Mitochondrial and sex steroid hormone crosstalk during aging

Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men

Harman, S. M., Metter, E. J., Tobin, J. D., Pearson, J., & Blackman, M. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7219 · Cited by 2,760 · see citing works

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Trifunovic, A., Wredenberg, A., Falkenberg, M., Spelbrink, J. N., Rovio, A. T., Bruder, C. E., Bohlooly-Y, M., Gidlöf, S., Oldfors, A., Wibom, R., et al. (2004) · Nature · doi:10.1038/nature02517 · Cited by 2,734 · see citing works

The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

Miller, W. L., & Auchus, R. J. (2011) · Endocrine Reviews · doi:10.1210/er.2010-0013 · Cited by 2,458 · cited 3× · see citing works

Oxidative damage and mitochondrial decay in aging.

Shigenaga, M. K., Hagen, T. M., & Ames, B. N. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.23.10771 · Cited by 2,055 · see citing works

Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging Study

Feldman, H. A., Longcope, C., Derby, C. A., Johannes, C. B., Araujo, A. B., Coviello, A. D., Bremner, W. J., & McKinlay, J. B. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.2.8201 · Cited by 1,861 · see citing works

Initial and cyclic recruitment of ovarian follicles

McGee, E. A., & Hsueh, A. J. W. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.2.0394 · Cited by 1,771 · see citing works

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men

Bhasin, S., Storer, T. W., Berman, N., Callegari, C., Clevenger, B., Phillips, J., Bunnell, T. J., Tricker, R., Shirazi, A., & Casaburi, R. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607043350101 · Cited by 1,659 · see citing works

Identification of late-onset hypogonadism in middle-aged and elderly men

Wu, F. C. W., Tajar, A., Beynon, J. M., Pye, S. R., Silman, A. J., Finn, J. D., O'Neill, T. W., Bartfai, G., Casanueva, F. F., Forti, G., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0911101 · Cited by 1,544 · see citing works

Human Ovarian Reserve from Conception to the MenopausePreprint

Wallace, W. H., & Kelsey, T. (2009) · Nature Precedings · doi:10.1371/journal.pone.0008772 · Cited by 884 · see citing works

Follicular Depletion During the Menopausal Transition: Evidence for Accelerated Loss and Ultimate Exhaustion*

Richardson, S. J., Senikas, V., & Nelson, J. F. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-65-6-1231 · Cited by 714 · see citing works

Postmenopausal Hormone Therapy: An Endocrine Society Scientific Statement

Santen, R. J., Allred, D. C., Ardoin, S. P., Archer, D. F., Boyd, N. F., Braunstein, G. D., Burger, H., Colditz, G. A., Davis, S. R., Gambacciani, M., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2509 · Cited by 679 · see citing works

Effects of Testosterone on Muscle Strength, Physical Function, Body Composition, and Quality of Life in Intermediate-Frail and Frail Elderly Men: A Randomized, Double-Blind, Placebo-Controlled Study

Srinivas-Shankar, U., Roberts, S. A., Connolly, M. J., O'Connell, M. D. L., Adams, J. E., Oldham, J. A., & Wu, F. C. W. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1251 · Cited by 629 · see citing works

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

Quinlan, C. L., Perevoshchikova, I. V., Hey‐Mogensen, M., Orr, A. L., & Brand, M. D. (2013) · Redox Biology · doi:10.1016/j.redox.2013.04.005 · Cited by 595 · see citing works

The Menopausal Transition: Analysis of LH, FSH, Estradiol, and Progesterone Concentrations During Menstrual Cycles of Older Women

Sherman, B. M., West, J. H., & Korenman, S. G. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-42-4-629 · Cited by 583 · see citing works

Effect of Testosterone Treatment on Body Composition and Muscle Strength in Men Over 65 Years of Age

Snyder, P. J. (1999) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.8.2647 · Cited by 531 · see citing works

Testosterone administration to older men improves muscle function: molecular and physiological mechanisms

Ferrando, A. A., Sheffield-Moore, M., Yeckel, C. W., Gilkison, C., Jiang, J., Achacosa, A., Lieberman, S. A., Tipton, K., Wolfe, R. R., & Urban, R. J. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00362.2001 · Cited by 522 · see citing works

Theca: the forgotten cell of the ovarian follicle

Young, J. M., & McNeilly, A. S. (2010) · Reproduction · doi:10.1530/rep-10-0094 · Cited by 516 · see citing works

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

Van Raamsdonk, J. M., & Hekimi, S. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000361 · Cited by 511 · see citing works

Mitochondrial localization of estrogen receptor β

Yang, S.-H., Liu, R., Perez, E., Wen, Y., Stevens, S. M., Valencia, T. G., Brun‐Zinkernagel, A., Prókai, L., Will, Y., Dykens, J. A., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306948101 · Cited by 501 · see citing works

Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men

NEAVES, W. B., JOHNSON, L., PORTER, J. C., PARKER, C. R., & PETTY, C. S. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-4-756 · Cited by 495 · see citing works

Steroid hormone synthesis in mitochondria

Miller, W. L. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.04.014 · Cited by 479 · see citing works

Hormone Therapy and Coronary Heart Disease: The Role of Time since Menopause and Age at Hormone Initiation

Grodstein, F., Manson, J. E., & Stampfer, M. J. (2006) · Journal of Women s Health · doi:10.1089/jwh.2006.15.35 · Cited by 475 · see citing works

Sex hormones and age: A cross-sectional study of testosterone and estradiol and their bioavailable fractions in community-dwelling men

Ferrini, R. L., & Barrett-Connor, E. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009519 · Cited by 473 · see citing works

Relationship Between Testosterone Levels, Insulin Sensitivity, and Mitochondrial Function in Men

Pitteloud, N., Mootha, V. K., Dwyer, A. A., Hardin, M., Lee, H., Eriksson, K.-F., Tripathy, D., Yialamas, M., Groop, L., Elahi, D., et al. (2005) · Diabetes Care · doi:10.2337/diacare.28.7.1636 · Cited by 472 · see citing works

Age at Menopause, Cause-Specific Mortality and Total Life Expectancy

Ossewaarde, M. E., Bots, M. L., Verbeek, A. L. M., Peeters, P. H. M., van der Graaf, Y., Grobbee, D. E., & van der Schouw, Y. T. (2005) · Epidemiology · doi:10.1097/01.ede.0000165392.35273.d4 · Cited by 443 · see citing works

Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase

Hagen, T. M., Yowe, D. L., Bartholomew, J. C., Wehr, C. M., Katherine, L. B. B., Park, J.-Y., & Ames, B. N. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.3064 · Cited by 434 · see citing works

Ultrastructural localization of estrogen receptor β immunoreactivity in the rat hippocampal formation

Milner, T. A., Ayoola, K., Drake, C. T., Herrick, S. P., Tabori, N. E., McEwen, B. S., Mitra, S. W., & Alves, S. E. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20724 · Cited by 358 · see citing works

Reactive Oxygen Disrupts Mitochondria in MA-10 Tumor Leydig Cells and Inhibits Steroidogenic Acute Regulatory (StAR) Protein and Steroidogenesis

Thorsten Diemer, A., Allen, J., Hales, K. H., & Hales, D. B. (2003) · Endocrinology · doi:10.1210/en.2002-0090 · Cited by 356 · see citing works

Superoxide dismutase is dispensable for normal animal lifespan

Raamsdonk, J. M. V., & Hekimi, S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1116158109 · Cited by 334 · see citing works

Minireview: Regulation of Steroidogenesis by Electron Transfer

Miller, W. L. (2005) · Endocrinology · doi:10.1210/en.2005-0096 · Cited by 324 · cited 1× · see citing works

Estrogen Increases Mitochondrial Efficiency and Reduces Oxidative Stress in Cerebral Blood Vessels

Stirone, C., Duckles, S. P., Krause, D. N., & Procaccio, V. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.014662 · Cited by 315 · see citing works

Progesterone and Estrogen Regulate Oxidative Metabolism in Brain Mitochondria

Irwin, R. W., Yao, J., Hamilton, R. T., Cadenas, E., Brinton, R. D., & Nilsen, J. (2008) · Endocrinology · doi:10.1210/en.2007-1227 · Cited by 289 · see citing works

The Free Radical Theory of Aging Is Dead. Long Live the Damage Theory!

