Web-based interventions for comorbid depression and chronic illness: a systematic review
Abstract
Summary Web-based interventions offer potential benefits for managing and treating depression in the context of chronic physical illness, however their use with this population has yet to be quantitatively assessed. The present systematic review examined the biopsychosocial data from 11 independent studies ( N = 1348 participants), including randomised controlled and quasi-experimental designs most commonly performed with diabetes and multiple sclerosis. Study quality was evaluated using the Downs and Black (1998) index, with most studies being statistically underpowered although internal validity was demonstrated. Treatment outcomes were quantified using Cohen’s d effect sizes. Results indicated significant short-term improvements in depression severity ( d w = 0.36, CI = 0.20-0.52, p < 0.01), in addition to quality of life, problem-solving skills, functional ability, anxiety and pain-related cognitions ( d range = 0.23 to 1.10). Longer-term outcomes could not be determined based on the limited data. Further robust studies are required before wider adoption of web techniques takes place.
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Recent systematic reviews suggest that promising results can be obtained from web-based interventions for adults with chronic illnesses and depression.
“In addition, recent systematic reviews suggest that promising results can be obtained from web-based interventions for adults with chronic illnesses and depression.25–27”
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Mohammed, J. D., Agbana, O. F., & Doe, V. A. (2025) · Howard Journal of Communications · doi:10.1080/10646175.2025.2531213
- Authors
- Charova, E., Dorstyn, D., Tully, P., & Mittag, O.
- Affiliations
- The University of Adelaide (AU)
- University of Freiburg (DE)
- Corresponding author
- Dorstyn, Diana
- Venue
- Journal of Telemedicine and Telecare
- Publisher
- SAGE Publications
- Published
- 2015-02-22
- Volume
- 21
- Issue
- 4
- Pages
- 189-201
- ISSN
- 1357-633X (ISSN-L)
- 1758-1109
- OpenAlex
- W2154688113
- Cited by
- 30
- References
- 69
- Citations by year
- 2025: 3 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 1 · 2019: 2 · 2018: 5 · 2017: 1 · 2016: 8
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Telemedicine and Telecare (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Figshare (submittedVersion)
- FreiDok plus (Universitätsbibliothek Freiburg) (submittedVersion)
- RUNE (Research UNE) (submittedVersion)
- Funders
- National Health and Medical Research Council
- National Medical Research Council
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Keywords
- online intervention, online therapy, comorbid depression, chronic physical illness, diabetes mellitus, multiple sclerosis, depression severity, quality of life, problem-solving skills, functional capacity, anxiety, pain-related cognitions, biopsychosocial model
- MeSH terms
- Anxiety, Chronic Disease, Cognition, Depressive Disorder, Humans, Problem Solving, Psychotherapy, Quality of Life, Comorbidity, Telemedicine, Internet
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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