The DOI matches its Crossref record; 100 of the 100 references it cites were found in a registry or an index.
Cortical Activations During Auditory Verbal Hallucinations in Schizophrenia: A Coordinate-Based Meta-Analysis
Abstract
OBJECTIVE: Auditory verbal hallucinations (AVHs) constitute severe, incapacitating symptoms of schizophrenia. Despite increasing interest in the functional exploration of AVHs, the available findings remain difficult to integrate because of their considerable variability. The authors' aim was to perform a robust quantitative review of existing functional data in order to elucidate consistent patterns observed during the emergence of AVHs and to orient new pathophysiological models of hallucinations. METHOD: Ten positron emission tomography or functional magnetic resonance imaging studies were selected for the meta-analysis after systematic review. A total of 68 patients with schizophrenia spectrum disorders experiencing AVHs during scanning were included. According to a random-effects activation likelihood estimation algorithm, stereotaxic coordinates of 129 foci, reported as significant in the source studies, were extracted and computed to estimate the brain locations most consistently associated with AVHs across studies (cluster-extent threshold: 200 mm³). RESULTS: Patients experiencing AVHs demonstrated significantly increased activation likelihoods in a bilateral neural network, including the Broca's area (activation likelihood estimation=1.84×10⁻³), anterior insula (1.78×10⁻³), precentral gyrus (1.46×10⁻³), frontal operculum (1.29×10⁻³), middle and superior temporal gyri (1.59×10⁻³), inferior parietal lobule (1.33×10⁻³), and hippocampus/parahippocampal region (1.90×10⁻³). CONCLUSIONS: This meta-analysis demonstrated that experiencing AVHs is associated with increased activity in fronto-temporal areas involved in speech generation and speech perception, but also within the medial temporal lobe, a structure notably involved in verbal memory. Such findings support a model for AVHs in which aberrant cortical activations emerge within a distributed network involved at different levels of complexity in the brain architecture. Critical future directions are considered.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Our present study extends this by showing commonalities between many of the neural regions activated during AVH (such as left STG, left insula, left IFG) and those strongly activated during dialogic inner speech (Jardri et al., 2011; Kühn and Gallinat, 2012).”
From The brain's conversation with itself: neural substrates of dialogic inner speech (2016) · cites this paper as Jardri et al., 2011
In the citing paper
“Recent meta-analyses of symptom-capture studies have come to only partially overlapping conclusions: while Jardri et al. (2011) found AVHs to be associated with activation in left IFG, anterior insula, superior temporal, and hippocampal areas, Kühn and Gallinat (2012) could only find consistent results for bilateral IFG, postcentral gyrus, and parietal areas.”
From Inner Speech: Development, Cognitive Functions, Phenomenology, and Neurobiology (2015) · cites this paper as Jardri et al. (2011)
In the citing paper
“Increased activation within a bilateral frontotemporal network was confirmed by coordinate-based metaanalysis of the auditory hallucination (AH) state.27”
From Are hallucinations due to an imbalance between excitatory and inhibitory influences on the brain? (2016) · cites this paper as [27]
Citations
Cites
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
Thresholding of statistical maps in functional neuroimaging using the false discovery rate
Genovese, C. R., Lazar, N. A., & Nichols, T. (2002) · NeuroImage · doi:10.1006/nimg.2001.1037 · Cited by 4,923
Eickhoff, S. B., Laird, A. R., Grefkes, C., Wang, L. E., Zilles, K., & Fox, P. T. (2009) · Human Brain Mapping · doi:10.1002/hbm.20718 · Cited by 1,924
Perisylvian language networks of the human brain
Catani, M., Jones, D. K., & ffytche, D. H. (2005) · Annals of Neurology · doi:10.1002/ana.20319 · Cited by 1,832
Meta-analysis of the functional neuroanatomy of single-word reading: method and validation
Turkeltaub, P. E., Eden, G. F., Jones, K. M., & Zeffiro, T. A. (2002) · NeuroImage · doi:10.1006/nimg.2002.1131 · Cited by 1,604
Handedness and hemispheric language dominance in healthy humans
Knecht, S. (2000) · Brain · doi:10.1093/brain/123.12.2512 · Cited by 1,560
Bias between MNI and Talairach coordinates analyzed using the ICBM‐152 brain template