Gladyshev, V. N. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5228 · Cited by 281 · see citing works

Functional Estrogen Receptors in the Mitochondria of Breast Cancer Cells

Pedram, A., Razandi, M., Wallace, D. C., & Levin, E. R. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-11-1013 · Cited by 280 · see citing works

Aging and Fertility Patterns in Wild Chimpanzees Provide Insights into the Evolution of Menopause

Thompson, M. E., Jones, J. H., Pusey, A. E., Brewer-Marsden, S., Goodall, J. R., Marsden, D. W., Matsuzawa, T., Nishida, T., Reynolds, V., Sugiyama, Y., et al. (2007) · Current Biology · doi:10.1016/j.cub.2007.11.033 · Cited by 279 · see citing works

Lifespan Extension and Rescue of Spongiform Encephalopathy in Superoxide Dismutase 2 Nullizygous Mice Treated with Superoxide Dismutase–Catalase Mimetics

Melov, S., Doctrow, S. R., Schneider, J. A., Haberson, J., Patel, M., Coskun, P. E., Huffman, K. D., Wallace, D. C., & Malfroy, B. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-21-08348.2001 · Cited by 277 · see citing works

Mitochondrial localization of ERα and ERβ in human MCF7 cells

Chen, J. Q., Delannoy, M., Cooke, C., & Yager, J. D. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00508.2003 · Cited by 272 · see citing works

Nuclear receptor coregulators: modulators of pathology and therapeutic targets

Lonard, D. M., & O’Malley, B. W. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.100 · Cited by 271 · see citing works

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications

Chen, J., Cammarata, P. R., Baines, C. P., & Yager, J. D. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2009.06.001 · Cited by 266 · see citing works

Longevit of British breeds of dog and its relationships with‐sex, size, cardiovascular variables and disease

Michell, A. R. (1999) · Veterinary Record · doi:10.1136/vr.145.22.625 · Cited by 261 · see citing works

17β‐oestradiol up‐regulates longevity‐related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFκB cascade

Borrás, C., Gambini, J., Gómez-Cabrera, M. C., Sastre, J., Pallardó, F., Mann, G., & Viña, J. (2005) · Aging Cell · doi:10.1111/j.1474-9726.2005.00151.x · Cited by 257 · see citing works

Mortality and Survival: Comparison of Eunuchs with Intact Men and Women in a Mentally Retarded Population

Hamilton, J. B., & Mestler, G. E. (1969) · Journal of Gerontology · doi:10.1093/geronj/24.4.395 · Cited by 256 · see citing works

Effects of Transdermal Testosterone on Bone and Muscle in Older Men with Low Bioavailable Testosterone Levels, Low Bone Mass, and Physical Frailty

Kenny, R. A., Kleppinger, A., Annis, K., Rathier, M., Browner, B., Judge, J. O., & McGee, D. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02865.x · Cited by 250 · see citing works

Role of mitochondria in steroidogenesis

Papadopoulos, V., & Miller, W. L. (2012) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2012.05.002 · Cited by 249 · see citing works

Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis

Mattingly, K. A., Ivanova, M. M., Riggs, K. A., Wickramasinghe, N. S., Barch, M. J., & Klinge, C. M. (2008) · Molecular Endocrinology · doi:10.1210/me.2007-0029 · Cited by 243 · see citing works

Estrogen Prevents Cardiomyocyte Apoptosis through Inhibition of Reactive Oxygen Species and Differential Regulation of p38 Kinase Isoforms

Kim, J. K., Pedram, A., Razandi, M., & Levin, E. R. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m511024200 · Cited by 220 · see citing works

Origin and evolution of the free radical theory of aging: a brief personal history, 1954–2009

Harman, D. (2009) · Biogerontology · doi:10.1007/s10522-009-9234-2 · Cited by 219 · see citing works

Modulation of Estrogen Receptor-α Transcriptional Activity by the Coactivator PGC-1

Tcherepanova, I. Y., Puigserver, P., Norris, J. D., Spiegelman, B. M., & McDonnell, D. P. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001364200 · Cited by 218 · see citing works

Estrogen suppresses brain mitochondrial oxidative stress in female and male rats

Razmara, A., DUCKLES, S. P., Krause, D. N., & Procaccio, V. (2007) · Brain Research · doi:10.1016/j.brainres.2007.08.036 · Cited by 214 · see citing works

RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress

Kirby, K., Hu, J., Hilliker, A. J., & Phillips, J. P. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.252342899 · Cited by 208 · see citing works

Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells

Tatone, C., Carbone, M. C., Falone, S., Aimola, P., Giardinelli, A., Caserta, D., Marci, R., Pandolfi, A., Ragnelli, A. M., & Amicarelli, F. (2006) · Molecular Human Reproduction · doi:10.1093/molehr/gal080 · Cited by 197 · see citing works

Effect of estrogens on skin aging and the potential role of SERMs

Thornton, J. (2007) · Clinical Interventions in Aging · doi:10.2147/cia.s798 · Cited by 193 · see citing works

The lifespan of Korean eunuchs

Min, K., Lee, C., & Park, H.-N. (2012) · Current Biology · doi:10.1016/j.cub.2012.06.036 · Cited by 193 · see citing works

Free radical theory of aging: The “free radical” diseases

Harman, D. (1984) · AGE · doi:10.1007/bf02431866 · Cited by 190 · see citing works

About “Origin and evolution of the free radical theory of aging: a brief personal history, 1954–2009”

Harman, D. (2009) · Biogerontology · doi:10.1007/s10522-009-9253-z · Cited by 187 · see citing works

Estrogen receptor specificity for the effects of estrogen in ovariectomized mice

Lindberg, M., Weihua, Z., Andersson, N., Movérare, S., Gao, H., Vidal, O., Erlandsson, M. C., Windahl, S. H., Andersson, G., Lubahn, D., et al. (2002) · Journal of Endocrinology · doi:10.1677/joe.0.1740167 · Cited by 179 · see citing works

Estrogen promotes cutaneous wound healing via estrogen receptor β independent of its antiinflammatory activities

Campbell, L., Emmerson, E., Davies, F., Gilliver, S. C., Krust, A., Chambon, P., Ashcroft, G. S., & Hardman, M. J. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20100500 · Cited by 175 · see citing works

Estrogen-Induced Generation of Reactive Oxygen and Nitrogen Species, Gene Damage, and Estrogen-Dependent Cancers

Roy, D., Cai, Q., Felty, Q. H., & Narayan, S. (2007) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/15287390600974924 · Cited by 161 · see citing works

Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor α in Brain Endothelial Cells

Razmara, A., Sunday, L., Stirone, C., Wang, X. B., Krause, D. N., Duckles, S. P., & Procaccio, V. (2008) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.134072 · Cited by 161 · see citing works

Clinical Meaningfulness of the Changes in Muscle Performance and Physical Function Associated With Testosterone Administration in Older Men With Mobility Limitation

Travison, T. G., Basaria, S., Storer, T. W., Jette, A. M., Miciek, R., Farwell, W. R., Choong, K., Lakshman, K., Mazer, N. A., Coviello, A. D., et al. (2011) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glr100 · Cited by 160 · see citing works

Minireview: Recent Advances in Extranuclear Steroid Receptor Actions

Hammes, S. R., & Levin, E. R. (2011) · Endocrinology · doi:10.1210/en.2011-1470 · Cited by 148 · see citing works

Lifespan and testosterone

Nieschlag, E., Nieschlag, S., & Behre, H. M. (1993) · Nature · doi:10.1038/366215a0 · Cited by 148 · see citing works

Age-Related Changes in the Ultrastructure of the Resting Follicle Pool in Human Ovaries1

de Bruin, J. P., Dorland, M., Spek, E. R., Posthuma, G., van Haaften, M., Looman, C. W. N., & Velde, E. R. T. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.015784 · Cited by 147 · see citing works

The menopause and aging, a comparative perspective

Finch, C. E. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.03.010 · Cited by 145 · see citing works

Mitochondrial hormesis links low‐dose arsenite exposure to lifespan extension

Schmeisser, S., Schmeißer, K., Weimer, S., Groth, M., Priebe, S., Fazius, E., Kuhlow, D., Pick, D., Einax, J. W., Guthke, R., et al. (2013) · Aging Cell · doi:10.1111/acel.12076 · Cited by 142 · see citing works

Binding of MCF‐7 cell mitochondrial proteins and recombinant human estrogen receptors α and β to human mitochondrial dna estrogen response elements

Chen, J. Q., Eshete, M., Alworth, W. L., & Yager, J. D. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20178 · Cited by 142 · see citing works

Age-related increase in mitochondrial superoxide generation in the testosterone-producing cells of Brown Norway rat testes: relationship to reduced steroidogenic function?

Chen, H., Cangello, D. L., Benson, S., Folmer, J. S., Zhu, H., Trush, M. A., & Zirkin, B. R. (2001) · Experimental Gerontology · doi:10.1016/s0531-5565(01)00118-8 · Cited by 139 · see citing works

The reproductive endocrinology of the menopausal transition

Butler, L. E., & Santoro, N. F. (2011) · Steroids · doi:10.1016/j.steroids.2011.02.026 · Cited by 131 · see citing works

Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization

Seifer, D. B., DeJesus, V., & Hubbard, K. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)04214-0 · Cited by 130 · see citing works

Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling

Felty, Q. H., Singh, K. P., & Roy, D. (2005) · Oncogene · doi:10.1038/sj.onc.1208667 · Cited by 121 · see citing works

The role of estrogen deficiency in skin ageing and wound healing

Emmerson, E., & Hardman, M. J. (2012) · Biogerontology · doi:10.1007/s10522-011-9322-y · Cited by 118 · see citing works

The mitochondrial theory of aging: dead or alive?

Jacobs, H. T. (2003) · Aging Cell · doi:10.1046/j.1474-9728.2003.00032.x · Cited by 117 · see citing works

Subcellular distribution of native estrogen receptor α and β isoforms in rabbit uterus and ovary

Monje, P. V., & Boland, R. (2001) · Journal of Cellular Biochemistry · doi:10.1002/jcb.1182 · Cited by 114 · see citing works

A Mutation in the Inner Mitochondrial Membrane Peptidase 2-Like Gene (Immp2l) Affects Mitochondrial Function and Impairs Fertility in Mice1

Lu, B., Poirier, C., Gáspár, T., Gratzke, C., Harrison, W. R., Busija, D. W., Matzuk, M. M., Andersson, K., Overbeek, P. A., & Bishop, C. E. (2007) · Biology of Reproduction · doi:10.1095/biolreprod.107.065987 · Cited by 114 · see citing works

Aging and Declining Testosterone: Past, Present, and Hopes for the Future

Zirkin, B. R., & Tenover, J. L. (2012) · Journal of Andrology · doi:10.2164/jandrol.112.017160 · Cited by 109 · see citing works

Estrogen down-regulates uncoupling proteins and increases oxidative stress in breast cancer

Sastre‐Serra, J., Valle, A., Garau, I., Oliver, J., & Roca, P. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.11.025 · Cited by 104 · see citing works

Aging and hormones of the hypothalamo-pituitary axis: Gonadotropic axis in men and somatotropic axes in men and women

Veldhuis, J. D. (2008) · Ageing Research Reviews · doi:10.1016/j.arr.2007.12.005 · Cited by 98 · see citing works

Estrogen's Effects on Mitochondrial Gene Expression: Mechanisms and Potential Contributions to Estrogen Carcinogenesis

CHEN, J., & Yager, J. D. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1322.030 · Cited by 92 · see citing works

Inactivation of estrogen receptor α in bone‐forming cells induces bone loss in female mice

Määttä, J. A., Büki, K. G., Gu, G., Alanne, M. H., Vääräniemi, J. P., Liljenbäck, H., POUTANEN, M. H., Härkönen, P. L., & Väänänen, K. (2012) · The FASEB Journal · doi:10.1096/fj.12-213587 · Cited by 87 · see citing works

Testosterone improves the regeneration of old and young mouse skeletal muscle

Serra, C., Tangherlini, F., Rudy, S., Lee, D., Toraldo, G., Sandor, N. L., Zhang, A., Jasuja, R., & Bhasin, S. (2013) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gls083 · Cited by 87 · see citing works

Subcellular distribution of native estrogen receptor α and β subtypes in cultured human lens epithelial cells

Cammarata, P. R., Chu, S., Moor, A. N., Wang, Z., Yang, S., & Simpkins, J. W. (2004) · Experimental Eye Research · doi:10.1016/j.exer.2003.09.027 · Cited by 82 · see citing works

Temporal Relationships Among Testosterone Production, Steroidogenic Acute Regulatory Protein (StAR), and P450 Side‐Chain Cleavage Enzyme (P450scc) During Leydig Cell Aging

Luo, L., Chen, H., & Zirkin, B. R. (2005) · Journal of Andrology · doi:10.1002/j.1939-4640.2005.tb02868.x · Cited by 81 · see citing works

Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement

Ibebunjo, C., Eash, J. K., Li, C., Ma, Q., & Glass, D. J. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00402.2010 · Cited by 81 · see citing works

Autophagic deficiency is related to steroidogenic decline in aged rat Leydig cells

Li, W.-R., Chen, L., Chang, Z., Hua, X., Liu, T., Zhang, Y.-Q., Li, G.-Y., Zhou, F., Gong, Y., Gao, Z., et al. (2011) · Asian Journal of Andrology · doi:10.1038/aja.2011.85 · Cited by 81 · see citing works

Menopause and Mitochondria

Henderson, V. W., & Brinton, R. D. (2010) · Progress in brain research · doi:10.1016/s0079-6123(10)82003-5 · Cited by 80 · see citing works

Environmental effects on longevity in the male rat: Exercise, mating, castration and restricted feeding

