Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy
Selenica, Maj-Linda B., Brownlow, Milene, Jimenez, Jeffy P., Lee, Daniel C., Pena, Gabriela, Dickey, Chad A., Gordon, Marcia N., Morgan, Dave·2013·Neurodegenerative Diseases
Cited by (1,606)
Items 101–200 of 1,606
- Defining imaging biomarker cut points for brain aging and Alzheimer's diseaseJack, Clifford R., Wiste, Heather J., Weigand, Stephen D., Therneau, Terry M., Lowe, Val J., Knopman, David S., Gunter, Jeffrey L., Senjem, Matthew L., Jones, David T., Kantarci, Kejal et al. · 2017 · Alzheimer's & Dementia
- Inflammation and immunity in schizophrenia: implications for pathophysiology and treatmentKhandaker, Golam M, Cousins, Lesley, Deakin, Julia, Lennox, Belinda R, Yolken, Robert, Jones, Peter B · 2015 · The Lancet Psychiatry
- TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's diseaseAmador‐Ortiz, Catalina, Lin, Wen‐Lang, Ahmed, Zeshan, Personett, David, Davies, Peter, Duara, Ranjan, Graff‐Radford, Neill R., Hutton, Michael L., Dickson, Dennis W. · 2007 · Annals of Neurology
- Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer’s diseaseMahley, Robert W., Weisgraber, Karl H., Huang, Yadong · 2006 · Proceedings of the National Academy of Sciences
- Microglia in Alzheimer's diseaseSarlus, Heela, Heneka, Michael T. · 2017 · Journal of Clinical Investigation
- A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of NanotherapeuticsRichard Nii Lante Lamptey, Bivek Chaulagain, Riddhi Trivedi, Avinash Gothwal, Buddhadev Layek, Jagdish Singh · 2022 · International Journal of Molecular Sciences
- Increased hippocampal activation in mild cognitive impairment compared to normal aging and ADDickerson, B. C., Salat, D. H., Greve, D. N., Chua, E. F., Rand-Giovannetti, E., Rentz, D. M., Bertram, L., Mullin, K., Tanzi, R. E., Blacker, D. et al. · 2005 · Neurology
- Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic miceJosé J. Lucas, Félix Hernández, Pilar Gómez‐Ramos, María A. Morán, René Hen, Jesús Avila · 2001 · The EMBO Journal
- Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiotaHarach, T., Marungruang, N., Duthilleul, N., Cheatham, V., Mc Coy, K. D., Frisoni, G., Neher, J. J., Fåk, F., Jucker, M., Lasser, T. et al. · 2017 · Scientific Reports
- Brain glucose metabolism in the early and specific diagnosis of Alzheimer?s diseaseLisa Mosconi · 2005 · European Journal of Nuclear Medicine and Molecular Imaging
- Degradation of misfolded proteins in neurodegenerative diseases: Therapeutic targets and strategiesCiechanover, Aaron, Kwon, Yong Tae · 2015 · Experimental & Molecular Medicine
- Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and TauCaccamo, Antonella, Majumder, Smita, Richardson, Arlan, Strong, Randy, Oddo, Salvatore · 2010 · Journal of Biological Chemistry
- Structure-based classification of tauopathiesShi, Yang, Zhang, Wenjuan, Yang, Yang, Murzin, Alexey G., Falcon, Benjamin, Kotecha, Abhay, van Beers, Mike, Tarutani, Airi, Kametani, Fuyuki, Garringer, Holly J. et al. · 2021 · Nature
- Heterogeneity of Microglial Activation in the Innate Immune Response in the BrainCarol A. Colton · 2009 · Journal of Neuroimmune Pharmacology
- Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degenerationJin, Ming, Shepardson, Nina, Yang, Ting, Chen, Gang, Walsh, Dominic, Selkoe, Dennis J. · 2011 · Proceedings of the National Academy of Sciences
- ApoE Promotes the Proteolytic Degradation of AβJiang, Qingguang, Lee, C.Y. Daniel, Mandrekar, Shweta, Wilkinson, Brandy, Cramer, Paige, Zelcer, Noam, Mann, Karen, Lamb, Bruce, Willson, Timothy M., Collins, Jon L. et al. · 2008 · Neuron
