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Microalgae for the production of lipid and carotenoids: a review with focus on stress regulation and adaptation
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Microalgae have drawn great attention as promising sustainable source of lipids and carotenoids. Their lipid and carotenoids accumulation machinery can be trigged by the stress conditions such as nutrient limitation or exposure to the damaging physical factors. However, stressful conditions often adversely affect microalgal growth and cause oxidative damage to the cells, which can eventually reduce the yield of the desired products. To overcome these limitations, two-stage cultivation strategies and supplementation of growth-promoting agents have traditionally been utilized, but developing new highly adapted strains is theoretically the simplest strategy. In addition to genetic engineering, adaptive laboratory evolution (ALE) is frequently used to develop beneficial phenotypes in industrial microorganisms during long-term selection under specific stress conditions. In recent years, many studies have gradually introduced ALE as a powerful tool to improve the biological properties of microalgae, especially for improving the production of lipid and carotenoids. In this review, strategies for the manipulation of stress in microalgal lipids and carotenoids production are summarized and discussed. Furthermore, this review summarizes the overall state of ALE technology, including available selection pressures, methods, and their applications in microalgae for the improved production of lipids and carotenoids.
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Under stress conditions, microalgae can produce an abundance of value-added products such as lipids.
“Under stresscondition, microalgae can produce an abundance of valueadded products such as lipids [5].”
From Microalgae Lipids Detection and Quantification Method Towards Online Real-Time Monitoring: A Review (2023) · cites this paper as [5]
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Cites
Chisti, Y. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.02.001 · Cited by 9,524
Heterotrophic cultures of microalgae: Metabolism and potential products
Perez‐Garcia, O., Escalante, F. M. E., de‐Bashan, L. E., & Yoav Bashan, A. (2010) · Water Research · doi:10.1016/j.watres.2010.08.037 · Cited by 1,820
Cellular Defenses against Superoxide and Hydrogen Peroxide
Imlay, J. A. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.061606.161055 · Cited by 1,563
Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants
Kovtun, Y., Chiu, W.-L., Tena, G., & Sheen, J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.6.2940 · Cited by 1,532
Rubio, V., Linhares, F. S., Solano, R., Martin, A. C. B. M., Iglesias, J., Leyva, A., & Paz‐Ares, J. (2001) · Genes & Development · doi:10.1101/gad.204401 · Cited by 1,328
Increase in Chlorella strains calorific values when grown in low nitrogen medium
Illman, A. M., Scragg, A. H., & Shales, S. W. (2000) · Enzyme and Microbial Technology · doi:10.1016/s0141-0229(00)00266-0 · Cited by 1,008
Commercialization potential of microalgae for biofuels production
Singh, J., & Gu, S. (2010) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2010.06.014 · Cited by 1,001
Designer synthetic media for studying microbial-catalyzed biofuel production
Tang, X., Sousa, L. D. C., Jin, M., Chundawat, S. P. S., Chambliss, C. K., Lau, M. W., Xiao, Z., Dale, B. E., & Balan, V. (2015) · Biotechnology for Biofuels · doi:10.1186/s13068-014-0179-6 · Cited by 889
Adaptive laboratory evolution—Principles and applications for biotechnology
Dragosits, M., & Mattanovich, D. (2013) · Microbial Cell Factories · doi:10.1186/1475-2859-12-64 · Cited by 827
Effect of iron on growth and lipid accumulation in Chlorella vulgaris
Liu, Z., Wang, G., & Zhou, B. (2007) · Bioresource Technology · doi:10.1016/j.biortech.2007.09.073 · Cited by 815
Siaut, M., Cuiné, S., Cagnon, C., Fessler, B., Nguyen, H. M., Carrier, P., Beyly, A., Beisson, F., Triantaphylidès, C., Li‐Beisson, Y., et al. (2011) · BMC Biotechnology · doi:10.1186/1472-6750-11-7 · Cited by 754
Carotenoids from microalgae: A review of recent developments
Gong, M., & Bassi, A. S. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.10.005 · Cited by 747
Constraints to Commercialization of Algal Fuels
Chisti, Y. (2013) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2013.07.020 · Cited by 719
Adaptive response to oxidative stress: Bacteria, fungi, plants and animals
Lushchak, V. I. (2010) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2010.10.004 · Cited by 670
Renaud, S. M., Thinh, L.-V., Lambrinidis, G., & Parry, D. L. (2002) · Aquaculture · doi:10.1016/s0044-8486(01)00875-4 · Cited by 660
Takagi, M., Karseno, & Yoshida, T. (2006) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.101.223 · Cited by 651
Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae
Yuan, J., Peng, J., Yin, K., & Wang, J. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000414 · Cited by 649
Polyunsaturated fatty acids as antioxidants
Richard, D., Kefi, K., Barbe, U., Bausero, P., & Visioli, F. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.05.002 · Cited by 524
Ajjawi, I., Verruto, J., Aqui, M., Soriaga, L. B., Coppersmith, J. L., Kwok, K., Peach, L., Orchard, E. D., Kalb, R., Xu, W., et al. (2017) · Nature Biotechnology · doi:10.1038/nbt.3865 · Cited by 481
Timescales of Genetic and Epigenetic Inheritance
Rando, O. J., & Verstrepen, K. J. (2007) · Cell · doi:10.1016/j.cell.2007.01.023 · Cited by 472
Boyle, N. R., Page, M. D., Liu, B., Blaby, I. K., Casero, D., Kropat, J., Cokus, S. J., Hong‐Hermesdorf, A., Shaw, J., Karpowicz, S. J., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.334052 · Cited by 416
He, Y., Zhang, L., Zhang, J., & Bao, J. (2014) · Biotechnology for Biofuels · doi:10.1186/1754-6834-7-1 · Cited by 404
Phytohormones in microalgae: a new opportunity for microalgal biotechnology?