Lancaster, J. L., Tordesillas‐Gutiérrez, D., Martinez, M., Salinas, F., Evans, A., Zilles, K., Mazziotta, J. C., & Fox, P. T. (2007) · Human Brain Mapping · doi:10.1002/hbm.20345 · Cited by 1,464
Human Brain Language Areas Identified by Functional Magnetic Resonance Imaging
Binder, J. R., Frost, J. A., Hammeke, T. A., Cox, R. W., Rao, S. M., & Prieto, T. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00353.1997 · Cited by 1,424
A new brain region for coordinating speech articulation
Dronkers, N. F. (1996) · Nature · doi:10.1038/384159a0 · Cited by 1,192
A functional neuroanatomy of hallucinations in schizophrenia
Silbersweig, D. A., Stern, E., Frith, C., Cahill, C., Holmes, A., Grootoonk, S., Seaward, J., McKenna, P., Chua, S. E., Schnorr, L., et al. (1995) · Nature · doi:10.1038/378176a0 · Cited by 906
Flagged first, then by citations
Research works printed but not linked: 8
- Jardri R, 2009, Eur Arch Psychiatry Clin Neurosci, 259, 31
- Bentaleb LA, 2002, J Psychiatry Neurosci, 27, 110
- McGuire PK, 1996, Neuroreport, 7, 2095
- Stephane M, 2006, J Psychiatry Neurosci, 31, 396
- Kopecek M, 2007, Neuro Endocrinol Lett, 28, 53
- Talairach J , Tournoux P : A Coplanar Stereotactic Atlas of the -Human Brain. New York, Thieme Medical, 1988
- 10.1006/nimg.2002.1084 · DOI
- 10.1176/ajp.2007.164.3.467 · DOI
Cited by
Sorted by citations
Items 201–300 of 650
Auditory Hallucinations as Translational Psychiatry: Evidence from Magnetic Resonance Imaging
Hugdahl, K. (2017) · Balkan Medical Journal · doi:10.4274/balkanmedj.2017.1226 · Cited by 30
“From the “classic” studies by (11,13,15), which were mainly”
BackgroundZhang, X., Gao, J., Zhu, F., Wang, W., Fan, Y., Ma, Q., Ma, X., & Yang, J. (2018) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2018.01.002 · Cited by 34
Chen, C., Wang, H., Wu, S.-H., Huang, H., Zou, J.-L., Chen, J., Jiang, T., Zhou, Y., & Wang, G.-H. (2015) · Chinese Medical Journal · doi:10.4103/0366-6999.170269 · Cited by 37
“, decreased putamen DC) may result in mood and cognitive dysfunction in schizophrenia patients, which may lead to have difficulties to identify one’s own voice from an external source.[29,30] The abnormal putamen DC is not surprising; given previous evidence highlight that putamen contains rich dopaminergic neurons, t…”
ResultZhu, J., Wang, C., Liu, F., Qin, W., Li, J., & Zhuo, C. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00114 · Cited by 34
“…et al., 2013), cortical thickness (van Swam et al., 2012), white matter integrity (Geoffroy et al., 2014; Wigand et al., 2015), state activation (Jardri et al., 2011; Kompus et al., 2011; Allen et al., 2012; Kuhn and Gallinat, 2012), and resting-state functional connectivity (Hoffman and…”
BackgroundLooijestijn, J., Diederen, K. M. J., Goekoop, R., Sommer, I. E. C., Daalman, K., Kahn, R. S., Hoek, H. W., & Blom, J. D. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.02.004 · Cited by 31
“The established regions of activity were in conformity with prior fMRI studies on VAHs (Hoffman et al., 2007; Shergill et al., 2000; Jardri et al., 2011).”
Discovery and development of integrative biological markers for schizophrenia
Oertel‐Knöchel, V., Bittner, R. A., Knöchel, C., Prvulovic, D., & Hampel, H. J. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.05.006 · Cited by 33
“Disturbances of the hippocampus (Hall et al., 2008; Heckers, 2001; Ongur et al., 2006; Tregellas et al., 2009) and the superior temporal lobe (Crossley et al., 2009; Jardri et al., 2010; Oertel et al., 2010) appear to be the most robust findings.”
Oscillatory Cortical Network Involved in Auditory Verbal Hallucinations in Schizophrenia
van Lutterveld, R., Hillebrand, A., Diederen, K. M. J., Daalman, K., Kahn, R. S., Stam, C. J., & Sommer, I. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041149 · Cited by 32
Lavigne, K. M., & Woodward, T. S. (2017) · Human Brain Mapping · doi:10.1002/hbm.23934 · Cited by 32
“Although there is robust evidence that auditory and language networks are more active during hallucination-on than hallucination-off periods (Jardri et al., 2011), the trait-based literature is more equivocal.”
BackgroundA voice without a mouth no more: The neurobiology of language and consciousness
Skipper, J. I. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104772 · Cited by 31
“…traits, mood, wellbeing, mental health, and recovery from mental health problems (Al-Mosaiwi and Johnstone, 2018; D’Andrea et al., 2012; Fast and Funder, 2008; Luhmann, 2017; Pennebaker et al., 2014, 2003; Penzel et al., 2017; Pressman and Cohen, 2007; Robinson et al., 2013; Rude et al., 2004).”
