Effect of virtual care in type 2 diabetes management – a systematic umbrella review of systematic reviews and meta-analysis
Open accessAbstract
Background: Diabetes is an increasingly prevalent and costly chronic disease worldwide, and a large cause of unnecessary disease burden. To address the growing burden of diabetes, care models should support management of diabetes in primary care to reduce reliance on overstretched hospital-based specialists services. Virtual care presents an opportunity to provide diabetes care remotely, potentially enhancing the accessibility and efficiency of healthcare services. This review aimed to identify existing evidence on the effectiveness of virtual care on diabetes management, and the extent to which video components are included in the evidence base. Methods: The protocol was registered in PROSPERO (CRD42022366125). Systematic search of the databases PubMed, Embase, Medline, Scopus, CINAHL and Cochrane CENTRAL, were conducted for studies on telemedicine, telehealth, or virtual interventions for type 2 diabetes management published between January 2011 to March 2022. The primary outcome was HbA1c, and secondary outcomes were blood glucose control, Body Mass Index (BMI), taking the prescribed medications, and self-management behaviour. The results were reported following the Preferred Reporting Items for Systematic Reviews (PRISMA) checklist. Quality of each review was appraised using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Systematic Reviews and Research Syntheses. Results: From 10,708 articles, 63 underwent full-text review. Thirty systematic reviews were included. Overall quality of the included reviews was high. Among the 30 systematic reviews, there was significant overlap of the primary studies, with 48% of them appearing in multiple reviews. Of the 30 reviews, 28 reported that virtual care improved HbA1c compared to usual care. Meta-analysis of 16 reviews revealed a mean difference of -0.37% (-0.41% to -0.32%), I 2 of 77.1%. Significant non-clinical impacts were noted for BMI and secondary outcomes. Most reviews (25/30) included some studies with video components, however these studies did not disaggregate the impact of video from other aspects of complex interventions such as web-based and telephone support. Conclusions: This umbrella review strengthens the evidence that virtual care significantly improves clinical outcomes in people with type 2 diabetes, primarily affecting HbA1c. Fewer studies addressed other health outcomes such as BMI and taking medications. Effectiveness of virtual care varies by demographic and clinical characteristics, emphasising the need to tailor virtual care interventions to maximise impact. Future research could directly compare and identify the most effective virtual care strategies for different populations, including those with lower digital literacy.
AI snapshot
Written from the paper’s full text.
TL;DR
This umbrella review of 30 systematic reviews found that virtual care significantly improves HbA1c in type 2 diabetes, with a pooled mean difference of −0.37% versus usual care. Most reviews included some video component, but few isolated the effect of video from other virtual care elements.
Key findings
- Of 30 systematic reviews, 28 reported that virtual care improved HbA1c compared with usual care; meta-analysis of 16 reviews found a mean difference of −0.37% (95% CI −0.41% to −0.32%), with I² = 77.1%.
- In a sensitivity analysis restricted to 12 reviews with type 2 diabetes-specific HbA1c measures, the mean reduction was −0.41% (95% CI −0.49% to −0.34%; I² = 80.8%).
- BMI showed no statistically significant difference between virtual care and usual care in meta-analysis of 4 reviews: reduction of 0.13 (95% CI −0.28 to 0.03; I² = 25.5%).
- Most reviews (25/30) included studies with video components, but these studies did not disaggregate the impact of video from other aspects of complex interventions such as web-based and telephone support.
Methods
- Systematic umbrella review of systematic reviews and meta-analyses, registered in PROSPERO (CRD42022366125), reported per PRISMA; searches covered PubMed, Embase, Medline, Scopus, CINAHL, and Cochrane CENTRAL for studies published January 2011 to March 2022.
- Included 30 systematic reviews of virtual care interventions for adults with type 2 diabetes; primary outcome was HbA1c, with secondary outcomes including blood glucose control, BMI, medication adherence, and self-management behaviour.
- Quality was appraised with the Joanna Briggs Institute Critical Appraisal Checklist; meta-analytic estimates used a random-effects inverse-variance model in Stata 15, with heterogeneity assessed by I².
Limitations
- The authors state that relevant studies may have been missed because MeSH terms were not used, given the difficulty of capturing complex video-component interventions with established search terms.
- The authors report significant overlap among primary studies in the included meta-analyses: 404 of 847 studies were at least duplicates (47.7%), which may affect meta-analysis estimates; they did not recalculate estimates excluding duplicates because it was not feasible.
- The authors note possible reporting bias within included reviews and that some included studies did not provide disaggregated outcomes for type 2 diabetes, potentially obscuring true effects for that population.
- Evident from the text: heterogeneity was high (I² = 77.1% overall; 80.8% in the type 2 diabetes sensitivity analysis), and most video-component studies did not isolate the effect of video.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
44 of 78 cited sources checked · 19 supported · 4 flagged · accuracy not yet measured
- Findingcitation
Two reviews reported a reduction in fasting blood glucose with virtual care.
“out of which 2 reviews reported reduction in fasting blood glucose [32, 46]”
Quote in the paperNot a substantial claim2 of 2 sources checked- cites [32] Eberle C, Stichling S. Effect of Telemetric Interventions on Glycated Hemoglobin A1c and Management of Type 2 Diabetes Mellitus: Systematic Meta-Review. J Med Internet Res. 2021;23(2):e23252. https://doi.org/10.2196/23252. source
- cites [46] McDaniel CC, Kavookjian J, Whitley HP. Telehealth delivery of motivational interviewing for diabetes management: A systematic review of randomized controlled trials. Patient Educ Couns. 2021;105(4):805–20. https://doi.org/10.1016/j.pec.2021.07.036. source
The Results > Outcomes section states that fasting blood glucose was not affected by MI-based telehealth. The review reports reductions in A1C, but not in fasting blood glucose. (LLM, conf=0.91)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured
- Findingown data
All seven reviews reported a reduction in blood pressure with virtual care.
“all 7 reviews [22, 27, 32, 35, 37, 44, 46] reported reduction in blood pressure.”
Quote in the paperSubstantial claim6 of 7 sources checked- cites [22] Kaveh MH, Faradonbeh MR, Kaveh S. Telehealth impact on biomedical, psychosocial, and behavioural outcomes in patients with diabetes older than 50 years: A systematic synthesis without meta-analysis. J Telemed Telecare. 2024;30(2):285–304. https://doi.org/10.1177/1357633X211052222. source
- cites [27] Hossain MM, Tasnim S, Sharma R, Sultana A, Shaik AF, Faizah F, et al. Digital interventions for people living with non-communicable diseases in India: A systematic review of intervention studies and recommendations for future research and development. Digit Health. 2019;5:2055207619896153. https://doi.org/10.1177/2055207619896153. source
- cites [32] Eberle C, Stichling S. Effect of Telemetric Interventions on Glycated Hemoglobin A1c and Management of Type 2 Diabetes Mellitus: Systematic Meta-Review. J Med Internet Res. 2021;23(2):e23252. https://doi.org/10.2196/23252. source
- cites [35] Wu C, Wu Z, Yang L, Zhu W, Zhang M, Zhu Q, et al. Evaluation of the clinical outcomes of telehealth for managing diabetes: A PRISMA-compliant meta-analysis. Medicine (Baltimore). 2018;97(43):e12962. https://doi.org/10.1097/MD.0000000000012962. source
- cites [37] Marcolino MS, Maia JX, Alkmim MB, Boersma E, Ribeiro AL. Telemedicine application in the care of diabetes patients: systematic review and meta-analysis. PLoS ONE. 2013;8(11):e79246. https://doi.org/10.1371/journal.pone.0079246. source
In Results of the Review, under 'Association of intervention on the primary and secondary outcomes,' the paper reports no significant effect on either systolic or diastolic blood pressure compared with usual care. Although the point estimates were negative, the paper describes its finding as no blood-pressure effect, contrary to the unqualified claim that this review reported a reduction. (LLM, conf=0.88)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured - cites [44] De Groot J, Wu D, Flynn D, Robertson D, Grant G, Sun J. Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes: A meta-analysis. World J Diabetes. 2021;12(2):170–97. https://doi.org/10.4239/wjd.v12.i2.170. source
- cites [46] McDaniel CC, Kavookjian J, Whitley HP. Telehealth delivery of motivational interviewing for diabetes management: A systematic review of randomized controlled trials. Patient Educ Couns. 2021;105(4):805–20. https://doi.org/10.1016/j.pec.2021.07.036. source
- Findingcitation
Three reviews reported that text-messaging or SMS feedback was equally effective in improving HbA1c compared to a teleconference or telephone appointment with healthcare professionals.
“3 reviews [28, 31, 43] reported that interventions as simple as text-messaging or SMS feedback were equally effective in improving HbA1c, compared to a teleconference or telephone appointment with healthcare professionals.”
Quote in the paperNot a substantial claim2 of 3 sources checked- cites [28] Su D, McBride C, Zhou J, Kelley MS. Does nutritional counseling in telemedicine improve treatment outcomes for diabetes? A systematic review and meta-analysis of results from 92 studies. J Telemed Telecare. 2016;22(6):333–47. https://doi.org/10.1177/1357633X15608297. source
- cites [31] Faruque LI, Wiebe N, Ehteshami-Afshar A, Liu Y, Dianati-Maleki N, Hemmelgarn BR, et al. Effect of telemedicine on glycated hemoglobin in diabetes: a systematic review and meta-analysis of randomized trials. CMAJ. 2017;189(9):E341–64. https://doi.org/10.1503/cmaj.150885. source
The Meta-regression analysis reports that provider-to-patient SMS text messaging was associated with a significantly greater HbA1c benefit than telephone-based systems, not an equal benefit. The paper does not establish a separate comparison with teleconference appointments. (LLM, conf=0.89)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured - cites [43] Correia JC, Meraj H, Teoh SH, Waqas A, Ahmad M, Lapao LV, et al. Telemedicine to deliver diabetes care in low- and middle-income countries: a systematic review and meta-analysis. Bull World Health Organ. 2021;99(3):209–19. https://doi.org/10.2471/BLT.19.250068. source
In Results > Meta-analysis (Table 2; page not provided), SMS, telephone and video-conference interventions have HbA1c estimates with no statistically significant between-group difference (P = 0.66). That supports a comparison, but it does not establish equal effectiveness; the SMS estimate’s 95% confidence interval includes no improvement. This source is one review, not evidence that three reviews reached that conclusion. (LLM, conf=0.87)
Experimental — accuracy not yet measured
- Findingcitation
Three reviews reported that video conferencing was effective in improving HbA1c levels over periods ranging from 3 to 12 months.
“Three reviews [32, 34, 44] reported that video conferencing was effective in improving HbA1c levels over periods ranging from 3–12 months.”
Quote in the paperNot a substantial claim3 of 3 sources checked- cites [32] Eberle C, Stichling S. Effect of Telemetric Interventions on Glycated Hemoglobin A1c and Management of Type 2 Diabetes Mellitus: Systematic Meta-Review. J Med Internet Res. 2021;23(2):e23252. https://doi.org/10.2196/23252. source
- cites [34] McLendon SF. Interactive Video Telehealth Models to Improve Access to Diabetes Specialty Care and Education in the Rural Setting: A Systematic Review. Diabetes Spectr. 2017;30(2):124–36. https://doi.org/10.2337/ds16-0004. source
- cites [44] De Groot J, Wu D, Flynn D, Robertson D, Grant G, Sun J. Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes: A meta-analysis. World J Diabetes. 2021;12(2):170–97. https://doi.org/10.4239/wjd.v12.i2.170. source
The Results (page unavailable) report a significant HbA1c reduction for videoconference interventions. The paper analyzes intervention duration separately, however, and does not establish that the videoconference finding applies specifically across 3–12 months; its Data extraction table includes a five-year intervention with videoconferencing. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Findingcitation
All three reviews of teleconsultation interventions versus usual care reported significant effects on lowering HbA1c levels.
“Of the 3 reviews that analysed the effect of teleconsultation interventions vs usual care, all reported significant effects on lowering HbA1c levels [20, 21, 29].”