Lu, Y., & Xu, J. (2015) · Trends in Plant Science · doi:10.1016/j.tplants.2015.01.006 · Cited by 376
Skjånes, K., Rebours, C., & Lindblad, P. (2013) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2012.681625 · Cited by 352
Exploring the potential of algae/bacteria interactions
Kouzuma, A., & Watanabe, K. (2015) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2015.02.007 · Cited by 344
Peng, Q., Wang, X., Shang, M., Huang, J., Guan, G., Li, Y., & Shi, B. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-1 · Cited by 343
Evaluation of spirulina sp. growth in photoautotrophic, heterotrophic and mixotrophic cultures
Chojnacka, K., & Noworyta, A. (2004) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2003.12.002 · Cited by 340
Trends and novel strategies for enhancing lipid accumulation and quality in microalgae
Singh, P., Kumari, S., Guldhe, A., Misra, R., Rawat, I., & Bux, F. (2016) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2015.11.001 · Cited by 309 · cited 1×
“Microalgae can overproduce lipids or carotenoids under stress condition such as high salt, high light, or nutrient limitation [11, 12].”
BackgroundChen, X., Shekiro, J., Pschorn, T., Sabourin, M., Tao, L., Elander, R., Park, S., Jennings, E., Nelson, R., Trass, O., et al. (2014) · Biotechnology for Biofuels · doi:10.1186/1754-6834-7-98 · Cited by 300
Fu, W., Guðmundsson, Ó., Paglia, G., Herjólfsson, G., Andrésson, Ó. S., Palsson, B. Ø., & Brynjólfsson, S. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4502-5 · Cited by 289
Carotenoid and fatty acid metabolism in light‐stressed Dunaliella salina
Lamers, P. P., van de Laak, C. C. W., Kaasenbrood, P. S., Lorier, J., Janssen, M., de Vos, R. C. H., Bino, R. J., & Wijffels, R. H. (2010) · Biotechnology and Bioengineering · doi:10.1002/bit.22725 · Cited by 288
Wang, H., Zhang, B., Hao, Y., Huang, J. J., Tian, A., Liao, Y., Zhang, J., & Chen, S. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03268.x · Cited by 288
Jagadevan, S., Banerjee, A., Banerjee, C., Guria, C., Tiwari, R., Baweja, M., & Shukla, P. (2018) · Biotechnology for Biofuels · doi:10.1186/s13068-018-1181-1 · Cited by 275
Recent Developments on Genetic Engineering of Microalgae for Biofuels and Bio‐Based Chemicals
Ng, I., Tan, S., Kao, P., Chang, Y.-K., & Chang, J. (2017) · Biotechnology Journal · doi:10.1002/biot.201600644 · Cited by 257
Lipid composition of the red alga exposed to different levels of photon irradiance
Khotimchenko, S. V., & YAKOVLEVA, I. M. (2004) · Phytochemistry · doi:10.1016/j.phytochem.2004.10.024 · Cited by 245
Biological functions of carotenoids ‐ diversity and evolution
Vershinin, A. (1999) · BioFactors · doi:10.1002/biof.5520100203 · Cited by 240
Chokshi, K., Pancha, I., Ghosh, A., & Mishra, S. (2017) · Biotechnology for Biofuels · doi:10.1186/s13068-017-0747-7 · Cited by 238
Kao, P., & Ng, I. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.04.111 · Cited by 222
Aflalo, C., Meshulam, Y., Zarka, A., & Boussiba, S. (2007) · Biotechnology and Bioengineering · doi:10.1002/bit.21391 · Cited by 220
Factors affecting lipid accumulation by Nannochloropsis oculata in a two-stage cultivation process
Su, C., Chien, L., Gomes, J., Lin, Y., Yu, Y.-K., Liou, J.-S., & Syu, R.-J. (2010) · Journal of Applied Phycology · doi:10.1007/s10811-010-9609-4 · Cited by 219
Montibus, M., Pinson‐Gadais, L., Richard-Forget, F. C., Barreau, C., & Ponts, N. (2013) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2013.829416 · Cited by 215
de‐Bashan, L. E., Hani Antoun, A., & Yoav Bashan, A. (2008) · Journal of Phycology · doi:10.1111/j.1529-8817.2008.00533.x · Cited by 212
Functional genomics of lactic acid bacteria: from food to health
Douillard, F. P., & de Vos, W. M. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-s1-s8 · Cited by 209
Enhancement of microalgae growth and fatty acid content under the influence of phytohormones
Salama, E., Kabra, A. N., Ji, M.-K., Kim, J. R., Min, B., & Jeon, B. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.09.002 · Cited by 202
Two-stage cultures for the production of Astaxanthin from Haematococcus pluvialis
