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Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

Desvergne, Béatrice, Wahli, Walter·1999·Endocrine Reviews

Abstract

I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA binding properties C. PPAR ligand-binding properties D. Alternative pathways for PPAR activation E. PPAR-mediated transactivation properties III. Physiological Aspects A. Differential expression of PPAR mRNAs B. PPAR target genes and functions in fatty acid metabolism C. PPARs and control of inflammatory responses D. PPARs and atherosclerosis E. PPARs and the development of the fetal epidermal permeability barrier F. PPARs, carcinogenesis, and control of the cell cycle IV. Conclusions

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Metadata

Authors
Desvergne, B., & Wahli, W.
Venue
Endocrine Reviews
Published
1999-10-01
Volume
20
Issue
5
Pages
649-688
ISSN
  • 0163-769X (ISSN-L)
  • 1945-7189
OpenAlex
W2022048961
Cited by
3,086
References
25
FWCI
29.80
Type
journal article
Language
en
Open access
closed

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