- The Amyloid-β Oligomer Hypothesis: Beginning of the Third DecadeCline, Erika N., Bicca, Maíra Assunção, Viola, Kirsten L., Klein, William L. · 2018 · Journal of Alzheimer's Disease
- Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrinZenaro, Elena, Pietronigro, Enrica, Bianca, Vittorina Della, Piacentino, Gennj, Marongiu, Laura, Budui, Simona, Turano, Ermanna, Rossi, Barbara, Angiari, Stefano, Dusi, Silvia et al. · 2015 · Nature Medicine
- The genetic landscape of Alzheimer disease: clinical implications and perspectivesVan Cauwenberghe, Caroline, Van Broeckhoven, Christine, Sleegers, Kristel · 2016 · Genetics in Medicine
- Microglial Phagocytosis of Live NeuronsBrown, Guy C., Neher, Jonas J. · 2014 · Nature Reviews Neuroscience
- Mitochondria and Mitochondrial Cascades in Alzheimer’s diseaseSwerdlow, Russell H. · 2018 · Journal of Alzheimer’s Disease
- Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's DiseaseKametani, Fuyuki, Hasegawa, Masato · 2018 · Frontiers in Neuroscience
- Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer’s diseaseGeorganopoulou, Dimitra G., Chang, Lei, Nam, Jwa-Min, Thaxton, C. Shad, Mufson, Elliott J., Klein, William L., Mirkin, Chad A. · 2005 · Proceedings of the National Academy of Sciences
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damageMaria Mańczak, Marcus J. Calkins, P. Hemachandra Reddy · 2011 · Human Molecular Genetics
- Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's diseaseGamblin, T. Chris, Chen, Feng, Zambrano, Angara, Abraha, Aida, Lagalwar, Sarita, Guillozet, Angela L., Lu, Meiling, Fu, Yifan, Garcia-Sierra, Francisco, LaPointe, Nichole et al. · 2003 · Proceedings of the National Academy of Sciences
- Neuronal activity enhances tau propagation and tau pathology in vivoWu, Jessica W, Hussaini, S Abid, Bastille, Isle M, Rodriguez, Gustavo A, Mrejeru, Ana, Rilett, Kelly, Sanders, David W, Cook, Casey, Fu, Hongjun, Boonen, Rick A C M et al. · 2016 · Nature Neuroscience
- Alzheimer's disease: experimental models and realityDrummond, Eleanor, Wisniewski, Thomas · 2017 · Acta Neuropathologica
- Tau and neurodegenerative disease: the story so farIqbal, Khalid, Liu, Fei, Gong, Cheng-Xin · 2016 · Nature Reviews Neurology
- Spreading of pathology in neurodegenerative diseases: a focus on human studiesBrettschneider, Johannes, Tredici, Kelly Del, Lee, Virginia M.-Y., Trojanowski, John Q. · 2015 · Nature Reviews Neuroscience
- Stress granules and neurodegenerationBenjamin L. Wolozin, Pavel V. Ivanov · 2019 · Nature reviews. Neuroscience
- The Alzheimer’s disease mitochondrial cascade hypothesis: progress and perspectivesSwerdlow, Russell H., Burns, Jeffrey M., Khan, Shaharyar M. · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- The Semantics of Microglia Activation: Neuroinflammation, Homeostasis, and StressWoodburn, Samuel C., Bollinger, Justin L., Wohleb, Eric S. · 2021 · Journal of Neuroinflammation
- Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein TauAmbadipudi, Susmitha, Biernat, Jacek, Riedel, Dietmar, Mandelkow, Eckhard, Zweckstetter, Markus · 2017 · Nature Communications
- Molecular mechanisms of protein aggregation from global fitting of kinetic modelsGeorg Meisl, Julius B. Kirkegaard, Paolo Arosio, Thomas C. T. Michaels, Michele Vendruscolo, Christopher Martin Dobson, Sara Snogerup Linse, Tuomas P. J. Knowles · 2016 · Nature Protocols
- Molecular mechanisms of neurodegeneration in Alzheimer's diseaseCrews, L., Masliah, E. · 2010 · Human Molecular Genetics