Fábregas, J., Otero, A., Maseda, A., & Domı́nguez, A. (2001) · Journal of Biotechnology · doi:10.1016/s0168-1656(01)00289-9 · Cited by 200
Piotrowska‐Niczyporuk, A., & Bajguz, A. (2013) · Plant Growth Regulation · doi:10.1007/s10725-013-9867-7 · Cited by 200
Gwak, Y., Hwang, Y., Wang, B., Kim, M., Jeong, J., Lee, C., Hu, Q., Han, D., & Jin, E. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/eru206 · Cited by 194
Cyanobacterial pigments: Perspectives and biotechnological approaches
Saini, D. K., Pabbi, S., & Shukla, P. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.08.002 · Cited by 194
Park, W.-K., Yoo, G., Moon, M., Kim, C. W., Choi, Y.-E., & Yang, J.-W. (2013) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-013-0386-9 · Cited by 184
Iwai, M., Ikeda, K., Shimojima, M., & Ohta, H. (2014) · Plant Biotechnology Journal · doi:10.1111/pbi.12210 · Cited by 182
Phytohormones and Effects on Growth and Metabolites of Microalgae: A Review
Han, X., Huiru, Z., Bartocci, P., Fantozzi, F., & Yan, Y. (2018) · Fermentation · doi:10.3390/fermentation4020025 · Cited by 179
Fu, W., Gudmundsson, O., Feist, A. M., Herjolfsson, G., Brynjolfsson, S., & Palsson, B. Ø. (2012) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2012.07.004 · Cited by 170
Li, D., Wang, L., Zhao, Q., Wei, W., & Sun, Y. (2015) · Bioresource Technology · doi:10.1016/j.biortech.2015.03.011 · Cited by 164
Self-citationHormonal control of the plant cell cycle
del Pozo, J. C., López-Matas, M. A., Ramírez-Parra, E., & Gutiérrez, C. (2004) · Physiologia Plantarum · doi:10.1111/j.1399-3054.2004.00420.x · Cited by 153
Kang, N. K., Jeon, S., Kwon, S., Koh, H. G., Shin, S.-E., Lee, B., Choi, G., Yang, J.-W., Jeong, B., & Chang, Y. K. (2015) · Biotechnology for Biofuels · doi:10.1186/s13068-015-0386-9 · Cited by 152
Xie, Y., Ho, S.-H., Chen, C.-N. N., Chen, C.-Y., Ng, I.-S., Jing, K.-J., Chang, J.-S., & Lu, Y. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.06.064 · Cited by 151
Sun, X., Ren, L., Bi, Z.-Q., Ji, X., Zhao, Q., Jiang, L., & Huang, H. (2018) · Biotechnology for Biofuels · doi:10.1186/s13068-018-1065-4 · Cited by 145
Self-citationSun, X., Ren, L., Bi, Z.-Q., Ji, X., Zhao, Q., & Huang, H. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.07.079 · Cited by 141
Self-citationRen, L., Sun, X., Ji, X., Chen, S., Guo, D., & Huang, H. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.10.040 · Cited by 137
Self-citationBajhaiya, A. K., Dean, A. P., Zeef, L. A. H., Webster, R. E., & Pittman, J. K. (2015) · PLANT PHYSIOLOGY · doi:10.1104/pp.15.01907 · Cited by 135
Coesel, S., Baumgartner, A., Teles, L. M., Ramos, A., Henriques, N., Cancela, M. L., & Varela, J. C. S. (2008) · Marine Biotechnology · doi:10.1007/s10126-008-9100-2 · Cited by 134
Choix, F. J., de-Bashan, L. E., & Bashan, Y. (2012) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2012.07.012 · Cited by 133
Fan, J., Huang, J., Li, Y., Han, F., Wang, J., Li, X., Wang, W., & Li, S. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.02.046 · Cited by 127
Yoshioka, S., Taniguchi, F., Miura, K., Inoue, T., Yamano, T., & Fukuzawa, H. (2004) · The Plant Cell · doi:10.1105/tpc.021162 · Cited by 127
Lu, Y., Tarkowská, D., Turečková, V., Luo, T., Yi, X., Li, J., Wang, Q., Jiao, N., Strnad, M., & Xu, J. (2014) · The Plant Journal · doi:10.1111/tpj.12615 · Cited by 126
Hormonal Control of the Plant Cell Cycle
Roef, L., & Onckelen, H. A. V. (2004) · Biotechnology in agriculture and forestry · doi:10.1007/978-3-662-10572-6_10 · Cited by 124
Wan, M., Zhang, J., Hou, D., Fan, J., Li, Y., Huang, J., & Wang, J. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.06.030 · Cited by 124
Hirt, H. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.6.2405 · Cited by 124
Zhang, J., Hao, Q., Bai, L., Xu, J., Yin, W.-B., Song, L., Xu, L., Guo, X., Fan, C., Chen, Y., et al. (2014) · Biotechnology for Biofuels · doi:10.1186/s13068-014-0128-4 · Cited by 122
Identification of regulatory network hubs that control lipid metabolism in Chlamydomonas reinhardtii
