Autophagy in cell death: an innocent convict?

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

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AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

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The role of autophagy during the early neonatal starvation period

Kuma, A., Hatano, M., Matsui, M., Yamamoto, A., Nakaya, H., Yoshimori, T., Ohsumi, Y., Tokuhisa, T., & Mizushima, N. (2004) · Nature · doi:10.1038/nature03029 · Cited by 2,865

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Ravikumar, B., Vacher, C., Berger, Z., Davies, J. E., Luo, S., Oroz, L. G., Scaravilli, F., Easton, D. F., Duden, R., O'Kane, C. J., et al. (2004) · Nature Genetics · doi:10.1038/ng1362 · Cited by 2,347

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Qu, X., Yu, J., Bhagat, G., Furuya, N., Hibshoosh, H., Troxel, A., Rosen, J., Eskelinen, E.-L., Mizushima, N., Ohsumi, Y., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci20039 · Cited by 2,311

Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

Gutierrez, M. G., Master, S. S., Singh, S. B., Taylor, G. A., Colombo, M. I., & Deretic, V. (2004) · Cell · doi:10.1016/j.cell.2004.11.038 · Cited by 2,252

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Yue, Z., Jin, S., Yang, C., Levine, A. J., & Heintz, N. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2436255100 · Cited by 2,116

Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

Cuervo, A. M., Stefanis, L., Fredenburg, R., Lansbury, P. T., & Sulzer, D. (2004) · Science · doi:10.1126/science.1101738 · Cited by 2,024

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

Lum, J. J., Bauer, D. E., Kong, M., Harris, M. H., Li, C., Lindsten, T., & Thompson, C. B. (2005) · Cell · doi:10.1016/j.cell.2004.11.046 · Cited by 1,487

Autophagy fights disease through cellular self-digestion

Mizushima, N., Levine, B., Cuervo, A. M., & Klionsky, D. J. (2008) · Nature · doi:10.1038/nature06639 · Cited by 6,452

Mitochondrial membrane permeabilization in cell death

Kroemer, G., Galluzzi, L., & Brenner, C. (2007) · Physiological Reviews · doi:10.1152/physrev.00013.2006 · Cited by 3,598

Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy

Pattingre, S., Tassa, A., Qu, X., Garuti, R., Liang, X. H., Mizushima, N., Packer, M., Schneider, M. D., & Levine, B. (2005) · Cell · doi:10.1016/j.cell.2005.07.002 · Cited by 3,536

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J.-I., Tanida, I., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., et al. (2006) · Nature · doi:10.1038/nature04723 · Cited by 3,500

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., El-Deiry, W. S., Golstein, P., Green, D. R., et al. (2009) · Cell Death & Differentiation · doi:10.1038/cdd.2008.150 · Cited by 3,399

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082

Programmed Cell Death in Animal Development and Disease

Fuchs, Y., & Steller, H. (2011) · Cell · doi:10.1016/j.cell.2011.10.033 · Cited by 1,915

Selective degradation of mitochondria by mitophagy

Kim, I., Rodriguez-Enriquez, S., & Lemasters, J. J. (2007) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2007.03.034 · Cited by 1,558

Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion: Roles of AMP-Activated Protein Kinase and Beclin 1 in Mediating Autophagy

Matsui, Y., Takagi, H., Qu, X., Abdellatif, M., Sakoda, H., Asano, T., Levine, B., & Sadoshima, J. (2007) · Circulation Research · doi:10.1161/01.res.0000261924.76669.36 · Cited by 1,505

Autophagic cell death: the story of a misnomer

Kroemer, G., & Levine, B. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2529 · Cited by 1,453

Regulation of autophagy by cytoplasmic p53

Tasdemir, E., Maiuri, M. C., Galluzzi, L., Vitale, I., Djavaheri-Mergny, M., D'Amelio, M., Criollo, A., Morselli, E., Zhu, C., Harper, F., et al. (2008) · Nature Cell Biology · doi:10.1038/ncb1730 · Cited by 1,132