- apoE isoform–specific disruption of amyloid β peptide clearance from mouse brainDeane, Rashid, Sagare, Abhay, Hamm, Katie, Parisi, Margaret, Lane, Steven, Finn, Mary Beth, Holtzman, David M., Zlokovic, Berislav V. · 2008 · Journal of Clinical Investigation
- Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic NeurodegenerationCunningham, Colm, Wilcockson, David C., Campion, Suzanne, Lunnon, Katie, Perry, V. Hugh · 2005 · The Journal of Neuroscience
- The case for rejecting the amyloid cascade hypothesisHerrup, Karl · 2015 · Nature Neuroscience
- Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degenerationAdvancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) investigators, Thijssen, Elisabeth H., La Joie, Renaud, Wolf, Amy, Strom, Amelia, Wang, Ping, Iaccarino, Leonardo, Bourakova, Viktoriya, Cobigo, Yann, Heuer, Hilary et al. · 2020 · Nature Medicine
- Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stressStamer, K., Vogel, R., Thies, E., Mandelkow, E., Mandelkow, E.-M. · 2002 · The Journal of Cell Biology
- Abundant Tau Filaments and Nonapoptotic Neurodegeneration in Transgenic Mice Expressing Human P301S Tau ProteinBridget Allen, Esther Ingram, Masaki Takao, Michael J. Smith, Ross Jakes, Kanwar Virdee, Hirotaka Yoshida, Max Holzer, Molly Craxton, Piers C. Emson et al. · 2002 · Journal of Neuroscience
- The amyloid hypothesis in Alzheimer disease: new insights from new therapeuticsKarran, Eric, De Strooper, Bart · 2022 · Nature Reviews Drug Discovery
- Four distinct trajectories of tau deposition identified in Alzheimer’s diseasethe Alzheimer’s Disease Neuroimaging Initiative, Vogel, Jacob W., Young, Alexandra L., Oxtoby, Neil P., Smith, Ruben, Ossenkoppele, Rik, Strandberg, Olof T., La Joie, Renaud, Aksman, Leon M., Grothe, Michel J. et al. · 2021 · Nature Medicine
- The Role of Amyloid-β Oligomers in Toxicity, Propagation, and ImmunotherapySengupta, Urmi, Nilson, Ashley N., Kayed, Rakez · 2016 · EBioMedicine
- Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease.Alonso, A C, Zaidi, T, Grundke-Iqbal, I, Iqbal, K · 1994 · Proceedings of the National Academy of Sciences
- Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement ActivationLui, Hansen, Zhang, Jiasheng, Makinson, Stefanie R., Cahill, Michelle K., Kelley, Kevin W., Huang, Hsin-Yi, Shang, Yulei, Oldham, Michael C., Martens, Lauren Herl, Gao, Fuying et al. · 2016 · Cell
- Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associatedRobinson, John L, Lee, Edward B, Xie, Sharon X, Rennert, Lior, Suh, EunRan, Bredenberg, Colin, Caswell, Carrie, Van Deerlin, Vivianna M, Yan, Ning, Yousef, Ahmed et al. · 2018 · Brain
- The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention TrialsSperling, Reisa, Mormino, Elizabeth, Johnson, Keith · 2014 · Neuron
- History and progress of hypotheses and clinical trials for Alzheimer’s diseaseLiu, Pei-Pei, Xie, Yi, Meng, Xiao-Yan, Kang, Jian-Sheng · 2019 · Signal Transduction and Targeted Therapy
- Green tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic MiceRezai-Zadeh, Kavon, Shytle, Doug, Sun, Nan, Mori, Takashi, Hou, Huayan, Jeanniton, Deborah, Ehrhart, Jared, Townsend, Kirk, Zeng, Jin, Morgan, David et al. · 2005 · The Journal of Neuroscience
- Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration
<i>in vivo</i>Noble, Wendy, Planel, Emmanuel, Zehr, Cindy, Olm, Vicki, Meyerson, Jordana, Suleman, Farhana, Gaynor, Kate, Wang, Lili, LaFrancois, John, Feinstein, Boris et al. · 2005 · Proceedings of the National Academy of Sciences