Quote in the paperNot a substantial claim1 of 3 sources checked- cites [20] Lee SWH, Chan CKY, Chua SS, Chaiyakunapruk N. Comparative effectiveness of telemedicine strategies on type 2 diabetes management: A systematic review and network meta-analysis. Sci Rep. 2017;7(1):12680. https://doi.org/10.1038/s41598-017-12987-z. source
- cites [21] Tchero H, Kangambega P, Briatte C, Brunet-Houdard S, Retali GR, Rusch E. Clinical Effectiveness of Telemedicine in Diabetes Mellitus: A Meta-Analysis of 42 Randomized Controlled Trials. Telemed J E Health. 2019;25(7):569–83. https://doi.org/10.1089/tmj.2018.0128. source
- cites [29] Su D, Zhou J, Kelley MS, Michaud TL, Siahpush M, Kim J, et al. Does telemedicine improve treatment outcomes for diabetes? A meta-analysis of results from 55 randomized controlled trials. Diabetes Res Clin Pract. 2016;116:136–48. https://doi.org/10.1016/j.diabres.2016.04.019. source
- Interpretationcitation
Findings from this umbrella review align with recent evidence that virtual care interventions, whether short term or long term, are clearly effective in improving the management of type 2 diabetes.
“Findings from this umbrella review align with recent evidence that virtual care interventions, whether short term or long term, are clearly effective in improving the management of type 2 diabetes [48].”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [48] Robson N, Hosseinzadeh H. Impact of Telehealth Care among Adults Living with Type 2 Diabetes in Primary Care: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Int J Environ Res Public Health. 2021;18(22):12171. https://doi.org/10.3390/ijerph182212171. source
The Results (section 3.8; page unavailable) report a significant overall improvement in HbA1c with telehealth, supporting the claim that virtual care can help manage type 2 diabetes. But the paper does not establish effectiveness separately for short- and long-term interventions: section 3.1 lists their durations without comparing outcomes by duration, and the Conclusions call for longitudinal studies to understand long-term effects. Calling interventions 'clearly effective' also overlooks the nonsignificant technology-specific subgroup results. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Findingcitation
Three reviews reported that telemonitoring combined with tele-education and telemonitoring combined with healthcare professional feedback had greater effects.
“Of those, 3 reviews reported telemonitoring combined with tele-education [44] and telemonitoring combined with healthcare professional feedback [45, 48] had greater effects.”
Quote in the paperNot a substantial claim3 of 3 sources checked- cites [44] De Groot J, Wu D, Flynn D, Robertson D, Grant G, Sun J. Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes: A meta-analysis. World J Diabetes. 2021;12(2):170–97. https://doi.org/10.4239/wjd.v12.i2.170. source
The Results (page not available) report that telemonitoring reduced HbA1c and that interventions led by healthcare professionals differed in effect. The Data extraction table also includes telemonitoring studies with professional feedback. But the paper does not report that adding professional feedback to telemonitoring produced greater effects than telemonitoring without it; its subgroup analysis instead reports a greater HbA1c reduction for telemonitoring alone than for telemonitoring combined with tele-education. (LLM, conf=0.82)
Experimental — accuracy not yet measured - cites [45] Hangaard S, Laursen SH, Andersen JD, Kronborg T, Vestergaard P, Hejlesen O, et al. The Effectiveness of Telemedicine Solutions for the Management of Type 2 Diabetes: A Systematic Review, Meta-Analysis, and Meta-Regression. J Diabetes Sci Technol. 2021;17(3):794–825. https://doi.org/10.1177/19322968211064633. source
The Results report greater effects for telemedicine interventions with a monitoring component, and the Discussion reports that another review found improved glycemic control with telemonitoring plus feedback. This paper does not establish that combining telemonitoring specifically with healthcare-professional feedback produced greater effects than telemonitoring without it. The tele-education part is attached to a different citation. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites [48] Robson N, Hosseinzadeh H. Impact of Telehealth Care among Adults Living with Type 2 Diabetes in Primary Care: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Int J Environ Res Public Health. 2021;18(22):12171. https://doi.org/10.3390/ijerph182212171. source
- Findingown data
All reviews examining diet and physical activity reported that virtual care had a tendency to improve these and other behavioural outcomes.
“all reviews reported that virtual care had a tendency to improve these and other behavioural outcomes.”
Quote in the paperNot a substantial claim2 of 4 sources checked- cites [23] Cassimatis M, Kavanagh DJ. Effects of type 2 diabetes behavioural telehealth interventions on glycaemic control and adherence: a systematic review. J Telemed Telecare. 2012;18(8):447–50. https://doi.org/10.1258/jtt.2012.gth105. source
- cites [35] Wu C, Wu Z, Yang L, Zhu W, Zhang M, Zhu Q, et al. Evaluation of the clinical outcomes of telehealth for managing diabetes: A PRISMA-compliant meta-analysis. Medicine (Baltimore). 2018;97(43):e12962. https://doi.org/10.1097/MD.0000000000012962. source
The Results (Study characteristics; page unavailable) say telehealth interventions offered advice on healthy diet and physical activity and aimed to improve self-management. The paper assesses clinical outcomes, not changes in diet, physical activity, or other behavioural outcomes; the searched passages do not establish the claimed tendency to improve them. (LLM, conf=0.78)
Experimental — accuracy not yet measured - cites [36] van den Berg N, Schumann M, Kraft K, Hoffmann W. Telemedicine and telecare for older patients–a systematic review. Maturitas. 2012;73(2):94–114. https://doi.org/10.1016/j.maturitas.2012.06.010. source
- cites [46] McDaniel CC, Kavookjian J, Whitley HP. Telehealth delivery of motivational interviewing for diabetes management: A systematic review of randomized controlled trials. Patient Educ Couns. 2021;105(4):805–20. https://doi.org/10.1016/j.pec.2021.07.036. source
- Findingcitation
Two reviews found that no single virtual care strategy was superior for reducing HbA1c.
“Two reviews compared different virtual care strategies and found that no single strategy was superior for reducing HbA1c [20, 48].”
Quote in the paperNot a substantial claim2 of 2 sources checked- cites [20] Lee SWH, Chan CKY, Chua SS, Chaiyakunapruk N. Comparative effectiveness of telemedicine strategies on type 2 diabetes management: A systematic review and network meta-analysis. Sci Rep. 2017;7(1):12680. https://doi.org/10.1038/s41598-017-12987-z. source
- cites [48] Robson N, Hosseinzadeh H. Impact of Telehealth Care among Adults Living with Type 2 Diabetes in Primary Care: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Int J Environ Res Public Health. 2021;18(22):12171. https://doi.org/10.3390/ijerph182212171. source
- Findingcitation
Three reviews reported that individualised feedback, either through automated algorithms or health care professionals, improved HbA1c control.
“A further 3 reviews reported that individualised feedback, either through automated algorithms or health care professionals, improved HbA1c control [24, 38, 48].”
Quote in the paperNot a substantial claim2 of 3 sources checked- cites [24] Michaud TL, Ern J, Scoggins D, Su D. Assessing the Impact of Telemonitoring-Facilitated Lifestyle Modifications on Diabetes Outcomes: A Systematic Review and Meta-Analysis. Telemed J E Health. 2021;27(2):124–36. https://doi.org/10.1089/tmj.2019.0319. source
- cites [38] Greenwood DA, Young HM, Quinn CC. Telehealth Remote Monitoring Systematic Review: Structured Self-monitoring of Blood Glucose and Impact on A1C. J Diabetes Sci Technol. 2014;8(2):378–89. https://doi.org/10.1177/1932296813519311. source
- cites [48] Robson N, Hosseinzadeh H. Impact of Telehealth Care among Adults Living with Type 2 Diabetes in Primary Care: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Int J Environ Res Public Health. 2021;18(22):12171. https://doi.org/10.3390/ijerph182212171. source
The Discussion (page not available) reports that telemonitoring interventions with significant HbA1c changes incorporated personalised feedback, and that four mHealth studies with significant reductions shared this feature. It does not establish that the feedback caused the improvement or specify that it was delivered through automated algorithms; the authors frame the broader conclusion as a suggestion. (LLM, conf=0.85)
Experimental — accuracy not yet measured
- Findingcitation
The extracted results for BMI, fasting blood glucose, lipids, blood pressure, and body weight were limited and heterogeneous, making it difficult to draw definitive conclusions about the effectiveness of virtual care on these parameters.
“The extracted results for these outcomes were limited and heterogeneous, making it difficult to draw definitive conclusions about the effectiveness of virtual care on these parameters [40, 45].”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [40] Mushcab H, Kernohan WG, Wallace J, Martin S. Web-Based Remote Monitoring Systems for Self-Managing Type 2 Diabetes: A Systematic Review. Diabetes Technol Ther. 2015;17(7):498–509. https://doi.org/10.1089/dia.2014.0296. source
- cites [45] Hangaard S, Laursen SH, Andersen JD, Kronborg T, Vestergaard P, Hejlesen O, et al. The Effectiveness of Telemedicine Solutions for the Management of Type 2 Diabetes: A Systematic Review, Meta-Analysis, and Meta-Regression. J Diabetes Sci Technol. 2021;17(3):794–825. https://doi.org/10.1177/19322968211064633. source
The Discussion (page not available) says differences in reporting would have left substantial missing baseline blood-pressure and cholesterol data, and it describes considerable heterogeneity among the included studies. The Methods (page not available) specify that the extracted outcomes were HbA1c; the paper does not establish that extracted results for BMI, fasting blood glucose, lipids, blood pressure, and body weight were collectively limited and heterogeneous. (LLM, conf=0.77)
Experimental — accuracy not yet measured
- Study design and conductreasoning
It was not feasible to align the included interventions within a specific framework based on intended purpose and eHealth classification.
“Since all the interventions incorporated management and/or communication systems as integral components of virtual care, it was not feasible to align within a specific framework based on intended purpose and eHealth classification [50].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [50] Rouleau G, Gagnon M-P, Côté J, Payne-Gagnon J, Hudson E, Dubois C-A. Impact of Information and Communication Technologies on Nursing Care: Results of an Overview of Systematic Reviews. J Med Internet Res. 2017;19(4):e122. https://doi.org/10.2196/jmir.6686. source
In Results > Description of the Reviews (page unavailable), the paper says eHealth services may belong to more than one domain, supporting the difficulty of assigning a single classification. It nevertheless classifies the reviewed interventions by eHealth domain; its stated difficulty with a framework concerns categorizing findings about nursing-care impacts, not an inability to align interventions by intended purpose and eHealth classification. (LLM, conf=0.82)
Experimental — accuracy not yet measured
- Rests on an assumption: The diverse virtual care interventions included in the reviews are sufficiently comparable to be synthesised into an overall assessment of virtual care effectiveness.
- Findingcitation
Virtual care programs of at least 6 months were more effective in reducing HbA1c levels compared to programs shorter than 6 months or longer than one year.
“These reviews suggest that virtual care programs of at least 6 months were more effective in terms of reducing HbA1c levels compared to programs shorter than 6 months or longer than one year.”
Quote in the paperSubstantial claim2 of 3 sources checked- cites [29] Su D, Zhou J, Kelley MS, Michaud TL, Siahpush M, Kim J, et al. Does telemedicine improve treatment outcomes for diabetes? A meta-analysis of results from 55 randomized controlled trials. Diabetes Res Clin Pract. 2016;116:136–48. https://doi.org/10.1016/j.diabres.2016.04.019. source
- cites [35] Wu C, Wu Z, Yang L, Zhu W, Zhang M, Zhu Q, et al. Evaluation of the clinical outcomes of telehealth for managing diabetes: A PRISMA-compliant meta-analysis. Medicine (Baltimore). 2018;97(43):e12962. https://doi.org/10.1097/MD.0000000000012962. source
The Discussion says a duration longer than six months could produce larger HbA1c effects, and the Results report that the included interventions lasted 6–12 months. But the paper does not compare those programs with programs longer than one year; its duration-related statement is also tentative, not a finding that 6–12 months was more effective than shorter programs. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites [46] McDaniel CC, Kavookjian J, Whitley HP. Telehealth delivery of motivational interviewing for diabetes management: A systematic review of randomized controlled trials. Patient Educ Couns. 2021;105(4):805–20. https://doi.org/10.1016/j.pec.2021.07.036. source
The Discussion says interventions lasting 6–12 months appeared to foster effects across multiple outcomes, and the Results report HbA1c reductions in 60% of studies assessing it. The paper does not establish that 6–12-month programs reduced HbA1c more effectively than programs shorter than six months or longer than one year. Page numbers are unavailable in our copy. (LLM, conf=0.85)
Experimental — accuracy not yet measured
- Findingcitation
Two reviews reported that virtual care improved medication adherence.