Yan, C., Yang, T., Yu, Q., Jin, Z. H., Cheung, E. F. C., Liu, X., & Chan, R. C. K. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2015.01.001 · Cited by 33
“This threshold has been frequently used in previous studies (Li et al., 2010; Jardri et al., 2011; Sugranyes et al., 2011).”
Atagün, M. İ., Şıkoğlu, E. M., Can, S. S., Karakaş-Uğurlu, G., Ulusoy-Kaymak, S., Çayköylü, A., Algın, O., Phillips, M. L., Moore, C. M., & Öngür, D. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.11.012 · Cited by 33
“Moreover, left superior temporal cortices have been associated with symptom domains such as auditory hallucinations (Dierks et al., 1999; Jardri et al., 2011; Kuhn and Gallinat, 2012; Modinos et al., 2013; Shinn et al., 2013) and thought disorder (Seese et al.”
BackgroundHjelmervik, H., Craven, A., Sinceviciute, I., Johnsen, E., Kompus, K., Bless, J., Kroken, R., Løberg, E., Ersland, L., Grüner, R., et al. (2019) · Schizophrenia bulletin · doi:10.1093/schbul/sbz099 · Cited by 33
““hearing a voice,” in the absence of an external auditory source.(1,2) Neuronal underpinnings of AVHs are to date”
BackgroundCommon and distinct brain networks of autoscopic phenomena
Blondiaux, E., Heydrich, L., & Blanke, O. (2021) · NeuroImage Clinical · doi:10.1016/j.nicl.2021.102612 · Cited by 35
“…also been involved in inner speech and language processing (Morin and Michaud, 2007; McGuire et al., 1996; Shergill et al., 2001; Geva et al., 2011; Liakakis et al., 2011; Hubl et al., 2004) and in auditory verbal hallucinations, based on functional connectivity work in patients with such…”
Schülke, R., & Straube, B. (2018) · Schizophrenia Bulletin · doi:10.1093/schbul/sby144 · Cited by 31
Moseley, P., Alderson-Day, B., Common, S., Dodgson, G., Lee, R., Mitrenga, K., Moffatt, J., & Fernyhough, C. (2022) · Clinical Psychological Science · doi:10.1177/21677026211059802 · Cited by 30
“…speech priors (e.g., Corlett et al., 2019) and with neuroimaging studies showing activation in brain areas associated with auditory perception (Jardri et al., 2011), although more work is required to understand which aspects of this task drive the association (e.g., verbal imagery; Moseley et…”
Moseley, P., Alderson‐Day, B., Ellison, A., Jardri, R., & Fernyhough, C. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00515 · Cited by 31
“Evidence from cognitive neuroscience suggests that AVHs are accompanied by high levels of activation in, among other areas, the superior temporal gyrus, particularly in the left hemisphere (Allen et al., 2008; Jardri et al., 2011).”
BackgroundResultSelf-citationAnodal tDCS targeting the left temporo-parietal junction disrupts verbal reality-monitoring
Mondino, M., Poulet, E., Suaud‐Chagny, M., & Brunelin, J. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2016.07.022 · Cited by 35
Improving treatments for psychotic disorders: beyond cognitive behaviour therapy for psychosis
Nelson, B., Torregrossa, L. J., Thompson, A. D., Sass, L. A., Park, S., Hartmann, J., McGorry, P. D., & Álvarez‐Jiménez, M. (2020) · Psychosis · doi:10.1080/17522439.2020.1742200 · Cited by 30
“The efficacy of CBT may be enhanced if applied during symptom activation (referred to as a “symptom capture” approach (Jardri et al., 2011)), i.”
BackgroundBenster, L. L., Weissman, C. R., Stolz, L. A., Daskalakis, Z. J., & Appelbaum, L. G. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02673-2 · Cited by 32
“Evidence suggests abnormal hyper-connectivity between the dorsal lateral prefrontal cortex (DLPFC) and the temporal parietal junction (TPJ) may be implicated in the experience of auditory hallucinations [36, 37].”
BackgroundLeroux, E., Delcroix, N., & Dollfus, S. (2016) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2016.1274053 · Cited by 29
“The AF is a key anatomical connection between the frontal and temporo-parietal speech areas (Jardri et al. 2011) and is involved in particular in phonological language processing (CurcicBlake et al.”
BackgroundAltered temporal, but intact spatial, features of transient network dynamics in psychosis
Wang, D., Peng, X., Pelletier‐Baldelli, A., Orlov, N. D., Farabaugh, A. H., Nasr, S., Eryilmaz, H., D, M. F. M., Holmes, A. J., Roffman, J. L., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-020-00983-1 · Cited by 31
Yun, J., Kim, S. N., Lee, T. Y., Chon, M., & Kwon, J. S. (2015) · Human Brain Mapping · doi:10.1002/hbm.23083 · Cited by 29
“…are experienced by 60–70% of subjects with schizophrenia [Andreasen and Flaum, 1991; Cachia et al., 2015], may be characterized as false perceptions of sounds including words, whole sentences, or entire conversations in the absence of an identifiable, external stimulus [Jardri et al., 2011, 2013].”