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

Liang, C., Feng, P., Ku, B., Dotan, I., Canaani, D., Oh, B.-H., & Jung, J. U. (2006) · Nature Cell Biology · doi:10.1038/ncb1426 · Cited by 919

Toll-like Receptor 4 Is a Sensor for Autophagy Associated with Innate Immunity

Xu, Y., Jagannath, C., Liu, X.-D., Sharafkhaneh, A., Kolodziejska, K. E., & Eissa, N. T. (2007) · Immunity · doi:10.1016/j.immuni.2007.05.022 · Cited by 880

HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein

Orvedahl, A., Alexander, D., Tallóczy, Z., Sun, Q., Wei, Y., Zhang, W., Burns, D., Leib, D. A., & Levine, B. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2006.12.001 · Cited by 857

Consensus guidelines for the detection of immunogenic cell death

Kepp, O., Senovilla, L., Vitale, I., Vacchelli, E., Adjemian, S., Agostinis, P., Apetoh, L., Aranda, F., Barnaba, V., Bloy, N., et al. (2014) · OncoImmunology · doi:10.4161/21624011.2014.955691 · Cited by 832

Cell death modalities: classification and pathophysiological implications

Galluzzi, L., Maiuri, M. C., Vitale, I., Zischka, H., Castedo, M., Zitvogel, L., & Kroemer, G. (2007) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4402148 · Cited by 832

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

Hansen, M., Chandra, A., Mitic, L. L., Onken, B., Driscoll, M., & Kenyon, C. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.0040024 · Cited by 766

Autophagy, amyloidogenesis and Alzheimer disease

Nixon, R. A. (2007) · Journal of Cell Science · doi:10.1242/jcs.019265 · Cited by 749

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

Moreira, P. I., Carvalho, C., Zhu, X., Smith, M. A., & Perry, G. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.10.006 · Cited by 734

Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis

Grootaert, M. O. J., Moulis, M., Roth, L., Martinet, W., Vindis, C., Bennett, M. R., & De Meyer, G. R. Y. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy007 · Cited by 606

Autosis is a Na + ,K + -ATPase–regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia–ischemia

Liu, Y., Shoji-Kawata, S., Sumpter, R. M., Wei, Y., Ginet, V., Zhang, L., Posner, B., Tran, K. A., Green, D. R., Xavier, R. J., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1319661110 · Cited by 607

Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila

Berry, D. L., & Baehrecke, E. H. (2007) · Cell · doi:10.1016/j.cell.2007.10.048 · Cited by 602

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

Fung, C., Lock, R., Gao, S., Salas, E., & Debnath, J. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-10-1092 · Cited by 558

The Role of Autophagy in the Heart

Sciarretta, S., Maejima, Y., Zablocki, D., & Sadoshima, J. (2018) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021317-121427 · Cited by 547

Dual role of autophagy in hallmarks of cancer

Singh, S. S., Vats, S., Chia, A. Y.-Q., Tan, T. Z., Deng, S., Ong, M. S., Arfuso, F., Yap, C. T., Goh, B. C., Sethi, G., et al. (2018) · Oncogene · doi:10.1038/s41388-017-0046-6 · Cited by 542

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

Colell, A., Ricci, J.-E., Tait, S., Milasta, S., Maurer, U., Bouchier-Hayes, L., Fitzgerald, P., Guio-Carrion, A., Waterhouse, N. J., Li, C. W., et al. (2007) · Cell · doi:10.1016/j.cell.2007.03.045 · Cited by 516

Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury

Koike, M., Shibata, M., Tadakoshi, M., Gotoh, K., Komatsu, M., Waguri, S., Kawahara, N., Kuida, K., Nagata, S., Kominami, E., et al. (2008) · The American Journal of Pathology · doi:10.2353/ajpath.2008.070876 · Cited by 486

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

Florey, O., Kim, S. E., Sandoval, C. P., Haynes, C. M., & Overholtzer, M. (2011) · Nature Cell Biology · doi:10.1038/ncb2363 · Cited by 459

