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Social defeat: Risk factor for schizophrenia?
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Summary: The hypothesis that chronic and long-term experience of ‘social defeat’ may increase the risk for schizophrenia is proposed. This increased risk may result from sensitisation of the mesolimbic dopamine system and/or increased baseline activity of this system. Data supporting the social defeat hypothesis are presented.
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“Many of the environmental risk factors associated with schizophrenia can be broadly conceptualised as chronic psychosocial stressors (Selten and Cantor-Graae, 2005; Walker and Diforio, 1997).”
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Metadata
- Authors
- Selten, J.-P., & Cantor-Graae, E.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2005-08
- Volume
- 187
- Issue
- 2
- Pages
- 101-102
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2135074722
- Cited by
- 551
- References
- 2
- FWCI
- 8.06
- Type
- journal article
- Language
- en
- Open access
- bronze
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