“2 reviews reported that virtual care improved medication adherence [27, 36].”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [27] Hossain MM, Tasnim S, Sharma R, Sultana A, Shaik AF, Faizah F, et al. Digital interventions for people living with non-communicable diseases in India: A systematic review of intervention studies and recommendations for future research and development. Digit Health. 2019;5:2055207619896153. https://doi.org/10.1177/2055207619896153. source
- cites [36] van den Berg N, Schumann M, Kraft K, Hoffmann W. Telemedicine and telecare for older patients–a systematic review. Maturitas. 2012;73(2):94–114. https://doi.org/10.1016/j.maturitas.2012.06.010. source
- Findingcitation
Two of three reviews indicated a positive effect of cost savings due to less travel, wait times and increased access to services.
“Among 3 reviews [25, 32, 34], 2 have indicated a positive effect of cost savings due to less travel, wait times and increased access to services.”
Quote in the paperNot a substantial claim3 of 3 sources checked- cites [25] Zhai YK, Zhu WJ, Cai YL, Sun DX, Zhao J. Clinical- and cost-effectiveness of telemedicine in type 2 diabetes mellitus: a systematic review and meta-analysis. Medicine (Baltimore). 2014;93(28):e312. https://doi.org/10.1097/MD.0000000000000312. source
The Introduction (page unavailable) describes lower costs and greater access as potential benefits of telemedicine. But the Results and Discussion (pages unavailable) report cost data from only two studies and say no conclusion about cost-effectiveness can be drawn. This review does not establish cost savings from reduced travel or waiting times, or identify which two of the three cited reviews reported savings. (LLM, conf=0.82)
Experimental — accuracy not yet measured - cites [32] Eberle C, Stichling S. Effect of Telemetric Interventions on Glycated Hemoglobin A1c and Management of Type 2 Diabetes Mellitus: Systematic Meta-Review. J Med Internet Res. 2021;23(2):e23252. https://doi.org/10.2196/23252. source
The Results sections on combined interventions report lower costs and money saved on physical visits; the real-time video section reports shorter travel and waiting times. The paper does not establish that reduced waiting times or increased access to services caused cost savings, and it cannot substantiate the citing sentence’s count of two out of three reviews. (LLM, conf=0.83)
Experimental — accuracy not yet measured - cites [34] McLendon SF. Interactive Video Telehealth Models to Improve Access to Diabetes Specialty Care and Education in the Rural Setting: A Systematic Review. Diabetes Spectr. 2017;30(2):124–36. https://doi.org/10.2337/ds16-0004. source
The Results > Cost-Benefit Review reports that three of four cost-analysis studies had positive cost-benefit findings, including savings from avoided travel. The Discussion > Benefits of Telehealth in Rural Areas also describes improved access and lower travel costs. Our copy does not establish reduced wait times, and its three-of-four figure does not substantiate the citing sentence’s two-of-three count. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Findingnone given
Significant non-clinical impacts were noted for BMI and secondary outcomes.
“Significant non-clinical impacts were noted for BMI and secondary outcomes.”
Quote in the paperNot a substantial claim - Findingown data
All reviews that analysed HbA1c reported significant reduction of HbA1c for people with diabetes.
“and all reported significant reduction of HbA1c for people with diabetes.”
Quote in the paperSubstantial claim - Findingnone given
Fewer studies addressed other health outcomes such as BMI and taking medications.
“Fewer studies addressed other health outcomes such as BMI and taking medications.”
Quote in the paperNot a substantial claim - Findingown data
About half (16/30) of the systematic reviews covering 681 unique trials were included in the meta-analytic estimate.
“About half (16/30) of the systematic reviews covering 681 unique trials were included in our meta-analytic estimate (Fig. 2).”
Quote in the paperNot a substantial claim - Findingown data
Almost all (28/30) reviews analysed HbA1c as their primary outcome.
“Almost all (28/30) reviews analysed HbA1c as their primary outcome”
Quote in the paperNot a substantial claim - Findingown data
In a sensitivity analysis excluding four reviews that did not provide disaggregated outcomes for type 2 diabetes, the sub-sample of 12 remaining studies with only HbA1c measures for people with type 2 diabetes showed a mean reduction in HbA1c of 0.41% (95% CI: −0.49 to 0.34; I2 = 80.8%).
“Findings from this analysis shows a mean reduction in HbA1c of 0.41% (95% CI: −0.49 to 0.34; I2 = 80.8%)”
Quote in the paperNot a substantial claim - Findingnone given
Overall quality of the included reviews was high.
“Overall quality of the included reviews was high.”
Quote in the paperNot a substantial claim - Findingown data
The studies with video components did not disaggregate the impact of video from other aspects of complex interventions such as web-based and telephone support.
“however these studies did not disaggregate the impact of video from other aspects of complex interventions such as web-based and telephone support.”
Quote in the paperNot a substantial claim - Findingown data
Of the 30 reviews, 28 reported that virtual care improved HbA1c compared to usual care.
“Of the 30 reviews, 28 reported that virtual care improved HbA1c compared to usual care.”
Quote in the paperSubstantial claim - Findingown data
There was significant overlap among the primary studies of the included meta-analyses: of 847 studies, 404 were at least duplicates.
“In addition, we found significant overlap among the primary studies of the included meta-analyses of 847 studies, out of which 404 were at least duplicates.”
Quote in the paperSubstantial claim - Findingown data
Seven out of eight reviews reported a positive effect of virtual care in improving quality of life, self-management or care, and self-efficacy outcomes.
“Seven out of these 8 reviews reported a positive effect in improving these outcomes.”
Quote in the paperSubstantial claim - Findingown data
Six reviews reported non-clinically significant improvements to lipid profile with virtual care.
“Six reviews reported non-clinically significant improvements to lipid profile”
Quote in the paperNot a substantial claim - Findingnone given
Many studies included in the reviews did not specify the isolated effect of a video component on the outcomes.
“However, many studies included in the reviews did not specify the isolated effect of a video component on the outcomes.”
Quote in the paperNot a substantial claim - Findingown data
The majority of reviews (25 out of 30) described studies with a video component such as video consultation, video conferencing or video messages as part of the virtual care interventions and results.
“The majority (25 out of 30 reviews) described studies with a video component such as video consultation, video conferencing or video messages as part of the virtual care interventions and results.”
Quote in the paperNot a substantial claim - Findingown data
Twelve reviews reported a positive tendency on behavioural outcomes with virtual care.
“A total of 12 reviews analysed and reported a positive tendency on behavioural outcomes”
Quote in the paperNot a substantial claim - Findingown data
The meta-analysis showed that virtual care is associated with a statistically significant reduction of 0.37% (0.41% for type 2 diabetes) mean HbA1c compared with standard care in randomised clinical trials.
“Our meta-analysis showed that virtual care is associated with a statistically significant reduction of 0.37% (0.41% for type 2 diabetes) mean HbA1c compared with standard care in randomised clinical trials.”
Quote in the paperSubstantial claim- Rests on an assumption: The 47.7% overlap among primary studies does not invalidate the meta-analysis estimates.
- Rests on an assumption: Reporting bias within the included reviews did not substantially bias the findings.
- Rests on an assumption: Pooling data from mixed diabetes populations does not obscure the true effects specifically for individuals with type 2 diabetes.
- Findingnone given
The review highlights a lack of trials that evaluated interventions using virtual care to provide comprehensive and integrated diabetes management, rather than isolated components.
“Our review also highlights the lack of trials that evaluated interventions that use virtual care to provide comprehensive and integrated diabetes management, rather than isolated components.”
Quote in the paperSubstantial claim - Findingcitation
More frequent interaction by weekly video conferencing showed greater results in reducing HbA1c levels.
“Specifically, more frequent interaction by weekly video conferencing showed greater results in reducing HbA1c levels.”
Quote in the paperNot a substantial claim - Findingcitation
Teleconsultation was found to be more cost-effective than remote monitoring due to various devices and data usage costs.
“In addition, teleconsultation (non-video remote consultations) was found to be more cost-effective than remote monitoring due to various devices and data usage costs [29].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [29] Su D, Zhou J, Kelley MS, Michaud TL, Siahpush M, Kim J, et al. Does telemedicine improve treatment outcomes for diabetes? A meta-analysis of results from 55 randomized controlled trials. Diabetes Res Clin Pract. 2016;116:136–48. https://doi.org/10.1016/j.diabres.2016.04.019. source
- Findingcitation
Virtual care increased older adults' adherence to self-care activities such as blood glucose level checks, diet, exercise, foot and eye checks.
“Virtual care increased older adults’ adherence to self-care activities such as blood glucose Level (BGL) checks, diet, exercise, foot and eye checks [26].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] Marsh Z, Nguyen Y, Teegala Y, Cotter VT. Diabetes management among underserved older adults through telemedicine and community health workers. J Am Assoc Nurse Pract. 2021;34(1):26–31. https://doi.org/10.1097/JXX.0000000000000595. source
- Findingnone given
Some of the included studies did not provide disaggregated outcomes for type 2 diabetes.
“Another limitation of this review is that some of the included studies did not provide disaggregated outcomes for type 2 diabetes.”
Quote in the paperSubstantial claim - Findingcitation
Cost-effectiveness outcomes compared markedly different approaches, revealing a wide variation in costs associated with virtual care.
“Cost-effectiveness outcomes compared markedly different approaches, revealing a wide variation in costs associated with virtual care [26].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] Marsh Z, Nguyen Y, Teegala Y, Cotter VT. Diabetes management among underserved older adults through telemedicine and community health workers. J Am Assoc Nurse Pract. 2021;34(1):26–31. https://doi.org/10.1097/JXX.0000000000000595. source
- Findingcitation
One review reported that short video messages on self-education topics sent to mobile phones every 24 hours were effective, as participants who viewed 10 or more videos showed a 0.6% reduction in HbA1c.
“One review reported that short video messages on self-education topics sent to mobile phones every 24 h were effective, as participants who viewed 10 or more videos showed 0.6% reduction in HbA1c [23].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [23] Cassimatis M, Kavanagh DJ. Effects of type 2 diabetes behavioural telehealth interventions on glycaemic control and adherence: a systematic review. J Telemed Telecare. 2012;18(8):447–50. https://doi.org/10.1258/jtt.2012.gth105. source
- Findingown data
Five reviews reported that telemonitoring was effective compared to usual care.
“Five reviews evaluated telemonitoring compared to usual care and all of them reported that telemonitoring was effective.”
Quote in the paperNot a substantial claim - Findingnone given
All the reviews included a wide range of virtual care interventions, often combining different approaches to support clinical management, such as personalised interactions or feedback between providers and individuals with diabetes.
“All the reviews included a wide range of virtual care interventions, often combining different approaches to support clinical management, such as personalised interactions or feedback between providers and individuals with diabetes.”
Quote in the paperNot a substantial claim- Rests on an assumption: The diverse virtual care interventions included in the reviews are sufficiently comparable to be synthesised into an overall assessment of virtual care effectiveness.
- Interpretationreasoning
Heterogeneity likely reflects differences in type of telehealth interventions, baseline HbA1c levels, duration of follow up, and educational content included in these studies.
“likely reflecting differences in type of telehealth interventions, baseline HbA1c levels, duration of follow up, and educational content included in these studies.”
Quote in the paperNot a substantial claim - Interpretationown data
The mean reduction in HbA1c in the type 2 diabetes sensitivity analysis is similar in direction and effect size to that for all diabetes populations.
“which is similar in direction and effect size for all diabetes populations.”
Quote in the paperNot a substantial claim - Interpretationnone given
Effectiveness of virtual care varies by demographic and clinical characteristics.
“Effectiveness of virtual care varies by demographic and clinical characteristics, emphasising the need to tailor virtual care interventions to maximise impact.”
Quote in the paperNot a substantial claim - Interpretationreasoning
The findings may be biased because they pooled data from mixed diabetes populations, potentially obscuring the true effects specifically for individuals with type 2 diabetes.
“As a result, the findings may be biased, as they have pooled data from mixed type of diabetes populations, potentially obscuring the true effects specifically for individuals with type 2 diabetes.”
Quote in the paperSubstantial claim- Rests on an assumption: Pooling data from mixed diabetes populations does not obscure the true effects specifically for individuals with type 2 diabetes.
- Interpretationreasoning
It remains challenging to draw solid conclusions about the feasibility or compliance with specific types of virtual care.
“While interventions and outcome measures related to remote monitoring, self-management, and educational aspects are frequently evaluated, it remains challenging to draw solid conclusions about the feasibility or compliance with specific types of virtual care.”