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

Chen, Z.-H., Kim, H. P., Sciurba, F. C., Lee, S.-J., Feghali-Bostwick, C., Stolz, D. B., Dhir, R., Landreneau, R. J., Schuchert, M. J., Yousem, S. A., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003316 · Cited by 459

Autophagy: A Key Regulator of Homeostasis and Disease: An Overview of Molecular Mechanisms and Modulators

Gómez-Virgilio, L., Silva-Lucero, M.-D.-C., Flores-Morelos, D.-S., Gallardo-Nieto, J., Lopez-Toledo, G., Abarca-Fernandez, A.-M., Zacapala-Gómez, A.-E., Luna-Muñoz, J., Montiel-Sosa, F., Soto-Rojas, L. O., et al. (2022) · Cells · doi:10.3390/cells11152262 · Cited by 431

NF-κB Activation Represses Tumor Necrosis Factor-α-induced Autophagy

Djavaheri-Mergny, M., Amelotti, M., Mathieu, J., Besançon, F., Bauvy, C., Souquère, S., Pierron, G., & Codogno, P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602097200 · Cited by 407

Cancer cell survival during detachment from the ECM: multiple barriers to tumour progression

Buchheit, C. L., Weigel, K. J., & Schafer, Z. T. (2014) · Nature Reviews Cancer · doi:10.1038/nrc3789 · Cited by 367

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

Degtyarev, M., De Mazière, A., Orr, C., Lin, J., Lee, B. B., Tien, J. Y., Prior, W. W., van Dijk, S., Wu, H., Gray, D. C., et al. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200801099 · Cited by 366

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Golestaneh, N., Chu, Y., Xiao, Y.-Y., Stoleru, G. L., & Theos, A. C. (2017) · Cell Death & Disease · doi:10.1038/cddis.2016.453 · Cited by 357

Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease

Dai, D.-F., Chen, T., Johnson, S. C., Szeto, H., & Rabinovitch, P. S. (2012) · Antioxidants & Redox Signaling · doi:10.1089/ars.2011.4179 · Cited by 334

Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation

Kang, C., You, Y.-J., & Avery, L. (2007) · Genes & Development · doi:10.1101/gad.1573107 · Cited by 294

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

Thorburn, J., Horita, H., Redzic, J., Hansen, K., Frankel, A. E., & Thorburn, A. (2009) · Cell Death & Differentiation · doi:10.1038/cdd.2008.143 · Cited by 268

Recent advances in our understanding of neurodegeneration

Jellinger, K. A. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0240-y · Cited by 274

MicroRNA-155 Promotes Autophagy to Eliminate Intracellular Mycobacteria by Targeting Rheb

Wang, J., Yang, K., Zhou, L., MinhaoWu, Wu, Y., Zhu, M., Lai, X., Chen, T., Feng, L., Li, M., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003697 · Cited by 265

Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease

Gan-Or, Z., Dion, P. A., & Rouleau, G. A. (2015) · Autophagy · doi:10.1080/15548627.2015.1067364 · Cited by 260

Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis

Sasaki, S. (2011) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3182160690 · Cited by 249

Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1

Gump, J. M., Staskiewicz, L., Morgan, M. J., Bamberg, A., Riches, D. W. H., & Thorburn, A. (2014) · Nature Cell Biology · doi:10.1038/ncb2886 · Cited by 230

Active Ras Triggers Death in Glioblastoma Cells through Hyperstimulation of Macropinocytosis

Overmeyer, J. H., Kaul, A., Johnson, E. E., & Maltese, W. A. (2008) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-07-2036 · Cited by 229

Regulation of Autophagy by Sphingosine Kinase 1 and Its Role in Cell Survival during Nutrient Starvation

Lavieu, G., Scarlatti, F., Sala, G., Carpentier, S., Levade, T., Ghidoni, R., Botti, J., & Codogno, P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m506182200 · Cited by 225

The Pancreatitis-induced Vacuole Membrane Protein 1 Triggers Autophagy in Mammalian Cells