Gargouri, M., Park, J.-J., Holguin, F. O., Kim, M., Wang, H., Deshpande, R. R., Shachar‐Hill, Y., Hicks, L. M., & Gang, D. R. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv217 · Cited by 121
Ra, C.-H., Kang, C.-H., Jung, J.-H., Jeong, G., & Kim, S.-K. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.04.059 · Cited by 121
Evolution of salt tolerance in a laboratory reared population of C hlamydomonas reinhardtii
Perrineau, M., Zelzion, E., Gross, J., Price, D. C., Boyd, J. M., & Bhattacharya, D. (2013) · Environmental Microbiology · doi:10.1111/1462-2920.12372 · Cited by 120
Lineage-specific chromatin signatures reveal a regulator of lipid metabolism in microalgae
Ngan, C. Y., Wong, C., Choi, C., Yoshinaga, Y., Louie, K., Jia, J., Chen, C., Bowen, B. P., Cheng, H., Leonelli, L., et al. (2015) · Nature Plants · doi:10.1038/nplants.2015.107 · Cited by 119
Tsai, C., Warakanont, J., Takeuchi, T., Sears, B. B., Moellering, E. R., & Benning, C. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1414567111 · Cited by 118
Osundeko, O., Davies, H. S., & Pittman, J. K. (2013) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2013.05.027 · Cited by 118
Ibáñez-Salazar, A., Rosales‐Mendoza, S., Rocha‐Uribe, A., Ramírez-Alonso, J. I., Lara-Hernández, I., Hernández-Torres, A., Paz-Maldonado, L. M. T., Silva‐Ramírez, A. S., Bañuelos-Hernández, B., Martínez-Salgado, J. L., et al. (2014) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2014.05.003 · Cited by 118
Giridhar Babu, A., Wu, X., Kabra, A. N., & Kim, D.-P. (2017) · Algal Research · doi:10.1016/j.algal.2017.02.004 · Cited by 118
Gao, Z., Meng, C., Zhang, X., Xu, D., Miao, X., Wang, Y., Yang, L. M., Lv, H., Chen, L., & Ye, N. (2012) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2012.07.001 · Cited by 117
Effects of abiotic stressors on lutein production in the green microalga Dunaliella salina
Fu, W., Paglia, G., Magnúsdóttir, M., Steinarsdóttir, E. A., Guðmundsson, S., Palsson, B. Ø., Andrésson, Ó. S., & Brynjólfsson, S. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-3 · Cited by 116
Wan, M., Zhang, Z., Wang, J., Huang, J., Fan, J., Yu, A., Wang, W., & Li, Y. (2015) · Bioresource Technology · doi:10.1016/j.biortech.2015.09.031 · Cited by 113
Yoshida, K., Igarashi, E., MUKAI, M., Hirata, K., & Miyamoto, K. (2003) · Plant Cell & Environment · doi:10.1046/j.1365-3040.2003.00976.x · Cited by 113
Liu, B., Liu, J., Sun, P., Ma, X., Jiang, Y., & Chen, F. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b01441 · Cited by 109
Sun, X., Ren, L., Ji, X., Chen, S., Guo, D., & Huang, H. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.03.093 · Cited by 109
Self-citationYoneda, A., Henson, W. R., Goldner, N. K., Park, K. J., Forsberg, K. J., Kim, S. J., Pesesky, M. W., Foston, M. B., Dantas, G. A., & Moon, T. S. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw055 · Cited by 108
Yoshida, K., Igarashi, E., 若月, 映., Miyamoto, K., & Hirata, K. (2004) · Plant Science · doi:10.1016/j.plantsci.2004.07.002 · Cited by 107
Lu, Y., Jiang, P., Liu, S., Gan, Q., Cui, H., & Qin, S. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.03.072 · Cited by 103
Jiang, Y., & Chen, F. (2000) · Journal of the American Oil Chemists' Society · doi:10.1007/s11746-000-0099-0 · Cited by 99
Park, J. C., Choi, S. P., Hong, M.-E., & Sim, S. J. (2014) · Bioprocess and Biosystems Engineering · doi:10.1007/s00449-014-1180-y · Cited by 98
Baek, S., Kwon, E. Y., Bae, S., Cho, B., Kim, S., & Hahn, J. (2017) · Biotechnology Journal · doi:10.1002/biot.201700015 · Cited by 97
High lipid productivity of an Ankistrodesmus – Rhizobium artificial consortium
Nascimento, M. D., Dublan, M. D. L. Á., Ortiz-Marquez, J. C. F., & Curatti, L. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.07.085 · Cited by 95
Improvements in algal lipid production: a systems biology and gene editing approach
Banerjee, A., Banerjee, C., Negi, S., Chang, J., & Shukla, P. (2017) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2017.1356803 · Cited by 95
Liu, J., Qiu, W., & Song, Y. (2016) · Algal Research · doi:10.1016/j.algal.2016.06.027 · Cited by 91