Quote in the paperSubstantial claim - Interpretationreasoning
The findings suggest that virtual care is effective in reducing HbA1c levels if it includes blood glucose monitoring and feedback from healthcare professionals.
“The findings suggest that virtual care is effective in reducing HbA1c levels if it includes blood glucose monitoring and feedback from healthcare professionals.”
Quote in the paperSubstantial claim - Interpretationreasoning
Videoconferencing provides a valuable platform for real-time interaction and feedback between people with type 2 diabetes and healthcare providers.
“Videoconferencing provides a valuable platform for real-time interaction and feedback between people with type 2 diabetes and healthcare providers.”
Quote in the paperSubstantial claim - Interpretationreasoning
This umbrella review shows that virtual care has significant potential to improve outcomes in people with type 2 diabetes.
“This umbrella review shows that virtual care has significant potential to improve outcomes in people with type 2 diabetes.”
Quote in the paperSubstantial claim- Rests on an assumption: The diverse virtual care interventions included in the reviews are sufficiently comparable to be synthesised into an overall assessment of virtual care effectiveness.
- Rests on an assumption: The 47.7% overlap among primary studies does not invalidate the meta-analysis estimates.
- Rests on an assumption: Reporting bias within the included reviews did not substantially bias the findings.
- Rests on an assumption: Pooling data from mixed diabetes populations does not obscure the true effects specifically for individuals with type 2 diabetes.
- Interpretationown data
Overall, the comprehensive analysis of 30 systematic reviews and meta-analyses suggests that virtual care can be effective in enhancing clinical and behavioural outcomes in people with type 2 diabetes.
“Overall, this comprehensive analysis of 30 systematic reviews and meta-analyses suggests that virtual care can be effective in enhancing clinical and behavioural outcomes in people with type 2 diabetes.”
Quote in the paperSubstantial claim- Rests on an assumption: The diverse virtual care interventions included in the reviews are sufficiently comparable to be synthesised into an overall assessment of virtual care effectiveness.
- Rests on an assumption: The 47.7% overlap among primary studies does not invalidate the meta-analysis estimates.
- Rests on an assumption: Reporting bias within the included reviews did not substantially bias the findings.
- Rests on an assumption: Pooling data from mixed diabetes populations does not obscure the true effects specifically for individuals with type 2 diabetes.
- Study design and conductown data
Among the 30 systematic reviews assessed, 18 (60%) were deemed high quality with 'YES' for 8 to 11 assessment criteria.
“Among the 30 systematic reviews assessed, 18 (60%) were deemed high quality with ‘YES’ for 8 to 11 assessment criteria.”
Quote in the paperNot a substantial claim - Interpretationcitation
Real-time feedback from health care professionals via video conferencing may be costly compared to automated telehealth interventions.
“Real-time feedback from health care professionals via video conferencing may be costly compared to automated telehealth interventions [24].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [24] Michaud TL, Ern J, Scoggins D, Su D. Assessing the Impact of Telemonitoring-Facilitated Lifestyle Modifications on Diabetes Outcomes: A Systematic Review and Meta-Analysis. Telemed J E Health. 2021;27(2):124–36. https://doi.org/10.1089/tmj.2019.0319. source
- Study design and conductreasoning
Recalculating each study's estimates excluding duplicated studies within was not feasible for the scope of this study.
“Given the enormous number of meta-analyses reviewed in this project, we considered such an analysis was not feasible for the scope of this study.”
Quote in the paperSubstantial claim
- May combine two claims. 41
- Classified as probably not a substantial claim. 30
- The quote only partly states this claim. 1
May combine two claims.
PremisecitationOne recent review analysed the effect of telemedicine across all health conditions, with very few studies focusing on diabetes.
“One recent review [51] analysed the effect of telemedicine across all health conditions, with very few studies focusing on diabetes.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [51] Goharinejad S, Hajesmaeel-Gohari S, Jannati N, Goharinejad S, Bahaadinbeigy K. Review of Systematic Reviews in the Field of Telemedicine. Med J Islam Repub Iran. 2021;35:184. https://doi.org/10.47176/mjiri.35.184. source
The Results (Telemedicine Specialty) support that the review covered multiple telemedicine specialties, but contradict the claim that very few reviews focused on diabetes: tele-diabetes care was the third-largest category, with 18 of 191 reviews (9.4%). The Conclusion also identifies tele-diabetes as one of the areas studied further. (LLM, conf=0.85)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationWith increased and widespread access to internet and smart devices, recent advances in diabetes technology, and rapid changes during the COVID pandemic, virtual care has become more feasible and scalable than ever before.
“With increased and widespread access to internet and smart devices, recent advances in diabetes technology, and rapid changes during the COVID pandemic, virtual care has become more feasible and scalable than ever before [8].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [8] Smith AC, Thomas E, Snoswell CL, Haydon H, Mehrotra A, Clemensen J, et al. Telehealth for global emergencies: Implications for coronavirus disease 2019 (COVID-19). J Telemed Telecare. 2020;26(5):309–13. https://doi.org/10.1177/1357633X20916567. source
The sections on previous emergency use and reimbursement describe telehealth applications during COVID-19 and changes that expanded access to telehealth services. The paper also discusses infrastructure that could be scaled up, but does not attribute greater feasibility to widespread internet or smart-device access or to advances in diabetes technology. It does not establish the comparison “more feasible and scalable than ever before.” No page numbers were provided in our copy. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe systematic review of reviews and meta-analysis was conducted in accordance with the PRISMA 2020 statement.
“This systematic review of reviews and meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) 2020 statement [12].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [12] Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. https://doi.org/10.1136/bmj.n71. source
The Abstract identifies PRISMA 2020 as a reporting guideline for systematic reviews, and the Scope of the guideline says it applies to reviews with meta-analysis. But the Scope explicitly says PRISMA 2020 is not intended to guide systematic review conduct. The source therefore supports citing it as a reporting standard, not as a standard for how the review was conducted. (LLM, conf=0.86)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationThe quality of diabetes care is compromised by time constraints and fragmented care.
“The quality of care is also compromised by time constraints and fragmented care [4].”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [4] Manski-Nankervis JA, Furler J, Blackberry I, Young D, O’Neal D, Patterson E. Roles and relationships between health professionals involved in insulin initiation for people with type 2 diabetes in the general practice setting: a qualitative study drawing on relational coordination theory. BMC Fam Pract. 2014;15(1):20. https://doi.org/10.1186/1471-2296-15-20. source
The Results (Uncertain competency and capacity; page unavailable) identify inadequate time for practice nurses as a safety concern in insulin initiation. The Results (Varying relationships and communication; page unavailable) describe poor communication across providers, and the Conclusion says barriers to coordination may harm patients. These findings support the concern, but the paper focuses on insulin initiation in general practice rather than establishing that time constraints and fragmented care compromise diabetes care generally. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Classified as probably not a substantial claim.
PremisecitationPrevious research suggests that components of virtual care interventions lead to positive outcomes for people with type 2 diabetes such as improved blood glucose control and knowledge to manage their diabetes.
“Previous research suggests that components of virtual care interventions lead to positive outcomes for people with type 2 diabetes such as improved blood glucose control and knowledge to manage their diabetes [9, 10].”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [9] Esmatjes E, Jansa M, Roca D, Perez-Ferre N, del Valle L, Martinez-Hervas S, et al. The efficiency of telemedicine to optimize metabolic control in patients with type 1 diabetes mellitus: Telemed study. Diabetes Technol Ther. 2014;16(7):435–41. https://doi.org/10.1089/dia.2013.0313. source
The Clinical evolution section (page not provided) reports improved HbA1c and diabetes-knowledge scores in the telemedicine group, but the participants had type 1 diabetes, not type 2. Both the telemedicine and face-to-face groups improved, so the study does not establish that a particular virtual-care component caused the gains. (LLM, conf=0.90)
Experimental — accuracy not yet measured - cites [10] Gonzalez-Molero I, Dominguez-Lopez M, Guerrero M, Carreira M, Caballero F, Rubio-Martin E, et al. Use of telemedicine in subjects with type 1 diabetes equipped with an insulin pump and real-time continuous glucose monitoring. J Telemed Telecare. 2012;18(6):328–32. https://doi.org/10.1258/jtt.2012.120103. source
May combine two claims.
Findingown dataOnly one study included in the BMI meta-analysis reported the BMI measure for type 2 diabetes, and all other three reviews included combined results for mixed type of diabetes.
“Only one study [44] included in this analysis reported the BMI measure for type 2 diabetes and all other three reviews included combined results for mixed type of diabetes.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [44] De Groot J, Wu D, Flynn D, Robertson D, Grant G, Sun J. Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes: A meta-analysis. World J Diabetes. 2021;12(2):170–97. https://doi.org/10.4239/wjd.v12.i2.170. source
May combine two claims.
Findingown dataThe findings suggest that virtual care had a greater impact on older people with type 2 diabetes over 50 years of age in managing their diabetes effectively, which contradicts another umbrella review that reported virtual care had a greater effect on younger people with type 2 diabetes aged 41 to 50 years.
“Our findings from this review suggest that virtual care had a greater impact on older people with type 2 diabetes over 50 years of age in managing their diabetes effectively, which contradicts another umbrella review that reported virtual care had a greater effect on younger people with type 2 diabetes aged 41 to 50 years [53].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [53] Timpel P, Oswald S, Schwarz PEH, Harst L. Mapping the Evidence on the Effectiveness of Telemedicine Interventions in Diabetes, Dyslipidemia, and Hypertension: An Umbrella Review of Systematic Reviews and Meta-Analyses. J Med Internet Res. 2020;22(3):e16791. https://doi.org/10.2196/16791. source
Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing).
FindingcitationOne review concluded that interactive video telehealth technologies might be effective in enhancing access to quality care, patient empowerment and self-care management.
“One review concluded that interactive video telehealth technologies might be effective in enhancing access to quality care, contribute to patient empowerment and self-care management [34].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [34] McLendon SF. Interactive Video Telehealth Models to Improve Access to Diabetes Specialty Care and Education in the Rural Setting: A Systematic Review. Diabetes Spectr. 2017;30(2):124–36. https://doi.org/10.2337/ds16-0004. source
May combine two claims.
FindingcitationInterventions between 6 and 12 months were described as more effective because the benefits of virtual care may occur in the first few months or become more difficult to implement robustly and keep people with type 2 diabetes engaged over the longer term.
“Interventions between 6 and 12 month were described as more effective because the benefits of virtual care may occur in the first few months or become more difficult to implement robustly and keep people with type 2 diabetes engaged over the longer term [37].”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [37] Marcolino MS, Maia JX, Alkmim MB, Boersma E, Ribeiro AL. Telemedicine application in the care of diabetes patients: systematic review and meta-analysis. PLoS ONE. 2013;8(11):e79246. https://doi.org/10.1371/journal.pone.0079246. source
Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing).
InterpretationcitationThis is consistent with previous research on telehealth remote monitoring using Self-Monitoring of Blood Glucose transmission devices.
“This is consistent with previous research on telehealth remote monitoring using Self-Monitoring of Blood Glucose (SMBG) transmission devices [52, 53].”
Quote in the paperNot a substantial claim2 of 2 sources checked- cites [52] Lee PA, Greenfield G, Pappas Y. The impact of telehealth remote patient monitoring on glycemic control in type 2 diabetes: a systematic review and meta-analysis of systematic reviews of randomised controlled trials. BMC Health Serv Res. 2018;18(1):495. https://doi.org/10.1186/s12913-018-3274-8. source
- cites [53] Timpel P, Oswald S, Schwarz PEH, Harst L. Mapping the Evidence on the Effectiveness of Telemedicine Interventions in Diabetes, Dyslipidemia, and Hypertension: An Umbrella Review of Systematic Reviews and Meta-Analyses. J Med Internet Res. 2020;22(3):e16791. https://doi.org/10.2196/16791. source
The Discussion (Principal Findings; page not available) reports evidence that telemonitoring combined with tele-case management reduced HbA1c in patients with type 2 diabetes. It does not identify Self-Monitoring of Blood Glucose transmission devices as the technology used, so it supports the broader remote-monitoring point but not that specific device description. (LLM, conf=0.81)
Experimental — accuracy not yet measured
May combine two claims.
InterpretationcitationMessages generated using automated algorithms may offer a more feasible and less expensive solution.