Ropolo, A., Grasso, D., Pardo, R., Sacchetti, M. L., Archange, C., Re, A. L., Seux, M., Nowak, J., Gonzalez, C. D., Iovanna, J. L., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706956200 · Cited by 223

Autophagic Stress in Neuronal Injury and Disease

Chu, C. T. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000229233.75253.be · Cited by 211

The link between immunity, autoimmunity and endometriosis: a literature update

Zhang, T., De Carolis, C., Man, G. C. W., & Wang, C. C. (2018) · Autoimmunity Reviews · doi:10.1016/j.autrev.2018.03.017 · Cited by 196

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

Qadir, M. A., Kwok, B., Dragowska, W. H., To, K. H., Le, D., Bally, M. B., & Gorski, S. M. (2008) · Breast Cancer Research and Treatment · doi:10.1007/s10549-007-9873-4 · Cited by 201

Regulation of lipid droplets by autophagy

Dong, H., & Czaja, M. J. (2011) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2011.02.003 · Cited by 197

Uba1 functions in Atg7- and Atg3-independent autophagy

Chang, T.-K., Shravage, B. V., Hayes, S. D., Powers, C. M., Simin, R. T., Wade Harper, J., & Baehrecke, E. H. (2013) · Nature Cell Biology · doi:10.1038/ncb2804 · Cited by 187

Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis

Hou, Y.-C. C., Chittaranjan, S., Barbosa, S. G., McCall, K., & Gorski, S. M. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200712091 · Cited by 180

Inhibition of autophagy at a late stage enhances imatinib‐induced cytotoxicity in human malignant glioma cells

Shingu, T., Fujiwara, K., Bögler, O., Akiyama, Y., Moritake, K., Shinojima, N., Tamada, Y., Yokoyama, T., & Kondo, S. (2009) · International Journal of Cancer · doi:10.1002/ijc.24030 · Cited by 174

Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae

Gutierrez, M. G., Saka, H. A., Chinen, I., Zoppino, F. C. M., Yoshimori, T., Bocco, J. L., & Colombo, M. I. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601437104 · Cited by 174

Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease

Cordero, M. D., De Miguel, M., Moreno Fernández, A. M., Carmona López, I. M., Garrido Maraver, J., Cotán, D., Gómez Izquierdo, L., Bonal, P., Campa, F., Bullon, P., et al. (2010) · Arthritis Research & Therapy · doi:10.1186/ar2918 · Cited by 165

Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

Nah, J., Zhai, P., Huang, C.-Y., Fernández, Á. F., Mareedu, S., Levine, B., & Sadoshima, J. (2020) · Journal of Clinical Investigation · doi:10.1172/jci132366 · Cited by 150

Following Cytochrome c Release, Autophagy Is Inhibited during Chemotherapy-Induced Apoptosis by Caspase 8–Mediated Cleavage of Beclin 1

Li, H., Wang, P., Sun, Q., Ding, W.-X., Yin, X.-M., Sobol, R. W., Stolz, D. B., Yu, J., & Zhang, L. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-4475 · Cited by 150

Defective autophagy in atherosclerosis: to die or to senesce?

Grootaert, M. O. J., Roth, L., Schrijvers, D. M., De Meyer, G. R. Y., & Martinet, W. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/7687083 · Cited by 147

Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)

Qing, G., Yan, P., & Xiao, G. (2006) · Cell Research · doi:10.1038/sj.cr.7310109 · Cited by 140

Role of the inflammation-autophagy-senescence integrative network in osteoarthritis

Vinatier, C., Domínguez, E., Guicheux, J., & Caramés, B. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00706 · Cited by 135

The autophagic response to nutrient deprivation in the hl‐1 cardiac myocyte is modulated by Bcl‐2 and sarco/endoplasmic reticulum calcium stores

Brady, N. R., Hamacher‐Brady, A., Yuan, H., & Gottlieb, R. A. (2007) · The FEBS Journal · doi:10.1111/j.1742-4658.2007.05849.x · Cited by 137

Autophagy in the eye: implications for ocular cell health.