Drori, D., & Folman, Y. (1976) · Experimental Gerontology · doi:10.1016/0531-5565(76)90007-3 · Cited by 75 · see citing works

Rationale and design of the Kronos Early Estrogen Prevention Study (KEEPS) and the KEEPS cognitive and affective sub study (KEEPS Cog)

Wharton, W., Gleason, C. E., Miller, V. M., & Asthana, S. (2013) · Brain Research · doi:10.1016/j.brainres.2013.04.011 · Cited by 74 · see citing works

Pulsatile iv Infusion of Recombinant Human LH in Leuprolide-Suppressed Men Unmasks Impoverished Leydig-Cell Secretory Responsiveness to Midphysiological LH Drive in the Aging Male

Mulligan, T., Iranmanesh, A., & Veldhuis, J. D. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.11.8004 · Cited by 71 · see citing works

Early, But Not Late Onset Estrogen Replacement Therapy Prevents Oxidative Stress and Metabolic Alterations Caused by Ovariectomy

López-Grueso, R., Gambini, J., Abdelaziz, K. M., Monleón, D., Díaz, A., Alami, M. E., Bonet-Costa, V., Borrás, C., & Viña, J. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.5112 · Cited by 69 · see citing works

Myocyte Androgen Receptors Increase Metabolic Rate and Improve Body Composition by Reducing Fat Mass

Fernando, S. M., Rao, P., Niel, L., Chatterjee, D., Stagljar, M., & Monks, D. A. (2010) · Endocrinology · doi:10.1210/en.2010-0018 · Cited by 69 · see citing works

Aging and Luteinizing Hormone Effects on Reactive Oxygen Species Production and DNA Damage in Rat Leydig Cells1

Beattie, M. C., Chen, H., Fan, J., Papadopoulos, V., Miller, P. S., & Zirkin, B. R. (2013) · Biology of Reproduction · doi:10.1095/biolreprod.112.107052 · Cited by 68 · see citing works

Studies of the Human Testis. XVIII. Simultaneous Measurement of Nine Intratesticular Steroids: Evidence for Reduced Mitochondrial Function in Testis of Elderly Men*

Takahashi, J. A., Higashi, Y., Lanasa, J. A., Yoshida, K., Winters, S. J., Oshima, H., & Troen, P. (1983) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-56-6-1178 · Cited by 64 · see citing works

Expression and localization of estrogen receptor α in the C2C12 murine skeletal muscle cell line

Milanesi, L., de Boland, A. R., & Boland, R. (2008) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21706 · Cited by 64 · see citing works

Electron microscopic visualization of membrane-mediated uptake and translocation of estrogen-BSA:colloidal gold by hep G2 cells

Moats, R. K., & Ramirez, V. (2000) · Journal of Endocrinology · doi:10.1677/joe.0.1660631 · Cited by 60 · see citing works

Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in Male mice

Guo, W., Wong, S., Li, M., Liang, W., Liesa, M., Serra, C., Jasuja, R., Bartke, A., Kirkland, J. L., Shirihai, O., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051180 · Cited by 59 · see citing works

Differential effects of olanzapine on the gene expression of superoxide dismutase and the low affinity nerve growth factor receptor

Li, X., Chlan‐Fourney, J., Juorio, A. V., Bennett, V. L., Shrikhande, S., Keegan, D. L., Jin, Q., & Boulton, A. A. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990401)56:1 · Cited by 57 · see citing works

Estrogen and the regulation of mitochondrial structure and function in the brain

Arnold, S., Victor, M. B., & Beyer, C. (2012) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2012.01.012 · Cited by 57 · see citing works

Actions of 17β-estradiol and testosterone in the mitochondria and their implications in aging

Vasconsuelo, A., Milanesi, L., & Boland, R. (2013) · Ageing Research Reviews · doi:10.1016/j.arr.2013.09.001 · Cited by 55 · see citing works

Early Natural Menopause and the Duration of Postmenopausal Life

Snowdon, D. A. (1990) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1990.tb03537.x · Cited by 52 · see citing works

"Oxidative stress": effects of mild endurance training and testosterone treatment on rat gastrocnemius muscle

Pansarasa, O., D’Antona, G., Gualea, M. R., Marzani, B., Pellegrino, M. A., & Marzatico, F. (2002) · European Journal of Applied Physiology · doi:10.1007/s00421-002-0668-3 · Cited by 48 · see citing works

Pleiotropic actions of estrogen: a mitochondrial matter

Velarde, M. C. (2012) · Physiological Genomics · doi:10.1152/physiolgenomics.00155.2012 · Cited by 47 · see citing works

Rapid Uptake and Binding of Estradiol-17β-6-(O-carboxymethyl)oxime:125I-labeled Bsa by Female Rat Liver1

Moats, R. K., & Ramirez, V. D. (1998) · Biology of Reproduction · doi:10.1095/biolreprod58.2.531 · Cited by 44 · see citing works

Menstrual Cycles Continue into Advanced Old Age in the Common Chimpanzee(Pan troglodytes)1

Agnès Lacreuse, A., Chennareddi, L. S., Gould, K. G., Hawkes, K., Wijayawardana, S. R., Chen, J., Easley, K. A., & Herndon, J. G. (2008) · Biology of Reproduction · doi:10.1095/biolreprod.108.068494 · Cited by 43 · see citing works

Different expression of α and β mitochondrial estrogen receptors in the aging rat brain: Interaction with respiratory complex V

Álvarez‐Delgado, C., Mendoza-Rodríguez, C. A., Picazo, O., & Cerbón, M. A. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.01.015 · Cited by 41 · see citing works

Antioxidant effect of estrogen on bovine aortic endothelial cells

Song, J., Kim, M., Jo, H.-H., Hwang, S.-J., Chae, B., Chung, J., Kwon, D.-J., Lew, Y.-O., Lim, Y.-T., Kim, J.-H., et al. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.07.006 · Cited by 34 · see citing works

False positives in MALDI-TOF detection of ERβ in mitochondria

Schwend, T., & Gustafsson, J.-Α. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.164 · Cited by 34 · see citing works

Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor β and AP‐1 recruitment to adjacent promoter binding sites

Ivanova, M. M., Luken, K. H., Zimmer, A. S., Lenzo, F. L., Smith, R. J., Arteel, M. W., Kollenberg, T. J., Mattingly, K. A., & Klinge, C. M. (2011) · The FASEB Journal · doi:10.1096/fj.10-169029 · Cited by 32 · see citing works

Role of wild-type estrogen receptor-β in mitochondrial cytoprotection of cultured normal male and female human lens epithelial cells

Flynn, J. M., Dimitrijevich, S. D., Younes, M., Skliris, G. P., Murphy, L. C., & Cammarata, P. R. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90407.2008 · Cited by 31 · see citing works

Relaxin and Castration in Male Mice Protect from, but Testosterone Exacerbates, Age-Related Cardiac and Renal Fibrosis, Whereas Estrogens Are an Independent Determinant of Organ Size

Hewitson, T. D., Zhao, C., Wigg, B., Lee, S. W., Simpson, E. R., Boon, W. C., & Samuel, C. S. (2011) · Endocrinology · doi:10.1210/en.2011-1311 · Cited by 29 · see citing works

Andropause or Male Menopause? Rationale for Testosterone Replacement Therapy in Older Men with Low Testosterone Levels

Cunningham, G. R. (2013) · Endocrine Practice · doi:10.4158/ep13217.ra · Cited by 24 · see citing works