“Messages generated using automated algorithms may offer a more feasible and less expensive solution [31].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [31] Faruque LI, Wiebe N, Ehteshami-Afshar A, Liu Y, Dianati-Maleki N, Hemmelgarn BR, et al. Effect of telemedicine on glycated hemoglobin in diabetes: a systematic review and meta-analysis of randomized trials. CMAJ. 2017;189(9):E341–64. https://doi.org/10.1503/cmaj.150885. source
May combine two claims.
Findingown dataFour reviews were included for meta-analyses of BMI and there was no statistically significant difference in BMI between virtual care interventions and usual care, with a reduction of 0.13 (95% CI: −0.28 to 0.03; I2 = 25.5%).
“Four reviews were included for meta-analyses and there was no statistically significant difference of BMI between virtual care interventions and usual care, with only a reduction of 0.13 [95% CI: −0.28 to 0.03; I2 = 25.5%] (Fig. 4).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataThe search strategy identified 30 systematic reviews, of which 18 included a meta-analysis, and one included a network meta-analysis.
“The search strategy identified 30 systematic reviews, of which 18 included a meta-analysis, and one included a network meta-analysis.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataIncluded systematic reviews were published between 2012 and 2022, with 24 (80%) reporting fewer than 50 studies, 3 between 50-100, and 3 more than 100 studies.
“Included systematic reviews were published between 2012 and 2022, with the majority (n = 24; 80%) reporting fewer than 50 studies, 3 articles between 50–100 and 3 articles with more than 100 studies.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataOf the six databases searched, 10,708 citations were identified and transferred to Covidence, which removed 4,629 duplicates.
“Of the six databases searched, a total of 10,708 citations were identified and transferred to Covidence, which removed 4,629 duplicates.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataExclusion of Michaud 2021 in sensitivity analysis did not significantly alter the results or heterogeneity, with MD −0.38% (95% CI: −0.44 to 0.32, I2 = 71.8).
“Exclusion of this review did not significantly alter the results or heterogeneity [MD −0.38% (95% CI: −0.44 to 0.32, I2 = 71.8)].”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataOne review, Michaud 2021, contributed an unexpectedly high weighting on the initial analysis because of its narrow CI bounds.
“One review, Michaud 2021 [24], contributed an unexpectedly high weighting on the initial analysis because of its narrow CI bounds.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [24] Michaud TL, Ern J, Scoggins D, Su D. Assessing the Impact of Telemonitoring-Facilitated Lifestyle Modifications on Diabetes Outcomes: A Systematic Review and Meta-Analysis. Telemed J E Health. 2021;27(2):124–36. https://doi.org/10.1089/tmj.2019.0319. source
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataMost reviews (25/30) included some studies with video components.
“Most reviews (25/30) included some studies with video components”
- Also stated in: § Characteristics of the included reviews (Table 1) · plain
“Twenty five out of 30 reviews included a minority of studies with video components, such as video consultation, video conferencing or video messages as part of the virtual care interventions.”
Quote in the paperNot a substantial claim- Also stated in: § Characteristics of the included reviews (Table 1) · plain
May combine two claims.
Findingown dataThe full text review resulted in 63 studies that included 30 systematic reviews, 3 review of reviews, 23 RCTs, and 7 qualitative studies.
“The full text review resulted in a total of 63 studies that included 30 systematic reviews, 3 review of reviews, 23 RCTs, and 7 qualitative studies.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataMeta-analysis of 16 reviews revealed a mean difference in HbA1c of -0.37% (95% CI -0.41% to -0.32%), with I2 of 77.1%.
“Meta-analysis of 16 reviews revealed a mean difference of -0.37% (-0.41% to -0.32%), I2 of 77.1%.”
- Also stated in: § Clinical outcomes · plain
“The mean reduction in HbA1c was 0.37% (95% CI: −0.41% to −0.32%).”
- Also stated in: § Clinical outcomes · plain
“Heterogeneity was high, with an I2 of 77.1%”
Quote in the paperSubstantial claim- Also stated in: § Clinical outcomes · plain
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataAfter title and abstract screening, 85 studies were obtained for full text assessment.
“After title and abstract screening, a total of 85 studies were obtained for full text assessment.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThree reviews included diabetes and other conditions but did not specify the type of diabetes.
“Three reviews included diabetes and other conditions but did not specify the type of diabetes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe reviews covered 68 countries in 6 continents.
“The reviews covered 68 countries in 6 continents.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataEight out of thirty reviews described the effect of virtual care on BMI as a secondary outcome measure.
“Eight out of thirty reviews described the effect of virtual care on BMI as a secondary outcome measure.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe number of participants ranged from 10 to 23,648 in individual studies.
“The number of participants ranged from 10 to 23,648 in individual studies.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataFour out of 14 reviews with mixed populations reported findings separately for people with type 2 diabetes.
“Four out of 14 reviews reported findings separately for people with type 2 diabetes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataOf the 30 reviews, 13 focused exclusively on populations with type 2 diabetes, while 14 included mixed populations consisting of type 2 and/or type 1, gestational diabetes, and pre-diabetes.
“Of the 30 reviews, 13 focused exclusively on populations with type 2 diabetes, while 14 included mixed populations, consisting of individuals with type 2 diabetes, and/or type 1, gestational diabetes, and pre-diabetes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataOf the 85 studies, 22 were removed.
“Of these studies, a further 22 studies were removed (see Fig. 1).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataAmong the 30 systematic reviews, there was significant overlap of the primary studies, with 48% of them appearing in multiple reviews.
“Among the 30 systematic reviews, there was significant overlap of the primary studies, with 48% of them appearing in multiple reviews.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingcitationOne review suggested that any evaluation less than 3 months would not be sufficient because of the time required to educate people with type 2 diabetes with virtual care systems or devices.
“One review suggested that any evaluation less than 3 months would not be sufficient because of the time required to educate people with type 2 diabetes with virtual care systems or devices [30].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [30] Hu Y, Wen X, Wang F, Yang D, Liu S, Li P, et al. Effect of telemedicine intervention on hypoglycaemia in diabetes patients: A systematic review and meta-analysis of randomised controlled trials. J Telemed Telecare. 2019;25(7):402–13. https://doi.org/10.1177/1357633X18776823. source
Probably not a substantial claim: may not pass S3 (load-bearing).
FindingcitationOne review reported that virtual care was effective in enhancing patient-provider interactions.
“one review [26] reported virtual care was effective in enhancing patient-provider interactions.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] Marsh Z, Nguyen Y, Teegala Y, Cotter VT. Diabetes management among underserved older adults through telemedicine and community health workers. J Am Assoc Nurse Pract. 2021;34(1):26–31. https://doi.org/10.1097/JXX.0000000000000595. source
May combine two claims.
Findingown dataVirtual care showed mixed effects on BMI, fasting blood glucose, lipids, blood pressure, and body weight, but these were not statistically or clinically significant.
“Consistent with previous findings, virtual care showed mixed effects on BMI, fasting blood glucose, lipids, blood pressure, and body weight, but these were not statistically or clinically significant.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataResults of the study indicated that virtual care improved behavioural outcomes, including improvements in treatment and medication adherence, self-efficacy, and quality of life.
“Results of our study also indicated that virtual care improved behavioural outcomes, including improvements in treatment and medication adherence, self-efficacy, and quality of life.”
Quote in the paperSubstantial claim- Rests on an assumption: The diverse virtual care interventions included in the reviews are sufficiently comparable to be synthesised into an overall assessment of virtual care effectiveness.
May combine two claims.
Findingown dataFour reviews showed reduction in body weight or improved weight loss with virtual care, but not statistically significant.
“four reviews showed reduction in body weight or improved weight loss, but not statistically significant.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationVirtual care interventions had a greater effect among adults aged 50 years or older, with better treatment outcomes compared to younger adults, as reported in five reviews.
“Virtual care interventions were found to have greater effect among adults who were 50 years or older, with better treatment outcomes compared to younger adults reported in 5 reviews [21, 22, 26, 29, 36].”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [21] Tchero H, Kangambega P, Briatte C, Brunet-Houdard S, Retali GR, Rusch E. Clinical Effectiveness of Telemedicine in Diabetes Mellitus: A Meta-Analysis of 42 Randomized Controlled Trials. Telemed J E Health. 2019;25(7):569–83. https://doi.org/10.1089/tmj.2018.0128. source
- cites [22] Kaveh MH, Faradonbeh MR, Kaveh S. Telehealth impact on biomedical, psychosocial, and behavioural outcomes in patients with diabetes older than 50 years: A systematic synthesis without meta-analysis. J Telemed Telecare. 2024;30(2):285–304. https://doi.org/10.1177/1357633X211052222. source
- cites [26] Marsh Z, Nguyen Y, Teegala Y, Cotter VT. Diabetes management among underserved older adults through telemedicine and community health workers. J Am Assoc Nurse Pract. 2021;34(1):26–31. https://doi.org/10.1097/JXX.0000000000000595. source
May combine two claims.
Findingnone givenThe study includes 15 systematic reviews that were not included in 3 previous umbrella reviews, including 11 systematic reviews published in the emergency phase of the COVID-19 pandemic.
“Our study includes 15 systematic reviews that were not included in 3 previous umbrella reviews, including 11 systematic reviews published in the emergency phase of the COVID-19 pandemic, which accelerated virtual care due to lockdowns.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataTwo investigators independently conducted data extraction from the final selected studies and disagreements were resolved through discussion.
“Two investigators (SR and CY) then independently conducted data extraction from the final selected studies using the agreed-upon form. The extracted data were compared and any disagreements resolved through discussion.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataTwo independent investigators screened titles and abstracts and resolved disagreements.
“Two independent investigators (SR and GMK) screened the titles and abstracts on Covidence according to the criteria described above to determine the eligibility for inclusion and compared the lists to resolve any disagreements.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationConsistent engagement between people with type 2 diabetes and healthcare professionals for ongoing support for diabetes management and self-care helps to prevent diabetes related complications and improves quality of life.
“Such consistent engagement between people with type 2 diabetes and healthcare professionals for ongoing support for diabetes management and self-care helps to prevent diabetes related complications and improves quality of life [2].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [2] American Diabetes Association Professional Practice C. 6. Glycemic Goals and Hypoglycemia: Standards of Care in Diabetes-2024. Diabetes Care. 2024;47(Suppl 1):S111-S25. https://doi.org/10.2337/dc24-S006.1/16/2024. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataTwo independent investigators reviewed full texts to establish a final list of studies, with discrepancies resolved by consulting third and fourth investigators.
“The two investigators (SR and GMK) then independently reviewed the full text of selected studies to establish a final list of studies. Any discrepancies were resolved by consulting with the third and fourth investigators (CB and JA).”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataThis umbrella review strengthens the evidence that virtual care significantly improves clinical outcomes in people with type 2 diabetes, primarily affecting HbA1c.
“This umbrella review strengthens the evidence that virtual care significantly improves clinical outcomes in people with type 2 diabetes, primarily affecting HbA1c.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe data extraction form was piloted using two review articles and discussed to reach agreement.
“The extraction form was piloted by SR using two review articles. The pilot process and extracted information were discussed with CB and JA to reach an agreement on the form.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationVirtual care has advantages such as easier access, minimal wait times, no travel to clinics, and therefore less expensive diabetes care.
“Though face-to-face care will always have a role, virtual care has several advantages such as easier access, minimal wait times and no travel to clinics, therefore less expensive diabetes care [5].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [5] Iyengar V, Wolf A, Brown A, Close K. Challenges in Diabetes Care: Can Digital Health Help Address Them? Clin Diabetes. 2016;34(3):133–41. https://doi.org/10.2337/diaclin.34.3.133.1/9/2024. source
Not checked in the free run.
May combine two claims.
PremisecitationVisiting a health care team can be costly and time-consuming for people with type 2 diabetes, and most people with type 2 diabetes do not see their health professionals enough.
“Visiting a health care team can be costly and time-consuming for people with type 2 diabetes, with evidence suggesting most people with type 2 diabetes do not see their health professionals enough [3].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [3] Nam S, Chesla C, Stotts NA, Kroon L, Janson SL. Barriers to diabetes management: patient and provider factors. Diabetes Res Clin Pract. 2011;93(1):1–9. https://doi.org/10.1016/j.diabres.2011.02.002. source
Classified as probably not a substantial claim.
Study design and conductown dataMethodological quality was assessed independently by two reviewers using the JBI Critical Appraisal Checklist for Systematic Reviews and Research Synthesis.