Frost, L. S., Mitchell, C. H., & Boesze-Battaglia, K. (2014) · Experimental Eye Research · doi:10.1016/j.exer.2014.04.010 · Cited by 134

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

Castino, R., Lazzeri, G., Lenzi, P., Bellio, N., Follo, C., Ferrucci, M., Fornai, F., & Isidoro, C. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05488.x · Cited by 115

Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes

Trincheri, N. F., Follo, C., Nicotra, G., Peracchio, C., Castino, R., & Isidoro, C. (2008) · Carcinogenesis · doi:10.1093/carcin/bgm271 · Cited by 109

The role of autophagy in unilateral ureteral obstruction rat model

KIM, W., NAM, S. A., SONG, H. C., KO, J. S., PARK, S. H., KIM, H. L., CHOI, E. J., KIM, Y., KIM, J., & KIM, Y. K. (2012) · Nephrology · doi:10.1111/j.1440-1797.2011.01541.x · Cited by 108

Eaten alive: novel insights into autophagy from multicellular model systems

Zhang, H., & Baehrecke, E. H. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.03.001 · Cited by 102

Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice

Arakawa, S., Tsujioka, M., Yoshida, T., Tajima-Sakurai, H., Nishida, Y., Matsuoka, Y., Yoshino, I., Tsujimoto, Y., & Shimizu, S. (2017) · Cell Death & Differentiation · doi:10.1038/cdd.2017.84 · Cited by 94

Role of autophagy in diabetes and mitochondria

Jung, H. S., & Lee, M. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05614.x · Cited by 92

Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence

Drullion, C., Trégoat, C., Lagarde, V, Tan, S., Gioia, R., Priault, M., Djavaheri-Mergny, M., Brisson, A., Auberger, P., Mahon, F.-X., et al. (2012) · Cell Death & Disease · doi:10.1038/cddis.2012.111 · Cited by 88

Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication

Niedelman, W., Sprokholt, J. K., Clough, B., Frickel, E.-M., & Saeij, J. P. J. (2013) · Infection and Immunity · doi:10.1128/iai.00416-13 · Cited by 81

zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function

Herzog, C., Yang, C., Holmes, A., & Kaushal, G. P. (2012) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00659.2011 · Cited by 82

Targeted killing of a mammalian cell based upon its specialized metabolic state

Alexander, P. B., Wang, J., & McKnight, S. L. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1111312108 · Cited by 64

Autophagy genesSmatg8andSmatg4are required for fruiting-body development, vegetative growth and ascospore germination in the filamentous ascomyceteSordaria macrospora

Voigt, O., & Pöggeler, S. (2013) · Autophagy · doi:10.4161/auto.22398 · Cited by 60

SNF4Aγ, the Drosophila AMPK γ subunit is required for regulation of developmental and stress-induced autophagy

Lippai, M., Csikós, G., Maróy, P., Lukácsovich, T., Juhász, G., & Sass, M. (2008) · Autophagy · doi:10.4161/auto.5719 · Cited by 56

Cell death and lumen formation in spheroids of MCF-7 cells

Amaral, D. B. J., Urabayashi, S. M., & Machado‐Santelli, M. G. (2010) · Cell Biology International · doi:10.1042/cbi20090024 · Cited by 46

BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells

Sharma, A., Singh, K., Mazumder, S., Hill, B. T., Kalaycio, M., & Almasan, A. (2013) · Cell Death & Disease · doi:10.1038/cddis.2013.155 · Cited by 39

Active interaction mapping reveals the hierarchical organization of autophagy

Kramer, M. H., Farré, J.-C., Mitra, K., Yu, M. K., Ono, K., Demchak, B., Licon, K., Flagg, M., Balakrishnan, R., Cherry, J. M., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2016.12.024 · Cited by 31

Expression of cFLIPL Determines the Basal Interaction of Bcl‐2 With Beclin‐1 and Regulates p53 Dependent Ubiquitination of Beclin‐1 During Autophagic Stress

Ranjan, K., & Pathak, C. (2016) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25474 · Cited by 19