17�-Estradiol Protects Mitochondrial Functions through Extracellular-Signal-Regulated Kinase in C2C12 Muscle Cells

Ronda, A. C., Vasconsuelo, A., & Boland, R. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000354502 · Cited by 21 · see citing works

Subcellular effects of myocyte-specific androgen receptor overexpression in mice

Musa, M., Fernando, S. M., Chatterjee, D., & Monks, D. A. (2011) · Journal of Endocrinology · doi:10.1530/joe-11-0071 · Cited by 19 · see citing works

Correspondence regarding Schwend and Gustafsson, “False positives in MALDI-TOF detection of ERβ in mitochondria”

Yang, S., Prókai, L., & Simpkins, J. W. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.05.009 · Cited by 16 · see citing works

90146514 Early natural menopause and the duration of postmenopausal life. Findings from a mathematical model of life expectancy

Snowdon, D. A. (1990) · Maturitas · doi:10.1016/0378-5122(90)90047-a · Cited by 8 · see citing works

Reply to Turner and Kerber

Velarde, M. C. (2013) · Physiological Genomics · doi:10.1152/physiolgenomics.00053.2013 · Cited by 2 · see citing works

Mammalian Mitochondria and Aging: An Update

Kauppila, T. E. S., Kauppila, J. H. K., & Larsson, N.-G. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2016.09.017 · Cited by 578 · see citing works

Brain aging and neurodegeneration: from a mitochondrial point of view

Grimm, A., & Eckert, A. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14037 · Cited by 565 · see citing works

Sex Differences in Traumatic Brain Injury: What We Know and What We Should Know

Gupte, R. P., Brooks, W. M., Vukas, R. R., Pierce, J. D., & Harris, J. L. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2018.6171 · Cited by 533 · see citing works

Mitochondria: A central target for sex differences in pathologies

Ventura-Clapier, R., Moulin, M., Piquereau, J., Lemaire, C., Mericskay, M., Veksler, V., & Garnier, A. (2017) · Clinical Science · doi:10.1042/cs20160485 · Cited by 371 · see citing works

Role of Estrogen and Other Sex Hormones in Brain Aging. Neuroprotection and DNA Repair

Zárate, S., Stevnsner, T., & Gredilla, R. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00430 · Cited by 286 · see citing works

Muscle metabolism and atrophy: let’s talk about sex

Rosa-Caldwell, M. E., & Greene, N. P. (2019) · Biology of Sex Differences · doi:10.1186/s13293-019-0257-3 · Cited by 202 · see citing works

Mitophagy and age-related pathologies: Development of new therapeutics by targeting mitochondrial turnover

Palikaras, K., Daskalaki, I., Markaki, M., & Tavernarakis, N. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.04.005 · Cited by 175 · see citing works

Gastro-Intestinal and Oral Microbiome Signatures Associated with Healthy Aging

Singh, H., Torralba, M. G., Moncera, K. J., DiLello, L., Petrini, J., Nelson, K. E., & Pieper, R. (2019) · GeroScience · doi:10.1007/s11357-019-00098-8 · Cited by 158 · see citing works

Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ros homeostasis in young mouse heart and brain

Khalifa, A. R. M., Abdel‐Rahman, E. A., Mahmoud, A. M., Ali, M. H., Noureldin, M., Saber, S. H., Mohsen, M., & Ali, S. S. (2017) · Physiological Reports · doi:10.14814/phy2.13125 · Cited by 154 · see citing works

Mitochondria, Estrogen and Female Brain Aging

Lejri, I., Grimm, A., & Eckert, A. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00124 · Cited by 141 · see citing works

Estrogens, Estrogen Receptors Effects on Cardiac and Skeletal Muscle Mitochondria

Ventura‐Clapier, R., Piquereau, J., Veksler, V., & Garnier, A. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00557 · Cited by 134 · see citing works

Role of Sex Hormones on Brain Mitochondrial Function, with Special Reference to Aging and Neurodegenerative Diseases

Gaignard, P., Lière, P., Thérond, P., Schumacher, M., Slama, A., & Guennoun, R. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00406 · Cited by 127 · see citing works

On the central role of mitochondria dysfunction and oxidative stress in Alzheimer’s disease

Tobore, T. O. (2019) · Neurological Sciences · doi:10.1007/s10072-019-03863-x · Cited by 110 · see citing works

Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study

HRRT [11C ]PBR28 study group, Tuisku, J., Plavén‐Sigray, P., Gaiser, E., Airas, L. M., Al‐Abdulrasul, H., Brück, A., Carson, R. E., Chen, M.-K., Cosgrove, K., et al. (2019) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-019-04403-7 · Cited by 108 · see citing works

Alzheimer, mitochondria and gender

Grimm, A., Mensah‐Nyagan, A. G., & Eckert, A. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.04.012 · Cited by 107 · see citing works

Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain Diseases

Preciados, M., Yoo, C., & Roy, D. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17122086 · Cited by 105 · see citing works

Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function

Singh, B., Schoeb, T. R., Bajpai, P., Slominski, A. T., & Singh, K. K. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0765-9 · Cited by 107 · see citing works

From Menopause to Neurodegeneration—Molecular Basis and Potential Therapy

Cheng, Y., Lin, C., & Lane, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168654 · Cited by 94 · see citing works

Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma

Srinivasainagendra, V., Sandel, M. J., Singh, B., Sundaresan, A., Mooga, V. P., Bajpai, P., Tiwari, H. K., & Singh, K. K. (2017) · Genome Medicine · doi:10.1186/s13073-017-0420-6 · Cited by 82 · see citing works

The Pleiotropic Effect of Physical Exercise on Mitochondrial Dynamics in Aging Skeletal Muscle

Barbieri, E., Agostini, D., Polidori, E., Potenza, L., Guescini, M., Lucertini, F., Annibalini, G., Stocchi, L., Santi, M. D., & Stocchi, V. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/917085 · Cited by 79 · see citing works

GPER mediates the effects of 17β-estradiol in cardiac mitochondrial biogenesis and function

Sbert-Roig, M., Bauzá-Thorbrügge, M., Galmés-Pascual, B. M., Capllonch-Amer, G., García-Palmer, F., Lladó, I., Proenza, A. M., & Gianotti, M. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.11.027 · Cited by 58 · see citing works

Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease

Ruszkiewicz, J. A., Miranda‐Vizuete, A., Tinkov, A. A., Геннадиевна, С. М., Skalny, A. V., Tsatsakis, A. M., & Aschner, M. (2019) · Journal of Molecular Neuroscience · doi:10.1007/s12031-018-1241-9 · Cited by 47 · see citing works

The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases

Carvalho, C., Correia, S. C., Cardoso, S., Plácido, A. I., Candeias, E., Duarte, A. I., & Moreira, P. I. (2015) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2015.1058160 · Cited by 43 · see citing works

Sarcopenia: pathogenesis and diagnosis

Grigorieva, I. I., Raskina, T. A., Letaeva, M. V., Степановна, М. О., Averkieva, J., Masenko, V. L., & Коков, А. Н. (2019) · Fundamental and Clinical Medicine · doi:10.23946/2500-0764-2019-4-4-105-116 · Cited by 43 · see citing works

Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries

Rutkai, I., Dutta, S., Katakam, P. V., & Busija, D. W. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00231.2015 · Cited by 37 · see citing works

A Review and Assessment of the Shared-Pathway Hypothesis for the Maintenance of Signal Honesty in Red Ketocarotenoid-Based Coloration