Gao, Z., Meng, C., Zhang, X., Xu, D., Zhao, Y., Wang, Y., Lv, H., Yang, L., Chen, L., & Ye, N. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042243 · Cited by 90
Zhang, S., He, Y., Sen, B., Chen, X., Xie, Y., Keasling, J. D., & Wang, G. (2018) · Metabolic Engineering Communications · doi:10.1016/j.meteno.2018.03.002 · Cited by 90
Yi, Z., Xu, M., Magnúsdóttir, M., Zhang, Y., Brynjólfsson, S., & Fu, W. (2015) · Marine Drugs · doi:10.3390/md13106138 · Cited by 86
Wang, D., Ju, X.-M., Zhou, D., & Wei, G. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.04.036 · Cited by 85
Sulochana, S. B., & Arumugam, M. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.02.078 · Cited by 84
Liu, T., Liu, F., Wang, C., Wang, Z., & Li, Y. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.02.004 · Cited by 79
Metabolic engineering of Dunaliella salina for production of ketocarotenoids
Anila, N., Simon, D. P., Chandrashekar, A., Ravishankar, G. A., & Sarada, R. (2015) · Photosynthesis Research · doi:10.1007/s11120-015-0188-8 · Cited by 78
Iwai, M., Hori, K., Sasaki‐Sekimoto, Y., Shimojima, M., & Ohta, H. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00912 · Cited by 78
Río, E. D., Acién, F. G., García‐Malea, M. C., Rivas, J., Grima, E. M., & Guerrero, M. G. (2007) · Biotechnology and Bioengineering · doi:10.1002/bit.21770 · Cited by 78
Kato, Y., Ho, S., Vavricka, C. J., Chang, J., Hasunuma, T., & Kondo, A. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.06.035 · Cited by 75
Ra, C. H., Kang, C.-H., Kim, N. K., Lee, C., & Kim, S.-K. (2015) · Renewable Energy · doi:10.1016/j.renene.2015.02.002 · Cited by 74
Lee, D., Feist, A. M., Barrett, C. L., & Palsson, B. Ø. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026172 · Cited by 73
Solubility of recombinant Src homology 2 domains expressed in E. colican be predicted by TANGO
Andersen, T. C. B., Lindsjø, K., Hem, C. D., Koll, L., Kristiansen, P. E., Skjeldal, L., Andreotti, A. H., & Spurkland, A. (2014) · BMC Biotechnology · doi:10.1186/1472-6750-14-3 · Cited by 72
Sun, H., Liu, B., Lu, X., Cheng, K., & Chen, F. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.03.011 · Cited by 71
Cheng, J., Li, K., Yang, Z., Lu, H., Zhou, J., & Cen, K. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.05.095 · Cited by 70
Ho, S., Xie, Y., Chan, M.-C., Liu, C.-C., Chen, C., Lee, D., Huang, C., & Chang, J. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.10.062 · Cited by 69
Kajikawa, M., Sawaragi, Y., Shinkawa, H., Yamano, T., Ando, A., Kato, M., Hirono, M., Sato, N., & Fukuzawa, H. (2015) · PLANT PHYSIOLOGY · doi:10.1104/pp.15.00319 · Cited by 69
Wang, Y., Shi, M., Niu, X., Zhang, X., Gao, L., Chen, L., Wang, J., & Zhang, W. (2014) · Microbial Cell Factories · doi:10.1186/s12934-014-0151-y · Cited by 68
Kurosawa, K., Radek, A., Plassmeier, J. K., & Sinskey, A. J. (2015) · Biotechnology for Biofuels · doi:10.1186/s13068-015-0209-z · Cited by 65
Functional and Metabolic Effects of Adaptive Glycerol Kinase (GLPK) Mutants in Escherichia coli
Applebee, M. K., Joyce, A. R., Conrad, T. M., Pettigrew, D. W., & Palsson, B. Ø. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.195305 · Cited by 64
Chen, C., Kao, A.-L., Tsai, Z.-C., Shen, Y., Kao, P., Ng, I., & Chang, J. (2017) · Biotechnology Journal · doi:10.1002/biot.201700204 · Cited by 63
Yu, S., Zhao, Q., Miao, X., & Shi, J. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.08.069 · Cited by 62
Self-citationLi, X., Pei, G., Liu, L., Chen, L., & Zhang, W. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.03.049 · Cited by 62
Banerjee, C., Singh, P. K., & Shukla, P. (2016) · Biotechnology Journal · doi:10.1002/biot.201500284 · Cited by 58
Enhanced astaxanthin production from a novel strain of Haematococcus pluvialis using fulvic acid
Zhao, Y., Minmin, S., Xu, J., Zhao, P., Li, T., & Yu, X. (2015) · Process Biochemistry · doi:10.1016/j.procbio.2015.09.004 · Cited by 58
Salas-Montantes, C. J., González‐Ortega, O., Ochoa‐Alfaro, A. E., Camarena-Rangel, R., Paz-Maldonado, L. M. T., Rosales‐Mendoza, S., Rocha‐Uribe, A., & Soria‐Guerra, R. E. (2018) · Journal of Applied Phycology · doi:10.1007/s10811-018-1393-6 · Cited by 56