“Assessment of the methodological quality was completed by two reviewers (SR and GMK) independently on all selected articles included in the systematic review using the Joanna Briggs Institute’s (JBI) Critical Appraisal Checklist for Systematic Reviews and Research Synthesis [16].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [16] Aromataris E, Fernandez R, Godfrey CM, Holly C, Khalil H, Tungpunkom P. Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach. Int J Evid Based Healthc. 2015;13(3):132–40. https://doi.org/10.1097/XEB.0000000000000055. source
May combine two claims.
PremisecitationHbA1c is recognised as a valuable indicator of treatment effectiveness in people with type 2 diabetes because it reflects average glycemia over several months and is strongly correlated with diabetes complications.
“HbA1c is recognised as a valuable indicator of treatment effectiveness in people with type 2 diabetes [2], because it reflects average glycemia over several months and is strongly correlated with diabetes complications [2, 18, 19].”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [2] American Diabetes Association Professional Practice C. 6. Glycemic Goals and Hypoglycemia: Standards of Care in Diabetes-2024. Diabetes Care. 2024;47(Suppl 1):S111-S25. https://doi.org/10.2337/dc24-S006.1/16/2024. source
Not checked in the free run.
- cites [18] Nathan DM, Genuth S, Lachin J, Cleary P, et al. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329(14):977–86. https://doi.org/10.1056/NEJM199309303291401. source
- cites [19] Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000;321(7258):405–12. https://doi.org/10.1136/bmj.321.7258.405. source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe protocol was registered with PROSPERO (CRD42022366125) in October 2022.
“The protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO CRD42022366125) in October 2022 [13].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [13] Ravi S, Meyerowitz-Katz G, Ayre J, McCaffery K, Maberly G, Bonner C. Virtual Care for type 2 diabetes: definitions, implementation and effectiveness compared to usual care. PROSPERO 2022 CRD42022366125. 2022. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022366125.
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Study design and conductnone givenIt is possible that reporting bias within the included reviews could have impacted which studies were included, which may have also biased the findings.
“In addition, it is possible that reporting bias within the included reviews could have impacted which studies were included, which may have also biased our findings.”
Quote in the paperNot a substantial claim- Rests on an assumption: Reporting bias within the included reviews did not substantially bias the findings.
May combine two claims.
Interpretationown dataThe 47.7% overlap affects the accuracy of the meta-analysis estimates, as it represents a significant portion of the research that would have been duplicated in the meta-analysis.
“This 47.7% overlap affects the accuracy of our meta-analysis estimates, as it represents a significant portion of the research would have been duplicated in our meta-analysis.”
Quote in the paperNot a substantial claim- Rests on an assumption: The 47.7% overlap among primary studies does not invalidate the meta-analysis estimates.
May combine two claims.
Interpretationown dataThe current study shows that whilst virtual care may not be universally beneficial for health outcomes, it does seem to play a specific and significant role in the context of diabetes.
“Our current study shows that whilst virtual care may not be universally beneficial for health outcomes, it does seem to play a specific and significant role in the context of diabetes.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationFor people with type 2 diabetes, reducing the mean HbA1c level by 1% would be related to a 21% reduction in diabetes-related death and a 37% reduction in microvascular complications such as neuropathy, retinopathy, and blindness.
“For people with type 2 diabetes, reducing the mean HbA1c level by 1% would be related to a 21% reduction in diabetes-related death and a 37% reduction in microvascular complications, such as neuropathy, retinopathy, and blindness [19].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [19] Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000;321(7258):405–12. https://doi.org/10.1136/bmj.321.7258.405. source
May combine two claims.
InterpretationcitationVirtual care may be particularly effective for older adults aged 50 and above and for people with type 2 diabetes with higher baseline HbA1c levels.
“Virtual care may be particularly effective for older adults, especially those aged 50 and above [23, 29], and for people with type 2 diabetes with higher baseline HbA1c levels [33].”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [23] Cassimatis M, Kavanagh DJ. Effects of type 2 diabetes behavioural telehealth interventions on glycaemic control and adherence: a systematic review. J Telemed Telecare. 2012;18(8):447–50. https://doi.org/10.1258/jtt.2012.gth105. source
- cites [29] Su D, Zhou J, Kelley MS, Michaud TL, Siahpush M, Kim J, et al. Does telemedicine improve treatment outcomes for diabetes? A meta-analysis of results from 55 randomized controlled trials. Diabetes Res Clin Pract. 2016;116:136–48. https://doi.org/10.1016/j.diabres.2016.04.019. source
- cites [33] Huang Z, Tao H, Meng Q, Jing L. Management of endocrine disease. Effects of telecare intervention on glycemic control in type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Eur J Endocrinol. 2015;172(3):R93-101. https://doi.org/10.1530/EJE-14-0441. source
May combine two claims.
Study design and conductreasoningThe overlap number was included as a potential limitation that may have impacted the estimates, but it was not mitigated in the analysis.
“Therefore, we included this overlap number as a potential limitation that may have impacted the estimates, but we have not mitigated it as such in our analysis.”
Quote in the paperNot a substantial claim- Rests on an assumption: The 47.7% overlap among primary studies does not invalidate the meta-analysis estimates.
Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).
Study design and conductnone givenIn this review robust methods were used to generate high-quality evidence on the effects of virtual care in diabetes management.
“In this review robust methods were used to generate high-quality evidence on the effects of virtual care in diabetes management.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductreasoningMeSH terms were not used to avoid missing relevant articles because complex interventions with video components did not align well with established search terms.
“As we aimed to capture complex interventions with video components, which did not align well with established search terms, MeSH terms were, therefore not used to avoid missing relevant articles.”
Quote in the paperNot a substantial claimMay combine two claims. The quote only partly states this claim.
InterpretationreasoningEvidence from systematic reviews and meta-analyses demonstrates the effectiveness of virtual care interventions for clinical outcomes, with mixed evidence for behavioural outcomes.
“Evidence from systematic reviews and meta-analyses demonstrates the effectiveness of virtual care interventions for clinical outcomes, with mixed evidence for behavioural outcomes.”
Quote in the paperSubstantial claimMay combine two claims.
InterpretationreasoningThe effectiveness of virtual care interventions varies based on demographic and clinical characteristics, highlighting the importance of customising these interventions to maximise their impact.
“The effectiveness of virtual care interventions varies based on demographic and clinical characteristics, highlighting the importance of customising these interventions to maximise their impact.”
Quote in the paperSubstantial claimMay combine two claims.
InterpretationreasoningThe use of SMS text messaging could be an effective and cost-efficient way to communicate and motivate people with type 2 diabetes, potentially leading to positive outcomes.
“The use of SMS text messaging could be an effective and cost-efficient way to communicate and motivate people with type 2 diabetes, potentially leading to positive outcomes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).
Interpretationnone givenThis limitation applies across the literature and is a fundamental problem with meta-syntheses of this type.
“This limitation applies across the literature and is a fundamental problem with meta-syntheses of this type.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductreasoningA comprehensive and piloted search strategy was developed using a broad set of keywords, but some relevant studies may have been missed.
“Although a comprehensive and piloted search strategy was developed using the broad set of keywords, it is possible that some relevant studies would have been missed.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
There is limited evidence evaluating current integrated virtual care interventions in diabetes management, including more recent video conferencing technology.
“However, with the recent rapid shift to virtual care, there is still limited evidence when it comes to the evaluation of current integrated virtual care interventions in diabetes management, including more recent video conferencing technology.”
The paper relies on this without support.
The diverse virtual care interventions included in the reviews are sufficiently comparable to be synthesised into an overall assessment of virtual care effectiveness.
“All the reviews included a wide range of virtual care interventions, often combining different approaches to support clinical management, such as personalised interactions or feedback between providers and individuals with diabetes.”
“Since all the interventions incorporated management and/or communication systems as integral components of virtual care, it was not feasible to align within a specific framework based on intended purpose and eHealth classification [50].”
The paper relies on this without support.
The 47.7% overlap among primary studies does not invalidate the meta-analysis estimates.
“This 47.7% overlap affects the accuracy of our meta-analysis estimates, as it represents a significant portion of the research would have been duplicated in our meta-analysis.”
“Therefore, we included this overlap number as a potential limitation that may have impacted the estimates, but we have not mitigated it as such in our analysis.”
The paper relies on this without support.
Reporting bias within the included reviews did not substantially bias the findings.
“In addition, it is possible that reporting bias within the included reviews could have impacted which studies were included, which may have also biased our findings.”
The paper relies on this without support.
Pooling data from mixed diabetes populations does not obscure the true effects specifically for individuals with type 2 diabetes.
“As a result, the findings may be biased, as they have pooled data from mixed type of diabetes populations, potentially obscuring the true effects specifically for individuals with type 2 diabetes.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Intervention-duration summary conflicts with Su review
MajorThe timeframe section says the cited reviews favour programs of at least six months over shorter programs. Table 1 instead says Su [29] found interventions of six months or less more effective than longer programs.
“These reviews suggest that virtual care programs of at least 6 months were more effective in terms of reducing HbA1c levels compared to programs shorter than 6 months or longer than one year.”
“Su D (2016) [29] | Either type 1 or type 2 or both | 49 | Significant reduction of HbA1c pre and post-tests varied from 2.2% to 0.5% in intervention groups and from 1.3% to 0.6% in control groups; n = 55 | Most effective for type 2 diabetes than type 1 and among people with diabetes of ages 40 or older. Interventions of 6 months or less showed greater effect than longer programs”
Abstract claims a significant BMI impact contrary to the BMI analysis
MajorThe abstract reports a significant impact on BMI, while the BMI meta-analysis explicitly reports no statistically significant difference.
“Significant non-clinical impacts were noted for BMI and secondary outcomes.”
“there was no statistically significant difference of BMI between virtual care interventions and usual care, with only a reduction of 0.13 [95% CI: −0.28 to 0.03; I2 = 25.5%]”
Correia video estimate lies outside its reported confidence interval
MajorThe reported mean difference of −0.89% is below the reported confidence interval's lower bound of −0.85%.
“with mean difference of −0.89%”
“(95% CI: −0.85 to 0.08)”
Robson HbA1c interval conflicts with claimed significance
MinorThe reported confidence interval extends from a positive value to a negative value and therefore includes zero, despite the row calling the reduction significant.
“Significant reduction of HbA1c MD −0.18%”
“(95% CI: 0.35% to −0.01%) n = 21”
Appraisal percentage uses the wrong denominator
MinorThe text says "Of those" 22 reviews, 12 had at least two appraisers. That is 54.5%, not 40.0%; 40.0% uses all 30 reviews as the denominator.
Reported 40 · recomputed 54.545455
“22 reviews (73.3%) assessed the methodological quality of included reviews. Of those, 12 (40.0%) reported that at least two reviewers performed the appraisal.”
Blood-pressure summary conflicts with Marcolino review
MinorThe results say all seven listed reviews, including Marcolino [37], reported reduced blood pressure. Table 1 says Marcolino found no effect on blood pressure.
“all 7 reviews [22, 27, 32, 35, 37, 44, 46] reported reduction in blood pressure.”
“Marcolino M S (2013) [37] | Type 1 or type 2 | 15 | Significant reduction of HbA1c MD −0.44% (95% CI: −0.61% to −0.26%) n = 13 | Reduction in LDL-cholesterol, no effect on blood pressure and tendency to reduce BMI”
Hu BMI estimate lies outside its reported confidence interval
MinorThe reported BMI mean difference of −0.27 lies outside the stated interval of −0.86 to −0.31. The interval also conflicts with the row's statement that the effect was not significant.
“No significant effect on BMI. MD −0.27;”
“(95% CI:−0.86% to −0.31%); n = 7”
Type 2 diabetes result is called statistically significant despite a CI spanning zero
MinorThe discussion calls the 0.41% type 2 diabetes reduction statistically significant, but the reported confidence interval for that estimate runs from −0.49 to 0.34 and includes zero.
“Our meta-analysis showed that virtual care is associated with a statistically significant reduction of 0.37% (0.41% for type 2 diabetes) mean HbA1c compared with standard care in randomised clinical trials.”
“Findings from this analysis shows a mean reduction in HbA1c of 0.41% (95% CI: −0.49 to 0.34; I2 = 80.8%)”
Cites
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“HbA1c is recognised as a valuable indicator of treatment effectiveness in people with type 2 diabetes [2], because it reflects average glycemia over several months and is strongly correlated with diabetes complications [2, 18, 19].”