Powers, M. J., & Hill, G. E. (2021) · Integrative and Comparative Biology · doi:10.1093/icb/icab056 · Cited by 34 · see citing works

Oxidative testicular injury: effect of l-leucine on redox, cholinergic and purinergic dysfunctions, and dysregulated metabolic pathways

Erukainure, O. L., Atolanı, O., Banerjee, P., Abel, R., Pooe, O. J., Adeyemı, O. S., Preißner, R., Chukwuma, C. I., Koorbanally, N. A., & Islam, M. S. (2021) · Amino Acids · doi:10.1007/s00726-021-02954-4 · Cited by 31 · see citing works

Sex differences in redox homeostasis in renal disease

Mitchell, T., Miguel, C. D., & Gohar, E. Y. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101489 · Cited by 31 · see citing works

On the Etiopathogenesis and Pathophysiology of Alzheimer’s Disease: A Comprehensive Theoretical Review

Tobore, T. O. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-181052 · Cited by 31 · see citing works

TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism

Acharya, T. K., Kumar, A., Majhi, R. K., Kumar, S., Chakraborty, R., Tiwari, A. K., Smalla, K., Liu, X., Chang, Y., Gundelfinger, E. D., et al. (2022) · Mitochondrion · doi:10.1016/j.mito.2022.10.001 · Cited by 30 · see citing works

Quantifying Age-Related Changes in Skin Wound Metabolism Using In Vivo Multiphoton Microscopy

Jones, J. D., Ramser, H. E., Woessner, A. E., Veves, A., & Quinn, K. P. (2019) · Advances in Wound Care · doi:10.1089/wound.2019.1030 · Cited by 27 · see citing works

Caloric restriction-mimetics for the reduction of heart failure risk in aging heart: with consideration of gender-related differences

Pang, L., Jiang, X., Lian, X., Chen, J., Song, E., Jin, L., Xia, Z., Ma, H., & Cai, Y. (2022) · Military Medical Research · doi:10.1186/s40779-022-00389-w · Cited by 26 · see citing works

Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features

Pesaresi, M., Giatti, S., Spezzano, R., Romano, S., Diviccaro, S., Borsello, T., Mitro, N., Caruso, D., García‐Segura, L. M., & Melcangi, R. C. (2018) · Biology of Sex Differences · doi:10.1186/s13293-018-0164-z · Cited by 25 · see citing works

Mitochondria as the target for disease related hormonal dysregulation

Shaw, G. A. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100350 · Cited by 24 · see citing works

Genetic variant in NDUFS1 gene is associated with schizophrenia and negative symptoms in Han Chinese

Zhu, Y., Wang, Z., Ni, J., Zhang, Y., Chen, M., Cai, J., Li, X., Zhang, W., & Zhang, C. (2014) · Journal of Human Genetics · doi:10.1038/jhg.2014.94 · Cited by 24 · see citing works

Distinct designer diamines promote mitophagy, and thereby enhance healthspan in C. elegans and protect human cells against oxidative damage

Srivastava, V., Zelmanovich, V., Shukla, V., Abergel, R., Cohen, I., Ben‐Sasson, S. A., & Gross, E. (2022) · Autophagy · doi:10.1080/15548627.2022.2078069 · Cited by 24 · see citing works

Catalase, a therapeutic target in the reversal of estrogen-mediated aging

Elliot, S. J., Catanuto, P., Pereira‐Simon, S., Xia, X., Pastar, I., Thaller, S. R., Head, C. R., Stojadinović, O., Tomic‐Canic, M., & Glassberg, M. K. (2021) · Molecular Therapy · doi:10.1016/j.ymthe.2021.06.020 · Cited by 22 · see citing works

Mitochondrion: Features, functions and comparative analysis of specific probes in detecting sperm cell damages

Srivastava, N., & Pande, M. (2016) · Asian Pacific Journal of Reproduction · doi:10.1016/j.apjr.2016.10.008 · Cited by 22 · see citing works

Mitochondrial superclusters influence age of onset of Parkinson’s disease in a gender specific manner in the Cypriot population: A case-control study

Georgiou, A. N., Demetriou, C. A., Heraclides, A., Christou, Y. P., Leonidou, E., Loukaides, P., Yiasoumi, E., Panagiotou, D., Manoli, P., Thomson, P. A., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0183444 · Cited by 22 · see citing works

Nonylphenol and Octylphenol Differently Affect Cell Redox Balance by Modulating the Nitric Oxide Signaling

Magnifico, M. C., Xhani, M., Popov, M., Saso, L., Sarti, P., & Arese, M. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/1684827 · Cited by 22 · see citing works

Oral microbiome diversity and diet quality in relation to mortality.

Shen, J., Chen, H., Zhou, X., Huang, Q.-M., Garay, L., Zhao, M., Qian, S.-J., Zong, G., Yan, Y., Wang, X., et al. (2024) · Journal of Clinical Periodontology · doi:10.1111/jcpe.14050 · Cited by 18 · see citing works

Chlorinated biphenyls effect on estrogen-related receptor expression, steroid secretion, mitochondria ultrastructure but not on mitochondrial membrane potential in Leydig cells

Milon, A., Opydo‐Chanek, M., Tworzydlo, W., Galas, J. F., Pardyak, L., Kamińska, A., Ptak, A., & Kotula‐Balak, M. (2017) · Cell and Tissue Research · doi:10.1007/s00441-017-2596-x · Cited by 21 · see citing works

Gender difference in relationship between serum ferritin and 25-hydroxyvitamin D in Korean adults

Seong, J.-M., Yoon, Y. S., Lee, K. S., Bae, N. Y., Gi, M. Y., & Yoon, H. J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177722 · Cited by 24 · see citing works

Mitochondria and Sex-Specific Cardiac Function

Vona, R., Ascione, B., Malorni, W., & Straface, E. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-77932-4_16 · Cited by 21 · see citing works

Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus

Zárate, S., Astiz, M., Magnani, N., Imsen, M., Merino, F., Álvarez, S., Reinés, A. G., & Seilicovich, A. (2017) · Journal of Endocrinology · doi:10.1530/joe-16-0451 · Cited by 19 · see citing works

The antidepressant and anxiolytic effect of GPER on translocator protein (TSPO) via protein kinase a (PKA) signaling in menopausal female rats

Wang, J., Li, H., Shen, S.-Y., Zhang, J., Liang, L., Huang, H., Li, B., Wu, G.-C., Zhang, Y., & Yu, J. M. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2020.105807 · Cited by 19 · see citing works

Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice

Moschinger, M., Hilse, K. E., Rupprecht, A., Zeitz, U., Erben, R. G., Rülicke, T., & Pohl, E. E. (2019) · Biology of Sex Differences · doi:10.1186/s13293-019-0267-1 · Cited by 18 · see citing works

Anabolic-androgenic steroids impair mitochondrial function and redox status in the heart and liver of mice

Carteri, R. B., Kopczynski, A., Rodolphi, M. S., Strogulski, N. R., Wannmacher, C. M. D., de Franceschi, I. D., Hammerschmitt, M. E., Driemeier, D., & Portela, L. V. (2021) · Steroids · doi:10.1016/j.steroids.2021.108861 · Cited by 18 · see citing works

The role of mitochondria in longevity and healthspan

Brand, M. D. (2014) · Longevity & Healthspan · doi:10.1186/2046-2395-3-7 · Cited by 17 · see citing works