Flórez-Miranda, L., Cañizares-Villanueva, R. O., Melchy-Antonio, O., Martínez-Jerónimo, F., & Flores- Ortíz, C. M. (2017) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2017.09.002 · Cited by 53
Salt-induced osmotic stress for lipid overproduction in batch culture of Chlorella vulgaris
Duan, X. (2012) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb11.3670 · Cited by 53
Li, Y., Xu, H., Han, F., Mu, J., Chen, D., Feng, B., & Zeng, H. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.07.028 · Cited by 52
Tzovenis, I. P., Pauw, N. D., & Sorgeloos, P. (1997) · Aquaculture International · doi:10.1023/a:1018349131522 · Cited by 51
Bajhaiya, A. K., Dean, A. P., Driver, T., Trivedi, D. K., Rattray, N. J. W., Allwood, J. W., Goodacre, R., & Pittman, J. K. (2016) · Metabolomics · doi:10.1007/s11306-015-0878-4 · Cited by 49
Velmurugan, N., Sung, M., Yim, S. S., Park, M. S., Yang, J. W., & Jeong, K. J. (2014) · Biotechnology for Biofuels · doi:10.1186/s13068-014-0117-7 · Cited by 48
Response mechanism of the docosahexaenoic acid producer Aurantiochytrium under cold stress
Ma, Z., Tian, M., Tan, Y., Cui, G., Feng, Y., Cui, Q., & Song, X. (2017) · Algal Research · doi:10.1016/j.algal.2017.05.021 · Cited by 48
Wensel, P., Helms, G., Hiscox, B., Davis, W. C., Kirchhoff, H., Bule, M. V., Yu, L., & Chen, S. (2014) · Algal Research · doi:10.1016/j.algal.2013.12.005 · Cited by 47
Liang, M., & Jiang, J. (2017) · Scientific Reports · doi:10.1038/srep37025 · Cited by 46
Using Natural Selection to Explore the Adaptive Potential of Chlamydomonas reinhardtii
Perrineau, M., Gross, J., Zelzion, E., Price, D. C., Levitan, O., Boyd, J. M., & Bhattacharya, D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092533 · Cited by 38
Tillich, U. M., Wolter, N., Franke, P., Dühring, U., & Frohme, M. (2014) · BMC Biotechnology · doi:10.1186/1472-6750-14-66 · Cited by 36
Genomic analysis of parallel-evolved cyanobacterium Synechocystis sp. PCC 6803 under acid stress
Uchiyama, J., Kanesaki, Y., Iwata, N., Asakura, R., Funamizu, K., Tasaki, R., Agatsuma, M., Tahara, H., Matsuhashi, A., Yoshikawa, H., et al. (2015) · Photosynthesis Research · doi:10.1007/s11120-015-0111-3 · Cited by 34
The Steady States of Microbial Growth on Mixtures of Substitutable Substrates in a Chemostat
Narang, A. (1998) · Journal of Theoretical Biology · doi:10.1006/jtbi.1997.0552 · Cited by 33
The role of cellular objectives and selective pressures in metabolic pathway evolution
Nam, H., Conrad, T. M., & Lewis, N. E. (2011) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2011.03.006 · Cited by 32
Lu, L., Wei, L., Zhu, K. Y., Wei, D., & Hua, Q. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.03.013 · Cited by 32
Shin, S.-E., Koh, H. G., Kang, N. K., Suh, W. I., Jeong, B., Lee, B., & Chang, Y. K. (2017) · Biotechnology for Biofuels · doi:10.1186/s13068-017-1000-0 · Cited by 32
Gaffney, M., O’Rourke, R., & Murphy, R. A. (2014) · Algal Research · doi:10.1016/j.algal.2014.03.005 · Cited by 31
Impact of Signal Peptides on Furin‐2A Mediated Monoclonal Antibody Secretion in CHO Cells
Lin, J., Neo, S. H., Ho, S. C. L., Yeo, J. H. M., Wang, T., Zhang, W., Bi, X., Chao, S., & Yang, Y. (2017) · Biotechnology Journal · doi:10.1002/biot.201700268 · Cited by 31
Singh, D., Mathur, A. S., Tuli, D. K., Puri, M., & Barrow, C. J. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.03.022 · Cited by 29
Effects of NaCl and KNO3 concentrations on the abscisic acid content of Dunaliella sp. (Chlorophyta)
Tominaga, N., Takahata, M., & Tominaga, H. (1993) · Springer eBooks · doi:10.1007/978-94-011-2076-0_12 · Cited by 27
Effects of NaCl and KNO3 concentrations on the abscisic acid content of Dunaliella sp. (Chlorophyta)
Tominaga, N., Takahata, M., & Tominaga, H. (1993) · Hydrobiologia · doi:10.1007/bf00018798 · Cited by 27
Wu, S., Meng, Y., Cao, X., & Xue, S. (2016) · Algal Research · doi:10.1016/j.algal.2016.05.025 · Cited by 26