- Glial‐Neuronal Interactions in Alzheimer's Disease: The Potential Role of a ‘Cytokine Cycle’ in Disease ProgressionW. Sue T. Griffin, Jin G. Sheng, M. Claire Royston, Steve Gentleman, J.E. McKenzie, David Ian Graham, G.W. Roberts, Robert Emil Mrak · 1998 · Brain Pathology
- Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory ResponseSara Bachiller, Itzia Jiménez-Ferrer, Agnes Paulus, Yiyi Yang, Maria Swanberg, Tomas Deierborg, Antonio Boza‐Serrano · 2018 · Frontiers in Cellular Neuroscience
- Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse modelCalon, Frédéric, Lim, Giselle P., Yang, Fusheng, Morihara, Takashi, Teter, Bruce, Ubeda, Oliver, Rostaing, Phillippe, Triller, Antoine, Salem, Norman, Ashe, Karen H. et al. · 2004 · Neuron
- Intraneuronal Alzheimer Aβ42 Accumulates in Multivesicular Bodies and Is Associated with Synaptic PathologyTakahashi, Reisuke H., Milner, Teresa A., Li, Feng, Nam, Ellen E., Edgar, Mark A., Yamaguchi, Haruyasu, Beal, M. Flint, Xu, Huaxi, Greengard, Paul, Gouras, Gunnar K. · 2002 · The American Journal of Pathology
- New insights into atypical Alzheimer's disease in the era of biomarkersGraff-Radford, Jonathan, Yong, Keir X X, Apostolova, Liana G, Bouwman, Femke H, Carrillo, Maria, Dickerson, Bradford C, Rabinovici, Gil D, Schott, Jonathan M, Jones, David T, Murray, Melissa E · 2021 · The Lancet Neurology
- Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective StrategiesGoran Šimić, Mirjana Babić Leko, Selina Wray, Charles R. Harrington, Ivana Delalle, Nataša Jovanov Milošević, Danira Bažadona, Luc Buée, Rohan de Silva, Giuseppe Di Giovanni et al. · 2016 · Biomolecules
- Multimodal techniques for diagnosis and prognosis of Alzheimer's diseasePerrin, Richard J., Fagan, Anne M., Holtzman, David M. · 2009 · Nature
- Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)Ramsden, Martin, Kotilinek, Linda, Forster, Colleen, Paulson, Jennifer, McGowan, Eileen, SantaCruz, Karen, Guimaraes, Aaron, Yue, Mei, Lewis, Jada, Carlson, George et al. · 2005 · The Journal of Neuroscience
- Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's diseaseJacobsen, J. Steven, Wu, Chi-Cheng, Redwine, Jeffrey M., Comery, Thomas A., Arias, Robert, Bowlby, Mark, Martone, Robert, Morrison, John H., Pangalos, Menelas N., Reinhart, Peter H. et al. · 2006 · Proceedings of the National Academy of Sciences
- Cytokine networks in neuroinflammationBurkhard Becher, Sabine Spath, Joan M. Goverman · 2016 · Nature reviews. Immunology
- NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s DiseaseLian, Hong, Yang, Li, Cole, Allysa, Sun, Lu, Chiang, Angie C.-A., Fowler, Stephanie W., Shim, David J., Rodriguez-Rivera, Jennifer, Taglialatela, Giulio, Jankowsky, Joanna L. et al. · 2015 · Neuron
- Lipopolysaccharide-Induced Inflammation Exacerbates Tau Pathology by a Cyclin-Dependent Kinase 5-Mediated Pathway in a Transgenic Model of Alzheimer's DiseaseKitazawa, Masashi, Oddo, Salvatore, Yamasaki, Tritia R., Green, Kim N., LaFerla, Frank M. · 2005 · The Journal of Neuroscience
- Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathologySpangenberg, Elizabeth E., Lee, Rafael J., Najafi, Allison R., Rice, Rachel A., Elmore, Monica R. P., Blurton-Jones, Mathew, West, Brian L., Green, Kim N. · 2016 · Brain
- The β-Secretase BACE1 in Alzheimer’s DiseaseHampel, Harald, Vassar, Robert, De Strooper, Bart, Hardy, John, Willem, Michael, Singh, Neeraj, Zhou, John, Yan, Riqiang, Vanmechelen, Eugeen, De Vos, Ann et al. · 2021 · Biological Psychiatry
- Three dimensions of the amyloid hypothesis: time, space and 'wingmen'Erik S. Musiek, David M. Holtzman · 2015 · Nature Neuroscience
- Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer’s disease NeuronsRavi Rajmohan, P. Hemachandra Reddy · 2016 · Journal of Alzheimer s Disease
- Interaction between Aβ and Tau in the Pathogenesis of Alzheimer’s DiseaseZhang, Huiqin, Wei, Wei, Zhao, Ming, Ma, Lina, Jiang, Xuefan, Pei, Hui, Cao, Yu, Li, Hao · 2021 · International Journal of Biological Sciences
- Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s DiseaseWesseling, Hendrik, Mair, Waltraud, Kumar, Mukesh, Schlaffner, Christoph N., Tang, Shaojun, Beerepoot, Pieter, Fatou, Benoit, Guise, Amanda J., Cheng, Long, Takeda, Shuko et al. · 2020 · Cell
- Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral SclerosisPhuong Hoang Nguyen, Ayyalusamy Ramamoorthy, Bikash Ranjan Sahoo, Jie Zheng, Peter Faller, John E. Straub, Laura Domı́nguez, Joan‐Emma Shea, Nikolay V. Dokholyan, Alfonso De Simone et al. · 2021 · Chemical Reviews
- The genetic epidemiology of neurodegenerative diseaseBertram, L. · 2005 · Journal of Clinical Investigation
- Immune activation in brain aging and neurodegeneration: too much or too little?Lucin, Kurt M., Wyss-Coray, Tony · 2009 · Neuron
- Transport Pathways for Clearance of Human Alzheimer's Amyloid β-Peptide and Apolipoproteins E and J in the Mouse Central Nervous SystemBell, Robert D, Sagare, Abhay P, Friedman, Alan E, Bedi, Gurrinder S, Holtzman, David M, Deane, Rashid, Zlokovic, Berislav V · 2007 · Journal of Cerebral Blood Flow & Metabolism
- Integrating neuroimmune systems in the neurobiology of depressionWohleb, Eric S., Franklin, Tina, Iwata, Masaaki, Duman, Ronald S. · 2016 · Nature Reviews Neuroscience
- Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like TauopathyIba, Michiyo, Guo, Jing L., McBride, Jennifer D., Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y. · 2013 · The Journal of Neuroscience
- Impaired glymphatic function and clearance of tau in an Alzheimer’s disease modelIan F. Harrison, Ozama Ismail, Asif Machhada, Niall C. Colgan, Yolanda Ohene, Payam Nahavandi, Zeshan Ahmed, Alice Fisher, Soraya Meftah, Tracey K. Murray et al. · 2020 · Brain
- Role of Microglia in NeurotraumaLoane, David J., Byrnes, Kimberly R. · 2010 · Neurotherapeutics
- Phagocytosis of Microglia in the Central Nervous System DiseasesRuying Fu, Qingyu Shen, Pengfei Xu, Jin Jun Luo, Yamei Tang · 2014 · Molecular Neurobiology
- A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s diseasethe Dominantly Inherited Alzheimer Network, Barthélemy, Nicolas R., Li, Yan, Joseph-Mathurin, Nelly, Gordon, Brian A., Hassenstab, Jason, Benzinger, Tammie. L. S., Buckles, Virginia, Fagan, Anne M., Perrin, Richard J. et al. · 2020 · Nature Medicine
- Microglia contact induces synapse formation in developing somatosensory cortexMiyamoto, Akiko, Wake, Hiroaki, Ishikawa, Ayako Wendy, Eto, Kei, Shibata, Keisuke, Murakoshi, Hideji, Koizumi, Schuichi, Moorhouse, Andrew J., Yoshimura, Yumiko, Nabekura, Junichi · 2016 · Nature Communications
- Alzheimer’s Disease: Past, Present, and FutureBondi, Mark W., Edmonds, Emily C., Salmon, David P. · 2017 · Journal of the International Neuropsychological Society
- Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer DiseaseCheng‐Xin Gong, Khalid Iqbal · 2008 · Current Medicinal Chemistry
- Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregationHe, Zhuohao, Guo, Jing L, McBride, Jennifer D, Narasimhan, Sneha, Kim, Hyesung, Changolkar, Lakshmi, Zhang, Bin, Gathagan, Ronald J, Yue, Cuiyong, Dengler, Christopher et al. · 2018 · Nature Medicine