BackgroundInfluentialStructured Sparse Principal Components Analysis With the TV-Elastic Net Penalty
de Pierrefeu, A., Löfstedt, T., Hadj‐Selem, F., Dubois, M., Jardri, R., Fovet, T., Ciuciu, P., Frouin, V., & Duchesnay, É. (2017) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2017.2749140 · Cited by 30
Self-citationNathou, C., Etard, O., & Dollfus, S. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s168801 · Cited by 28
“a language-related network associating the left and upper temporal, precentral and supramarginal temporal gyri, the Broca area, the anterior insula and the frontal operculum bilaterally.(7) Other teams compared the functional imaging”
BackgroundAbnormal dynamic resting-state brain network organization in auditory verbal hallucination
Geng, H., Xu, P., Sommer, I. E., Luo, Y., Aleman, A., & Ćurĉić‐Blake, B. (2020) · Brain Structure and Function · doi:10.1007/s00429-020-02119-1 · Cited by 27
Decoding Activity in Broca's Area Predicts the Occurrence of Auditory Hallucinations Across Subjects
Fovet, T., Yger, P., Lopes, R., de Pierrefeu, A., Duchesnay, É., Houenou, J., Thomas, P., Szaffarczyk, S., Domenech, P., & Jardri, R. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.08.024 · Cited by 28
Self-citationSteinmann, S., Amselberg, R., Cheng, B., Thomalla, G., Engel, A. K., Leicht, G., & Mulert, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-33586-6 · Cited by 30
Ffytche, D. H., & Wible, C. G. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu041 · Cited by 27
Jensen, K. M., Calhoun, V. D., Fu, Z., Yang, K., Faria, A. V., Ishizuka, K., Sawa, A., Andrés-Camazón, P., Coffman, B. A., Seebold, D., et al. (2024) · NeuroImage Clinical · doi:10.1016/j.nicl.2024.103584 · Cited by 25
“Both of these regions are involved in the language network, and as a result, many studies have investigated and identified associations between the IFG, STG, and auditory verbal hallucinations (Jardri et al., 2011; Kompus et al., 2011; Kuhn & Gallinat, 2012; Zhang et al., 2015).”
BackgroundHerold, C. J. (2015) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00053 · Cited by 28
Brain‐based ranking of cognitive domains to predict schizophrenia
Karrer, T. M., Bassett, D. S., Derntl, B., Gruber, O., Aleman, A., Jardri, R., Laird, A. R., Fox, P. T., Eickhoff, S. B., Grisel, O., et al. (2019) · Human Brain Mapping · doi:10.1002/hbm.24716 · Cited by 26
“, 2013) and (ii) functional investigations have reported increased neural activity in areas related to speech perception, language, and memory during active sensations of speech hallucinations (Allen et al., 2012; Jardri et al., 2011).”
BackgroundSelf-citationDelavari, F., Sandini, C., Zöller, D., Mancini, V., Bortolin, K., Schneider, M., Ville, D. V. D., & Eliez, S. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.12.033 · Cited by 30
Asai, T., & Tanno, Y. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.09.055 · Cited by 28
“These studies have been followed up by meta-analysis (Jardri et al., 2011b).”
BackgroundMethodMennigen, E., Fryer, S. L., Rashid, B., Damaraju, E., Du, Y., Loewy, R. L., Stuart, B. K., Calhoun, V. D., & Mathalon, D. H. (2018) · Brain Connectivity · doi:10.1089/brain.2018.0579 · Cited by 26
“Both regions, STG and left TPJ, have been found to be associated with dysconnectivity in schizophrenia patients experiencing AUD verbal hallucinations (Alderson-Day et al., 2015; Jardri et al., 2011; Thoma et al., 2016; Vercammen et al., 2010).”