Repeated nitrogen starvation doesn’t affect lipid productivity of Chlorococcum littorale
Cabanelas, I. T. D., Kleinegris, D. M. M., Wijffels, R. H., & Barbosa, M. J. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.08.009 · Cited by 23
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Raynes, Y., Halstead, A. M., & Sniegowski, P. (2013) · Journal of Evolutionary Biology · doi:10.1111/jeb.12284 · Cited by 20
Hacking an Algal Transcription Factor for Lipid Biosynthesis
Chen, X., Hu, G., & Liu, L. (2018) · Trends in Plant Science · doi:10.1016/j.tplants.2017.12.008 · Cited by 19
Liu, J., Qiu, W., Song, Y., Peng, H., & Zhao, Y. (2017) · Environmental Progress & Sustainable Energy · doi:10.1002/ep.12547 · Cited by 14
Banerjee, A., Kumar, N., Varjani, S., Guria, C., Bandopadhyay, R., Shukla, P., & Banerjee, C. (2017) · Energy, environment, and sustainability · doi:10.1007/978-981-10-7434-9_13 · Cited by 14
Trinh, T. C., Trần, H. T., & Bui, T. V. (2017) · AIP conference proceedings · doi:10.1063/1.5000185 · Cited by 13
Kim, H. J., Jeong, H., Hwang, S., Lee, M., Lee, Y. J., Lee, D.-W., & Lee, S. J. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00476 · Cited by 13
Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat
Jeong, H., Lee, S. J., & Kim, P. (2016) · Journal of Visualized Experiments · doi:10.3791/54446 · Cited by 12
Khasin, M., Cahoon, R. E., Alvarez, S., Beckeris, R., Eyun, S., Jia, Q., Riethoven, J.-J. M., Nickerson, K. W., & Riekhof, W. R. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/180547 · Cited by 12
Nugroho, W. A., Nurlaili, F. R., Hendrawan, Y., & Argo, B. D. (2015) · International Journal on Advanced Science Engineering and Information Technology · doi:10.18517/ijaseit.5.5.586 · Cited by 9
Functions of carotenoids: diversity and evolution
Vershinin, A. (1999) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/s1095-6433(99)90448-8 · Cited by 2
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Zanchetta, E., Damergi, E., Patel, B., Borgmeyer, T., Pick, H. M., Pulgarin, A., & Ludwig, C. D. R. (2021) · Algal Research · doi:10.1016/j.algal.2021.102288 · Cited by 233
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Capson-Tojo, G., Batstone, D. J., Grassino, M., Vlaeminck, S. E., Puyol, D., Verstraete, W., Kleerebezem, R., Oehmen, A., Ghimire, A., Pikaar, I., et al. (2020) · Biotechnology Advances · doi:10.1016/j.biotechadv.2020.107567 · Cited by 228
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Gauthier, M. R., Senhorinho, G. N. A., & Scott, J. A. (2020) · Algal Research · doi:10.1016/j.algal.2020.102104 · Cited by 214
Song, X., Liu, B.-F., Kong, F., Ren, N., & Ren, H. (2022) · Resources Conservation and Recycling · doi:10.1016/j.resconrec.2022.106355 · Cited by 203
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Mota, G. F., de Sousa, I. G., de Oliveira, A. L. B., Cavalcante, A. L. G., Moreira, K. D. S., Cavalcante, F. T. T., Souza, J. E. D. S., Falcão, Í. R. D. A., Rocha, T. G., Valério, R. B. R., et al. (2022) · Algal Research · doi:10.1016/j.algal.2021.102616 · Cited by 160
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Yap, J. K., Sankaran, R., Chew, K. W., Halimatul Munawaroh, H. S., Ho, S.-H., Rajesh Banu, J., & Show, P. L. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2021.130886 · Cited by 138
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Zienkiewicz, A., Zienkiewicz, K., Poliner, E., Pulman, J. A., Du, Z., Stefano, G., Tsai, C., Horn, P. J., Feußner, I., Farré, E. M., et al. (2019) · PLANT PHYSIOLOGY · doi:10.1104/pp.19.00854 · Cited by 103
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Self-citationRokicka, M., Zieliński, M., Dudek, M., & Dębowski, M. (2020) · BioEnergy Research · doi:10.1007/s12155-020-10202-y · Cited by 85
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Song, X., Liu, B.-F., Kong, F., Song, Q., Ren, N., & Ren, H.-Y. (2024) · Water Research · doi:10.1016/j.watres.2024.121134 · Cited by 75
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Narang, P. K., Dey, J., Mahapatra, S. R., Roy, R., Kushwaha, G. S., Misra, N., Suar, M., & Raina, V. (2021) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-021-03188-y · Cited by 72