International Diabetes Federation 2017
Carracher, A. M., Marathe, P. H., & Close, K. L. (2018) · Journal of Diabetes · doi:10.1111/1753-0407.12644 · Cited by 13,369 · see citing works
Stratton, I. M. (2000) · BMJ · doi:10.1136/bmj.321.7258.405 · Cited by 9,059 · cited 2× · see citing works
“For people with type 2 diabetes, reducing the mean HbA1c level by 1% would be related to a 21% reduction in diabetes-related death and a 37% reduction in microvascular complications, such as neuropathy, retinopathy, and blindness [19].”
Aromataris, E., Fernandez, R., Godfrey, C. M., Holly, C., Khalil, H., & Tungpunkom, P. (2015) · International Journal of Evidence-Based Healthcare · doi:10.1097/xeb.0000000000000055 · Cited by 2,587 · cited 1× · see citing works
“Assessment of the methodological quality was completed by two reviewers (SR and GMK) independently on all selected articles included in the systematic review using the Joanna Briggs Institute’s (JBI) Critical Appraisal Checklist for Systematic Reviews and Research Synthesis [16].”
Telehealth for global emergencies: Implications for coronavirus disease 2019 (COVID-19)
Smith, A. C., Thomas, E., Snoswell, C. L., Haydon, H., Mehrotra, A., Clemensen, J., & Caffery, L. J. (2020) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x20916567 · Cited by 1,828 · cited 1× · see citing works
“With increased and widespread access to internet and smart devices, recent advances in diabetes technology, and rapid changes during the COVID pandemic, virtual care has become more feasible and scalable than ever before [8].”
Barriers to diabetes management: patient and provider factors
Nam, S., Chesla, C., Stotts, N. A., Kroon, L., & Janson, S. L. (2011) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2011.02.002 · Cited by 680 · cited 1× · see citing works
“Visiting a health care team can be costly and time-consuming for people with type 2 diabetes, with evidence suggesting most people with type 2 diabetes do not see their health professionals enough [3].”
Disparities in Health Care and the Digital Divide
Saeed, S. A., & Masters, R. M. (2021) · Current Psychiatry Reports · doi:10.1007/s11920-021-01274-4 · Cited by 578 · see citing works
6. Glycemic Goals and Hypoglycemia: Standards of Care in Diabetes—2024
ElSayed, N. A., Aleppo, G., Bannuru, R. R., Bruemmer, D., Collins, B. S., Ekhlaspour, L., Hilliard, M. E., Johnson, E. L., Khunti, K., Lingvay, I., et al. (2023) · Diabetes Care · doi:10.2337/dc24-s006 · Cited by 541 · see citing works
Personalized Telehealth in the Future: A Global Research Agenda
Dinesen, B., Nonnecke, B. M., Lindeman, D. A., Toft, E. S., Kidholm, K., Jethwani, K., Young, H. M., Spindler, H., Oestergaard, C. U., Southard, J. A., et al. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5257 · Cited by 300 · cited 1× · see citing works
“Virtual Care (VC) models incorporate telehealth and virtual interactions between provider-patient and provider-provider by video, telephone, and secure messaging such as mobile and web-based applications [7].”
Faruque, L. I., Wiebe, N., Ehteshami-Afshar, A., Liu, Y., Dianati-Maleki, N., Hemmelgarn, B. R., Manns, B. J., & Tonelli, M. (2017) · Canadian Medical Association Journal · doi:10.1503/cmaj.150885 · Cited by 281 · cited 4× · see citing works
“There were 5 reviews evaluating virtual care components; 3 reviews [28, 31, 43] reported that interventions as simple as text-messaging or SMS feedback were equally effective in improving HbA1c, compared to a teleconference or telephone appointment with healthcare professionals.”
InfluentialTelemedicine and telecare for older patients—A systematic review
van den Berg, N., Schumann, M., Kraft, K., & Hoffmann, W. (2012) · Maturitas · doi:10.1016/j.maturitas.2012.06.010 · Cited by 251 · see citing works
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“Since all the interventions incorporated management and/ or communication systems as integral components of virtual care, it was not feasible to align within a specific framework based on intended purpose and eHealth classification [50].”
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Tchero, H., Kangambega, P., Briatte, C., Brunet-Houdard, S., Retali, G.-R., & Rusch, E. (2019) · Telemedicine and e-Health · doi:10.1089/tmj.2018.0128 · Cited by 239 · cited 2× · see citing works
“Virtual care interventions were found to have greater effect among adults who were 50 years or older, with better treatment outcomes compared to younger adults reported in 5 reviews [21, 22, 26, 29, 36].”
Zhai, Y.-K., Zhu, W.-J., Cai, Y.-L., Sun, D.-X., & Zhao, J. (2014) · Medicine · doi:10.1097/md.0000000000000312 · Cited by 221 · cited 1× · see citing works
“Among 3 reviews [25, 32, 34], 2 have indicated a positive effect of cost savings due to less travel, wait times and increased access to services.”
Telemedicine Application in the Care of Diabetes Patients: Systematic Review and Meta-Analysis
Marcolino, M. S., Maia, J. X., Alkmim, M. B. M., Boersma, E., & Ribeiro, A. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079246 · Cited by 215 · cited 3× · see citing works
“While four reviews [26, 27, 37, 43] assessed if virtual care was effective in facilitating feedback and interactions between people with diabetes and healthcare professionals, one review [26] reported virtual care was effective in enhancing patient-provider interactions.”
Lee, S. W. H., Chan, C. K. Y., Chua, S. S., & Chaiyakunapruk, N. (2017) · Scientific Reports · doi:10.1038/s41598-017-12987-z · Cited by 200 · see citing works
Su, D., Zhou, J., Kelley, M. S., Michaud, T. L., Siahpush, M., Kim, J., Wilson, F., Stimpson, J. P., & Pagán, J. A. (2016) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2016.04.019 · Cited by 164 · cited 5× · see citing works
“In addition, telecon-sultation (non-video remote consultations) was found to be more cost-effective than remote monitoring due to various devices and data usage costs [29].”
InfluentialLee, P. A., Greenfield, G., & Pappas, Y. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3274-8 · Cited by 162 · cited 1× · see citing works
“This is consistent with previous research on telehealth remote monitoring using Self-Monitoring of Blood Glucose (SMBG) transmission devices [52, 53].”
Shaw, S. E., Wherton, J. P., Vijayaraghavan, S., Morris, J. H., Bhattacharya, S., Hanson, P., Campbell-Richards, D., Ramoutar, S., Collard, A., Hodkinson, I., et al. (2018) · Health Services and Delivery Research · doi:10.3310/hsdr06210 · Cited by 142 · see citing works
Telehealth for diabetes self-management in primary healthcare: A systematic review and meta-analysis
So, C. F., & Chung, J. W. (2018) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x17700552 · Cited by 138 · cited 1× · see citing works
“Further, to specifically explore the effect of virtual care on HbA1c levels for type 2 diabetes, four reviews [31, 35, 42, 43] that did not provide disaggregated outcomes for type 2 diabetes were excluded for a sensitivity analysis.”
Samadbeik, M., Staib, A. N., Boyle, J., Khanna, S., Bosley, E., Bodnar, D., Lind, J., Austin, J. A., Tanner, S., Meshkat, Y., et al. (2024) · BMC Health Services Research · doi:10.1186/s12913-024-10725-6 · Cited by 107 · cited 1× · see citing works
“The scoring system that was used in a previously published systematic review was adopted [17], categorised a paper as "low quality" if its results were below 50%, "moderate quality" if they ranged between 50 and 69%, and "high quality" if the results were above 70%.”
Greenwood, D. A., Young, H. M., & Quinn, C. C. (2014) · Journal of Diabetes Science and Technology · doi:10.1177/1932296813519311 · Cited by 96 · see citing works
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Challenges in Diabetes Care: Can Digital Health Help Address Them?
Iyengar, V., Wolf, A., Brown, A. S., & Close, K. L. (2016) · Clinical Diabetes · doi:10.2337/diaclin.34.3.133 · Cited by 84 · cited 2× · see citing works
“Though face-to-face care will always have a role, virtual care has several advantages such as easier access, minimal wait times and no travel to clinics, therefore less expensive diabetes care [5].”
Huang, Z., Tao, H., Meng, Q., & Jing, L. (2015) · European Journal of Endocrinology · doi:10.1530/eje-14-0441 · Cited by 81 · see citing works
A virtual type 2 diabetes clinic using continuous glucose monitoring and endocrinology visits
Dixon, R. F., Zisser, H., Layne, J. E., Barleen, N. A., Miller, D. P., Moloney, D. P., Majithia, A. R., Gabbay, R. A., & Riff, J. (2020) · Journal of Diabetes Science and Technology · doi:10.1177/1932296819888662 · Cited by 80 · cited 1× · see citing works
“This review highlights the need for more research on the long-term impact, equity, and cost-effectiveness of comprehensive virtual care models, including video conferencing and telehealth devices [54].”
Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes: A meta-analysis
De Groot, J., Wu, D., Flynn, D., Robertson, D., Grant, G., & Sun, J. (2021) · World Journal of Diabetes · doi:10.4239/wjd.v12.i2.170 · Cited by 77 · see citing works
Cassimatis, M., & Kavanagh, D. J. (2012) · Journal of Telemedicine and Telecare · doi:10.1258/jtt.2012.gth105 · Cited by 73 · cited 4× · see citing works
“One review reported that short video messages on self-education topics sent to mobile phones every 24 h were effective, as participants who viewed 10 or more videos showed 0.6% reduction in HbA1c [23].”
InfluentialAnderson, A., O’Connell, S. S., Thomas, C., & Chimmanamada, R. (2022) · Journal of Racial and Ethnic Health Disparities · doi:10.1007/s40615-021-01174-6 · Cited by 70 · see citing works
Esmatjes, E., Jansà, M., Roca, D., Pérez-Ferre, N., del Valle, L., Martínez-Hervás, S., Ruiz de Adana, M., Linares, F., Batanero, R., Vázquez, F., et al. (2014) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2013.0313 · Cited by 64 · cited 1× · see citing works
“Previous research suggests that components of virtual care interventions lead to positive outcomes for people with type 2 diabetes such as improved blood glucose control and knowledge to manage their diabetes [9, 10].”
McLendon, S. F. (2017) · Diabetes Spectrum · doi:10.2337/ds16-0004 · Cited by 57 · cited 4× · see citing works
“Three reviews [32, 34, 44] reported that video conferencing was effective in improving HbA1c levels over periods ranging from 3–12 months.”
InfluentialHu, Y., Wen, X., Wang, F., Yang, D., Liu, S., Li, P., & Xu, J. (2019) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x18776823 · Cited by 57 · cited 1× · see citing works
“One review suggested that any evaluation less than 3 months would not be sufficient because of the time required to educate people with type 2 diabetes with virtual care systems or devices [30].”
Hossain, M. M., Tasnim, S., Sharma, R., Sultana, A., Shaik, A. F., Faizah, F., Kaur, R., Uppuluri, M., Sribhashyam, M., & Bhattacharya, S. (2019) · DIGITAL HEALTH · doi:10.1177/2055207619896153 · Cited by 57 · cited 4× · see citing works
“A total of 12 reviews analysed and reported a positive tendency on behavioural outcomes, whilst 2 reviews reported that virtual care improved medication adherence [27, 36].”
InfluentialHangaard, S., Laursen, S. H., Andersen, J. D., Kronborg, T., Vestergaard, P., Hejlesen, O., & Udsen, F. W. (2023) · Journal of Diabetes Science and Technology · doi:10.1177/19322968211064633 · Cited by 55 · cited 2× · see citing works
“Of those, 3 reviews reported telemonitoring combined with tele-education [44] and telemonitoring combined with healthcare professional feedback [45, 48] had greater effects.”
Coronavirus (COVID-19) – ‘Zoom’ Application Boon or BanePreprint
Chawla, A. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3606716 · Cited by 55 · see citing works
Robson, N., & Hosseinzadeh, H. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182212171 · Cited by 55 · cited 5× · see citing works
“A further 3 reviews reported that individualised feedback, either through automated algorithms or health care professionals, improved HbA1c control [24, 38, 48].”