BackgroundHan, W., Sorg, C., Zheng, C., Yang, Q., Zhang, X., Ternblom, A., Mawuli, C. B., Gao, L., Luo, C., Yao, D., et al. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101725 · Cited by 27
“The strongly affected regions in language-related areas (Broca's area and the inferior parietal lobule), as well as the anterior insula seemed to be reasonable, since a recent metaanalysis concluded that the auditory hallucinations in schizophrenia patients is associated with aberrant activity bilaterally in those reg…”
Neurological Soft Signs Predict Auditory Verbal Hallucinations in Patients With Schizophrenia
Wolf, R. C., Rashidi, M., Schmitgen, M. M., Fritze, S., Sambataro, F., Kubera, K. M., & Hirjak, D. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa146 · Cited by 27
Cui, L., Chen, G., Xu, Z., Liu, L., Wang, H., Guo, L., Liu, W.-M., Liu, T., Qi, S., Liu, K., et al. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.12.006 · Cited by 26
Deviations in early hippocampus development contribute to visual hallucinations in schizophrenia
Cachia, A., Cury, C., Brunelin, J., Plaze, M., Delmaire, C., Oppenheim, C., Medjkane, F., Thomas, P., & Jardri, R. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0779-9 · Cited by 26
“This interpretation supports and extends previous fi ndings in A + VH patients found to have abnormal sulca-tion 22 , another marker of prenatal brain deviation 24 . and decreased sulcation were also reported 46,47 , but the present IHI fi ndings provide the fi rst evidence that the vulnerability period for A + VH preced…”
BackgroundInfluentialSelf-citationKubera, K. M., Thomann, P. A., Hirjak, D., Barth, A., Sambataro, F., Vasić, N., Wolf, N. D., Frasch, K., & Wolf, R. C. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.12.009 · Cited by 29
Gupta, T., Kelley, N. J., Pelletier‐Baldelli, A., & Mittal, V. A. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00094 · Cited by 28
Hallucinations, neuroplasticity, and prediction errors in schizophrenia
McCleery, A., Wynn, J. K., & Green, M. F. (2018) · Scandinavian Journal of Psychology · doi:10.1111/sjop.12413 · Cited by 25
fMRI capture of auditory hallucinations: Validation of the two‐steps method
Leroy, A., Foucher, J., Pins, D., Delmaire, C., Thomas, P., Roser, M. M., Lefebvre, S., Amad, A., Fovet, T., Jaafari, N., et al. (2017) · Human Brain Mapping · doi:10.1002/hbm.23707 · Cited by 25
“The overlap was maximal within the ASCs; these areas, including the insula and temporo-parietal junction, are known to play a core role in AVH experiences (Jardri et al., 2011).”
BackgroundResultInfluentialSelf-citationde Pierrefeu, A., Fovet, T., Hadj‐Selem, F., Löfstedt, T., Ciuciu, P., Lefebvre, S., Thomas, P., Lopes, R., Jardri, R., & Duchesnay, É. (2018) · Human Brain Mapping · doi:10.1002/hbm.23953 · Cited by 25
“…in these regions, especially the insula and the right homologue of Broca ’ s area, is associated with the occurrence of auditory hallucinations (Jardri et al., 2011; Sommer et al., 2008), whereas language production in a natural context predominantly activates left-lateralized frontal and…”
BackgroundInfluentialSelf-citationChang, X., Zhao, W. D., Kang, J., Xiang, S., Xie, C., Hernández, H. C., Palaniyappan, L. K., & Feng, J. (2022) · Schizophrenia · doi:10.1038/s41537-022-00308-x · Cited by 31
Perez, D. L., Pan, H., Weisholtz, D. S., Root, J. C., Tüscher, O., Fischer, D. B., Butler, T., Vago, D. R., Isenberg, N., Epstein, J., et al. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2015.06.002 · Cited by 25
“While the neural basis of auditory hallucinations in schizophrenia has been extensively investigated (Silbersweig et al., 1995; Silbersweig and Stern, 1996; Epstein et al., 1999; Lennox et al., 2000; Raij et al., 2009; Jardri et al., 2011), the neurobiology of delusions has not been so well characterized.”
BackgroundPerisylvian GABA levels in schizophrenia and bipolar disorder
Atagün, M. İ., Şıkoğlu, E. M., Soykan, Ç., Süleyman, C. S., Ulusoy-Kaymak, S., Çayköylü, A., Algın, O., Phillips, M. L., Öngür, D., & Moore, C. M. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.11.051 · Cited by 26
Insights into hallucinations in schizophrenia: Novel treatment approaches
Aleman, A., & Larøi, F. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.90 · Cited by 24
The neural signature of reality‐monitoring: A meta‐analysis of functional neuroimaging studies
Lavallé, L., Brunelin, J., Jardri, R., Haesebaert, F., & Mondino, M. (2023) · Human Brain Mapping · doi:10.1002/hbm.26387 · Cited by 24
Self-citationGao, S., Lu, S., Shi, X., Ming, Y., Xiao, C., Sun, J., Yao, H. Q., & Xu, X. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00282 · Cited by 24
Xie, Y., Hé, Y., Guan, M., Wang, Z., Zhou, G., Ma, Z., Wang, H., & Yin, H. J. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114393 · Cited by 24
Hugdahl, K., Craven, A. R., Johnsen, E., Ersland, L., Stoyanov, D., Kandilarova, S., Sandøy, L. B., Kroken, R. A., Løberg, E., & Sommer, I. E. (2022) · Schizophrenia Bulletin · doi:10.1093/schbul/sbac028 · Cited by 26
“The block-analysis revealed that the activated ROIs showed large overlaps with the activated ROIs reported in the Jardri et al. 11 and Kompus et al. 13 meta-analyses.”
