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Cited by 1,093

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Vitamin D intake and incidence of multiple sclerosis

Munger, K. L., Zhang, S. M., O’Reilly, E., Hernán, M. A., Olek, M. J., Willett, W. C., Ascherio, A.·2004·Neurology
DOI 10.1212/01.wnl.0000101723.79681.38
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Abstract

BACKGROUND: A protective effect of vitamin D on risk of multiple sclerosis (MS) has been proposed, but no prospective studies have addressed this hypothesis. METHODS: Dietary vitamin D intake was examined directly in relation to risk of MS in two large cohorts of women: the Nurses' Health Study (NHS; 92,253 women followed from 1980 to 2000) and Nurses' Health Study II (NHS II; 95,310 women followed from 1991 to 2001). Diet was assessed at baseline and updated every 4 years thereafter. During the follow-up, 173 cases of MS with onset of symptoms after baseline were confirmed. RESULTS: The pooled age-adjusted relative risk (RR) comparing women in the highest quintile of total vitamin D intake at baseline with those in the lowest was 0.67 (95% CI = 0.40 to 1.12; p for trend = 0.03). Intake of vitamin D from supplements was also inversely associated with risk of MS; the RR comparing women with intake of >or=400 IU/day with women with no supplemental vitamin D intake was 0.59 (95% CI = 0.38 to 0.91; p for trend = 0.006). No association was found between vitamin D from food and MS incidence. CONCLUSION: These results support a protective effect of vitamin D intake on risk of developing MS.

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Research works printed but not linked: 33

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Cited by

Metadata

Authors
Munger, K. L., Zhang, S. M., O’Reilly, E., Hernán, M. A., Olek, M. J., Willett, W. C., & Ascherio, A.
Venue
Neurology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2004-01-13
Volume
62
Issue
1
Pages
60-65
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
DOI
10.1212/01.wnl.0000101723.79681.38
OpenAlex
W2056247628
Cited by
1,093
References
2
FWCI
29.59
Type
journal article
Language
en
Open access
closed

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