InfluentialSim, R., & Lee, S. W. H. (2021) · Patient Preference and Adherence · doi:10.2147/ppa.s271449 · Cited by 50 · see citing works
Correia, J. C., Meraj, H., Teoh, S. H., Waqas, A., Ahmad, M., Lapão, L. V., Pataky, Z., & Golay, A. (2021) · Bulletin of the World Health Organization · doi:10.2471/blt.19.250068 · Cited by 42 · cited 5× · see citing works
“Six reviews reported the effect on self-management or care [22, 23, 26, 27, 35, 48], and 6 reported on self-efficacy [22, 27, 35, 36, 43, 46].”
InfluentialManski-Nankervis, J.-A., Furler, J., Blackberry, I., Young, D., O’Neal, D., & Patterson, E. (2014) · BMC Family Practice · doi:10.1186/1471-2296-15-20 · Cited by 41 · cited 1× · see citing works
“The quality of care is also compromised by time constraints and fragmented care [4].”
Su, D., McBride, C., Zhou, J., & Kelley, M. S. (2016) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x15608297 · Cited by 39 · cited 1× · see citing works
“There were 5 reviews evaluating virtual care components; 3 reviews [28, 31, 43] reported that interventions as simple as text-messaging or SMS feedback were equally effective in improving HbA1c, compared to a teleconference or telephone appointment with healthcare professionals.”
Eberle, C., & Stichling, S. (2021) · Journal of Medical Internet Research · doi:10.2196/23252 · Cited by 38 · see citing works
Jalil, S., Myers, T., & Atkinson, I. (2015) · Journal of Medical Systems · doi:10.1007/s10916-015-0191-9 · Cited by 37 · see citing works
McDaniel, C. C., Kavookjian, J., & Whitley, H. P. (2022) · Patient Education and Counseling · doi:10.1016/j.pec.2021.07.036 · Cited by 35 · cited 4× · see citing works
“Six reviews reported the effect on self-management or care [22, 23, 26, 27, 35, 48], and 6 reported on self-efficacy [22, 27, 35, 36, 43, 46].”
InfluentialWeb-Based Remote Monitoring Systems for Self-Managing Type 2 Diabetes: A Systematic Review
Mushcab, H., Kernohan, W. G., Wallace, J., & Martin, S. (2015) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2014.0296 · Cited by 34 · cited 1× · see citing works
“The extracted results for these outcomes were limited and heterogeneous, making it difficult to draw definitive conclusions about the effectiveness of virtual care on these parameters [40, 45].”
Michaud, T. L., Ern, J., Scoggins, D., & Su, D. (2021) · Telemedicine and e-Health · doi:10.1089/tmj.2019.0319 · Cited by 28 · cited 3× · see citing works
“Real-time feedback from health care professionals via video conferencing may be costly compared to automated telehealth interventions [24].”
González-Molero, I., Domínguez-López, M., Guerrero, M., Carreira, M., Caballero, F., Rubio-Martín, E., Linares, F., Cardona, I., Anarte, M. T., de Adana, M. S. R., et al. (2012) · Journal of Telemedicine and Telecare · doi:10.1258/jtt.2012.120103 · Cited by 24 · cited 1× · see citing works
“Previous research suggests that components of virtual care interventions lead to positive outcomes for people with type 2 diabetes such as improved blood glucose control and knowledge to manage their diabetes [9, 10].”
Wickramasinghe, S. I., Caffery, L. J., Bradford, N. K., & Smith, A. C. (2016) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x16673267 · Cited by 24 · cited 1× · see citing works
“Of the 8 reviews that assessed the effect of virtual care on quality of life [20, 22, 31, 32, 34, 35, 41, 44], 5 reported on cost and access barriers to health care.”
Diabetes management among underserved older adults through telemedicine and community health workers
Marsh, Z., Nguyen, Y., Teegala, Y., & Cotter, V. T. (2022) · Journal of the American Association of Nurse Practitioners · doi:10.1097/jxx.0000000000000595 · Cited by 22 · cited 5× · see citing works
“Six reviews reported the effect on self-management or care [22, 23, 26, 27, 35, 48], and 6 reported on self-efficacy [22, 27, 35, 36, 43, 46].”
InfluentialReview of Systematic Reviews in the Field of Telemedicine
Goharinejad, S., Hajesmaeel-Gohari, S., Jannati, N., Goharinejad, S., & Bahaadinbeigy, K. (2021) · Medical Journal of The Islamic Republic of Iran · doi:10.47176/mjiri.35.184 · Cited by 18 · cited 1× · see citing works
“One recent review [51] analysed the effect of telemedicine across all health conditions, with very few studies focusing on diabetes.”
Kaveh, M. H., Faradonbeh, M. R., & Kaveh, S. (2024) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x211052222 · Cited by 12 · cited 4× · see citing works
“Virtual care interventions were found to have greater effect among adults who were 50 years or older, with better treatment outcomes compared to younger adults reported in 5 reviews [21, 22, 26, 29, 36].”
Influential
Flagged first, then by citations
Research works printed but not linked: 1
- Covidence systematic review software, Veritas Health Innovation, Melbourne, Australia. Available at www.covidence.org.
Cited by
Sorted by citations
1. Improving Care and Promoting Health in Populations: Standards of Care in Diabetes—2026
Bajaj, M. S., McCoy, R. G., Balapattabi, K., Bannuru, R. R., Bellini, N. J., Bennett, A. K., Beverly, E. A., Early, K. B., ChallaSivaKanaka, S., Ebekozien, O. A., et al. (2025) · Diabetes Care · doi:10.2337/dc26-s001 · Cited by 64 · see citing works
Digital Health for Australia: Bridging the Rural, Regional, and Remote Health Gap
Mahmood, S., Huda, M. M., Ahmed, K. Y., Thapa, S., Astawesegn, F. H., Anyasodor, A. E., Moni, M. A., Shiddiky, M. J. A., Mondal, U. K., Aychiluhm, S. B., et al. (2025) · Interactive Journal of Medical Research · doi:10.2196/67460 · Cited by 4 · see citing works
“…Health outcomes (eg, hospital admission rates or disease-specific metrics such as HbA 1c also known as glycated hemoglobin levels for diabetes) [68,69] • Economic evaluations assessing cost-effectiveness considering patient travel, workforce efficiency, and avoided hospitalizations [40] •…”
Hoffmeister, L., Schuchardt, C., Hafke, A., Hummers, E., Dopfer‐Jablonka, A., Behrens, G. M. N., Stölting, A., Kuhnke, L. M., Schanz, J., Müller, F., et al. (2026) · Journal of Diabetes Investigation · doi:10.1111/jdi.70359 · Cited by 2 · see citing works
“Furthermore, SBC could not only support existing Disease Management Programs (DMP) for diabetes, but also allow them to be conducted through virtual visits 45, 46 .”
Expanding Technology-Enabled, Nurse-Delivered Chronic Disease Care
Crowley, M. J., Lewinski, A. A., Yang, Q., Hatch, D., Palipana, A., Bosworth, H. B., Kaufman, B. G., Chatterjee, R., Pennington, G., Matters, D., et al. (2026) · Annals of Internal Medicine · doi:10.7326/annals-26-00132 · Cited by 2 · see citing works
Ma, L., Zhao, W.-S., Wang, R., Huo, S.-S., Chu, S.-Y., Shi, L.-H., Chen, Y., & Zhong, Y. (2026) · BMC Endocrine Disorders · doi:10.1186/s12902-026-02183-4 · Cited by 3 · see citing works
“Our findings are consistent with the previous umbrella review [10], which included articles published before March 2022, and concluded that virtual care significantly improves clinical outcomes in people with type 2 diabetes, primarily affecting HbA1c.”
Sodeify, R., Seyednazari, M. A., Dorosti, A. M., & Nourazarian, A. (2026) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-026-07070-x · Cited by 1 · see citing works
“AI algorithms that synthesize CGM metrics, medication adherence reports, physical activity patterns, and dietary logs provide structured summaries highlighting emergent issues, potentially reducing con-sultation times while maintaining or improving patient satisfaction [256, 257].”
Murphy, G. T., Sampalli, T., Murdoch, J., King, C., Koto, P., Sim, M., MacInnis, M., Bragman, A., Salmaniw, S., Whelan, N., et al. (2025) · Digital Health · doi:10.1177/20552076251347011 · Cited by 1 · see citing works
“More recently, systematic reviews by Ezeamii et al. 44 and Ravi et al. 45 emphasized the transformative potential of telehealth in managing chronic conditions such as type 2 diabetes.”
Rodrigues, D. L. G., Belber, G. S., Maeyama, M. A., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-8117637/v1
Freeman, K., Tamale, J., Tamale, E., & Salerno, J. (2025) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2025.12.010
Chigusa, Y., Imatake, H., Komatsu, M., et al. (2026) · Cureus · doi:10.7759/cureus.102110
Outcomes in United States Veterans on Insulin Pumps Following Rapid Deployment of Telehealth Care
Orbell, S. L., Lund, B. C., Kim, N., Codario, R. A., Bandi, A., Mor, M. K., & Estock, J. L. (2026) · Diabetes Technology & Therapeutics · doi:10.1177/15209156251403561
“4 While VIPs adept at their own self-management as well as effective telehealth care may explain stable diabetes outcomes across the observation period, it is important to note that advances in hybrid closed loop algorithms integrated into many insulin pump models coincided with the observation…”
Tapia, C. B. M., Paz, M. M. C., Duchi, F. C. A., & Niama, A. N. C. (2026) · Esprint Investigación · doi:10.61347/ei.v5i1.267
Kowalska, A. M., Kuls, A. A., Sobol, A. Z., Pabis, B., Wiktorowicz, J. M., Kadłubańska, M., Bulińska, N., Sinczak, Z., Zembrzuska, S., & Bajerski, S. (2026) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.2(50).2026.5544
Cai, M., Lai, W. X., 彭卫群, Chen, J., & Zou, P. (2026) · BMC Oral Health · doi:10.1186/s12903-026-08527-9
“Although this review establishes a comprehensive, evidence-based framework for the synergistic management of diabetes and periodontitis, several inherent limitations”
Sousi, S., Greenfield, G., Hayhoe, B. W. J., Singh, N., Majeed, A., Darzi, A. W., & Neves, A. L. (2026) · Systematic Reviews · doi:10.1186/s13643-026-03244-4
“However, mixed results have been reported for safety and equity, with key determinants including lower digital literacy and the reduced opportunity for physical assessments [16, 17].”
Osafehinti, D. A., Thosani, S., & Weitzman, S. P. (2026) · Journal of Diabetes Science and Technology · doi:10.1177/19322968261470745
Yang, Z., Liu, Y., & Yang, H. (2026) · Chinese Medical Journal · doi:10.1097/cm9.0000000000004201
Diabetes and the role of primary care: a global perspective
Kar, P. S., Sathanapally, H., Aschner, P. J., Baatiema, L., Cheng, A., Gupta, Y., Hambling, C. E., Ma, R., Seidu, S., & Khunti, K. K. (2026) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(26)00214-7
Yehualashet, F. A., Baraki, A. G., Yeates, K., Harley, C., & Woo, K. Y. (2026) · JMIR Research Protocols · doi:10.2196/90739
“…the effectiveness of digital health technologies and mobile applications in diabetes management broadly, finding moderate improvements in glycemic control but noting significant heterogeneity in intervention design, population characteristics, intervention duration, and outcome measurement [34,35].”
- Authors
- Ravi, S., Meyerowitz-Katz, G., Yung, C., Ayre, J., McCaffery, K., Maberly, G., & Bonner, C.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Ravi, Sumathy
- ORCID
- Venue
- BMC Health Services Research
- Published
- 2025-03-06
- Volume
- 25
- Issue
- 1
- Pages
- 348-348
- ISSN
- 1472-6963 (ISSN-L)
- PMC
- PMC11884068
- OpenAlex
- W4408204132
- Semantic Scholar
- 5d2a4d2cdfa2800d4120a0af771f453b4aa8aec3
- Cited by
- 19
- References
- 50
- Citations by year
- 2026: 14 · 2025: 5
- FWCI
- 3.66
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Health Services Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- virtual care, type 2 diabetes, telemedicine, HbA1c, glycemic control, body mass index, medication adherence, self-management behavior, video-based intervention, primary care
- MeSH terms
- Systematic Reviews as Topic, Diabetes Mellitus, Type 2, Glycated Hemoglobin, Humans, Telemedicine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-29.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-29.
Cited sources are checked by gpt-6-sol.
Statistics and arithmetic are recomputed, not judged.
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