InfluentialPaul, A. K., Bose, A., Kalmady, S. V., Shivakumar, V., Sreeraj, V. S., Parlikar, R. U., Narayanaswamy, J. C., Dursun, S. M., Greenshaw, A. J., Greiner, R., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.923938 · Cited by 24
“The role of the insula in AVH pathophysiology has been well established in the literature (42, 72).”
BackgroundThe rise of large-scale imaging studies in psychiatry
Turner, J. A. (2014) · GigaScience · doi:10.1186/2047-217x-3-29 · Cited by 25
“To ascertain where in the brain functional MRI (fMRI) signal changes are related to different conditions in a simple cognitive task, 10–15 subjects may be sufficient; studies of the neural correlates of auditory hallucinations in psychotic populations have largely pulled from smaller samples of 1–10 [6], though larger…”
BackgroundThoma, R., Chaze, C., Lewine, J., Calhoun, V., Clark, V., Bustillo, J., Houck, J., Ford, J., Bigelow, R., Wilhelmi, C., et al. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00039 · Cited by 26
Walter, A., Suenderhauf, C., Smieskova, R., Lenz, C., Harrisberger, F., Schmidt, A., Vogel, T., Lang, U. E., Riecher‐Rössler, A., Eckert, A., et al. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00189 · Cited by 24
Mondino, M., Sauvanaud, F., & Brunelin, J. (2018) · Journal of Ect · doi:10.1097/yct.0000000000000525 · Cited by 24
Xie, S., Liu, B., Wang, J., Zhou, Y., Cui, Y. J., Song, M., Chen, Y., Li, P., Lü, L., Lv, L., et al. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.12.024 · Cited by 23
Jung, S., Lee, A., Bang, M., & Lee, S. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.102022 · Cited by 23
“Our finding of an inverse association between left FG volume and AVH severity is consistent with previous investigations showing that aberrant semantic top-down processing affects the experience of AVHs (Vercammen and Aleman, 2010; Daalman et al., 2012).”
InfluentialHumpston, C. S., Garrison, J. R., Orlov, N. D., Aleman, A., Jardri, R., Fernyhough, C., & Allen, P. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa103 · Cited by 23
Self-citationRecent findings on neurofeedback training for auditory hallucinations in schizophrenia
Hirano, Y., & Tamura, S. (2021) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000693 · Cited by 18
Brandt, S. J., Oral, H. Y., Arellano-Bravo, C., Plawecki, M. H., Hummer, T. A., & Francis, M. (2021) · Neurotherapeutics · doi:10.1007/s13311-021-01046-1 · Cited by 23
Mehta, D. D., Siddiqui, S., Ward, H. B., Steele, V. R., Pearlson, G. D., & George, T. P. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.03.016 · Cited by 23
Fovet, T., Orlov, N. D., Dyck, M., Allen, P., Mathiak, K., & Jardri, R. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00103 · Cited by 25
“State Studies Functional brain imaging suggests that a distributed network of brain regions underlies the experience of AVHs (84).”
BackgroundResultSelf-citationZhuo, C.-J., Zhu, J.-J., Wang, C.-L., Wang, L.-N., Li, J., & Qin, W. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.178974 · Cited by 22
Cheng Ann, C. H. E. N., Wang, G., Wu, S., Zou, J., Zhou, Y., & Wang, H. (2020) · Current Medical Science · doi:10.1007/s11596-020-2271-4 · Cited by 22
Dissociation as a trauma-related phenomenon.
Brand, B. L., & Frewen, P. (2017) · American Psychological Association eBooks · doi:10.1037/0000019-013 · Cited by 23
Gray Matter Changes in the Insular Cortex During the Course of the Schizophrenia Spectrum
Takahashi, T., Kido, M., Sasabayashi, D., Nakamura, M., Furuichi, A., Takayanagi, Y., Noguchi, K., & Suzuki, M. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00659 · Cited by 21
The Etiology of Auditory Hallucinations in Schizophrenia: From Multidimensional Levels
Shao, X., Liao, Y., Gu, L., Chen, W., & Tang, J. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.755870 · Cited by 21
“Across populations of schizophreniaspectrum disorder, psychotic disorder, and healthy controls, meta-analyses of trait studies revealed that AVHs were frequently related to activations in the left middle and superior temporal gyrus, left postcentral and precentral gyrus, left insula, left hippocampus/parahippocampal r…”
BackgroundTyagi, P., Dhyani, M., Khattri, S., Tejan, V., Tikka, S. K., & Garg, S. (2022) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2022.103176 · Cited by 21
Xie, Y.-J., Guan, M.-Z., Cai, Y., Wang, Z.-H., Ma, Z.-J., Fang, P., & Wang, H.-N. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114974 · Cited by 20
Neurocognitive Basis of Schizophrenia: Information Processing Abnormalities and Clues for Treatment
Aleman, A. (2014) · Advances in Neuroscience · doi:10.1155/2014/104920 · Cited by 21
“Two meta-analyses have summarized the brain activation studies on hallucination-related activation during scanning [41, 42].”
