Molecular mediators of hepatic steatosis and liver injury

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

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Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action

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Nonalcoholic Fatty Liver Disease

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Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

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Steatohepatitis: A tale of two “hits”?

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

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Nonalcoholic Fatty Liver Disease

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Nonalcoholic Steatohepatitis: Summary of An Aasld Single Topic Conference

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Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

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Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice†

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Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis

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Regulation of Renal Lipid Metabolism, Lipid Accumulation, and Glomerulosclerosis in FVB db/db Mice With Type 2 Diabetes

Wang, Z., Jiang, T., Li, J., Proctor, G., McManaman, J. L., Lucia, S. M., Chua, S. C., & Levi, M. (2005) · Diabetes · doi:10.2337/diabetes.54.8.2328 · Cited by 302

Fatty liver and lipotoxicity

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Non-alcoholic fatty liver disease

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Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

Yamamoto, K., Takahara, K., Oyadomari, S., Okada, T., Sato, T., Harada, A., & Mori, K. (2010) · Molecular Biology of the Cell · doi:10.1091/mbc.e09-02-0133 · Cited by 298

The lysosomal-mitochondrial axis in free fatty acid–induced hepatic lipotoxicity

Li, Z.-Z., Berk, M. P., McIntyre, T. M., Gores, G. J., & Feldstein, A. E. (2008) · Hepatology · doi:10.1002/hep.22183 · Cited by 296

Insulin resistance and obesity in childhood

Chiarelli, F., & Marcovecchio, M. L. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0245 · Cited by 294

Practice guidelines for the diagnosis and management of nonalcoholic fatty liver disease

Loria, P., Adinolfi, L. E., Bellentani, S., Bugianesi, E., Grieco, A., Fargion, S. R., Gasbarrini, A., Loguercio, C., Lonardo, A., Marchesini, G., et al. (2010) · Digestive and Liver Disease · doi:10.1016/j.dld.2010.01.021 · Cited by 293

Nonalcoholic Fatty Liver Disease

Adams, L. A., & Lindor, K. D. (2007) · Annals of Epidemiology · doi:10.1016/j.annepidem.2007.05.013 · Cited by 291

Metformin in non-alcoholic fatty liver disease: A systematic review and meta-analysis

LI, Y., LIU, L., WANG, B., WANG, J., & CHEN, D. (2013) · Biomedical Reports · doi:10.3892/br.2012.18 · Cited by 290

Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance

Leavens, K. F., Easton, R., Shulman, G. I., Previs, S. F., & Birnbaum, M. J. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.10.004 · Cited by 289

Liver X receptor in cooperation with SREBP‐1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease

Higuchi, N., Kato, M., Shundo, Y., Tajiri, H., Tanaka, M., Yamashita, N., Kohjima, M., Kotoh, K., Nakamuta, M., Takayanagi, R., et al. (2008) · Hepatology Research · doi:10.1111/j.1872-034x.2008.00382.x · Cited by 290

Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

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SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease

Shin, J., He, M., Liu, Y., Paredes, S., Villanova, L., Brown, K., Qiu, X., Nabavi, N., Mohrin, M., Wojnoonski, K., et al. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.10.007 · Cited by 287

Non-alcoholic fatty liver disease pathogenesis: The present and the future

Petta, S., Muratore, C., & Craxı̀, A. (2009) · Digestive and Liver Disease · doi:10.1016/j.dld.2009.01.004 · Cited by 287

Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis

Gastaldelli, A., Harrison, S. A., Belfort-Aguilar, R., Hardies, L. J., Balas, B., Schenker, S., & Cusi, K. (2009) · Hepatology · doi:10.1002/hep.23116 · Cited by 285

Role of mitochondria in non‐alcoholic fatty liver disease

Pessayre, D. (2007) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04640.x · Cited by 287

Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ

Kim, K. H., Shin, H., Kim, K., Choi, H. M., Rhee, S. H., Moon, H., Kim, H. H., Yang, U. S., Yu, D., & Cheong, J. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.03.039 · Cited by 281