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Maroneze, M. M., Zepka, L. Q., Lopes, E. J., Pérez‐Gálvez, A., & Roca, M. (2019) · Antioxidants · doi:10.3390/antiox8120600 · Cited by 70
Ferreira, G. F., Pinto, L. F. R., Carvalho, P. D. O., Coelho, M. B., Eberlin, M. N., Filho, R. M., & Fregolente, L. V. (2019) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-019-00566-3 · Cited by 70
Ahmad, S., Iqbal, K., Kothari, R., Singh, H. M., Sarı, A., & Tyagi, V. V. (2022) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2022.03.015 · Cited by 70
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Hawrot-Paw, M., Ratomski, P., Koniuszy, A., Golimowski, W., Teleszko, M., & Grygier, A. (2021) · Energies · doi:10.3390/en14217334 · Cited by 67
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Chen, J.-H., Kato, Y., Matsuda, M., Chen, C., Nagarajan, D., Hasunuma, T., Kondo, A., & Chang, J. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.125200 · Cited by 61
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Ding, W., Li, Q., Han, B., Zhao, Y., Geng, S., Ning, D., Ma, T., & Yu, X. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2019.122002 · Cited by 59
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Chawla, H., Singh, S. K., & Haritash, A. K. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-31295-w · Cited by 57
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Falfushynska, H. (2024) · Phycology · doi:10.3390/phycology4040030 · Cited by 55
Canelli, G., Neutsch, L., Carpine, R., Tevere, S., Giuffrida, F., Rohfritsch, Z., Dionisi, F., Bolten, C. J., & Mathys, A. (2019) · Algal Research · doi:10.1016/j.algal.2019.101754 · Cited by 55
Nishshanka, G. K. S. H., Liyanaarachchi, V. C., Premaratne, M., Nimarshana, P. H. V., Ariyadasa, T. U., & Kornaros, M. E. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.126018 · Cited by 55
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Patle, D. S., Pandey, A., Srivastava, S., Sawarkar, A. N., & Kumar, S. (2020) · Environmental Chemistry Letters · doi:10.1007/s10311-020-01080-z · Cited by 52
Chang, R. L., Stanley, J. A., Robinson, M. C., Sher, J. W., Li, Z., Chan, Y. A., Omdahl, A. R., Wattiez, R., Godzik, A., & Surget, S. M. (2020) · The EMBO Journal · doi:10.15252/embj.2020104523 · Cited by 51
Ugya, A. Y., Li, X., Chen, H., & Wang, Q. (2024) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2024.114266 · Cited by 51
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Self-citationAhmad, A., BANAT, F. A., AlSafar, H. S., & Hasan, S. W. (2022) · Phytochemistry Reviews · doi:10.1007/s11101-022-09804-5 · Cited by 43
Dias, C. T., Santos, J. A. L., dos Reis, A. J. D., & da Silva, T. L. (2023) · Waste and Biomass Valorization · doi:10.1007/s12649-023-02032-8 · Cited by 43
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Park, S., Ahn, Y., Pandi, K., Ji, M.-K., Yun, H.-S., & Choi, J.-Y. (2019) · Energies · doi:10.3390/en12183497 · Cited by 39
Metadata
- Authors
- Sun, X.-M., Ren, L.-J., Zhao, Q.-Y., Ji, X.-J., & Huang, H.
- Affiliations
- Nanjing Tech University (CN)
- Venue
- Biotechnology for Biofuels
- Published
- 2018-10-04
- Volume
- 11
- Issue
- 1
- Pages
- 272-272
- ISSN
- 1754-6834 (ISSN-L)
- PMC
- PMC6171298
- OpenAlex
- W2895529302
- Cited by
- 470
- References
- 151
- Citations by year
- 2026: 49 · 2025: 56 · 2024: 73 · 2023: 56 · 2022: 79 · 2021: 66 · 2020: 61 · 2019: 29
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Biotechnology for Biofuels (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Government of Jiangsu Province (XTE1829)
- Jiangsu National Synergistic Innovation Center for Advanced Materials (XTC1810, XTE1829)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Keywords
- microalgae, lipid production, carotenoid production, stress adaptation, adaptive laboratory evolution, oxidative stress, nutrient limitation, two-stage cultivation, genetic engineering, selection pressure, industrial microorganisms
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