BackgroundChatterjee, I. (2018) · F1000Research · doi:10.12688/f1000research.16405.1 · Cited by 21
Investigating the roles of medial prefrontal and superior temporal cortex in source monitoring
Moseley, P., Mitrenga, K. J., Ellison, A., & Fernyhough, C. (2018) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2018.10.001 · Cited by 23
Auditory verbal hallucination and the auditory network: From molecules to connectivity
Huang, J., Zhuo, C., Xu, Y. J., & Lin, X. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.04.051 · Cited by 21
During day and night: Childhood psychotic experiences and objective and subjective sleep problems
Koopman‐Verhoeff, M. E., Bolhuis, K., Cecil, C. A. M., Kocevska, D., Hudziak, J. J., Hillegers, M. H. J., Mileva‐Seitz, V. R., Reiss, I. K. M., Duijts, L., Verhulst, F. C., et al. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.12.002 · Cited by 27
Auditory Hallucinations: Debunking the Myth of Language Supremacy
Waters, F., & Jardri, R. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu166 · Cited by 21
Self-citationModern neuroimaging in psychiatry: Towards the integration of functional and molecular information
Linden, D. E. J., & Thome, J. (2011) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.598713 · Cited by 21
de Boer, J. N., Heringa, S. M., van Dellen, E., Wijnen, F. N. K., & Sommer, I. E. (2016) · Brain and Language · doi:10.1016/j.bandl.2016.07.011 · Cited by 20
Behrendt, R. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.07.009 · Cited by 20
Thomas, F., Moulier, V., Valero‐Cabré, A., & Januel, D. (2016) · Revue Neurologique · doi:10.1016/j.neurol.2016.09.001 · Cited by 21
Association of cognitive and P50 suppression deficits in chronic patients with schizophrenia.
Xia, L., Wang, D.-M., Wang, J.-S., Xu, H., Huo, L., Tian, Y., Dai, Q., Wei, S.-C., Wang, W., Zhang, G.-Y., et al. (2020) · Clinical Neurophysiology · doi:10.1016/j.clinph.2019.12.405 · Cited by 17
Yanagi, M., Hosomi, F., Kawakubo, Y., Tsuchiya, A., Ozaki, S., & Shirakawa, O. (2020) · Scientific Reports · doi:10.1038/s41598-020-66560-2 · Cited by 20
Reconciling competing mechanisms posited to underlie auditory verbal hallucinations
Thakkar, K. N., Mathalon, D. H., & Ford, J. M. (2020) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0702 · Cited by 21
Wei, Y., Wang, J., Yan, C., Li, Z.-Q., Pan, X., Cui, Y., Su, T., Liu, T., & Tang, Y. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.176983 · Cited by 24
“This threshold has been used in former ALE analyses.[41,42] Significant clusters were overlaid onto an anatomical Talairach template, colin_tlrc_1 × 1 × 1.”
MethodMondino, M., Fonteneau, C., Simon, L., Dondé, C., Haesebaert, F., Poulet, E., & Brunelin, J. (2020) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-020-01149-4 · Cited by 19
Default mode network alterations underlie auditory verbal hallucinations in schizophrenia
Marino, M., Spironelli, C., Mantini, D., Craven, A. R., Ersland, L., Angrilli, A., & Hugdahl, K. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.08.006 · Cited by 21
Investigating Brain Connectivity with Graph Neural Networks and GNNExplainer
Zhdanov, M., Steinmann, S., & Hoffmann, N. (2022) · Proceedings - International Conference on Pattern Recognition/Proceedings/International Conference on Pattern Recognition · doi:10.1109/icpr56361.2022.9956201 · Cited by 19
“recent findings [5], [6], the substantial similarity between the hallucinations and real voices is connected to alterations in a brain network related to speech and language processing.”