- The high-affinity HSP90–CHIP complex recognizes and selectively degrades phosphorylated tau client proteinsDickey, Chad A., Kamal, Adeela, Lundgren, Karen, Klosak, Natalia, Bailey, Rachel M., Dunmore, Judith, Ash, Peter, Shoraka, Sareh, Zlatkovic, Jelena, Eckman, Christopher B. et al. · 2007 · Journal of Clinical Investigation
- Physiological release of endogenous tau is stimulated by neuronal activityPooler, Amy M, Phillips, Emma C, Lau, Dawn H W, Noble, Wendy, Hanger, Diane P · 2013 · The EMBO Reports
- A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse modelPostina, Rolf, Schroeder, Anja, Dewachter, Ilse, Bohl, Juergen, Schmitt, Ulrich, Kojro, Elzbieta, Prinzen, Claudia, Endres, Kristina, Hiemke, Christoph, Blessing, Manfred et al. · 2004 · Journal of Clinical Investigation
- Growing up in a bubble: using germ-free animals to assess the influence of the gut microbiota on brain and behaviorLuczynski, Pauline, McVey Neufeld, Karen-Anne, Oriach, Clara Seira, Clarke, Gerard, Dinan, Timothy G., Cryan, John F. · 2016 · International Journal of Neuropsychopharmacology
- Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease ProgressionBai, Bing, Wang, Xusheng, Li, Yuxin, Chen, Ping-Chung, Yu, Kaiwen, Dey, Kaushik Kumar, Yarbro, Jay M., Han, Xian, Lutz, Brianna M., Rao, Shuquan et al. · 2020 · Neuron
- Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosisViola, Kirsten L., Klein, William L. · 2015 · Acta Neuropathologica
- Tau PET imaging in neurodegenerative tauopathies—still a challengeLeuzy, Antoine, Chiotis, Konstantinos, Lemoine, Laetitia, Gillberg, Per-Göran, Almkvist, Ove, Rodriguez-Vieitez, Elena, Nordberg, Agneta · 2019 · Molecular Psychiatry
- The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementiaSchulz-Schaeffer, Walter J. · 2010 · Acta Neuropathologica
- Protein transmission in neurodegenerative diseasePeng, Chao, Trojanowski, John Q., Lee, Virginia M.-Y. · 2020 · Nature Reviews Neurology
- Glucocorticoids increase amyloid-β and tau pathology in a mouse model of alzheimer’s diseaseGreen, Kim N., Billings, Lauren M., Roozendaal, Benno, McGaugh, James L., LaFerla, Frank M. · 2006 · The Journal of Neuroscience
- Is Alzheimer’s disease a type 3 diabetes? A critical appraisalKandimalla, Ramesh, Thirumala, Vani, Reddy, P. Hemachandra · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Mitochondria at the neuronal presynapse in health and diseaseMichael J. Devine, Josef T. Kittler · 2018 · Nature reviews. Neuroscience
- Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysisHoltman, Inge R, Raj, Divya D, Miller, Jeremy A, Schaafsma, Wandert, Yin, Zhuoran, Brouwer, Nieske, Wes, Paul D, Möller, Thomas, Orre, Marie, Kamphuis, Willem et al. · 2015 · Acta Neuropathologica Communications
- Effects of secreted oligomers of amyloid β‐protein on hippocampal synaptic plasticity: a potent role for trimersTownsend, Matthew, Shankar, Ganesh M., Mehta, Tapan, Walsh, Dominic M., Selkoe, Dennis J. · 2006 · The Journal of Physiology
- Emerging Roles of Exosomes in Normal and Pathological Conditions: New Insights for Diagnosis and Therapeutic ApplicationsJulieta De Toro, Leticia Herschlik, Claudia Waldner, Claudia Mongini · 2015 · Frontiers in Immunology
- Amyloid β-Protein Assembly and Alzheimer DiseaseRobin Roychaudhuri, Mingfeng Yang, Minako M. Hoshi, David B. Teplow · 2008 · Journal of Biological Chemistry
- Validating novel tau positron emission tomography tracer
<scp>[F‐18]‐AV‐1451 (T807)</scp>
on postmortem brain tissueMarquié, Marta, Normandin, Marc D., Vanderburg, Charles R., Costantino, Isabel M., Bien, Elizabeth A., Rycyna, Lisa G., Klunk, William E., Mathis, Chester A., Ikonomovic, Milos D., Debnath, Manik L. et al. · 2015 · Annals of Neurology