The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology

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GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function

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Common variants near MC4R are associated with fat mass, weight and risk of obesity

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Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure

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Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

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Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

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The central melanocortin system directly controls peripheral lipid metabolism

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The Neuroendocrine Circuitry Controlled by POMC, MSH, and AGRP

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Current Therapeutic Targets in Cancer Cachexia: A Pathophysiologic Approach

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Activation of MAPK by inverse agonists in six naturally occurring constitutively active mutant human melanocortin-4 receptors

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Leveraging Melanocortin Pathways to Treat Glomerular Diseases

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MC4R Agonists: Structural Overview on Antiobesity Therapeutics

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Functional studies on twenty novel naturally occurring melanocortin-4 receptor mutations

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