10.1186/s40643-022-00526-2 · Cited by 21
Vitamin D, Th17 Lymphocytes, and Breast Cancer
Filip‐Psurska, B., Zachary, H., Strzykalska-Augustyniak, A., & Wietrzyk, J. (2022) · Cancers · doi:10.3390/cancers14153649 · Cited by 21
Tariq, M., Hussain, N., Rehman, K., Akash, M. S. H., Haddad, A. H. I. A., Said, A. S. A., Fatease, A. M. A., Alamri, A., Safhi, A. Y., Sabei, F. Y., et al. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114527 · Cited by 21
Engineered macrophages acting as a trigger to induce inflammation only in tumor tissues
Tanito, K., Nii, T., Yokoyama, Y., Oishi, H., Shibata, M., Hijii, S., Kaneko, R., Tateishi, C., Ito, S., Kishimura, A., et al. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.04.010 · Cited by 21
Zeng, Y.-X., Chou, K.-Y., Hwang, J., & Wang, H.-S. (2023) · Scientific Reports · doi:10.1038/s41598-023-37741-6 · Cited by 21
Raimo, T. D., Leopizzi, M., Mangino, G., Rocca, C. D., Businaro, R., Longo, L., & Vasco, V. R. L. (2016) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-016-0335-9 · Cited by 21
Ando, Y., Oku, T., & Tsuji, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162208 · Cited by 22
New perspectives on the regulation of type II inflammation in asthma
Becerra-Díaz, M. (2017) · F1000Research · doi:10.12688/f1000research.11198.1 · Cited by 21
Mulder, R., Banete, A., Seaver, K., & Basta, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01629 · Cited by 21
Proinflammatory polarization of stifle synovial macrophages in dogs with cruciate ligament rupture
Yarnall, B. W., Chamberlain, C. S., Hao, Z., & Muir, P. (2019) · Veterinary Surgery · doi:10.1111/vsu.13261 · Cited by 23
Ding, X., Zhang, J., Shi, M., Liu, D., Zhang, L., Zhang, R., Su, B., & Ai, K. (2020) · Clinical & Translational Oncology · doi:10.1007/s12094-020-02392-w · Cited by 21
Swartzwelter, B. J., Verde, A., Rehak, L., Madej, M. P., Puntes, V., Luca, A. C. D., Boraschi, D., & Italiani, P. (2021) · Nanomaterials · doi:10.3390/nano11010207 · Cited by 21
Targeting Certain Interleukins as Novel Treatment Options for Liver Fibrosis
An, S. Y., Petrescu, A. D., & DeMorrow, S. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.645703 · Cited by 21
Franzoni, G., Bonelli, P., Graham, S. P., Anfossi, A. G., Giudici, S. D., Pilo, G., Pittau, M., Nicolussi, P., & Oggiano, A. (2017) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2017.04.006 · Cited by 21
Désert, R., Giannone, F., Saviano, A., Hoshida, Y., Heikenwälder, M. F., Nahon, P., & Baumert, T. F. (2025) · npj gut and liver. · doi:10.1038/s44355-025-00018-y · Cited by 23
Jiang, Y., Zhang, L., Lin, Y., Zhu, X., Wang, T., Zhu, Z., Chen, Y., & Tang, D. (2025) · Molecules and Cells · doi:10.1016/j.mocell.2025.100264 · Cited by 23
Wang, Y., Mao, J., Wang, Y., Wang, R., Duan, D., Liu, Z., Hu, X., Yu, Z., & Shi, X. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.11.057 · Cited by 24
Chang, S., Tu, H., Lai, Y. C., Luo, C., Nejo, T., Tanaka, S., Chai, C., & Kwan, A. (2020) · Diagnostics · doi:10.3390/diagnostics10050256 · Cited by 20
Hypoperfusion is a potential inducer of immunosuppressive network in Alzheimer's disease
Salminen, A. (2020) · Neurochemistry International · doi:10.1016/j.neuint.2020.104919 · Cited by 20
Characterization of tumor‐associated macrophages in prostate cancer transgenic mouse models
de Groot, A. E., Myers, K. V., Krueger, T. E. G., Kiemen, A. L., Nagy, N. H., Brame, A., Torres, V. E., Zhang, Z., Trabzonlu, L., Brennen, W. N., et al. (2021) · The Prostate · doi:10.1002/pros.24139 · Cited by 20
Feng, D., Huang, W., Niu, X., Sheng, H., Zhang, L., & Hu, Y. (2021) · Rheumatology and Therapy · doi:10.1007/s40744-021-00385-x · Cited by 21
The Role of Innate Immune Cells in Tumor Invasion and Metastasis
Huang, Y., Busuttil, R. A., & Boussioutas, A. (2021) · Cancers · doi:10.3390/cancers13235885 · Cited by 22
Saranyutanon, S., Acharya, S., Deshmukh, S. K., Khan, M. A., Singh, S., & Singh, A. P. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30607 · Cited by 20
Ahn, W., Chi, G., Kim, S., Son, Y., & Zhang, M. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01284-7 · Cited by 20
Macrophage response mediated by extracellular matrix: recent progress
Xiao, W., Yang, Y., Chu, C., Rung, S., Wang, Z., Man, Y., Lin, J., & Qu, Y. (2022) · Biomedical Materials · doi:10.1088/1748-605x/aca946 · Cited by 21
Metadata
- Authors
- Rőszer, T.
- Affiliations
- Universität Ulm (DE)
- Corresponding author
- Rőszer, Tamás
- ORCID
- Rőszer, Tamás
- Venue
- Mediators of Inflammation
- Publisher
- Wiley
- Published
- 2015-01
- Volume
- 2015
- Issue
- 1
- Pages
- 816460-816460
- ISSN
- 0962-9351 (ISSN-L)
- 1466-1861
- PMC
- PMC4452191
- OpenAlex
- W1518095394
- Cited by
- 1,762
- References
- 209
- Citations by year
- 2026: 105 · 2025: 169 · 2024: 198 · 2023: 189 · 2022: 214 · 2021: 215 · 2020: 203 · 2019: 150 · 2018: 143 · 2017: 109 · 2016: 58 · 2015: 9
- FWCI
- 10.01
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Mediators of Inflammation (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Universität Ulm
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Keywords
- M2 macrophages, scavenger receptors, tissue microenvironment, tissue homeostasis, hormone signaling
- MeSH terms
- Humans, Macrophage Activation, Macrophages, Neurosecretory Systems
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review