The effects of alcohol on testosterone synthesis in men: a review

Smith, S. J., Lopresti, A. L., & Fairchild, T. J. (2023) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2023.2184797 · Cited by 16 · see citing works

PPARGC1A rs8192678 and NRF1 rs6949152 Polymorphisms Are Associated with Muscle Fiber Composition in Women

Yvert, T. P., Miyamoto‐Mikami, E., Tobina, T., Shiose, K., Kakigi, R., Tsuzuki, T., Takaragawa, M., Ichinoseki‐Sekine, N., Pérez, M., Kobayashi, H., et al. (2020) · Genes · doi:10.3390/genes11091012 · Cited by 16 · see citing works

Cardio-Metabolic Health and HRT in Menopause: Novel Insights in Mitochondrial Biogenesis and RAAS

Renke, G., Kemen, E., Scalabrin, P., Braz, C., Baesso, T., & Pereira, M. B. (2023) · Current Cardiology Reviews · doi:10.2174/1573403x19666230206130205 · Cited by 15 · see citing works

Transcriptomic and metabolomic changes might predict frailty in SAMP8 mice

Dacomo, L., Vitola, P. L., Brunelli, L., Messa, L., Micotti, E., Artioli, L., Sinopoli, E., Cecutti, G., Leva, S., Gagliardi, S., et al. (2024) · Aging Cell · doi:10.1111/acel.14263 · Cited by 15 · see citing works

Optimization of cell permeabilization in electron flow based mitochondrial function assays

Lei, X.-H., & Bochner, B. R. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.10.014 · Cited by 15 · see citing works

S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity

Zaręba-Kozioł, M., Bartkowiak, A., Roszkowska, M., Bijata, K., Figiel, I., Halder, A. K., Kamińska, P., Müller, F. E., Basu, S., Zhang, W., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126253 · Cited by 14 · see citing works

Hallmarks of Cancer Cachexia: Sexual Dimorphism in Related Pathways

Satari, S., Mota, I. N. R., Silva, A. C. L., Brito, H. O., Oliveira, P. A., da Costa, R. M. G., & Medeiros, R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26093952 · Cited by 13 · see citing works

Crosstalk between mitochondrial homeostasis and AMPK pathway mediate the receptor-mediated cardioprotective effects of estradiol in ovariectomized female rats

Gowayed, M. A., Zakaraya, Z. Z., Abu‐Samra, N., Elhamammy, R. H., Moneim, L. M. A., Hafez, H. A., Moneam, I. A., Oriquat, G. A., & Kamel, M. A. E.-N. (2024) · PLoS ONE · doi:10.1371/journal.pone.0312397 · Cited by 13 · see citing works

Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats

Moreira, A. C., Silva, A. M., Branco, A. F., Baldeiras, I., Pereira, G. C., Seiça, R. M. F., Santos, M. S., & Sardão, V. A. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.05.002 · Cited by 12 · see citing works

Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone

Nakamura, N., Vijay, V., Desai, V. G., Hansen, D. K., Han, T., Chang, C., Chen, Y., Harrouk, W. A., Mcintyre, B., Foster, P. M. D., et al. (2018) · Reproductive Toxicology · doi:10.1016/j.reprotox.2018.10.001 · Cited by 11 · see citing works

Emerging Promise of Therapeutic Approaches Targeting Mitochondria in Neurodegenerative Disorders

Rahman, M. M., Tumpa, M. A. A., Rahaman, M. S., Islam, F., Sutradhar, P. R., Ahmed, M., Alghamdi, B. S. A., Hafeez, A., Alexiou, A. T., Perveen, A., et al. (2023) · Current Neuropharmacology · doi:10.2174/1570159x21666230316150559 · Cited by 11 · see citing works

Effect of Moxibustion on Testosterone Secretion and Apoptosis of Spermatogenic Cells in Aging Rats

Yao, C., Zhao, C., Zhang, S., & Liu, S. (2019) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2019/5186408 · Cited by 10 · see citing works

Menstrual Cycle Phase-Based Strength and Conditioning Training for Elite Team Sport Female Athletes

Moore, S. R., Bruinvels, G., & Smith‐Ryan, A. E. (2024) · Strength and conditioning journal · doi:10.1519/ssc.0000000000000879 · Cited by 9 · see citing works

Multifaceted dynamics of circadian timing system influence aging and longevity

Jagota, A., Khan, Z. A., Sharma, S. A., & Priyanka (2025) · Biogerontology · doi:10.1007/s10522-025-10324-w · Cited by 9 · see citing works

Biological age prediction using a DNN model based on pathways of steroidogenesis

Wang, Q., Wang, Z., Mizuguchi, K., & Takao, T. (2025) · Science Advances · doi:10.1126/sciadv.adt2624 · Cited by 7 · see citing works

Estrogen and Mitochondrial Function in Disease

Mooga, V. P., White, C. R., & Giordano‐Mooga, S. (2018) · InTech eBooks · doi:10.5772/intechopen.73015 · Cited by 8 · see citing works

Postmenopausal sarcopenia and Alzheimer's disease: The interplay of mitochondria, insulin resistance, and myokines

Farhana, F., Sultana, M. A., Hia, R. A., & Hegde, V. K. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106501 · Cited by 7 · see citing works

Sarcopenia and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Narrative Review

Abenavoli, L., Statsenko, M., Scarlata, G. G. M., Morano, D., Myazin, R. G., & Emelyanov, D. (2024) · Livers · doi:10.3390/livers4040035 · Cited by 7 · see citing works

Acute LPS exposure increases synaptosomal metabolism during estrus but not diestrus

Shaw, G. A., Hyer, M. M., Dustin, E., Dyer, S. K., Targett, I. L., & Neigh, G. N. (2021) · Physiology & Behavior · doi:10.1016/j.physbeh.2021.113523 · Cited by 7 · see citing works

Low mitochondrial DNA copy number of resected cecum appendix correlates with high severity of acute appendicitis

Lee, W.-C., Lin, C., Ko, F.-C., Cheng, W., Lee, M.-H., & Wei, Y. (2018) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2018.07.017 · Cited by 7 · see citing works

The aging male: impact of aging on male reproduction

Akhigbe, R. E., Oyedokun, P. A., Adeogun, A. E., Ogunleye, O. O., Adegbola, C. A., & Akhigbe, T. M. (2025) · Biogerontology · doi:10.1007/s10522-025-10343-7 · Cited by 6 · see citing works

Association between Estradiol/Estrogen Receptors and Cognition: A Knowledge Domain Visualization Analysis of Trends

Wu, M., & Lou, S. (2023) · Medical Science Monitor · doi:10.12659/msm.939676 · Cited by 6 · see citing works

Breastfeeding predicts blood mitochondrial DNA content in adolescents

Cosemans, C., Nawrot, T. S., Janssen, B. G., Vriens, A., Smeets, K., Baeyens, W., Bruckers, L. M., Hond, E. D., Loots, I., Nelen, V., et al. (2020) · Scientific Reports · doi:10.1038/s41598-019-57276-z · Cited by 6 · see citing works

Isosteviol attenuates myocardial ischemia-reperfusion damage by modulating Akt/GSK3β phosphorylation and mitochondrial permeability transition pore opening in female rats

Cordero, V. E. M., Hermann, R., Pazos, M. D. L. M. F., Reznik, F. J., Sánchez, L., Mourglia, J., Perego, J., Vélez, D. E., Prieto, J. M., & Prendes, M. G. M. (2025) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2025.110059 · Cited by 3 · see citing works