Inter-organ cross-talk in metabolic syndrome

Priest, C., & Tontonoz, P. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0145-5 · Cited by 279

Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease

Povero, D., Eguchi, A., Li, H., Johnson, C. D., Papouchado, B. G., Wree, A., Messer, K. S., & Feldstein, A. E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113651 · Cited by 280

Overproduction of VLDL 1 Driven by Hyperglycemia Is a Dominant Feature of Diabetic Dyslipidemia

Adiels, M., Borén, J., CASLAKE, M. J., Stewart, P., Soro, A., Westerbacka, J., Wennberg, B., Olofsson, S., Packard, C. J., & Taskinen, M. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000172689.53992.25 · Cited by 275

Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase

SHANG, J., CHEN, L.-L., XIAO, F.-X., SUN, H., DING, H.-C., & XIAO, H. (2008) · Acta Pharmacologica Sinica · doi:10.1111/j.1745-7254.2008.00807.x · Cited by 274

Free radical biology for medicine: learning from nonalcoholic fatty liver disease

Serviddio, G., Bellanti, F., & Vendemiale, G. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.08.174 · Cited by 272

Roles of the peroxisome proliferator-activated receptors (PPARs) in the pathogenesis of nonalcoholic fatty liver disease (NAFLD)

Qiu, Y.-Y., Zhang, J., Zeng, F.-Y., & Zhu, Y. Z. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106786 · Cited by 271

Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis

Yetukuri, L., Katajamaa, M., Medina‐Gómez, G., Seppänen‐Laakso, T., Vidal‐Puig, A., & Orešič, M. (2007) · BMC Systems Biology · doi:10.1186/1752-0509-1-12 · Cited by 270

Polystyrene microplastic exposure disturbs hepatic glycolipid metabolism at the physiological, biochemical, and transcriptomic levels in adult zebrafish

Zhao, Y., Bao, Z., Wan, Z., Fu, Z., & Jin, Y. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.136279 · Cited by 270

Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis

Lee, K., Wu, P.-S., & Lin, H. (2022) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2022.0237 · Cited by 269

Adiponectin, a key adipokine in obesity related liver diseases.

Buechler, C., Wanninger, J., & Neumeier, M. (2011) · PubMed · doi:10.3748/wjg.v17.i23.2801 · Cited by 264

Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western‐style diet in C57/BL6J mice

Kobori, M., Masumoto, S., Akimoto, Y., & Oike, H. (2010) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000392 · Cited by 264

Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high‐fat diet

Ito, M., Suzuki, J., Tsujioka, S., Sasaki, M., Gomori, A., Shirakura, T., Hirose, H., Ito, M., Ishihara, A., Iwaasa, H., et al. (2007) · Hepatology Research · doi:10.1111/j.1872-034x.2007.00008.x · Cited by 263

Chronic intermittent hypoxia predisposes to liver injury†

Savransky, V., Nanayakkara, A., Vivero, A., Li, J., Bevans‐Fonti, S., Smith, P. L., Torbenson, M. S., & Polotsky, V. Y. (2007) · Hepatology · doi:10.1002/hep.21593 · Cited by 262

Advances in Pediatric Nonalcoholic Fatty Liver Disease†

Loomba, R. S., Sirlin, C. B., Schwimmer, J. B., & Lavine, J. E. (2009) · Hepatology · doi:10.1002/hep.23119 · Cited by 262

The Effect of Inflammatory Cytokines in Alcoholic Liver Disease

Kawaratani, H., Tsujimoto, T., Douhara, A., Takaya, H., Moriya, K., Namisaki, T., Noguchi, R., Yoshiji, H., Fujimoto, M., & Fukui, H. (2013) · Mediators of Inflammation · doi:10.1155/2013/495156 · Cited by 261

Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome

Pawlik, T. M., Olino, K. L., Gleisner, A., Torbenson, M. S., Schulick, R. D., & Choti, M. A. (2007) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-007-0149-4 · Cited by 260

CMO1 Deficiency Abolishes Vitamin A Production from β-Carotene and Alters Lipid Metabolism in Mice

Hessel, S., Eichinger, A., Isken, A., Amengual, J., Hunzelmann, S., Hoeller, U., Elste, V., Hunziker, W., Goralczyk, R., Oberhauser, V., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706763200 · Cited by 259

Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications

Alkhouri, N., Carter-Kent, C. A., & Feldstein, A. E. (2011) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.11.6 · Cited by 259

A Model of Insulin Resistance and Nonalcoholic Steatohepatitis in Rats

Svegliati‐Baroni, G., Candelaresi, C., Saccomanno, S., Ferretti, G., Bachetti, T., Marzioni, M., Minicis, S. D., Nobili, L., Salzano, R., Omenetti, A., et al. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.050953 · Cited by 258

Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia

Li, J., Savransky, V., Nanayakkara, A., Smith, P. L., O'Donnell, C. P., & Polotsky, V. Y. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01081.2006 · Cited by 255

High Prevalence of Small Intestinal Bacterial Overgrowth in Patients with Morbid Obesity: A Contributor to Severe Hepatic Steatosis

Sabaté, J., Jouët, P., Harnois, F., Mechler, C., Msika, S., Grossin, M., & Coffin, B. (2008) · Obesity Surgery · doi:10.1007/s11695-007-9398-2 · Cited by 255

SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity

Lee, D. H., Park, J. S., Lee, Y. S., Han, J., Lee, D., Kwon, S. W., Han, D. H., Lee, Y., & Bae, S. H. (2020) · Autophagy · doi:10.1080/15548627.2020.1712108 · Cited by 256

Non-alcoholic Steatohepatitis and Cancer

Bugianesi, E. (2007) · Clinics in Liver Disease · doi:10.1016/j.cld.2007.02.006 · Cited by 248

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

Fu, J., Gerhardt, H., McDaniel, J. M., Xia, B., Liu, X., Ivanciu, L., Ny, A., Hermans, K., Silasi‐Mansat, R., McGee, S., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36077 · Cited by 246

Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels # †

Haring, R., Wallaschofski, H., Nauck, M. A., Dörr, M., Baumeister, S. E., & Völzke, H. (2009) · Hepatology · doi:10.1002/hep.23135 · Cited by 246

Benefits of lifestyle modification in NAFLD

Harrison, S. A., & Day, C. P. (2007) · Gut · doi:10.1136/gut.2006.112094 · Cited by 246

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

Subramanian, S., Goodspeed, L., Wang, S., Kim, J. K., Zeng, L., Ioannou, G. N., Haigh, W. G., Yeh, M. M., Kowdley, K. V., O’Brien, K. D., et al. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m016246 · Cited by 244

Nonalcoholic Fatty Liver Disease: Focus on Lipoprotein and Lipid Deregulation

Tacer, K. F., & Rozman, D. (2011) · Journal of Lipids · doi:10.1155/2011/783976 · Cited by 242

A phase 2 clinical trial of metformin as a treatment for non‐diabetic paediatric non‐alcoholic steatohepatitis

Schwimmer, J. B., Middleton, M. S., Deutsch, R., & Lavine, J. E. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02420.x · Cited by 242

Mechanisms of Disease: adipocytokines and visceral adipose tissue—emerging role in nonalcoholic fatty liver disease

Schäffler, A., Schölmerich, J., & Büchler, C. (2005) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep0186 · Cited by 240

Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD)

Song, J., Costa, K. A. D., Fischer, L. M., Kohlmeier, M., Kwock, L., Wang, S., & Zeisel, S. H. (2005) · The FASEB Journal · doi:10.1096/fj.04-3580com · Cited by 237

Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders

Torres, N., Torre-Villalvazo, I., & Tovar, A. R. (2005) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2005.11.005 · Cited by 235

Susceptibility of Nrf2-Null Mice to Steatohepatitis and Cirrhosis upon Consumption of a High-Fat Diet Is Associated with Oxidative Stress, Perturbation of the Unfolded Protein Response, and Disturbance in the Expression of Metabolic Enzymes but Not with Insulin Resistance

Meakin, P. J., Chowdhry, S., Sharma, R. S., Ashford, F. B., Walsh, S. V., McCrimmon, R. J., Dinkova‐Kostova, A. T., Dillon, J. F., Hayes, J. D., & Ashford, M. L. J. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.00677-14 · Cited by 233

ChREBP: A Glucose-activated Transcription Factor Involved in the Development of Metabolic Syndrome

Iizuka, K., & Horikawa, Y. (2008) · Endocrine Journal · doi:10.1507/endocrj.k07e-110 · Cited by 232

Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy

Cortés, V., Curtis, D. E., Sukumaran, S., Shao, X., Parameswara, V., Rashid, S., Smith, A. R., Ren, J., Esser, V., Hammer, R. E., et al. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.01.002 · Cited by 231

Coffee Reduces Liver Damage in a Rat Model of Steatohepatitis: The Underlying Mechanisms and the Role of Polyphenols and Melanoidins

Vitaglione, P., Morisco, F., Mazzone, G., Amoruso, D. C., Ribecco, M. T. S., Romano, A., Fogliano, V., Caporaso, N., & D’Argenio, G. (2010) · Hepatology · doi:10.1002/hep.23902 · Cited by 231

Stearoyl-CoA Desaturase-1 Mediates the Pro-lipogenic Effects of Dietary Saturated Fat

Sampath, H., Miyazaki, M., Dobrzyń, A., & Ntambi, J. M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m610158200 · Cited by 229

Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy†

Javor, E. D., Ghany, M. G., Cochran, E. K., Oral, E. A., DePaoli, A. M., Premkumar, A., Kleiner, D. E., & Gorden, P. (2005) · Hepatology · doi:10.1002/hep.20672 · Cited by 228

Insulin Resistance Accelerates a Dietary Rat Model of Nonalcoholic Steatohepatitis

Ota, T., Takamura, T., Kurita, S., Matsuzawa, N., Kita, Y., Uno, M., Akahori, H., Misu, H., Sakurai, M., Zen, Y., et al. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.10.014 · Cited by 227

An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis

Crooke, R. M., Graham, M. J., Lemonidis, K. M., Whipple, C. P., Koo, S., & Perera, R. J. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400492-jlr200 · Cited by 227

Long-Term Efficacy of Leptin Replacement in Patients With Generalized Lipodystrophy

Javor, E. D., Cochran, E. K., Musso, C., Young, J. R., DePaoli, A. M., & Gorden, P. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1994 · Cited by 226

Resveratrol inhibits nonalcoholic fatty liver disease in rats

Bujanda, L., Hijona, E., Larzábal, M., Beraza, M., Aldazábal, P., García‐Urkía, N., Sarasqueta, C., Cosme, Á., Irastorza, B., González, A., et al. (2008) · BMC Gastroenterology · doi:10.1186/1471-230x-8-40 · Cited by 226

PPARα activation is essential for HCV core protein–induced hepatic steatosis and hepatocellular carcinoma in mice

Tanaka, N., Moriya, K., Kiyosawa, K., Koike, K., Gonzalez, F. J., & Aoyama, T. (2008) · Journal of Clinical Investigation · doi:10.1172/jci33594 · Cited by 225

Role of Cholesterol‐Associated Steatohepatitis in the Development of NASH

Horn, C. L., Morales, A. L., Savard, C. E., Farrell, G. C., & Ioannou, G. N. (2021) · Hepatology Communications · doi:10.1002/hep4.1801 · Cited by 225

Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates

Wang, P., Ji, Y., Zhang, X., Zhao, L., Yan, Z.-Z., Zhang, P., Shen, L., Yang, X., Fang, J., Tian, S., et al. (2017) · Nature Medicine · doi:10.1038/nm.4290 · Cited by 221

CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells

Koda, Y., Teratani, T., Chu, P.-S., Hagihara, Y., Mikami, Y., Harada, Y., Tsujikawa, H., Miyamoto, K., Suzuki, T., Taniki, N., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24734-0 · Cited by 219

Non-alcoholic fatty liver disease: the hepatic consequence of obesity and the metabolic syndrome

Moore, J. B. (2010) · Proceedings of The Nutrition Society · doi:10.1017/s0029665110000030 · Cited by 219

Molecular Pathogenesis of NASH

Caligiuri, A., Gentilini, A., & Marra, F. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17091575 · Cited by 219

Non-alcoholic steatohepatitis: effect of Roux-en-Y gastric bypass surgery

Barker, K. B., Palekar, N. A., Bowers, S. P., Goldberg, J. E., Pulcini, J. P., & Harrison, S. A. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00419.x · Cited by 218

Autophagy in nonalcoholic steatohepatitis

Amir, M., & Czaja, M. J. (2011) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.11.4 · Cited by 218

Obstructive Sleep Apnea, Insulin Resistance, and Steatohepatitis in Severe Obesity

Polotsky, V. Y., Patil, S. P., Savransky, V., Laffan, A. M., Bevans‐Fonti, S., Frame, L. A., Steele, K., Schweizter, M. A., Clark, J. M., Torbenson, M. S., et al. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200804-608oc · Cited by 218

The Role of Quercetin, a Flavonoid in the Management of Pathogenesis Through Regulation of Oxidative Stress, Inflammation, and Biological Activities

Alharbi, H. O., Alshebremi, M., Babiker, A. Y., & Rahmani, A. H. (2025) · Biomolecules · doi:10.3390/biom15010151 · Cited by 216

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice #

Wang, Q. A., Jiang, L., Wang, J., Li, S., Yu, Y., You, J., Zeng, R., Gao, X., Rui, L., Li, W., et al. (2008) · Hepatology · doi:10.1002/hep.22774 · Cited by 215

Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver

Savransky, V., Bevans‐Fonti, S., Nanayakkara, A., Li, J., Smith, P. L., Torbenson, M. S., & Polotsky, V. Y. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00145.2007 · Cited by 215

Lipid-Induced Toxicity Stimulates Hepatocytes to Release Angiogenic Microparticles That Require Vanin-1 for Uptake by Endothelial Cells

Povero, D., Eguchi, A., Niesman, I. R., Andronikou, N., du Jeu, X. D. M., Mulya, A., Berk, M. P., Lazić, M., Thapaliya, S., Parola, M., et al. (2013) · Science Signaling · doi:10.1126/scisignal.2004512 · Cited by 213

Hepatic Crown-Like Structure: A Unique Histological Feature in Non-Alcoholic Steatohepatitis in Mice and Humans

Itoh, M., Kato, H., Suganami, T., Konuma, K., Marumoto, Y., Terai, S., Sakugawa, H., Kanai, S., Hamaguchi, M., Fukaishi, T., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082163 · Cited by 211

Intermittent Hypoxia Exacerbates Metabolic Effects of Diet‐Induced Obesity

Drager, L. F., Li, J., Reinke, C., Bevans‐Fonti, S., Jun, J. C., & Polotsky, V. Y. (2011) · Obesity · doi:10.1038/oby.2011.240 · Cited by 208

Mechanisms of Lipotoxicity in NAFLD and Clinical Implications

Ibrahim, S. H., Kohli, R., & Gores, G. J. (2011) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e31822578db · Cited by 207

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Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver

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Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis

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Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis

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Cell-to-Cell Heterogeneity in Lipid Droplets Suggests a Mechanism to Reduce Lipotoxicity

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