BackgroundHumpston, C. S., & Woodward, T. S. (2024) · The Lancet Psychiatry · doi:10.1016/s2215-0366(24)00061-0 · Cited by 19
When soft voices die: auditory verbal hallucinations and a four letter word (love)
McCarthy‐Jones, S., & Davidson, L. (2012) · Mental Health Religion & Culture · doi:10.1080/13674676.2012.674498 · Cited by 19
Cortical salience network activation precedes the development of delusion severity
Raij, T. T., Mäntylä, T. J. S., Mantere, O., Kieseppä, T., & Suvisaari, J. (2016) · Psychological Medicine · doi:10.1017/s0033291716001057 · Cited by 20
“…core of CSN, and an association between psychotic symptoms and CSN were found in previous cross-sectional studies (Crespo-Facorro et al. 2000; Koutsouleris et al. 2008; Cascella et al. 2011; Gradin et al. 2011; Jardri et al. 2011; Menon et al. 2011; Palaniyappan et al. 2011; Radaelli et al. 2014).”
ResultPsomiades, M., Mondino, M., Fonteneau, C., Bation, R., Haesebaert, F., Suaud‐Chagny, M., & Brunelin, J. (2018) · Scientific Reports · doi:10.1038/s41598-018-22597-y · Cited by 19
Lee, W. H., Kennedy, N. I., Bikson, M., & Frangou, S. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00048 · Cited by 21
“We identified six meta-analyses that examined structural (40, 41) and functional differences in patients with AVH compared to healthy individuals (42–45).”
BackgroundChen, J.-L., Xue, K.-K., Yang, M., Wang, K.-F., Xu, Y.-H., Wen, B.-H., Cheng, J.-L., Han, S.-Q., & Wei, Y.-R. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.821078 · Cited by 15
“Defined as the auditory experience of “hearing voices” in the absence of external stimuli that cause them, AVH is suffered by 60–80% of the patients and often produces distress, functional disability, and behavioral alterations (Jardri et al., 2011; Hjelmervik et al., 2020).”
BackgroundXie, Y.-J., Guan, M.-Z., He, Y., Wang, Z.-H., Ma, Z.-J., Fang, P., & Wang, H.-N. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1071769 · Cited by 20
Visual Hallucinations in Psychosis: The Curious Absence of the Primary Visual Cortex
van Ommen, M. M., van Laar, T., Renken, R. J., Cornelissen, F. W., & Bruggeman, R. (2023) · Schizophrenia Bulletin · doi:10.1093/schbul/sbac140 · Cited by 18
Meta-analysis of structural and functional brain abnormalities in early-onset schizophrenia
Wang, L., Liu, R., Liao, J., Xiong, X., Xia, L., Wang, W., Liu, J., Zhao, F., Zhuo, L., & Li, H. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1465758 · Cited by 18
Moran, M., Weisinger, B., Ludovici, K., McAdams, H. M., GREENSTEIN, D. K., Gochman, P., Miller, R., CLASEN, L. S., Rapoport, J. L., & Gogtay, N. (2013) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2013.05.010 · Cited by 18
“Recent metaanalyses have even pointed out that the insula is a common site of cortical activation during auditory verbal hallucinations (Jardri et al., 2011).”
BackgroundAuditory verbal hallucinations reflect stable auditory attention deficits: a prospective study
Løberg, E., Jørgensen, H. A., Kroken, R., & Johnsen, E. (2015) · Cognitive Neuropsychiatry · doi:10.1080/13546805.2014.977857 · Cited by 18
Zhuo, C., Xiao, B., Chen, C., Jiang, D., Li, G., Ma, X., Li, R., Wang, L., Xu, Y. J., Zhou, C., et al. (2020) · Brain and Behavior · doi:10.1002/brb3.1611 · Cited by 18
Wang, Q., Ren, H., Li, C., Li, Z., Li, J., Li, H., Dai, L., Dong, M., Zhou, J., He, J., et al. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01866-5 · Cited by 18
Metadata
- Authors
- Jardri, R., Pouchet, A., Pins, D., & Thomas, P.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Venue
- American Journal of Psychiatry
- Published
- 2011-01
- Volume
- 168
- Issue
- 1
- Pages
- 73-81
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2142837020
- Cited by
- 651
- References
- 99
- Citations by year
- 2026: 25 · 2025: 34 · 2024: 31 · 2023: 26 · 2022: 42 · 2021: 43 · 2020: 50 · 2019: 51 · 2018: 50 · 2017: 36 · 2016: 54 · 2015: 30 · 2014: 43 · 2013: 38 · 2012: 72
- FWCI
- 3.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Keywords
- auditory verbal hallucinations, schizophrenia, schizophrenia spectrum disorders, cortical activation, activation likelihood estimation, Broca's area, anterior insula, frontal operculum, temporal lobe, hippocampus, parahippocampal region, speech generation, speech perception, verbal memory, fronto-temporal network, medial temporal lobe
- MeSH terms
- Brain Mapping, Cerebral Cortex, Hallucinations, Humans, Magnetic Resonance Imaging, Schizophrenia, Schizophrenic Psychology, Positron-Emission Tomography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