Micronutrient Deficiencies and Mitochondrial Dysfunction

Marrs, C. (2015) · CRC Press eBooks · doi:10.1201/b19089-8 · Cited by 3 · see citing works

CYB5R3 overexpression exhibits sexual dimorphism: Mitochondrial and metabolic adaptations in transgenic female mice during calorie restriction

Sánchez‐Mendoza, L. M., Pérez-Sánchez, C., García‐Caballero, C., Pérez-Rodríguez, M., Calero-Rodríguez, P., Vellón-García, B., Moreno, J. A., Burón, M. I., de Cabo, R., González-Reyes, J. A., et al. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.07.034 · Cited by 3 · see citing works

The Pleiotropic Effect of Physical Exercise on Mitochondrial Dynamics in Aging Skeletal Muscle

Barbieri, E., Agostini, D., Polidori, E., Potenza, L., Guescini, M., Lucertini, F., Annibalini, G., Stocchi, L., Santi, M. D., & Stocchi, V. (2016) · Apple Academic Press eBooks · doi:10.1201/b19985-11 · Cited by 3 · see citing works

Sexual Dimorphism in Red Blood Cell Mitochondrial Respiration during Breeding Fasts in King Penguins

Cossin‐Sevrin, N., Bocquet, C., Lemonnier, C., Faulmann, T., Garcin, N., Lejeune, M., Bize, P., Robin, J., Anttila, K., Ruuskanen, S., et al. (2025) · Ecological and Evolutionary Physiology · doi:10.1086/736013 · Cited by 2 · see citing works

Male Spata19 knockout mice have behavioral disorders

Zargar, M., Famitafreshi, H., Ara, M. S., Karimian, M., & Modarressi, M. H. (2020) · Neurology Psychiatry and Brain Research · doi:10.1016/j.npbr.2020.08.007 · Cited by 2 · see citing works

Sex differences in SARS-CoV-2 infections, anti-viral immunity and vaccine responses

Mohanty, A., Sawhney, A., Gupta, S., Rao, V. U. S., Govindaraj, P., Mohanty, S. K., & Jain, V. S. (2022) · Asian Pacific Journal of Tropical Medicine · doi:10.4103/1995-7645.340567 · Cited by 2 · see citing works

How to Prevent Cardiovascular Disorders: Influence of Gonadal Steroids on the Heart

Vujović, S., Tančić‐Gajić, M., Marina, L., Arizanović, Z., Stojanovic, Z., Barac, B., Djogo, A., & Ivović, M. (2018) · ISGE series · doi:10.1007/978-3-319-63540-8_16 · Cited by 2 · see citing works

Sarcopenia is associated with severe coronary atherosclerosis in male patients with coronary artery disease

Raskina, T. A., Grigorieva, I. I., Letaeva, M. V., Ivanov, V. I., & Masenko, V. L. (2020) · Fundamental and Clinical Medicine · doi:10.23946/2500-0764-2020-5-4-46-56 · Cited by 1 · see citing works

The relative copy number of mitochondrial DNA in peripheral blood as a prognostic marker for the development of polycystic ovarian syndrome in west Iraqi women

Hameed, Z. N., Rashied, R. M., & Kareem, S. M. (2025) · Human Gene · doi:10.1016/j.humgen.2025.201442 · Cited by 1 · see citing works

Rice bran supplementation exerts a protective effect against mitochondrial dysfunction associated with high-fat diet consumption in ovariectomized mice

Choi, J., Lee, S.-H., Yang, D., Kim, M., Um, M. Y., & Shin, S. (2025) · Applied Biological Chemistry · doi:10.1186/s13765-025-01016-7 · Cited by 1 · see citing works

The Estrogen–Mitochondria Axis in Bipolar Disorder: From Fluctuating Hormones to Failing Bioenergetics

Zachos, K. A., Behravan, K., Demyati, J., & Andreazza, A. C. (2026) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2026.100723 · Cited by 1 · see citing works

Sex and Sex Hormones in Tissue Homeostasis

Lechner, J., & Gstraunthaler, G. J. A. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.76177 · Cited by 1 · see citing works

Cardiac Mitochondria and Ischemia/Reperfusion Injury—Sex Differences

Drahota, Z., Hlaváčková, M., & Ostadal, B. (2020) · Springer eBooks · doi:10.1007/978-3-030-58677-5_15 · Cited by 1 · see citing works

Sarcopenia and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Narrative ReviewPreprint

Abenavoli, L., Statsenko, M., Scarlata, G. G. M., Morano, D., Myazin, R. G., & Emelyanov, D. (2024) · Preprints.org · doi:10.20944/preprints202408.0591.v1 · Cited by 1 · see citing works

Dynamics of Enhanced Mitochondrial Respiration in Female Compared with Male

Rutkai, I., Dutta, S., Katakam, P. V. G., & Busija, D. W. (2015)

Carnitine metabolism in relation to physical performance and cognition in aging

van der Hoek, M. D. (2020) · doi:10.18174/513041

The Interplay of Progestins, Matrix Metalloproteinases, and the Aging Brain

Porter, K. N. (2020) · doi:10.33915/etd.7973

Sex Hormones as Risk Factors for Dementia

Mante, P. K., & Adomako, N. O. (2022) · Springer eBooks · doi:10.1007/978-981-16-7606-2_4

Steroid hormone receptors in aging and neurodegenerative diseases

Kumar, R., & McEwan, I. J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91141-2.00001-5

APOE4 induces sex-dependent synaptic mitochondrial cholesterol, proteome, and respiratory function alterations in mice

Roland, N. J., Zigmond, J. W., Manganaro, J. E., Estrella, L. D., & Stauch, K. L. (2026) · Neurochemistry International · doi:10.1016/j.neuint.2026.106125 · Cited by 1 · see citing works

Photoperiod, but not testosterone, increases basal metabolic rate in house sparrows

Galante, H., Lane, S. J., Elderbrock, E. K., Kittilson, J. D., Greenlee, K. J., & Greives, T. J. (2026) · Integrative Organismal Biology · doi:10.1093/iob/obag013

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Crino, O. L., Friesen, C. R., Hill, G. E., Leibold, D. C., Recio, P., Salin, K., Wild, K. H., & Noble, D. W. A. (2026) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1002/brv.70199

Actions of 17β-estradiol and testosterone in the mitochondria and their implications in aging

Vasconsuelo, A., Milanesi, L., & Boland, R. (2013) · Ageing Research Reviews · doi:10.1016/j.arr.2013.09.001 · Cited by 55 · see citing works

Role of Sex Hormones on Brain Mitochondrial Function, with Special Reference to Aging and Neurodegenerative Diseases

Gaignard, P., Lière, P., Thérond, P., Schumacher, M., Slama, A., & Guennoun, R. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00406 · Cited by 127 · see citing works

The contribution of mitochondria to age-related skeletal muscle wasting: A sex-specific perspective

Nuccio, A., Nogueira‐Ferreira, R., Moreira‐Pais, A., Attanzio, A., Duarte, J. A., Luparello, C., & Ferreira, R. M. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122324 · Cited by 17 · see citing works

Mitochondria as the target for disease related hormonal dysregulation

Shaw, G. A. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100350 · Cited by 24 · see citing works

Aging and male reproductive function A mitochondrial perspective

Amaral, S. (2012) · Frontiers in Bioscience-Scholar · doi:10.2741/s365 · Cited by 47 · see citing works